MCID: DSS003
MIFTS: 25

Disseminated Eosinophilic Collagen Disease

Categories: Blood diseases

Aliases & Classifications for Disseminated Eosinophilic Collagen Disease

MalaCards integrated aliases for Disseminated Eosinophilic Collagen Disease:

Name: Disseminated Eosinophilic Collagen Disease 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:9499
SNOMED-CT 67 423486005
UMLS 71 C0263662

Summaries for Disseminated Eosinophilic Collagen Disease

MalaCards based summary : Disseminated Eosinophilic Collagen Disease is related to hypereosinophilic syndrome and collagen disease. An important gene associated with Disseminated Eosinophilic Collagen Disease is FIP1L1 (Factor Interacting With PAPOLA And CPSF1), and among its related pathways/superpathways are Innate Immune System and PEDF Induced Signaling. Related phenotypes are Reduced mammosphere formation and hematopoietic system

Related Diseases for Disseminated Eosinophilic Collagen Disease

Diseases related to Disseminated Eosinophilic Collagen Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 112)
# Related Disease Score Top Affiliating Genes
1 hypereosinophilic syndrome 30.1 RNASE3 PDGFRA IL5RA IL5 IL3 IL2RA
2 collagen disease 10.5
3 pdgfra-associated chronic eosinophilic leukemia 10.5 PDGFRA FIP1L1
4 primary hypereosinophilic syndrome 10.4 PDGFRA FIP1L1
5 myeloid and lymphoid neoplasms associated with pdgfra rearrangement 10.3 PDGFRA FIP1L1 CHIC2
6 sm-ahnmd 10.3 PDGFRA FIP1L1 CHIC2
7 loeffler syndrome 10.3 IL5 FIP1L1
8 inflammatory bowel disease 4 10.3 RNASE3 EPX
9 toxic oil syndrome 10.2 IL5 IL2RA
10 b cell prolymphocytic leukemia 10.2 IL2RA CD5
11 stevens-johnson syndrome/toxic epidermal necrolysis 10.2 IL5 CCL17
12 vernal conjunctivitis 10.2 RNASE3 IL2RA EPX
13 autoimmune lymphoproliferative syndrome, type v 10.2 CD52 CD5
14 lymphoproliferative syndrome 1 10.2 IL2RA CD52
15 eosinophilia-myalgia syndrome 10.2 RNASE2 IL5 FIP1L1
16 cough variant asthma 10.1 RNASE3 IL5
17 allergic bronchopulmonary aspergillosis 10.1 IL5 EPX CCL17
18 aspergillosis 10.1 IL5 EPX CCL17
19 vernal keratoconjunctivitis 10.1 RNASE3 IL5
20 pemphigoid gestationis 10.1 RNASE3 IL5
21 toxocariasis 10.1 RNASE3 IL5 FIP1L1
22 red cell aplasia 10.1 IL2RA IFNA1
23 paragonimiasis 10.1 RNASE3 IL5 CCL17
24 vasomotor rhinitis 10.1 RNASE3 IL5
25 conjunctivitis 10.1 RNASE3 IL5 EPX
26 wells syndrome 10.1 RNASE3 IL5 IL2RA
27 chronic rhinitis 10.1 RNASE3 IL5 EPX
28 rhinitis 10.0 RNASE3 IL5 EPX
29 echinococcosis 10.0 RNASE3 IL5 CCL17
30 aggressive systemic mastocytosis 10.0 PDGFRA IFNA1 FIP1L1
31 urinary schistosomiasis 10.0 RNASE3 IL5 EPX
32 schistosomiasis 10.0 RNASE3 IL5 EPX
33 parapsoriasis 10.0 CD7 CD5
34 onchocerciasis 10.0 RNASE3 IL5 EPX
35 elephantiasis 10.0 RNASE3 IL5
36 cryoglobulinemia, familial mixed 10.0 IFNA1 CD5
37 eosinophilic gastritis 10.0 RNASE2 IL5 FIP1L1 EPX
38 bullous pemphigoid 10.0 RNASE3 IL5 CCL17
39 food allergy 10.0 RNASE3 IL5 EPX
40 autoimmune disease of blood 10.0 IL5 CD52 CD5
41 leukemia 9.9
42 peripheral nervous system disease 9.9
43 neuropathy 9.9
44 t-cell adult acute lymphocytic leukemia 9.9 CD7 CD52 CD5
45 myeloid and lymphoid neoplasms associated with fgfr1 abnormalities 9.9 IL3 IL2RA
46 bell's palsy 9.9 IL2RA IFNA1
47 chronic mucocutaneous candidiasis 9.8 IL5 IL2RA IFNA1
48 allergic rhinitis 9.8 RNASE3 IL5 EPX CCL17
49 conjunctival disease 9.8 RNASE3 IL5 IFNA1
50 aggressive nk-cell leukemia 9.8 CD7 CD5

Graphical network of the top 20 diseases related to Disseminated Eosinophilic Collagen Disease:



Diseases related to Disseminated Eosinophilic Collagen Disease

Symptoms & Phenotypes for Disseminated Eosinophilic Collagen Disease

GenomeRNAi Phenotypes related to Disseminated Eosinophilic Collagen Disease according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Reduced mammosphere formation GR00396-S 9.17 CD27 CD5 CD52 CD7 IL2RA IL5

MGI Mouse Phenotypes related to Disseminated Eosinophilic Collagen Disease:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.73 CCL17 CD27 CD5 CD7 CHIC2 EHD1
2 immune system MP:0005387 9.36 CCL17 CD27 CD5 CD7 CHIC2 EPX

