Disseminated Chorioretinitis disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Disseminated Chorioretinitis

MalaCards integrated aliases for Disseminated Chorioretinitis:

Name: Disseminated Chorioretinitis ¹² ¹⁵ ⁷¹

Classifications:

MalaCards categories:
Anatomical: Eye diseases

See all MalaCards categories (disease lists)

ICD10: ³²

Diseases of the eye and adnexa

Disorders of choroid and retina

Chorioretinal inflammation

Disseminated chorioretinal inflammation

External Ids:

Disease Ontology ¹² DOID:8787

ICD9CM ³⁴ 363.1 363.10

SNOMED-CT ⁶⁷ 78769001

ICD10 ³² H30.1 H30.10

UMLS ⁷¹ C0154879

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Summaries for Disseminated Chorioretinitis

MalaCards based summary : Disseminated Chorioretinitis is related to chorioretinitis and birdshot chorioretinopathy. An important gene associated with Disseminated Chorioretinitis is GNPTAB (N-Acetylglucosamine-1-Phosphate Transferase Subunits Alpha And Beta), and among its related pathways/superpathways is Apoptosis and survival Anti-apoptotic TNFs/NF-kB/Bcl-2 pathway. Affiliated tissues include eye and retina, and related phenotypes are behavior/neurological and growth/size/body region

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Related Diseases for Disseminated Chorioretinitis

Diseases related to Disseminated Chorioretinitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 37)

#	Related Disease	Score	Top Affiliating Genes
1	chorioretinitis	29.4	TNFRSF1B MRAP
2	birdshot chorioretinopathy	10.5
3	posterior uveitis	10.5
4	non-infectious posterior uveitis	10.5
5	histoplasmosis	9.9
6	chronic endophthalmitis	9.8	MRAP CYP11B1
7	glaucomatocyclitic crisis	9.8	MRAP CYP11B1
8	fuchs' heterochromic uveitis	9.8	MRAP CYP11B1
9	scleromalacia perforans	9.8	TNFRSF1B MRAP
10	juvenile ankylosing spondylitis	9.8	TNFRSF1B MRAP
11	chronic orbital inflammation	9.8	TNFRSF1B MRAP
12	anterior scleritis	9.8	TNFRSF1B MRAP
13	scleritis	9.8	TNFRSF1B MRAP
14	optic papillitis	9.7	TNFRSF1B MRAP
15	aortitis	9.7	TNFRSF1B MRAP
16	hypopyon	9.7	TNFRSF1B MRAP
17	corneal dystrophy, band-shaped	9.7	TNFRSF1B MRAP
18	tenosynovitis	9.7	TNFRSF1B MRAP
19	pustulosis of palm and sole	9.7	TNFRSF1B MRAP
20	chondromalacia	9.7	TNFRSF1B MRAP
21	scleral disease	9.7	TNFRSF1B MRAP
22	bursitis	9.7	TNFRSF1B MRAP
23	iritis	9.7	TNFRSF1B MRAP
24	enthesopathy	9.7	TNFRSF1B MRAP
25	periostitis	9.7	TNFRSF11A MRAP
26	macular dystrophy, dominant cystoid	9.7	TNFRSF1B MRAP
27	tendinitis	9.6	TNFRSF1B MRAP
28	retinal vasculitis	9.6	TNFRSF1B MRAP
29	macular retinal edema	9.6	TNFRSF1B MRAP
30	panuveitis	9.6	TNFRSF1B MRAP
31	ankylosis	9.6	TNFRSF1B MRAP
32	hypersensitivity reaction type iv disease	9.6	TNFRSF1B MRAP
33	lipoid congenital adrenal hyperplasia	9.5	MRAP CYP11B1
34	uveal disease	9.5	TNFRSF1B MRAP
35	iridocyclitis	9.4	TNFRSF1B MRAP CYP11B1
36	spondyloarthropathy 1	9.4	TNFRSF1B MRAP
37	bone inflammation disease	9.2	TNFRSF1B MRAP

Graphical network of the top 20 diseases related to Disseminated Chorioretinitis:

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Symptoms & Phenotypes for Disseminated Chorioretinitis

MGI Mouse Phenotypes related to Disseminated Chorioretinitis:

⁴⁵

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	behavior/neurological	MP:0005386	9.88	CHL1 CYP11B1 GNPTAB MRAP TNFRSF11A TNFRSF1B
2	growth/size/body region	MP:0005378	9.73	CHL1 CYP11B1 GFER GNPTAB TNFRSF11A TNFRSF1B
3	endocrine/exocrine gland	MP:0005379	9.72	CYP11B1 GNPTAB MRAP TNFRSF11A TNFRSF1B
4	craniofacial	MP:0005382	9.67	CHL1 GNPTAB TNFRSF11A TNFRSF1B
5	homeostasis/metabolism	MP:0005376	9.63	CYP11B1 GFER GNPTAB MRAP TNFRSF11A TNFRSF1B
6	liver/biliary system	MP:0005370	9.26	GFER MRAP TNFRSF11A TNFRSF1B
7	respiratory system	MP:0005388	9.02	CHL1 GNPTAB MRAP TNFRSF11A TNFRSF1B

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Drugs & Therapeutics for Disseminated Chorioretinitis

Search Clinical Trials , NIH Clinical Center for Disseminated Chorioretinitis

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Genetic Tests for Disseminated Chorioretinitis

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Anatomical Context for Disseminated Chorioretinitis

MalaCards organs/tissues related to Disseminated Chorioretinitis:

⁴⁰

Eye, Retina

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Publications for Disseminated Chorioretinitis

Articles related to Disseminated Chorioretinitis:

#	Title	Authors	PMID	Year
1	Advantages and limitations of the spatially adaptive program SAPRO in clinical perimetry. ⁶¹	Fankhauser F...Kwasniewska S	3755124	1986
2	Subacute sclerosing panencephalitis (SSPE). A case report. ⁶¹	Brudet-Wickel CL...de Wolff-Rouendaal D	7067595	1982
3	[Recurrent disseminated chorioretinitis due to acquired histoplasmosis (author's transl)]. ⁶¹	Bernardczykowa A...Ziobrowski S	672116	1978

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Genes for Disseminated Chorioretinitis

Genes related to Disseminated Chorioretinitis (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	GNPTAB	N-Acetylglucosamine-1-Phosphate Transferase Subunits Alpha And Beta	Protein Coding	6.67	DISEASES inferred ¹⁵
2	GFER	Growth Factor, Augmenter Of Liver Regeneration	Protein Coding	5.21	DISEASES inferred ¹⁵
3	CYP11B1	Cytochrome P450 Family 11 Subfamily B Member 1	Protein Coding	4.92	DISEASES inferred ¹⁵
4	TNFRSF11A	TNF Receptor Superfamily Member 11a	Protein Coding	4.82	DISEASES inferred ¹⁵
5	CHL1	Cell Adhesion Molecule L1 Like	Protein Coding	4.53	DISEASES inferred ¹⁵
6	MRAP	Melanocortin 2 Receptor Accessory Protein	Protein Coding	3.76	DISEASES inferred ¹⁵
7	TNFRSF1B	TNF Receptor Superfamily Member 1B	Protein Coding	3.7	DISEASES inferred ¹⁵

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Variations for Disseminated Chorioretinitis

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Expression for Disseminated Chorioretinitis

Search GEO for disease gene expression data for Disseminated Chorioretinitis.

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Pathways for Disseminated Chorioretinitis

Pathways related to Disseminated Chorioretinitis according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Apoptosis and survival Anti-apoptotic TNFs/NF-kB/Bcl-2 pathway ²² Show member pathways Apoptosis and survival Anti-apoptotic TNFs/NF-kB/IAP pathway ²²	10.49	TNFRSF1B TNFRSF11A

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GO Terms for Disseminated Chorioretinitis

Biological processes related to Disseminated Chorioretinitis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	tumor necrosis factor-mediated signaling pathway	GO:0033209	8.62	TNFRSF1B TNFRSF11A

Molecular functions related to Disseminated Chorioretinitis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	tumor necrosis factor-activated receptor activity	GO:0005031	8.62	TNFRSF1B TNFRSF11A

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Sources for Disseminated Chorioretinitis

¹ BioSystems

² BitterDB

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⁴ Cell Signaling Technology

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⁶⁷ SNOMED-CT

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⁶⁹ TGDB

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⁷¹ UMLS

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⁷⁴ Wikipedia