MCID: DVR002
MIFTS: 46

Diverticulitis

Categories: Gastrointestinal diseases

Aliases & Classifications for Diverticulitis

MalaCards integrated aliases for Diverticulitis:

Name: Diverticulitis 12 76 55 44 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:7475
MeSH 44 D004238
NCIt 50 C26752
SNOMED-CT 68 18126004
UMLS 73 C0012813

Summaries for Diverticulitis

Disease Ontology : 12 An intestinal disease characterized by the formation and inflammation of diverticula within the bowel wall.

MalaCards based summary : Diverticulitis is related to diverticulitis of colon and appendicitis. An important gene associated with Diverticulitis is TNFSF15 (TNF Superfamily Member 15), and among its related pathways/superpathways are Degradation of the extracellular matrix and IL-17 Family Signaling Pathways. The drugs Metronidazole and Ciprofloxacin have been mentioned in the context of this disorder. Affiliated tissues include colon, kidney and liver, and related phenotype is homeostasis/metabolism.

Wikipedia : 76 Diverticulitis, specifically colonic diverticulitis, is a gastrointestinal disease characterized by... more...

Related Diseases for Diverticulitis

Diseases related to Diverticulitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 171)
# Related Disease Score Top Affiliating Genes
1 diverticulitis of colon 33.3 ACADS DCXR
2 appendicitis 30.8 CRP MMP9 TNF
3 ulcerative colitis 30.1 CRP TNF TNFSF15
4 burns 29.9 CRP TNF
5 bacterial meningitis 29.7 CRP MMP9 TNF
6 meningitis 29.7 CRP MMP9 TNF
7 pulmonary disease, chronic obstructive 29.7 CRP MMP9 TNF
8 aortic aneurysm, familial abdominal, 1 29.5 CRP MMP13 MMP9
9 meckel's diverticulitis 12.3
10 small intestine diverticulitis 12.2
11 peritonitis 11.5
12 colonic disease 11.1
13 colorectal cancer 10.3
14 fasciitis 10.3
15 necrotizing fasciitis 10.3
16 laryngitis 10.2 FGF2 TNF
17 radiation proctitis 10.2 FGF2 TNF
18 autoimmune inner ear disease 10.2 MMP9 TNF
19 diffuse infiltrative lymphocytosis syndrome 10.2 SDC1 TNF
20 crohn's disease 10.2
21 scleritis 10.2 MMP9 TNF
22 drug reaction with eosinophilia and systemic symptoms 10.2 CRP TNF
23 colitis 10.2
24 salpingitis 10.2 CRP TNF
25 periodontosis 10.2 MMP9 TNF
26 melancholia 10.2 CRP TNF
27 relapsing fever 10.2 CRP TNF
28 decubitus ulcer 10.2 CRP FGF2
29 central nervous system vasculitis 10.2 CRP TNF
30 transverse myelitis 10.2 MMP9 TNF
31 louse-borne relapsing fever 10.2 CRP TNF
32 streptococcal meningitis 10.2 CRP TNF
33 tuberculous peritonitis 10.1 CRP TNF
34 chronic meningitis 10.1 CRP MMP9
35 ischemic heart disease 10.1 CRP TNF
36 tuberculous meningitis 10.1 MMP9 TNF
37 mycoplasma pneumoniae pneumonia 10.1 CRP TNF
38 hypersensitivity reaction type iii disease 10.1 CRP TNF
39 thrombosis 10.1
40 cheilitis 10.1 MMP9 TNF
41 fibrosarcoma 10.1 FGF2 MMP9 TNF
42 scrub typhus 10.1 CRP TNF
43 orbital cellulitis 10.1 CRP SDC1
44 metaphyseal anadysplasia 10.1 MMP13 MMP9
45 rosacea 10.1 MMP9 TNF
46 proctitis 10.1 CRP FGF2 TNF
47 thrombophlebitis 10.1
48 irritable bowel syndrome 10.1
49 acute orbital inflammation 10.1 CRP SDC1
50 intestinal disease 10.1 CRP SDC1 TNF

Graphical network of the top 20 diseases related to Diverticulitis:



Diseases related to Diverticulitis

Symptoms & Phenotypes for Diverticulitis

MGI Mouse Phenotypes related to Diverticulitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.28 ACADS CRP FGF2 MMP13 MMP9 SDC1

