Dumping Syndrome disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: DMP001 MIFTS: 47	Dumping Syndrome Categories: Gastrointestinal diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs Expand all tables

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Aliases & Classifications for Dumping Syndrome

MalaCards integrated aliases for Dumping Syndrome:

Name: Dumping Syndrome ¹² ⁵⁵ ⁴⁴ ¹⁵ ⁷³

Dumping ⁵⁵ ⁷³

Postgastrectomy Syndromes ⁷³

Dumping Syndrome ¹²

Jejunal Syndrome ¹²

Classifications:

MalaCards categories:
Anatomical: Gastrointestinal diseases

See all MalaCards categories (disease lists)

ICD10: ³³

Diseases of the digestive system

Other diseases of the digestive system

Postprocedural disorders of digestive system, not elsewhere classified

Postgastric surgery syndromes

External Ids:

Disease Ontology ¹² DOID:14495

ICD10 ³³ K91.1

MeSH ⁴⁴ D004377

NCIt ⁵⁰ C2994

SNOMED-CT ⁶⁸ 80193009

UMLS ⁷³ C0013288 C0032763 C0221542

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Summaries for Dumping Syndrome

MalaCards based summary : Dumping Syndrome, also known as dumping, is related to hyperinsulinemic hypoglycemia and duodenal ulcer, and has symptoms including constipation, pain, postoperative and postoperative nausea and vomiting. An important gene associated with Dumping Syndrome is SST (Somatostatin), and among its related pathways/superpathways are Signaling by GPCR and Peptide ligand-binding receptors. The drugs Somatostatin and lanreotide have been mentioned in the context of this disorder. Affiliated tissues include small intestine, testes and lymph node.

Wikipedia : ⁷⁶ Dumping syndrome occurs when food, especially sugar, moves too quickly from the stomach to the... more...

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Related Diseases for Dumping Syndrome

Diseases related to Dumping Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 85)

#	Related Disease	Score	Top Affiliating Genes
1	hyperinsulinemic hypoglycemia	29.9	INS SST
2	duodenal ulcer	29.8	INS SCT SST
3	gastroesophageal reflux	29.7	GCG NTS PYY
4	constipation	29.6	NTS PYY SST
5	insulinoma	29.4	GCG INS SCT SST
6	duodenogastric reflux	29.3	NTS PYY SCT SST
7	degos 'en cocarde' erythrokeratoderma	10.3
8	hypoglycemia	10.3
9	diarrhea	10.1
10	type 1 diabetes mellitus 15	10.1	GCG INS
11	hyperinsulinemic hypoglycemia, familial, 7	10.1	GCG INS
12	maturity-onset diabetes of the young, type 9	10.1	GCG INS
13	hirata disease	10.1	GCG INS
14	acute insulin response	10.1	GCG INS
15	pancreatoblastoma	10.1	NTS SST
16	prediabetes syndrome	10.1	GCG INS
17	space motion sickness	10.1	NTS SCT
18	duodenal somatostatinoma	10.1	INS SST
19	somatostatinoma	10.1	INS SST
20	postural hypotension	10.1	INS SST
21	pancreatic endocrine carcinoma	10.1	INS SST
22	gastric cancer	10.1
23	peptic ulcer disease	10.1
24	hyperproinsulinemia	10.1	INS SCT
25	hyperpituitarism	10.1	INS SST
26	functional gastric disease	10.1	INS SST
27	glucagonoma	10.1	SCT SST
28	islet cell tumor	10.1	INS SST
29	angiodysplasia	10.1	SCT SST
30	pituitary-dependent cushing's disease	10.0	INS SST
31	maturity-onset diabetes of the young, type 7	10.0	INS SCT
32	duodenal disease	10.0	SCT SST
33	duodenal gastrinoma	10.0	SCT SST
34	endocrine organ benign neoplasm	10.0	INS SST
35	steatorrhea	10.0	SCT SST
36	thyroid gland disease	10.0	INS SST
37	pituitary gland disease	10.0	INS SST
38	cell type benign neoplasm	10.0	INS SST
39	gallbladder disease	10.0	INS SST
40	small intestine cancer	10.0	SCT SST
41	acromegaly	10.0	INS SST
42	hyperthyroidism	10.0	INS SST
43	pneumatosis cystoides intestinalis	10.0	PYY SST
44	microvascular complications of diabetes 1	10.0	INS SST
45	congenital microgastria	10.0
46	serotonin syndrome	10.0	PYY SST
47	insulin-like growth factor i	10.0	INS SST
48	endocrine gland cancer	10.0	GCG SST
49	neuroendocrine tumor	10.0	NTS SST
50	acute pancreatitis	10.0	SCT SST

