MCID: DSS003
MIFTS: 27

Disseminated Eosinophilic Collagen Disease

Categories: Blood diseases

Aliases & Classifications for Disseminated Eosinophilic Collagen Disease

MalaCards integrated aliases for Disseminated Eosinophilic Collagen Disease:

Name: Disseminated Eosinophilic Collagen Disease 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:9499
SNOMED-CT 67 26328002
UMLS 71 C0263662

Summaries for Disseminated Eosinophilic Collagen Disease

MalaCards based summary : Disseminated Eosinophilic Collagen Disease is related to hypereosinophilic syndrome and collagen disease. An important gene associated with Disseminated Eosinophilic Collagen Disease is FIP1L1 (Factor Interacting With PAPOLA And CPSF1), and among its related pathways/superpathways are Akt Signaling and Cytokine Signaling in Immune system. Affiliated tissues include t cells, myeloid and b cells, and related phenotypes are Reduced mammosphere formation and hematopoietic system

Related Diseases for Disseminated Eosinophilic Collagen Disease

Diseases related to Disseminated Eosinophilic Collagen Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 94)
# Related Disease Score Top Affiliating Genes
1 hypereosinophilic syndrome 30.3 RNASE3 PDGFRA IL5RA IL5 IL3 IL2RA
2 collagen disease 10.5
3 pdgfra-associated chronic eosinophilic leukemia 10.4 PDGFRA FIP1L1
4 primary hypereosinophilic syndrome 10.4 PDGFRA FIP1L1
5 sm-ahnmd 10.3 PDGFRA FIP1L1 CHIC2
6 myeloid and lymphoid neoplasms associated with pdgfra rearrangement 10.3 PDGFRA FIP1L1 CHIC2
7 inflammatory bowel disease 4 10.2 RNASE3 EPX
8 loeffler syndrome 10.2 IL5 FIP1L1
9 b cell prolymphocytic leukemia 10.2 IL2RA CD5
10 autoimmune lymphoproliferative syndrome, type v 10.2 CD52 CD5
11 lymphoproliferative syndrome 1 10.2 IL2RA CD52
12 toxic oil syndrome 10.2 IL5 IL2RA
13 t-cell prolymphocytic leukemia 10.1 CD7 CD52
14 stevens-johnson syndrome/toxic epidermal necrolysis 10.1 IL5 CCL17
15 aggressive systemic mastocytosis 10.1 PDGFRA FIP1L1
16 parapsoriasis 10.1 CD7 CD5
17 vernal conjunctivitis 10.1 RNASE3 IL2RA EPX
18 systemic mastocytosis 10.0 PDGFRA IL2RA FIP1L1 CHIC2
19 eosinophilia-myalgia syndrome 10.0 RNASE2 IL5
20 cough variant asthma 10.0 RNASE3 IL5
21 pemphigoid gestationis 10.0 RNASE3 IL5
22 vernal keratoconjunctivitis 10.0 RNASE3 IL5
23 allergic bronchopulmonary aspergillosis 10.0 IL5 EPX CCL17
24 aspergillosis 10.0 IL5 EPX CCL17
25 elephantiasis 9.9 RNASE3 IL5
26 leukemia 9.9
27 peripheral nervous system disease 9.9
28 neuropathy 9.9
29 toxocariasis 9.9 RNASE3 IL5 FIP1L1
30 alzheimer disease 12 9.9 CD7 CD27
31 myeloid and lymphoid neoplasms associated with fgfr1 abnormalities 9.9 IL3 IL2RA
32 cutaneous t cell lymphoma 9.9 IL5 IL2RA CCL17
33 paragonimiasis 9.9 RNASE3 IL5 CCL17
34 conjunctivitis 9.9 RNASE3 IL5 EPX
35 chronic conjunctivitis 9.9 RNASE3 IL5
36 wells syndrome 9.9 RNASE3 IL5 IL2RA
37 echinococcosis 9.9 RNASE3 IL5 CCL17
38 chronic rhinitis 9.9 RNASE3 IL5 EPX
39 rhinitis 9.9 RNASE3 IL5 EPX
40 cow milk allergy 9.9 RNASE3 IL5
41 urinary schistosomiasis 9.9 RNASE3 IL5 EPX
42 onchocerciasis 9.8 RNASE3 IL5 EPX
43 bullous pemphigoid 9.8 RNASE3 IL5 CCL17
44 food allergy 9.8 RNASE3 IL5 EPX
45 eosinophilic gastritis 9.8 RNASE2 IL5 FIP1L1 EPX
46 b-cell expansion with nfkb and t-cell anergy 9.8 IL2RA CD5
47 kimura disease 9.8 RNASE3 IL5
48 mastocytosis, cutaneous 9.8 PDGFRA IL3 FIP1L1
49 t-cell adult acute lymphocytic leukemia 9.8 IL2RA CD7 CD52 CD5
50 prolymphocytic leukemia 9.7 IL2RA CD7 CD52 CD5

Graphical network of the top 20 diseases related to Disseminated Eosinophilic Collagen Disease:



Diseases related to Disseminated Eosinophilic Collagen Disease

Symptoms & Phenotypes for Disseminated Eosinophilic Collagen Disease

GenomeRNAi Phenotypes related to Disseminated Eosinophilic Collagen Disease according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Reduced mammosphere formation GR00396-S 9.17 CD27 CD5 CD52 CD7 IL2RA IL5

MGI Mouse Phenotypes related to Disseminated Eosinophilic Collagen Disease:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.65 CCL17 CD27 CD5 CD7 EHD1 EPX
2 immune system MP:0005387 9.28 CCL17 CD27 CD5 CD7 EPX IL2RA

Drugs & Therapeutics for Disseminated Eosinophilic Collagen Disease

Search Clinical Trials , NIH Clinical Center for Disseminated Eosinophilic Collagen Disease

Genetic Tests for Disseminated Eosinophilic Collagen Disease

Anatomical Context for Disseminated Eosinophilic Collagen Disease

MalaCards organs/tissues related to Disseminated Eosinophilic Collagen Disease:

40
T Cells, Myeloid, B Cells, Skin

Publications for Disseminated Eosinophilic Collagen Disease

Articles related to Disseminated Eosinophilic Collagen Disease:

(show all 16)
# Title Authors PMID Year
1
[Disseminated eosinophilic collagen disease]. 61
11212817 2000
2
[Disseminated eosinophilic collagen disease]. 61
9833449 1998
3
[Recurrent eosinophilic pneumonia. Bibliographical review, nosographic, pathogenetic and unitary setting reflections on the disease]. 61
3574733 1987
4
[Case of disseminated eosinophilic collagen disease with peripheral neuropathy and increase in the serum immune complexes]. 61
6327135 1983
5
Serum IgE and IgE antibody levels in patients with bronchial asthma, atopic dermatitis, eosinophilic granulomas of the soft tissue (Kimura's disease) and other diseases. 61
6600385 1983
6
[Dermal lesions in hematological diseases and their care - nursing of a patient with disseminated eosinophilic collagen disease]. 61
259119 1979
7
[A case of disseminated eosinophilic collagen disease (author's transl)]. 61
422899 1979
8
Hypereosinophilic multiple thrombosis. A proposal of a new designation of disseminated eosinophilic "collagen disease". 61
869293 1977
9
[Dry coughs and exertion-induced dyspnea (thoracic radiography and eosinophil count): (disseminated eosinophilic collagen disease)]. 61
611208 1977
10
[A case of disseminated eosinophilic collagen disease (author's transl)]. 61
1034750 1976
11
[A case of disseminated eosinophilic collagen disease (author's transl)]. 61
1240981 1975
12
Clinicopathologic conference: Disseminated eosinophilic collagen disease. 61
4812077 1974
13
[Eosinophilic leukemia or disseminated eosinophilic collagen disease? (apropos of severe nonparasitic eosinophilia)]. 61
5498872 1970
14
Disseminated eosinophilic collagen disease. 61
6023068 1967
15
EOSINOPHILIC LEUKEMIA AND DISSEMINATED EOSINOPHILIC COLLAGEN DISEASE--A DISEASE ENTITY? 61
14279494 1965
16
Disseminated eosinophilic collagen disease; a clinical and pathological study of a clinical entity related to Löffler's syndromes. 61
13301467 1956

Variations for Disseminated Eosinophilic Collagen Disease

Expression for Disseminated Eosinophilic Collagen Disease

Search GEO for disease gene expression data for Disseminated Eosinophilic Collagen Disease.

Pathways for Disseminated Eosinophilic Collagen Disease

Pathways related to Disseminated Eosinophilic Collagen Disease according to GeneCards Suite gene sharing:

(show all 17)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.15 PDGFRA IL5RA IL5 IL3 IL2RA CD27
2
Show member pathways
13.14 PDGFRA IL5RA IL5 IL3 IL2RA CD27
3
Show member pathways
13.01 PDGFRA IL5RA IL5 IL3 IL2RA CD27
4 12.6 PDGFRA IL5RA IL5 IL3 IL2RA
5
Show member pathways
12.37 RNASE3 PDGFRA IL5 IL3 IL2RA EPX
6
Show member pathways
12.25 PDGFRA IL5RA IL5 IL2RA
7
Show member pathways
12.05 PDGFRA IL5 IL3 IL2RA
8
Show member pathways
11.85 IL5RA IL5 IL3 IL2RA
9
Show member pathways
11.82 IL5RA IL5 IL2RA
10
Show member pathways
11.72 PDGFRA IL5RA IL5 IL3 IL2RA
11 11.69 IL5RA IL3 IL2RA
12 11.62 IL5 IL3 IL2RA CD5
13 11.59 IL5 IL2RA CD7
14
Show member pathways
11.55 IL5 IL3 IL2RA
15 11.27 IL5 IL2RA CCL17
16 11.1 IL5RA IL5 IL3 IL2RA CD7 CD5
17 11.02 IL5RA IL5 IL2RA

GO Terms for Disseminated Eosinophilic Collagen Disease

Cellular components related to Disseminated Eosinophilic Collagen Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.56 RNASE3 RNASE2 IL5 IL3 EPX CD52
2 external side of plasma membrane GO:0009897 9.02 PDGFRA IL5RA IL2RA CD5 CD27

Biological processes related to Disseminated Eosinophilic Collagen Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chemotaxis GO:0006935 9.58 RNASE2 PDGFRA CCL17
2 cytokine-mediated signaling pathway GO:0019221 9.56 IL5RA IL5 IL3 IL2RA
3 immune response GO:0006955 9.55 IL5 IL3 IL2RA CD7 CCL17
4 RNA catabolic process GO:0006401 9.43 RNASE3 RNASE2
5 positive regulation of T cell differentiation GO:0045582 9.37 IL2RA CD27
6 inflammatory response to antigenic stimulus GO:0002437 9.32 IL5RA IL2RA
7 MAPK cascade GO:0000165 9.02 PDGFRA IL5RA IL5 IL3 IL2RA
8 induction of bacterial agglutination GO:0043152 8.96 RNASE3 RNASE2

Sources for Disseminated Eosinophilic Collagen Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....