Duplication of Urethra disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

GARD: ¹⁹ Duplication of urethra is a very rare condition where there is an extra urethra, instead of the normal one. Urethral duplications can be classified into three types: incomplete urethral duplication (type 1), complete urethral duplication (type 2), and urethral duplication as a result of two bladdersThe urethra is the tube that connects the urinary bladder to the genitals for the removal of fluids from the body. In men, the urethra is a long tube that runs through the penis. In women, the urethra is shorter and emerges above the vaginal opening.

MalaCards based summary: Duplication of Urethra, also known as urethral duplication, is related to vitiligo, progressive, with mental retardation and urethral duplication and hypospadias. Affiliated tissues include uterus, kidney and colon, and related phenotypes are vesicoureteral reflux and epispadias

Orphanet: ⁵⁸ A rare congenital genitourinary anomaly, encompassing a wide spectrum of anatomic variants in which the urethra is partially or totally duplicated, which may be asymptomatic or cause symptoms such as incontinence, recurrent urinary infections and difficulty urinating.

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Related Diseases for Duplication of Urethra

Diseases related to Duplication of Urethra via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 68)

#	Related Disease	Score
1	vitiligo, progressive, with mental retardation and urethral duplication	11.1
2	hypospadias	10.4
3	anus, imperforate	10.4
4	urinary tract infection	10.4
5	bladder exstrophy-epispadias-cloacal exstrophy complex	10.3
6	bladder exstrophy	10.2
7	urinary tract infections, recurrent	10.2
8	urethral stricture	10.2
9	urinary tract obstruction	10.2
10	bladder neck obstruction	10.2
11	diphallia	10.2
12	neurogenic bladder	10.1
13	urethral diverticulum	10.1
14	posterior urethral valves	10.1
15	renal hypodysplasia/aplasia 1	10.0
16	benign teratoma	10.0
17	dermoid cyst of ovary	10.0
18	vesicoureteral reflux	10.0
19	anal fistula	9.9
20	cakut	9.9
21	orchitis	9.9
22	pseudohermaphroditism	9.9
23	end stage renal disease	9.9
24	epididymo-orchitis	9.9
25	adult syndrome	9.8
26	autoimmune disease	9.8
27	lipomatosis, multiple	9.8
28	nephrolithiasis, calcium oxalate	9.8
29	pelvic organ prolapse	9.8
30	neural tube defects	9.8
31	vater/vacterl association	9.8
32	vitiligo-associated multiple autoimmune disease susceptibility 6	9.8
33	lipoid congenital adrenal hyperplasia	9.8
34	cryptorchidism, unilateral or bilateral	9.8
35	gastroschisis	9.8
36	hydrops fetalis, nonimmune	9.8
37	pseudovaginal perineoscrotal hypospadias	9.8
38	congenital hemidysplasia with ichthyosiform erythroderma and limb defects	9.8
39	sacral defect with anterior meningocele	9.8
40	vitiligo-associated multiple autoimmune disease susceptibility 1	9.8
41	omphalocele	9.8
42	polycystic kidney disease	9.8
43	urolithiasis	9.8
44	meningocele	9.8
45	tethered spinal cord syndrome	9.8
46	hydronephrosis	9.8
47	chlamydia	9.8
48	bladder calculus	9.8
49	oligohydramnios	9.8
50	balanitis	9.8

Graphical network of the top 20 diseases related to Duplication of Urethra:

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Symptoms & Phenotypes for Duplication of Urethra

Human phenotypes related to Duplication of Urethra:

⁵⁸ ³⁰ (show all 26)