Drugs & Therapeutics for Diverticulitis

Drugs for Diverticulitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 128)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Metronidazole Approved Phase 4,Not Applicable,Early Phase 1 443-48-1 4173
2
Ciprofloxacin Approved, Investigational Phase 4,Not Applicable 85721-33-1 2764
3
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
4
Ertapenem Approved, Investigational Phase 4,Not Applicable 153832-46-3 150610
5
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
6
Bupivacaine Approved, Investigational Phase 4,Phase 1,Phase 2,Not Applicable 2180-92-9, 38396-39-3 2474
7
Racepinephrine Approved Phase 4 329-65-7 838
8
Minocycline Approved, Investigational Phase 4 10118-90-8 5281021
9
Tigecycline Approved Phase 4 220620-09-7 5282044
10
Ceftriaxone Approved Phase 4 73384-59-5 5479530 5361919
11
Rifaximin Approved, Investigational Phase 4,Phase 2,Phase 3 80621-81-4 6436173
12
Acetaminophen Approved Phase 4,Not Applicable 103-90-2 1983
13
Ibuprofen Approved Phase 4,Not Applicable 15687-27-1 3672
14
Morphine Approved, Investigational Phase 4,Phase 1,Phase 2,Not Applicable 57-27-2 5288826
15
Lidocaine Approved, Vet_approved Phase 4,Phase 2,Not Applicable 137-58-6 3676
16
Guaifenesin Approved, Investigational, Vet_approved Phase 4 93-14-1 3516
17
Ketorolac Approved Phase 4 66635-83-4, 74103-06-3 3826
18
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
19
Oxycodone Approved, Illicit, Investigational Phase 4 76-42-6 5284603
20
Orphenadrine Approved Phase 4 83-98-7 4601
21
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
22
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
23
Hydromorphone Approved, Illicit Phase 4 466-99-9 5284570
24
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
25
Hydrocodone Approved, Illicit, Investigational Phase 4 125-29-1 5284569
26
Methadone Approved Phase 4 76-99-3 4095
27 Anti-Bacterial Agents Phase 4,Phase 2,Phase 3,Not Applicable,Early Phase 1
28 beta-Lactamase Inhibitors Phase 4
29 Antitubercular Agents Phase 4,Phase 2,Not Applicable,Early Phase 1
30 Anti-Infective Agents Phase 4,Phase 2,Phase 3,Not Applicable,Early Phase 1
31 Amoxicillin-Potassium Clavulanate Combination Phase 4
32 Clavulanic Acids Phase 4
33 Antibiotics, Antitubercular Phase 4,Phase 2,Not Applicable,Early Phase 1
34 Cola Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
35 Antiparasitic Agents Phase 4,Not Applicable,Early Phase 1
36 Antiprotozoal Agents Phase 4,Not Applicable,Early Phase 1
37 Narcotics Phase 4,Phase 1,Phase 2,Not Applicable
38 Central Nervous System Depressants Phase 4,Phase 1,Phase 2,Not Applicable
39 Analgesics Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
40 Epinephryl borate Phase 4
41 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
42 Anesthetics, Local Phase 4,Phase 2,Not Applicable
43 Anesthetics Phase 4,Phase 2,Not Applicable
44 Nucleic Acid Synthesis Inhibitors Phase 4,Phase 2,Phase 3
45 Gastrointestinal Agents Phase 4,Phase 2,Phase 3
46 Cyclooxygenase Inhibitors Phase 4,Not Applicable
47 Analgesics, Non-Narcotic Phase 4,Phase 3,Phase 2,Not Applicable
48 Anti-Inflammatory Agents, Non-Steroidal Phase 4,Phase 3,Phase 2,Not Applicable
49 Antirheumatic Agents Phase 4,Phase 3,Phase 2,Not Applicable
50 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Not Applicable

Interventional clinical trials:

(show top 50) (show all 115)
# Name Status NCT ID Phase Drugs
1 Diverticulitis: Antibiotics or Close Observation? Unknown status NCT01111253 Phase 4 Amoxicillin-clavulanate
2 Study to Evaluate the Duration of Treatment With Ertapenem in Acute Attacks of Sigmoid Diverticulitis Unknown status NCT00097734 Phase 4 ertapenem
3 Preoperative Assessment of Colon Tumor Unknown status NCT00114829 Phase 4
4 Trial Assessing the Efficacy of a Short Course of Intravenous Antibiotic Followed by Oral Antibiotic in Uncomplicated Acute Diverticulitis Completed NCT00917592 Phase 4 amoxicillin plus clavulanic acid;amoxicillin plus clavulanic acid
5 Hospitalization or Ambulatory Treatment of Acute Diverticulitis Completed NCT01081054 Phase 4
6 Laparoscopic Versus Open Sigmoid Colectomy for Diverticular Disease Completed NCT00453830 Phase 4
7 The Effect of Exparel on Post Operative Pain and Narcotic Use After Colon Surgery Completed NCT02052557 Phase 4 Bupivacaine;Bupivacaine liposome suspension
8 Impact of Six Patient Information Leaflets (PIL) on Doctor Patient Communication Completed NCT02246361 Phase 4
9 Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infection Completed NCT00195351 Phase 4 tigecycline;ceftriaxone sodium + metronidazole
10 Immunohistology in USDD and Correlation Between Bacterial Flora and Phlogosis Completed NCT02068482 Phase 4 Rifaximin
11 Study of Tomography of Nephrolithiasis Evaluation Completed NCT01451931 Phase 4
12 NITI CAR27 (ColonRing) Compression Anastomosis in Colorectal Surgery Completed NCT01056913 Phase 4
13 Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infection (cIAI) Completed NCT00230971 Phase 4 tigecycline;ceftriaxone plus metronidazole
14 Randomized Clinical Trial to Compare the Treatment of Mild Acute Diverticulitis With or Without Antibiotics Recruiting NCT02785549 Phase 4 Ibuprofen;Acetaminophen;Amoxicillin/clavulanic acid
15 Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery Recruiting NCT02958566 Phase 4 Acetaminophen;Gabapentin;Orphenadrine;Lidocaine;Marcaine;Ketamine;Methadone;Tramadol;Ketorolac;Morphine Sulfate;Fentanyl;Dilaudid;Hydrocodone-Acetaminophen Tab 5-325 MG;Morphine Sulfate;Fentanyl;Dilaudid;HYDROCODONE/ACETAMINOPHEN 5 Mg-325 Mg ORAL TABLET
16 Laparoscopic Peritoneal Lavage or Resection for Generalised Peritonitis for Perforated Diverticulitis Unknown status NCT01317485 Phase 3
17 Role Of Lactobacillus Reuteri DSM 17938 In The Non-Complicated Diverticular Disease Unknown status NCT01168154 Phase 3
18 Single Port Colic Laparoscopic Surgery Unknown status NCT01959087 Phase 3
19 Prevention of Recurrence of Diverticulitis Completed NCT00545103 Phase 3 SPD476, MMX™ mesalazine, 1.2g extended release tablet;SPD476, MMX™ mesalazine, 1.2g extended release tablet;SPD476, MMX™ mesalazine, 1.2g extended release tablet;Placebo
20 Prevention of Recurrence of Diverticulitis Completed NCT00545740 Phase 3 SPD476 (1.2g);SPD476 (2.4 g);SPD476 (4.8 g);Placebo
21 Hartmann vs R/A in Peritonitis by Perforated Diverticulitis Completed NCT01239927 Phase 2, Phase 3
22 Evaluation of Efficacy of Mesalamine in the Long-term Prevention of Diverticulitis Flares Completed NCT01120340 Phase 3 mesalamine
23 Effect of a Probiotic on Diverticular Symptoms Completed NCT02115867 Phase 3
24 Hartmann's Versus Primary Anastomosis in Left-sided Colon Perforation Completed NCT01233713 Phase 2, Phase 3
25 Informativeness to Digital Rectal Examination Completed NCT01727388 Phase 3
26 An Assessment of Goal-Directed Intraoperative Fluid Management in Hand Assisted Laparoscopic Colectomy Completed NCT00467922 Phase 3 Hextend;Lactated Ringers
27 A Study Of Tocilizumab in Patients With Moderate to Severe Active Rheumatoid Arthritis Who Have an Inadequate Response to or Are Unable to Tolerate Biologic and Non-Biologic Disease-modifying Antirheumatic Drugs (DMARDs) Completed NCT00891020 Phase 3 tocilizumab [RoActemra/Actemra];tocilizumab [RoActemra/Actemra];Nonbiologic DMARDs of investigator's choice
28 Rifaximin Delayed Release for the Prevention of Recurrent Acute Diverticulitis and Diverticular Complications. Not yet recruiting NCT03469050 Phase 2, Phase 3 Rifaximin delayed released 400mg Tablet
29 Randomized Multicentric Trial to Evaluate a Free Diet With a Progressive Diet in the Treatnent of Acute Diverticulitis Not yet recruiting NCT03496090 Phase 3
30 Two Doses Mesalazine Granules Versus Placebo for the Prevention of Recurrence of Diverticulitis Terminated NCT01038739 Phase 3 Mesalazine;Mesalazine;Placebo
31 Mesalazine Granules vs. Placebo for the Prevention of Recurrence of Diverticulitis Terminated NCT00695643 Phase 3 Mesalazine;Placebo
32 Rifamycin SV-MMX® 400 mg b.i.d. vs. Rifamycin SV-MMX® 600 mg t.i.d. vs. Placebo in Acute Uncomplicated Diverticulitis Completed NCT01847664 Phase 2 Rifamycin SV-MMX® 400 mg b.i.d.;Rifamycin SV-MMX® 600 mg t.i.d.;Rifamycin SV-MMX® Placebo
33 Asacol Acute Diverticulitis(DIVA)Study Completed NCT00554099 Phase 2 Mesalamine;Probiotic;Placebo;Antibiotic for Diverticulitis
34 End-to-End Compression Anastomosis for Left-sided Colectomy Endo-CAR Study Completed NCT00497263 Phase 2
35 Spinal Analgesia for Colonic Resection Using an Enhanced Recovery After Surgery (ERAS) Program Completed NCT01477190 Phase 1, Phase 2 Spinal analgesia;Patient Control Analgesia (PCA) Morphine
36 Bowel Function After Laparoscopic Colon Surgery: Effect of IV Lidocaine Completed NCT01155440 Phase 2 Lidocaine
37 Use of Autologous, Adult Adipose-Derived Stem/Stromal Cells in Inflammatory Bowel Disease Recruiting NCT02952131 Phase 1, Phase 2
38 Efficacy and Safety of Polidocanol Foam 3% in the Treatment of II Degree Hemorrhoidal Disease Recruiting NCT03791775 Phase 2 Polidocanol foam (Atossisclerol® 3%)
39 Asimadoline for the Treatment of Post-Operative Ileus Terminated NCT00443040 Phase 2 Asimadoline;Placebo
40 Perfusion Assessment in Laparoscopic Left Anterior Resection Completed NCT01560377 Phase 1
41 PCT REveals Good Recovery After Acute Diverticulitis: the PREGRAD Study Unknown status NCT02817854
42 Acute Diverticulitis and C-Reactive Protein as a Prognostic Marker Unknown status NCT01825967
43 Randomized Clinical Trial for the Uncomplicated Diverticulitis in Right Colon Unknown status NCT02314013 Not Applicable Cephalosporin + Metronidazole
44 The Gut Microbiome in Diverticulitis and Diverticulosis Unknown status NCT02221713
45 LapLAND Laparoscopic Lavage for Acute Non-Faeculant Diverticulitis Unknown status NCT01019239 Not Applicable
46 Multicenter Study Comparing Morbidity and Quality of Life Associated in the Treatment by Surgical Resection and the Conservative Treatment, After Favorable Evolution of Purulent Peritonitis That Originates From Diverticulitis Treated by Mini-invasive Surgery Unknown status NCT01837342 Not Applicable
47 Natural History of Sigmoid Diverticulitis: The Geneva Cohort Study Unknown status NCT01015378
48 Pathophysiology of Diverticular Disease Unknown status NCT01493349
49 Fluorescent Evaluation of Colorectal Anastamoses Unknown status NCT01424293 Not Applicable
50 Vacuum Assisted Therapy in Emergent Contaminated Abdominal Surgeries Unknown status NCT02127164 Not Applicable

Search NIH Clinical Center for Diverticulitis

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: diverticulitis

Genetic Tests for Diverticulitis

Anatomical Context for Diverticulitis

MalaCards organs/tissues related to Diverticulitis:

41
Colon, Kidney, Liver, Lung, Heart, Small Intestine, Breast

Publications for Diverticulitis

Articles related to Diverticulitis:

(show top 50) (show all 1264)
# Title Authors Year
1
Short article: Outcome of medical and surgical management for perforated jejunal diverticulitis. ( 30211720 )
2019
2
Perforated cecal diverticulitis with CT diagnosis and medical management. ( 30305862 )
2019
3
Surgery After an Initial Episode of Uncomplicated Diverticulitis: Does Time to Resection Matter? ( 30527478 )
2019
4
Endoscopic transluminal water irrigation for duodenal diverticulitis. ( 29969797 )
2018
5
Antibiotics versus no antibiotics in the treatment of acute uncomplicated diverticulitis - a systematic review and meta-analysis. ( 29323778 )
2018
6
Meta-analysis of surgical strategies in perforated left colonic diverticulitis with generalized peritonitis. ( 29931505 )
2018
7
Severity of Diverticulitis Does Not Influence Abdominal Complaints during Long-Term Follow-Up. ( 29428950 )
2018
8
Successfully Conservative Management of Delayed Cervical Spondylodiscitis with Epidural Abscess Caused by Esophageal Diverticulitis: A Case Report and Review of Literature. ( 29883818 )
2018
9
Selective association of nonaspirin NSAIDs with risk of diverticulitis. ( 29411119 )
2018
10
Acute diverticulitis and surgical treatment. ( 29366311 )
2018
11
Predicting Future Elective Colon Resection for Diverticulitis Using Patterns of Health Care Utilization. ( 29881759 )
2018
12
Inflammation management in acute diverticulitis: current perspectives. ( 29881303 )
2018
13
Authors reply: Damage control surgery in patients with generalized peritonitis secondary to perforated diverticulitis-the risk of overtreatment. ( 29980887 )
2018
14
It's Actually a Little Complicated: Antibiotics for Uncomplicated Diverticulitis. ( 29925917 )
2018
15
Tumour Characteristics of Patients with Colorectal Cancer after Acute Uncomplicated Diverticulitis. ( 29945147 )
2018
16
Impact of CT imaging on predicting the surgical management of acute diverticulitis. ( 29854710 )
2018
17
Prolonged Recurrent Abdominal Pain is Associated With Ongoing Underlying Mucosal Inflammation in Patients who had an Episode of Acute Complicated Diverticulitis. ( 29356787 )
2018
18
Epiploic Appendagitis Mimicking Recurrent Diverticulitis. ( 29850359 )
2018
19
Acute Diverticulitis Management. ( 29413216 )
2018
20
Management of acute uncomplicated diverticulitis without antibiotics: a systematic review, meta-analysis, and meta-regression of predictors of treatment failure. ( 29980885 )
2018
21
Management of complicated diverticulitis of the colon. ( 29863123 )
2018
22
Evidence for Dietary Fibre Modification in the Recovery and Prevention of Reoccurrence of Acute, Uncomplicated Diverticulitis: A Systematic Literature Review. ( 29382074 )
2018
23
Pyomyositis in the setting of complicated diverticulitis: case report. ( 29317845 )
2018
24
Colonoscopy-induced acute diverticulitis: myth or reality? ( 29344786 )
2018
25
Damage control surgery in patients with generalized peritonitis secondary to perforated diverticulitis: the risk of overtreatment. ( 29948522 )
2018
26
Gangrenous giant Meckel's diverticulitis masquerading acute appendicitis: a surgical conundrum. ( 29695030 )
2018
27
Surgical outcomes for diverticulitis in young patients: results from the NSQIP database. ( 29872947 )
2018
28
Correction to: Prevalence of colorectal cancer in acute uncomplicated diverticulitis and the role of the interval colonoscopy. ( 29808306 )
2018
29
Prospective Creation and Validation of the PREVENTT (Prediction and Enaction of Prevention Treatments Trigger) Scale for Surgical Site Infections (SSIs) in Patients With Diverticulitis. ( 29916880 )
2018
30
Solitary Cecal Diverticulitis Mimicking Cecal Carcinoma. ( 29866226 )
2018
31
A Rare Case of Acute Right-Sided Colonic Diverticulitis Presenting as Pancreatitis. ( 29397242 )
2018
32
Risk of Recurrent Disease and Surgery Following an Admission for Acute Diverticulitis. ( 29420430 )
2018
33
Jejunal diverticulitis in a healthy 91-year-old man. ( 29848538 )
2018
34
Acute gastrointestinal bleeding from appendiceal diverticulitis diagnosed preoperatively by combined short-interval computed tomography and colonoscopy: AA case report. ( 29334144 )
2018
35
Routine lower gastrointestinal endoscopy for radiographically confirmed acute diverticulitis. In whom and when is it indicated? ( 29900742 )
2018
36
Acute Diverticulitis Outcomes in the Acute Care Surgery Model. ( 29307613 )
2018
37
Enterobius vermicularis infestation leading to Meckel's diverticulitis in an adolescent boy: An extremely rare presentation. ( 29403216 )
2018
38
Aging, Obesity, and the Incidence of Diverticulitis: A Population-Based Study. ( 30193674 )
2018
39
Appendiceal diverticulitis as a cause of acute appendicitis. ( 30031549 )
2018
40
Perforated diverticulitis in the setting of ulcerative colitis: An unusual case report. ( 30005364 )
2018
41
Management outcomes of diverticulitis and colitis in patients with active cancer. ( 29801733 )
2018
42
Meckel's Diverticulum in Crohn's Disease Revisited: A Case of Meckel's Diverticulitis in a Patient with Stricturing Crohn's Disease. ( 30148017 )
2018
43
Perforated Meckel's Diverticulitis Mimicking Penetrating Crohn's Disease. ( 30031176 )
2018
44
Conservative treatment of duodenal diverticulitis perforation: a case report and literature review. ( 30214324 )
2018
45
Reduction of the frequency of recurrent diverticulitis episodes under treatment with the integrative medicine therapies Carpellum Mali comp. and Kalium aceticum comp.-A case report. ( 30219450 )
2018
46
Distinct Clinical Factors in Hospitalized Patients with Diverticular Bleeding and Diverticulitis. ( 30219818 )
2018
47
Suprapubic single-port approach for complicated diverticulitis. ( 30219934 )
2018
48
Meckel's diverticulitis: a laparoscopic approach. ( 30238766 )
2018
49
A differential host response to viral infection defines a subset of earlier-onset diverticulitis patients. ( 30240468 )
2018
50
Mesalazine to treat symptomatic uncomplicated diverticular disease and to prevent acute diverticulitis occurrence. A systematic review with meta-analysis of randomized, placebo-controlled trials. ( 30240473 )
2018

Variations for Diverticulitis

Expression for Diverticulitis

Search GEO for disease gene expression data for Diverticulitis.

Pathways for Diverticulitis

Pathways related to Diverticulitis according to GeneCards Suite gene sharing:

(show all 16)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.47 FGF2 MMP13 MMP9 SDC1
2
Show member pathways
12.07 MMP13 MMP9 TNF
3
Show member pathways
11.95 LAMB4 MMP13 MMP9 SDC1
4 11.8 MMP9 SDC1 TNF
5
Show member pathways
11.71 MMP9 SDC1 TNF
6 11.67 MMP13 MMP9 SDC1
7 11.6 FGF2 MMP9 TNF
8
Show member pathways
11.49 MMP13 MMP9 TNF
9 11.38 FGF2 MMP13 MMP9
10 11.23 FGF2 MMP9 SDC1 TNF
11 11.14 FGF2 MMP13 MMP9
12 11.03 FGF2 MMP9
13 10.93 FGF2 MMP9 TNF
14 10.9 FGF2 MMP9
15 10.77 CRP TNF
16 10.69 MMP9 SDC1

GO Terms for Diverticulitis

Cellular components related to Diverticulitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.43 CRP FGF2 MMP13 MMP9 TNF TNFSF15
2 extracellular region GO:0005576 9.17 CRP FGF2 MMP13 MMP9 SDC1 TNF

Biological processes related to Diverticulitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular matrix organization GO:0030198 9.54 FGF2 MMP9 TNF
2 leukocyte migration GO:0050900 9.5 MMP9 SDC1 TNF
3 embryonic morphogenesis GO:0048598 9.26 FGF2 SHOX2
4 cytokine-mediated signaling pathway GO:0019221 9.26 FGF2 MMP9 SDC1 TNF
5 negative regulation of lipid storage GO:0010888 9.16 CRP TNF
6 positive regulation of vascular smooth muscle cell proliferation GO:1904707 8.8 FGF2 MMP9 TNF

Molecular functions related to Diverticulitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.33 FGF2 TNF TNFSF15
2 identical protein binding GO:0042802 9.02 CRP DCXR MMP9 SDC1 TNF
3 tumor necrosis factor receptor binding GO:0005164 8.96 TNF TNFSF15

Sources for Diverticulitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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