Aliases & Classifications for Discitis

MalaCards integrated aliases for Discitis:

Name: Discitis 12 44 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:10986
ICD10 33 M46.4
MeSH 44 D015299
SNOMED-CT 68 2304001
UMLS 73 C0012624

Summaries for Discitis

MalaCards based summary : Discitis is related to epidural abscess and spondyloarthropathy 1. An important gene associated with Discitis is CALCA (Calcitonin Related Polypeptide Alpha). The drugs Antitubercular Agents and Anti-Infective Agents have been mentioned in the context of this disorder. Affiliated tissues include bone, testes and liver.

Wikipedia : 76 Discitis or diskitis is an infection in the intervertebral disc space that affects different age groups.... more...

Related Diseases for Discitis

Diseases related to Discitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 67)
# Related Disease Score Top Affiliating Genes
1 epidural abscess 30.7 MRI1 CRP
2 spondyloarthropathy 1 30.3 MRAP CRP
3 osteomyelitis 10.7
4 endocarditis 10.4
5 spondylitis 10.4
6 arthritis 10.2
7 spondylolisthesis 10.1
8 sepsis in premature infants 10.1 CRP CALCA
9 suppurative thyroiditis 10.1 CRP CALCA
10 acute cholangitis 10.1 CRP CALCA
11 aortic aneurysm, familial abdominal, 1 10.1
12 rheumatoid arthritis 10.1
13 infective endocarditis 10.1
14 aortic aneurysm 10.1
15 septic arthritis 10.1
16 bacterial sepsis 10.0 CRP CALCA
17 aortitis 10.0 MRAP CRP
18 pyuria 10.0 MRAP CRP
19 tenosynovitis 10.0 MRAP CRP
20 bursitis 10.0 MRAP CRP
21 tendinitis 10.0 MRAP CRP
22 diffuse pulmonary fibrosis 10.0 MRAP CALCA
23 renal tuberculosis 10.0 MRAP CRP
24 mesenteric lymphadenitis 10.0 MRAP CRP
25 myeloma, multiple 10.0
26 crohn's disease 10.0
27 leukemia 10.0
28 meningitis 10.0
29 mycobacterium xenopi 10.0
30 palindromic rheumatism 10.0 MRAP CRP
31 purulent endophthalmitis 9.9 MRAP IVD
32 chronic kidney failure 9.9 CRP CALCA
33 bone inflammation disease 9.9 MRAP CRP
34 aortic valve disease 1 9.9 MRAP CRP
35 behcet syndrome 9.9 MRAP CRP
36 penile disease 9.9 MRAP MID2
37 tetralogy of fallot 9.9 CRP CALCA
38 medulloblastoma 9.8
39 pelvic organ prolapse 9.8
40 thrombophilia due to thrombin defect 9.8
41 lymphoma, hodgkin, classic 9.8
42 lymphoma, non-hodgkin, familial 9.8
43 psoriatic arthritis 9.8
44 leukemia, acute lymphoblastic 9.8
45 acute leukemia 9.8
46 diabetes mellitus 9.8
47 liver cirrhosis 9.8
48 thrombocytopenia 9.8
49 lymphoma 9.8
50 thrombosis 9.8

Graphical network of the top 20 diseases related to Discitis:



Diseases related to Discitis

Symptoms & Phenotypes for Discitis

Drugs & Therapeutics for Discitis

Drugs for Discitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 9)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Antitubercular Agents Phase 4,Not Applicable
2 Anti-Infective Agents Phase 4,Not Applicable
3 Antibiotics, Antitubercular Phase 4,Not Applicable
4 Anti-Bacterial Agents Phase 4,Not Applicable
5 Pharmaceutical Solutions Not Applicable
6 Vaccines
7 Anesthetics Not Applicable
8 Calamus Not Applicable
9 Fluorodeoxyglucose F18

Interventional clinical trials:

(show all 12)
# Name Status NCT ID Phase Drugs
1 Comparison of Two Antimicrobial Therapy Duration for Spondylodiscitis Completed NCT00764114 Phase 4 antibiotic
2 Unilateral Posterolateral Approach for Spondylodiskitis Completed NCT03472131 Not Applicable
3 Percutaneous Fluoroscopic vs CT Guided Core Needle Biopsy for Spinal Infection and Tumor Completed NCT03585699 Not Applicable
4 Molecular Microbiology in Osteo-arthritis Infection Completed NCT01193803
5 Cytokine Profiles in Spondylodiscitis Recruiting NCT02554227
6 Subclinical Propionibacterium Acnes Infection Estimation in the Intervertebral Disc (SPInE-ID) Recruiting NCT03158766
7 Laparoscopic Sacrocolpexy Versus Lateral Suspension Recruiting NCT03582852 Not Applicable
8 The European Robotic Spinal Instrumentation (EUROSPIN) Study Recruiting NCT03398915
9 PDCN for Treatment of Cervical Vertigo Recruiting NCT03485768 Not Applicable
10 CORset Versus OstéoSynthese in Adult Pyogenic Spondylodiscitis Active, not recruiting NCT03524209 Not Applicable
11 Complications Associated With Promontofixation for Pelvic Organ Prolapse: Comparing Robot Assisted Laparoscopic and Non-robot Assisted Laparoscopic Surgical Procedures Active, not recruiting NCT01320215 Not Applicable
12 The Value of PET/CT in Diagnosing Residual Disease in Patients With Spinal Infection Suspended NCT01542853

Search NIH Clinical Center for Discitis

Cochrane evidence based reviews: discitis

Genetic Tests for Discitis

Anatomical Context for Discitis

MalaCards organs/tissues related to Discitis:

41
Bone, Testes, Liver, Kidney, Thyroid

Publications for Discitis

Articles related to Discitis:

(show top 50) (show all 317)
# Title Authors Year
1
Treatment of lumbar discitis using silicon nitride spinal spacers: A case series and literature review. ( 29462728 )
2018
2
Discitis caused by rat bite fever in a rheumatoid arthritis patient on tocilizumab-first ever case. ( 29522179 )
2018
3
A successful antimicrobial therapeutic strategy for the discitis caused by Aggregatibacter actinomycetemcomitans under unknown drug susceptibility: A case report. ( 29685853 )
2018
4
Discitis in Adults. ( 29916943 )
2018
5
Recurrent discitis in the acute rehab setting: a case report. ( 29581890 )
2018
6
Infected abdominal aortic aneurysm graft complicated by lumbar discitis. ( 30363156 )
2018
7
Lessons learned from a case of Candida Discitis. ( 28985261 )
2018
8
Thoracic Discitis in Ankylosing Spondylitis. ( 30221099 )
2018
9
Management of Postoperative Discitis: A Review of 31 Patients. ( 30283531 )
2018
10
Transforaminal Interbody Debridement and Fusion to Manage Postdiscectomy Discitis in Lumbar Spine. ( 30308339 )
2018
11
Vertebral Osteomyelitis, Discitis, and Epidural Abscess: A Rare Complication of Cardiobacterium Endocarditis. ( 30397618 )
2018
12
Discitis and Clostridium perfringens bacteraemia. ( 28747416 )
2017
13
Presence of Modic type 1 change increases risk of postoperative pyogenic discitis following decompression surgery for lumbar canal stenosis. ( 28802716 )
2017
14
Lumbar intravertebral disc herniation secondary to idiopathic calcific discitis. ( 29069932 )
2017
15
Paralysis Resulting from Calcific Discitis with Acute Herniation. ( 29067966 )
2017
16
[Retropharyngeal abscess with cervical discitis and vertebral osteomyelitis caused by Escherichia coli in a patient with liver cirrhosis]. ( 28603238 )
2017
17
Spontaneous Bilateral Sternoclavicular Joint Septic Arthritis and Lumbar Discitis: An Unusual Case in a Healthy Adult. ( 29130010 )
2017
18
The role of minimally invasive spine surgery in the management of pyogenic spinal discitis. ( 28250635 )
2017
19
Spontaneous Spinal Discitis and Spondylodiscitis: Clinicotherapeutic Remarks. ( 29204028 )
2017
20
Yield of Image-Guided Needle Biopsy for Infectious Discitis: A Systematic Review and Meta-Analysis. ( 28882866 )
2017
21
Calcific discitis with giant thoracic disc herniations in adults. ( 26821144 )
2016
22
Lumbosacral Osteomyelitis and Discitis with Phlegmon Following Laparoscopic Sacral Colpopexy. ( 27551651 )
2016
23
Correction: Lumbosacral Osteomyelitis and Discitis with Phlegmon Following Laparoscopic Sacral Colpopexy. ( 27766189 )
2016
24
Author Response: Management of Postoperative discitis. ( 27114786 )
2016
25
A novel rat tail discitis model using bioluminescent Staphylococcus aureus. ( 27918144 )
2016
26
Concurrent emphysematous pyelonephritis, cystitis, and iliopsoas abscess from discitis in a diabetic woman. ( 27637417 )
2016
27
Letter to the Editor: Management of Postoperative Discitis. ( 27114785 )
2016
28
Infectious Discitis and Spondylodiscitis in Children. ( 27070599 )
2016
29
Clinical case report: discitis osteomyelitis complicated by inferior vena cava venous thrombosis and septic pulmonary emboli. ( 27920864 )
2016
30
A case of epidemic myalgia with symptoms resembling acute purulent spondylitis and discitis. ( 27491355 )
2016
31
Clinical features of septic discitis in the UK: a retrospective case ascertainment study and review of management recommendations. ( 27417552 )
2016
32
Diagnosis, Treatment, and Outcome of Stenotrophomonas maltophilia Discitis and Cervical Osteomyelitis: A Case Report and Review of the Literature. ( 29252617 )
2016
33
Osteomyelitis, discitis, epidural and psoas abscess secondary to Salmonella enterica in a man with diabetes mellitus and newly diagnosed I+-thalassaemia trait. ( 25608980 )
2015
34
Cervical Discitis in Children. ( 25886786 )
2015
35
Traumatic discitis due to pharyngeal needle aspiration. ( 26377172 )
2015
36
Osteomyelitis and Discitis Following Translumbar Repair of a Type II Endoleak. ( 26493825 )
2015
37
Pathologic basis of pyogenic, nonpyogenic, and other spondylitis and discitis. ( 25952170 )
2015
38
Minimally invasive lateral transpsoas approach for spinal discitis and osteomyelitis. ( 26209920 )
2015
39
Acute symptomatic calcific discitis in adults: a case report and review of literature. ( 26160461 )
2015
40
Peptostreptococcus endocarditis presenting as lumbar discitis in an immunocompromised patient. ( 25437129 )
2015
41
Lumbosacral discitis following laparoscopic ventral mesh rectopexy: a rare but potentially serious complication. ( 25720459 )
2015
42
Postoperative initial single fungal discitis progressively spreading to adjacent multiple segments after lumbar discectomy. ( 25436471 )
2015
43
A Retrospective Analysis of the Management of Postoperative Discitis: A Single Institutional Experience. ( 26240715 )
2015
44
Biomechanical responses due to discitis infection of a juvenile thoracolumbar spine using finite element modeling. ( 24703867 )
2014
45
Antibiotic-impregnated polymethylmethacrylate as an anterior biomechanical device for the treatment of cervical discitis and vertebral osteomyelitis: technical report of two cases. ( 25050693 )
2014
46
Lumbosacral discitis-osteomyelitis after mesh abdominosacrocolpopexy. ( 25117721 )
2014
47
Posterior fixation without debridement for vertebral body osteomyelitis and discitis. ( 25081966 )
2014
48
Answer to the topic "management of pyogenic discitis". ( 24967057 )
2014
49
Adalimumab for recurrent inflammatory discitis associated with spondyloarthropathy. ( 24824277 )
2014
50
Direct lateral retroperitoneal approach for the surgical treatment of lumbar discitis and osteomyelitis. ( 25081965 )
2014

Variations for Discitis

Expression for Discitis

Search GEO for disease gene expression data for Discitis.

Pathways for Discitis

GO Terms for Discitis

Molecular functions related to Discitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 8.92 CALCA CRP MRAP MRI1

Sources for Discitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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