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MCID: DVR001
MIFTS: 25

Diverticulitis of Colon

Categories: Gastrointestinal diseases
Genes Tissues Related diseases Publications Drugs
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Aliases & Classifications for Diverticulitis of Colon

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MalaCards integrated aliases for Diverticulitis of Colon:

Name: Diverticulitis of Colon 12 15
Diverticular Disease of Colon 71
Colonic Diverticular Disease 12
Diverticulitis, Colonic 43

Classifications:

MalaCards categories:
Anatomical: Gastrointestinal diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:13254
MeSH 43 D004239
SNOMED-CT 67 111359004
UMLS 71 C0012814 C0012819
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Summaries for Diverticulitis of Colon

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Disease Ontology : 12 A colonic disease characterized by the formation and inflammation of diverticula within the colon wall.

MalaCards based summary : Diverticulitis of Colon, also known as diverticular disease of colon, is related to diverticulitis and irritable bowel syndrome. An important gene associated with Diverticulitis of Colon is VIT (Vitrin). The drugs Ertapenem and Clavulanate have been mentioned in the context of this disorder. Affiliated tissues include colon, liver and testes.

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Related Diseases for Diverticulitis of Colon

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Diseases related to Diverticulitis of Colon via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 34)
# Related Disease Score Top Affiliating Genes
1 diverticulitis 28.8 PHGR1 LAMB4 FAM155A CRP ACADS
2 irritable bowel syndrome 10.3
3 constipation 10.2
4 inflammatory bowel disease 10.1
5 colorectal adenoma 10.1
6 acute cystitis 10.1
7 adenoma 10.1
8 intestinal obstruction 10.1
9 ileus 10.1
10 ulcerative colitis 10.1
11 peritonitis 10.0
12 colorectal cancer 9.9
13 celiac disease 1 9.9
14 helicobacter pylori infection 9.9
15 cardiac conduction disease with or without dilated cardiomyopathy 9.9
16 polycystic kidney disease 9.9
17 diarrhea 9.9
18 toxic shock syndrome 9.9
19 basal cell carcinoma 9.9
20 lipomatosis 9.9
21 intestinal disease 9.9
22 kidney disease 9.9
23 end stage renal disease 9.9
24 appendicitis 9.9
25 paralytic ileus 9.9
26 actinomycosis 9.9
27 vasculitis 9.9
28 autosomal dominant polycystic kidney disease 9.9
29 enterovesical fistula 9.9
30 overgrowth syndrome 9.9
31 crohn's disease 9.9
32 urticaria 9.9
33 riboflavin deficiency 9.7 CRP ACADS
34 intracranial berry aneurysm 9.2 SLC25A16 CRP

Graphical network of the top 20 diseases related to Diverticulitis of Colon:



Diseases related to Diverticulitis of Colon
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Symptoms & Phenotypes for Diverticulitis of Colon

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Drugs & Therapeutics for Diverticulitis of Colon

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Drugs for Diverticulitis of Colon (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 61)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ertapenem Approved, Investigational Phase 4 153832-46-3 150610
2
Clavulanate Approved, Vet_approved Phase 4 58001-44-8 5280980
3
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
4
Ciprofloxacin Approved, Investigational Phase 4 85721-33-1 2764
5
Metronidazole Approved Phase 4 443-48-1 4173
6
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
7
Ketorolac Approved Phase 4 66635-83-4, 74103-06-3 3826
8
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
9
Methadone Approved Phase 4 76-99-3 4095
10
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
11
Hydrocodone Approved, Illicit, Investigational Phase 4 125-29-1 5284569
12
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
13
Hydromorphone Approved, Illicit Phase 4 466-99-9 5284570
14
Acetaminophen Approved Phase 4 103-90-2 1983
15
Morphine Approved, Investigational Phase 4 57-27-2 5288826
16
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
17
Orphenadrine Approved Phase 4 83-98-7 4601
18
Guaifenesin Approved, Investigational, Vet_approved Phase 4 93-14-1 3516
19
Bupivacaine Approved, Investigational Phase 4 2180-92-9, 38396-39-3 2474
20 Analgesics, Non-Narcotic Phase 4
21 Analgesics Phase 4
22 Antirheumatic Agents Phase 4
23 Anti-Inflammatory Agents Phase 4
24 Anti-Inflammatory Agents, Non-Steroidal Phase 4
25 Anti-Infective Agents Phase 4
26 Amoxicillin-Potassium Clavulanate Combination Phase 4
27 beta-Lactamase Inhibitors Phase 4
28 Respiratory System Agents Phase 4
29 Ketorolac Tromethamine Phase 4
30 Cytochrome P-450 Enzyme Inhibitors Phase 4
31 Sodium Channel Blockers Phase 4
32 Acetaminophen, hydrocodone drug combination Phase 4
33 Narcotics Phase 4
34 Excitatory Amino Acid Antagonists Phase 4
35 Antitussive Agents Phase 4
36 Cholinergic Agents Phase 4
37 Parasympatholytics Phase 4
38 Anesthetics, Dissociative Phase 4
39 Antiparkinson Agents Phase 4
40 Anti-Anxiety Agents Phase 4
41 Anti-Arrhythmia Agents Phase 4
42 Anesthetics, General Phase 4
43 Analgesics, Opioid Phase 4
44 Psychotropic Drugs Phase 4
45 Anesthetics Phase 4
46 Antipyretics Phase 4
47 Muscarinic Antagonists Phase 4
48 Cyclooxygenase Inhibitors Phase 4
49 Anesthetics, Intravenous Phase 4
50 Diuretics, Potassium Sparing Phase 4

