MCID: DVR002
MIFTS: 46

Diverticulitis

Categories: Gastrointestinal diseases

Aliases & Classifications for Diverticulitis

MalaCards integrated aliases for Diverticulitis:

Name: Diverticulitis 12 73 54 44 15 17 70

Classifications:



External Ids:

Disease Ontology 12 DOID:7475
MeSH 44 D004238
NCIt 50 C26752
SNOMED-CT 67 155779000
UMLS 70 C0012813

Summaries for Diverticulitis

Disease Ontology : 12 An intestinal disease characterized by the formation and inflammation of diverticula within the bowel wall.

MalaCards based summary : Diverticulitis is related to diverticulitis of colon and appendicitis. An important gene associated with Diverticulitis is FAM155A (Family With Sequence Similarity 155 Member A), and among its related pathways/superpathways are Innate Immune System and Proteoglycans in cancer. The drugs Ertapenem and Guaifenesin have been mentioned in the context of this disorder. Affiliated tissues include colon, appendix and small intestine, and related phenotype is immune system.

Wikipedia : 73 Diverticulitis, specifically colonic diverticulitis, is a gastrointestinal disease characterized by... more...

Related Diseases for Diverticulitis

Diseases related to Diverticulitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 687)
# Related Disease Score Top Affiliating Genes
1 diverticulitis of colon 31.8 PHGR1 LAMB4 FAM155A CRP ARHGAP15
2 appendicitis 31.1 TNF S100A9 MMP9 IL6 CRP
3 ileus 31.0 TNF IL6 CRP
4 irritable bowel syndrome 30.6 TNF IL6 CRP
5 pyoderma gangrenosum 30.4 TNF MMP9 CCR6
6 ischemic colitis 30.4 MMP9 CRP CCR6
7 intestinal obstruction 30.4 TNF IL6 CRP ATP4A ATP12A
8 intussusception 30.3 IL6 FGF2 CRP
9 ulcerative colitis 30.3 TNFSF15 TNF IL6 CRP CCR6
10 vaginal discharge 30.3 TNF IL6 CRP
11 pouchitis 30.3 TNF S100A9
12 constipation 30.3 IL6 CRP ATP4A ATP12A
13 osteomyelitis 30.2 TNF IL6 CRP
14 crohn's disease 30.2 TNFSF15 TNF S100A9 IL6 CRP CCR6
15 pyoderma 30.2 TNF MMP9 CRP CCR6
16 ileitis 30.2 TNF IL6 CCR6
17 volvulus of midgut 30.2 CRP ATP4A ATP12A
18 anal fistula 30.2 TNF MMP9 CRP
19 pyelonephritis 30.1 TNF MMP9 IL6 CRP
20 paralytic ileus 30.1 CRP ATP4A ATP12A
21 pustulosis of palm and sole 30.1 TNF CRP CCR6
22 toxic shock syndrome 30.1 TNF IL6 CRP
23 peptic ulcer disease 30.1 TNF MUC5AC ATP4A ATP12A
24 actinomycosis 30.1 TNF IL6 CRP
25 acute cystitis 30.1 TNF IL6 CRP CCR6
26 endocarditis 30.0 TNF IL6 CRP
27 active peptic ulcer disease 30.0 CRP ATP4A ATP12A
28 sarcoidosis 1 30.0 TNF S100A9 CRP CCR6
29 salpingitis 30.0 TNF IL6 CRP
30 intestinal perforation 29.9 TNF IL6 CRP ATP4A ATP12A
31 pancreatitis 29.9 TNF SERPINA1 IL6 CRP
32 erythema nodosum 29.9 TNF IL6 CRP
33 peptic ulcer perforation 29.9 CRP ATP4A ATP12A
34 infective endocarditis 29.9 TNF IL6 CRP
35 gastroenteritis 29.9 TNF MMP9 IL6 CRP
36 clostridium difficile colitis 29.9 CRP CCR6 ATP4A ATP12A
37 inguinal hernia 29.9 MMP9 MMP13 IL6 CRP
38 vitiligo-associated multiple autoimmune disease susceptibility 1 29.9 TNF FGF2 CCR6
39 cellulitis 29.9 TNF IL6 CRP CCR6
40 panniculitis 29.8 TNF SERPINA1 CRP
41 pneumatosis cystoides intestinalis 29.8 ATP4A ATP12A
42 endometritis 29.8 TNF SDC1 IL6
43 bacterial meningitis 29.8 TNF MMP9 IL6 CRP
44 meningitis 29.8 TNF MMP9 IL6 CRP
45 proctitis 29.8 TNF FGF2 CRP CCR6
46 compartment syndrome 29.7 TNF IL6 CRP
47 pharyngitis 29.7 TNF IL6 CRP
48 pleural empyema 29.7 SDC1 IL6 CRP
49 mediastinitis 29.7 CRP ATP4A ATP12A
50 bronchiectasis 29.7 TNF SERPINA1 IL6 CRP