#	Description	HPO Frequency	Orphanet Frequency	HPO Source Accession
1	vesicoureteral reflux ⁵⁸ ³⁰	Frequent (33%)	Frequent (79-30%)	HP:0000076
2	epispadias ⁵⁸ ³⁰	Frequent (33%)	Frequent (79-30%)	HP:0000039
3	anal atresia ⁵⁸ ³⁰	Occasional (7.5%)	Occasional (29-5%)	HP:0002023
4	micropenis ⁵⁸ ³⁰	Occasional (7.5%)	Occasional (29-5%)	HP:0000054
5	bifid scrotum ⁵⁸ ³⁰	Occasional (7.5%)	Occasional (29-5%)	HP:0000048
6	recurrent urinary tract infections ⁵⁸ ³⁰	Occasional (7.5%)	Occasional (29-5%)	HP:0000010
7	dysuria ⁵⁸ ³⁰	Occasional (7.5%)	Occasional (29-5%)	HP:0100518
8	gastroschisis ⁵⁸ ³⁰	Occasional (7.5%)	Occasional (29-5%)	HP:0001543
9	coronal hypospadias ⁵⁸ ³⁰	Occasional (7.5%)	Occasional (29-5%)	HP:0008743
10	uterus didelphys ⁵⁸ ³⁰	Occasional (7.5%)	Occasional (29-5%)	HP:0003762
11	septate vagina ⁵⁸ ³⁰	Occasional (7.5%)	Occasional (29-5%)	HP:0001153
12	urethral stricture ⁵⁸ ³⁰	Occasional (7.5%)	Occasional (29-5%)	HP:0012227
13	distal urethral duplication ⁵⁸ ³⁰	Occasional (7.5%)	Occasional (29-5%)	HP:0008706
14	urinary incontinence ⁵⁸ ³⁰	Occasional (7.5%)	Occasional (29-5%)	HP:0000020
15	pain ⁵⁸ ³⁰	Occasional (7.5%)	Occasional (29-5%)	HP:0012531
16	clitoral hypertrophy ⁵⁸ ³⁰	Occasional (7.5%)	Occasional (29-5%)	HP:0008665
17	unilateral renal hypoplasia ⁵⁸ ³⁰	Occasional (7.5%)	Occasional (29-5%)	HP:0012583
18	chordee ⁵⁸ ³⁰	Occasional (7.5%)	Occasional (29-5%)	HP:0000041
19	rectourethral fistula ⁵⁸ ³⁰	Occasional (7.5%)	Occasional (29-5%)	HP:0025407
20	penile hypospadias ⁵⁸ ³⁰	Occasional (7.5%)	Occasional (29-5%)	HP:0003244
21	hypertrophy of the urinary bladder ⁵⁸ ³⁰	Occasional (7.5%)	Occasional (29-5%)	HP:0008635
22	anuria ⁵⁸ ³⁰	Occasional (7.5%)	Occasional (29-5%)	HP:0100519
23	anal fistula ⁵⁸ ³⁰	Occasional (7.5%)	Occasional (29-5%)	HP:0010447
24	bladder duplication ⁵⁸ ³⁰	Occasional (7.5%)	Occasional (29-5%)	HP:0025489
25	hypospadias ⁵⁸		Frequent (79-30%)
26	anorectal anomaly ⁵⁸		Frequent (79-30%)

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Drugs & Therapeutics for Duplication of Urethra

Search Clinical Trials, NIH Clinical Center for Duplication of Urethra

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Genetic Tests for Duplication of Urethra

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Anatomical Context for Duplication of Urethra

Organs/tissues related to Duplication of Urethra:

MalaCards : Uterus, Kidney, Colon

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Publications for Duplication of Urethra

Articles related to Duplication of Urethra:

(show top 50) (show all 292)