Graphical network of the top 20 diseases related to Dumping Syndrome:

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Symptoms & Phenotypes for Dumping Syndrome

UMLS symptoms related to Dumping Syndrome:

constipation, pain, postoperative, postoperative nausea and vomiting, vomiting following gastrointestinal surgery

Sources

Drugs & Therapeutics for Dumping Syndrome

Drugs for Dumping Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 32)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Somatostatin

Approved, Investigational

Phase 4,Phase 2,Not Applicable

51110-01-1, 38916-34-6

53481605

lanreotide

Approved

Phase 4,Phase 2

108736-35-2

Pasireotide

Approved

Phase 4,Phase 2

396091-73-9

9941444

Lactitol

Investigational

Phase 4

585-86-4

3871

Synonyms:

(2S,3R,4R,5R)-4-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}hexane-1,2,3,5,6-pentol

4-O-a-D-Glucopyranosyl-D-glucitol

4-O-alpha-delta-Glucopyranosyl-delta-glucitol

4-O-alpha-D-Glucopyranosyl-D-glucitol

4-O-α-D-glucopyranosyl-D-glucitol

a-D-GLC-(1->4)-D-GLC-ol

a-D-GLCP-(1->4)-D-GLC-ol

a-D-Glucosyl-(1->4)-D-glucitol

alpha-D-GLC-(1->4)-D-GLC-ol

alpha-D-GLCP-(1->4)-D-GLC-ol

alpha-D-Glucosyl-(1->4)-D-glucitol

Amalti syrup

Amalty MR 100

D-4-O-alpha-D-Glucopyranosylglucitol

delta-4-O-alpha-delta-Glucopyranosylglucitol

delta-Maltitol

D-Maltitol

lactitol

Malbit

Malti MR

Maltisorb

Maltit

α-D-GLC-(1->4)-D-GLC-ol

α-D-GLCP-(1->4)-D-GLC-ol

α-D-glucosyl-(1->4)-D-glucitol

Angiopeptin

Phase 4,Phase 2

Hormones

Phase 4,Phase 2,Not Applicable

Hormone Antagonists

Phase 4,Phase 2,Not Applicable

Hormones, Hormone Substitutes, and Hormone Antagonists

Phase 4,Phase 2,Not Applicable

Pharmaceutical Solutions

Phase 2

Empagliflozin

Approved

Not Applicable

864070-44-0

Loperamide

Approved

Not Applicable

53179-11-6

3955

Synonyms:

2-methoxyethyl1-methylethyl2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

34552-83-5 (mono-hydrochloride)

4-(4-Chlorophenyl)-N,N-dimethyl-.alpha.,.alpha.-diphenyl-4-hydroxy-1-piperidinebutanamide

4-(4-Chlorophenyl)-N,N-dimethyl-alpha,alpha-diphenyl-4-hydroxy-1-piperidinebutanamide

4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide

5-21-02-00379 (Beilstein Handbook Reference)

53179-11-6

AB00053697

AC1L1H38

AKOS000573892

apo-Loperamide

Apo-Loperamide

BAS 01889668

Bio1_000082

Bio1_000571

Bio1_001060

Bio2_000101

Bio2_000581

BPBio1_000274

BRD-K61250553-001-02-9

BRD-K61250553-003-05-8

BRN 1558273

BSPBio_000248

BSPBio_001381

BSPBio_002769

C07080

C29H33ClN2O2

CAS-34552-83-5

CBiol_001796

CHEBI:162259

CHEBI:6532

CHEMBL841

CID3955

D08144

DB00836

Diamide (TN)

