Categories: Gastrointestinal diseases

Aliases & Classifications for Diverticulitis

MalaCards integrated aliases for Diverticulitis:

Name: Diverticulitis 12 74 54 43 15 17 71


External Ids:

Disease Ontology 12 DOID:7475
MeSH 43 D004238
NCIt 49 C26752
SNOMED-CT 67 18126004 307496006
UMLS 71 C0012813

Summaries for Diverticulitis

Disease Ontology : 12 An intestinal disease characterized by the formation and inflammation of diverticula within the bowel wall.

MalaCards based summary : Diverticulitis is related to diverticulitis of colon and appendicitis. An important gene associated with Diverticulitis is FAM155A (Family With Sequence Similarity 155 Member A), and among its related pathways/superpathways are IL-17 Family Signaling Pathways and Proteoglycans in cancer. The drugs Fentanyl and Ketorolac have been mentioned in the context of this disorder. Affiliated tissues include colon, appendix and kidney.

Wikipedia : 74 Diverticulitis, specifically colonic diverticulitis, is a gastrointestinal disease characterized by... more...

Related Diseases for Diverticulitis

Diseases related to Diverticulitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 477)
# Related Disease Score Top Affiliating Genes
1 diverticulitis of colon 33.7 PHGR1 LAMB4 FAM155A CRP ACADS
2 appendicitis 31.8 TNF S100A9 MMP9 CRP
3 acute cystitis 31.0 TNF CRP CCR6
4 intestinal obstruction 31.0 TNF CRP ATP12A APOLD1
5 ulcerative colitis 30.9 TNFSF15 TNF CRP CCR6
6 crohn's disease 30.9 TNFSF15 TNF S100A9 CRP CCR6
7 intestinal perforation 30.8 TNF CRP ATP12A
8 intussusception 30.8 FGF2 CRP APOLD1
9 constipation 30.7 TNF CRP ATP12A APOLD1
10 pyoderma gangrenosum 30.7 TNF MMP9 CCR6
11 ischemic colitis 30.6 MMP9 CRP CCR6
12 peptic ulcer disease 30.5 TNF MUC5AC ATP12A
13 cellulitis 30.5 TNF CRP CCR6
14 anal fistula 30.4 TNF MMP9 APOLD1
15 pyoderma 30.4 TNF MMP9 CRP CCR6
16 bacterial meningitis 30.4 TNF MMP9 CRP
17 volvulus of midgut 30.4 CRP ATP12A APOLD1
18 peptic ulcer perforation 30.3 CRP ATP12A
19 gastroenteritis 30.3 TNF MMP9 CRP
20 intestinal disease 30.3 TNF SDC1 CRP CCR6
21 sarcoidosis 1 30.3 TNF S100A9 CRP CCR6
22 pustulosis of palm and sole 30.2 TNF CRP CCR6
23 leprosy 3 30.2 TNFSF15 TNF CCR6
24 pneumatosis cystoides intestinalis 30.2 CRP ATP12A
25 igg4-related disease 30.2 SDC1 CRP CCR6
26 urinary tract obstruction 30.1 TNF CRP CCR6
27 hyper ige syndrome 30.1 TNF MMP9 CCR6
28 vasculitis 30.0 TNF SERPINA1 S100A9 CRP
29 marginal zone b-cell lymphoma 30.0 SDC1 CCR6 ATP12A
30 colorectal adenoma 30.0 TNF MMP9 CRP
31 bronchiectasis 29.9 TNF SERPINA1 CRP
32 fibromyalgia 29.9 TNF SERPINA1 CRP
33 inflammatory bowel disease 29.8 TNFSF15 TNFRSF18 TNF S100A9 MUC5AC MMP9
34 toxic megacolon 29.8 TNF CRP CCR6 ATP12A
35 peripheral nervous system disease 29.8 TNF FGF2 CRP COLQ CCR6
36 granulomatosis with polyangiitis 29.7 TNF SERPINA1 CRP CCR6
37 autoimmune disease 29.7 TNFRSF18 TNF MMP9 CRP CCR6
38 proctitis 29.7 TNF FGF2 CRP CCR6 APOLD1
39 skin disease 29.7 TNF S100A9 FGF2 CRP CCR6
40 myeloma, multiple 29.6 TNF SDC1 MMP9 FGF2 CRP CCR6
41 respiratory failure 29.5 TNF SERPINA1 SDC1 MUC5AC CRP CCR6
42 pulmonary disease, chronic obstructive 29.4 TNF SERPINA1 MUC5AC MMP9 CRP CCR6
43 juvenile rheumatoid arthritis 29.3 TNF S100A9 CRP
44 meckel's diverticulitis 12.5
45 small intestine diverticulitis 12.4
46 peritonitis 11.8
47 colonic disease 11.6
48 autoimmune inner ear disease 10.6 TNF MMP9
49 ileus 10.6
50 drug reaction with eosinophilia and systemic symptoms 10.6 TNF CRP