Graphical network of the top 20 diseases related to Diverticulitis:



Diseases related to Diverticulitis

Symptoms & Phenotypes for Diverticulitis

MGI Mouse Phenotypes related to Diverticulitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 immune system MP:0005387 9.4 ARHGAP15 ATP4A CCR6 CRP IL6 MMP9

Drugs & Therapeutics for Diverticulitis

Drugs for Diverticulitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 98)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ertapenem Approved, Investigational Phase 4 153832-46-3 150610
2
Guaifenesin Approved, Investigational, Vet_approved Phase 4 93-14-1 3516
3
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
4
Methadone Approved Phase 4 76-99-3 4095
5
Phenylpropanolamine Approved, Vet_approved, Withdrawn Phase 4 14838-15-4 26934
6
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
7
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
8
Orphenadrine Approved Phase 4 83-98-7 4601
9
Hydrocodone Approved, Illicit, Investigational Phase 4 125-29-1 5284569
10
Ketorolac Approved Phase 4 74103-06-3, 66635-83-4 3826
11
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
12
Hydromorphone Approved, Illicit Phase 4 466-99-9 5284570
13
Ciprofloxacin Approved, Investigational Phase 4 85721-33-1 2764
14
Acetaminophen Approved Phase 4 103-90-2 1983
15
Bupivacaine Approved, Investigational Phase 4 2180-92-9, 38396-39-3 2474
16
Metronidazole Approved Phase 4 443-48-1 4173
17
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
18
Ibuprofen Approved Phase 4 15687-27-1 3672
19
Ceftriaxone Approved Phase 4 73384-59-5 5479530 5361919
20
Tigecycline Approved Phase 4 220620-09-7 5282044
21
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
22
Racepinephrine Approved Phase 4 329-65-7 838
23 Acetaminophen, hydrocodone drug combination Phase 4
24 Respiratory System Agents Phase 4
25 Psychotropic Drugs Phase 4
26 Excitatory Amino Acid Antagonists Phase 4
27 Cytochrome P-450 Enzyme Inhibitors Phase 4
28 Chlorpheniramine, phenylpropanolamine drug combination Phase 4
29 Parasympatholytics Phase 4
30 Muscarinic Antagonists Phase 4
31 Anesthetics, General Phase 4
32 Anticonvulsants Phase 4
33 Cholinergic Agents Phase 4
34 Anesthetics, Dissociative Phase 4
35 Anesthetics, Intravenous Phase 4
36 Antitussive Agents Phase 4
37 Ketorolac Tromethamine Phase 4
38 Cholinergic Antagonists Phase 4
39 Anti-Anxiety Agents Phase 4
40 Antiparkinson Agents Phase 4
41 Amoxicillin-Potassium Clavulanate Combination Phase 4
42 Anti-Bacterial Agents Phase 4
43 Anti-Infective Agents Phase 4
44 Anesthetics Phase 4
45 Narcotics Phase 4
46 Analgesics Phase 4
47 Cyclooxygenase Inhibitors Phase 4
48 Anesthetics, Local Phase 4
49 Antipyretics Phase 4
50 Clavulanic Acids Phase 4

Interventional clinical trials:

(show top 50) (show all 119)
# Name Status NCT ID Phase Drugs
1 A Prospective, Multicenter, Open-Label, Randomized Clinical Study to Evaluate the Duration of Treatment With Ertapenem in Acute Attacks of Sigmoid Diverticulitis Unknown status NCT00097734 Phase 4 ertapenem
2 Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery as Part of an Enhanced Recovery After Surgery Protocol: A Randomized Prospective Single- Center Trial. Unknown status NCT02958566 Phase 4 Acetaminophen;Gabapentin;Orphenadrine;Lidocaine;Marcaine;Ketamine;Methadone;Tramadol;Ketorolac;Morphine Sulfate;Fentanyl;Dilaudid;Hydrocodone-Acetaminophen Tab 5-325 MG;Morphine Sulfate;Fentanyl;Dilaudid;HYDROCODONE/ACETAMINOPHEN 5 Mg-325 Mg ORAL TABLET
3 DIABOLO Trial: A Multicenter Randomized Clinical Trial Investigating the Cost-effectiveness of Treatment Strategies With or Without Antibiotics for Uncomplicated Acute Diverticulitis. Unknown status NCT01111253 Phase 4 Amoxicillin-clavulanate
4 Impact of Six Patient Information Leaflets (PIL) on Doctor Patient Communication and Adherence in Emergency Ward Completed NCT02246361 Phase 4
5 Laparoscopic Versus Open Sigmoid Colectomy for Diverticular Disease: A Prospective Randomized Single-Blind Trial Completed NCT00453830 Phase 4
6 Randomized Trial Comparing Two Treatment Strategies for Acute Diverticulitis. Hospitalization or Ambulatory Antibiotic Treatment Completed NCT01081054 Phase 4
7 Multicentre Controlled, Randomized Clinical Trial to Compare the Efficacy and Safety of Ambulatory Treatment of Mild Acute Diverticulitis Without Antibiotics With the Standard Treatment With Antibiotics Completed NCT02785549 Phase 4 Ibuprofen;Acetaminophen;Amoxicillin/clavulanic acid
8 Prospective Randomized Clinical Trial Assessing the Efficacy of a Short Course of Intravenous Amoxicillin Plus Clavulanic Acid Followed by Oral Antibiotic in Patients With Uncomplicated Acute Diverticulitis Completed NCT00917592 Phase 4 amoxicillin plus clavulanic acid;amoxicillin plus clavulanic acid
9 Compression Anastomosis: Initial Clinical Experience With the ColonRingTM Completed NCT01056913 Phase 4
10 A Multicenter, Open-Label, Randomized Comparative Study of Tigecycline vs Ceftriaxone Sodium Plus Metronidazole for the Treatment of Hospitalized Subjects With Complicated Intra-abdominal Infection Completed NCT00230971 Phase 4 tigecycline;ceftriaxone plus metronidazole
11 A Multicenter, Open-Label, Randomized Comparative Study of Tigecycline vs Ceftriaxone Sodium Plus Metronidazole for the Treatment of Hospitalized Subjects With Complicated Intra-abdominal Infection Completed NCT00195351 Phase 4 tigecycline;ceftriaxone sodium + metronidazole
12 The Effect of Exparel on Post Operative Pain and Narcotic Use After Colon Surgery Completed NCT02052557 Phase 4 Bupivacaine;Bupivacaine liposome suspension
13 Laparoscopic Peritoneal Lavage or Resection for Generalised Peritonitis for Perforated Diverticulitis: a Nationwide Multicenter Randomised Trial Unknown status NCT01317485 Phase 3
14 Phase 3 Study of Lactobacillus Reuterii in Patients With Symptomatic Non-complicated Diverticular Disease Unknown status NCT01168154 Phase 3
15 Hartmann vs Resection With Anastomosis and Diverting Stoma for Peritonitis Caused by Perforated Left-sided Colon Diverticulitis: a Multicenter Prospective Randomized Study. Completed NCT01239927 Phase 2, Phase 3
