MCID: DVR002
MIFTS: 44

Diverticulitis

Categories: Gastrointestinal diseases

Aliases & Classifications for Diverticulitis

MalaCards integrated aliases for Diverticulitis:

Name: Diverticulitis 12 76 55 44 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:7475
MeSH 44 D004238
NCIt 50 C26752
UMLS 73 C0012813

Summaries for Diverticulitis

Disease Ontology : 12 An intestinal disease characterized by the formation and inflammation of diverticula within the bowel wall.

MalaCards based summary : Diverticulitis is related to diverticulitis of colon and appendicitis. An important gene associated with Diverticulitis is TNFSF15 (TNF Superfamily Member 15), and among its related pathways/superpathways are IL-17 Family Signaling Pathways and Proteoglycans in cancer. The drugs Ertapenem and Menthol have been mentioned in the context of this disorder. Affiliated tissues include colon, liver and heart, and related phenotype is skeleton.

Wikipedia : 76 Diverticulitis, specifically colonic diverticulitis, is a gastrointestinal disease characterized by... more...

Related Diseases for Diverticulitis

Diseases related to Diverticulitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 161)
# Related Disease Score Top Affiliating Genes
1 diverticulitis of colon 32.8 ACADS DCXR
2 appendicitis 30.7 CRP MMP9 TNF
3 crohn's disease 30.2 CRP TNF TNFSF15
4 cellulitis 30.2 CRP TNF
5 infective endocarditis 29.8 CRP TNF
6 xanthogranulomatous pyelonephritis 29.7 CRP PKDREJ
7 bacterial meningitis 29.7 CRP MMP9 TNF
8 meningitis 29.6 CRP MMP9 TNF
9 pulmonary disease, chronic obstructive 29.6 CRP MMP9 TNF
10 aortic aneurysm, familial abdominal, 1 29.2 CRP MMP13 MMP9
11 arthritis 29.1 MMP13 MMP9 TNF
12 meckel's diverticulitis 12.1
13 small intestine diverticulitis 12.0
14 peritonitis 11.3
15 colonic disease 10.9
16 laryngitis 10.7 FGF2 TNF
17 radiation proctitis 10.7 FGF2 TNF
18 autoimmune inner ear disease 10.7 MMP9 TNF
19 scleritis 10.7 MMP9 TNF
20 transverse myelitis 10.6 MMP9 TNF
21 tuberculous meningitis 10.6 MMP9 TNF
22 melancholia 10.6 CRP TNF
23 rosacea 10.6 MMP9 TNF
24 relapsing fever 10.6 CRP TNF
25 chronic ulcer of skin 10.6 CRP FGF2
26 central nervous system vasculitis 10.6 CRP TNF
27 cheilitis 10.6 MMP9 TNF
28 louse-borne relapsing fever 10.5 CRP TNF
29 decubitus ulcer 10.5 CRP FGF2
30 tuberculous peritonitis 10.5 CRP TNF
31 ischemic heart disease 10.5 CRP TNF
32 chronic meningitis 10.5 CRP MMP9
33 streptococcal meningitis 10.5 CRP TNF
34 scrub typhus 10.5 CRP TNF
35 systolic heart failure 10.5 CRP TNF
36 pleural disease 10.4 CRP TNF
37 metaphyseal anadysplasia 10.4 MMP13 MMP9
38 apnea, obstructive sleep 10.4 CRP TNF
39 adult-onset still's disease 10.4 CRP TNF
40 perinatal necrotizing enterocolitis 10.4 CRP TNF
41 localized scleroderma 10.4 MMP13 TNF
42 sorsby fundus dystrophy 10.4 MMP13 MMP9
43 bone fracture 10.3 CRP FGF2
44 palindromic rheumatism 10.3 CRP TNF
45 fibrosarcoma 10.3 FGF2 MMP9 TNF
46 intestinal disease 10.3 CRP TNF TNFSF15
47 pyelitis 10.3 CRP PKDREJ
48 proctitis 10.2 CRP FGF2 TNF
49 pulmonary fibrosis, idiopathic 10.2 FGF2 MMP9 TNF
50 hemorrhagic fever with renal syndrome 10.2 CRP TNF

