Aliases & Classifications for Discitis

MalaCards integrated aliases for Discitis:

Name: Discitis 12 43 15 17 71

Classifications:



External Ids:

Disease Ontology 12 DOID:10986
MeSH 43 D015299
SNOMED-CT 67 2304001
ICD10 32 M46.4
UMLS 71 C0012624

Summaries for Discitis

MalaCards based summary : Discitis is related to epidural abscess and radiculopathy. An important gene associated with Discitis is CALCA (Calcitonin Related Polypeptide Alpha). The drugs Nabilone and Lidocaine have been mentioned in the context of this disorder. Affiliated tissues include bone, testes and prostate.

Wikipedia : 74 Discitis, or diskitis, is an infection in the intervertebral disc space that affects different age... more...

Related Diseases for Discitis

Diseases related to Discitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 176)
# Related Disease Score Top Affiliating Genes
1 epidural abscess 31.5 RPL34 CRP
2 radiculopathy 31.0 RPL34 ACAN
3 neurogenic arthropathy 30.6 CRP CALCA
4 septic arthritis 30.5 MRAP CRP CALCA
5 arachnoiditis 30.4 RPL34 CRP
6 sapho syndrome 30.3 MRAP CALCA
7 pustulosis of palm and sole 30.2 MRAP CRP
8 acute pyelonephritis 30.2 CRP CALCA
9 pyomyositis 30.1 TST CRP
10 spinal stenosis 30.1 RPL34 CALCA ACAN
11 spondylolysis 30.0 RPL34 FTH1
12 cauda equina syndrome 30.0 RPL34 MRAP CRP
13 exostosis 30.0 MRAP CALCA ACAN
14 bone inflammation disease 29.9 MRAP CRP ACAN
15 ankylosis 29.8 MRAP CRP
16 spondylolisthesis 29.8 RPL34 FTH1 CRP ACAN
17 spinal disease 29.6 RPL34 MRAP CRP ACAN
18 osteomyelitis 10.8
19 back pain 10.7
20 endocarditis 10.5
21 inflammatory spondylopathy 10.5
22 spondylitis 10.5
23 sepsis in premature infants 10.4 CRP CALCA
24 external ear carcinoma 10.4 CRP CALCA
25 subdural empyema 10.4 RPL34 CRP
26 acute cholangitis 10.4 CRP CALCA
27 spondyloarthropathy 1 10.4
28 infective endocarditis 10.4
29 raynaud disease 10.3 CRP CALCA
30 anterior scleritis 10.3 MRAP CRP
31 chronic pyelonephritis 10.3 CRP CALCA
32 scleritis 10.3 MRAP CRP
33 olecranon bursitis 10.3 MRAP CRP
34 bursitis 10.3 MRAP CRP
35 posterior scleritis 10.3 MRAP CRP
36 orbital plasma cell granuloma 10.3 MRAP CRP
37 mononeuropathy 10.3 RPL34 CRP
38 chronic orbital inflammation 10.3 MRAP CRP
39 erysipelas 10.3 CRP CALCA
40 neuroretinitis 10.3 MRAP CRP
41 decubitus ulcer 10.3 CRP CALCA
42 epididymo-orchitis 10.3 MRAP CRP
43 mesenteric lymphadenitis 10.3 MRAP CRP
44 optic papillitis 10.3 MRAP CRP
45 balanitis 10.3 MRAP CRP
46 aortitis 10.3 MRAP CRP
47 hypopyon 10.3 MRAP CRP
48 tenosynovitis 10.3 MRAP CRP
49 toxocariasis 10.3 MRAP CRP
50 scleral disease 10.3 MRAP CRP

Graphical network of the top 20 diseases related to Discitis:



Diseases related to Discitis

Symptoms & Phenotypes for Discitis

Drugs & Therapeutics for Discitis

Drugs for Discitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 14)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Nabilone Approved, Investigational 51022-71-0 5284592
2
Lidocaine Approved, Vet_approved 137-58-6 3676
3 Anti-Anxiety Agents
4 Psychotropic Drugs
5 Antiemetics
6 Gastrointestinal Agents
7 Pharmaceutical Solutions
8 Vaccines
9 Anti-Bacterial Agents
10 Antibiotics, Antitubercular
11 Anti-Infective Agents
12 Anesthetics
13 Anesthetics, Local
14 Fluorodeoxyglucose F18

Interventional clinical trials:

(show all 14)
# Name Status NCT ID Phase Drugs
1 Comparison of Two Antimicrobial Therapy Duration (6 Weeks Versus 12 Weeks)for Spondylodiscitis Completed NCT00764114 Phase 4 antibiotic
2 A Pilot Study to Evaluate the Safety and Effectiveness of Ozone Generated and Injected by the AO-1000 Device in the Treatment of Contained Herniated Discs Completed NCT01339377 Phase 1
3 Unilateral Posterolateral Approach for Disc Debridement and Titanium Cage Insertion Supplemented by Contralateral Transfascial Screw Fixation for Sick Patients Suffering From Septic Thoracolumbosacral Spondylodiscitis Completed NCT03472131
4 Spinal Infection Management With Structural Allograft Completed NCT03265561
5 Nabilone and THC/CBD for the Treatment of FBSS Refractory Pain Completed NCT03210766 Nabilone;THC/CBD
6 Verification and Progress of Cytokine Profiles and suPAR for the Discrimination of Infectious and Non-infectious, Degenerative Diseases of the Spine Completed NCT02554227
7 Accuracy, Safety and Diagnostic Outcome of Percutaneous Fluoroscopic vs. CT Guided Transpedicular Core Needle Biopsy for Spinal Infections and Tumors. A Prospective Randomized Trial Completed NCT03585699
8 Interest of Molecular Biology for Diagnostic of Osteo-arthritis Infections. EE Observational Prospective Study Completed NCT01193803
9 Comparison of Thoracolumbar Back Pain After Brace Treatment Versus Percutaneous Instrumentation in Adult Pyogenic Spondylodiscitis Combined With Antibiotic Treatment Recruiting NCT03524209
10 The European Robotic Spinal Instrumentation (EUROSPIN) Study: A European Prospective Multicenter Multinational Pragmatic Trial on Robot-guided Versus Navigated Versus Freehand Pedicle Screw Fixation Recruiting NCT03398915
11 Subclinical Propionibacterium Acnes Infection Estimation in the Intervertebral Disc (SPInE-ID): a Prospective Cohort Recruiting NCT03158766
12 The Effect of Intradermal Local Anesthetic Injection on Pain and Functionality in Failed Back Surgery Syndrome Not yet recruiting NCT04268602
13 Conservative Versus Surgical Treatment of Native Vertebral Osteomyelitis: a Randomized Multicentre Trial Not yet recruiting NCT04436328
14 Preliminary Study. The Value of 18F-FDG PET/CT Compared to MRI in Diagnosing Residual Disease in Patients With Spondylodiscitis Suspended NCT01542853

Search NIH Clinical Center for Discitis

Cochrane evidence based reviews: discitis

Genetic Tests for Discitis

Anatomical Context for Discitis

MalaCards organs/tissues related to Discitis:

40
Bone, Testes, Prostate, Spinal Cord, Bone Marrow, Eye, Heart

Publications for Discitis

Articles related to Discitis:

(show top 50) (show all 910)
# Title Authors PMID Year
1
[The Facet Wedge: a minimally invasive technique for posterior segmental intra-articular fusion]. 61
32179944 2020
2
Lumbosacral discitis as a rare complication of laparoscopic sacrocolpopexy. 61
32500164 2020
3
Pyogenic discitis with an epidural abscess after cervical analgesic discography: A case report. 61
32548162 2020
4
A unusual case of multifocal pyogenic abscess formation following ERCP procedure. 61
32375832 2020
5
Bacteroides Fragilis Vertebral Osteomyelitis and Discitis: "Back" to Susceptibility Testing. 61
32454579 2020
6
Subacute Presentation of Central Cord Syndrome Resulting from Vertebral Osteomyelitis and Discitis: A Case Report. 61
32426690 2020
7
Antibiotic-impregnated polymethylmethacrylate strut graft as a treatment of spinal osteomyelitis: case series and description of novel technique. 61
32384277 2020
8
Vague neck pain following a gastrointestinal procedure: a rare case presentation of vertebral osteomyelitis and cervical epidural abscess. 61
32404877 2020
9
Paediatric spondylodiscitis: a 10-year single institution experience in management and clinical outcomes. 61
31848723 2020
10
CT-guided discitis-osteomyelitis biopsies with negative microbiology: how many days should we wait before repeating the biopsy? 61
31760457 2020
11
CT-guided discitis-osteomyelitis biopsies: needle gauge and microbiology results. 61
32306072 2020
12
MRI and clinical features of acute fungal discitis/osteomyelitis. 61
31900707 2020
13
Development of machine learning and natural language processing algorithms for preoperative prediction and automated identification of intraoperative vascular injury in anterior lumbar spine surgery. 61
32294557 2020
14
Reduction of Radiation Dose and Scanning Time While Preserving Diagnostic Yield: A Comparison of Battery-Powered and Manual Bone Biopsy Systems. 61
32029464 2020
15
Bilateral End-Organ Endophthalmitis in Setting of Serratia marcescens Urosepsis on 18F-FDG PET/CT. 61
31876818 2020
16
Minimally Invasive Lateral Retropleural Approach to the Thoracic Spine for Salvage of a Subsided Expandable Interbody Cage. 61
31841720 2020
17
Moraxella catarrhalis discitis: the first reported case. 61
32141203 2020
18
Change in Bone CT Attenuation and C-Reactive Protein are Predictors of Bone Biopsy Culture Positivity in Patients with Vertebral Discitis/Osteomyelitis. 61
32205702 2020
19
Non-infectious thoracic discitis: A diagnostic and management dilemma. A report of two cases with review of the literature. 61
31931336 2020
20
A minimally invasive, 3D-fluoroscopy-navigation-guided, 3D-controlled pedicle approach in spine surgery: first reliable results and impact on patient safety. 61
32123950 2020
21
Early Experience, Setup, Learning Curve, Benefits, and Complications Associated with Exoscope and Three-Dimensional 4K Hybrid Digital Visualizations in Minimally Invasive Spine Surgery. 61
31608611 2020
22
Sensing Living Bacteria in Vivo Using d-Alanine-Derived 11C Radiotracers. 61
32123733 2020
23
Break up the band: Laparoscopic Adjustable Gastric Banding-associated Discitis and Osteomyelitis. 61
32064431 2020
24
Rare presentation of vertebral discitis, osteomyelitis and polyarticular septic arthritis due to disseminated Neisseria gonorrhea infection. 61
32128060 2020
25
Paraspinal Fat Stranding as an Unexpected Finding on Body Computed Tomography: A Key to Early Detection of Spinal Osteomyelitis. 61
32123620 2020
26
Polymicrobial community-acquired Acinetobacter baumannii and Burkholderia pseudomallei bacteremia: opportunistic infections with similar risk factors in northern Australia. 61
32509526 2020
27
Acute Symptomatic Calcific Discitis Mimicking a Septic Spondylodiscitis. 61
32231841 2020
28
Does bone scintigraphy show Modic changes associated with increased bone turnover? 61
32071952 2020
29
Trauma Induced Calcium Pyrophosphate Deposition Disease of the Lumbar Spine. 61
32095306 2020
30
Spondylodiscitis: experience of surgical management of complicated cases after failed antibiotic treatment. 61
32057290 2020
31
Adjacent Segment Infection after Lumbar Fusion: A Case Report and the Literature Review. 61
32395359 2020
32
Bacteria: back pain, leg pain and Modic sign-a surgical multicentre comparative study. 61
31576463 2019
33
Encephalitis as a complication of a spinal-esophageal fistula due to discitis. 61
31788277 2019
34
Lumbar intravertebral disc herniation secondary to idiopathic calcific discitis. 61
29069932 2019
35
The role of 18F-FDG PET/CT in early infectious discitis: a case report after a negative MRI. 61
31417664 2019
36
[Minimal invasive surgery-transforaminal lumbar interbody fusion combined with expanded pedicle screw through Mast Quadrant channel for the treatment of senile pyogenic discitis and vertebral osteomyelitis]. 61
32512966 2019
37
Minimally Invasive Cervical Pedicle Screw Placement With a Freehand Technique Through the Posterolateral Approach Using a Tubular Retractor: A Technical Note. 61
30726993 2019
38
Optimizing the safety of intradiscal platelet-rich plasma: an in vitro study with Cutibacterium acnes. 61
31587600 2019
39
Treatment considerations for cervical and cervicothoracic spondylodiscitis associated with esophageal fistula due to cancer history or accidental injury: a 9-patient case series. 61
31256278 2019
40
Evaluation of Challenges in Diagnosis of Spontaneous Subacute Pyogenic Spondylodiscitis in Immunocompetent Patients: Experiences from a Tertiary Care Center. 61
30966724 2019
41
Acute pseudogout lumbar discitis resembling acute pyelonephritis in an elderly woman. 61
31387154 2019
42
Prevertebral neck abscess with Salmonella sandiego: a case presentation and literature review. 61
31345833 2019
43
Postoperative Lumbar Pyogenic Spondylodiscitis: An Institutional Review. 61
31595125 2019
44
Acute Calcific Discitis or Symptomatic Calcified Schmorl's Node of the Upper Thoracic Spine in an Adult: A Case Report and Literature Review. 61
31497157 2019
45
Limited versus Aggressive Open Discectomy for a Single Level Lumbar Intervertebral Disc Prolapse. 61
31391431 2019
46
Disseminated Coccidioidomycosis to the Spine-Case Series and Review of Literature. 61
31284663 2019
47
Spinal involvement with calcium pyrophosphate deposition disease in an academic rheumatology center: A series of 37 patients. 61
30415946 2019
48
Endoscopic Treatment of Thoracic Discitis with Robotic Access: A Case Report Merging Two Cutting-Edge Technologies. 61
30872196 2019
49
Fluoroscopy-guided percutaneous needle aspiration of posterior epidural abscesses: a report of two cases. 61
32385258 2019
50
BCG-induced discitis and osteomyelitis in a patient with a history of bladder cancer. 61
31033722 2019

Variations for Discitis

Expression for Discitis

Search GEO for disease gene expression data for Discitis.

Pathways for Discitis

GO Terms for Discitis

Sources for Discitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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