MCID: DDN004
MIFTS: 31

Duodenogastric Reflux

Categories: Gastrointestinal diseases

Aliases & Classifications for Duodenogastric Reflux

MalaCards integrated aliases for Duodenogastric Reflux:

Name: Duodenogastric Reflux 12 55 44 15 17 72

Classifications:



External Ids:

Disease Ontology 12 DOID:4071
MeSH 44 D004383
SNOMED-CT 68 9733003
UMLS 72 C0013299

Summaries for Duodenogastric Reflux

MalaCards based summary : Duodenogastric Reflux is related to peptic ulcer disease and dyspepsia. An important gene associated with Duodenogastric Reflux is NTS (Neurotensin), and among its related pathways/superpathways are Signaling by GPCR and Peptide ligand-binding receptors. Affiliated tissues include liver, testes and brain.

Related Diseases for Duodenogastric Reflux

Diseases related to Duodenogastric Reflux via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 121)
# Related Disease Score Top Affiliating Genes
1 peptic ulcer disease 31.4 SCT GAST
2 dyspepsia 31.0 SST CCK
3 atrophic gastritis 30.8 SST GAST
4 cholelithiasis 30.5 SST CCK
5 biliary dyskinesia 30.4 SCT CCK
6 duodenal ulcer 30.2 SST SCT GAST CCK
7 gastroparesis 29.9 MLN GAST CCK
8 stomach disease 29.7 SST MLN GAST
9 irritable bowel syndrome 29.7 PYY MLN CCK
10 postcholecystectomy syndrome 29.6 SST MLN GAST CCK
11 acute pancreatitis 29.6 SST SCT CCK
12 gastroesophageal reflux 29.3 PYY NTS MLN GAST CCK
13 dumping syndrome 28.9 SST SCT PYY NTS
14 pancreatic cancer 28.8 SST SCT NTS GAST CCK
15 constipation 27.4 SST PYY NTS MLN GAST CCK
16 gastrointestinal system disease 27.2 SST SCT PYY MLN GAST CCK
17 duodenal atresia 11.5
18 gastritis 11.1
19 bile reflux 10.9
20 gastrointestinal ulceration, recurrent, with dysfunctional platelets 10.8
21 gastric ulcer 10.8
22 esophagitis 10.7
23 helicobacter pylori infection 10.6
24 barrett esophagus 10.6
25 peptic esophagitis 10.6
26 gallbladder disease 1 10.6
27 cholecystitis 10.4
28 adenocarcinoma 10.4
29 opisthorchiasis 10.4
30 nasal cavity adenocarcinoma 10.3 GAST CCK
31 duodenitis 10.3
32 diphyllobothriasis 10.3 SCT GAST
33 esophageal cancer 10.2
34 choledocholithiasis 10.2
35 48,xyyy 10.2
36 hypotonia 10.2
37 overgrowth syndrome 10.2
38 cataract 14, multiple types 10.2 GAST CCK
39 pain agnosia 10.2 NTS CCK
40 agnosia 10.2 NTS CCK
41 gastrointestinal neuroendocrine benign tumor 10.2 SST GAST
42 gastric neuroendocrine neoplasm 10.2 SST GAST
43 pancreatic steatorrhea 10.2 SCT CCK
44 retinitis pigmentosa 40 10.2 SST GAST
45 pernicious anemia 10.2 SST GAST
46 alcoholic pancreatitis 10.1 SCT CCK
47 exocrine pancreatic insufficiency 10.1 SCT CCK
48 pancreatoblastoma 10.1 SST NTS
49 mixed ductal-endocrine carcinoma 10.1 SST GAST
50 ileum cancer 10.1 SST GAST

Graphical network of the top 20 diseases related to Duodenogastric Reflux:



Diseases related to Duodenogastric Reflux

Symptoms & Phenotypes for Duodenogastric Reflux

Drugs & Therapeutics for Duodenogastric Reflux

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Gastrointestinal Complications in Association With Oropharyngeal and Respiratory Infections in Mechanical Ventilation Unknown status NCT03267693
2 Study of Prognostic Factors for Long Term Results of Total Laparoscopic Fundoplication for Weakly Acidic or Mixed Reflux Completed NCT01741441

