Aliases & Classifications for Discitis

MalaCards integrated aliases for Discitis:

Name: Discitis 12 44 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:10986
ICD10 33 M46.4
MeSH 44 D015299
SNOMED-CT 68 2304001
UMLS 73 C0012624

Summaries for Discitis

MalaCards based summary : Discitis is related to epidural abscess and septic arthritis. An important gene associated with Discitis is CALCA (Calcitonin Related Polypeptide Alpha). The drugs Anti-Bacterial Agents and Antibiotics, Antitubercular have been mentioned in the context of this disorder. Affiliated tissues include bone, testes and liver.

Wikipedia : 76 Discitis or diskitis is an infection in the intervertebral disc space that affects different age groups.... more...

Related Diseases for Discitis

Graphical network of the top 20 diseases related to Discitis:



Diseases related to Discitis

Symptoms & Phenotypes for Discitis

Drugs & Therapeutics for Discitis

Drugs for Discitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Anti-Bacterial Agents Phase 4
2 Antibiotics, Antitubercular Phase 4
3 Anti-Infective Agents Phase 4
4 Antitubercular Agents Phase 4
5 Vaccines
6 Fluorodeoxyglucose F18

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Comparison of Two Antimicrobial Therapy Duration for Spondylodiscitis Completed NCT00764114 Phase 4 antibiotic
2 Unilateral Posterolateral Approach for Spondylodiskitis Completed NCT03472131 Not Applicable
3 Molecular Microbiology in Osteo-arthritis Infection Completed NCT01193803
4 Cytokine Profiles in Spondylodiscitis Recruiting NCT02554227
5 Subclinical Propionibacterium Acnes Infection Estimation in the Intervertebral Disc (SPInE-ID) Recruiting NCT03158766
6 The European Robotic Spinal Instrumentation (EUROSPIN) Registry Recruiting NCT03398915
7 PDCN for Treatment of Cervical Vertigo Recruiting NCT03485768 Not Applicable
8 Complications Associated With Promontofixation for Pelvic Organ Prolapse: Comparing Robot Assisted Laparoscopic and Non-robot Assisted Laparoscopic Surgical Procedures Active, not recruiting NCT01320215 Not Applicable
9 CORset Versus OstéoSynthese in Adult Pyogenic Spondylodiscitis Not yet recruiting NCT03524209 Not Applicable
10 The Value of PET/CT in Diagnosing Residual Disease in Patients With Spinal Infection Suspended NCT01542853

Search NIH Clinical Center for Discitis

Cochrane evidence based reviews: discitis

Genetic Tests for Discitis

Anatomical Context for Discitis

MalaCards organs/tissues related to Discitis:

41
Bone, Testes, Liver

Publications for Discitis

Articles related to Discitis:

(show top 50) (show all 305)
# Title Authors Year
1
Treatment of lumbar discitis using silicon nitride spinal spacers: A case series and literature review. ( 29462728 )
2018
2
Discitis caused by rat bite fever in a rheumatoid arthritis patient on tocilizumab-first ever case. ( 29522179 )
2018
3
A successful antimicrobial therapeutic strategy for the discitis caused by Aggregatibacter actinomycetemcomitans under unknown drug susceptibility: A case report. ( 29685853 )
2018
4
Discitis in Adults. ( 29916943 )
2018
5
Recurrent discitis in the acute rehab setting: a case report. ( 29581890 )
2018
6
Lessons learned from a case of Candida Discitis. ( 28985261 )
2018
7
Discitis and Clostridium perfringens bacteraemia. ( 28747416 )
2017
8
Presence of Modic type 1 change increases risk of postoperative pyogenic discitis following decompression surgery for lumbar canal stenosis. ( 28802716 )
2017
9
Lumbar intravertebral disc herniation secondary to idiopathic calcific discitis. ( 29069932 )
2017
10
Paralysis Resulting from Calcific Discitis with Acute Herniation. ( 29067966 )
2017
11
[Retropharyngeal abscess with cervical discitis and vertebral osteomyelitis caused by Escherichia coli in a patient with liver cirrhosis]. ( 28603238 )
2017
12
Spontaneous Bilateral Sternoclavicular Joint Septic Arthritis and Lumbar Discitis: An Unusual Case in a Healthy Adult. ( 29130010 )
2017
13
The role of minimally invasive spine surgery in the management of pyogenic spinal discitis. ( 28250635 )
2017
14
Spontaneous Spinal Discitis and Spondylodiscitis: Clinicotherapeutic Remarks. ( 29204028 )
2017
15
Yield of Image-Guided Needle Biopsy for Infectious Discitis: A Systematic Review and Meta-Analysis. ( 28882866 )
2017
16
Calcific discitis with giant thoracic disc herniations in adults. ( 26821144 )
2016
17
Lumbosacral Osteomyelitis and Discitis with Phlegmon Following Laparoscopic Sacral Colpopexy. ( 27551651 )
2016
18
Correction: Lumbosacral Osteomyelitis and Discitis with Phlegmon Following Laparoscopic Sacral Colpopexy. ( 27766189 )
2016
19
Author Response: Management of Postoperative discitis. ( 27114786 )
2016
20
A novel rat tail discitis model using bioluminescent Staphylococcus aureus. ( 27918144 )
2016
21
Concurrent emphysematous pyelonephritis, cystitis, and iliopsoas abscess from discitis in a diabetic woman. ( 27637417 )
2016
22
Letter to the Editor: Management of Postoperative Discitis. ( 27114785 )
2016
23
Infectious Discitis and Spondylodiscitis in Children. ( 27070599 )
2016
24
Clinical case report: discitis osteomyelitis complicated by inferior vena cava venous thrombosis and septic pulmonary emboli. ( 27920864 )
2016
25
A case of epidemic myalgia with symptoms resembling acute purulent spondylitis and discitis. ( 27491355 )
2016
26
Clinical features of septic discitis in the UK: a retrospective case ascertainment study and review of management recommendations. ( 27417552 )
2016
27
Osteomyelitis, discitis, epidural and psoas abscess secondary to Salmonella enterica in a man with diabetes mellitus and newly diagnosed I+-thalassaemia trait. ( 25608980 )
2015
28
Cervical Discitis in Children. ( 25886786 )
2015
29
Traumatic discitis due to pharyngeal needle aspiration. ( 26377172 )
2015
30
Osteomyelitis and Discitis Following Translumbar Repair of a Type II Endoleak. ( 26493825 )
2015
31
Pathologic basis of pyogenic, nonpyogenic, and other spondylitis and discitis. ( 25952170 )
2015
32
Minimally invasive lateral transpsoas approach for spinal discitis and osteomyelitis. ( 26209920 )
2015
33
Acute symptomatic calcific discitis in adults: a case report and review of literature. ( 26160461 )
2015
34
Peptostreptococcus endocarditis presenting as lumbar discitis in an immunocompromised patient. ( 25437129 )
2015
35
Lumbosacral discitis following laparoscopic ventral mesh rectopexy: a rare but potentially serious complication. ( 25720459 )
2015
36
Postoperative initial single fungal discitis progressively spreading to adjacent multiple segments after lumbar discectomy. ( 25436471 )
2015
37
A Retrospective Analysis of the Management of Postoperative Discitis: A Single Institutional Experience. ( 26240715 )
2015
38
Biomechanical responses due to discitis infection of a juvenile thoracolumbar spine using finite element modeling. ( 24703867 )
2014
39
Antibiotic-impregnated polymethylmethacrylate as an anterior biomechanical device for the treatment of cervical discitis and vertebral osteomyelitis: technical report of two cases. ( 25050693 )
2014
40
Lumbosacral discitis-osteomyelitis after mesh abdominosacrocolpopexy. ( 25117721 )
2014
41
Posterior fixation without debridement for vertebral body osteomyelitis and discitis. ( 25081966 )
2014
42
Adalimumab for recurrent inflammatory discitis associated with spondyloarthropathy. ( 24824277 )
2014
43
Direct lateral retroperitoneal approach for the surgical treatment of lumbar discitis and osteomyelitis. ( 25081965 )
2014
44
Vertebral discitis after laparoscopic resection rectopexy: a rare differential diagnosis. ( 25084791 )
2014
45
Management of pyogenic discitis. ( 24967056 )
2014
46
Surgical management of pyogenic discitis of lumbar region. ( 24761200 )
2014
47
Lumbar discitis caused by Clostridium perfringens. ( 25056327 )
2014
48
Resolving back pain: a case of untreated discitis. ( 24855081 )
2014
49
Mycobacterium bovis vertebral osteomyelitis and discitis with adjacent mycotic abdominal aortic aneurysm caused by intravesical BCG therapy: a case report in an elderly gentleman. ( 23151379 )
2013
50
Virulence gene and expression analysis of community-associated methicillin-resistant Staphylococcus aureus causing iliopsoas abscess and discitis with thrombocytopenia. ( 23371452 )
2013

Variations for Discitis

Expression for Discitis

Search GEO for disease gene expression data for Discitis.

Pathways for Discitis

GO Terms for Discitis

Molecular functions related to Discitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 8.8 CALCA CRP MRI1

Sources for Discitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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