Diarr-Eze

DivK1c_000215

EINECS 258-416-5

HMS1791F03

HMS1989F03

HMS2089C13

Hydrochloride, loperamide

IDI1_000215

IDI1_033851

Imodium

Imodium a-D

Imodium a-D caplets

Imodium A-D Caplets

Ioperamide

Kaopectate II

KBio1_000215

KBio2_000101

KBio2_000854

KBio2_002669

KBio2_003422

KBio2_005237

KBio2_005990

KBio3_000201

KBio3_000202

KBio3_001989

KBioGR_000101

KBioGR_001685

KBioSS_000101

KBioSS_000854

L000709

Lopac0_000708

Lopac-L-4762

Loperacap

Loperamid

Loperamida

Loperamida [INN-Spanish]

loperamide

Lopéramide

Loperamide (INN)

Loperamide [INN:BAN]

Loperamide hydrochloride

Loperamide monohydrochloride

Loperamide Monohydrochloride

Loperamidum

Loperamidum [INN-Latin]

LS-114352

Maalox anti-diarrheal

Maalox Anti-Diarrheal

MolPort-001-969-016

Monohydrochloride, loperamide

NCGC00015608-01

NCGC00015608-08

NCGC00016828-01

NCGC00024818-01

NCGC00024818-02

NCGC00024818-03

NCGC00024818-04

NCGC00024818-05

nchembio.559-comp8

nchembio.79-comp7

NINDS_000215

Nu-loperamide

Nu-Loperamide

Oprea1_109220

Pepto Diarrhea Control

PMS-Loperamide

Prestwick0_000144

Prestwick1_000144

Prestwick2_000144

Prestwick3_000144

R-18553

rho-Loperamide

Rho-Loperamide

SPBio_001816

SPBio_002187

Spectrum_000374

Spectrum2_001738

Spectrum3_001015

Spectrum4_001143

Spectrum5_001374

ST095179

Tocris-0840

UNII-6X9OC3H4II

Rifaximin

Approved, Investigational

Not Applicable

80621-81-4

6436173

Synonyms:

(2S,16Z,18E,20S,21S,22R,23R,24R,25S,26S,27S,28E)-5,6,21,23,25 Pentahydroxy-27-methoxy-2,4,11,16,20,22,24,26-octamethyl-2,7-(epoxypentadeca(1,11,13)trienimino)benzofuro(4,5-e)pyrido(1,2-a)benzimidazole-1,15(2H)-dione, 25-acetate

4-deoxy-4'-methylpyrido(1',2'-1,2)imidazo(5,4C)rifamycin

4-Deoxy-4'-methylpyrido(1',2'-1,2)imidazo(5,4C)rifamycin

4-Deoxy-4'-methylpyrido(1',2'-1,2)imidazo(5,4-c)rifamycin SV

80621-81-4

88747-56-2

AC-19112

alpha-0817185

Bio-0556

BRN 3584528

C43H51N3O11

CHEMBL1617

D02554

DB01220

Fatroximin

Flonorm

L 105

L 105 (Ansamacrolide antibiotic)

L 105SV

Lormyx

LS-178059

LS-64147

Lumenax

MLS000759430

Normix

Redactiv

RedActiv

Rifacol

Rifamixin

Rifamycin L 105

Rifamycin L 105SV

Rifaxidin

Rifaximin

Rifaximin (USAN/INN)

Rifaximin [USAN:INN]

Rifaximina

Rifaximina [Spanish]

Rifaximine

Rifaximine [French]

Rifaximinum

Rifaximinum [Latin]

Rifaximinun

Rifaxin

Ritacol

S1790_Selleck

SMR000466324

Spiraxin

UNII-L36O5T016N

Xifaxan

Xifaxan, Rifacol, Fatroximin, Rifaximin

Xifaxsan

Xifaxsan (TN)

Imidacloprid

Vet_approved

Not Applicable

105827-78-9

86418

Synonyms:

(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine

(e)-Imidacloprid

(Z)-Imidacloprid

1-((6-chloro-3-Pyridinyl)methyl)-N-nitro-2-imidazolidinimine

1-((6-chloro-3-Pyridyl)methyl)-N-nitro-2-imidazolidinimine

1-(2-chloro-5-Pyridylmethyl)-2-(nitroimino)imidazolidine

1-[(6-chloro-3-Pyridinyl)methyl]-4,5-dihydro-N-nitro-1H-imidazol-2-amine, 9ci

Admire

Advantage

Advantage flea adulticide

Bayer brand OF imidacloprid

Confidor

Confidor 200 SL

Confidor SL

Gaucho

IMD

Imidacloprid (old RN)