Search NIH Clinical Center for Duodenogastric Reflux

Cochrane evidence based reviews: duodenogastric reflux

Genetic Tests for Duodenogastric Reflux

Anatomical Context for Duodenogastric Reflux

MalaCards organs/tissues related to Duodenogastric Reflux:

41
Liver, Testes, Brain, Heart, Small Intestine, Eye, Smooth Muscle

Publications for Duodenogastric Reflux

Articles related to Duodenogastric Reflux:

(show top 50) (show all 833)
# Title Authors PMID Year
1
Effects of duodenogastric reflux on gastrin cells, somatostatin cells and serotonin cells in human antral gastric mucosa. 9 38
15310146 2004
2
Abnormal plasma gut hormones in pathologic duodenogastric reflux and their response to surgery. 9 38
8418694 1993
3
Duodenogastric reflux of bile acids, gastrin and parietal cells, and gastric acid secretion before and 6 months after cholecystectomy. 9 38
2349983 1990
4
An Unfortunate Consequence of Duodenogastric Reflux. 38
31404534 2019
5
Prevalence of Helicobacter pylori is still high among symptomatic Bulgarian children. 38
30585499 2019
6
Late esophagogastric anatomic and functional changes after sleeve gastrectomy and its clinical consequences with regards to gastroesophageal reflux disease. 38
31076757 2019
7
PECULIARITIES OF ACID PRODUCTION AND PATHOGENESIS OF PYLORIC AND PREPYLORIC GASTRIC ULCER COMPLICATIONS. 38
31418722 2019
8
[CLINICAL AND ENDOSCOPIC CHARACTERISTICS OF THE GASTRODUODENAL MUCOSAL LESIONS IN PATIENTS WITH CHRONIC HEPATITIS C INFECTION WITH DIFFERENT BODY MASS STATUS]. 38
31101780 2019
9
Twenty-four-hour oesophageal pH studies in rural Eastern Cape Province, South Africa. 38
30645964 2018
10
[Progress and controversy on diagnosis and treatment of gastric stump cancer]. 38
29774942 2018
11
Non-Helicobacter pylori Gastric Intestinal Metaplasia in Children: A Series of Cases and Review of the Literature. 38
29850294 2018
12
Oxidative stress from reflux esophagitis to esophageal cancer: the alleviation with antioxidants. 38
27109388 2016
13
Influence of duodenogastric reflux in the gastric mucosa histological changes of rats infected with Helicobacter pylori. 38
27679942 2016
14
Durable Flap-Valve Mitigation of Duodenogastric Reflux,  Remnant Gastritis and Dumping Syndrome Following Billroth I Reconstruction. 38
26666548 2016
15
Considerations on risk factors correlated to the occurrence of gastric stump cancer. 38
27453741 2016
16
Current status in remnant gastric cancer after distal gastrectomy. 38
26937131 2016
17
Deoxycholic Acid Could Induce Apoptosis and Trigger Gastric Carcinogenesis on Gastric Epithelial Cells by Quantitative Proteomic Analysis. 38
28070185 2016
18
[Biliary reflux-gastritis: etiology, pathogenesis and modern principles of treatment]. 38
30289664 2016
19
Cholecystectomy and duodenogastric reflux: interacting effects over the gastric mucosa. 38
27917345 2016
20
[MECHANISMS OF GASTRODUODENAL DYSMOTILITY UNDER STRESS]. 38
27301116 2016
21
[Diagnosis of sphincter of Oddi dysfunction in patients with postcholecystectomy syndrome from hepatobiliary scintigraphic findings]. 38
26999929 2015
22
Heterotopic Gastric Mucosa in the Distal Part of Esophagus in a Teenager: Case Report. 38
26496283 2015
23
Common Mechanism of Pathogenesis in Gastrointestinal Diseases Implied by Consistent Efficacy of Single Chinese Medicine Formula: A PRISMA-Compliant Systematic Review and Meta-Analysis. 38
26166106 2015
24
Pepsin and bile acids in saliva in patients with laryngopharyngeal reflux - a prospective comparative study. 38
25516364 2015
25
[DISSEMINATION BY H. PYLORI IN PATIENTS, SUFFERING VARIOUS FORMS OF CHOLECYSTITIS]. 38
26419024 2015
26
Defective upper gastrointestinal function after repair of combined esophageal and duodenal atresia. 38
25840057 2015
27
24-Hour Measurement of Gastric pH in Rural South Africa. 38
25861260 2015
28
Current status of function-preserving surgery for gastric cancer. 38
25516640 2014
29
Potential mechanism of corpus-predominant gastritis after PPI therapy in Helicobacter pylori-positive patients with GERD. 38
25232231 2014
30
Peculiarities of gastrointestinal disease concomitant to heart connective tissue dysplasia in children born from persons exposed to ionizing radiation in childhood after the ChNPP accident. 38
25536566 2014
31
LIM homeodomain transcription factor Isl1 directs normal pyloric development by targeting Gata3. 38
24674670 2014
32
[Gastroesophageal reflux disease associated with duodenogastroesophageal reflux in patients with biliary pathology: the specific features of the course and esophagogastroduodenal microbial biocenosis]. 38
24772502 2014
33
[Indications for surgical treatment of hard scarring gastric ulcers]. 38
24781063 2014
34
Automatic motion analysis system for pyloric flow in ultrasonic videos. 38
24403410 2014
35
Elevated serum dopamine increases while coffee consumption decreases the occurrence of reddish streaks in the intact stomach. 38
23800237 2013
36
Operatively induced chronic reflux in rats: a suitable model for studying esophageal carcinogenesis? 38
24084597 2013
37
A flow visualization model of duodenogastric reflux after esophagectomy with gastric interposition. 38
24067071 2013
38
The role of duodenogastric reflux in formation of precarcinogenic gastric lesions--an experimental study. 38
24069809 2013
39
Spontaneous clearance of Helicobacter pylori after pylorus-preserving gastrectomy for gastric cancer. 38
23673508 2013
40
Late administration of a specific COX-2 inhibitor does not treat and/or prevent progression of gastric tumors in rats submitted to duodenogastric reflux procedure. 38
23743684 2013
41
Weighted cross-correlation based variational optical flow for gastric flow analysis in ultrasonic videos. 38
23635294 2013
42
Endotoxin-induced changes in phospholipid dynamics of the stomach. 38
23158407 2013
43
Atrophic gastritis: Helicobacter pylori versus duodenogastric reflux. 38
26527935 2013
44
Comparative evaluation of intragastric bile acids and hepatobiliary scintigraphy in the diagnosis of duodenogastric reflux. 38
23599645 2013
45
Reactive gastropathy is associated with inflammatory conditions throughout the gastrointestinal tract. 38
22928604 2012
46
Transposed intrathoracic stomach: functional evaluation. 38
23250242 2012
47
Patients with partial gastrectomy and Barrett esophagus are in higher risk to develop esophageal adenocarcinoma than those with Barretts without gastrectomy. 38
22580662 2012
48
Usefulness of pyloric reconstruction without compromising curative resection in gastric cancer treatment. 38
22392089 2012
49
Therapeutic efficacy of acotiamide in patients with functional dyspepsia based on enhanced postprandial gastric accommodation and emptying: randomized controlled study evaluation by real-time ultrasonography. 38
22385472 2012
50
Tracking pylorus in ultrasonic image sequences with edge-based optical flow. 38
22262680 2012

Variations for Duodenogastric Reflux

Expression for Duodenogastric Reflux

Search GEO for disease gene expression data for Duodenogastric Reflux.

Pathways for Duodenogastric Reflux

GO Terms for Duodenogastric Reflux

Cellular components related to Duodenogastric Reflux according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.35 SST SCT PYY GAST CCK
2 extracellular region GO:0005576 9.17 SST SCT PYY NTS MLN GAST

Biological processes related to Duodenogastric Reflux according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 G protein-coupled receptor signaling pathway GO:0007186 9.17 SST SCT PYY NTS MLN GAST
2 digestion GO:0007586 8.96 SST CCK

Molecular functions related to Duodenogastric Reflux according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 G protein-coupled receptor binding GO:0001664 9.16 SCT PYY
2 neuropeptide hormone activity GO:0005184 9.13 PYY NTS CCK
3 hormone activity GO:0005179 9.1 SST SCT PYY MLN GAST CCK

Sources for Duodenogastric Reflux

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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