Interventional clinical trials:

(show all 28)
# Name Status NCT ID Phase Drugs
1 A Prospective, Multicenter, Open-Label, Randomized Clinical Study to Evaluate the Duration of Treatment With Ertapenem in Acute Attacks of Sigmoid Diverticulitis Unknown status NCT00097734 Phase 4 ertapenem
2 DIABOLO Trial: A Multicenter Randomized Clinical Trial Investigating the Cost-effectiveness of Treatment Strategies With or Without Antibiotics for Uncomplicated Acute Diverticulitis. Unknown status NCT01111253 Phase 4 Amoxicillin-clavulanate
3 Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery as Part of an Enhanced Recovery After Surgery Protocol: A Randomized Prospective Single- Center Trial. Unknown status NCT02958566 Phase 4 Acetaminophen;Gabapentin;Orphenadrine;Lidocaine;Marcaine;Ketamine;Methadone;Tramadol;Ketorolac;Morphine Sulfate;Fentanyl;Dilaudid;Hydrocodone-Acetaminophen Tab 5-325 MG;Morphine Sulfate;Fentanyl;Dilaudid;HYDROCODONE/ACETAMINOPHEN 5 Mg-325 Mg ORAL TABLET
4 Laparoscopic Versus Open Sigmoid Colectomy for Diverticular Disease: A Prospective Randomized Single-Blind Trial Completed NCT00453830 Phase 4
5 Hartmann vs Resection With Anastomosis and Diverting Stoma for Peritonitis Caused by Perforated Left-sided Colon Diverticulitis: a Multicenter Prospective Randomized Study. Completed NCT01239927 Phase 2, Phase 3
6 Double-blind, Randomised, Placebo-controlled, Parallel-group, Multi-centre Phase III Clinical Study on the Efficacy and Tolerability of Mesalazine Pellets vs. Placebo in Diverticular Disease Completed NCT01627262 Phase 2 Mesalamine;Placebo
7 The Role of Intestinal Microbiota Composition and Intestinal Permeability in the Development of (Complicated) Diverticular Disease. Unknown status NCT01493349
8 Seal-G MIST System Safety Study [SEALAR Study] Unknown status NCT03448874
9 Natural History of Sigmoid Diverticulitis: The Geneva Cohort Study Unknown status NCT01015378
10 Prophylactic Elective Clipping of Colonic Diverticula in Patients Who Have Had Sustained Lower Gastrointestinal Haemorrhage Unknown status NCT02094456
11 Single Port Colic Laparoscopic Surgery - THE TRUE TRIAL Completed NCT01959087
12 Is Antibiotic Therapy Mandatory for Treatment of Uncomplicated Acute Colonic Diverticulitis: a Randomized Clinical Trial Completed NCT01008488 Antibiotic
13 Risk Factors for Colonic Resections in Patients With Suspected Acute Appendicitis Completed NCT00888888
14 Management of Patients With Uncomplicated Diverticulitis as Out-patient and Without Antibiotics Completed NCT01515150
15 Mechanistic Randomized Controlled Trial of Mesalazine in Symptomatic Diverticular Disease Completed NCT00663247 Placebo
16 Diagnostic Accuracy and Role of Bedside Ultrasound in Patients With Suspected Acute Diverticulitis Completed NCT03279588
17 Follow-Up Phone Calls After Colorectal Surgery to Assess Patient Satisfaction and Post-Operative Outcomes Completed NCT00474097
18 Multicentric Point of Care UltraSound by Surgeons Trial Completed NCT02682368
19 Randomized Multicentric Controlled Clinical Trial of Parallel Groups to Evaluate the Non-therapeutic Inferiority of a Free Diet With a Progressive Diet, in the Treatment of Non-complicated Acute Diverticulitis Completed NCT03496090
20 A Randomized Trial Comparing Outcomes for the LigaSure and Disposable Stapling Instruments for Laparoscopic Surgery Completed NCT00487409
21 PREDICtors for Health Related Quality of Life After Elective Sigmoidectomy for DIVerticular Disease: The PREDIC-DIV Study Recruiting NCT03527706
22 Prevalence of Segmental Colitis Associated With Colic Diverticulosis (SCAD): an Observational Study Recruiting NCT04279821
23 Clinical Trial for the Determination of Advanced Colonic Neoplasia Prevalence and the Need for Colonoscopy in Complicated and Uncomplicated Acute Diverticulitis Recruiting NCT03557216
24 A Prospective Randomised Placebo Controlled Trial on Prophylactic Endoscopic Clipping of Colonic Diverticula (PECoD) Recruiting NCT03935100
25 Scandinavian Diverticulitis Trial SCANDIV II: Treatment of Acute Complicated Diverticulitis: a Prospective Observational Study Recruiting NCT04254224
26 Management and Evolution of Acute Diverticulitis With Pericolic Free Gas - a Multicentre Observational Study Recruiting NCT04311385
27 Prospective and Multicentre Study on Clinical-biological Factors Predictive of Chronic Colon DIverticulitis Recruiting NCT04407793
28 Intraoperative Testing of Colorectal Anastomosis - Air or Water (Methylene Blue)? Not yet recruiting NCT03316677

