MCID: DVR006
MIFTS: 31

Diversion Colitis

Categories: Gastrointestinal diseases

Aliases & Classifications for Diversion Colitis

MalaCards integrated aliases for Diversion Colitis:

Name: Diversion Colitis 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:0060187
ICD10 33 K52
ICD9CM 35 558 558.9

Summaries for Diversion Colitis

Disease Ontology : 12 A colitis caused_by diversion of the fecal stream due to complication of ileostomy or colostomy.

MalaCards based summary : Diversion Colitis is related to colitis and inflammatory bowel disease. An important gene associated with Diversion Colitis is MUC2 (Mucin 2, Oligomeric Mucus/Gel-Forming), and among its related pathways/superpathways are Regulation of IFNA signaling and Folate Metabolism. Affiliated tissues include colon, and related phenotypes are cellular and immune system

Wikipedia : 76 Diversion colitis is an inflammation of the colon which can occur as a complication of ileostomy or... more...

Related Diseases for Diversion Colitis

Diseases related to Diversion Colitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 68)
# Related Disease Score Top Affiliating Genes
1 colitis 29.8 IL1B IL4 MUC2
2 inflammatory bowel disease 27.6 ICAM1 IL1B IL4 MUC2
3 microinvasive gastric cancer 10.4 CDH1 MUC2
4 signet ring cell adenocarcinoma 10.4 CDH1 MUC2
5 tubular adenocarcinoma 10.4 CDH1 MUC2
6 papillary adenocarcinoma 10.4 CDH1 MUC2
7 bile duct adenocarcinoma 10.4 CDH1 MUC2
8 epstein-barr virus-associated gastric carcinoma 10.4 CDH1 MUC2
9 gastrointestinal system benign neoplasm 10.4 CDH1 MUC2
10 intestinal benign neoplasm 10.4 CDH1 MUC2
11 gastric cancer, hereditary diffuse 10.3 CDH1 IL1B
12 amebiasis 10.3 ICAM1 MUC2
13 crohn's colitis 10.3 CDH1 IL1B
14 cholecystitis 10.3 CDH1 MUC2
15 actinic prurigo 10.2 ICAM1 IL1B
16 limbal stem cell deficiency 10.2 ICAM1 IL1B
17 colorectal adenocarcinoma 10.1 CDH1 MUC2
18 pulmonary edema 10.0 ICAM1 IL1B
19 lymphadenitis 10.0 ICAM1 IL1B
20 opisthorchiasis 10.0 IL1B IL4
21 cercarial dermatitis 10.0 IL1B IL4
22 primary amebic meningoencephalitis 9.9 IL1B IL4
23 eales disease 9.9 IL1B IL4
24 aphthous stomatitis 9.9 IL1B IL4
25 extrinsic cardiomyopathy 9.9 IL1B IL4
26 keratoconjunctivitis sicca 9.9 IL1B IL4
27 somatoform disorder 9.9 IL1B IL4
28 gastric adenocarcinoma 9.8 CDH1 IL1B MUC2
29 tonsillitis 9.8 IL1B IL4
30 aggressive periodontitis 9.8 IL1B IL4
31 neuritis 9.8 IL1B IL4
32 interstitial cystitis 9.8 CDH1 IL4
33 vernal keratoconjunctivitis 9.7 ICAM1 IL4
34 poliomyelitis 9.7 ICAM1 IL4
35 gingivitis 9.7 IL1B IL4
36 bardet-biedl syndrome 15 9.7 ICAM1 IL4
37 lichen disease 9.7 ICAM1 IL4
38 primary bacterial infectious disease 9.7 IL1B IL4
39 bronchial disease 9.7 IL1B IL4
40 allergic conjunctivitis 9.7 ICAM1 IL4
41 nasal cavity disease 9.7 ICAM1 IL4
42 nose disease 9.7 ICAM1 IL4
43 toxoplasmosis 9.6 IL1B IL4
44 conjunctivitis 9.6 ICAM1 IL4
45 parasitic protozoa infectious disease 9.6 ICAM1 IL4
46 keratoconjunctivitis 9.6 ICAM1 IL4
47 visceral myopathy 9.6
48 enterocolitis 9.6
49 microcolon 9.6
50 crohn's disease 9.6

Graphical network of the top 20 diseases related to Diversion Colitis:



Diseases related to Diversion Colitis

Symptoms & Phenotypes for Diversion Colitis

MGI Mouse Phenotypes related to Diversion Colitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.8 IL4 MUC2 SAMHD1 CDH1 EIF2AK3 ICAM1
2 immune system MP:0005387 9.7 IL4 MUC2 SAMHD1 CDH1 EIF2AK3 ICAM1
3 digestive/alimentary MP:0005381 9.65 IL4 MUC2 CDH1 EIF2AK3 ICAM1
4 mortality/aging MP:0010768 9.5 IL1B IL4 MUC2 SAMHD1 CDH1 EIF2AK3
5 neoplasm MP:0002006 8.92 IL1B MUC2 CDH1 ICAM1

