Dyskeratosis Congenita Autosomal Dominant disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

DKCA MCID: DYS039 MIFTS: 32	Dyskeratosis Congenita Autosomal Dominant (DKCA) Categories: Blood diseases, Bone diseases, Eye diseases, Fetal diseases, Genetic diseases, Immune diseases, Liver diseases, Neuronal diseases, Rare diseases, Skin diseases
Genes Variations Tissues Related diseases Publications Pathways Expand all tables

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Aliases & Classifications for Dyskeratosis Congenita Autosomal Dominant

MalaCards integrated aliases for Dyskeratosis Congenita Autosomal Dominant:

Name: Dyskeratosis Congenita Autosomal Dominant ⁵³ ²⁹ ⁶

Dyskeratosis Congenita, Autosomal Dominant ⁵⁵ ⁷³

Autosomal Dominant Dyskeratosis Congenita ⁵³

Dyskeratosis Congenita Scoggins Type ⁵³

Dkca ⁵³

Classifications:

MalaCards categories:
Global: Rare diseases Genetic diseases Fetal diseases
Anatomical: Skin diseases Blood diseases Eye diseases Neuronal diseases Bone diseases Immune diseases Liver diseases

See all MalaCards categories (disease lists)

External Ids:

UMLS ⁷³ C1851970

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Summaries for Dyskeratosis Congenita Autosomal Dominant

MalaCards based summary : Dyskeratosis Congenita Autosomal Dominant, also known as dyskeratosis congenita, autosomal dominant, is related to dyskeratosis congenita, autosomal dominant 1 and dyskeratosis congenita, autosomal dominant 6. An important gene associated with Dyskeratosis Congenita Autosomal Dominant is TERT (Telomerase Reverse Transcriptase), and among its related pathways/superpathways are Chromosome Maintenance and Lung fibrosis. Affiliated tissues include bone, skin and liver.

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Related Diseases for Dyskeratosis Congenita Autosomal Dominant

Diseases in the Dyskeratosis Congenita family:

Dyskeratosis Congenita, Autosomal Dominant 1	Dyskeratosis Congenita, Autosomal Recessive 1
Dyskeratosis Congenita, Autosomal Recessive 2	Dyskeratosis Congenita, Autosomal Recessive 3
Dyskeratosis Congenita, Autosomal Dominant 2	Dyskeratosis Congenita, Autosomal Dominant 3
Dyskeratosis Congenita, Autosomal Recessive 5	Dyskeratosis Congenita, Autosomal Recessive 6
Dyskeratosis Congenita, Autosomal Dominant 6	Dyskeratosis Congenita Autosomal Dominant
Dyskeratosis Congenita Autosomal Recessive

Diseases related to Dyskeratosis Congenita Autosomal Dominant via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 14)

#	Related Disease	Score	Top Affiliating Genes
1	dyskeratosis congenita, autosomal dominant 1	33.6	TERC TERT TINF2
2	dyskeratosis congenita, autosomal dominant 6	33.5	ACD CARMIL2 PARD6A
3	dyskeratosis congenita, autosomal recessive 5	33.1	RTEL1 RTEL1-TNFRSF6B
4	revesz syndrome	33.0	TERC TERT TINF2
5	dyskeratosis congenita	29.6	ACD PARD6A RTEL1 RTEL1-TNFRSF6B TERC TERT
6	dyskeratosis congenita, autosomal dominant 2	12.7
7	dyskeratosis congenita, autosomal dominant 3	12.7
8	inherited bone marrow failure syndromes	10.0	TERC TERT
9	pulmonary fibrosis and/or bone marrow failure, telomere-related, 3	9.9	RTEL1 RTEL1-TNFRSF6B
10	cervical intraepithelial neoplasia	9.9	TERC TERT
11	pulmonary fibrosis, idiopathic	9.8	RTEL1 TERC TERT
12	pulmonary fibrosis	9.8	RTEL1 TERC TERT TINF2
13	aplastic anemia	9.7	RTEL1 TERC TERT TINF2
14	dyskeratosis congenita autosomal recessive	9.2	ACD CARMIL2 PARD6A RTEL1 RTEL1-TNFRSF6B TERT

Graphical network of the top 20 diseases related to Dyskeratosis Congenita Autosomal Dominant:

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Symptoms & Phenotypes for Dyskeratosis Congenita Autosomal Dominant

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Drugs & Therapeutics for Dyskeratosis Congenita Autosomal Dominant

Search Clinical Trials , NIH Clinical Center for Dyskeratosis Congenita Autosomal Dominant

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Genetic Tests for Dyskeratosis Congenita Autosomal Dominant

Genetic tests related to Dyskeratosis Congenita Autosomal Dominant:

#	Genetic test	Affiliating Genes
1	Dyskeratosis Congenita Autosomal Dominant ²⁹	TERC TERT TINF2

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Anatomical Context for Dyskeratosis Congenita Autosomal Dominant

MalaCards organs/tissues related to Dyskeratosis Congenita Autosomal Dominant:

⁴¹

Bone, Skin, Liver, Eye, Bone Marrow

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Publications for Dyskeratosis Congenita Autosomal Dominant

Articles related to Dyskeratosis Congenita Autosomal Dominant:

#	Title	Authors	Year
1	Bilateral retinal vasculopathy associated with autosomal dominant dyskeratosis congenita. ( 23661544 )	Vaz-Pereira S....Mufti G.J.	2013
2	Retinal vasculopathy in autosomal dominant dyskeratosis congenita due to TINF2 mutation. ( 23094712 )	Gleeson M....Smith O.P.	2012
3	Retinal vasculopathy in a family with autosomal dominant dyskeratosis congenita. ( 19852575 )	Johnson C.A....Pulido J.S.	2009
4	Expanding the clinical phenotype of autosomal dominant dyskeratosis congenita caused by TERT mutations. ( 18460650 )		2008
5	Haploinsufficiency of telomerase reverse transcriptase leads to anticipation in autosomal dominant dyskeratosis congenita. ( 16247010 )	Armanios M....Greider C.W.	2005
6	Association of immune abnormalities with telomere shortening in autosomal-dominant dyskeratosis congenita. ( 15238429 )		2005
7	The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita. ( 11574891 )	Vulliamy T....Dokal I.	2001

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Genes for Dyskeratosis Congenita Autosomal Dominant

Genes related to Dyskeratosis Congenita Autosomal Dominant (3 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	TERT	Telomerase Reverse Transcriptase	Protein Coding	531.18	Pathogenic ⁶ Genetic Tests ²⁹ GeneCards inferred via : Disorders Variants (show sections)	20301779 21610750
2	TINF2	TERF1 Interacting Nuclear Factor 2	Protein Coding	529.19	Pathogenic ⁶ Genetic Tests ²⁹ GeneCards inferred via : Disorders Variants (show sections)	20301779 21610750
3	TERC	Telomerase RNA Component	RNA Gene	519.47	Pathogenic ⁶ Genetic Tests ²⁹ GeneCards inferred via : Variants (show sections)	20301779 21610750 11574891
4	ACD	ACD, Shelterin Complex Subunit And Telomerase Recruitment Factor	Protein Coding	28.74	GeneCards inferred via : Disorders Variants (show sections)
5	RTEL1	Regulator Of Telomere Elongation Helicase 1	Protein Coding	27.68	GeneCards inferred via : Disorders Variants (show sections)
6	PARD6A	Par-6 Family Cell Polarity Regulator Alpha	Protein Coding	18.76	GeneCards inferred via : Variants (show sections)
7	CARMIL2	Capping Protein Regulator And Myosin 1 Linker 2	Protein Coding	18.3	GeneCards inferred via : Variants (show sections)
8	RTEL1-TNFRSF6B	RTEL1-TNFRSF6B Readthrough (NMD Candidate)	RNA Gene	17.96	GeneCards inferred via : Variants (show sections)

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Variations for Dyskeratosis Congenita Autosomal Dominant

ClinVar genetic disease variations for Dyskeratosis Congenita Autosomal Dominant:

⁶ (show top 50) (show all 179)

#	Gene	Variation	Type	Significance	SNP ID	Assembly	Location
1	TINF2	NM_001099274.1(TINF2): c.838A> G (p.Lys280Glu)	single nucleotide variant	Pathogenic	rs121918543	GRCh37	Chromosome 14, 24709848: 24709848
2	TINF2	NM_001099274.1(TINF2): c.838A> G (p.Lys280Glu)	single nucleotide variant	Pathogenic	rs121918543	GRCh38	Chromosome 14, 24240642: 24240642
3	TINF2	NM_001099274.1(TINF2): c.844C> A (p.Arg282Ser)	single nucleotide variant	Pathogenic	rs121918545	GRCh37	Chromosome 14, 24709842: 24709842
4	TINF2	NM_001099274.1(TINF2): c.844C> A (p.Arg282Ser)	single nucleotide variant	Pathogenic	rs121918545	GRCh38	Chromosome 14, 24240636: 24240636
5	TINF2	NM_001099274.1(TINF2): c.844C> T (p.Arg282Cys)	single nucleotide variant	Pathogenic	rs121918545	GRCh37	Chromosome 14, 24709842: 24709842
6	TINF2	NM_001099274.1(TINF2): c.844C> T (p.Arg282Cys)	single nucleotide variant	Pathogenic	rs121918545	GRCh38	Chromosome 14, 24240636: 24240636
7	TERC	NR_001566.1(TERC): n.374_1194del821	deletion	Pathogenic		GRCh37	Chromosome 3, 169481655: 169482475
8	TERC	NR_001566.1(TERC): n.374_1194del821	deletion	Pathogenic		GRCh38	Chromosome 3, 169763867: 169764687
9	TERC	NR_001566.1(TERC): n.408C> G	single nucleotide variant	Pathogenic	rs199422284	GRCh37	Chromosome 3, 169482441: 169482441
10	TERC	NR_001566.1(TERC): n.408C> G	single nucleotide variant	Pathogenic	rs199422284	GRCh38	Chromosome 3, 169764653: 169764653
11	TERC	NR_001566.1(TERC): n.107_108delGCinsAG	indel	Pathogenic	rs199476393	GRCh37	Chromosome 3, 169482741: 169482742
12	TERC	NR_001566.1(TERC): n.107_108delGCinsAG	indel	Pathogenic	rs199476393	GRCh38	Chromosome 3, 169764953: 169764954
13	TERC	NR_001566.1(TERC): n.204C> G	single nucleotide variant	Pathogenic	rs199422277	GRCh37	Chromosome 3, 169482645: 169482645
14	TERC	NR_001566.1(TERC): n.204C> G	single nucleotide variant	Pathogenic	rs199422277	GRCh38	Chromosome 3, 169764857: 169764857
15	TERC	NR_001566.1(TERC): n.58G> A	single nucleotide variant	Benign	rs113487931	GRCh37	Chromosome 3, 169482791: 169482791
16	TERC	NR_001566.1(TERC): n.58G> A	single nucleotide variant	Benign	rs113487931	GRCh38	Chromosome 3, 169765003: 169765003
17	TERC	NR_001566.1(TERC): n.116C> T	single nucleotide variant	Pathogenic	rs199422272	GRCh37	Chromosome 3, 169482733: 169482733
18	TERC	NR_001566.1(TERC): n.116C> T	single nucleotide variant	Pathogenic	rs199422272	GRCh38	Chromosome 3, 169764945: 169764945
19	TERT	NM_198253.2(TERT): c.2706G> C (p.Lys902Asn)	single nucleotide variant	Pathogenic	rs121918665	GRCh37	Chromosome 5, 1264656: 1264656
20	TERT	NM_198253.2(TERT): c.2706G> C (p.Lys902Asn)	single nucleotide variant	Pathogenic	rs121918665	GRCh38	Chromosome 5, 1264541: 1264541
21	TERC	NR_001566.1(TERC): n.54_57delAACT	deletion	Pathogenic	rs199422263	GRCh37	Chromosome 3, 169482792: 169482795
22	TERC	NR_001566.1(TERC): n.54_57delAACT	deletion	Pathogenic	rs199422263	GRCh38	Chromosome 3, 169765004: 169765007
23	TINF2	NM_001099274.1(TINF2): c.706C> T (p.Pro236Ser)	single nucleotide variant	Likely benign	rs199422321	GRCh37	Chromosome 14, 24709980: 24709980
24	TINF2	NM_001099274.1(TINF2): c.706C> T (p.Pro236Ser)	single nucleotide variant	Likely benign	rs199422321	GRCh38	Chromosome 14, 24240774: 24240774
25	TINF2	NM_001099274.1(TINF2): c.734C> A (p.Ser245Tyr)	single nucleotide variant	Conflicting interpretations of pathogenicity	rs142777869	GRCh37	Chromosome 14, 24709952: 24709952
26	TINF2	NM_001099274.1(TINF2): c.734C> A (p.Ser245Tyr)	single nucleotide variant	Conflicting interpretations of pathogenicity	rs142777869	GRCh38	Chromosome 14, 24240746: 24240746
27	TINF2	NM_001099274.1(TINF2): c.838A> T (p.Lys280Ter)	single nucleotide variant	Pathogenic	rs121918543	GRCh37	Chromosome 14, 24709848: 24709848
28	TINF2	NM_001099274.1(TINF2): c.838A> T (p.Lys280Ter)	single nucleotide variant	Pathogenic	rs121918543	GRCh38	Chromosome 14, 24240642: 24240642
29	TINF2	NM_001099274.1(TINF2): c.841G> A (p.Glu281Lys)	single nucleotide variant	Likely benign	rs199422322	GRCh37	Chromosome 14, 24709845: 24709845
30	TINF2	NM_001099274.1(TINF2): c.841G> A (p.Glu281Lys)	single nucleotide variant	Likely benign	rs199422322	GRCh38	Chromosome 14, 24240639: 24240639
31	TINF2	NM_001099274.1(TINF2): c.847C> G (p.Pro283Ala)	single nucleotide variant	Pathogenic	rs199422311	GRCh37	Chromosome 14, 24709839: 24709839
32	TINF2	NM_001099274.1(TINF2): c.847C> G (p.Pro283Ala)	single nucleotide variant	Pathogenic	rs199422311	GRCh38	Chromosome 14, 24240633: 24240633
33	TINF2	NM_001099274.1(TINF2): c.847C> T (p.Pro283Ser)	single nucleotide variant	Pathogenic	rs199422311	GRCh37	Chromosome 14, 24709839: 24709839
34	TINF2	NM_001099274.1(TINF2): c.847C> T (p.Pro283Ser)	single nucleotide variant	Pathogenic	rs199422311	GRCh38	Chromosome 14, 24240633: 24240633
35	TINF2	NM_001099274.1(TINF2): c.848C> A (p.Pro283His)	single nucleotide variant	Pathogenic	rs199422313	GRCh37	Chromosome 14, 24709838: 24709838
36	TINF2	NM_001099274.1(TINF2): c.848C> A (p.Pro283His)	single nucleotide variant	Pathogenic	rs199422313	GRCh38	Chromosome 14, 24240632: 24240632
37	TINF2	NM_001099274.1(TINF2): c.849dupC (p.Thr284Hisfs)	duplication	Pathogenic	rs199422315	GRCh37	Chromosome 14, 24709837: 24709837
38	TINF2	NM_001099274.1(TINF2): c.849dupC (p.Thr284Hisfs)	duplication	Pathogenic	rs199422315	GRCh38	Chromosome 14, 24240631: 24240631
39	TINF2	NM_001099274.1(TINF2): c.850A> G (p.Thr284Ala)	single nucleotide variant	Pathogenic	rs199422314	GRCh37	Chromosome 14, 24709836: 24709836
40	TINF2	NM_001099274.1(TINF2): c.850A> G (p.Thr284Ala)	single nucleotide variant	Pathogenic	rs199422314	GRCh38	Chromosome 14, 24240630: 24240630
41	TINF2	NM_001099274.1(TINF2): c.860T> C (p.Leu287Pro)	single nucleotide variant	Pathogenic	rs199422316	GRCh37	Chromosome 14, 24709826: 24709826
42	TINF2	NM_001099274.1(TINF2): c.860T> C (p.Leu287Pro)	single nucleotide variant	Pathogenic	rs199422316	GRCh38	Chromosome 14, 24240620: 24240620
43	TINF2	NM_001099274.1(TINF2): c.865_866delCCinsAG (p.Pro289Ser)	indel	Pathogenic	rs199422318	GRCh37	Chromosome 14, 24709820: 24709821
44	TINF2	NM_001099274.1(TINF2): c.865_866delCCinsAG (p.Pro289Ser)	indel	Pathogenic	rs199422318	GRCh38	Chromosome 14, 24240614: 24240615
45	TINF2	NM_001099274.1(TINF2): c.871A> G (p.Arg291Gly)	single nucleotide variant	Pathogenic	rs199422319	GRCh37	Chromosome 14, 24709815: 24709815
46	TINF2	NM_001099274.1(TINF2): c.871A> G (p.Arg291Gly)	single nucleotide variant	Pathogenic	rs199422319	GRCh38	Chromosome 14, 24240609: 24240609
47	TINF2	NM_001099274.1(TINF2): c.892delC (p.Gln298Argfs)	deletion	Pathogenic	rs199422320	GRCh37	Chromosome 14, 24709794: 24709794
48	TINF2	NM_001099274.1(TINF2): c.892delC (p.Gln298Argfs)	deletion	Pathogenic	rs199422320	GRCh38	Chromosome 14, 24240588: 24240588
49	TERT	NM_198253.2(TERT): c.1378_1380delCAG (p.Gln460del)	deletion	Benign	rs199422292	GRCh37	Chromosome 5, 1293621: 1293623
50	TERT	NM_198253.2(TERT): c.1378_1380delCAG (p.Gln460del)	deletion	Benign	rs199422292	GRCh38	Chromosome 5, 1293506: 1293508

