MCID: DCK001
MIFTS: 6

Dock2 Deficiency

Categories: Rare diseases

Aliases & Classifications for Dock2 Deficiency

MalaCards integrated aliases for Dock2 Deficiency:

Name: Dock2 Deficiency 54

Classifications:



Summaries for Dock2 Deficiency

MalaCards based summary : Dock2 Deficiency is related to immunodeficiency 40. An important gene associated with Dock2 Deficiency is DOCK2 (Dedicator Of Cytokinesis 2). Affiliated tissues include neutrophil.

Related Diseases for Dock2 Deficiency

Diseases related to Dock2 Deficiency via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 immunodeficiency 40 11.6

Symptoms & Phenotypes for Dock2 Deficiency

Drugs & Therapeutics for Dock2 Deficiency

Search Clinical Trials , NIH Clinical Center for Dock2 Deficiency

Genetic Tests for Dock2 Deficiency

Anatomical Context for Dock2 Deficiency

MalaCards organs/tissues related to Dock2 Deficiency:

42
Neutrophil

Publications for Dock2 Deficiency

Articles related to Dock2 Deficiency:

# Title Authors Year
1
Human DOCK2 Deficiency: Report of a Novel Mutation and Evidence for Neutrophil Dysfunction. ( 30838481 )
2019
2
DOCK2 Deficiency in a Patient with Hyper IgM Phenotype. ( 29204803 )
2018
3
DOCK2 deficiency mitigates HFD-induced obesity by reducing adipose tissue inflammation and increasing energy expenditure. ( 28716822 )
2017
4
Inherited DOCK2 Deficiency in Patients with Early-Onset Invasive Infections. ( 26083206 )
2015

Variations for Dock2 Deficiency

Expression for Dock2 Deficiency

Search GEO for disease gene expression data for Dock2 Deficiency.

Pathways for Dock2 Deficiency

GO Terms for Dock2 Deficiency

Sources for Dock2 Deficiency

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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