Graphical network of the top 20 diseases related to Diverticulitis:



Diseases related to Diverticulitis

Symptoms & Phenotypes for Diverticulitis

MGI Mouse Phenotypes related to Diverticulitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 skeleton MP:0005390 9.1 FGF2 MMP13 MMP9 SHOX2 TNF TNFSF15

Drugs & Therapeutics for Diverticulitis

Drugs for Diverticulitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 120)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ertapenem Approved, Investigational Phase 4,Not Applicable 153832-46-3 150610
2
Menthol Approved Phase 4,Phase 1 2216-51-5 16666
3
Ciprofloxacin Approved, Investigational Phase 4 85721-33-1 2764
4
Metronidazole Approved Phase 4,Not Applicable,Early Phase 1 443-48-1 4173
5
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
6
Lidocaine Approved, Vet_approved Phase 4,Phase 2,Not Applicable 137-58-6 3676
7
Ceftriaxone Approved Phase 4 73384-59-5 5479530 5361919
8
Bupivacaine Approved, Investigational Phase 4,Phase 1,Phase 2,Not Applicable 2180-92-9, 38396-39-3 2474
9
Minocycline Approved, Investigational Phase 4 10118-90-8 5281021
10
Morphine Approved, Investigational Phase 4,Phase 1,Phase 2,Not Applicable 57-27-2 5288826
11
Tigecycline Approved Phase 4 220620-09-7 5282044
12
Acetaminophen Approved Phase 4,Not Applicable 103-90-2 1983
13
Ibuprofen Approved Phase 4,Not Applicable 15687-27-1 3672
14
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
15
Rifaximin Approved, Investigational Phase 4 80621-81-4 6436173
16
Racepinephrine Approved Phase 4 329-65-7 838
17
Ketorolac Approved Phase 4 74103-06-3, 66635-83-4 3826
18
Hydrocodone Approved, Illicit Phase 4 125-29-1 5284569
19
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
20
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
21
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
22
Methadone Approved Phase 4 76-99-3 4095
23
Oxycodone Approved, Illicit, Investigational Phase 4 76-42-6 5284603
24
Orphenadrine Approved Phase 4 83-98-7 4601
25
Hydromorphone Approved, Illicit Phase 4 466-99-9 5284570
26
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
27
Guaifenesin Approved, Investigational, Vet_approved Phase 4 93-14-1 3516
28 Clavulanic Acid Phase 4
29 Amoxicillin-Potassium Clavulanate Combination Phase 4
30 Anti-Bacterial Agents Phase 4,Phase 2,Not Applicable,Early Phase 1
31 Antibiotics, Antitubercular Phase 4,Phase 2,Not Applicable,Early Phase 1
32 Anti-Infective Agents Phase 4,Phase 2,Not Applicable,Early Phase 1
33 Antiparasitic Agents Phase 4,Not Applicable,Early Phase 1
34 Antiprotozoal Agents Phase 4,Not Applicable,Early Phase 1
35 Antitubercular Agents Phase 4,Phase 2,Not Applicable,Early Phase 1
36 beta-Lactamase Inhibitors Phase 4
37 Analgesics Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
38 Central Nervous System Depressants Phase 4,Phase 1,Phase 2,Not Applicable
39 Gastrointestinal Agents Phase 4
40 Narcotics Phase 4,Phase 1,Phase 2,Not Applicable
41 Sodium Channel Blockers Phase 4,Phase 2,Not Applicable
42 Cyclooxygenase Inhibitors Phase 4,Not Applicable
43 Analgesics, Non-Narcotic Phase 4,Phase 3,Phase 2,Not Applicable
44 Analgesics, Opioid Phase 4,Phase 1,Phase 2,Not Applicable
45 Anesthetics Phase 4,Phase 2,Not Applicable
46 Nucleic Acid Synthesis Inhibitors Phase 4
47 Anesthetics, Local Phase 4,Phase 2,Not Applicable
48 Diuretics, Potassium Sparing Phase 4,Phase 2,Not Applicable
49 Anti-Arrhythmia Agents Phase 4,Phase 2,Not Applicable
50 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable

Interventional clinical trials:

(show top 50) (show all 110)
# Name Status NCT ID Phase Drugs
1 Diverticulitis: Antibiotics or Close Observation? Unknown status NCT01111253 Phase 4 Amoxicillin-clavulanate
2 Study to Evaluate the Duration of Treatment With Ertapenem in Acute Attacks of Sigmoid Diverticulitis Unknown status NCT00097734 Phase 4 ertapenem
3 Preoperative Assessment of Colon Tumor Unknown status NCT00114829 Phase 4
4 Trial Assessing the Efficacy of a Short Course of Intravenous Antibiotic Followed by Oral Antibiotic in Uncomplicated Acute Diverticulitis Completed NCT00917592 Phase 4 amoxicillin plus clavulanic acid;amoxicillin plus clavulanic acid
5 Hospitalization or Ambulatory Treatment of Acute Diverticulitis Completed NCT01081054 Phase 4
6 Laparoscopic Versus Open Sigmoid Colectomy for Diverticular Disease Completed NCT00453830 Phase 4
7 The Effect of Exparel on Post Operative Pain and Narcotic Use After Colon Surgery Completed NCT02052557 Phase 4 Bupivacaine;Bupivacaine liposome suspension
8 Impact of Six Patient Information Leaflets (PIL) on Doctor Patient Communication Completed NCT02246361 Phase 4
9 Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infection Completed NCT00195351 Phase 4 tigecycline;ceftriaxone sodium + metronidazole
10 Immunohistology in USDD and Correlation Between Bacterial Flora and Phlogosis Completed NCT02068482 Phase 4 Rifaximin
11 Study of Tomography of Nephrolithiasis Evaluation Completed NCT01451931 Phase 4
12 NITI CAR27 (ColonRing) Compression Anastomosis in Colorectal Surgery Completed NCT01056913 Phase 4
13 Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infection (cIAI) Completed NCT00230971 Phase 4 tigecycline;ceftriaxone plus metronidazole
14 Randomized Clinical Trial to Compare the Treatment of Mild Acute Diverticulitis With or Without Antibiotics Recruiting NCT02785549 Phase 4 Ibuprofen;Acetaminophen;Amoxicillin/clavulanic acid
15 Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery Recruiting NCT02958566 Phase 4 Acetaminophen;Gabapentin;Orphenadrine;Lidocaine;Marcaine;Ketamine;Methadone;Tramadol;Ketorolac;Morphine Sulfate;Fentanyl;Dilaudid;Hydrocodone-Acetaminophen Tab 5-325 MG;Morphine Sulfate;Fentanyl;Dilaudid;HYDROCODONE/ACETAMINOPHEN 5 Mg-325 Mg ORAL TABLET
16 Laparoscopic Peritoneal Lavage or Resection for Generalised Peritonitis for Perforated Diverticulitis Unknown status NCT01317485 Phase 3
17 Role Of Lactobacillus Reuteri DSM 17938 In The Non-Complicated Diverticular Disease Unknown status NCT01168154 Phase 3
18 Prevention of Recurrence of Diverticulitis Completed NCT00545103 Phase 3 SPD476, MMX™ mesalazine, 1.2g extended release tablet;SPD476, MMX™ mesalazine, 1.2g extended release tablet;SPD476, MMX™ mesalazine, 1.2g extended release tablet;Placebo
19 Prevention of Recurrence of Diverticulitis Completed NCT00545740 Phase 3 SPD476 (1.2g);SPD476 (2.4 g);SPD476 (4.8 g);Placebo
20 Hartmann vs R/A in Peritonitis by Perforated Diverticulitis Completed NCT01239927 Phase 2, Phase 3
21 Evaluation of Efficacy of Mesalamine in the Long-term Prevention of Diverticulitis Flares Completed NCT01120340 Phase 3 mesalamine
22 Effect of a Probiotic on Diverticular Symptoms Completed NCT02115867 Phase 3
23 Hartmann's Versus Primary Anastomosis in Left-sided Colon Perforation Completed NCT01233713 Phase 2, Phase 3
24 Informativeness to Digital Rectal Examination Completed NCT01727388 Phase 3
25 An Assessment of Goal-Directed Intraoperative Fluid Management in Hand Assisted Laparoscopic Colectomy Completed NCT00467922 Phase 3 Hextend;Lactated Ringers