16 A Randomized Prospective Double Blind Assessment of Goal-Directed Intraoperative Fluid Management in Hand Assisted Laparoscopic Colectomy: Standard Care Versus Either Colloid and Crystalloid Completed NCT00467922 Phase 3 Hextend;Lactated Ringers
17 Assessment of the Probiotic Symprove as a Dietary Supplement in Patients With Symptomatic Diverticular Disease Completed NCT02115867 Phase 3
18 A Phase III, Randomised, Double-Blind, Dose-Response, Stratified, Placebo-Controlled Study Evaluating the Safety and Efficacy of SPD476 Versus Placebo Over 104 Weeks in the Prevention of Recurrence of Diverticulitis. Completed NCT00545740 Phase 3 SPD476 (1.2g);SPD476 (2.4 g);SPD476 (4.8 g);Placebo
19 A Phase III, Randomised, Double-Blind, Dose-Response, Stratified, Placebo-Controlled Study Evaluating the Safety and Efficacy of SPD476 Versus Placebo Over 104 Weeks in the Prevention of Recurrence of Diverticulitis. Completed NCT00545103 Phase 3 SPD476, MMX™ mesalazine, 1.2g extended release tablet;SPD476, MMX™ mesalazine, 1.2g extended release tablet;SPD476, MMX™ mesalazine, 1.2g extended release tablet;Placebo
20 Evaluation of Efficacy of Mesalamine in the Long-term Prevention of Diverticulitis Flares Completed NCT01120340 Phase 3 mesalamine
21 Hartmann's Versus Primary Anastomosis in Left-sided Colon Perforation - A Prospective Randomized Multicenter Trial Completed NCT01233713 Phase 2, Phase 3
22 Prospective Randomized Study Comparing the Results of Digital Rectal Examination in the Supine and Lateral Decubitus Completed NCT01727388 Phase 3
23 Rifaximin Delayed Release (400 mg Tablet) for the Prevention of Recurrent Acute Diverticulitis and Diverticular Complications. A Phase II, Multicenter, Double-blind, Placebo-controlled, Randomized Clinical Trial Active, not recruiting NCT03469050 Phase 2, Phase 3 Rifaximin delayed released 400mg Tablet
24 Double-blind, Dose-response, Randomised, Placebo-controlled, Parallel Group, Multi-centre Phase III Clinical Study on the Efficacy and Tolerability of Mesalazine Granules vs. Placebo for the Prevention of Recurrence of Diverticulitis Terminated NCT01038739 Phase 3 Mesalazine;Mesalazine;Placebo
25 Double-blind, Randomized, Placebo-controlled, Parallel Group, Multi-centre Phase III Clinical Study on the Efficacy and Tolerability of Mesalazine Granules vs. Placebo for the Prevention of Recurrence of Diverticulitis Terminated NCT00695643 Phase 3 Mesalazine;Placebo
26 A Randomized, Double-blind, Placebo-controlled Study to Assess the Safety and Efficacy of a 12 Week Treatment of Acute Diverticulitis With Asacol® 2.4 g/Day (400 mg Mesalamine Tablet), Followed by a 9 Month Treatment-free Observation Period Completed NCT00554099 Phase 2 Mesalamine;Probiotic;Placebo;Antibiotic for Diverticulitis
27 A Randomised, Double-blind, Double-dummy, Multi-centre, Comparative Parallel-group Study to Evaluate the Efficacy of Oral Rifamycin SV-MMX® 400 mg b.i.d. vs. Rifamycin SV-MMX® 600 mg t.i.d. vs. Placebo in the Treatment of Acute Uncomplicated Diverticulitis Completed NCT01847664 Phase 2 Rifamycin SV-MMX® 400 mg b.i.d.;Rifamycin SV-MMX® 600 mg t.i.d.;Rifamycin SV-MMX® Placebo
28 End-to-End Compression Anastomosis for Left-sided Colectomy Endo-CAR Study Completed NCT00497263 Phase 2
29 Restoration of Bowel Function After Laparoscopic Colorectal Surgery: Effect of Intravenous Lidocaine Completed NCT01155440 Phase 2 Lidocaine