Merit

Merit (insecticide)

Premise 75

Provado

Antirheumatic Agents

Not Applicable

Insulin, Globin Zinc

Not Applicable

Hypoglycemic Agents

Not Applicable

insulin

Not Applicable

Interleukin 1 Receptor Antagonist Protein

Not Applicable

Narcotics

Sitagliptin Phosphate

Not Applicable

protease inhibitors

Not Applicable

Incretins

Not Applicable

Dipeptidyl-Peptidase IV Inhibitors

Not Applicable

HIV Protease Inhibitors

Not Applicable

Antidiarrheals

Not Applicable

Gastrointestinal Agents

Not Applicable

Anti-Infective Agents

Not Applicable

Nucleic Acid Synthesis Inhibitors

Not Applicable

Anti-Bacterial Agents

Not Applicable

Antibiotics, Antitubercular

Not Applicable

glucagon

Not Applicable

Glucagon-Like Peptide 1

Not Applicable

Interventional clinical trials:

(show all 30)

#	Name	Status	NCT ID	Phase	Drugs
1	Treatment of the Dumping Syndrome With Lanreotide Autogel®	Unknown status	NCT00543179	Phase 4	Somatuline (Lanreotide Autogel®)
2	Study to Allow Access to Pasireotide for Patients Benefiting From Pasireotide Treatment in a Novartis-sponsored Study.	Recruiting	NCT01794793	Phase 4	Pasireotide
3	Impact of the Techniques for Intrathoracic Esophagogastric Anastomosis on Outcome in Ivor-Lewis Oesophagectomy	Unknown status	NCT01242124	Phase 2, Phase 3
4	Comparison of Laparoscopic Pylorus Preserving Gastrectomy Versus Laparoscopic Distal Gastrectomy	Recruiting	NCT02595086	Phase 3
5	Randomized Controlled Trials Comparing Clinical Outcomes of 3D Versus 2D Laparoscopic Surgery for Gastric Cancer	Active, not recruiting	NCT02327481	Phase 3
6	SOMATULINE Autogel 90 mg IN DUMPING SYNDROME	Unknown status	NCT01923649	Phase 2	Lanreotide 90 mg slow release formulation;Placebo
7	Study to Assess Safety and Efficacy of sc Pasireotide in Patients With Dumping Syndrome	Completed	NCT01895296	Phase 2	Pasireotide;Placebo
8	Phase II Study Evaluating Efficacy, Safety and Pharmacokinetics of Pasireotide in Patients With Dumping Syndrome	Completed	NCT01637272	Phase 2	SOM230
9	Evaluation of Single Ascending Doses of Subcutaneous Exendin 9-39 in Patients With Post-Bariatric Hypoglycemia	Unknown status	NCT02996812	Phase 1	Exendin (9-39)
10	Banded Sleeve Gastrectomy Versus Banded Ring Gastric Bypass in Morbidly Obese Patients	Unknown status	NCT00873405	Not Applicable
11	A Study Comparing Billroth II With Roux-en-Y Reconstruction for Gastric Cancer	Unknown status	NCT01257711	Not Applicable