Drugs & Therapeutics for Disseminated Eosinophilic Collagen Disease

Search Clinical Trials , NIH Clinical Center for Disseminated Eosinophilic Collagen Disease

Genetic Tests for Disseminated Eosinophilic Collagen Disease

Anatomical Context for Disseminated Eosinophilic Collagen Disease

Publications for Disseminated Eosinophilic Collagen Disease

Articles related to Disseminated Eosinophilic Collagen Disease:

(show all 16)
# Title Authors PMID Year
1
[Disseminated eosinophilic collagen disease]. 61
11212817 2000
2
[Disseminated eosinophilic collagen disease]. 61
9833449 1998
3
[Recurrent eosinophilic pneumonia. Bibliographical review, nosographic, pathogenetic and unitary setting reflections on the disease]. 61
3574733 1987
4
[Case of disseminated eosinophilic collagen disease with peripheral neuropathy and increase in the serum immune complexes]. 61
6327135 1983
5
Serum IgE and IgE antibody levels in patients with bronchial asthma, atopic dermatitis, eosinophilic granulomas of the soft tissue (Kimura's disease) and other diseases. 61
6600385 1983
6
[Dermal lesions in hematological diseases and their care - nursing of a patient with disseminated eosinophilic collagen disease]. 61
259119 1979
7
[A case of disseminated eosinophilic collagen disease (author's transl)]. 61
422899 1979
8
Hypereosinophilic multiple thrombosis. A proposal of a new designation of disseminated eosinophilic "collagen disease". 61
869293 1977
9
[Dry coughs and exertion-induced dyspnea (thoracic radiography and eosinophil count): (disseminated eosinophilic collagen disease)]. 61
611208 1977
10
[A case of disseminated eosinophilic collagen disease (author's transl)]. 61
1034750 1976
11
[A case of disseminated eosinophilic collagen disease (author's transl)]. 61
1240981 1975
12
Clinicopathologic conference: Disseminated eosinophilic collagen disease. 61
4812077 1974
13
[Eosinophilic leukemia or disseminated eosinophilic collagen disease? (apropos of severe nonparasitic eosinophilia)]. 61
5498872 1970
14
Disseminated eosinophilic collagen disease. 61
6023068 1967
15
EOSINOPHILIC LEUKEMIA AND DISSEMINATED EOSINOPHILIC COLLAGEN DISEASE--A DISEASE ENTITY? 61
14279494 1965
16
Disseminated eosinophilic collagen disease; a clinical and pathological study of a clinical entity related to Löffler's syndromes. 61
13301467 1956

Variations for Disseminated Eosinophilic Collagen Disease

Expression for Disseminated Eosinophilic Collagen Disease

Search GEO for disease gene expression data for Disseminated Eosinophilic Collagen Disease.

Pathways for Disseminated Eosinophilic Collagen Disease

Pathways related to Disseminated Eosinophilic Collagen Disease according to GeneCards Suite gene sharing:

(show all 19)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.86 RNASE3 RNASE2 PDGFRA IL5RA IL5 IL3
2
Show member pathways
13.5 PDGFRA IL5RA IL5 IL3 IL2RA IFNA1
3
Show member pathways
13.23 PDGFRA IL5RA IL5 IL3 IL2RA CD27
4
Show member pathways
13.15 PDGFRA IL5RA IL5 IL3 IL2RA IFNA1
5
Show member pathways
13.14 IL5RA IL5 IL3 IL2RA IFNA1 EHD1
6
Show member pathways
13.09 PDGFRA IL5RA IL5 IL3 IL2RA CD27
7 12.46 PDGFRA IL5RA IL5 IL3 IL2RA IFNA1
8
Show member pathways
12.27 PDGFRA IL5RA IL5 IL2RA
9
Show member pathways
12.24 RNASE3 PDGFRA IL5 IL3 IL2RA IFNA1
10
Show member pathways
12.03 PDGFRA IL5RA IL5 IL3 IL2RA IFNA1
11
Show member pathways
12.01 PDGFRA IL5 IL3 IL2RA IFNA1
12
Show member pathways
11.92 IL5RA IL5 IL3 IL2RA
13
Show member pathways
11.85 IL5RA IL5 IL2RA
14 11.69 IL5 IL3 IL2RA CD5
15 11.6 IL5 IL2RA CD7
16
Show member pathways
11.57 IL5 IL3 IL2RA
17 11.3 IL5 IL2RA CCL17
18 11.1 IL5RA IL5 IL3 IL2RA CD7 CD5
19 11.06 IL5RA IL5 IL2RA

GO Terms for Disseminated Eosinophilic Collagen Disease

Cellular components related to Disseminated Eosinophilic Collagen Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.76 RNASE3 IL5RA IL5 IL3 IFNA1 FCGRT
2 extracellular region GO:0005576 9.61 RNASE3 RNASE2 IL5 IL3 IFNA1 EPX
3 external side of plasma membrane GO:0009897 9.1 PDGFRA IL5RA IL2RA FCGRT CD5 CD27

Biological processes related to Disseminated Eosinophilic Collagen Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.55 IL5RA IL5 IL3 IL2RA IFNA1
2 MAPK cascade GO:0000165 9.35 PDGFRA IL5RA IL5 IL3 IL2RA
3 positive regulation of T cell differentiation GO:0045582 9.32 IL2RA CD27
4 induction of bacterial agglutination GO:0043152 9.26 RNASE3 RNASE2
5 immune response GO:0006955 9.1 IL5 IL3 IL2RA FCGRT CD7 CCL17

Molecular functions related to Disseminated Eosinophilic Collagen Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 8.92 IL5 IL3 IFNA1 CCL17

Sources for Disseminated Eosinophilic Collagen Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....