HS3
MCID: DNS008
MIFTS: 11

Dna, Satellite, Iii (HS3)

Aliases & Classifications for Dna, Satellite, Iii

MalaCards integrated aliases for Dna, Satellite, Iii:

Name: Dna, Satellite, Iii 57 55
Hs3 57

External Ids:

OMIM 57 126370

Summaries for Dna, Satellite, Iii

MalaCards based summary : Dna, Satellite, Iii, also known as hs3, is related to spherocytosis, type 3 and retinoblastoma. An important gene associated with Dna, Satellite, Iii is MYC (MYC Proto-Oncogene, BHLH Transcription Factor). The drugs Epinephrine and Dexamethasone acetate have been mentioned in the context of this disorder. Affiliated tissues include breast.

Description from OMIM: 126370

Related Diseases for Dna, Satellite, Iii

Diseases in the Dna, Satellite, Iii family:

Dna, Satellite, Alpha Type

Diseases related to Dna, Satellite, Iii via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 spherocytosis, type 3 11.4
2 retinoblastoma 10.2
3 thalassemia 10.2

Symptoms & Phenotypes for Dna, Satellite, Iii

Clinical features from OMIM:

126370

Drugs & Therapeutics for Dna, Satellite, Iii

Drugs for Dna, Satellite, Iii (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 47)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Epinephrine Approved, Vet_approved Phase 4,Phase 2 51-43-4 5816
2
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4,Phase 2 1177-87-3
3
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 2 50-02-2 5743
4
Racepinephrine Approved Phase 4,Phase 2 329-65-7 838
5 Vasoconstrictor Agents Phase 4,Phase 2
6 Sympathomimetics Phase 4,Phase 2
7 Antineoplastic Agents, Hormonal Phase 4,Phase 2
8
protease inhibitors Phase 4,Phase 2
9 Adrenergic beta-Agonists Phase 4,Phase 2
10 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 2
11 Adrenergic Agonists Phase 4,Phase 2
12 Adrenergic alpha-Agonists Phase 4,Phase 2
13 Antiemetics Phase 4,Phase 2
14 Hormones Phase 4,Phase 2
15 Adrenergic Agents Phase 4,Phase 2
16 Hormone Antagonists Phase 4,Phase 2
17 Epinephryl borate Phase 4,Phase 2
18 glucocorticoids Phase 4,Phase 2
19 Mydriatics Phase 4,Phase 2
20 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2
21 Pharmaceutical Solutions Phase 4,Phase 2,Phase 1
22 Autonomic Agents Phase 4,Phase 2
23 Respiratory System Agents Phase 4,Phase 2
24 BB 1101 Phase 4,Phase 2
25 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2
26 Anti-Asthmatic Agents Phase 4,Phase 2
27 Neurotransmitter Agents Phase 4,Phase 2
28 Gastrointestinal Agents Phase 4,Phase 2
29 HIV Protease Inhibitors Phase 4,Phase 2
30 Bronchodilator Agents Phase 4,Phase 2
31
Diclofenac Approved, Vet_approved Phase 3 15307-86-5 3033
32
Lidocaine Approved, Vet_approved Phase 3 137-58-6 3676
33 Anti-Inflammatory Agents, Non-Steroidal Phase 3,Phase 2
34 Anti-Arrhythmia Agents Phase 3
35 Anesthetics, Local Phase 3
36 Diuretics, Potassium Sparing Phase 3
37 Antirheumatic Agents Phase 3,Phase 2
38 Anesthetics Phase 3
39 Sodium Channel Blockers Phase 3
40 Central Nervous System Depressants Phase 3
41 Cyclooxygenase Inhibitors Phase 3
42 Analgesics, Non-Narcotic Phase 3,Phase 2
43 Analgesics Phase 3,Phase 2
44 tannic acid Approved Phase 1, Phase 2
45
Benzocaine Approved, Investigational Phase 1, Phase 2 94-09-7, 1994-09-7 2337
46
Curcumin Approved, Experimental, Investigational Phase 2 458-37-7 969516
47 Arginine Vasopressin

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Epinephrine, Dexamethasone, and Hypertonic Saline in Bronchiolitis, Randomised Clinical Trial of Efficacy and Safety Completed NCT01834820 Phase 4 Epinephrine and Dexamethasone;Hypertonic Saline;Normal Saline
2 Diclofenac Potassium With Lidocaine Cream in Reducing Pain During HSG Completed NCT02709590 Phase 3 diclofenac potassium + lidocaine;placebo
3 Epinephrine, Dexamethasone and Hypertonic Saline in Bronchiolitis Unknown status NCT02585531 Phase 2 Hypertonic Saline 3%;Epinephrine and Dexamethasone
4 Safety and Feasibility of Hypertonic Saline Solution After Aneurysmal Subarachnoid Hemorrhage: Unknown status NCT02432157 Phase 1, Phase 2 HTS 3%;Standard fluid management
5 Micellar Curcumin and Metabolic Syndrome Biomarkers Completed NCT01925547 Phase 2
6 Influence of the Nebulizer on the Clinical Efficacy of Hypertonic Saline 3% in Children Aged Less Than 18 Months and Hospitalized With Acute Viral Bronchiolitis Unknown status NCT01295398 Not Applicable
7 High Sensitive Troponin T (hsTnT) and Copeptin as Prognostic Parameters in Patients With Elective Total Endoprosthesis Unknown status NCT01335815

Search NIH Clinical Center for Dna, Satellite, Iii

Genetic Tests for Dna, Satellite, Iii

Anatomical Context for Dna, Satellite, Iii

MalaCards organs/tissues related to Dna, Satellite, Iii:

41
Breast

Publications for Dna, Satellite, Iii

Articles related to Dna, Satellite, Iii:

(show all 11)
# Title Authors Year
1
O-Antigens of Escherichia coli Strains O81 and HS3-104 Are Structurally and Genetically Related, Except O-Antigen Glucosylation in E. coli HS3-104. ( 29738687 )
2018
2
Dust Impacts on the 2012 Hurricane Nadine Track during the NASA HS3 Field Campaign. ( 30344342 )
2018
3
Towards Polysulfuric Acids: The Hydrogentrisulfate Anion [HS3 O10 ]- in A[HS3 O10 ] (A=Na, K, Rb). ( 27529393 )
2016
4
The plastidic DEAD-box RNA helicase 22, HS3, is essential for plastid functions both in seed development and in seedling growth. ( 23803517 )
2013
5
Yin Yang 1 is a lipopolysaccharide-inducible activator of the murine 3' Igh enhancer, hs3. ( 12759432 )
2003
6
Human satellite 3 (HS3) binding protein from the nuclear matrix: isolation and binding properties. ( 10903425 )
2000
7
Dyad symmetry within the mouse 3' IgH regulatory region includes two virtually identical enhancers (C alpha3'E and hs3). ( 9144492 )
1997
8
Identification of a homolog of the C alpha 3'/hs3 enhancer and of an allelic variant of the 3'IgH/hs1,2 enhancer downstream of the human immunoglobulin alpha 1 gene. ( 9394827 )
1997
9
A modification of the HS3 thoracic Alpha Cradle for breast/chestwall patients. ( 2340083 )
1990
10
Recharacterization of fungal dinucleoside polyphosphate (HS3). ( 647443 )
1978
11
Possible regulation of macromolecular biosynthesis in mammalian cells by a novel dinucleoside polyphosphate (HS3) produced during step-down growth conditions. ( 591567 )
1977

Variations for Dna, Satellite, Iii

Expression for Dna, Satellite, Iii

Search GEO for disease gene expression data for Dna, Satellite, Iii.

Pathways for Dna, Satellite, Iii

GO Terms for Dna, Satellite, Iii

Sources for Dna, Satellite, Iii

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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