26 A Study Of Tocilizumab in Patients With Moderate to Severe Active Rheumatoid Arthritis Who Have an Inadequate Response to or Are Unable to Tolerate Biologic and Non-Biologic Disease-modifying Antirheumatic Drugs (DMARDs) Completed NCT00891020 Phase 3 tocilizumab [RoActemra/Actemra];tocilizumab [RoActemra/Actemra];Nonbiologic DMARDs of investigator's choice
27 Single Port Colic Laparoscopic Surgery Recruiting NCT01959087 Phase 3
28 Rifaximin Delayed Release for the Prevention of Recurrent Acute Diverticulitis and Diverticular Complications. Not yet recruiting NCT03469050 Phase 2, Phase 3 Rifaximin delayed released 400mg Tablet
29 Randomized Multicentric Trial to Evaluate a Free Diet With a Progressive Diet in the Treatnent of Acute Diverticulitis Not yet recruiting NCT03496090 Phase 3
30 Two Doses Mesalazine Granules Versus Placebo for the Prevention of Recurrence of Diverticulitis Terminated NCT01038739 Phase 3 Mesalazine;Mesalazine;Placebo
31 Mesalazine Granules vs. Placebo for the Prevention of Recurrence of Diverticulitis Terminated NCT00695643 Phase 3 Mesalazine;Placebo
32 Rifamycin SV-MMX® 400 mg b.i.d. vs. Rifamycin SV-MMX® 600 mg t.i.d. vs. Placebo in Acute Uncomplicated Diverticulitis Completed NCT01847664 Phase 2 Rifamycin SV-MMX® 400 mg b.i.d.;Rifamycin SV-MMX® 600 mg t.i.d.;Rifamycin SV-MMX® Placebo
33 Asacol Acute Diverticulitis(DIVA)Study Completed NCT00554099 Phase 2 Mesalamine;Probiotic;Placebo;Antibiotic for Diverticulitis
34 End-to-End Compression Anastomosis for Left-sided Colectomy Endo-CAR Study Completed NCT00497263 Phase 2
35 Spinal Analgesia for Colonic Resection Using an Enhanced Recovery After Surgery (ERAS) Program Completed NCT01477190 Phase 1, Phase 2 Spinal analgesia;Patient Control Analgesia (PCA) Morphine
36 Bowel Function After Laparoscopic Colon Surgery: Effect of IV Lidocaine Completed NCT01155440 Phase 2 Lidocaine
37 Use of Autologous, Adult Adipose-Derived Stem/Stromal Cells in Inflammatory Bowel Disease Recruiting NCT02952131 Phase 1, Phase 2
38 Asimadoline for the Treatment of Post-Operative Ileus Terminated NCT00443040 Phase 2 Asimadoline;Placebo
39 Perfusion Assessment in Laparoscopic Left Anterior Resection Completed NCT01560377 Phase 1
40 PCT REveals Good Recovery After Acute Diverticulitis: the PREGRAD Study Unknown status NCT02817854
41 Acute Diverticulitis and C-Reactive Protein as a Prognostic Marker Unknown status NCT01825967
42 Randomized Clinical Trial for the Uncomplicated Diverticulitis in Right Colon Unknown status NCT02314013 Not Applicable Cephalosporin + Metronidazole
43 The Gut Microbiome in Diverticulitis and Diverticulosis Unknown status NCT02221713
44 LapLAND Laparoscopic Lavage for Acute Non-Faeculant Diverticulitis Unknown status NCT01019239 Not Applicable
45 Multicenter Study Comparing Morbidity and Quality of Life Associated in the Treatment by Surgical Resection and the Conservative Treatment, After Favorable Evolution of Purulent Peritonitis That Originates From Diverticulitis Treated by Mini-invasive Surg Unknown status NCT01837342 Not Applicable
46 Natural History of Sigmoid Diverticulitis: The Geneva Cohort Study Unknown status NCT01015378
47 Pathophysiology of Diverticular Disease Unknown status NCT01493349
48 Fluorescent Evaluation of Colorectal Anastamoses Unknown status NCT01424293 Not Applicable
49 Vacuum Assisted Therapy in Emergent Contaminated Abdominal Surgeries Unknown status NCT02127164 Not Applicable
50 Feasibility, Safety and Outcome of Transrectal Hybrid-NOTES Anterior Resection Unknown status NCT01992406

