MCID: DRG022
MIFTS: 6

Drug Metabolism, Altered, Cyp2c8-Related

Categories: Genetic diseases, Metabolic diseases

Aliases & Classifications for Drug Metabolism, Altered, Cyp2c8-Related

MalaCards integrated aliases for Drug Metabolism, Altered, Cyp2c8-Related:

Name: Drug Metabolism, Altered, Cyp2c8-Related 57 6

Classifications:



External Ids:

OMIM 57 618018

Summaries for Drug Metabolism, Altered, Cyp2c8-Related

OMIM : 57 CYP2C8 is involved in the metabolism of a multitude of chemically diverse medications, including nonsteroidal antiinflammatory drugs, thiazolidinediones, and chemotherapeutic agents (summary by Zhou et al., 2017). Backman et al. (2016) reviewed the role of CYP2C8 in clinically relevant drug interactions. (618018)

MalaCards based summary : Drug Metabolism, Altered, Cyp2c8-Related An important gene associated with Drug Metabolism, Altered, Cyp2c8-Related is CYP2C8 (Cytochrome P450 Family 2 Subfamily C Member 8).

Related Diseases for Drug Metabolism, Altered, Cyp2c8-Related

Symptoms & Phenotypes for Drug Metabolism, Altered, Cyp2c8-Related

Clinical features from OMIM:

618018

Drugs & Therapeutics for Drug Metabolism, Altered, Cyp2c8-Related

Search Clinical Trials , NIH Clinical Center for Drug Metabolism, Altered, Cyp2c8-Related

Genetic Tests for Drug Metabolism, Altered, Cyp2c8-Related

Anatomical Context for Drug Metabolism, Altered, Cyp2c8-Related

Publications for Drug Metabolism, Altered, Cyp2c8-Related

Variations for Drug Metabolism, Altered, Cyp2c8-Related

ClinVar genetic disease variations for Drug Metabolism, Altered, Cyp2c8-Related:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 CYP2C8 CYP2C8*5 deletion Pathogenic GRCh38 Chromosome 10, 95067214: 95067214
2 CYP2C8 CYP2C8*5 deletion Pathogenic GRCh37 Chromosome 10, 96826971: 96826971

Expression for Drug Metabolism, Altered, Cyp2c8-Related

Search GEO for disease gene expression data for Drug Metabolism, Altered, Cyp2c8-Related.

Pathways for Drug Metabolism, Altered, Cyp2c8-Related

GO Terms for Drug Metabolism, Altered, Cyp2c8-Related

Sources for Drug Metabolism, Altered, Cyp2c8-Related

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
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31 HMDB
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62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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