Graphical network of the top 20 diseases related to Diverticulitis:

Diseases related to Diverticulitis

Symptoms & Phenotypes for Diverticulitis

Drugs & Therapeutics for Diverticulitis

Drugs for Diverticulitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 122)
# Name Status Phase Clinical Trials Cas Number PubChem Id
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
Ketorolac Approved Phase 4 66635-83-4, 74103-06-3 3826
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
Methadone Approved Phase 4 76-99-3 4095
Hydrocodone Approved, Illicit, Investigational Phase 4 125-29-1 5284569
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
Hydromorphone Approved, Illicit Phase 4 466-99-9 5284570
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
Orphenadrine Approved Phase 4 83-98-7 4601
Guaifenesin Approved, Investigational, Vet_approved Phase 4 93-14-1 3516
Acetaminophen Approved Phase 4 103-90-2 1983
Ibuprofen Approved Phase 4 15687-27-1 3672
Rifaximin Approved, Investigational Phase 4 80621-81-4 6436173 46783403
Clavulanate Approved, Vet_approved Phase 4 58001-44-8 5280980
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
Ceftriaxone Approved Phase 4 73384-59-5 5361919 5479530
Tigecycline Approved Phase 4 220620-09-7 5282044
Bupivacaine Approved, Investigational Phase 4 2180-92-9, 38396-39-3 2474
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
Racepinephrine Approved Phase 4 329-65-7 838
21 Analgesics, Non-Narcotic Phase 4
22 Antirheumatic Agents Phase 4
23 Anti-Inflammatory Agents Phase 4
24 Anti-Inflammatory Agents, Non-Steroidal Phase 4
25 Respiratory System Agents Phase 4
26 Ketorolac Tromethamine Phase 4
27 Acetaminophen, hydrocodone drug combination Phase 4
28 Excitatory Amino Acid Antagonists Phase 4
29 Antitussive Agents Phase 4
30 Cholinergic Agents Phase 4
31 Parasympatholytics Phase 4
32 Anesthetics, Dissociative Phase 4
33 Antiparkinson Agents Phase 4
34 Anti-Anxiety Agents Phase 4
35 Anesthetics, General Phase 4
36 Psychotropic Drugs Phase 4
37 Muscarinic Antagonists Phase 4
38 Anesthetics, Intravenous Phase 4
39 Cholinergic Antagonists Phase 4
40 Chlorpheniramine, phenylpropanolamine drug combination Phase 4
41 Anticonvulsants Phase 4
42 Analgesics Phase 4
43 Antipyretics Phase 4
44 Cyclooxygenase Inhibitors Phase 4
45 Cola Phase 4
46 Gastrointestinal Agents Phase 4
47 beta-Lactamase Inhibitors Phase 4
48 Anesthetics Phase 4
49 Anesthetics, Local Phase 4
50 Narcotics Phase 4

Interventional clinical trials:

(show top 50) (show all 151)
# Name Status NCT ID Phase Drugs
1 A Prospective, Multicenter, Open-Label, Randomized Clinical Study to Evaluate the Duration of Treatment With Ertapenem in Acute Attacks of Sigmoid Diverticulitis Unknown status NCT00097734 Phase 4 ertapenem
2 DIABOLO Trial: A Multicenter Randomized Clinical Trial Investigating the Cost-effectiveness of Treatment Strategies With or Without Antibiotics for Uncomplicated Acute Diverticulitis. Unknown status NCT01111253 Phase 4 Amoxicillin-clavulanate
3 Preoperative Assessment of Colon Tumor: A Prospective, Blinded Study. Unknown status NCT00114829 Phase 4
4 Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery as Part of an Enhanced Recovery After Surgery Protocol: A Randomized Prospective Single- Center Trial. Unknown status NCT02958566 Phase 4 Acetaminophen;Gabapentin;Orphenadrine;Lidocaine;Marcaine;Ketamine;Methadone;Tramadol;Ketorolac;Morphine Sulfate;Fentanyl;Dilaudid;Hydrocodone-Acetaminophen Tab 5-325 MG;Morphine Sulfate;Fentanyl;Dilaudid;HYDROCODONE/ACETAMINOPHEN 5 Mg-325 Mg ORAL TABLET
5 Randomized Trial Comparing Two Treatment Strategies for Acute Diverticulitis. Hospitalization or Ambulatory Antibiotic Treatment Completed NCT01081054 Phase 4
6 Prospective Randomized Clinical Trial Assessing the Efficacy of a Short Course of Intravenous Amoxicillin Plus Clavulanic Acid Followed by Oral Antibiotic in Patients With Uncomplicated Acute Diverticulitis Completed NCT00917592 Phase 4 amoxicillin plus clavulanic acid;amoxicillin plus clavulanic acid
7 Multicentre Controlled, Randomized Clinical Trial to Compare the Efficacy and Safety of Ambulatory Treatment of Mild Acute Diverticulitis Without Antibiotics With the Standard Treatment With Antibiotics Completed NCT02785549 Phase 4 Ibuprofen;Acetaminophen;Amoxicillin/clavulanic acid
8 Impact of Six Patient Information Leaflets (PIL) on Doctor Patient Communication and Adherence in Emergency Ward Completed NCT02246361 Phase 4
9 Laparoscopic Versus Open Sigmoid Colectomy for Diverticular Disease: A Prospective Randomized Single-Blind Trial Completed NCT00453830 Phase 4
10 A Multicenter, Open-Label, Randomized Comparative Study of Tigecycline vs Ceftriaxone Sodium Plus Metronidazole for the Treatment of Hospitalized Subjects With Complicated Intra-abdominal Infection Completed NCT00195351 Phase 4 tigecycline;ceftriaxone sodium + metronidazole
11 Evaluation of Immunohistological Pattern in Patients With Uncomplicated Symptomatic Diverticular Disease and Correlation Between Intraluminal Bacterial Flora and Phlogosis Completed NCT02068482 Phase 4 Rifaximin
12 Compression Anastomosis: Initial Clinical Experience With the ColonRingTM Completed NCT01056913 Phase 4
13 A Multicenter, Open-Label, Randomized Comparative Study of Tigecycline vs Ceftriaxone Sodium Plus Metronidazole for the Treatment of Hospitalized Subjects With Complicated Intra-abdominal Infection Completed NCT00230971 Phase 4 tigecycline;ceftriaxone plus metronidazole
14 The Effect of Exparel on Post Operative Pain and Narcotic Use After Colon Surgery Completed NCT02052557 Phase 4 Bupivacaine;Bupivacaine liposome suspension
15 Phase 4 Study of Primary Use of the Vacuum Assisted Laparostomy in Treatment of Severe Peritonitis Completed NCT01531543 Phase 4
16 Laparoscopic Peritoneal Lavage or Resection for Generalised Peritonitis for Perforated Diverticulitis: a Nationwide Multicenter Randomised Trial Unknown status NCT01317485 Phase 3
17 Phase 3 Study of Lactobacillus Reuterii in Patients With Symptomatic Non-complicated Diverticular Disease Unknown status NCT01168154 Phase 3
18 Hartmann vs Resection With Anastomosis and Diverting Stoma for Peritonitis Caused by Perforated Left-sided Colon Diverticulitis: a Multicenter Prospective Randomized Study. Completed NCT01239927 Phase 2, Phase 3
19 A Phase III, Randomised, Double-Blind, Dose-Response, Stratified, Placebo-Controlled Study Evaluating the Safety and Efficacy of SPD476 Versus Placebo Over 104 Weeks in the Prevention of Recurrence of Diverticulitis. Completed NCT00545740 Phase 3 SPD476 (1.2g);SPD476 (2.4 g);SPD476 (4.8 g);Placebo
20 A Phase III, Randomised, Double-Blind, Dose-Response, Stratified, Placebo-Controlled Study Evaluating the Safety and Efficacy of SPD476 Versus Placebo Over 104 Weeks in the Prevention of Recurrence of Diverticulitis. Completed NCT00545103 Phase 3 SPD476, MMX™ mesalazine, 1.2g extended release tablet;SPD476, MMX™ mesalazine, 1.2g extended release tablet;SPD476, MMX™ mesalazine, 1.2g extended release tablet;Placebo
21 Evaluation of Efficacy of Mesalamine in the Long-term Prevention of Diverticulitis Flares Completed NCT01120340 Phase 3 mesalamine
22 Assessment of the Probiotic Symprove as a Dietary Supplement in Patients With Symptomatic Diverticular Disease Completed NCT02115867 Phase 3
23 A Randomized Prospective Double Blind Assessment of Goal-Directed Intraoperative Fluid Management in Hand Assisted Laparoscopic Colectomy: Standard Care Versus Either Colloid and Crystalloid Completed NCT00467922 Phase 3 Hextend;Lactated Ringers
24 Prospective Randomized Study Comparing the Results of Digital Rectal Examination in the Supine and Lateral Decubitus Completed NCT01727388 Phase 3
25 Hartmann's Versus Primary Anastomosis in Left-sided Colon Perforation - A Prospective Randomized Multicenter Trial Completed NCT01233713 Phase 2, Phase 3
26 Rifaximin Delayed Release (400 mg Tablet) for the Prevention of Recurrent Acute Diverticulitis and Diverticular Complications. A Phase II, Multicenter, Double-blind, Placebo-controlled, Randomized Clinical Trial Active, not recruiting NCT03469050 Phase 2, Phase 3 Rifaximin delayed released 400mg Tablet
27 Double-blind, Randomized, Placebo-controlled, Parallel Group, Multi-centre Phase III Clinical Study on the Efficacy and Tolerability of Mesalazine Granules vs. Placebo for the Prevention of Recurrence of Diverticulitis Terminated NCT00695643 Phase 3 Mesalazine;Placebo
28 Double-blind, Dose-response, Randomised, Placebo-controlled, Parallel Group, Multi-centre Phase III Clinical Study on the Efficacy and Tolerability of Mesalazine Granules vs. Placebo for the Prevention of Recurrence of Diverticulitis Terminated NCT01038739 Phase 3 Mesalazine;Mesalazine;Placebo
29 The Analgesic Efficacy of Perioperative Δ9-THC (Namisol®) in Patients Undergoing Major Abdominal Surgery: A Randomized, Double Blinded, Placebo-controlled, Parallel Design Unknown status NCT01790555 Phase 2 Namisol;Diazepam/placebo
30 A Randomised, Double-blind, Double-dummy, Multi-centre, Comparative Parallel-group Study to Evaluate the Efficacy of Oral Rifamycin SV-MMX® 400 mg b.i.d. vs. Rifamycin SV-MMX® 600 mg t.i.d. vs. Placebo in the Treatment of Acute Uncomplicated Diverticulitis Completed NCT01847664 Phase 2 Rifamycin SV-MMX® 400 mg b.i.d.;Rifamycin SV-MMX® 600 mg t.i.d.;Rifamycin SV-MMX® Placebo
31 A Randomized, Double-blind, Placebo-controlled Study to Assess the Safety and Efficacy of a 12 Week Treatment of Acute Diverticulitis With Asacol® 2.4 g/Day (400 mg Mesalamine Tablet), Followed by a 9 Month Treatment-free Observation Period Completed NCT00554099 Phase 2 Mesalamine;Probiotic;Placebo;Antibiotic for Diverticulitis
32 End-to-End Compression Anastomosis for Left-sided Colectomy Endo-CAR Study Completed NCT00497263 Phase 2
33 Restoration of Bowel Function After Laparoscopic Colorectal Surgery: Effect of Intravenous Lidocaine Completed NCT01155440 Phase 2 Lidocaine
34 Spinal Analgesia for Colonic Resection Using an Enhanced Recovery After Surgery (ERAS) Program Completed NCT01477190 Phase 1, Phase 2 Spinal analgesia;Patient Control Analgesia (PCA) Morphine
35 Polyp Detection With The Peerscope System™: A Randomized Tandem Colonoscopy Study Completed NCT01549535 Phase 2
37 Effectiveness of Interleukin-6 Receptor Inhibitors in the Management of Patients With Severe SARS-CoV-2 Pneumonia: An Open-Label, Multicenter Sequential and Cluster Randomized Trial Recruiting NCT04322773 Phase 2 RoActemra iv;RoActemra sc;Kevzara sc
38 Use of Autologous Adult Adipose-Derived Stem/Stromal Cells in Inflammatory Bowel Disease Recruiting NCT02952131 Phase 1, Phase 2
39 Phase II Trial on the Efficacy and Safety of Sclerotherapy Using 3% Polidocanol Foam to Treat Second-degree Hemorrhoidal Disease Recruiting NCT03791775 Phase 2 Polidocanol foam (Atossisclerol® 3%)
40 A Pilot Study of Immune Checkpoint Inhibition (Durvalumab With or Without Tremelimumab) in Combination With Radiation Therapy in Patients With Unresectable Pancreatic Cancer Active, not recruiting NCT02311361 Phase 1, Phase 2
41 BARICIVID-19 STUDY: MultiCentre, Randomised, Phase IIa Clinical Trial Evaluating Efficacy and Tolerability of Baricitinib as add-on Treatment of In-patients With COVID-19 Compared to Standard Therapy Not yet recruiting NCT04393051 Phase 2 Baricitinib Oral Tablet
42 A Randomized, Double-Blind, Placebo-Controlled Study Evaluating Asimadoline on the Duration of POI in Subjects Undergoing Laparoscopic/Hand-Assisted Lap Segmental Colonic Resection Secondary to Colon Cancer, Polypectomy or Diverticulitis Terminated NCT00443040 Phase 2 Asimadoline;Placebo
43 A Phase II Study of Pevonedistat (MLN4924, TAK924) and Azacitidine as Maintenance Therapy After Allogeneic Stem Cell Transplantation for Non-Remission Acute Myelogenous Leukemia Terminated NCT03709576 Phase 2 Pevonedistat;Azacitidine
44 Open Label Clinical Study to Demonstrate the Utility of Intra-operative Perfusion Assessment Using NIR Fluorescence Angiography With the PINPOINT® Endoscopic Fluorescence Imaging System and to Assess the Impact of PINPOINT on the Surgical Decision Making Process and on Surgical Outcomes in Laparoscopic Left Anterior Resection Procedures Completed NCT01560377 Phase 1
45 Phase I Study of the Humanized Mik-Beta-1 Monoclonal Antibody Directed Toward IL-2/IL-15R Beta (CD122) That Blocks IL-15 Action In Patients With Refractory Celiac Disease Completed NCT01893775 Phase 1
46 An Open-Label Trial of Tocilizumab in Schizophrenia Completed NCT01696929 Phase 1 Tocilizumab
47 Predictive Value of C-Reactive Protein in Acute Diverticulitis Unknown status NCT01825967
48 Procalcitonin REveals Good Recovery After Acute Diverticulitis: the PREGRAD Study Unknown status NCT02817854
49 Natural History of Sigmoid Diverticulitis: The Geneva Cohort Study Unknown status NCT01015378
50 Multicenter Randomized Study Comparing Morbidity and Quality of Life Associated in the Treatment by Surgical Resection and the Conservative Treatment, After Favorable Evolution of Purulent Peritonitis That Originates From Diverticulitis Treated by Mini-invasive Surgery. Unknown status NCT01837342

Search NIH Clinical Center for Diverticulitis

Inferred drug relations via UMLS 71 / NDF-RT 50 :

Scopolamine Hydrobromide

Cochrane evidence based reviews: diverticulitis

Genetic Tests for Diverticulitis

Anatomical Context for Diverticulitis

MalaCards organs/tissues related to Diverticulitis:

Colon, Appendix, Kidney, Liver, Lung, Small Intestine, Heart

Publications for Diverticulitis

Articles related to Diverticulitis:

(show top 50) (show all 6408)
# Title Authors PMID Year
Increased distribution of collagen type III and reduced expression of matrix metalloproteinase 1 in patients with diverticular disease. 54 61
11686522 2001
[Sensitivity and specificity of alpha-1-antitrypsin and acid alpha-1-glycoprotein in colorectal carcinoma]. 61 54
1725848 1991
Incidence Trends, Comorbidities, and Outcomes of Pyogenic Liver Abscess Among Children: A Nationwide Population-based Analysis. 61
32142002 2020
MDCT in the Setting of Suspected Colonic Diverticulitis: Prevalence and Diagnostic Yield for Diverticulitis and Alternative Diagnoses. 61
32319796 2020
Laparoscopic Sigmoid Resection for Diverticulitis. 61
32496334 2020
Immune checkpoint inhibitors-induced acute diverticulitis. 61
32472816 2020
Family History Is Associated With Recurrent Diverticulitis After an Episode of Diverticulitis Managed Nonoperatively. 61
32217858 2020
Acute diverticulitis: Key features for guiding clinical management. 61
32422553 2020
Observational versus antibiotic treatment for uncomplicated diverticulitis: an individual-patient data meta-analysis. 61
32073652 2020
Utility of point-of-care ultrasound in patients with suspected diverticulitis in the emergency department. 61
32357249 2020
Can we better predict readmission for dehydration following creation of a diverting loop ileostomy: development and validation of a prediction model and web-based risk calculator. 61
31451920 2020
Initial clinical experience of single-incision robotic colorectal surgery with da Vinci SP platform. 61
32048755 2020
Emergency CT of abdominal complications of ingested fish bones: what not to miss. 61
32504281 2020
Study protocol for daiobotanpito combined with antibiotic therapy for treatment of acute diverticulitis: a study protocol for a randomized controlled trial. 61
32546262 2020
Systematic review and meta-analysis comparing primary resection and anastomosis versus Hartmann's procedure for the management of acute perforated diverticulitis with generalised peritonitis. 61
32124112 2020
Sigmoid resection with primary anastomosis versus the Hartmann's procedure for perforated diverticulitis with purulent or fecal peritonitis: a systematic review and meta-analysis. 61
32504331 2020
Comparison of American Association for the Surgery of Trauma grading scale with modified Hinchey classification in acute colonic diverticulitis: A pilot study. 61
32118825 2020
Cost-effectiveness of sigmoid resection with primary anastomosis or end colostomy for perforated diverticulitis: an analysis of the randomized Ladies trial. 61
32521053 2020
Opportunistic use of radiological measures of visceral adiposity for assessment of risk of colorectal adenoma. 61
32501646 2020
Segmental colectomy for ulcerative colitis: is there a place in selected patients without active colitis ? An international multicentric retrospective study in 72 patients. 61
32498084 2020
Distinguishing features between patients with acute diverticulitis and diverticular bleeding: Results from the REMAD registry. 61
32553704 2020
Computed tomography diagnosed first time diverticulitis and colorectal cancer. 61
32524190 2020
Human neutrophils activated by TLR8 agonists, with or without IFNγ, synthesize and release EBI3, but not IL-12, IL-27, IL-35, or IL-39. 61
32480433 2020
Comparison of clinical and pathological findings of patients undergoing elective colectomy for uncomplicated diverticulitis. 61
32483125 2020
Acute Colonic Diverticulitis and Cirrhosis: Outcomes of Laparoscopic Colectomy Compared with an Open Approach. 61
32229299 2020
Acute diverticulitis: old challenge, current trends, open questions. 61
32550727 2020
Acute Diverticulitis in Elderly Patients: Does Age Really Matter? 61
32485716 2020
Dietary Fiber and the Risk of Acute Diverticulitis. 61
31913190 2020
Diagnosis of appendiceal diverticulitis by multidetector computed tomography. 61
32172468 2020
Safety and efficacy of outpatient management for elderly patients with uncomplicated acute diverticulitis. 61
32199730 2020
Management of acute perforated diverticulitis with generalized peritonitis: is this the end of the Hartmann's era? 61
32277305 2020
Short- and Long-Term Outcomes of Right-Sided Diverticulitis: Over 15 Years of North American Experience. 61
32100064 2020
Disparities influencing rates of urgent/emergent surgery for diverticulitis in the state of Florida. 61
31526510 2020
Should diverticulitis be managed in primary care? An audit on the management of diverticulitis in primary care. 61
32554687 2020
Validation of the Adapted Clavien-Dindo in Trauma (ACDiT) Classifications in Medical and Surgical Management of Acute Diverticulitis. 61
32568744 2020
Surgical resection for diverticulitis using robotic natural orifice intracorporeal anastomosis and transrectal extraction approach: the NICE procedure. 61
31506878 2020
The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Treatment of Left-Sided Colonic Diverticulitis. 61
32384404 2020
Task-based characterization of a deep learning image reconstruction and comparison with filtered back-projection and a partial model-based iterative reconstruction in abdominal CT: A phantom study. 61
32574999 2020
No need to watch the clock: persistence during laparoscopic sigmoidectomy for diverticular disease. 61
32556770 2020
Pseudosarcomatous myofibroblastic proliferation of the appendix with an abdominal abscess due to diverticulum perforation: a case report. 61
32572649 2020
The retro-ileal pull-through technique for colorectal and coloanal anastomosis. 61
32506342 2020
A systematic review and meta-analysis of disease severity and risk of recurrence in young versus elderly patients with left-sided acute diverticulitis. 61
31972659 2020
Can American College of Surgeons NSQIP Data Tell Whether We are Using Hartmann's or Primary Anastomosis for Emergent Surgical Management of Acute Diverticulitis?: In Reply to Garfinkle and Boutros. 61
32334745 2020
Systematic Review and Meta-analysis on Colorectal Cancer Findings on Colonic Evaluation After CT-Confirmed Acute Diverticulitis. 61
32271220 2020
Swiss experience of atezolizumab for platinum-pretreated urinary tract carcinoma: the SAUL study in real-world practice. 61
32399958 2020
Expression of CA2 and CA9 carbonic anhydrases in ulcerative colitis and ulcerative colitis-associated colorectal cancer. 61
32410301 2020
Robotic Inguinal Hernia Repair. 61
32432334 2020
Imaging Findings of Acute Abdomen due to Complications of Meckel Diverticulum. 61
32063019 2020
The safety of baricitinib in patients with rheumatoid arthritis. 61
32174196 2020
Hot Pockets: The Adverse Admixture of Obesity and Diverticulitis. 61
32382900 2020

Variations for Diverticulitis

Expression for Diverticulitis

Search GEO for disease gene expression data for Diverticulitis.

Pathways for Diverticulitis

Pathways related to Diverticulitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
Show member pathways
11.79 TNF S100A9 MUC5AC MMP9
2 11.57 TNF SDC1 MMP9 FGF2
Show member pathways

GO Terms for Diverticulitis

Cellular components related to Diverticulitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.61 TNFSF15 TNF SERPINA1 S100A9 MUC5AC MMP9
2 extracellular region GO:0005576 9.4 TNFSF15 TNFRSF18 TNF SERPINA1 SDC1 S100A9

Biological processes related to Diverticulitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular matrix organization GO:0030198 9.56 TNF MMP9 FGF2 COLQ
2 activation of cysteine-type endopeptidase activity involved in apoptotic process GO:0006919 9.5 TNFSF15 TNF S100A9
3 leukocyte migration involved in inflammatory response GO:0002523 9.16 S100A9 CCR6
4 negative regulation of lipid storage GO:0010888 8.96 TNF CRP
5 positive regulation of vascular smooth muscle cell proliferation GO:1904707 8.8 TNF MMP9 FGF2

Sources for Diverticulitis

9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
31 HPO
32 ICD10
33 ICD10 via Orphanet
37 LifeMap
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
54 Novoseek
57 OMIM via Orphanet
61 PubMed
70 Tocris
72 UMLS via Orphanet
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