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Expression for Dyskeratosis Congenita Autosomal Dominant

Search GEO for disease gene expression data for Dyskeratosis Congenita Autosomal Dominant.

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Pathways for Dyskeratosis Congenita Autosomal Dominant

Pathways related to Dyskeratosis Congenita Autosomal Dominant according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Chromosome Maintenance ⁶⁶ Show member pathways Deposition of new CENPA-containing nucleosomes at the centromere ⁶⁶ Nucleosome assembly ⁶⁶ Telomere Maintenance ⁶⁶	11.66	ACD TERT TINF2
2	Lung fibrosis ¹	10.96	RTEL1 TERT
3	Regulation of Telomerase ¹	10.62	ACD TERT TINF2
4	Telomere Extension by Telomerase ⁶⁴ Show member pathways XAV939 inhibits tankyrase, stabilizing AXIN ⁶⁶	10.58	TERT TINF2

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GO Terms for Dyskeratosis Congenita Autosomal Dominant

Cellular components related to Dyskeratosis Congenita Autosomal Dominant according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	chromosome	GO:0005694	9.58	ACD TERT TINF2
2	nuclear chromosome, telomeric region	GO:0000784	9.5	ACD TERT TINF2
3	ruffle	GO:0001726	9.43	CARMIL2 PARD6A
4	telomerase holoenzyme complex	GO:0005697	9.37	TERC TERT
5	shelterin complex	GO:0070187	9.26	ACD TINF2
6	telomerase catalytic core complex	GO:0000333	9.16	TERC TERT
7	nuclear telomere cap complex	GO:0000783	9.13	ACD TERT TINF2
8	chromosome, telomeric region	GO:0000781	9.02	ACD RTEL1 TERC TERT TINF2

Biological processes related to Dyskeratosis Congenita Autosomal Dominant according to GeneCards Suite gene sharing:

(show all 14)

#	Name	GO ID	Score	Top Affiliating Genes
1	DNA duplex unwinding	GO:0032508	9.54	RTEL1 RTEL1-TNFRSF6B
2	nucleobase-containing compound metabolic process	GO:0006139	9.52	RTEL1 RTEL1-TNFRSF6B
3	establishment or maintenance of cell polarity	GO:0007163	9.51	CARMIL2 PARD6A
4	DNA biosynthetic process	GO:0071897	9.49	TERC TERT
5	telomere capping	GO:0016233	9.48	ACD TINF2
6	telomere maintenance via telomerase	GO:0007004	9.46	TERC TERT
7	negative regulation of cellular senescence	GO:2000773	9.43	TERC TERT
8	negative regulation of telomere maintenance via telomerase	GO:0032211	9.4	ACD TINF2
9	regulation of double-strand break repair via homologous recombination	GO:0010569	9.37	RTEL1 RTEL1-TNFRSF6B
10	protein localization to chromosome, telomeric region	GO:0070198	9.32	ACD TINF2
11	establishment of protein localization to telomere	GO:0070200	9.26	ACD TERT
12	mitotic telomere maintenance via semi-conservative replication	GO:1902990	9.16	ACD RTEL1
13	telomere assembly	GO:0032202	8.96	ACD TINF2
14	telomere maintenance	GO:0000723	8.92	ACD RTEL1 RTEL1-TNFRSF6B TERT