#	Title	Authors	PMID	Year
1	Technical details and long-term outcomes of P.A.D.U.A. for congenital urethral narrowing; a case series and review of the literature. ⁶²	Danzig MR...Ellison JS	36424292	2022
2	Anorectal malformation, urethral duplication, occult spinal dysraphism (ARM-UD-OSD): a challenging uncommon association. ⁶²	Lena F...Mosiello G	35882671	2022
3	Congenital Anterior Urethral Diverticulum in Identical Twins. ⁶²	Wei N...Dyer L	36244471	2022
4	Congenital anterior urethral valves and diverticulum: A case series and association with posterior urethral valves. ⁶²	Menon P...Rao KLN	36123286	2022
5	Missed urethral duplication associated with hypospadias, post-hypospadias repair urethral stenosis, and recurrent urinary tract infections in an adult: a case report. ⁶²	Hosseini J...Mirjalili A	36180877	2022
6	Urethral duplication as cause of incontinence in a 5-years-old female: Surgical approach. ⁶²	Jamaer C...Spinoit AF	36075828	2022
7	Urethral duplication with bilateral megaureter and bladder outlet obstruction: unusual case managed by PADUA technique. ⁶²	Escolino M...Esposito C	35792899	2022
8	Robotic-assisted laparoscopic repair of a congenital rectourethral fistula with duplicated urethra. ⁶²	Bhalla RG...Thomas JC	35525825	2022
9	Female pseudohermaphroditism with urethral duplication: A delayed presentation in adulthood. ⁶²	Deshpande AV...Hazare JD	35400864	2022
10	Duplicate urethra communicating with seminal vesicles: A rare case report. ⁶²	Zhou T...Wu Z	34976738	2022
11	An Unusual Case of Type A Posterior Cloaca Associated with 46XX Disorder of Sexual Differentiation with Y Duplication of Urethra. ⁶²	Gupta RK...Shah RS	35937130	2022
12	Urethral duplication in an adult male: anatomic variants and operative approach to reconstruction. ⁶²	Farrell MR...Vanni AJ	35150227	2022
13	Misdiagnosis of Congenital Posterior Urethroperineal Fistula and Comparison With Urethral Duplications and Rectourethral Fistula. ⁶²	Cheng JW...Rice-Townsend SE	34606879	2021
14	Bladder and urethral duplication and a bladder exstrophy plate with omphalocele in a female child. ⁶²	Freitas Filho LG...Budib LJ	34285880	2021
15	Surgical Correction of True Diphallia in a Newborn Male. ⁶²	Samadi Y...Al-Omar O	34284008	2021
16	Duplication of the urethra in an adult male presenting with scrotal fistula: a rare case report. ⁶²	Tlili G...Saad H	34603685	2021
17	Working classification and the quest for an effective, reconstructive management strategy in Y duplication of male urethra. ⁶²	Kurian JJ...Sen S	33707130	2021
18	Simultaneous Endoscopic Management of Urethral Duplication and Postposterior Sagittal Anorectoplasty Urethral Diverticulum in a Boy with Anorectal Malformation. ⁶²	Ratan SK...Aggarwal SK	34321796	2021
19	Urethral duplication in a 1 year old: a rare case report. ⁶²	Kallepalli DVS...Bharathi S	34011667	2021
20	Urethral duplication with congenital megacystis and obstructive megaureter - A rare association. ⁶²	Singh P...Biju SP	33850360	2021
21	Partial urethral duplication in a cat. ⁶²	Power AM...Thomas D	33269965	2020
22	Urethral Multiplicity: When Two Are Better Than One. ⁶²	Janssen K...Kirsch A	32717245	2020
23	Urethral duplication in male children: A study of 12 cases. ⁶²	Kang SK...Kim SW	32063365	2020
24	Isolated coronal urethral duplication in an adolescent presenting with enuresis. ⁶²	Bokhari AA...Adam A	33231016	2020
25	Type IIB urethral duplication in young adult-A case report. ⁶²	Foladi N...Karimy MJ	32514325	2020
26	Urethral Duplication With Heterotopic Colonic Epithelium Presenting as Penoscrotal Mass: A Rare Association. ⁶²	Danish N...Yadav P	32333986	2020
27	Urethral Duplication With clitoral Voiding: A Rare Presentation. ⁶²	Sharma AP...Parmar KM	32333989	2020
28	Urethral duplication-Epidemiology, diagnosis, and treatment in a case series of 19 patients. ⁶²	Guglielmetti LC...Vuille-Dit-Bille RN	32197934	2020
29	Urethral duplication in male epispadias: a very uncommon association. ⁶²	Caione P...Messina M	30957471	2020
