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MCID: DSS008
MIFTS: 58

Disease of Mental Health

Categories: Mental diseases, Neuronal diseases
Genes Variations Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for Disease of Mental Health

About this section

MalaCards integrated aliases for Disease of Mental Health:

Name: Disease of Mental Health 12 15
Mental Disorders 43 71
Mental Health 42 17

Classifications:

MalaCards categories:
Anatomical: Mental diseases Neuronal diseases
See all MalaCards categories (disease lists)
ICD10: 32


External Ids:

Disease Ontology 12 DOID:150
MeSH 43 D001523
NCIt 49 C2893
SNOMED-CT 67 74732009
UMLS 71 C0004936
Sources

Summaries for Disease of Mental Health

About this section
MedlinePlus : 42 What is mental health? Mental health includes our emotional, psychological, and social well-being. It affects how we think, feel, and act as we cope with life. It also helps determine how we handle stress, relate to others, and make choices. Mental health is important at every stage of life, from childhood and adolescence through adulthood and aging. What are mental disorders? Mental disorders are serious conditions which can affect your thinking, mood, and behavior. They may be occasional or long-lasting. They can affect your ability to relate to others and function each day. Mental disorders are common; more than half of all Americans will be diagnosed with one at some time in their life. But there are treatments. People with mental disorders can get better, and many of them recover completely. Why is mental health important? Mental health is important because it can help you to Cope with the stresses of life Be physically healthy Have good relationships Make meaningful contributions to your community Work productively Realize your full potential Your mental health is also important because it can affect your physical health. For example, mental disorders can raise your risk for physical health problems such as stroke, type 2 diabetes, and heart disease. What can affect my mental health? There are many different factors that can affect your mental health, including Biological factors, such as genes or brain chemistry Life experiences, such as trauma or abuse Family history of mental health problems Your lifestyle, such as diet, physical activity, and substance use You can also affect your mental health by taking steps to improve it, such as doing meditation, using relaxation techniques, and practicing gratitude. Can my mental health change over time? Over time, your mental health can change. For example, you may be dealing with a difficult situation, such as trying to manage a chronic illness, taking care of an ill relative, or facing money problems. The situation may wear you out and overwhelm your ability to cope with it. This can worsen your mental health. On the other hand, getting therapy may improve your mental health. What are the signs that I might have a mental health problem? When it comes to your emotions, it can be hard to know what is normal and what is not. There are warning signs that you may have a mental health problem, including A change in your eating or sleeping habits Withdrawing from the people and activities you enjoy Having low or no energy Feeling numb or like nothing matters Having unexplained aches and pains Feeling helpless or hopeless Smoking, drinking, or using drugs more than usual Feeling unusually confused, forgetful, angry, upset, worried, or scared Having severe mood swings that cause problems in your relationships Having thoughts and memories that you can't get out of your head Hearing voices or believing things that are not true Thinking of harming yourself or others Not being able to perform daily tasks like taking care of your kids or getting to work or school What should I do if I think I have a mental health problem? If you think that you may have a mental health problem, get help. Talk therapy and/or medicines can treat mental disorders. If you don't know where to start, contact your primary care provider.

MalaCards based summary : Disease of Mental Health, also known as mental disorders, is related to bipolar disorder and post-traumatic stress disorder, and has symptoms including lethargy, agitation and forgetful. An important gene associated with Disease of Mental Health is BDNF-AS (BDNF Antisense RNA), and among its related pathways/superpathways is Alzheimers Disease. The drugs Morphine and Ropivacaine have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and heart, and related phenotype is integument.

Disease Ontology : 12 A disease that involves a psychological or behavioral pattern generally associated with subjective distress or disability that occurs in an individual, and which are not a part of normal development or culture.

Wikipedia : 74 Mental health is the level of psychological well-being or an absence of mental illness. It is the state... more...