12	Postprandial Hypoglycemia in Patients After Bariatric Surgery With Empagliflozin and Anakinra - The Hypo-BEAR-Study	Completed	NCT03200782	Not Applicable	Empagliflozin;Anakinra
13	Idiopathic Reactive Hypoglycaemia and Treatment With Fructo-Oligosaccharide	Completed	NCT00802971	Not Applicable
14	Chronic Marginal Ulcers After Gastric Bypass	Completed	NCT01041079
15	Treatment of Diabetes After Gastric Bypass With Sitagliptin	Completed	NCT01512797	Not Applicable	Sitagliptin phosphate
16	Omega Loop Versus Roux-en-Y Gastric Bypass	Completed	NCT02139813	Not Applicable
17	Impact of an Educational Personalized Clinical Support Device Preventive and a Referent Nurse in Surgery for Obesity	Recruiting	NCT02891330	Not Applicable
18	Dumping Syndrome After Operation of Esophageal Atresia Type III	Recruiting	NCT02525705	Not Applicable
19	Comparisons Between Isoperistaltic and Antiperistaltic Gastrojejunostomy in Laparoscopic Distal Gastrectomy	Recruiting	NCT02837874	Not Applicable
20	Metabolic Consequences of Gastrointestinal Surgery	Recruiting	NCT02836353	Not Applicable	Somatostatin;Rifaximin
21	Neujia Anastomosis for Treatment of Obesity and Type II Diabetes	Recruiting	NCT03675074	Not Applicable
22	Single-anastomosis Duodeno Ileal Bypass (SADI) Versus Roux-en-Y Gastric Bypass	Recruiting	NCT03610256	Not Applicable
23	Routine Post-Operative Supplemental Nutrition	Active, not recruiting	NCT02297607	Not Applicable
24	Type 2 Diabetes After Sleeve Gastrectomy and Roux-en-Y Gastric Bypass: A Randomised Single Centre Study	Active, not recruiting	NCT01778738	Not Applicable
25	Laparoscopic Versus Open Gastrectomy for Gastric Cancer	Active, not recruiting	NCT02248519	Not Applicable
26	Gastrectomy, Eating Behaviour and GLP-1	Enrolling by invitation	NCT02971631	Not Applicable
27	Gastrointestinal Nutrient Transit and Enteroendocrine Function After Upper Gastrointestinal Surgery	Enrolling by invitation	NCT03734627		Octreotide Acetate;Saline Solution;Paracetamol;Sulfasalazine
28	Intestinal Metabolic Reprogramming as a Key Mechanism of Gastric Bypass in Humans	Enrolling by invitation	NCT02710370
29	Role and Mechanisms of Obesity Surgery - Physical Activity and Other Predictors of Hospital Stay, Recovery and Complications After Obesity Surgery	Suspended	NCT01998815
30	Assessment of Gastric Emptying Speed in Patients Who Experience Diarrhea Following a Trigger Meal	Withdrawn	NCT01114113	Not Applicable	pancelipase/placebo

