GWD
MCID: DRC001
MIFTS: 39

Dracunculiasis (GWD)

Categories: Infectious diseases, Rare diseases

Aliases & Classifications for Dracunculiasis

MalaCards integrated aliases for Dracunculiasis:

Name: Dracunculiasis 12 76 53 59 3 44 15 73
Guinea Worm Disease 53 59 3
Parasitic Infection Caused by Dracunculus Medinensis 53
Infection by Dracunculus Medinensis 12
Guinea Worm Infection 53
Medina Worm Disease 59
Dracunculosis 59
Dracontiasis 12
Medinensis 59
Gwd 53

Characteristics:

Orphanet epidemiological data:

59
dracunculiasis
Age of onset: All ages; Age of death: any age;

Classifications:

Orphanet: 59  
Rare infectious diseases


External Ids:

Disease Ontology 12 DOID:14418
ICD10 33 B72
ICD9CM 35 125.7
MeSH 44 D004320
NCIt 50 C84677
SNOMED-CT 68 48874008
Orphanet 59 ORPHA231
UMLS via Orphanet 74 C0013100
ICD10 via Orphanet 34 B72
MESH via Orphanet 45 D004320
UMLS 73 C0013100

Summaries for Dracunculiasis

Disease Ontology : 12 A parasitic helminthiasis infectious disease that involves parasitic infection by the larvae of the nematode Dracunculus medinensis, which are transmitted to humans by drinking water containing copepods infected with the larvae. The female, which contains larvae, burrows into the deeper connective tissues or adjacent to long bones or joints of the extremities. The worm emerges as a whitish filament in the center of a painful ulcer, accompanied by inflammation and frequently by secondary bacterial infection.

MalaCards based summary : Dracunculiasis, also known as guinea worm disease, is related to schistosomiasis and onchocerciasis. An important gene associated with Dracunculiasis is SETDB1 (SET Domain Bifurcated 1). Affiliated tissues include skin, bone and breast, and related phenotypes are nausea and vomiting and arthritis

CDC : 3 The program has made great strides from 3.5 million cases annually in the mid-1980s to 25 human cases in 2016. Global eradication is within reach.

Wikipedia : 76 Dracunculiasis, also called Guinea-worm disease (GWD), is an infection by the Guinea worm. A person... more...

Related Diseases for Dracunculiasis

Diseases related to Dracunculiasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 19)
# Related Disease Score Top Affiliating Genes
1 schistosomiasis 10.3
2 onchocerciasis 10.2
3 smallpox 10.2
4 trachoma 10.1
5 poliomyelitis 10.1
6 leiomyoma 10.1
7 pleurisy 10.1
8 intestinal volvulus 10.1
9 malaria 10.0
10 tungiasis 10.0
11 trichuriasis 10.0
12 typhoid fever 10.0
13 yellow fever 10.0
14 filariasis 10.0
15 filarial elephantiasis 10.0
16 dermatitis 10.0
17 parasitic helminthiasis infectious disease 10.0
18 urinary tract obstruction 10.0
19 inappropriate adh syndrome 9.9 AVPR2 SNAI1

Graphical network of the top 20 diseases related to Dracunculiasis:



Diseases related to Dracunculiasis

Symptoms & Phenotypes for Dracunculiasis

Human phenotypes related to Dracunculiasis:

59 32 (show all 15)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 nausea and vomiting 59 32 hallmark (90%) Very frequent (99-80%) HP:0002017
2 arthritis 59 32 frequent (33%) Frequent (79-30%) HP:0001369
3 flexion contracture 59 32 occasional (7.5%) Occasional (29-5%) HP:0001371
4 subcutaneous nodule 59 32 hallmark (90%) Very frequent (99-80%) HP:0001482
5 abnormal blistering of the skin 59 32 hallmark (90%) Very frequent (99-80%) HP:0008066
6 pruritus 59 32 hallmark (90%) Very frequent (99-80%) HP:0000989
7 limitation of joint mobility 59 32 frequent (33%) Frequent (79-30%) HP:0001376
8 skin ulcer 59 32 hallmark (90%) Very frequent (99-80%) HP:0200042
9 diarrhea 59 32 hallmark (90%) Very frequent (99-80%) HP:0002014
10 skin rash 59 32 hallmark (90%) Very frequent (99-80%) HP:0000988
11 cellulitis 59 32 frequent (33%) Frequent (79-30%) HP:0100658
12 recurrent cutaneous abscess formation 59 32 frequent (33%) Frequent (79-30%) HP:0100838
13 gangrene 59 32 occasional (7.5%) Occasional (29-5%) HP:0100758
14 immunologic hypersensitivity 59 32 frequent (33%) Frequent (79-30%) HP:0100326
15 low-grade fever 59 32 hallmark (90%) Very frequent (99-80%) HP:0011134

Drugs & Therapeutics for Dracunculiasis

Search Clinical Trials , NIH Clinical Center for Dracunculiasis

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: dracunculiasis

Genetic Tests for Dracunculiasis

Anatomical Context for Dracunculiasis

MalaCards organs/tissues related to Dracunculiasis:

41
Skin, Bone, Breast, Testes, Spinal Cord

Publications for Dracunculiasis

Articles related to Dracunculiasis:

(show top 50) (show all 386)
# Title Authors Year
1
Dracunculiasis Eradication: Are We There Yet? ( 29869608 )
2018
2
Slaying little dragons: the impact of the Guinea Worm Eradication Program on dracunculiasis disability averted from 1990 to 2016. ( 30234196 )
2018
3
Progress Toward Global Eradication of Dracunculiasis - January 2017-June 2018. ( 30439874 )
2018
4
African Countries Move Closer to Eradicating Guinea Worm Disease. ( 29362803 )
2018
5
New challenges to eradicating Guinea worm disease. ( 30064676 )
2018
6
A mathematical study to control Guinea worm disease: a case study on Chad. ( 30325272 )
2018
7
Dracunculiasis eradication: global surveillance summary, 2016. ( 28530374 )
2017
8
Progress Toward Global Eradication of Dracunculiasis, January 2016-June 2017. ( 29216028 )
2017
9
The painting of St. Roch in the picture gallery of Bari (15th century): An ancient representation of dracunculiasis? ( 28189713 )
2017
10
Zero Cases of Guinea Worm Disease in Mali. ( 28324099 )
2017
11
Recurrence of Guinea Worm Disease in Chad after a 10-Year Absence: Risk Factors for Human Cases Identified in 2010-2011. ( 28722616 )
2017
12
A Multiscale Model for the World's First Parasitic Disease Targeted for Eradication: Guinea Worm Disease. ( 28808479 )
2017
13
Elimination of Guinea Worm Disease in Ethiopia; Current Status of the Disease's, Eradication Strategies and Challenges to the End Game. ( 28878428 )
2017
14
The cost-effectiveness of an eradication programme in the end game: Evidence from guinea worm disease. ( 28981510 )
2017
15
WHO delays guinea-worm disease eradication to 2020: are dogs the sole culprits? ( 29115265 )
2017
16
Smallpox and Dracunculiasis: The Scientific Value of Infectious Diseases That Have Been Eradicated or Targeted for Eradication. Is Schistosomiasis Next? ( 26741130 )
2016
17
Progress Toward Global Eradication of Dracunculiasis -January 2015-June 2016. ( 27736840 )
2016
18
Dracunculiasis eradication: global surveillance summary, 2015. ( 27132287 )
2016
19
Dracunculiasis in oral and maxillofacial surgery. ( 27162746 )
2016
20
Guinea worm disease nears eradication. ( 26867453 )
2016
21
Monthly report on dracunculiasis cases, Januarya89November 2014. ( 25671847 )
2015
22
Monthly report on dracunculiasis cases, January-May 2015. ( 26121769 )
2015
23
Monthly report on dracunculiasis cases, Januarya89 February 2015. ( 25958418 )
2015
24
Monthly report on dracunculiasis cases, January-April 2015. ( 26027017 )
2015
25
Progress Toward Global Eradication of Dracunculiasis, January 2014-June 2015. ( 26492134 )
2015
26
Monthly report on dracunculiasis cases, January-July 2015. ( 26454889 )
2015
27
Monthly report on dracunculiasis cases, January-June 2015. ( 26298884 )
2015
28
Monthly report on dracunculiasis cases, Januarya89December 2014. ( 25702332 )
2015
29
Dracunculiasis eradication: global surveillance summary, 2014. ( 25958417 )
2015
30
Monthly report on dracunculiasis cases, January- September 2015. ( 26591027 )
2015
31
Monthly report on dracunculiasis cases, January-October 2015. ( 26685392 )
2015
32
Monthly report on dracunculiasis cases, January 2014. ( 24707516 )
2014
33
Progress toward global eradication of dracunculiasis--January 2013-June 2014. ( 25412061 )
2014
34
Monthly report on dracunculiasis cases, Januarya89November 2013. ( 24446560 )
2014
35
Monthly report on dracunculiasis cases, Januarya89July 2014. ( 25184187 )
2014
36
Guinea worm (Dracunculiasis) eradication: update on progress and endgame challenges. ( 24699360 )
2014
37
Monthly report on dracunculiasis cases, Januarya89February 2014. ( 24707536 )
2014
38
Monthly report on dracunculiasis cases, Januarya89June 2014. ( 25136722 )
2014
39
Dracunculiasis eradication--global surveillance summary, 2013. ( 24864343 )
2014
40
The peculiar epidemiology of dracunculiasis in chad. ( 24277785 )
2014
41
Monthly report on dracunculiasis cases, January a89- April 2014. ( 24864344 )
2014
42
An experience with dracunculiasis in Melbourne, Australia. ( 25393260 )
2014
43
Monthly report on dracunculiasis cases, Januarya89December 2013. ( 24707512 )
2014
44
Monthly report on dracunculiasis cases, Januarya89August 2014. ( 25313424 )
2014
45
Monthly report on dracunculiasis cases, Januarya89May 2014. ( 25028755 )
2014
46
Monthly report on dracunculiasis cases, Januarya89October 2014. ( 25538996 )
2014
47
The last bastions of guinea-worm disease. ( 25552768 )
2014
48
Global eradication of guinea worm disease: Toward a newer milestone. ( 25709667 )
2014
49
Logistics of Guinea worm disease eradication in South Sudan. ( 24445199 )
2014
50
Monthly report on dracunculiasis cases, Januarya89November 2012. ( 23393705 )
2013

Variations for Dracunculiasis

Expression for Dracunculiasis

Search GEO for disease gene expression data for Dracunculiasis.

Pathways for Dracunculiasis

GO Terms for Dracunculiasis

Sources for Dracunculiasis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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