Search NIH Clinical Center for Diverticulitis of Colon

Cochrane evidence based reviews: diverticulitis, colonic

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Genetic Tests for Diverticulitis of Colon

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Anatomical Context for Diverticulitis of Colon

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MalaCards organs/tissues related to Diverticulitis of Colon:

40
Colon, Liver, Testes
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Publications for Diverticulitis of Colon

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Articles related to Diverticulitis of Colon:

(show all 23)
# Title Authors PMID Year
1
Laparoscopic lavage and drainage for Hinchey III diverticulitis: review of technical aspects. 61
30097970 2019
2
Pharmacobezoar: An Unusual Cause of Large Bowel Obstruction. 61
29118874 2017
3
William Arbuthnot Lane (1856-1943): Surgical Innovator and His Theory of Autointoxication. 61
28234103 2017
4
Contemporary Review of Risk-Stratified Management in Acute Uncomplicated and Complicated Diverticulitis. 61
27206400 2016
5
Diverticulosis and Diverticulitis. 61
27156370 2016
6
A comparison of outcomes of emergent, urgent, and elective surgical treatment of diverticulitis. 61
26116319 2015
7
Experience of managing complicated diverticulitis of colon: a retrospective case series from South Asian country. 61
24864634 2014
8
Resection and primary anastomosis in acute complicated diverticulitis, a systematic review of the literature. 61
16437211 2007
9
Long-term treatment with mesalazine and rifaximin versus rifaximin alone for patients with recurrent attacks of acute diverticulitis of colon. 61
12236485 2002
10
[Standardization in sigmoid diverticulitis surgery planning: indications based on evaluation with the Hughes classification]. 61
9574354 1997
11
Unusual cases of perforated diverticulitis of colon. 61
2230705 1990
12
[A case of vesicosigmoidal fistula secondary to diverticulitis of the colon]. 61
3618434 1987
13
Case profile: unique uroradiographic manifestation of diverticulitis of colon. 61
7112836 1982
14
[Colonic localization of Crohn's disease. New case reports. Rectocolic Crohn's disease. Colonic Crohn's disease and sigmoid diverticulitis. Colonic Crohn's disease]. 61
5562841 1971
15
[Diverticulitis, colonic diverticulosis]. 61
5772002 1969
16
GENERALIZED PERITONITIS COMPLICATING ACUTE DIVERTICULITIS OF COLON. 61
14236316 1965
17
Surgical management in complications of diverticulitis of colon. 61
13661559 1959
18
[Diverticulitis of colon]. 61
13375325 1956
19
Diverticulitis of colon and new aspects of its treatment with report of five cases. 61
14393950 1955
20
Surgical treatment of diverticulitis of colon. 61
13227745 1955
21
[Anatomopathological and clinical experiences with stenotic diverticulitis of colon, with special reference to therapeutic problems]. 61
13331051 1955
22
Intestinovesical fistula Report of three cases resulting from diverticulitis of colon. 61
14817551 1951
23
[Clinical aspects of diverticulitis of colon and sigmoid]. 61
14800610 1950
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Variations for Diverticulitis of Colon

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Expression for Diverticulitis of Colon

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Search GEO for disease gene expression data for Diverticulitis of Colon.
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Pathways for Diverticulitis of Colon

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GO Terms for Diverticulitis of Colon

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Sources for Diverticulitis of Colon

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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