Search NIH Clinical Center for Dumping Syndrome

Cochrane evidence based reviews: dumping syndrome

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Genetic Tests for Dumping Syndrome

Sources

Anatomical Context for Dumping Syndrome

MalaCards organs/tissues related to Dumping Syndrome:

⁴¹

Small Intestine, Testes, Lymph Node, Liver, Pituitary, Pancreas, Thyroid

Sources

Publications for Dumping Syndrome

Articles related to Dumping Syndrome:

(show top 50) (show all 892)

#	Title	Authors	Year
1	Safety and efficacy of pasireotide in dumping syndrome-results from a phase 2, multicentre study. ( 29696671 )	Tack J....Van Beek A.P.	2018
2	Post-Fundoplication Dumping Syndrome: A Frequent &quot;Rare&quot; Complication. ( 29379815 )	Kataria R....Schey R.	2018
3	Transient severe distributive shock due to early dumping syndrome: a case report. ( 30208930 )	Takeshita J...Shime N	2018
4	Applications of peptide hormone ligands for the treatment of dumping and short bowel syndrome. ( 30273889 )	Wauters L...Vanuytsel T	2018
5	The Effect of Dumping on Weight Loss in Conversion of Failed Restrictive Surgery: a Cross-Sectional Pilot Study. ( 28933032 )	Van Looveren R...Smet B	2018
6	Assessing the risk of alcohol-induced dose dumping from sustained-release oral dosage forms: in vitro-in silico approach. ( 29043886 )	Cviji? S...Paroj?i? J	2018
7	Improving the monitoring of a dumping site in a dynamic environment. Example of the Octeville site (Bay of Seine, English Channel). ( 29055561 )	M?ar Y...Dauvin JC	2018
8	Deep sea habitats in the chemical warfare dumping areas of the Baltic Sea. ( 29111251 )	Czub M...Be?dowski J	2018
9	Identifying areas under potential risk of illegal construction and demolition waste dumping using GIS tools. ( 29402616 )	Seror N...Portnov BA	2018
10	Effects of open dumping of MSW on metal contamination of soil, plants, and earthworms in Ranchi, Jharkhand, India. ( 29442190 )	Singh M...Kumar RN	2018
11	Predictors of illegal dumping at charitable collection points. ( 29453014 )	Wright B...Tull F	2018
12	On the dumping ground genus Scotaena Klug, 1810 (Hymenoptera: Tiphiidae: Thynninae): Phylogeny, taxonomy and geographic distribution. ( 29690290 )	Carnimeo FH...Noll FB	2018
13	Impact of dredged-material disposal on soft-bottom communities in a recurrent marine dumping area near to Guadalquivir estuary, Spain. ( 29773315 )	Don?zar-Aramend?a I...Garc?a-G?mez JC	2018
14	Long-term self-reported symptom prevalence of early and late dumping in a patient population after sleeve gastrectomy, primary, and revisional gastric bypass surgery. ( 29858129 )	Emous M...van Beek AP	2018
15	Europe's biggest research fund cracks down on 'ethics dumping'. ( 29970912 )	Nordling L	2018
16	946 nm Nd:YAG laser with cavity dumping. ( 30004529 )	Kornev AF...Kovyarov AS	2018
17	Mercury contamination in the sludge of drinking water treatment plants dumping into a reservoir in Rio de Janeiro, Brazil. ( 30099710 )	Wasserman JC...de Paiva Lima E	2018
18	Phytoremediation of waste dumping site soil and landfill leachate by using cattail (Typha latifolia). ( 30198835 )	Xu Q...Yuan Q	2018
19	Dumping to the abyss: single-use marine litter invading bathyal plains of the Sardinian margin (Tyrrhenian Sea). ( 30301106 )	Cau A...Follesa MC	2018
20	Patient Dumping Is Still a Problem. ( 30358587 )	Kritz F	2018
21	Prevalence and pathophysiology of early dumping in patients after primary Roux-en-Y gastric bypass during a mixed-meal tolerance test. ( 30446401 )	Wijma RB...van Beek AP	2018
22	Prevalence and pathophysiology of early dumping in patients after primary Roux-en-Y gastric bypass during a mixed-meal tolerance test. ( 30503167 )	Rogers AM	2018
23	Insight into occurrence, profile and spatial distribution of organochlorine pesticides in soils of solid waste dumping sites of Pakistan: Influence of soil properties and implications for environmental fate. ( 30529619 )	Sultan M...Malik RN	2018
