MCID: DST001
MIFTS: 15

Distal Biliary Tract Carcinoma

Categories: Cancer diseases, Gastrointestinal diseases, Liver diseases

Aliases & Classifications for Distal Biliary Tract Carcinoma

MalaCards integrated aliases for Distal Biliary Tract Carcinoma:

Name: Distal Biliary Tract Carcinoma 12
Carcinoma of the Distal Biliary Tract 12
Distal Bile Duct Carcinoma 74

Classifications:



External Ids:

Disease Ontology 12 DOID:5923
NCIt 51 C7109
UMLS 74 C1333308

Summaries for Distal Biliary Tract Carcinoma

MalaCards based summary : Distal Biliary Tract Carcinoma, is also known as carcinoma of the distal biliary tract, and has symptoms including vomiting, abdominal pain and pruritus. Affiliated tissues include lymph node and liver.

Related Diseases for Distal Biliary Tract Carcinoma

Symptoms & Phenotypes for Distal Biliary Tract Carcinoma

UMLS symptoms related to Distal Biliary Tract Carcinoma:


vomiting, abdominal pain, pruritus, nausea, icterus, malaise

Drugs & Therapeutics for Distal Biliary Tract Carcinoma

Search Clinical Trials , NIH Clinical Center for Distal Biliary Tract Carcinoma

Genetic Tests for Distal Biliary Tract Carcinoma

Anatomical Context for Distal Biliary Tract Carcinoma

MalaCards organs/tissues related to Distal Biliary Tract Carcinoma:

42
Lymph Node, Liver

Publications for Distal Biliary Tract Carcinoma

Articles related to Distal Biliary Tract Carcinoma:

(show all 13)
# Title Authors Year
1
Validation of the Eighth American Joint Committee on Cancer Staging System for Distal Bile Duct Carcinoma. ( 29510611 )
2019
2
Survival outcome and prognostic factors after pancreatoduodenectomy for distal bile duct carcinoma: a retrospective multicenter study. ( 28612115 )
2017
3
Intra-pancreatic Distal Bile Duct Carcinoma is Morphologically, Genetically, and Clinically Distinct from Pancreatic Ductal Adenocarcinoma. ( 26956004 )
2016
4
When hepatic-side ductal margin is positive in N+ cases, additional resection of the bile duct is not necessary to render the negative hepatic-side ductal margin during surgery for extrahepatic distal bile duct carcinoma. ( 24657986 )
2014
5
The ratio between metastatic and examined lymph nodes is an independent prognostic factor for patients with resectable middle and distal bile duct carcinoma. ( 19596119 )
2010
6
Depth of tumor invasion better predicts prognosis than the current American Joint Committee on Cancer T classification for distal bile duct carcinoma. ( 19628081 )
2009
7
Distal bile duct carcinoma: prognostic factors after curative surgery. A series of 112 cases. ( 17176983 )
2007
8
p53 expression as a prognostic determinant in resected distal bile duct carcinoma. ( 10336811 )
1999
9
Genomic alterations in distal bile duct carcinoma by comparative genomic hybridization and karyotype analysis. ( 10502315 )
1999
10
DNA quantitation of distal bile duct carcinoma measured by image and flow cytometry. ( 10560507 )
1999
11
Diagnostic and prognostic value of incidence of K-ras codon 12 mutations in resected distal bile duct carcinoma. ( 9701213 )
1998
12
Prognostic value of cell proliferation (Ki-67 antigen) and nuclear DNA content in clinically resectable, distal bile duct carcinoma. ( 9869516 )
1998
13
Regression of a distal bile duct carcinoma after treatment with octreotide for 6 months. ( 9324171 )
1997

Variations for Distal Biliary Tract Carcinoma

Cosmic variations for Distal Biliary Tract Carcinoma:

9 (show top 50) (show all 1877)
# Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA GRCh38 Location Conf
1 COSM6974042 ZFHX3 biliary tract,bile duct,carcinoma,NS c.6964C>T p.R2322* 16:72795718-72795718 0
2 COSM6957143 ZFHX3 biliary tract,bile duct,carcinoma,NS c.3529+1G>A p.? 16:72829778-72829778 0
3 COSM6928728 YAP1 biliary tract,bile duct,carcinoma,NS c.434C>G p.T145S 11:102114256-102114256 0
4 COSM6986174 XPO1 biliary tract,bile duct,carcinoma,NS c.273G>T p.W91C 2:61522639-61522639 0
5 COSM6985358 XPO1 biliary tract,bile duct,carcinoma,NS c.338C>T p.T113M 2:61502274-61502274 0
6 COSM6975271 XPO1 biliary tract,bile duct,carcinoma,NS c.729G>T p.E243D 2:61498703-61498703 0
7 COSM968394 TSC2 biliary tract,bile duct,carcinoma,NS c.1819G>A p.A607T 16:2070558-2070558 0
8 COSM6939562 TSC2 biliary tract,bile duct,carcinoma,NS c.1783C>T p.Q595* 16:2070522-2070522 0
9 COSM6923580 TSC1 biliary tract,bile duct,carcinoma,NS c.2551C>T p.Q851* 9:132900789-132900789 0
10 COSM4172016 TSC1 biliary tract,bile duct,carcinoma,NS c.737+1G>A p.? 9:132921362-132921362 0
11 COSM308173 TRIM28 biliary tract,bile duct,carcinoma,NS c.1475G>T p.R492L 19:58549053-58549053 0
12 COSM44463 TP53 biliary tract,bile duct,carcinoma,NS c.848G>T p.R283L 17:7673772-7673772 0
13 COSM10660 TP53 biliary tract,bile duct,carcinoma,NS c.818G>A p.R273H 17:7673802-7673802 0
14 COSM44745 TP53 biliary tract,bile duct,carcinoma,NS c.410T>A p.L137Q 17:7675202-7675202 0
15 COSM10662 TP53 biliary tract,bile duct,carcinoma,NS c.743G>A p.R248Q 17:7674220-7674220 0
16 COSM10687 TP53 biliary tract,bile duct,carcinoma,NS c.527G>A p.C176Y 17:7675085-7675085 0
17 COSM10731 TP53 biliary tract,bile duct,carcinoma,NS c.707A>G p.Y236C 17:7674256-7674256 0
18 COSM11196 TP53 biliary tract,bile duct,carcinoma,NS c.734G>T p.G245V 17:7674229-7674229 0
19 COSM43778 TP53 biliary tract,bile duct,carcinoma,NS c.713G>T p.C238F 17:7674250-7674250 0
20 COSM44309 TP53 biliary tract,bile duct,carcinoma,NS c.440T>G p.V147G 17:7675172-7675172 0
21 COSM44426 TP53 biliary tract,bile duct,carcinoma,NS c.568C>G p.P190A 17:7674963-7674963 0
22 COSM11073 TP53 biliary tract,bile duct,carcinoma,NS c.1024C>T p.R342* 17:7670685-7670685 0
23 COSM10648 TP53 biliary tract,bile duct,carcinoma,NS c.524G>A p.R175H 17:7675088-7675088 0
24 COSM11516 TP53 biliary tract,bile duct,carcinoma,NS c.841G>T p.D281Y 17:7673779-7673779 0
25 COSM43751 TP53 biliary tract,bile duct,carcinoma,NS c.673-1G>A p.? 17:7674291-7674291 0
26 COSM44240 TP53 biliary tract,bile duct,carcinoma,NS c.514G>T p.V172F 17:7675098-7675098 0
27 COSM44918 TP53 biliary tract,bile duct,carcinoma,NS c.844C>A p.R282R 17:7673776-7673776 0
28 COSM10812 TP53 biliary tract,bile duct,carcinoma,NS c.722C>T p.S241F 17:7674241-7674241 0
29 COSM10935 TP53 biliary tract,bile duct,carcinoma,NS c.722C>A p.S241Y 17:7674241-7674241 0
30 COSM43635 TP53 biliary tract,bile duct,carcinoma,NS c.536A>T p.H179L 17:7675076-7675076 0
31 COSM44151 TP53 biliary tract,bile duct,carcinoma,NS c.535C>A p.H179N 17:7675077-7675077 0
32 COSM44192 TP53 biliary tract,bile duct,carcinoma,NS c.272G>A p.W91* 17:7676097-7676097 0
33 COSM43836 TP53 biliary tract,bile duct,carcinoma,NS c.475G>C p.A159P 17:7675137-7675137 0
34 COSM10742 TP53 biliary tract,bile duct,carcinoma,NS c.578A>G p.H193R 17:7674953-7674953 0
35 COSM10727 TP53 biliary tract,bile duct,carcinoma,NS c.438G>A p.W146* 17:7675174-7675174 0
36 COSM43779 TP53 biliary tract,bile duct,carcinoma,NS c.589G>A p.V197M 17:7674942-7674942 0
37 COSM44786 TP53 biliary tract,bile duct,carcinoma,NS c.694A>C p.I232L 17:7674269-7674269 0
38 COSM1522202 TP53 biliary tract,bile duct,carcinoma,NS c.1051A>T p.K351* 17:7670658-7670658 0
39 COSM44117 TP53 biliary tract,bile duct,carcinoma,NS c.775G>A p.D259N 17:7674188-7674188 0
40 COSM45679 TP53 biliary tract,bile duct,carcinoma,NS c.868C>T p.R290C 17:7673752-7673752 0
41 COSM10690 TP53 biliary tract,bile duct,carcinoma,NS c.473G>A p.R158H 17:7675139-7675139 0
42 COSM11090 TP53 biliary tract,bile duct,carcinoma,NS c.541C>T p.R181C 17:7675071-7675071 0
43 COSM6081949 TP53 biliary tract,bile duct,carcinoma,NS c.1060C>T p.Q354* 17:7670649-7670649 0
44 COSM6917440 TP53 biliary tract,bile duct,carcinoma,NS c.736A>C p.M246L 17:7674227-7674227 0
45 COSM10645 TP53 biliary tract,bile duct,carcinoma,NS c.527G>T p.C176F 17:7675085-7675085 0
46 COSM10656 TP53 biliary tract,bile duct,carcinoma,NS c.742C>T p.R248W 17:7674221-7674221 0
47 COSM10714 TP53 biliary tract,bile duct,carcinoma,NS c.473G>T p.R158L 17:7675139-7675139 0
48 COSM11071 TP53 biliary tract,bile duct,carcinoma,NS c.1009C>T p.R337C 17:7670700-7670700 0
49 COSM10749 TP53 biliary tract,bile duct,carcinoma,NS c.830G>T p.C277F 17:7673790-7673790 0
50 COSM10768 TP53 biliary tract,bile duct,carcinoma,NS c.535C>T p.H179Y 17:7675077-7675077 0

Expression for Distal Biliary Tract Carcinoma

Search GEO for disease gene expression data for Distal Biliary Tract Carcinoma.

Pathways for Distal Biliary Tract Carcinoma

GO Terms for Distal Biliary Tract Carcinoma

Sources for Distal Biliary Tract Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
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41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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