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Related Diseases for Disease of Mental Health

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Diseases related to Disease of Mental Health via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 1103)
# Related Disease Score Top Affiliating Genes
1 bipolar disorder 34.0 SLC6A4 PRODH MIR132 KDM4C DRD2 BDNF
2 post-traumatic stress disorder 34.0 SLC6A4 DRD2 BDNF APOE
3 depression 33.9 SLC6A4 BDNF-AS BDNF
4 anxiety 33.9 SLC6A4 PRODH DRD2 BDNF APOE
5 obsessive-compulsive disorder 33.7 SLC6A4 DRD2 BDNF APOE
6 major depressive disorder 33.7 SLC6A4 MIR132 DRD2 BDNF APOE
7 pervasive developmental disorder 33.5 SLC6A4 SERPINA3 PRODH MIR9-1 MIR24-1 KDM4C
8 schizophrenia 33.5 SLC6A4 SERPINA3 PRODH MIR9-1 MIR132 DRD2
9 specific developmental disorder 33.5 SLC6A4 SERPINA3 PRODH MIR9-1 MIR24-1 KDM4C
10 schizoaffective disorder 33.4 SLC6A4 PRODH DRD2 BDNF
11 panic disorder 33.4 SLC6A4 MIR22 DRD2 BDNF
12 eating disorder 33.2 SLC6A4 DRD2 BDNF
13 substance abuse 33.2 SLC6A4 SERPINA3 PRODH H2AC18 DRD2 CCR6
14 fibromyalgia 33.1 SLC6A4 DRD2 BDNF
15 learning disability 33.1 PRODH H2AC18 BLOC1S1
16 sexual disorder 32.9 SLC6A4 SERPINA3 H2AC18 DRD2
17 trichotillomania 32.9 MIR24-1 KDM4C DRD2
18 sleep disorder 32.9 SLC6A4 DRD2 BDNF APOE
19 somatoform disorder 32.8 SLC6A4 H2AC18 BDNF
20 mental depression 32.8 SLC6A4 SERPINA3 PRODH MIR24-1 H2AC18 DRD2
21 mood disorder 32.8 SLC6A4 PRODH MIR9-1 MIR132 H2AC18 DRD2
22 personality disorder 32.8 SLC6A4 DRD2 BDNF
23 dementia, lewy body 32.8 SERPINA3 MIR132 BDNF APOE
24 psychotic disorder 32.7 SLC6A4 SERPINA3 PRODH MIR9-1 MIR24-1 MIR22
25 alcohol use disorder 32.7 SLC6A4 KDM4C H2AC18 DRD2 CCR6 BDNF
26 generalized anxiety disorder 32.5 SLC6A4 PRODH DRD2 BDNF
27 physical disorder 32.4 PRODH MIR9-1 MIR24-1 H2AC18 ERCC6 EPRS1
28 autism spectrum disorder 32.3 SLC6A4 PRODH MIR21 MIR132 DRD2 BDNF
29 traumatic brain injury 32.3 DRD2 BDNF APOE
30 social phobia 32.2 SLC6A4 SERPINA3 PRODH DRD2 BDNF
31 dysthymic disorder 32.2 SLC6A4 SERPINA3 PRODH BDNF
32 brain injury 32.1 DRD2 BDNF APOE
33 tobacco addiction 32.1 SLC6A4 SERPINA3 H2AC18 DRD2 BDNF
34 borderline personality disorder 32.1 SLC6A4 DRD2 BDNF
35 substance dependence 32.0 SLC6A4 SERPINA3 H2AC18 DRD2 BDNF
36 agoraphobia 31.9 SLC6A4 MIR22 BDNF
37 body mass index quantitative trait locus 11 31.9 SERPINA3 PRODH MIR22 MIR21 KDM4C H2AC18
38 drug dependence 31.7 SLC6A4 DRD2 BDNF
39 pulmonary disease, chronic obstructive 31.7 SLC6A4 SERPINA3 MIR21 H2AC18 EPRS1 CCR6
40 endogenous depression 31.6 SLC6A4 H2AC18 BDNF
41 fetal alcohol syndrome 31.5 MIR9-1 KDM4C H2AC18 BDNF
42 phobic disorder 31.5 SLC6A4 SERPINA3 PRODH DRD2 BDNF
43 migraine with or without aura 1 31.5 SLC6A4 H2AC18 DRD2 BDNF APOE
44 amyotrophic lateral sclerosis 1 31.5 SERPINA3 PRODH MIR9-1 MIR24-1 MIR22 MIR132
45 skin disease 31.4 SERPINA3 PRODH MIR21 H2AC18 ERCC6 CCR6
46 bulimia nervosa 31.4 SLC6A4 DRD2 BDNF
47 alzheimer disease 31.4 SLC6A4 SERPINA3 MIR22 MIR132 MIR124-1 DRD2
48 arteries, anomalies of 31.4 SERPINA3 MIR9-1 MIR24-1 MIR22 MIR21 MIR132
49 fetal alcohol spectrum disorder 31.4 MIR9-1 KDM4C H2AC18 BDNF
50 irritable bowel syndrome 31.4 SLC6A4 MIR24-1 BDNF