Molecular functions related to Dyskeratosis Congenita Autosomal Dominant according to GeneCards Suite gene sharing:

(show all 12)

#	Name	GO ID	Score	Top Affiliating Genes
1	DNA binding	GO:0003677	9.91	ACD RTEL1 RTEL1-TNFRSF6B TERT TINF2
2	protein-containing complex binding	GO:0044877	9.65	ACD CARMIL2 TERC
3	iron-sulfur cluster binding	GO:0051536	9.49	RTEL1 RTEL1-TNFRSF6B
4	4 iron, 4 sulfur cluster binding	GO:0051539	9.46	RTEL1 RTEL1-TNFRSF6B
5	ATP-dependent DNA helicase activity	GO:0004003	9.43	RTEL1 RTEL1-TNFRSF6B
6	ATP-dependent helicase activity	GO:0008026	9.4	RTEL1 RTEL1-TNFRSF6B
7	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	GO:0016818	9.37	RTEL1 RTEL1-TNFRSF6B
8	RNA-directed DNA polymerase activity	GO:0003964	9.32	TERC TERT
9	telomerase activity	GO:0003720	9.26	TERC TERT
10	telomerase RNA reverse transcriptase activity	GO:0003721	9.16	TERC TERT
11	telomeric DNA binding	GO:0042162	9.13	ACD TERT TINF2
12	DNA polymerase binding	GO:0070182	8.8	ACD RTEL1 TERC

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Dyskeratosis Congenita Autosomal Dominant (DKCA)

Aliases & Classifications for Dyskeratosis Congenita Autosomal Dominant

MalaCards integrated aliases for Dyskeratosis Congenita Autosomal Dominant:

Classifications:

External Ids:

Summaries for Dyskeratosis Congenita Autosomal Dominant

Related Diseases for Dyskeratosis Congenita Autosomal Dominant

Diseases in the Dyskeratosis Congenita family:

Diseases related to Dyskeratosis Congenita Autosomal Dominant via text searches within MalaCards or GeneCards Suite gene sharing:

Graphical network of the top 20 diseases related to Dyskeratosis Congenita Autosomal Dominant:

Symptoms & Phenotypes for Dyskeratosis Congenita Autosomal Dominant

Drugs & Therapeutics for Dyskeratosis Congenita Autosomal Dominant

Genetic Tests for Dyskeratosis Congenita Autosomal Dominant

Genetic tests related to Dyskeratosis Congenita Autosomal Dominant:

Anatomical Context for Dyskeratosis Congenita Autosomal Dominant

MalaCards organs/tissues related to Dyskeratosis Congenita Autosomal Dominant:

Publications for Dyskeratosis Congenita Autosomal Dominant

Articles related to Dyskeratosis Congenita Autosomal Dominant:

Genes for Dyskeratosis Congenita Autosomal Dominant

Genes related to Dyskeratosis Congenita Autosomal Dominant (3 elite genes):

Variations for Dyskeratosis Congenita Autosomal Dominant

ClinVar genetic disease variations for Dyskeratosis Congenita Autosomal Dominant:

Expression for Dyskeratosis Congenita Autosomal Dominant

Pathways for Dyskeratosis Congenita Autosomal Dominant

Pathways related to Dyskeratosis Congenita Autosomal Dominant according to GeneCards Suite gene sharing:

GO Terms for Dyskeratosis Congenita Autosomal Dominant

Cellular components related to Dyskeratosis Congenita Autosomal Dominant according to GeneCards Suite gene sharing:

Biological processes related to Dyskeratosis Congenita Autosomal Dominant according to GeneCards Suite gene sharing:

Molecular functions related to Dyskeratosis Congenita Autosomal Dominant according to GeneCards Suite gene sharing:

Sources for Dyskeratosis Congenita Autosomal Dominant