MCID: DMP001
MIFTS: 44

Dumping Syndrome

Categories: Gastrointestinal diseases

Aliases & Classifications for Dumping Syndrome

MalaCards integrated aliases for Dumping Syndrome:

Name: Dumping Syndrome 12 55 44 15 17 72
Dumping 55 72
Postgastrectomy Syndromes 72
Dumping Syndrome 12
Jejunal Syndrome 12

Classifications:



External Ids:

Disease Ontology 12 DOID:14495
MeSH 44 D004377
NCIt 50 C2994
SNOMED-CT 68 80193009
ICD10 33 K91.1
UMLS 72 C0013288 C0032763 C0221542

Summaries for Dumping Syndrome

MalaCards based summary : Dumping Syndrome, also known as dumping, is related to hyperinsulinemic hypoglycemia and gastroesophageal reflux, and has symptoms including constipation, pain, postoperative and postoperative nausea and vomiting. An important gene associated with Dumping Syndrome is SST (Somatostatin), and among its related pathways/superpathways are Signaling by GPCR and Aldosterone synthesis and secretion. The drugs lanreotide and Pasireotide have been mentioned in the context of this disorder. Affiliated tissues include small intestine, testes and brain.

Wikipedia : 75 Dumping syndrome occurs when food, especially sugar, moves too quickly from the stomach to the... more...

Related Diseases for Dumping Syndrome

Diseases related to Dumping Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 111)
# Related Disease Score Top Affiliating Genes
1 hyperinsulinemic hypoglycemia 30.5 SST INS
2 gastroesophageal reflux 30.3 PYY NTS GCG
3 duodenal ulcer 30.3 SST SCT INS
4 hyperinsulinism 30.0 SST INS
5 diabetes mellitus, insulin-dependent 29.5 SST INS GCG
6 constipation 29.4 SST PYY NTS
7 glucose intolerance 29.3 INS GCG
8 insulinoma 29.2 SST SCT INS GCG
9 hyperglycemia 29.1 SST INS GIP GCG
10 duodenogastric reflux 28.9 SST SCT PYY NTS
11 short bowel syndrome 28.9 SST PYY NTS GCG
12 gastrointestinal system disease 28.0 SST SCT PYY INS GCG
13 diabetes mellitus, noninsulin-dependent 27.6 SST PYY INS GIP GCG
14 hypoglycemia 10.8
15 peptic ulcer disease 10.6
16 diarrhea 10.5
17 type 1 diabetes mellitus 15 10.3 INS GCG
18 hyperinsulinemic hypoglycemia, familial, 7 10.3 INS GCG
19 maturity-onset diabetes of the young, type 9 10.3 INS GCG
20 leptin deficiency or dysfunction 10.3
21 hirata disease 10.3 INS GCG
22 gastrointestinal ulceration, recurrent, with dysfunctional platelets 10.3
23 acute insulin response 10.3 INS GCG
24 pancreatoblastoma 10.3 SST NTS
25 prediabetes syndrome 10.2 INS GCG
26 space motion sickness 10.2 SCT NTS
27 duodenal somatostatinoma 10.2 SST INS
28 somatostatinoma 10.2 SST INS
29 pancreatic endocrine carcinoma 10.2 SST INS
30 afferent loop syndrome 10.2
31 hyperpituitarism 10.2 SST INS
32 hyperproinsulinemia 10.2 SCT INS
33 functional gastric disease 10.1 SST INS
34 glucagonoma 10.1 SST SCT
35 islet cell tumor 10.1 SST INS
36 iron metabolism disease 10.1
37 47,xyy 10.1
38 dysphagia 10.1
39 angiodysplasia 10.1 SST SCT
40 pituitary-dependent cushing's disease 10.1 SST INS
41 maturity-onset diabetes of the young, type 7 10.1 SCT INS
42 duodenal gastrinoma 10.1 SST SCT
43 endocrine organ benign neoplasm 10.1 SST INS
44 steatorrhea 10.1 SST SCT
45 thyroid gland disease 10.1 SST INS
46 pituitary gland disease 10.1 SST INS
47 cell type benign neoplasm 10.0 SST INS
48 ocular motor apraxia 10.0
49 arts syndrome 10.0
50 body mass index quantitative trait locus 1 10.0

Graphical network of the top 20 diseases related to Dumping Syndrome:



Diseases related to Dumping Syndrome

Symptoms & Phenotypes for Dumping Syndrome

UMLS symptoms related to Dumping Syndrome:


constipation, pain, postoperative, postoperative nausea and vomiting, vomiting following gastrointestinal surgery

Drugs & Therapeutics for Dumping Syndrome

Drugs for Dumping Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 74)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
lanreotide Approved Phase 4 108736-35-2
2
Pasireotide Approved Phase 4 396091-73-9 9941444
3
Empagliflozin Approved Phase 4 864070-44-0
4
Dopamine Approved Phase 4 51-61-6, 62-31-7 681
5
Cabergoline Approved Phase 4 81409-90-7 54746
6
Orlistat Approved, Investigational Phase 4 96829-58-2 3034010
7
Linagliptin Approved Phase 4 668270-12-0 10096344
8
Liraglutide Approved Phase 4 204656-20-2 44147092
9
Canagliflozin Approved Phase 4 842133-18-0
10
Lactitol Investigational Phase 4 585-86-4, 585-88-6 493591
11 Angiopeptin Phase 4
12 Hormones Phase 4
13 Hormone Antagonists Phase 4
14 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4
15 Incretins Phase 4
16 Sodium-Glucose Transporter 2 Inhibitors Phase 4
17 Hypoglycemic Agents Phase 4
18 Neurotransmitter Agents Phase 4
19 Dopamine Agents Phase 4
20 Antiparkinson Agents Phase 4
21 Dopamine agonists Phase 4
22 Anti-Obesity Agents Phase 4
23 HIV Protease Inhibitors Phase 4
24 Sitagliptin Phosphate Phase 4
25 Lipid Regulating Agents Phase 4
26
protease inhibitors Phase 4
27 Dipeptidyl-Peptidase IV Inhibitors Phase 4
28
Exenatide Approved, Investigational Phase 1 141758-74-9 15991534
29
Guaifenesin Approved, Investigational, Vet_approved Phase 1 93-14-1 3516
30
Hydrocodone Approved, Illicit, Investigational Phase 1 125-29-1 5284569
31
Glucagon Approved Phase 1 16941-32-5
32 Analgesics Phase 1
33 Peripheral Nervous System Agents Phase 1
34 Narcotics Phase 1
35 Chlorpheniramine, phenylpropanolamine drug combination Phase 1
36 Respiratory System Agents Phase 1
37 Central Nervous System Depressants Phase 1
38 Analgesics, Opioid Phase 1
39 Antitussive Agents Phase 1
40
Glimepiride Approved 93479-97-1 3476
41
Metformin Approved 657-24-9 4091 14219
42
Loperamide Approved 53179-11-6 3955
43
Somatostatin Approved, Investigational 38916-34-6, 51110-01-1 53481605
44
Octreotide Approved, Investigational 83150-76-9 383414 6400441
45
Acetaminophen Approved 103-90-2 1983
46
Sulfasalazine Approved 599-79-1 5359476 5353980
47
Methylene blue Approved, Investigational 61-73-4
48
Rifaximin Approved, Investigational 80621-81-4 46783403 6436173
49 Trichostatin A
50 Vitamins

Interventional clinical trials:

(show all 50)
# Name Status NCT ID Phase Drugs
1 Treatment of the Dumping Syndrome With Lanreotide Autogel® Unknown status NCT00543179 Phase 4 Somatuline (Lanreotide Autogel®)
2 An Open Label, Multi-center Pasireotide Roll-over Protocol for Patients Who Have Completed a Previous Novartis-sponsored Pasireotide Study and Are Judged by the Investigator to Benefit From Continued Pasireotide Treatment Recruiting NCT01794793 Phase 4 Pasireotide;Cabergoline;Pasireotide
3 Roux-en-Y Gastric Bypass for BMI 27-32 Type 2 Diabetes vs Best Medical Treatment Recruiting NCT02041234 Phase 4 Incretin analogues;Xenical;SGLT2 inhibitors;DPP-4 Inhibitors
4 Multicenter Randomized Controlled Trial Comparing Laparoscopic Pylorus Preserving Gastrectomy Versus Laparoscopic Distal Gastrectomy for the Middle Third Early Gastric Cancer (KLASS-04) Recruiting NCT02595086 Phase 3
5 Dasiglucagon in the Treatment of Postprandial Hypoglycaemia After Roux-en-Y Gastric Bypass Not yet recruiting NCT03984370 Phase 3 ZP4207
6 Hyperbaric Oxygenation (HBO) in Chronic Diabetic Leg Ulcer. Not yet recruiting NCT02042339 Phase 3 Hyperbaric oxygen
7 SOMATULINE Autogel 90 mg IN DUMPING SYNDROME Unknown status NCT01923649 Phase 2 Lanreotide 90 mg slow release formulation;Placebo
8 A Multi-center, Intra-patient Dose Escalation Phase II Study to Evaluate the Preliminary Efficacy, Safety and Pharmacokinetics of Pasireotide (SOM230) Subcutaneous (s.c.) Followed by Pasireotide LAR in Patients With Dumping Syndrome Completed NCT01637272 Phase 2 SOM230
9 Exploratory Randomized, Placebo-controlled Study to Assess Safety and Efficacy of sc Pasireotide in Patients With Dumping Syndrome Completed NCT01895296 Phase 2 Pasireotide;Placebo
10 A Pilot Phase II Study of Hyperbaric Oxygen for Persistent Post-concussive Symptoms After Mild Traumatic Brain Injury (HOPPS) Completed NCT01306968 Phase 2 hyperbaric oxygen
11 Subcutaneous Injection of Exendin (9-39) in Subjects With Hyperinsulinemic Hypoglycemia Post-Bariatric Surgery Unknown status NCT02996812 Phase 1 Exendin (9-39)
12 Visualizing Beta Cells in Patients With Hyperinsulinemic Hypoglycemia After Bariatric Surgery Unknown status NCT03182192 Phase 1
13 A Phase I, Double-Blind, Placebo-Controlled, Randomized, 3-Period, Safety and Pharmacokinetic Study of 13C-uracil in a Semi-solid Meal at Single Oral Doses of 50, 100, and 200 mg in Healthy Volunteers Completed NCT01074710 Phase 1 [2-13C] uracil;[2-13C] uracil, placebo
14 A Randomized, Double-Blind, Placebo-Controlled, Crossover Study to Assess the Abuse Potential of the Hydrocodone Bitartrate Extended-Release Tablet in Healthy, Nondependent, Recreational Opioid Users Completed NCT01596673 Phase 1 45-mg hydrocodone bitartrate extended-release tablet (crushed or intact);Placebo
15 Treatment Plan for an Individual Patient With Pasireotide for Hyperinsulinemic Hypoglycemia Recruiting NCT03103009 Phase 1 Pasireotide
16 Gastric Emptying: in Vivo Studies in Healthy Volunteers (Using Scrambled Egg and Porridge) to Determine Reliable Normal Ranges Unknown status NCT02994472
17 A Prospective Randomised Study Comparing Billroth II With Roux-en-Y Reconstruction After Radical Distal Subtotal Gastrectomy for Gastric Cancer Unknown status NCT01257711
18 Incidence of Medical and Nutritional Complications After Bariatric Surgery, Especially Focusing on Assessment and Treatment of Severe Hypoglycemia Unknown status NCT01865760 Octreotide;Synthetic Exendin 9-39
19 Gastric Artery Embolization Trial for Lessening Appetite Nonsurgically (GET LEAN) Unknown status NCT02248688
20 Banded Sleeve Gastrectomy Versus Banded Ring Gastric Bypass in Morbidly Obese Patients: a Prospective Controlled Trial. Unknown status NCT00873405
21 Prevalence of Medical and Nutritional Complications After Bariatric Surgery (Gastric Bypass) Based on a Clinical Trial Unknown status NCT01930838
22 Frequency of Occurrence of Dumping Syndrome After Operation of Esophageal Atresia Type III Completed NCT02525705
23 Postprandial Hypoglycemia in Patients After Bariatric Surgery With Empagliflozin and Anakinra - The Hypo-BEAR-Study Completed NCT03200782 Empagliflozin;Anakinra
24 Oral Glucosestimulation After Gastric Bypass Surgery Completed NCT01851616
25 Prevalence of Idiopathic Reactive Hypoglycaemia and Impact of Fructo-Oligosaccharide Supplementation on Blood Glucose Variability Completed NCT00802971
26 Postoperative Dietary Counseling After Bariatric Surgery Completed NCT00125073
27 Role of Glucagon-Like Peptide-1 in Postprandial Hypoglycemia After Nissen Fundoplication: Studies With the GLP-1 Receptor Antagonist Exendin-(9-39) Completed NCT01162499 Exendin-(9-39)
28 Meal Stimulating After Roux-en Y Gastric Bypass Completed NCT00915980
29 Prevalence of Medical and Nutritional Complications After Bariatric Surgery (Gastric Bypass) Based on a Questionnaire Survey Completed NCT01930851
30 The Effect of Food on the Pharmacokinetics of Metformin Given Either as Metformin Hydrochloride SR 1000mg Tablet or as a Fixed Dose Combination of Metformin Hydrochloride SR 1000mg/Glimepiride 2mg Tablet in Healthy Indian Volunteers. Completed NCT01561976 Metformin hydrochloride prolonged release;metformin hydrochloride prolonged release;Metformin hydrochloride sustained release/Glimepiride
31 The Effect of Fat Supplementation on the Appearance of Symptoms Associated With Dumping Syndrome in Patients Undergone Bariatric Surgery Recruiting NCT04028193
32 Assessing the Impact of an Educational Personalized Clinical Support Device Preventive and a Referent Nurse in Surgery for Obesity With the Risk of Occurrence of Dumping Syndrome After Gastric Bypass. Recruiting NCT02891330
33 Incidence of Dumping Syndrome After Laparoscopic Vagus Nerve-preserving Distal Gastrectomy for Early Gastric Cancer Recruiting NCT03880747
34 Comparisons Between Isoperistaltic and Antiperistaltic Gastrojejunostomy in Laparoscopic Distal Gastrectomy, Randomized Prospective Pilot Study Recruiting NCT02837874
35 Functional Outcome Following Ivor-Lewis Oesophagectomy Recruiting NCT03658837
36 Cohorte Obésité Bichat LOuis Mourier Recruiting NCT03538210
37 European Dumping Study: Validation of a Diagnostic Tool for Postprandial Hypoglycaemia in Patients After Roux en Y Gastric Bypass Surgery Recruiting NCT03406312
38 Mayo Clinic Conduit Report Card Questionnaires Recruiting NCT02530983
39 A 90 Day, Phase 4, Open Labeled Exploratory Study of RELiZORB to Evaluate Safety, Tolerability, and Nutrient Absorption in Children With Short Bowel Syndrome Who Are Dependent on Parenteral Nutrition Recruiting NCT03530852
40 Mandibular Reconstruction Using Tissue Regeneration With Axially Vascularised Bone Substitutes Recruiting NCT04001842
41 ENSURE: European iNvestigation of SUrveillance After Resection for Esophageal Cancer Active, not recruiting NCT03461341
42 An Intervention Model for the Prevention of Infertility in Healthy Young Men Living in Highly Polluted Areas Active, not recruiting NCT04012385
43 The Effect of Glucagon Like Peptide-1 (GLP-1) on Glycaemic Profile and Eating Behaviour Following Gastrectomy Enrolling by invitation NCT02971631
44 Gastrointestinal Nutrient Transit and Enteroendocrine Function After Upper Gastrointestinal Surgery Enrolling by invitation NCT03734627 Octreotide Acetate;Saline Solution;Paracetamol;Sulfasalazine
45 Gastric Cancer Sentinel Lymph Node Sampling: Refining Patient Selection for Organ Sparing Resection of Early Gastric Cancer in a North American Context Enrolling by invitation NCT03049345 Radioactive Tracers;Methylene Blue 20 MG/ML
46 Applying Nutrient Drink Test in Understanding Pathophysiology of Cyclic Vomiting Syndrome Enrolling by invitation NCT03470181
47 Role and Mechanisms of Obesity Surgery - Physical Activity and Other Predictors of Hospital Stay, Recovery and Complications After Obesity Surgery Suspended NCT01998815
48 The Metabolic Consequences of Gastrointestinal Surgery Terminated NCT02836353 Somatostatin;Rifaximin
49 Evaluation of an Intervention (Consisting of an Electronic Reminder Device, Pillboxes, and Monthly Telephone Calls) on Adherence to Highly Active Antiretroviral Therapy (HAART) in HIV Infected Adults Terminated NCT00203853
50 Pilot Study: Assessment of Gastric and Intestinal Motility Following a Trigger Meal in Patients With Post Prandial Diarrhea Withdrawn NCT01114113 pancelipase/placebo

Search NIH Clinical Center for Dumping Syndrome

Cochrane evidence based reviews: dumping syndrome

Genetic Tests for Dumping Syndrome

Anatomical Context for Dumping Syndrome

MalaCards organs/tissues related to Dumping Syndrome:

41
Small Intestine, Testes, Brain, Colon, Liver, Lung, Lymph Node

Publications for Dumping Syndrome

Articles related to Dumping Syndrome:

(show top 50) (show all 3519)
# Title Authors PMID Year
1
Pathophysiology, diagnosis and management of postoperative dumping syndrome. 9 38
19724252 2009
2
Efficacy of the long-acting repeatable formulation of the somatostatin analogue octreotide in postoperative dumping. 9 38
19264574 2009
3
A possible role of GLP-1 in the pathophysiology of early dumping syndrome. 9 38
16416173 2005
4
Postprandial GLP-1, norepinephrine, and reactive hypoglycemia in dumping syndrome. 9 38
11575444 2001
5
Gastrointestinal hormone in dumping syndrome and reflux esophagitis after gastric surgery. 9 38
9403815 1997
6
The dumping syndrome. Current insights into pathophysiology, diagnosis and treatment. 9 38
9200302 1997
7
[Neurohumoral regulation of gastric secretion in postvagotomy syndromes]. 9 38
7933883 1994
8
[Postgastrectomy dumping treated with octreotide (Sandostatin)]. 9 38
8317033 1993
9
The effect of somatostatin in dumping syndrome after gastric surgery. 9 38
8103615 1993
10
Atrial natriuretic peptide in dumping syndrome. 9 38
8513987 1993
11
Potential indications for octreotide in gastroenterology: summary of workshop. 9 38
8359570 1993
12
Dumping syndrome and the regulation of peptide YY with verapamil. 9 38
1415124 1992
13
Decreased activity of atrial natriuretic peptide in dumping syndrome after gastric surgery. 9 38
1830840 1991
14
[The effect of somatostatin in dumping syndrome]. 9 38
1978748 1990
15
[Atrial natriuretic peptide in dumping syndrome]. 9 38
2146582 1990
16
Giving advice to callers with mental illness: adaptation among telenurses at Swedish Healthcare Direct. 38
31242817 2019
17
Does pregnancy interval after laparoscopic sleeve gastrectomy affect maternal and perinatal outcomes? 38
29712482 2019
18
Healthcare waste management in Asian developing countries: A mini review. 38
31266407 2019
19
Environmental, health, wellbeing, social and equity effects of urban green space interventions: A meta-narrative evidence synthesis. 38
31228780 2019
20
Environmental and economic feasibility of an integrated community composting plant and organic farm in Malaysia. 38
31153031 2019
21
[Long-term management after bariatric surgery]. 38
31436062 2019
22
The role of solid waste composting in mitigating climate change in Jordan. 38
31218931 2019
23
Silk Fibroin as a Novel Alcohol-Resistant Excipient for Sustained-Release Tablet Formulation. 38
31399868 2019
24
Quorum sensing inhibition as a promising method to control biofilm growth in metalworking fluids. 38
31020467 2019
25
Review on Indian Municipal Solid Waste Management practices for reduction of environmental impacts to achieve sustainable development goals. 38
31319199 2019
26
Saudi Arabia-China-Pakistan Economic Corridor: intergovernmental green initiatives. 38
31267397 2019
27
Using GIS and optimization to manage construction and demolition waste: The case of abandoned quarries in Lebanon. 38
31351599 2019
28
Characterizing the paper industry sludge for environmentally-safe disposal. 38
31351628 2019
29
Distribution and health risk assessment of arsenic and selected heavy metals in Groundwater of Chandigarh, India. 38
31048111 2019
30
Engineering a bioluminescent bioreporter from an environmentally sourced mercury-resistant Enterobacter cloacae strain for the detection of bioavailable mercury. 38
31336395 2019
31
A chronic toxicity study of diphenylarsinic acid in the drinking water of C57BL/6J mice for 52 weeks. 38
31404369 2019
32
Gastroparesis and Dumping Syndrome: Current Concepts and Management. 38
31362413 2019
33
The effect of ventricular volume increase in the amplitude of intracranial pressure. 38
30931613 2019
34
Diazoxide for the Treatment of Hypoglycemia Resulting From Dumping Syndrome in a Child. 38
31286099 2019
35
Gastrostomy Placement and Management in Children: A Single-Center Experience. 38
31295800 2019
36
Pregnancy after 24 Postoperative Months of Roux-En-Y Gastric Bypass Presents Risk of Pregnancy Complications Similar to Pregnancy within the First Postoperative Year. 38
31288227 2019
37
Sea-dumped ammunition as a possible source of mercury to the Baltic Sea sediments. 38
31005838 2019
38
A School of Nursing's Response to Hurricane Harvey. 38
31335491 2019
39
Crohn's Disease of the Esophagus, Duodenum, and Stomach. 38
31275069 2019
40
A Real-World, Insurance-Based Algorithm Using the Two-Fold Running Suture Technique for Transoral Outlet Reduction for Weight Regain and Dumping Syndrome After Roux-En-Y Gastric Bypass. 38
30937874 2019
41
Endoscopic Gastrojejunal Revision (Transoral Outlet Reduction) for Persistent Hypoglycemia After Gastric Bypass. 38
31338736 2019
42
Comparison of the dietary intake amongst women in the late postoperative period after Roux-en-Y gastric bypass with the bariatric food pyramidof dietary intake with reference values among women in late postoperative of y-en-roux gastric bypass. 38
30985187 2019
43
Slowed gastric emptying and improved oral glucose tolerance produced by a nanomolar-potency inhibitor of calcium-activated chloride channel TMEM16A. 38
31299174 2019
44
Environmental Impact of Heavy Metals from Poultry Waste Discharged into the Olosuru Stream, Ikire, Southwestern Nigeria. 38
31259083 2019
45
The Hyperbaric Protective Tube: A housing for a left ventricular assist device (LVAD) in a multiplace hyperbaric chamber. 38
31177520 2019
46
Vermicomposting process for treating animal slurry in Latin American rural areas. 38
30950327 2019
47
Extreme spatial variation of Sr, Nd and Pb isotopic signatures and 48 element mass fractions in surface sediment of the Elbe River Estuary - Suitable tracers for processes in dynamic environments? 38
30856563 2019
48
Trends of electronic waste pollution and its impact on the global environment and ecosystem. 38
31025281 2019
49
Organochlorine pesticides air monitoring near a historical lindane production site in Spain. 38
31018415 2019
50
Drivers of legal and illegal solid waste disposal in the Global South - The case of households in Yaoundé (Cameroon). 38
30953985 2019

Variations for Dumping Syndrome

Expression for Dumping Syndrome

Search GEO for disease gene expression data for Dumping Syndrome.

Pathways for Dumping Syndrome

Pathways related to Dumping Syndrome according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.4 SST SCT PYY NTS INS GIP
2
Show member pathways
12.38 INS GIP GCG
3
Show member pathways
12.38 SST SCT PYY NTS GIP GCG
4
Show member pathways
11.9 SCT GIP GCG
5
Show member pathways
11.69 INS GIP GCG
6 11.3 SCT GIP GCG
7
Show member pathways
11.15 GIP GCG
8
Show member pathways
11.03 INS GCG

GO Terms for Dumping Syndrome

Cellular components related to Dumping Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 endoplasmic reticulum lumen GO:0005788 9.43 INS GIP GCG
2 extracellular space GO:0005615 9.43 SST SCT PYY INS GIP GCG
3 secretory granule lumen GO:0034774 9.33 INS GIP GCG
4 transport vesicle GO:0030133 9.32 NTS INS
5 extracellular region GO:0005576 9.17 SST SCT PYY NTS INS GIP

Biological processes related to Dumping Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of insulin secretion GO:0050796 9.37 GIP GCG
2 response to amino acid GO:0043200 9.32 SST GIP
3 feeding behavior GO:0007631 9.26 PYY GCG
4 G protein-coupled receptor signaling pathway GO:0007186 9.17 SST SCT PYY NTS INS GIP
5 positive regulation of cAMP-mediated signaling GO:0043950 9.16 SCT GIP
6 response to acidic pH GO:0010447 8.96 SST GIP

Molecular functions related to Dumping Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 G protein-coupled receptor binding GO:0001664 9.16 SCT PYY
2 hormone activity GO:0005179 9.1 SST SCT PYY INS GIP GCG
3 neuropeptide hormone activity GO:0005184 8.96 PYY NTS

Sources for Dumping Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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