Graphical network of the top 20 diseases related to Disease of Mental Health:



Diseases related to Disease of Mental Health
Sources

Symptoms & Phenotypes for Disease of Mental Health

About this section

UMLS symptoms related to Disease of Mental Health:


lethargy, agitation, forgetful, decrease in appetite, symptoms, nervousness, feeling jittery, alexithymia, increased libido, numbness, psychiatric symptom, hallucinations, auditory, hallucinations, visual, numbness localized, feeling detached, feeling strange, feeling weightless, floating feeling, dejection emotional, depressed reaction, hallucinations, sensory, restless sleep, difficulty sleeping, excitability, depression aggravated, agitation mental, numb mouth, opiate withdrawal symptoms, clouded consciousness, trembling inside, sluggishness

MGI Mouse Phenotypes related to Disease of Mental Health:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 9.28 APOE BDNF DRD2 EPRS1 ERCC6 KDM4C
Sources

Drugs & Therapeutics for Disease of Mental Health

About this section

Drugs for Disease of Mental Health (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 697)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Morphine Approved, Investigational Phase 4 57-27-2 5288826
2
Ropivacaine Approved Phase 4 84057-95-4 71273 175805
3
Parathyroid hormone Approved, Investigational Phase 4 9002-64-6
4
Methimazole Approved Phase 4 60-56-0 1349907
5
Etomidate Approved Phase 4 33125-97-2 36339 667484
6
Oxcarbazepine Approved Phase 4 28721-07-5 34312
7
Nifedipine Approved Phase 4 21829-25-4 4485
8
Amlodipine Approved Phase 4 88150-42-9 2162
9
Atenolol Approved Phase 4 29122-68-7 2249
10
Ketorolac Approved Phase 4 66635-83-4, 74103-06-3 3826
11
Tocopherol Approved, Investigational Phase 4 1406-66-2, 54-28-4 14986
12
Amitriptyline Approved Phase 4 50-48-6 2160
13
Clozapine Approved Phase 4 5786-21-0 2818
14
Amisulpride Approved, Investigational Phase 4 53583-79-2, 71675-85-9 2159
15
Valproic acid Approved, Investigational Phase 4 99-66-1 3121
16
Carbon monoxide Approved, Investigational Phase 4 630-08-0 281
17
Dextroamphetamine Approved, Illicit Phase 4 51-64-9 5826
18
Asenapine Approved Phase 4 65576-45-6, 85650-56-2 3001386
19
Nicotinamide Approved, Investigational Phase 4 98-92-0 936
20
Bupropion Approved Phase 4 34911-55-2, 34841-39-9 444
21
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
22 Coconut Approved Phase 4
23
Ferrous succinate Approved Phase 4 10030-90-7
24
Cyproheptadine Approved Phase 4 129-03-3 2913
25
Iloperidone Approved Phase 4 133454-47-4 71360
26
Celecoxib Approved, Investigational Phase 4 169590-42-5 2662
27
Clonazepam Approved, Illicit Phase 4 1622-61-3 2802
28
Selegiline Approved, Investigational, Vet_approved Phase 4 14611-51-9 5195 26757
29
Perphenazine Approved Phase 4 58-39-9 4748
30
Cinnarizine Approved, Investigational Phase 4 298-57-7 1547484 2761
31
Diazepam Approved, Illicit, Investigational, Vet_approved Phase 4 439-14-5 3016
32
Pimozide Approved Phase 4 2062-78-4 16362
33
Eszopiclone Approved, Investigational Phase 4 138729-47-2 969472
34
Tiagabine Approved, Investigational Phase 4 115103-54-3 60648
35
Zinc sulfate Approved, Investigational Phase 4 7733-02-0
36
Glucosamine Approved, Investigational Phase 4 3416-24-8 439213
37
Phentermine Approved, Illicit Phase 4 122-09-8 4771
38
Zolpidem Approved Phase 4 82626-48-0 5732
39
Liraglutide Approved Phase 4 204656-20-2 44147092
40
Orlistat Approved, Investigational Phase 4 96829-58-2 3034010
41
Tamsulosin Approved, Investigational Phase 4 106133-20-4 129211
42
Pramlintide Approved, Investigational Phase 4 151126-32-8
43
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
44
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
45
Megestrol acetate Approved, Investigational, Vet_approved Phase 4 595-33-5 11683
46
Phenytoin Approved, Vet_approved Phase 4 57-41-0 1775
47
Hydromorphone Approved, Illicit Phase 4 466-99-9 5284570
48
Rosiglitazone Approved, Investigational Phase 4 122320-73-4 77999
49
Bupivacaine Approved, Investigational Phase 4 2180-92-9, 38396-39-3 2474
50
Spironolactone Approved Phase 4 52-01-7, 1952-01-7 5833

Interventional clinical trials:

(show top 50) (show all 6201)
# Name Status NCT ID Phase Drugs
1 Myoinositol for the Treatment of Ovarian and Psychiatric Disorder in PCOS Patients. Unknown status NCT01246310 Phase 4
2 Effect of Slow-release Melatonin (Circadin®) Therapy on Idiopathic REM Sleep Behavior Disorder: a Pilot Study Unknown status NCT02836743 Phase 4 Circadin;Placebo
3 Clinical Psychopharmacology Division Institute of Mental Health, Peking University Unknown status NCT03148535 Phase 4 Lithium Carbonate;lithium carbonate combined with SSRI antidepressant treatment
4 Tolerance and Effect of Antipsychotics in Children and Adolescents With Psychosis- An Investigator-initiated, Phase IV, Randomised Double-blind Multi-centre Trial of the Benefits and Harms of Aripiprazole Versus Quetiapine in Children and Adolescents With Psychosis Unknown status NCT01119014 Phase 4 Aripiprazole;Quetiapine
5 A Pilot Study to Determine if Pantoprazole Modifies Steady-State Plasma Concentrations of Orally Administered Psychotropic Medications Unknown status NCT02213887 Phase 4 Pantoprazole;Pantoprazole
6 Aggressive Behaviour in Children With Tourette's Syndrome (TS) and Comorbid Attention Deficit Hyperactivity Disorder (ADHD) Unknown status NCT00152750 Phase 4 APO-clonidine
7 Reduction of Cardiovascular Risk in Severe Mental Illness Prescribing and Using Better and More Appropriated Drugs Unknown status NCT01182012 Phase 4
8 A Pilot Study to Determine How Frequency of Administration Modifies Steady-State Plasma Concentrations of Orally Administered Clozapine Unknown status NCT02286206 Phase 4 Clozapine
9 Clinical Psychopharmacology Division Institute of Mental Health, Peking University Unknown status NCT03148509 Phase 4 risperidone;aripiprazole;bupropion
10 Effects of N-Acetyl-Cysteine on Oxidative Stress Biomarkers in Bipolar Patients With and Without Tobacco Use Disorder Unknown status NCT02252341 Phase 4
11 A Randomized Controlled Trial of Antidepressant Maintenance for Major Depression Following Mild Traumatic Brain Injury Unknown status NCT00162916 Phase 4 citalopram;Placebo
12 The Effect of a Community-based Long-acting Antipsychotic-treated Management Model on the Violence Risk of Patients With Schizophrenia: a 1-year, Open-label Randomized Controlled Study Unknown status NCT03080194 Phase 4 paliperidone palmitate;control group
13 Clinical Evaluation of Acupuncture Treatment for Negative Symptoms of Schizophrenia Unknown status NCT03802838 Phase 4 Amisulpride
14 Cardiopulmonary Capacity In Different Quartiles Ranges Of Reference For Serum Thyroid Stimulating Hormone (TSH): Sectional Evaluation And Effect Of The Use Of Methimazole In Elderly Population Unknown status NCT01849861 Phase 4 Methimazole
15 Group Mindfulness-Based Cognitive Therapy for the Treatment of Late-Life Depression and Anxiety Symptoms in Primary Care: A Randomized Controlled Trial Unknown status NCT02777905 Phase 4
16 Evaluation of the Efficacy of Repetitive Transcranial Magnetic Stimulation on Cognitive, Anxiety and Depressive Symptoms in Patients Diagnosed With Major Depressive Disorder Unknown status NCT02213016 Phase 4
17 Phase 4 Study of Vitamin D3 Supplementation for Outcomes in Patients With Unipolar Depression Unknown status NCT01390662 Phase 4
18 Determining the Efficacy and Tolerance of Quetiapine Extended Release (XR) for the Management of Psychotic Aggression or Agitation in Adult Acute Psychiatry Unknown status NCT00986167 Phase 4 Quetiapine XR
19 Hyperventilation and ECT Seizure Duration: Effects on Cerebral Oxygen Saturation, and Therapeutic Outcome With Comparisons Between Etomidate and Ketamine in Patients With Major Depressive Disorder Unknown status NCT02924090 Phase 4 Etomidate;Ketamine
20 Comparative Efficacy and Acceptability of Lithium, Valproate, Oxcarbazepine, Quetiapine, Olanzapine, and Ziprasidone in Bipolar I Disorder, Manic or Mixed Phase Unknown status NCT01893229 Phase 4 Lithium;Valproate;Oxcarbazepine;Quetiapine;Olanzapine;Ziprasidone
21 The Effect of Quetiapine XR in Depressive Patients Showing Aberrant N100 Amplitude Slope Unknown status NCT01357967 Phase 4 SSRI monotherapy;Seroquel XR adjunctive
22 Comparison of Cognitive Functions of Schizophrenic Patients Treated With Sertindole Versus Risperidone Unknown status NCT00480844 Phase 4 Sertindole;Risperidone
23 Metformin for Weight Control in Adolescents Taking Atypical Antipsychotics- Double Blind Placebo Controlled Study Unknown status NCT00845936 Phase 4 Metformin
24 Prospective, Interventional Multicentre Study on the Effect of Deepening of Sedation on Intra-abdominal Pressure Unknown status NCT02944292 Phase 4 Propofol
25 A Randomized Controlled Study of Nifecardia SRFC (Nifedipine) and Adalat OROS (Nifedipine) in the Treatment of Patients With Essential Hypertension Unknown status NCT00173667 Phase 4 Nifedipine 30 mg GITS
26 The Monitor of Serum Prolactin Level and Related Clinical Observations Among Individuals With Schizophrenia Spectrum Illnesses in a 3 Months Aripiprazole Trial Unknown status NCT00468533 Phase 4 Aripiprazole
27 Treatment With Escitalopram (Cipralex®) for Adolescents With Obsessive-Compulsive Disorder: Efficacy, Safety, and Changes in Executive Functions, Metacognition, and Regional Brain Activations. Unknown status NCT00708240 Phase 4 Escitalopram
28 Effect of Active Telephone Calls in the Compliance of Hypertensive Patients With Treatment: An Open and Randomized Clinical Trial Unknown status NCT00813722 Phase 4 amlodipine (calcium chanel blocker) and losartan (at1 antagonist);atenolol (beta blocker) and hydrochlorothiazide (diuretic)
29 Frailty and Cognitive Function Assessment of TAVI Patients (The Hungarian Frailty Score) - Observational, Prospective, Singe Center Study Unknown status NCT02650388 Phase 4
30 A Randomized, Double-Blind, Placebo-Controlled, Flexible-Dose Titration Study of Aptensio XR® in Children Ages 4 to Under 6 Years Diagnosed With Attention Deficit-Hyperactivity Disorder (ADHD) Unknown status NCT02683265 Phase 4 Aptensio XR;Placebo
31 Postoperative Pain Relief Following Total Hip Arthroplasty. A Comparison Between Intrathecal Morphine (IM) and Local Infiltration Analgesia (LIA) Unknown status NCT01281891 Phase 4 LIA;I/T morphine
32 MRI With a Lymph Node Specific Contrast Agent: an Alternative for CT-Scanning and Lymph Node Dissection in Patients With Prostate Cancer? Unknown status NCT00185029 Phase 4
33 Joining Forces: Integrating Psychotropic Medication Into the Care of People With Mental Disorders in a Prayer Camp in Ghana Completed NCT02593734 Phase 4 olanzapine;risperidone;amitryptaline;fluoxetine
34 Randomized Controlled Trial of a Community-based Early Psychiatric Intervention Strategy to Screen and Manage Depression in the Elderly Completed NCT00430404 Phase 4
35 A Randomised Controlled Trial on the Effectiveness of Screening and Brief Counselling for Elderly Patients With Psychological Problems in Primary Care. Completed NCT00283270 Phase 4
36 Phase IV Study of Effectiveness of Aripiprazole, Quetiapine, and Ziprasidone in the Treatment of First Episode of Non-affective Psychosis Individuals Included in the First Episode Psychosis Clinical Program II (PAFIP II): a 3-year Follow-up Completed NCT02526030 Phase 4 Aripiprazole;Quetiapine;Ziprasidone
37 Phase IV Study of the Effectiveness of Aripiprazole, Quetiapine, and Ziprasidone in the Treatment of First Episode of Non-affective Psychosis Individuals Included in the First Episode Psychosis Clinical Program II (PAFIP II) Completed NCT02305823 Phase 4 Aripiprazole;Quetiapine;Ziprasidone
38 Efficacy and Safety of Paliperidone ER in Patients With First Episode Psychosis: an Open-label, Prospective Multi-center Study Completed NCT01157585 Phase 4 paliperidone ER
39 Efficacy and Safety With Ziprasidone in the Treatment of First-episode Schizophrenia Spectrum Disorder: Multi-center Study Completed NCT01157559 Phase 4 Ziprasidone
40 Efficacy and Safety of Aripiprazole in Patients With First Episode Psychosis: an Open-label, Prospective Multi-center Study Completed NCT01026584 Phase 4 Aripiprazole
41 Evaluation of Growth, Sexual Maturation, and Prolactin-Related Adverse Events in the Pediatric Population Exposed to Atypical Antipsychotic Drugs Completed NCT01050582 Phase 4 Risperidone;Other atypical antipsychotic drugs
42 Combined Mirtazapine and Selective Serotonin Reuptake Inhibitor (SSRI) Treatment of Post-traumatic Stress Disorder (PTSD) Completed NCT01178671 Phase 4 Mirtazapine;Sertraline
43 Neurocognitive Effectiveness in Treatment of First-episode Non-affective Psychosis: a Randomized Comparison of Aripiprazole, Quetiapine and Ziprasidone Over 1 Year Completed NCT02534363 Phase 4 Aripiprazole;Quetiapine;Ziprasidone
44 Feasibility Trial of a Tailored Smoking Cessation App for People With Serious Mental Illness Completed NCT03069482 Phase 4 Nicotine patch;Nicotine lozenge
45 Post-marketing Clinical Study on PAXIL Tablet in Patients With Depression or Depressive Mood - A Study on Combination of PAXIL Tablet and Benzodiazepines Completed NCT00259883 Phase 4 paroxetine
46 The Cognitive Effects of Risperidone and Olanzapine Completed NCT00108368 Phase 4 Risperidone;Olanzapine
47 An Open-Label Study of Aripiprazole to Evaluate the Safety and Tolerability in Patients With Psychosis Associated With Parkinson's Disease Completed NCT00095810 Phase 4 aripiprazole
48 A Multi-Center Study to Examine The Clinical Effects of Cross Titration of Antipsychotics With Ziprasidone in Subjects With Schizophrenia or Schizoaffective Disorder Completed NCT00137020 Phase 4 ziprasidone
49 Antidepressant Treatment at an Inner City Asthma Clinic Completed NCT01324700 Phase 4 High severity group: Escitalopram;High severity group: Placebo;Low severity group: Escitalopram;Low severity group: Placebo
50 A Twelve-Week, Open, Randomized Trial Comparing Valproate to Lithium in Bipolar I Patients Suffering From a Manic Episode Completed NCT00264173 Phase 4 Valproate sodium

Search NIH Clinical Center for Disease of Mental Health

Cochrane evidence based reviews: mental disorders

Sources

Genetic Tests for Disease of Mental Health

About this section
Sources

Anatomical Context for Disease of Mental Health

About this section

MalaCards organs/tissues related to Disease of Mental Health:

40
Brain, Testes, Heart, Breast, Eye, Prostate, Lung
Sources

Publications for Disease of Mental Health

About this section

Articles related to Disease of Mental Health:

(show top 50) (show all 30001)
# Title Authors PMID Year
1
Biopsychopharmacosocial approach to assess impact of social distancing and isolation on mental health in older adults. 61 42
32378460 2020
2
Physical symptoms and mental health status in deep underground miners: A cross-sectional study. 42 61
32118742 2020
3
Trajectories and mental health-related predictors of perceived discrimination and stigma among homeless adults with mental illness. 42
32106225 2020
4
Mental health care in Pakistan boosted by the highest office. 61
31868627 2020
5
Experiences with using an idiographic assessment procedure in primary mental health care services for adolescents. 61
32427540 2020
6
A narrative study of mental health recovery: exploring unique, open-ended and collective processes. 61
32249712 2020
7
Mental health in conflict settings - Authors' reply. 61
31868624 2020
8
Mental health in conflict settings. 61
31868621 2020
9
Mental health in conflict settings. 61
31868622 2020
10
Mental health, pain, and risk of drug misuse: A nationwide cohort study. 61
32485544 2020
11
Parental consent: A potential barrier for underage teens' participation in an mHealth mental health intervention. 61
32528858 2020
12
Mental Health Professionals' Perceptions of Parenting by Service Users with Psychosis. 61
31925655 2020
13
Poverty and mental health among migrants: When is ingroup exposure more protective than social ties? 61
32518815 2020
14
Ableist Microaggressions and the Mental Health of Disabled Adults. 61
32306130 2020
15
Does in-prison physical and mental health impact recidivism? 61
32258357 2020
16
Human rights in countries of origin and the mental health of migrants to Canada. 61
32322655 2020
17
Young people's labour market patterns and later mental health: A sequence analysis exploring the role of region of origin for young people's labour market trajectories and mental health. 61
32548233 2020
18
Editorial overview: Sleep, mental health and psychopathology. 61
32475720 2020
19
Development of a measure of stigma towards occupational stress for mental health professionals. 61
31897577 2020
20
Mental health and experience of being bullied in 12-year-old children with overweight and obesity. 61
31821589 2020
21
Epidemiology of loneliness in a cohort of UK mental health community crisis service users. 61
31222412 2020
22
Longitudinal changes in trauma narratives over the first year and associations with coping and mental health. 61
32379602 2020
23
Reconsidering interactive resilience processes in mental health: Implications for child and youth services. 61
32058584 2020
24
Leadership that promotes successful implementation of community-based mental health interventions. 61
32176322 2020
25
Strengthening mental health services in Sierra Leone: perspectives from within the health system. 61
32384138 2020
26
Prenatal effects of maternal nutritional stress and mental health on the fetal movement profile. 61
32409928 2020
27
The impact of a mental health course elective on student pharmacist attitudes. 61
32540052 2020
28
Implementation of a Mental Health Task Force in a collegiate-based emergency medical services organization. 61
30946625 2020
29
Feeling safe with patient-controlled admissions: A grounded theory study of the mental health patients' experiences. 61
32220089 2020
30
Low back pain, mental health symptoms, and quality of life among injured service members. 61
32406726 2020
31
The use of social media by Australian preadolescents and its links with mental health. 61
32003901 2020
32
Impact of male-only lifestyle interventions on men's mental health: A systematic review and meta-analysis. 61
32181565 2020
33
Exploring college student identity among young people with foster care histories and mental health challenges. 61
32461707 2020
34
A systematic review on the effect of work-related stressors on mental health of young workers. 61
31932956 2020
35
Food insecurity and mental health: a systematic review and meta-analysis - CORRIGENDUM. 61
32364104 2020
36
Integration of a proactive, multidisciplinary mental health team on hospital medicine improves provider and nursing satisfaction. 61
32353568 2020
37
Middle and High School Student Perspectives on Digitally-Delivered Mental Health Assessments and Measurement Feedback Systems. 61
31938974 2020
38
Food insecurity and mental health: a systematic review and meta-analysis. 61
32174292 2020
39
The Experiences of Youth Mental Health Peer Workers over Time: A Qualitative Study with Longitudinal Analysis. 61
31970578 2020
40
Perceptions of Restrictiveness in Forensic Mental Health: Do Demographic, Clinical, and Legal Characteristics Matter? 61
31976788 2020
41
Mental Health Stigma: The Impact of Age and Gender on Attitudes. 61
32002711 2020
42
Medical Comorbidities and Medication Use Among Homeless Adults Seeking Mental Health Treatment. 61
31955290 2020
43
The rs6311 of serotonin receptor 2A (5-HT2A) gene is associated with alexithymia and mental health. 61
32553368 2020
44
Attachment to Parents and Peers and Adolescent Mental Health: The Mediating Role of Alexithymia. 61
31960177 2020
45
Perinatal mental health during the COVID-19 pandemic. 61
32418652 2020
46
Caution when linking COVID-19 to mental health consequences. 61
32387514 2020
47
Public Mental Health Crisis during COVID-19 Pandemic, China. 61
32202993 2020
48
Treating the mental health effects of COVID-19: The need for at-home neurotherapeutics is now. 61
32283246 2020
49
Addressing potential impact of COVID-19 pandemic on physical and mental health of elite athletes. 61
32387513 2020
50
Mental health consequences during the initial stage of the 2020 Coronavirus pandemic (COVID-19) in Spain. 61
32405150 2020
Sources

Variations for Disease of Mental Health

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ClinVar genetic disease variations for Disease of Mental Health:

6 ‎‎ ‎‎
# Gene Name Type Significance ClinVarId dbSNP ID GRCh37 Pos GRCh38 Pos
1 LOC730100 NC_000002.10:g.51151955_51190352del38398deletion no interpretation for the single variant 242471 2:51298451-51336848 2:51071313-51109710
2 LOC730100 NC_000002.10:g.51440969_51481281del40313deletion no interpretation for the single variant 242470 2:51587465-51627777 2:51360327-51400639
Sources

Expression for Disease of Mental Health

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Search GEO for disease gene expression data for Disease of Mental Health.
Sources

Pathways for Disease of Mental Health

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Pathways related to Disease of Mental Health according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Alzheimers Disease 1
11.19 MIR9-1 MIR21 MIR132 MIR124-1 APOE
Sources

GO Terms for Disease of Mental Health

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Cellular components related to Disease of Mental Health according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.56 SERPINA3 MIR24-1 MIR22 MIR21 MIR132 BLOC1S1
2 extracellular vesicle GO:1903561 8.92 MIR24-1 MIR22 MIR21 APOE

Biological processes related to Disease of Mental Health according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.8 SLC6A4 MIR21 MIR132 KDM4C ERCC6
2 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.67 MIR24-1 MIR21 DRD2 APOE
3 positive regulation of neuron differentiation GO:0045666 9.63 MIR124-1 KDM4C BDNF
4 response to toxic substance GO:0009636 9.61 SLC6A4 ERCC6 DRD2
5 negative regulation of blood vessel endothelial cell migration GO:0043537 9.43 MIR24-1 MIR132 APOE
6 gene silencing by miRNA GO:0035195 9.43 MIR9-1 MIR24-1 MIR22 MIR21 MIR132 MIR124-1
7 negative regulation of endothelial cell proliferation GO:0001937 9.33 MIR22 MIR21 APOE
8 positive regulation of vascular smooth muscle cell differentiation GO:1905065 9.32 MIR21 MIR124-1
9 miRNA mediated inhibition of translation GO:0035278 8.92 MIR9-1 MIR21 MIR132 MIR124-1

Molecular functions related to Disease of Mental Health according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mRNA binding involved in posttranscriptional gene silencing GO:1903231 9.1 MIR9-1 MIR24-1 MIR22 MIR21 MIR132 MIR124-1
Sources

Sources for Disease of Mental Health

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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