24	Severe Dumping Syndrome in a 6-year-old Girl with Congenital Microgastria Treated by Hunt-Lawrence Pouch. ( 28361011 )	Filisetti C....Riccipetitoni G.	2017
25	Effectiveness of sitagliptin in a patient with late dumping syndrome after total gastrectomy. ( 29208515 )	Kurihara K....Hosoi M.	2017
26	A case report: Liraglutide as a novel treatment option in late dumping syndrome. ( 28328816 )	Chiappetta S....Stier C.	2017
27	Late Dumping Syndrome in a 17-Year-Old Female With Charge Syndrome. ( 29205658 )	Morgan A....Blake K.	2017
28	Pregnancy and Dumping Syndrome post-bariatric surgery: a case report. ( 28473681 )	Edawati D.E....Harris N.S.	2017
29	Dumping syndrome after esophageal, gastric or bariatric surgery: pathophysiology, diagnosis, and management. ( 27749997 )	Van Beek A.P....Tack J.	2017
30	The short- to mid-term symptom prevalence of dumping syndrome after primary gastric-bypass surgery and its impact on health-related quality of life. ( 28624531 )	Emous M....Van Beek A.P.	2017
31	Incretin Kinetics Before and After Miglitol in Japanese Patients With Late Dumping Syndrome. ( 28912925 )		2017
32	Pasireotide and octreotide in the treatment of severe late dumping syndrome. ( 29026555 )		2017
33	Experience with FreeStyle Libre Flash glucose monitoring system in management of refractory dumping syndrome in pregnancy shortly after bariatric surgery. ( 29302329 )		2017
34	Dumping Syndrome ( 29261889 )		2017
35	Dumping the information bucket: A qualitative study of clinicians caring for patients with early stage non-small cell lung cancer. ( 28034611 )	Golden SE...Early Stage Lung Cancer Comparative Effectiveness Research Consortium	2017
36	High peak power cavity dumping semiconductor lasers. ( 28059191 )	Myers J...Bedford R	2017
37	Traffic accident or dumping? - Striking results of a traffic accident reconstruction. ( 28081791 )	Nerger E...Ondruschka B	2017
38	Individual Physician Penalties Resulting From Violation of Emergency Medical Treatment and Labor Act: A Review of Office of the Inspector General Patient Dumping Settlements, 2002-2015. ( 28109011 )	Terp S...Menchine M	2017
39	Before-After analysis of the trophic network of an experimental dumping site in the eastern part of the Bay of Seine (English Channel). ( 28233526 )	Pezy JP...Dauvin JC	2017
40	Can soda ash dumping grounds provide replacement habitats for digger wasps (Hymenoptera, Apoidea, Spheciformes)? ( 28423033 )	Twerd L...Olszewski P	2017
41	Dumping symptoms is triggered by fat as well as carbohydrates in patients operated with Roux-en-Y gastric bypass. ( 28433465 )	Laurenius A...Olbers T	2017
42	Iron-dumping ocean experiment sparks controversy. ( 28541342 )	Tollefson J	2017
43	Ecological risk assessment of an open dumping site at Mehmood Booti Lahore, Pakistan. ( 28616741 )	Alam A...Mahmood A	2017
44	Variations in the concentrations of heavy metals through enforcement of a rest-year system and dredged sediment capping at the Yellow Sea-Byung dumping site, Korea. ( 28733040 )	Chung CS...Kim CJ	2017
45	Offal dumping sites influence the relative abundance and roosting site selection of Black Kites (Milvus migrans govinda) in urban landscape: a study from Kolkata metropolis, India. ( 29238878 )	Mazumdar S...Saha GK	2017
46	Risk of Dumping Syndrome after Sleeve Gastrectomy and Roux-en-Y Gastric Bypass: Early Results of a Multicentre Prospective Study. ( 27242898 )	Ramadan M....Nocca D.	2016
47	Dumping syndrome after esophagectomy: a systematic review of the literature. ( 27859950 )	Boshier P.R....Hanna G.B.	2016
48	Specific Features of Dumping Syndrome after Various Types of Gastrectomy as Assessed by a Newly Developed Integrated Questionnaire, the PGSAS-45. ( 26682541 )	Tanizawa Y....Nakada K.	2016
49	Durable Flap-Valve Mitigation of Duodenogastric Reflux, A Remnant GastritisA and Dumping Syndrome Following Billroth I Reconstruction. ( 26666548 )	Hoya Y....Yanaga K.	2016
50	PATHOPHYSIOLOGY, DIAGNOSIS AND TREATMENTOF DUMPING SYNDROME AND ITS RELATION TO BARIATRIC SURGERY. ( 27683791 )		2016