30 Spinal Analgesia for Colonic Resection Using an Enhanced Recovery After Surgery (ERAS) Program Completed NCT01477190 Phase 1, Phase 2 Spinal analgesia;Patient Control Analgesia (PCA) Morphine
31 A Randomized, Double-Blind, Placebo-Controlled Study Evaluating Asimadoline on the Duration of POI in Subjects Undergoing Laparoscopic/Hand-Assisted Lap Segmental Colonic Resection Secondary to Colon Cancer, Polypectomy or Diverticulitis Terminated NCT00443040 Phase 2 Asimadoline;Placebo
32 Open Label Clinical Study to Demonstrate the Utility of Intra-operative Perfusion Assessment Using NIR Fluorescence Angiography With the PINPOINT® Endoscopic Fluorescence Imaging System and to Assess the Impact of PINPOINT on the Surgical Decision Making Process and on Surgical Outcomes in Laparoscopic Left Anterior Resection Procedures Completed NCT01560377 Phase 1
33 Natural History of Sigmoid Diverticulitis: The Geneva Cohort Study Unknown status NCT01015378
34 Procalcitonin REveals Good Recovery After Acute Diverticulitis: the PREGRAD Study Unknown status NCT02817854
35 Predictive Value of C-Reactive Protein in Acute Diverticulitis Unknown status NCT01825967
36 Laparoscopic Lavage for Acute Non-Faeculant Diverticulitis Unknown status NCT01019239
37 Multicenter Randomized Study Comparing Morbidity and Quality of Life Associated in the Treatment by Surgical Resection and the Conservative Treatment, After Favorable Evolution of Purulent Peritonitis That Originates From Diverticulitis Treated by Mini-invasive Surgery. Unknown status NCT01837342
38 Prospective Randomized Clinical Trial for the Management of Uncomplicated Diverticulitis in Right Colon; Non-antibiotics Versus Antibiotics Unknown status NCT02314013 Cephalosporin + Metronidazole
39 The Role of Intestinal Microbiota Composition and Intestinal Permeability in the Development of (Complicated) Diverticular Disease. Unknown status NCT01493349
40 General Surgical Outcomes Quality Improvement Database (UH-SOCRATES) Unknown status NCT00622557
41 The Use of Fluorescent Imaging to Evaluate Bowel Anastomotic Perfusion Unknown status NCT01424293
42 Active Versus Non Active Drainage for the Treatment of Infected Intra-abdominal Collection: a Randomized Prospective Trial Unknown status NCT01513421
43 Diverticular Disease Register (REMAD) Unknown status NCT03325829
44 Feasibility, Safety and Outcome of Transrectal Hybrid-NOTES Anterior Resection Unknown status NCT01992406
45 Prospective Evaluation of Wound Management Using Vacuum Assisted Instillation Therapy in Emergent Contaminated Abdominal Surgeries Unknown status NCT02127164
46 Operative and Conservative Treatment in Right Colon Diverticulitis Patients Completed NCT04746326
47 Management of Patients With Uncomplicated Diverticulitis as Out-patient and Without Antibiotics Completed NCT01515150
48 Long-term Follow-up of Lung Transplant Recipients With Diverticulitis Completed NCT02132078
49 Scandinavian Diverticulitis Trial. Laparoscopic Lavage vs Primary Resection as Treatment for Perforated Diverticulitis. A Randomized Prospective Multicenter Trial Completed NCT01047462
50 Randomized Multicentric Controlled Clinical Trial of Parallel Groups to Evaluate the Non-therapeutic Inferiority of a Free Diet With a Progressive Diet, in the Treatment of Non-complicated Acute Diverticulitis Completed NCT03496090