Search NIH Clinical Center for Diverticulitis

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: diverticulitis

Genetic Tests for Diverticulitis

Anatomical Context for Diverticulitis

MalaCards organs/tissues related to Diverticulitis:

41
Colon, Liver, Heart, Lung, Testes, Bone, Kidney

Publications for Diverticulitis

Articles related to Diverticulitis:

(show top 50) (show all 764)
# Title Authors Year
1
Endoscopic transluminal water irrigation for duodenal diverticulitis. ( 29969797 )
2018
2
Antibiotics versus no antibiotics in the treatment of acute uncomplicated diverticulitis - a systematic review and meta-analysis. ( 29323778 )
2018
3
Meta-analysis of surgical strategies in perforated left colonic diverticulitis with generalized peritonitis. ( 29931505 )
2018
4
Severity of Diverticulitis Does Not Influence Abdominal Complaints during Long-Term Follow-Up. ( 29428950 )
2018
5
Successfully Conservative Management of Delayed Cervical Spondylodiscitis with Epidural Abscess Caused by Esophageal Diverticulitis: A Case Report and Review of Literature. ( 29883818 )
2018
6
Selective association of nonaspirin NSAIDs with risk of diverticulitis. ( 29411119 )
2018
7
Acute diverticulitis and surgical treatment. ( 29366311 )
2018
8
Predicting Future Elective Colon Resection for Diverticulitis Using Patterns of Health Care Utilization. ( 29881759 )
2018
9
Inflammation management in acute diverticulitis: current perspectives. ( 29881303 )
2018
10
Authors reply: Damage control surgery in patients with generalized peritonitis secondary to perforated diverticulitis-the risk of overtreatment. ( 29980887 )
2018
11
It's Actually a Little Complicated: Antibiotics for Uncomplicated Diverticulitis. ( 29925917 )
2018
12
Tumour Characteristics of Patients with Colorectal Cancer after Acute Uncomplicated Diverticulitis. ( 29945147 )
2018
13
Impact of CT imaging on predicting the surgical management of acute diverticulitis. ( 29854710 )
2018
14
Prolonged Recurrent Abdominal Pain is Associated With Ongoing Underlying Mucosal Inflammation in Patients who had an Episode of Acute Complicated Diverticulitis. ( 29356787 )
2018
15
Epiploic Appendagitis Mimicking Recurrent Diverticulitis. ( 29850359 )
2018
16
Acute Diverticulitis Management. ( 29413216 )
2018
17
Management of acute uncomplicated diverticulitis without antibiotics: a systematic review, meta-analysis, and meta-regression of predictors of treatment failure. ( 29980885 )
2018
18
Management of complicated diverticulitis of the colon. ( 29863123 )
2018
19
Evidence for Dietary Fibre Modification in the Recovery and Prevention of Reoccurrence of Acute, Uncomplicated Diverticulitis: A Systematic Literature Review. ( 29382074 )
2018
20
Pyomyositis in the setting of complicated diverticulitis: case report. ( 29317845 )
2018
21
Colonoscopy-induced acute diverticulitis: myth or reality? ( 29344786 )
2018
22
Damage control surgery in patients with generalized peritonitis secondary to perforated diverticulitis: the risk of overtreatment. ( 29948522 )
2018
23
Gangrenous giant Meckel's diverticulitis masquerading acute appendicitis: a surgical conundrum. ( 29695030 )
2018
24
Surgical outcomes for diverticulitis in young patients: results from the NSQIP database. ( 29872947 )
2018
25
Correction to: Prevalence of colorectal cancer in acute uncomplicated diverticulitis and the role of the interval colonoscopy. ( 29808306 )
2018
26
Prospective Creation and Validation of the PREVENTT (Prediction and Enaction of Prevention Treatments Trigger) Scale for Surgical Site Infections (SSIs) in Patients With Diverticulitis. ( 29916880 )
