MCID: DSS025
MIFTS: 32

Dissociative Seizures

Categories: Mental diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Dissociative Seizures

MalaCards integrated aliases for Dissociative Seizures:

Name: Dissociative Seizures 54
Psychogenic Nonepileptic Seizures 54
Non-Epileptic Attack Disorder 54
Dissociative Convulsions 74
Psychogenic Seizures 54
Functional Seizures 54
Psychogenic Seizure 74
Pseudoseizures 54
Pnes 54

Classifications:



External Ids:

ICD10 34 F44.5

Summaries for Dissociative Seizures

NIH Rare Diseases : 54 Dissociative or psychogenic nonepileptic seizures(PNES) are involuntary episodes of movement, sensation, or behaviors (vocalizations, crying, and other expressions of emotion) that do not result from abnormal brain discharges. The seizures can look like any kind of epileptic seizure.  They are somatic manifestations (physical symptoms) of psychologic distress. Psychiatric conditions associated with PNES include depression, anxiety, somatoform disorder, posttraumatic stress disorder, dissociative disorder, and personality disorders. Treatment depends on the cause of the psychologic distress, and may involve cognitive behavioral therapy or psychotherapy, as well as antidepressive medication.

MalaCards based summary : Dissociative Seizures, also known as psychogenic nonepileptic seizures, is related to ewing sarcoma and diffuse idiopathic pulmonary neuroendocrine cell hyperplasia, and has symptoms including seizures The drugs Sertraline and Antidepressive Agents have been mentioned in the context of this disorder. Affiliated tissues include brain, temporal lobe and heart.

Wikipedia : 77 Psychogenic non-epileptic seizures (PNES) are events resembling an epileptic seizure, but without the... more...

Related Diseases for Dissociative Seizures

Diseases related to Dissociative Seizures via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 47)
# Related Disease Score Top Affiliating Genes
1 ewing sarcoma 11.1
2 diffuse idiopathic pulmonary neuroendocrine cell hyperplasia 11.1
3 pudendal neuralgia 11.1
4 neuronal migration disorders 10.7
5 alexithymia 10.5
6 movement disease 10.5
7 syncope 10.4
8 temporal lobe epilepsy 10.3
9 stuttering 10.3
10 personality disorder 10.3
11 status epilepticus 10.3
12 seizure disorder 10.2
13 conversion disorder 10.2
14 migraine with or without aura 1 10.2
15 autism 10.2
16 intraocular pressure quantitative trait locus 10.2
17 alacrima, achalasia, and mental retardation syndrome 10.2
18 brain injury 10.2
19 traumatic brain injury 10.2
20 autism spectrum disorder 10.2
21 aphasia 10.2
22 amnestic disorder 10.2
23 borderline personality disorder 10.2
24 disease of mental health 10.2
25 focal epilepsy 10.2
26 pain - chronic 10.2
27 encephalopathy 10.2
28 head injury 10.2
29 dissociative disorder 10.1
30 pelizaeus-merzbacher disease 10.0
31 spinal cord injury 10.0
32 post-traumatic stress disorder 10.0
33 depression 10.0
34 psychogenic movement 10.0
35 dandy-walker syndrome 10.0
36 hydrocephalus 10.0
37 multiple personality disorder 10.0
38 ischemia 10.0
39 learning disability 10.0
40 narcolepsy 10.0
41 congenital hydrocephalus 10.0
42 serotonin syndrome 10.0
43 epilepsy, idiopathic generalized 10 9.9
44 complex partial epilepsy 9.9
45 anxiety 9.8
46 epilepsy 9.8
47 early myoclonic encephalopathy 9.8

Graphical network of the top 20 diseases related to Dissociative Seizures:



Diseases related to Dissociative Seizures

Symptoms & Phenotypes for Dissociative Seizures

UMLS symptoms related to Dissociative Seizures:


seizures

Drugs & Therapeutics for Dissociative Seizures

Drugs for Dissociative Seizures (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 13)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Sertraline Approved Phase 4 79617-96-2 68617
2 Antidepressive Agents Phase 4
3 Serotonin Agents Phase 4
4 Psychotropic Drugs Phase 4
5 Serotonin Uptake Inhibitors Phase 4
6 Neurotransmitter Agents Phase 4,Not Applicable
7 Neurotransmitter Uptake Inhibitors Phase 4
8
Serotonin Investigational, Nutraceutical Phase 4 50-67-9 5202
9
Caffeine Approved Not Applicable 58-08-2 2519
10 Convulsants Not Applicable
11 Phosphodiesterase Inhibitors Not Applicable
12 Central Nervous System Stimulants Not Applicable
13 Purinergic P1 Receptor Antagonists Not Applicable

Interventional clinical trials:

(show all 19)
# Name Status NCT ID Phase Drugs
1 Treatments for Psychogenic Nonepileptic Seizures (NES) Completed NCT00159965 Phase 4 sertraline;placebo
2 Treatment Trial for Psychogenic Nonepileptic Seizures Completed NCT00835627 Phase 4 sertraline
3 Quality of Life and Psychogenic Nonepileptic Seizures. Unknown status NCT02821208
4 Cognitive Behavioural Therapy in Dissociative Seizures Unknown status NCT00688727 Not Applicable
5 Evaluation of a Telephone Follow-up Procedure on the Quality of Life in Psychogenic Non-epileptic Seizures Unknown status NCT02311829 Not Applicable
6 Tonicity Monitor For Epilepsy and Hypertonic Disorders Unknown status NCT02110589 Not Applicable
7 Comparing Different Treatments in Reducing Dissociative Seizure Occurrence Completed NCT02325544 Not Applicable
8 Motivational Interviewing to Enhance Adherence of Patients With Psychogenic Non-epileptic Seizures Completed NCT02598076 Not Applicable
9 Stress and Seizures - Can a Brief Self-help Book Help? Completed NCT02465047 Not Applicable
10 Project UPLIFT for Psychogenic Non-Epileptic Seizures Recruiting NCT03329703 Not Applicable
11 Emotional Lived in Patients Suffering From Psychogenic Nonepileptic Seizures : Study by Functional Magnetic Resonance Imaging Recruiting NCT02976545 Not Applicable
12 Treatment Outcomes of CBT for PNES Recruiting NCT02801136 Not Applicable
13 Pilot Study of Cognitive Behavioral Therapy-Informed Physical Therapy Intervention in Functional Neurological Disorders Recruiting NCT03731078
14 Neuroimaging Biomarker for Seizures Recruiting NCT03441867 Not Applicable
15 Neuroimaging Biomarkers of Prognosis in Motor Functional Neurological Disorders Recruiting NCT03398070
16 Development of an Epileptic Seizure Detection Algorithm by Continuous Analysis of the Electrocardiogram Recruiting NCT03369522
17 Automated Identification of Psychogenic Nonepileptic Seizures Enrolling by invitation NCT03013348
18 Treating Non-epileptic Seizures Using Magnetic Brain Stimulation Enrolling by invitation NCT02796924 Not Applicable
19 Detecting PNES With Single-channel sEMG Enrolling by invitation NCT03313362 Not Applicable

Search NIH Clinical Center for Dissociative Seizures

Genetic Tests for Dissociative Seizures

Anatomical Context for Dissociative Seizures

MalaCards organs/tissues related to Dissociative Seizures:

42
Brain, Temporal Lobe, Heart, Testes, Eye

Publications for Dissociative Seizures

Articles related to Dissociative Seizures:

(show top 50) (show all 426)
# Title Authors Year
1
A Comparison Among the Prevalence of Alexithymia in Patients With Psychogenic Nonepileptic Seizures, Epilepsy, and the Healthy Population: A Systematic Review of the Literature. ( 30876655 )
2019
2
Explaining dissociative seizures: a neuropsychological perspective. ( 30755460 )
2019
3
Exploring psychiatrists' perspectives of working with patients with dissociative seizures in the UK healthcare system as part of the CODES trial: a qualitative study. ( 31072856 )
2019
4
Are psychogenic nonepileptic seizures risk factors for a worse outcome in patients with refractory mesial temporal epilepsy submitted to surgery? Results of a retrospective cohort study. ( 30780075 )
2019
5
Psychological trauma, somatization, dissociation, and psychiatric comorbidities in patients with psychogenic nonepileptic seizures compared with those in patients with intractable partial epilepsy. ( 30654229 )
2019
6
Self-reporting versus clinical scrutiny: the value of adding questionnaires to the routine evaluation of seizure disorders. An exploratory study on the differential diagnosis between epilepsy and psychogenic nonepileptic seizures. ( 30578096 )
2019
7
Novel features for capturing temporal variations of rhythmic limb movement to distinguish convulsive epileptic and psychogenic nonepileptic seizures. ( 30536390 )
2019
8
Parental consanguinity in patients with psychogenic nonepileptic seizures. ( 30959273 )
2019
9
Coping with stress: A pilot study of a self-help stress management intervention for patients with epileptic or psychogenic nonepileptic seizures. ( 30959274 )
2019
10
Long-term outcome in a sample of underprivileged patients with psychogenic nonepileptic seizures (PNES) living in Argentina. ( 30965202 )
2019
11
Randomized controlled trial of motivational interviewing for psychogenic nonepileptic seizures. ( 30980679 )
2019
12
Can short-term video-EEG substitute long-term video-EEG monitoring in psychogenic nonepileptic seizures? A prospective observational study. ( 30981120 )
2019
13
Sexual abuse and psychogenic nonepileptic seizures. ( 30982134 )
2019
14
Auras in psychogenic nonepileptic seizures. ( 31103792 )
2019
15
Preictal autonomic dynamics in psychogenic nonepileptic seizures. ( 30684800 )
2019
16
Dramatic presentations in psychogenic nonepileptic seizures. ( 30690408 )
2019
17
Pins and PNES: Systematic content analysis of Pinterest for information on psychogenic nonepileptic seizures (PNES). ( 30765306 )
2019
18
Quality of life and psychological dysfunction in traumatized and nontraumatized patients with psychogenic nonepileptic seizures (PNES). ( 30769279 )
2019
19
Natural history of patients with psychogenic nonepileptic seizures. ( 30772644 )
2019
20
Psychological long-term outcome in patients with psychogenic nonepileptic seizures. ( 30838655 )
2019
21
Potential use of leukocytosis and anion gap elevation in differentiating psychogenic nonepileptic seizures from epileptic seizures. ( 30868134 )
2019
22
Reliability of reported peri-ictal behavior to identify psychogenic nonepileptic seizures. ( 30884437 )
2019
23
Health-related quality of life in Veterans with epileptic and psychogenic nonepileptic seizures. ( 30893618 )
2019
24
Education in patients with psychogenic nonepileptic seizures. ( 30579135 )
2019
25
Psychogenic nonepileptic seizures, conversion, and somatic symptom disorders. ( 30610096 )
2019
26
Adherence with psychotherapy and treatment outcomes with psychogenic nonepileptic seizures. ( 30610097 )
2019
27
Gender differences in prevalence of psychiatric disorders, levels of alexithymia, and coping strategies in patients with refractory mesial temporal epilepsy and comorbid psychogenic nonepileptic seizures. ( 29574297 )
2018
28
Characteristics of Children Hospitalized for Psychogenic Nonepileptic Seizures Due to Conversion Disorder Versus Epilepsy. ( 29739840 )
2018
29
Autonomic and subjective responsivity to emotional images in people with dissociative seizures. ( 29285879 )
2018
30
Implicit attentional bias for facial emotion in dissociative seizures: Additional evidence. ( 29402630 )
2018
31
Research on dissociative seizures: A bibliometric analysis and visualization of the scientific landscape. ( 29705627 )
2018
32
A Case of Dissociative Seizures Presented like Myoclonic Epilepsy. ( 29736136 )
2018
33
Dual diagnosis of epilepsy and psychogenic nonepileptic seizures: Systematic review and meta-analysis of frequency, correlates, and outcomes. ( 30384103 )
2018
34
Experience of psychogenic nonepileptic seizures in the Canadian league against epilepsy: A survey describing current practices by neurologists and epileptologists. ( 30227342 )
2018
35
Differentiating epilepsy from psychogenic nonepileptic seizures using neuropsychological test data. ( 30172082 )
2018
36
Characteristics of patients with confirmed epilepsy and psychogenic nonepileptic seizures in Qatar. ( 29980425 )
2018
37
Neuropsychiatric features of the coexistence of epilepsy and psychogenic nonepileptic seizures. ( 29935759 )
2018
38
Psychogenic nonepileptic seizures in adults with epilepsy and intellectual disability: A neglected area. ( 29754013 )
2018
39
Effects of a psychotherapeutic group intervention in patients with refractory mesial temporal lobe epilepsy and comorbid psychogenic nonepileptic seizures: A nonrandomized controlled study. ( 29609146 )
2018
40
The frequency and management of seizures during psychological treatment among patients with psychogenic nonepileptic seizures and epilepsy. ( 29574898 )
2018
41
Temporally linked occurrences of epileptic and psychogenic nonepileptic seizures - Coincidental or pathogenically related? ( 30513453 )
2018
42
Psychogenic nonepileptic seizures in children and adolescents: An international cross-cultural study. ( 30517909 )
2018
43
Risk factors for the use of antiepileptic drugs in patients with psychogenic nonepileptic seizures. ( 30530132 )
2018
44
Medical health care utilization cost of patients presenting with psychogenic nonepileptic seizures. ( 30577087 )
2018
45
Psychogenic Nonepileptic Seizures (PNES) as a Network Disorder - Evidence From Neuroimaging of Functional (Psychogenic) Neurological Disorders. ( 30254510 )
2018
46
Global Warming for Psychogenic Nonepileptic Seizures? Report From ILAE Climate Survey. ( 30254516 )
2018
47
The application of artificial intelligence to understand the pathophysiological basis of psychogenic nonepileptic seizures. ( 30269939 )
2018
48
Provocative induction of psychogenic nonepileptic seizures: Noninferiority of an induction technique without versus with placebo. ( 30272374 )
2018
49
Narrative analysis of written accounts about living with epileptic or psychogenic nonepileptic seizures. ( 30286410 )
2018
50
Can home videos made on smartphones complement video-EEG in diagnosing psychogenic nonepileptic seizures? ( 30316048 )
2018

Variations for Dissociative Seizures

Expression for Dissociative Seizures

Search GEO for disease gene expression data for Dissociative Seizures.

Pathways for Dissociative Seizures

GO Terms for Dissociative Seizures

Sources for Dissociative Seizures

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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