HS3
MCID: DNS008
MIFTS: 17

Dna, Satellite, Iii (HS3)

Aliases & Classifications for Dna, Satellite, Iii

MalaCards integrated aliases for Dna, Satellite, Iii:

Name: Dna, Satellite, Iii 58 56
Hs3 58

External Ids:

OMIM 58 126370

Summaries for Dna, Satellite, Iii

MalaCards based summary : Dna, Satellite, Iii, also known as hs3, is related to spherocytosis, type 3 and retinoblastoma. An important gene associated with Dna, Satellite, Iii is MYC (MYC Proto-Oncogene, BHLH Transcription Factor). The drugs Racepinephrine and Epinephrine have been mentioned in the context of this disorder. Affiliated tissues include breast.

Description from OMIM: 126370

Related Diseases for Dna, Satellite, Iii

Diseases in the Dna, Satellite, Iii family:

Dna, Satellite, Alpha Type

Diseases related to Dna, Satellite, Iii via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 spherocytosis, type 3 11.4
2 retinoblastoma 10.2
3 thalassemia 10.2

Symptoms & Phenotypes for Dna, Satellite, Iii

Clinical features from OMIM:

126370

Drugs & Therapeutics for Dna, Satellite, Iii

Drugs for Dna, Satellite, Iii (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 47)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Racepinephrine Approved Phase 4,Phase 2 329-65-7 838
2
Epinephrine Approved, Vet_approved Phase 4,Phase 2 51-43-4 5816
3
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4,Phase 2 1177-87-3
4
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 2 50-02-2 5743
5 Mydriatics Phase 4,Phase 2
6 Adrenergic beta-Agonists Phase 4,Phase 2
7 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2
8 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2
9 HIV Protease Inhibitors Phase 4,Phase 2
10 Adrenergic Agonists Phase 4,Phase 2
11 Hormones Phase 4,Phase 2
12
protease inhibitors Phase 4,Phase 2
13 Vasoconstrictor Agents Phase 4,Phase 2
14 Anti-Asthmatic Agents Phase 4,Phase 2
15 Autonomic Agents Phase 4,Phase 2
16 BB 1101 Phase 4,Phase 2
17 Neurotransmitter Agents Phase 4,Phase 2
18 Sympathomimetics Phase 4,Phase 2
19 Adrenergic alpha-Agonists Phase 4,Phase 2
20 Antineoplastic Agents, Hormonal Phase 4,Phase 2
21 Epinephryl borate Phase 4,Phase 2
22 Hormone Antagonists Phase 4,Phase 2
23 Antiemetics Phase 4,Phase 2
24 Bronchodilator Agents Phase 4,Phase 2
25 Adrenergic Agents Phase 4,Phase 2
26 Respiratory System Agents Phase 4,Phase 2
27 Gastrointestinal Agents Phase 4,Phase 2
28 glucocorticoids Phase 4,Phase 2
29 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 2
30 Pharmaceutical Solutions Phase 4,Phase 2,Phase 1
31
Lidocaine Approved, Vet_approved Phase 3 137-58-6 3676
32
Diclofenac Approved, Vet_approved Phase 3 15307-86-5 3033
33 Analgesics, Non-Narcotic Phase 3,Phase 2
34 Antirheumatic Agents Phase 3,Phase 2
35 Diuretics, Potassium Sparing Phase 3
36 Analgesics Phase 3,Phase 2
37 Anti-Inflammatory Agents, Non-Steroidal Phase 3,Phase 2
38 Anesthetics Phase 3
39 Anesthetics, Local Phase 3
40 Sodium Channel Blockers Phase 3
41 Anti-Arrhythmia Agents Phase 3
42 Cyclooxygenase Inhibitors Phase 3
43 Central Nervous System Depressants Phase 3
44
tannic acid Approved Phase 1, Phase 2 1401-55-4
45
Benzocaine Approved, Investigational Phase 1, Phase 2 94-09-7, 1994-09-7 2337
46
Curcumin Approved, Experimental, Investigational Phase 2 458-37-7 969516
47 Arginine Vasopressin