Search NIH Clinical Center for Diverticulitis

Inferred drug relations via UMLS 70 / NDF-RT 51 :


Scopolamine
Scopolamine Hydrobromide

Cochrane evidence based reviews: diverticulitis

Genetic Tests for Diverticulitis

Anatomical Context for Diverticulitis

MalaCards organs/tissues related to Diverticulitis:

40
Colon, Appendix, Small Intestine, Kidney, Neutrophil, Liver, Thyroid

Publications for Diverticulitis

Articles related to Diverticulitis:

(show top 50) (show all 6707)
# Title Authors PMID Year
1
Increased distribution of collagen type III and reduced expression of matrix metalloproteinase 1 in patients with diverticular disease. 61 54
11686522 2001
2
[Sensitivity and specificity of alpha-1-antitrypsin and acid alpha-1-glycoprotein in colorectal carcinoma]. 61 54
1725848 1991
3
Acute appendiceal diverticulitis: a case report. 61
33717385 2021
4
Factors Associated With Decision Regret Among Patients With Diverticulitis in the Elective Setting. 61
33429225 2021
5
Enhanced Recovery Pathway Benefits Patients Undergoing Nonelective Colorectal Surgery. 61
32697898 2021
6
Laparoscopic resection and primary anastomosis for perforated diverticulitis: with or without loop ileostomy? 61
33486710 2021
7
Patients avoided important care during the early weeks of the coronavirus pandemic: diverticulitis patients were more likely to present with an abscess on CT. 61
32979139 2021
8
National Landscape of Unplanned 30-Day Readmission Rates for Acute Non-hemorrhagic Diverticulitis: Insight from National Readmission Database. 61
32358707 2021
9
Robotic elective colectomy for diverticular disease: short-term outcomes of 80 patients. 61
33185931 2021
10
Surgeons Underestimate the Importance of Surgical Topics for Non-Surgeons: Results of a National Survey. 61
32747321 2021
11
The Effect of Tocilizumab on Inflammatory Markers in Patients Hospitalized with Serious Infections. Case Series and Review of Literature. 61
33804790 2021
12
Bowel ultrasonography in acute abdomen: beyond acute appendicitis. 61
33551121 2021
13
Update on the management of sigmoid diverticulitis. 61
33727769 2021
14
Spontaneous colo-vesical and colo-cutaneous fistula complicating a sigmoid diverticulitis: A case report. 61
33592411 2021
15
The effect of national public health interventions for COVID-19 on emergency general surgery in Northland, New Zealand. 61
33475217 2021
16
Association of County-Level Social Vulnerability with Elective Versus Non-elective Colorectal Surgery. 61
32779084 2021
17
Late onset infectious complications and safety of tocilizumab in the management of COVID-19. 61
32790075 2021
18
Diagnostic performance of ultra-low dose versus standard dose CT for non-traumatic abdominal emergencies. 61
33714689 2021
19
The Impact of Obesity on Mortality and Clinical Outcomes in Patients with Acute Diverticulitis in the United States. 61
33548127 2021
20
Comparison of colonoscopy after colonic diverticulitis and positive fecal immunochemical tests for the detection of colorectal neoplasia. 61
33655030 2021
21
Risankizumab for treating chronic plaque psoriasis complicated by recurrent diverticulitis: A case report. 61
33410210 2021
22
Post-colonoscopy diverticulitis: A systematic review. 61
33763188 2021
23
Jejunal diverticulitis as an unusual cause of pylephlebitis. 61
33744364 2021
24
Management of colonic diverticulitis. 61
33762260 2021
25
Pancreatic pseudocyst extending into psoas muscle mimicking acute complicated diverticulitis: A case report. 61
33609941 2021
26
Acute Diverticulitis in Young Patients: A Review of the Changing Epidemiology and Etiology. 61
33786702 2021
27
Intra-abdominal Desmoid-Type Fibromatosis Mimicking Diverticulitis With Abscess: A Case Report. 61
33622914 2021
28
Conservative treatment of uncomplicated right-sided diverticulitis: a systematic review and meta-analysis. 61
33765173 2021
29
Sigmoid diverticulitis leading to Fournier's gangrene. 61
32687238 2021
30
Ultrasound can differentiate complicated and noncomplicated acute colonic diverticulitis: a prospective comparative study with computed tomography. 61
33765176 2021
31
Robotic sigmoidectomy for diverticulitis - Natural orifice extraction with stapleless hand-sewn intracorporeal anastomosis. 61
33709504 2021
32
Antibiotics Do Not Reduce Length of Hospital Stay for Uncomplicated Diverticulitis in a Pragmatic Double-Blind Randomized Trial. 61
32240832 2021
33
Failure of nonoperative management in patients with acute diverticulitis complicated by abscess: a systematic review. 61
33677750 2021
34
Damage control strategy in perforated diverticulitis with generalized peritonitis. 61
33726727 2021
35
Emergency laparoscopic Hartmann's procedure for Hinchey IV left colonic diverticulitis: A Video Vignette. 61
33655671 2021
36
Neutrophil-to-lymphocyte ratio as a predictor of complicated acute diverticulitis: A retrospective cohort study. 61
33643646 2021
37
Evidence-based treatment strategies for acute diverticulitis. 61
33156365 2021
38
Self-Expandable Metal Stents for Left Sided Colon Obstruction from Diverticulitis. A Single Center Retrospective Series. 61
33806811 2021
39
Delay to Intervention for Complicated Diverticulitis is Associated with Higher Inpatient Mortality. 61
33728590 2021
40
Bowel movements and risk of diverticulitis. 61
33716142 2021
41
History of Diverticulitis and Risk of Incident Cardiovascular Disease in Men: A Cohort Study. 61
33770332 2021
42
Surgical Management of Diverticulitis-Associated Clostridioides Difficile Infection. 61
33006061 2021
43
Diverticulitis. 61
33642945 2021
44
Prospectively Assigned AAST Grade versus Modified Hinchey Class and Acute Diverticulitis Outcomes. 61
33248670 2021
45
Evaluation and Medical Management of Uncomplicated Diverticulitis. 61
33642947 2021
46
Surgical Management of Recurrent Uncomplicated Diverticulitis. 61
33642948 2021
47
Laparoscopic Lavage in the Management of Hinchey III/IV Diverticulitis. 61
33642950 2021
48
Environmental and Dietary Risk Factors for Colonic Diverticulosis and Diverticulitis. 61
33723560 2021
49
Open vs Minimally Invasive Approach for Emergent Colectomy in Perforated Diverticulitis. 61
33555710 2021
50
Colonic diverticulitis in children: A retrospective study of sixteen patients. 61
33705582 2021

Variations for Diverticulitis

Expression for Diverticulitis

Search GEO for disease gene expression data for Diverticulitis.

Pathways for Diverticulitis

Pathways related to Diverticulitis according to GeneCards Suite gene sharing:

(show all 12)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.84 TNFSF15 TNFRSF18 TNF SERPINA1 S100A9 MUC5AC
2 12.07 TNF SDC1 MMP9 FGF2
3
Show member pathways
11.77 TNF S100A9 MUC5AC MMP9 MMP13 IL6
4 11.68 TNF MMP9 IL6 FGF2
5
Show member pathways
11.58 TNFSF15 TNFRSF18 TNF
6 11.47 MMP9 MMP13 FGF2
7
Show member pathways
11.41 TNF MMP9 IL6
8 11.28 TNF SDC1 IL6
9 11.28 TNFRSF18 TNF IL6 CCR6
10 11.23 TNF MMP9 IL6
11 10.82 TNF SERPINA1 MMP9 IL6 FGF2
12 10.71 TNF IL6 CRP

GO Terms for Diverticulitis

Cellular components related to Diverticulitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.77 TNFSF15 TNFRSF18 TNF SERPINA1 SDC1 S100A9
2 extracellular space GO:0005615 9.4 TNFSF15 TNF SERPINA1 S100A9 MUC5AC MMP9

Biological processes related to Diverticulitis according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.77 TNF SDC1 S100A9 IL6 CRP
2 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.65 TNFRSF18 TNF IL6
3 response to glucocorticoid GO:0051384 9.63 TNF SDC1 IL6
4 humoral immune response GO:0006959 9.58 TNF IL6 CCR6
5 cytokine-mediated signaling pathway GO:0019221 9.55 TNF SDC1 MMP9 IL6 FGF2
6 positive regulation of vascular smooth muscle cell proliferation GO:1904707 9.5 TNF MMP9 FGF2
7 regulation of neuroinflammatory response GO:0150077 9.49 MMP9 IL6
8 vascular endothelial growth factor production GO:0010573 9.43 TNF IL6
9 acute-phase response GO:0006953 9.43 SERPINA1 IL6 CRP
10 extracellular matrix organization GO:0030198 9.35 TNF MMP9 MMP13 FGF2 COLQ
11 negative regulation of lipid storage GO:0010888 8.8 TNF IL6 CRP

Molecular functions related to Diverticulitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.56 TNFSF15 TNF IL6 FGF2
2 sodium:potassium-exchanging ATPase activity GO:0005391 9.16 ATP4A ATP12A
3 potassium-transporting ATPase activity GO:0008556 8.96 ATP4A ATP12A
4 potassium:proton exchanging ATPase activity GO:0008900 8.62 ATP4A ATP12A

Sources for Diverticulitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
Content
Loading form....