Sources

Genes for Dumping Syndrome

Genes related to Dumping Syndrome (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	SST	Somatostatin	Protein Coding	31.65	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵ GeneCards inferred via : Publications (show sections)	8103615 1978748 19724252 (more) 8359570 8317033 19264574 7933883
2	NTS	Neurotensin	Protein Coding	29.75	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵ GeneCards inferred via : Publications (show sections)	9403815
3	PYY	Peptide YY	Protein Coding	26.98	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵ GeneCards inferred via : Publications (show sections)	1415124
4	GCG	Glucagon	Protein Coding	25.15	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵ GeneCards inferred via : Publications (show sections)	16416173 9200302 11575444
5	INS	Insulin	Protein Coding	23.23	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
6	GIP	Gastric Inhibitory Polypeptide	Protein Coding	22.68	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
7	SCT	Secretin	Protein Coding	20.68	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)

Sources

Variations for Dumping Syndrome

Sources

Expression for Dumping Syndrome

Search GEO for disease gene expression data for Dumping Syndrome.

Sources

Pathways for Dumping Syndrome

Pathways related to Dumping Syndrome according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Signaling by GPCR ⁶⁶ Show member pathways GPCR downstream signaling ⁶⁶ Signal Transduction ⁶⁶	13.4	GCG GIP INS NTS PYY SCT
2	Peptide ligand-binding receptors ⁶⁶ Show member pathways Class A/1 (Rhodopsin-like receptors) ⁶⁶ Defective AVP causes neurohypophyseal diabetes insipidus (NDI) ⁶⁶ Formyl peptide receptors bind formyl peptides and many other ligands ⁶⁶ G alpha (i) signalling events ⁶⁶ GPCR ligand binding ⁶⁶ GPCRs, Class A Rhodopsin-like ¹ Neuroactive ligand-receptor interaction ³⁷ Orexin and neuropeptides FF and QRFP bind to their respective receptors ⁶⁶ Peptide GPCRs ¹ Tachykinin receptors bind tachykinins ⁶⁶ Vasopressin-like receptors ⁶⁶	12.37	GCG GIP NTS PYY SCT SST
3	Aldosterone synthesis and secretion ³⁷ Show member pathways Adrenergic signaling in cardiomyocytes ³⁷ Ca2+ activated K+ channels ⁶⁶ Cortisol synthesis and secretion ³⁷ Insulin secretion ³⁷ Thyroid hormone synthesis ³⁷	12.28	GCG GIP INS
4	Presynaptic function of Kainate receptors ⁶⁶ Show member pathways Activation of Ca-permeable Kainate Receptor ⁶⁶ Activation of Kainate Receptors upon glutamate binding ⁶⁶ Activation of Na-permeable Kainate Receptors ⁶⁶ Calcitonin-like ligand receptors ⁶⁶ Class B/2 (Secretin family receptors) ⁶⁶ G beta-gamma signalling through PLC beta ⁶⁶ Glucagon-type ligand receptors ⁶⁶ G-Protein Signaling through Tubby Protein ⁶⁴ Ionotropic activity of Kainate Receptors ⁶⁶	11.9	GCG GIP SCT
5	Peptide hormone metabolism ⁶⁶ Show member pathways Glycoprotein hormones ⁶⁶ Insulin processing ⁶⁶ Metabolism of Angiotensinogen to Angiotensins ⁶⁶ Peptide hormone biosynthesis ⁶⁶ Synthesis, secretion, and deacylation of Ghrelin ⁶⁶	11.69	GCG GIP INS
6	G alpha (s) signalling events ⁶⁶	11.3	GCG GIP SCT
7	Incretin synthesis, secretion, and inactivation ⁶⁶ Show member pathways Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) ⁶⁶ Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) ⁶⁶	11.15	GCG GIP
8	FOXA1 transcription factor network ¹ Show member pathways FOXA transcription factor networks ¹	11.03	GCG INS

Sources

GO Terms for Dumping Syndrome

Cellular components related to Dumping Syndrome according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	endoplasmic reticulum lumen	GO:0005788	9.43	GCG GIP INS
2	extracellular space	GO:0005615	9.43	GCG GIP INS PYY SCT SST
3	secretory granule lumen	GO:0034774	9.33	GCG GIP INS
4	transport vesicle	GO:0030133	9.32	INS NTS
5	extracellular region	GO:0005576	9.17	GCG GIP INS NTS PYY SCT

Biological processes related to Dumping Syndrome according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	G protein-coupled receptor signaling pathway	GO:0007186	9.5	GCG GIP INS NTS PYY SCT
2	regulation of insulin secretion	GO:0050796	9.4	GCG GIP
3	response to amino acid	GO:0043200	9.37	GIP SST
4	feeding behavior	GO:0007631	9.32	GCG PYY
5	positive regulation of cAMP-mediated signaling	GO:0043950	9.26	GIP SCT
6	regulation of signaling receptor activity	GO:0010469	9.17	GCG GIP INS NTS PYY SCT
7	response to acidic pH	GO:0010447	9.16	GIP SST

Molecular functions related to Dumping Syndrome according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	G protein-coupled receptor binding	GO:0001664	9.16	PYY SCT
2	hormone activity	GO:0005179	9.1	GCG GIP INS PYY SCT SST
3	neuropeptide hormone activity	GO:0005184	8.96	NTS PYY

Sources

Sources for Dumping Syndrome

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ ExPASy

¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia