MCID: DSS001
MIFTS: 24

Disseminated Chorioretinitis

Categories: Neuronal diseases

Aliases & Classifications for Disseminated Chorioretinitis

MalaCards integrated aliases for Disseminated Chorioretinitis:

Name: Disseminated Chorioretinitis 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:8787
ICD9CM 34 363.1
SNOMED-CT 67 78769001
ICD10 32 H30.1
UMLS 71 C0154879

Summaries for Disseminated Chorioretinitis

MalaCards based summary : Disseminated Chorioretinitis is related to periostitis and periodontitis, chronic. An important gene associated with Disseminated Chorioretinitis is GNPTAB (N-Acetylglucosamine-1-Phosphate Transferase Subunits Alpha And Beta), and among its related pathways/superpathways are TRAF Pathway and RANK Signaling in Osteoclasts. Affiliated tissues include eye and retina, and related phenotypes are craniofacial and immune system

Related Diseases for Disseminated Chorioretinitis

Diseases related to Disseminated Chorioretinitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 38)
# Related Disease Score Top Affiliating Genes
1 periostitis 10.1 TNFRSF11B TNFRSF11A
2 periodontitis, chronic 10.1 TNFSF11 TNFRSF11B
3 multicentric reticulohistiocytosis 10.1 TNFSF11 TNFRSF11B
4 chronic apical periodontitis 10.1 TNFSF11 TNFRSF11B
5 craniometaphyseal dysplasia, autosomal dominant 10.0 TNFSF11 TNFRSF11B
6 aneurysmal bone cysts 10.0 TNFSF11 TNFRSF11A
7 giant cell reparative granuloma 10.0 TNFSF11 TNFRSF11A
8 glucocorticoid-induced osteoporosis 10.0 TNFSF11 TNFRSF11B
9 tooth resorption 10.0 TNFSF11 TNFRSF11A
10 osteopetrosis, autosomal recessive 7 10.0 TNFSF11 TNFRSF11A
11 renal osteodystrophy 10.0 TNFSF11 TNFRSF11B
12 ischemic bone disease 10.0 TNFSF11 TNFRSF11A
13 ankylosis 10.0 TNFSF11 TNFRSF11B
14 cellulitis 9.9 TNFSF11 GPT
15 fibrous dysplasia 9.9 TNFSF11 TNFRSF11A
16 osteonecrosis 9.9 TNFSF11 TNFRSF11B
17 histoplasmosis 9.9
18 chorioretinitis 9.9
19 polyarticular onset juvenile idiopathic arthritis 9.9 TNFSF11 TNFRSF11B TNFRSF11A
20 hemophilic arthropathy 9.9 TNFSF11 TNFRSF11B TNFRSF11A
21 arthropathy 9.8 TNFSF11 TNFRSF11B TNFRSF11A
22 paget disease of bone 5, juvenile-onset 9.8 TNFSF11 TNFRSF11B TNFRSF11A
23 multicentric carpotarsal osteolysis syndrome 9.8 TNFSF11 TNFRSF11B TNFRSF11A
24 root resorption 9.8 TNFSF11 TNFRSF11B TNFRSF11A
25 familial expansile osteolysis 9.8 TNFSF11 TNFRSF11B TNFRSF11A
26 benign giant cell tumor 9.8 TNFSF11 TNFRSF11B TNFRSF11A
27 mammary paget's disease 9.8 TNFSF11 TNFRSF11B TNFRSF11A
28 paget's disease of bone 9.8 TNFSF11 TNFRSF11B TNFRSF11A
29 bone resorption disease 9.8 TNFSF11 TNFRSF11B TNFRSF11A
30 bone remodeling disease 9.8 TNFSF11 TNFRSF11B TNFRSF11A
31 spondyloarthropathy 1 9.8 TNFSF11 TNFRSF11B
32 osteopetrosis 9.8 TNFSF11 TNFRSF11B TNFRSF11A
33 brittle bone disorder 9.8 TNFSF11 TNFRSF11B TNFRSF11A
34 far eastern spotted fever 9.8 SDHB GPT
35 bone disease 9.8 TNFSF11 TNFRSF11B TNFRSF11A
36 endosteal hyperostosis, autosomal dominant 9.7 TNFSF11 TNFRSF11B
37 myoglobinuria 9.7 SDHB GPT
38 scoliosis 9.6 TNFSF11 TNFRSF11B TNFRSF11A

Graphical network of the top 20 diseases related to Disseminated Chorioretinitis:



Diseases related to Disseminated Chorioretinitis

Symptoms & Phenotypes for Disseminated Chorioretinitis

MGI Mouse Phenotypes related to Disseminated Chorioretinitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 craniofacial MP:0005382 9.65 GNPTAB TGFBR3 TNFRSF11A TNFRSF11B TNFSF11
2 immune system MP:0005387 9.63 GNPTAB SDHB TGFBR3 TNFRSF11A TNFRSF11B TNFSF11
3 limbs/digits/tail MP:0005371 9.35 GNPTAB TGFBR3 TNFRSF11A TNFRSF11B TNFSF11
4 skeleton MP:0005390 9.1 GNPTAB GPT TGFBR3 TNFRSF11A TNFRSF11B TNFSF11

Drugs & Therapeutics for Disseminated Chorioretinitis

Search Clinical Trials , NIH Clinical Center for Disseminated Chorioretinitis

Genetic Tests for Disseminated Chorioretinitis

Anatomical Context for Disseminated Chorioretinitis

MalaCards organs/tissues related to Disseminated Chorioretinitis:

40
Eye, Retina

Publications for Disseminated Chorioretinitis

Articles related to Disseminated Chorioretinitis:

# Title Authors PMID Year
1
Choroidal Manifestation of Systemic Non-Tuberculous Mycobacterial Infection: A Case Series. 61
32219781 2020
2
Advantages and limitations of the spatially adaptive program SAPRO in clinical perimetry. 61
3755124 1986
3
Subacute sclerosing panencephalitis (SSPE). A case report. 61
7067595 1982
4
[Recurrent disseminated chorioretinitis due to acquired histoplasmosis (author's transl)]. 61
672116 1978

Variations for Disseminated Chorioretinitis

Expression for Disseminated Chorioretinitis

Search GEO for disease gene expression data for Disseminated Chorioretinitis.

Pathways for Disseminated Chorioretinitis

Pathways related to Disseminated Chorioretinitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.11 TNFSF11 TNFRSF11B TNFRSF11A
2
Show member pathways
11.94 TNFSF11 TNFRSF11B TNFRSF11A
3 11.54 TNFSF11 TNFRSF11B TNFRSF11A
4
Show member pathways
11.39 TNFSF11 A2M
5
Show member pathways
11.3 TNFSF11 TNFRSF11A
6
Show member pathways
11.25 TNFSF11 TNFRSF11B TNFRSF11A
7 10.79 TNFSF11 TNFRSF11B TNFRSF11A
8 10.47 TNFSF11 TNFRSF11B
9 10 TNFSF11 TNFRSF11B TNFRSF11A

GO Terms for Disseminated Chorioretinitis

Cellular components related to Disseminated Chorioretinitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.02 TNFSF11 TNFRSF11B TGFBR3 GPT A2M

Biological processes related to Disseminated Chorioretinitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 monocyte chemotaxis GO:0002548 9.43 TNFSF11 TNFRSF11A
2 tumor necrosis factor-mediated signaling pathway GO:0033209 9.43 TNFSF11 TNFRSF11B TNFRSF11A
3 osteoclast differentiation GO:0030316 9.4 TNFSF11 TNFRSF11A
4 positive regulation of bone resorption GO:0045780 9.37 TNFSF11 TNFRSF11A
5 mammary gland alveolus development GO:0060749 9.32 TNFSF11 TNFRSF11A
6 TNFSF11-mediated signaling pathway GO:0071847 9.16 TNFSF11 TNFRSF11A
7 positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling GO:0071848 8.96 TNFSF11 TNFRSF11A
8 positive regulation of fever generation by positive regulation of prostaglandin secretion GO:0071812 8.62 TNFSF11 TNFRSF11A

Sources for Disseminated Chorioretinitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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