HS3
MCID: DNS008
MIFTS: 12

Dna, Satellite, Iii (HS3)

Aliases & Classifications for Dna, Satellite, Iii

MalaCards integrated aliases for Dna, Satellite, Iii:

Name: Dna, Satellite, Iii 57 55
Hs3 57

External Ids:

OMIM 57 126370

Summaries for Dna, Satellite, Iii

MalaCards based summary : Dna, Satellite, Iii, also known as hs3, is related to spherocytosis, type 3 and thalassemia. An important gene associated with Dna, Satellite, Iii is MYC (MYC Proto-Oncogene, BHLH Transcription Factor). The drugs Dexamethasone and Epinephrine have been mentioned in the context of this disorder.

Description from OMIM: 126370

Related Diseases for Dna, Satellite, Iii

Diseases related to Dna, Satellite, Iii via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 spherocytosis, type 3 11.2
2 thalassemia 10.1
3 lymphoma 9.9

Symptoms & Phenotypes for Dna, Satellite, Iii

Clinical features from OMIM:

126370

Drugs & Therapeutics for Dna, Satellite, Iii

Drugs for Dna, Satellite, Iii (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 46)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 2 50-02-2 5743
2
Epinephrine Approved, Vet_approved Phase 4,Phase 2 51-43-4 5816
3
Racepinephrine Approved Phase 4,Phase 2 329-65-7 838
4 Adrenergic Agents Phase 4,Phase 2
5 Adrenergic Agonists Phase 4,Phase 2
6 Adrenergic alpha-Agonists Phase 4,Phase 2
7 Adrenergic beta-Agonists Phase 4,Phase 2
8 Anti-Asthmatic Agents Phase 4,Phase 2
9 Antiemetics Phase 4,Phase 2
10 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2
11 Antineoplastic Agents, Hormonal Phase 4,Phase 2
12 Autonomic Agents Phase 4,Phase 2
13 BB 1101 Phase 4,Phase 2
14 Bronchodilator Agents Phase 4,Phase 2
15 Dexamethasone acetate Phase 4,Phase 2 1177-87-3
16 Epinephryl borate Phase 4,Phase 2
17 Gastrointestinal Agents Phase 4,Phase 2
18 glucocorticoids Phase 4,Phase 2
19 HIV Protease Inhibitors Phase 4,Phase 2
20 Hormone Antagonists Phase 4,Phase 2
21 Hormones Phase 4,Phase 2
22 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 2
23 Mydriatics Phase 4,Phase 2
24 Neurotransmitter Agents Phase 4,Phase 2
25 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2
26 Pharmaceutical Solutions Phase 4,Phase 2,Phase 1
27
protease inhibitors Phase 4,Phase 2
28 Respiratory System Agents Phase 4,Phase 2
29 Vasoconstrictor Agents Phase 4,Phase 2
30
Diclofenac Approved, Vet_approved Phase 3 15307-86-5 3033
31
Lidocaine Approved, Vet_approved Phase 3 137-58-6 3676
32 Analgesics Phase 3,Phase 2
33 Analgesics, Non-Narcotic Phase 3,Phase 2
34 Anesthetics Phase 3
35 Anesthetics, Local Phase 3
36 Anti-Arrhythmia Agents Phase 3
37 Anti-Inflammatory Agents, Non-Steroidal Phase 3,Phase 2
38 Antirheumatic Agents Phase 3,Phase 2
39 Central Nervous System Depressants Phase 3
40 Cyclooxygenase Inhibitors Phase 3
41 Diuretics, Potassium Sparing Phase 3
42 Sodium Channel Blockers Phase 3
43
Benzocaine Approved, Investigational Phase 1, Phase 2 1994-09-7, 94-09-7 2337
44
Curcumin Approved, Investigational Phase 2 458-37-7 969516
45 tannic acid Approved, Nutraceutical Phase 1, Phase 2
46 Arginine Vasopressin

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Epinephrine, Dexamethasone, and Hypertonic Saline in Bronchiolitis, Randomised Clinical Trial of Efficacy and Safety Completed NCT01834820 Phase 4 Epinephrine and Dexamethasone;Hypertonic Saline;Normal Saline
2 Diclofenac Potassium With Lidocaine Cream in Reducing Pain During HSG Completed NCT02709590 Phase 3 diclofenac potassium + lidocaine;placebo
3 Epinephrine, Dexamethasone and Hypertonic Saline in Bronchiolitis Unknown status NCT02585531 Phase 2 Hypertonic Saline 3%;Epinephrine and Dexamethasone
4 Safety and Feasibility of Hypertonic Saline Solution After Aneurysmal Subarachnoid Hemorrhage: Unknown status NCT02432157 Phase 1, Phase 2 HTS 3%;Standard fluid management
5 Micellar Curcumin and Metabolic Syndrome Biomarkers Completed NCT01925547 Phase 2
6 Influence of the Nebulizer on the Clinical Efficacy of Hypertonic Saline 3% in Children Aged Less Than 18 Months and Hospitalized With Acute Viral Bronchiolitis Unknown status NCT01295398 Not Applicable
7 High Sensitive Troponin T (hsTnT) and Copeptin as Prognostic Parameters in Patients With Elective Total Endoprosthesis Unknown status NCT01335815

Search NIH Clinical Center for Dna, Satellite, Iii

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Anatomical Context for Dna, Satellite, Iii

Publications for Dna, Satellite, Iii

Variations for Dna, Satellite, Iii

Expression for Dna, Satellite, Iii

Search GEO for disease gene expression data for Dna, Satellite, Iii.

Pathways for Dna, Satellite, Iii

GO Terms for Dna, Satellite, Iii

Sources for Dna, Satellite, Iii

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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