2018
27
Solitary Cecal Diverticulitis Mimicking Cecal Carcinoma. ( 29866226 )
2018
28
A Rare Case of Acute Right-Sided Colonic Diverticulitis Presenting as Pancreatitis. ( 29397242 )
2018
29
Risk of Recurrent Disease and Surgery Following an Admission for Acute Diverticulitis. ( 29420430 )
2018
30
Jejunal diverticulitis in a healthy 91-year-old man. ( 29848538 )
2018
31
Acute gastrointestinal bleeding from appendiceal diverticulitis diagnosed preoperatively by combined short-interval computed tomography and colonoscopy: AA case report. ( 29334144 )
2018
32
Routine lower gastrointestinal endoscopy for radiographically confirmed acute diverticulitis. In whom and when is it indicated? ( 29900742 )
2018
33
Acute Diverticulitis Outcomes in the Acute Care Surgery Model. ( 29307613 )
2018
34
Enterobius vermicularis infestation leading to Meckel's diverticulitis in an adolescent boy: An extremely rare presentation. ( 29403216 )
2018
35
Long-term quality of life after conservative treatment versus surgery for different stages of acute sigmoid diverticulitis. ( 29397430 )
2018
36
Identification of a rare LAMB4 variant associated with familial diverticulitis through exome sequencing. ( 28595269 )
2017
37
Risk factors for complicated diverticulitis: systematic review and meta-analysis. ( 28799055 )
2017
38
Multicentre, controlled, randomized clinical trial to compare the efficacy and safety of ambulatory treatment of mild acute diverticulitis without antibiotics with the standard treatment with antibiotics. ( 28808771 )
2017
39
Is the Failure of Laparoscopic Peritoneal Lavage Predictable in Hinchey III Diverticulitis Management? ( 28796735 )
2017
40
Laparoscopic peritoneal lavage for perforated sigmoid diverticulitis: an example of surgical research failure. ( 28067988 )
2017
41
Management of Acute Diverticulitis. ( 28719679 )
2017
42
Emergency Hartmann's Procedure and Its Reversal: A Totally Laparoscopic 2-Step Surgery for the Treatment of Hinchey III and IV Diverticulitis. ( 28748737 )
2017
43
Sigmoid resection for diverticulitis is more difficult than for malignancies. ( 28084549 )
2017
44
Conservative Treatment of Acute Colonic Diverticulitis. ( 28942590 )
2017
45
Perforated Meckel's Diverticulitis. ( 28744739 )
2017
46
Evidence for laparoscopic peritoneal lavage for purulent diverticulitis. ( 29863121 )
2017
47
Jejunal diverticulitis secondary to enterolith: a case report. ( 29266700 )
2017
48
[Diverticulitis : Domain of conservative or drug therapy?] ( 28608124 )
2017
49
Meat intake and risk of diverticulitis among men. ( 28069830 )
2017
50
Meckel's diverticulitis: a rare entity of Meckel's diverticulum. ( 28064243 )
2017

Variations for Diverticulitis

Expression for Diverticulitis

Search GEO for disease gene expression data for Diverticulitis.

Pathways for Diverticulitis

GO Terms for Diverticulitis

Cellular components related to Diverticulitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.1 CRP FGF2 MMP13 MMP9 TNF TNFSF15

Biological processes related to Diverticulitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular matrix organization GO:0030198 9.43 FGF2 MMP9 TNF
2 embryonic morphogenesis GO:0048598 9.16 FGF2 SHOX2
3 negative regulation of lipid storage GO:0010888 8.96 CRP TNF
4 positive regulation of vascular smooth muscle cell proliferation GO:1904707 8.8 FGF2 MMP9 TNF

Molecular functions related to Diverticulitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.13 FGF2 TNF TNFSF15
2 tumor necrosis factor receptor binding GO:0005164 8.62 TNF TNFSF15

Sources for Diverticulitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....