Drugs & Therapeutics for Diversion Colitis

Search Clinical Trials , NIH Clinical Center for Diversion Colitis

Genetic Tests for Diversion Colitis

Anatomical Context for Diversion Colitis

MalaCards organs/tissues related to Diversion Colitis:

41
Colon

Publications for Diversion Colitis

Articles related to Diversion Colitis:

(show all 25)
# Title Authors Year
1
Diversion colitis and pouchitis: A mini-review. ( 29713128 )
2018
2
Deviation of the Fecal Stream in Colonic Bowel Segments Results in Increased Numbers of Isolated Lymphoid Follicles in the Submucosal Compartment in a Novel Murine Model of Diversion Colitis. ( 28884123 )
2017
3
EVALUATION OF ENEMAS CONTAINING SUCRALFATE IN TISSUE CONTENT OF MUC-2 PROTEIN IN EXPERIMENTAL MODEL OF DIVERSION COLITIS. ( 29257850 )
2017
4
Diversion colitis 25A years later: the phenomenon of the disease. ( 28357500 )
2017
5
Anti-inflammatory effects of enemas containing an oily extract of curcumin in an experimental model of diversion colitis. ( 27237942 )
2016
6
Efficacy of Combined Mesalazine Plus Corticosteroid Enemas for Diversion Colitis after Subtotal Colectomy for Ulcerative Colitis. ( 27403119 )
2016
7
Successful autologous fecal transplantation for chronic diversion colitis. ( 25300242 )
2014
8
Relationship between the severity of diversion colitis and the composition of colonic bacteria: a prospective study. ( 24672659 )
2014
9
Pathophysiology, clinical presentation and management of diversion colitis: A review of current literature. ( 25150021 )
2014
10
Ascidian (chordate-tunicate) and mammalian heparin enemas attenuate experimental diversion colitis. ( 24287143 )
2014
11
Evaluation of the application of enemas containing sucralfate in tissue content of neutral and acid mucins in experimental model of diversion colitis. ( 25252200 )
2014
12
Relationship between diversion colitis and quality of life in rectal cancer. ( 23382634 )
2013
13
Confocal laser endomicroscopy for the diagnosis of diversion colitis. ( 23012020 )
2012
14
Use of butyrate or glutamine in enema solution reduces inflammation and fibrosis in experimental diversion colitis. ( 22969190 )
2012
15
The importance of oxygen free radicals in the etiopathogenesis of diversion colitis in rats. ( 20877947 )
2010
16
Quantification by computerized morphometry of tissue levels of sulfomucins and sialomucins in diversion colitis in rats. ( 20498935 )
2010
17
Comparison of prophylactic and therapeutic use of short-chain fatty acid enemas in diversion colitis: a study in Wistar rats. ( 21340226 )
2010
18
An incidental enterocolic lymphocytic phlebitis pattern is seen commonly in the rectal stump of patients with diversion colitis superimposed on inflammatory bowel disease. ( 19147627 )
2009
19
Diversion colitis in a 19-year-old female with megacystis-microcolon-intestinal hypoperistalsis syndrome. ( 19582576 )
2009
20
How to treat diversion colitis?--Current state of medical knowledge, own research and experience. ( 19069697 )
2008
21
Antegrade irrigations of a surgically reconstructed Hartmann's pouch to treat intractable diversion colitis. ( 18344801 )
2008
22
Microcarcinoids associated with diversion colitis in a patient with Crohn's disease. ( 21172219 )
2008
23
Diversion colitis presenting with massive rectal distension and bilateral ureteric obstruction. ( 18443804 )
2008
24
Ischaemia: a pathogenetic clue in diversion colitis? ( 17824976 )
2007
25
Noninfectious colitides: collagenous colitis, lymphocytic colitis, diversion colitis, and chemically induced colitis. ( 20011361 )
2007

Variations for Diversion Colitis

Expression for Diversion Colitis

Search GEO for disease gene expression data for Diversion Colitis.

Pathways for Diversion Colitis

GO Terms for Diversion Colitis

Biological processes related to Diversion Colitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.5 ICAM1 IL1B IL4
2 positive regulation of T cell proliferation GO:0042102 9.37 IL1B IL4
3 positive regulation of nitric oxide biosynthetic process GO:0045429 9.26 ICAM1 IL1B
4 cellular response to organic substance GO:0071310 9.16 ICAM1 IL1B
5 negative regulation of endothelial cell apoptotic process GO:2000352 8.96 ICAM1 IL4
6 positive regulation of vascular endothelial growth factor production GO:0010575 8.62 EIF2AK3 IL1B

Sources for Diversion Colitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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