MCID: DPL007
MIFTS: 28

Duplication of Urethra

Categories: Fetal diseases, Nephrological diseases, Rare diseases, Reproductive diseases
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Aliases & Classifications for Duplication of Urethra

Summaries for Duplication of Urethra

GARD: 19 Duplication of urethra is a very rare condition where there is an extra urethra, instead of the normal one. Urethral duplications can be classified into three types: incomplete urethral duplication (type 1), complete urethral duplication (type 2), and urethral duplication as a result of two bladdersThe urethra is the tube that connects the urinary bladder to the genitals for the removal of fluids from the body. In men, the urethra is a long tube that runs through the penis. In women, the urethra is shorter and emerges above the vaginal opening.

MalaCards based summary: Duplication of Urethra, also known as urethral duplication, is related to vitiligo, progressive, with mental retardation and urethral duplication and hypospadias. Affiliated tissues include uterus, kidney and colon, and related phenotypes are vesicoureteral reflux and epispadias

Orphanet: 58 A rare congenital genitourinary anomaly, encompassing a wide spectrum of anatomic variants in which the urethra is partially or totally duplicated, which may be asymptomatic or cause symptoms such as incontinence, recurrent urinary infections and difficulty urinating.

Related Diseases for Duplication of Urethra

Diseases related to Duplication of Urethra via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 68)
# Related Disease Score Top Affiliating Genes
1 vitiligo, progressive, with mental retardation and urethral duplication 11.1
2 hypospadias 10.4
3 anus, imperforate 10.4
4 urinary tract infection 10.4
5 bladder exstrophy-epispadias-cloacal exstrophy complex 10.3
6 bladder exstrophy 10.2
7 urinary tract infections, recurrent 10.2
8 urethral stricture 10.2
9 urinary tract obstruction 10.2
10 bladder neck obstruction 10.2
11 diphallia 10.2
12 neurogenic bladder 10.1
13 urethral diverticulum 10.1
14 posterior urethral valves 10.1
15 renal hypodysplasia/aplasia 1 10.0
16 benign teratoma 10.0
17 dermoid cyst of ovary 10.0
18 vesicoureteral reflux 10.0
19 anal fistula 9.9
20 cakut 9.9
21 orchitis 9.9
22 pseudohermaphroditism 9.9
23 end stage renal disease 9.9
24 epididymo-orchitis 9.9
25 adult syndrome 9.8
26 autoimmune disease 9.8
27 lipomatosis, multiple 9.8
28 nephrolithiasis, calcium oxalate 9.8
29 pelvic organ prolapse 9.8
30 neural tube defects 9.8
31 vater/vacterl association 9.8
32 vitiligo-associated multiple autoimmune disease susceptibility 6 9.8
33 lipoid congenital adrenal hyperplasia 9.8
34 cryptorchidism, unilateral or bilateral 9.8
35 gastroschisis 9.8
36 hydrops fetalis, nonimmune 9.8
37 pseudovaginal perineoscrotal hypospadias 9.8
38 congenital hemidysplasia with ichthyosiform erythroderma and limb defects 9.8
39 sacral defect with anterior meningocele 9.8
40 vitiligo-associated multiple autoimmune disease susceptibility 1 9.8
41 omphalocele 9.8
42 polycystic kidney disease 9.8
43 urolithiasis 9.8
44 meningocele 9.8
45 tethered spinal cord syndrome 9.8
46 hydronephrosis 9.8
47 chlamydia 9.8
48 bladder calculus 9.8
49 oligohydramnios 9.8
50 balanitis 9.8

Graphical network of the top 20 diseases related to Duplication of Urethra:



Diseases related to Duplication of Urethra

Symptoms & Phenotypes for Duplication of Urethra

Human phenotypes related to Duplication of Urethra:

58 30 (show all 26)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 vesicoureteral reflux 58 30 Frequent (33%) Frequent (79-30%)
HP:0000076
2 epispadias 58 30 Frequent (33%) Frequent (79-30%)
HP:0000039
3 anal atresia 58 30 Occasional (7.5%) Occasional (29-5%)
HP:0002023
4 micropenis 58 30 Occasional (7.5%) Occasional (29-5%)
HP:0000054
5 bifid scrotum 58 30 Occasional (7.5%) Occasional (29-5%)
HP:0000048
6 recurrent urinary tract infections 58 30 Occasional (7.5%) Occasional (29-5%)
HP:0000010
7 dysuria 58 30 Occasional (7.5%) Occasional (29-5%)
HP:0100518
8 gastroschisis 58 30 Occasional (7.5%) Occasional (29-5%)
HP:0001543
9 coronal hypospadias 58 30 Occasional (7.5%) Occasional (29-5%)
HP:0008743
10 uterus didelphys 58 30 Occasional (7.5%) Occasional (29-5%)
HP:0003762
11 septate vagina 58 30 Occasional (7.5%) Occasional (29-5%)
HP:0001153
12 urethral stricture 58 30 Occasional (7.5%) Occasional (29-5%)
HP:0012227
13 distal urethral duplication 58 30 Occasional (7.5%) Occasional (29-5%)
HP:0008706
14 urinary incontinence 58 30 Occasional (7.5%) Occasional (29-5%)
HP:0000020
15 pain 58 30 Occasional (7.5%) Occasional (29-5%)
HP:0012531
16 clitoral hypertrophy 58 30 Occasional (7.5%) Occasional (29-5%)
HP:0008665
17 unilateral renal hypoplasia 58 30 Occasional (7.5%) Occasional (29-5%)
HP:0012583
18 chordee 58 30 Occasional (7.5%) Occasional (29-5%)
HP:0000041
19 rectourethral fistula 58 30 Occasional (7.5%) Occasional (29-5%)
HP:0025407
20 penile hypospadias 58 30 Occasional (7.5%) Occasional (29-5%)
HP:0003244
21 hypertrophy of the urinary bladder 58 30 Occasional (7.5%) Occasional (29-5%)
HP:0008635
22 anuria 58 30 Occasional (7.5%) Occasional (29-5%)
HP:0100519
23 anal fistula 58 30 Occasional (7.5%) Occasional (29-5%)
HP:0010447
24 bladder duplication 58 30 Occasional (7.5%) Occasional (29-5%)
HP:0025489
25 hypospadias 58 Frequent (79-30%)
26 anorectal anomaly 58 Frequent (79-30%)

Drugs & Therapeutics for Duplication of Urethra

Search Clinical Trials, NIH Clinical Center for Duplication of Urethra

Genetic Tests for Duplication of Urethra

Anatomical Context for Duplication of Urethra

Organs/tissues related to Duplication of Urethra:

MalaCards : Uterus, Kidney, Colon

Publications for Duplication of Urethra

Articles related to Duplication of Urethra:

(show top 50) (show all 292)
# Title Authors PMID Year
1
Technical details and long-term outcomes of P.A.D.U.A. for congenital urethral narrowing; a case series and review of the literature. 62
36424292 2022
2
Anorectal malformation, urethral duplication, occult spinal dysraphism (ARM-UD-OSD): a challenging uncommon association. 62
35882671 2022
3
Congenital Anterior Urethral Diverticulum in Identical Twins. 62
36244471 2022
4
Congenital anterior urethral valves and diverticulum: A case series and association with posterior urethral valves. 62
36123286 2022
5
Missed urethral duplication associated with hypospadias, post-hypospadias repair urethral stenosis, and recurrent urinary tract infections in an adult: a case report. 62
36180877 2022
6
Urethral duplication as cause of incontinence in a 5-years-old female: Surgical approach. 62
36075828 2022
7
Urethral duplication with bilateral megaureter and bladder outlet obstruction: unusual case managed by PADUA technique. 62
35792899 2022
8
Robotic-assisted laparoscopic repair of a congenital rectourethral fistula with duplicated urethra. 62
35525825 2022
9
Female pseudohermaphroditism with urethral duplication: A delayed presentation in adulthood. 62
35400864 2022
10
Duplicate urethra communicating with seminal vesicles: A rare case report. 62
34976738 2022
11
An Unusual Case of Type A Posterior Cloaca Associated with 46XX Disorder of Sexual Differentiation with Y Duplication of Urethra. 62
35937130 2022
12
Urethral duplication in an adult male: anatomic variants and operative approach to reconstruction. 62
35150227 2022
13
Misdiagnosis of Congenital Posterior Urethroperineal Fistula and Comparison With Urethral Duplications and Rectourethral Fistula. 62
34606879 2021
14
Bladder and urethral duplication and a bladder exstrophy plate with omphalocele in a female child. 62
34285880 2021
15
Surgical Correction of True Diphallia in a Newborn Male. 62
34284008 2021
16
Duplication of the urethra in an adult male presenting with scrotal fistula: a rare case report. 62
34603685 2021
17
Working classification and the quest for an effective, reconstructive management strategy in Y duplication of male urethra. 62
33707130 2021
18
Simultaneous Endoscopic Management of Urethral Duplication and Postposterior Sagittal Anorectoplasty Urethral Diverticulum in a Boy with Anorectal Malformation. 62
34321796 2021
19
Urethral duplication in a 1 year old: a rare case report. 62
34011667 2021
20
Urethral duplication with congenital megacystis and obstructive megaureter - A rare association. 62
33850360 2021
21
Partial urethral duplication in a cat. 62
33269965 2020
22
Urethral Multiplicity: When Two Are Better Than One. 62
32717245 2020
23
Urethral duplication in male children: A study of 12 cases. 62
32063365 2020
24
Isolated coronal urethral duplication in an adolescent presenting with enuresis. 62
33231016 2020
25
Type IIB urethral duplication in young adult-A case report. 62
32514325 2020
26
Urethral Duplication With Heterotopic Colonic Epithelium Presenting as Penoscrotal Mass: A Rare Association. 62
32333986 2020
27
Urethral Duplication With clitoral Voiding: A Rare Presentation. 62
32333989 2020
28
Urethral duplication-Epidemiology, diagnosis, and treatment in a case series of 19 patients. 62
32197934 2020
29
Urethral duplication in male epispadias: a very uncommon association. 62
30957471 2020
30
Epispadias associated with urethral duplication: Our practice. 62
32473552 2020
31
Complete Urethral Duplication: Case Report and Literature Review. 62
32158721 2020
32
Urethral duplication with rectourethral fistula: Review of two cases. 62
32015628 2020
33
Congenital prepubic sinus with dorsal penile curvature: a case report and literature review. 62
31640609 2019
34
Urethral Duplication in Children: Experience of Twenty Cases. 62
31571759 2019
35
Urethral duplication: a case for careful examination. 62
29728420 2019
36
Complete duplicated hindgut anomaly presenting in adolescence: Six Ostia in perineum. 62
31367078 2019
37
Congenital prepubic sinus-An aborted dorsal urethral duplication or a cloacal remnant? 62
30115449 2019
38
Diphallia, Double Bladder, and Two Hemiscrotums: A Case Report. 62
31135983 2019
39
Incomplete Urethral Duplication Associated with a Dermoid Cyst within a Vascular Hamartoma in a Female Dog. 62
31151175 2019
40
Hypospadiac Urethral Duplication- A Rare Variant and Novel use of Snodgrass Urethroplasty. 62
31105403 2019
41
Urethral duplication in a child with VATER association. 62
30534525 2019
42
[Application of disposable oval circumcision anastomat in pediatric urology]. 62
30669751 2019
43
Johanson-Blizzard syndrome with associated urogenital anomalies. 62
30097546 2018
44
Laparoscopic excision of complete bladder duplication in a 1-year-old male. 62
29934031 2018
45
Urodynamic performance in boys with Y-type urethral duplication. 62
28629820 2018
46
Spinal lipoma associated with urethral duplication. 62
29888176 2018
47
Case of urethral duplication seen by voiding urosonography. 62
29216522 2018
48
An unusual presentation of urethral duplication presenting with chronic bladder retention, left scrotal transposition and left renal agenesis. 62
29064654 2018
49
Y-type urethral duplication with rectal implantation of the urethra: Which is the best approach? 62
29175024 2018
50
Urethral Triplication Without Bladder Duplication: Endourologic Diagnosis and Management. 62
29675475 2018

Variations for Duplication of Urethra

Expression for Duplication of Urethra

Search GEO for disease gene expression data for Duplication of Urethra.

Pathways for Duplication of Urethra

GO Terms for Duplication of Urethra

Sources for Duplication of Urethra

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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