30	Epispadias associated with urethral duplication: Our practice. ⁶²	Polukhov R...Baghirli M	32473552	2020
31	Complete Urethral Duplication: Case Report and Literature Review. ⁶²	Suoub M...Sawaqed F	32158721	2020
32	Urethral duplication with rectourethral fistula: Review of two cases. ⁶²	Saran RK...Takhar RP	32015628	2020
33	Congenital prepubic sinus with dorsal penile curvature: a case report and literature review. ⁶²	Wang C...Ma X	31640609	2019
34	Urethral Duplication in Children: Experience of Twenty Cases. ⁶²	Wani SA...Deepak J	31571759	2019
35	Urethral duplication: a case for careful examination. ⁶²	Taghavi K...Mushtaq I	29728420	2019
36	Complete duplicated hindgut anomaly presenting in adolescence: Six Ostia in perineum. ⁶²	Nayyar R...Krishna A	31367078	2019
37	Congenital prepubic sinus-An aborted dorsal urethral duplication or a cloacal remnant? ⁶²	Nazir Z...Qamar J	30115449	2019
38	Diphallia, Double Bladder, and Two Hemiscrotums: A Case Report. ⁶²	Dunn D...Fine RG	31135983	2019
39	Incomplete Urethral Duplication Associated with a Dermoid Cyst within a Vascular Hamartoma in a Female Dog. ⁶²	Clancy CS...Van Wettere AJ	31151175	2019
40	Hypospadiac Urethral Duplication- A Rare Variant and Novel use of Snodgrass Urethroplasty. ⁶²	Saxena R...Sinha A	31105403	2019
41	Urethral duplication in a child with VATER association. ⁶²	Nerli RB...Hiremath MB	30534525	2019
42	[Application of disposable oval circumcision anastomat in pediatric urology]. ⁶²	Feng DC...Hu DH	30669751	2019
43	Johanson-Blizzard syndrome with associated urogenital anomalies. ⁶²	Sood A...Lakshmanan Y	30097546	2018
44	Laparoscopic excision of complete bladder duplication in a 1-year-old male. ⁶²	Kord E...Neheman A	29934031	2018
45	Urodynamic performance in boys with Y-type urethral duplication. ⁶²	Zhang Y...Song H	28629820	2018
46	Spinal lipoma associated with urethral duplication. ⁶²	Freitas Filho LG...Budib LJ	29888176	2018
47	Case of urethral duplication seen by voiding urosonography. ⁶²	Patel H...Chow JS	29216522	2018
48	An unusual presentation of urethral duplication presenting with chronic bladder retention, left scrotal transposition and left renal agenesis. ⁶²	Macedo A...Garrone G	29064654	2018
49	Y-type urethral duplication with rectal implantation of the urethra: Which is the best approach? ⁶²	Macedo A...Garrone G	29175024	2018
50	Urethral Triplication Without Bladder Duplication: Endourologic Diagnosis and Management. ⁶²	Parente A...Angulo JM	29675475	2018

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Genes for Duplication of Urethra

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Variations for Duplication of Urethra

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Expression for Duplication of Urethra

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MCID: DPL007 MIFTS: 28	Duplication of Urethra Categories: Fetal diseases, Nephrological diseases, Rare diseases, Reproductive diseases	Data Licensing For inquiries, contact: [email protected]
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Duplication of Urethra

Aliases & Classifications for Duplication of Urethra

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Summaries for Duplication of Urethra

Related Diseases for Duplication of Urethra

Diseases related to Duplication of Urethra via text searches within MalaCards or GeneCards Suite gene sharing:

Graphical network of the top 20 diseases related to Duplication of Urethra:

Symptoms & Phenotypes for Duplication of Urethra

Human phenotypes related to Duplication of Urethra:

Drugs & Therapeutics for Duplication of Urethra

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Anatomical Context for Duplication of Urethra

Organs/tissues related to Duplication of Urethra:

Publications for Duplication of Urethra

Articles related to Duplication of Urethra:

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