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Epinephrine, Dexamethasone, and Hypertonic Saline in Bronchiolitis, Randomised Clinical Trial of Efficacy and Safety Completed NCT01834820 Phase 4 Epinephrine and Dexamethasone;Hypertonic Saline;Normal Saline
2 Diclofenac Potassium With Lidocaine Cream in Reducing Pain During HSG Completed NCT02709590 Phase 3 diclofenac potassium + lidocaine;placebo
3 Epinephrine, Dexamethasone and Hypertonic Saline in Bronchiolitis Unknown status NCT02585531 Phase 2 Hypertonic Saline 3%;Epinephrine and Dexamethasone
4 Safety and Feasibility of Hypertonic Saline Solution After Aneurysmal Subarachnoid Hemorrhage: Unknown status NCT02432157 Phase 1, Phase 2 HTS 3%;Standard fluid management
5 Micellar Curcumin and Metabolic Syndrome Biomarkers Completed NCT01925547 Phase 2
6 Influence of the Nebulizer on the Clinical Efficacy of Hypertonic Saline 3% in Children Aged Less Than 18 Months and Hospitalized With Acute Viral Bronchiolitis Unknown status NCT01295398 Not Applicable
7 High Sensitive Troponin T (hsTnT) and Copeptin as Prognostic Parameters in Patients With Elective Total Endoprosthesis Unknown status NCT01335815

Search NIH Clinical Center for Dna, Satellite, Iii

Genetic Tests for Dna, Satellite, Iii

Anatomical Context for Dna, Satellite, Iii

MalaCards organs/tissues related to Dna, Satellite, Iii:

42
Breast

Publications for Dna, Satellite, Iii

Articles related to Dna, Satellite, Iii:

(show all 11)
# Title Authors Year
1
O-Antigens of Escherichia coli Strains O81 and HS3-104 Are Structurally and Genetically Related, Except O-Antigen Glucosylation in E. coli HS3-104. ( 29738687 )
2018
2
Dust Impacts on the 2012 Hurricane Nadine Track during the NASA HS3 Field Campaign. ( 30344342 )
2018
3
Towards Polysulfuric Acids: The Hydrogentrisulfate Anion [HS3 O10 ]- in A[HS3 O10 ] (A=Na, K, Rb). ( 27529393 )
2016
4
The plastidic DEAD-box RNA helicase 22, HS3, is essential for plastid functions both in seed development and in seedling growth. ( 23803517 )
2013
5
Yin Yang 1 is a lipopolysaccharide-inducible activator of the murine 3' Igh enhancer, hs3. ( 12759432 )
2003
6
Human satellite 3 (HS3) binding protein from the nuclear matrix: isolation and binding properties. ( 10903425 )
2000
7
Dyad symmetry within the mouse 3' IgH regulatory region includes two virtually identical enhancers (C alpha3'E and hs3). ( 9144492 )
1997
8
Identification of a homolog of the C alpha 3'/hs3 enhancer and of an allelic variant of the 3'IgH/hs1,2 enhancer downstream of the human immunoglobulin alpha 1 gene. ( 9394827 )
1997
9
A modification of the HS3 thoracic Alpha Cradle for breast/chestwall patients. ( 2340083 )
1990
10
Recharacterization of fungal dinucleoside polyphosphate (HS3). ( 647443 )
1978
11
Possible regulation of macromolecular biosynthesis in mammalian cells by a novel dinucleoside polyphosphate (HS3) produced during step-down growth conditions. ( 591567 )
1977

Variations for Dna, Satellite, Iii

Expression for Dna, Satellite, Iii

Search GEO for disease gene expression data for Dna, Satellite, Iii.

Pathways for Dna, Satellite, Iii

GO Terms for Dna, Satellite, Iii

Sources for Dna, Satellite, Iii

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
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45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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