MCID: DRC001
MIFTS: 40

Dracunculiasis

Categories: Rare diseases, Infectious diseases

Aliases & Classifications for Dracunculiasis

MalaCards integrated aliases for Dracunculiasis:

Name: Dracunculiasis 12 76 53 59 3 44 15 73
Guinea Worm Disease 53 59 3
Parasitic Infection Caused by Dracunculus Medinensis 53
Infection by Dracunculus Medinensis 12
Guinea Worm Infection 53
Medina Worm Disease 59
Dracunculosis 59
Dracontiasis 12
Medinensis 59
Gwd 53

Characteristics:

Orphanet epidemiological data:

59
dracunculiasis
Age of onset: All ages; Age of death: any age;

Classifications:

Orphanet: 59  
Rare infectious diseases


External Ids:

Disease Ontology 12 DOID:14418
ICD10 33 B72
ICD9CM 35 125.7
MeSH 44 D004320
NCIt 50 C84677
SNOMED-CT 68 396334002 48874008
Orphanet 59 ORPHA231
UMLS via Orphanet 74 C0013100
ICD10 via Orphanet 34 B72
MESH via Orphanet 45 D004320
UMLS 73 C0013100

Summaries for Dracunculiasis

Disease Ontology : 12 A parasitic helminthiasis infectious disease that involves parasitic infection by the larvae of the nematode Dracunculus medinensis, which are transmitted to humans by drinking water containing copepods infected with the larvae. The female, which contains larvae, burrows into the deeper connective tissues or adjacent to long bones or joints of the extremities. The worm emerges as a whitish filament in the center of a painful ulcer, accompanied by inflammation and frequently by secondary bacterial infection.

MalaCards based summary : Dracunculiasis, also known as guinea worm disease, is related to schistosomiasis and onchocerciasis. An important gene associated with Dracunculiasis is SETDB1 (SET Domain Bifurcated 1). Affiliated tissues include skin, bone and breast, and related phenotypes are skin rash and pruritus

CDC : 3 The program has made great strides from 3.5 million cases annually in the mid-1980s to 25 human cases in 2016. Global eradication is within reach.

Wikipedia : 76 Dracunculiasis, also called Guinea-worm disease (GWD), is an infection by the Guinea worm. A person... more...

Related Diseases for Dracunculiasis

Diseases related to Dracunculiasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 19)
# Related Disease Score Top Affiliating Genes
1 schistosomiasis 10.1
2 onchocerciasis 10.0
3 smallpox 10.0
4 trachoma 10.0
5 pleurisy 9.9
6 malaria 9.9
7 tungiasis 9.9
8 trichuriasis 9.9
9 typhoid fever 9.9
10 yellow fever 9.9
11 filariasis 9.8
12 filarial elephantiasis 9.8
13 ancylostomiasis 9.8
14 urethritis 9.8
15 dermatitis 9.8
16 poliomyelitis 9.8
17 parasitic helminthiasis infectious disease 9.8
18 ankylostomiasis 9.8
19 inappropriate adh syndrome 9.8 AVPR2 SNAI1

Graphical network of the top 20 diseases related to Dracunculiasis:



Diseases related to Dracunculiasis

Symptoms & Phenotypes for Dracunculiasis

Human phenotypes related to Dracunculiasis:

59 32 (show all 15)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 skin rash 59 32 hallmark (90%) Very frequent (99-80%) HP:0000988
2 pruritus 59 32 hallmark (90%) Very frequent (99-80%) HP:0000989
3 arthritis 59 32 frequent (33%) Frequent (79-30%) HP:0001369
4 flexion contracture 59 32 occasional (7.5%) Occasional (29-5%) HP:0001371
5 limitation of joint mobility 59 32 frequent (33%) Frequent (79-30%) HP:0001376
6 subcutaneous nodule 59 32 hallmark (90%) Very frequent (99-80%) HP:0001482
7 diarrhea 59 32 hallmark (90%) Very frequent (99-80%) HP:0002014
8 nausea and vomiting 59 32 hallmark (90%) Very frequent (99-80%) HP:0002017
9 abnormal blistering of the skin 59 32 hallmark (90%) Very frequent (99-80%) HP:0008066
10 low-grade fever 59 32 hallmark (90%) Very frequent (99-80%) HP:0011134
11 immunologic hypersensitivity 59 32 frequent (33%) Frequent (79-30%) HP:0100326
12 cellulitis 59 32 frequent (33%) Frequent (79-30%) HP:0100658
13 gangrene 59 32 occasional (7.5%) Occasional (29-5%) HP:0100758
14 recurrent cutaneous abscess formation 59 32 frequent (33%) Frequent (79-30%) HP:0100838
15 skin ulcer 59 32 hallmark (90%) Very frequent (99-80%) HP:0200042

Drugs & Therapeutics for Dracunculiasis

Search Clinical Trials , NIH Clinical Center for Dracunculiasis

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: dracunculiasis

Genetic Tests for Dracunculiasis

Anatomical Context for Dracunculiasis

MalaCards organs/tissues related to Dracunculiasis:

41
Skin, Bone, Breast, Testes, Spinal Cord

Publications for Dracunculiasis

Articles related to Dracunculiasis:

(show top 50) (show all 325)
# Title Authors Year
1
Dracunculiasis Eradication: Are We There Yet? ( 29869608 )
2018
2
Dracunculiasis eradication: global surveillance summary, 2016. ( 28530374 )
2017
3
Progress Toward Global Eradication of Dracunculiasis, January 2016-June 2017. ( 29216028 )
2017
4
The painting of St. Roch in the picture gallery of Bari (15th century): An ancient representation of dracunculiasis? ( 28189713 )
2017
5
Smallpox and Dracunculiasis: The Scientific Value of Infectious Diseases That Have Been Eradicated or Targeted for Eradication. Is Schistosomiasis Next? ( 26741130 )
2016
6
Progress Toward Global Eradication of Dracunculiasis -January 2015-June 2016. ( 27736840 )
2016
7
Dracunculiasis eradication: global surveillance summary, 2015. ( 27132287 )
2016
8
Dracunculiasis in oral and maxillofacial surgery. ( 27162746 )
2016
9
Monthly report on dracunculiasis cases, Januarya89November 2014. ( 25671847 )
2015
10
Monthly report on dracunculiasis cases, January-May 2015. ( 26121769 )
2015
11
Monthly report on dracunculiasis cases, Januarya89 February 2015. ( 25958418 )
2015
12
Monthly report on dracunculiasis cases, January-April 2015. ( 26027017 )
2015
13
Progress Toward Global Eradication of Dracunculiasis, January 2014-June 2015. ( 26492134 )
2015
14
Monthly report on dracunculiasis cases, January-July 2015. ( 26454889 )
2015
15
Monthly report on dracunculiasis cases, January-June 2015. ( 26298884 )
2015
16
Monthly report on dracunculiasis cases, Januarya89December 2014. ( 25702332 )
2015
17
Dracunculiasis eradication: global surveillance summary, 2014. ( 25958417 )
2015
18
Monthly report on dracunculiasis cases, January- September 2015. ( 26591027 )
2015
19
Monthly report on dracunculiasis cases, January-October 2015. ( 26685392 )
2015
20
Monthly report on dracunculiasis cases, January 2014. ( 24707516 )
2014
21
Progress toward global eradication of dracunculiasis--January 2013-June 2014. ( 25412061 )
2014
22
Monthly report on dracunculiasis cases, Januarya89November 2013. ( 24446560 )
2014
23
Monthly report on dracunculiasis cases, Januarya89July 2014. ( 25184187 )
2014
24
Guinea worm (Dracunculiasis) eradication: update on progress and endgame challenges. ( 24699360 )
2014
25
Monthly report on dracunculiasis cases, Januarya89February 2014. ( 24707536 )
2014
26
Monthly report on dracunculiasis cases, Januarya89June 2014. ( 25136722 )
2014
27
Dracunculiasis eradication--global surveillance summary, 2013. ( 24864343 )
2014
28
The peculiar epidemiology of dracunculiasis in chad. ( 24277785 )
2014
29
Monthly report on dracunculiasis cases, January a89- April 2014. ( 24864344 )
2014
30
An experience with dracunculiasis in Melbourne, Australia. ( 25393260 )
2014
31
Monthly report on dracunculiasis cases, Januarya89December 2013. ( 24707512 )
2014
32
Monthly report on dracunculiasis cases, Januarya89August 2014. ( 25313424 )
2014
33
Monthly report on dracunculiasis cases, Januarya89May 2014. ( 25028755 )
2014
34
Monthly report on dracunculiasis cases, Januarya89October 2014. ( 25538996 )
2014
35
Monthly report on dracunculiasis cases, Januarya89November 2012. ( 23393705 )
2013
36
Monthly report on dracunculiasis cases, Januarya89June 2013. ( 24040692 )
2013
37
Progress toward global eradication of dracunculiasis--January 2012-June 2013. ( 24153313 )
2013
38
Dracunculiasis eradication: and now, South Sudan. ( 23843492 )
2013
39
Monthly report on dracunculiasis cases, January - July 2013. ( 24143843 )
2013
40
Monthly report on dracunculiasis cases, January a89 August 2013. ( 24159669 )
2013
41
Monthly report on dracunculiasis cases, Januarya89September 2013. ( 24319785 )
2013
42
Monthly report on dracunculiasis cases, Januarya89December 2012. ( 23540052 )
2013
43
Monthly report on dracunculiasis cases, January a89 March 2013. ( 23696982 )
2013
44
Monthly report on dracunculiasis cases, January a89- May 2013. ( 23980291 )
2013
45
Monthly report on dracunculiasis cases, Januarya89April 2013. ( 23807971 )
2013
46
Dracunculiasis (guinea worm disease): eradication without a drug or a vaccine. ( 23798694 )
2013
47
Monthly report on dracunculiasis cases, January a89 February 2013. ( 23586140 )
2013
48
Monthly report on dracunculiasis cases, January 2013 a89 first month with zero cases. ( 23544240 )
2013
49
Dracunculiasis eradication a89 global surveillance summary, 2012. ( 23696981 )
2013
50
Monthly report on dracunculiasis cases, Januarya89October 2013. ( 24436997 )
2013

Variations for Dracunculiasis

Expression for Dracunculiasis

Search GEO for disease gene expression data for Dracunculiasis.

Pathways for Dracunculiasis

GO Terms for Dracunculiasis

Biological processes related to Dracunculiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein homotetramerization GO:0051289 8.62 HM13 SAMHD1

Sources for Dracunculiasis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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