MCID: DYS001
MIFTS: 33

Dyskinetic Cerebral Palsy

Categories: Neuronal diseases

Aliases & Classifications for Dyskinetic Cerebral Palsy

MalaCards integrated aliases for Dyskinetic Cerebral Palsy:

Name: Dyskinetic Cerebral Palsy 12 15
Athetoid Dyskinetic Cerebral Palsy 12
Athetoid Cerebral Palsy 73

Classifications:



External Ids:

Disease Ontology 12 DOID:0050672
ICD10 33 G80.3
UMLS 73 C0270742

Summaries for Dyskinetic Cerebral Palsy

Disease Ontology : 12 A cerebral palsy that is caused by damage to the extrapyramidal motor system and/or pyramidal tract and to the basal ganglia, which results in mixed muscle tone (hypertonia and hypotonia). The individuals have trouble holding themselves in an upright, steady position for sitting or walking, and often show involuntary motions.

MalaCards based summary : Dyskinetic Cerebral Palsy, also known as athetoid dyskinetic cerebral palsy, is related to cerebral palsy and cerebral palsy athetoid, and has symptoms including bradykinesia and abnormality of extrapyramidal motor function. An important gene associated with Dyskinetic Cerebral Palsy is NKX2-1 (NK2 Homeobox 1). Affiliated tissues include brain, eye and globus pallidus, and related phenotypes are homeostasis/metabolism and endocrine/exocrine gland

Related Diseases for Dyskinetic Cerebral Palsy

Graphical network of the top 20 diseases related to Dyskinetic Cerebral Palsy:



Diseases related to Dyskinetic Cerebral Palsy

Symptoms & Phenotypes for Dyskinetic Cerebral Palsy

UMLS symptoms related to Dyskinetic Cerebral Palsy:


bradykinesia, abnormality of extrapyramidal motor function

MGI Mouse Phenotypes related to Dyskinetic Cerebral Palsy:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.93 NPHS1 PNKD ADCY5 PTS AFP ATM
2 endocrine/exocrine gland MP:0005379 9.8 NKX2-1 AFP PTS ATM TRIP13 CYP27A1
3 mortality/aging MP:0010768 9.65 NPHS1 AFP PTS ATAD3A SIX3 ATM
4 nervous system MP:0003631 9.28 NPHS1 PNKD PTS SIX3 ATM CYP27A1

Drugs & Therapeutics for Dyskinetic Cerebral Palsy

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Effect of DBS on Quality of Life in Dyskinetic Cerebral Palsy Unknown status NCT02097693
2 Efficacy of Axial Stability on Improving Gait and Balance Performance in Children With Dyskinetic Cerebral Palsy Recruiting NCT03037697 Not Applicable

Search NIH Clinical Center for Dyskinetic Cerebral Palsy

Genetic Tests for Dyskinetic Cerebral Palsy

Anatomical Context for Dyskinetic Cerebral Palsy

MalaCards organs/tissues related to Dyskinetic Cerebral Palsy:

41
Brain, Eye, Globus Pallidus, Testes, Bone

Publications for Dyskinetic Cerebral Palsy

Articles related to Dyskinetic Cerebral Palsy:

(show top 50) (show all 56)
# Title Authors Year
1
Clinical characteristics and functional status of children with different subtypes of dyskinetic cerebral palsy. ( 29794768 )
2018
2
<i>TSEN54</i> Gene-Related Pontocerebellar Hypoplasia Type 2 Could Mimic Dyskinetic Cerebral Palsy with Severe Psychomotor Retardation. ( 29410950 )
2018
3
Botulinum Toxin Type A Injection for Cervical Dystonia in Adults with Dyskinetic Cerebral Palsy. ( 29772695 )
2018
4
Cognitive functioning in dyskinetic cerebral palsy: Its relation to motor function, communication and epilepsy. ( 29108712 )
2018
5
A case of new PCDH12 gene variants presented as dyskinetic cerebral palsy with epilepsy. ( 29556033 )
2018
6
Intrathecal baclofen in dyskinetic cerebral palsy: effects on function and activity. ( 29148568 )
2018
7
Oropharyngeal dysphagia in adults with dyskinetic cerebral palsy and cervical dystonia: a preliminary study. ( 29958905 )
2018
8
A commentary on a case of new PCDH12 gene variants presented as dyskinetic cerebral palsy with epilepsy. ( 29904113 )
2018
9
Whole-brain structural connectivity in dyskinetic cerebral palsy and its association with motor and cognitive function. ( 28608616 )
2017
10
Bilateral globus pallidus internus deep brain stimulation for dyskinetic cerebral palsy supports success of cochlear implantation in a 5-year old ex-24A week preterm twin with absent cerebellar hemispheres. ( 28017556 )
2017
11
White matter integrity in dyskinetic cerebral palsy: Relationship with intelligence quotient and executive function. ( 28702354 )
2017
12
Functional outcomes in children and young people with dyskinetic cerebral palsy. ( 28272743 )
2017
13
Medical treatment of dyskinetic cerebral palsy: translation into practice. ( 28892137 )
2017
14
Efficacy of oral pharmacological treatments in dyskinetic cerebral palsy: a systematic review. ( 28872668 )
2017
15
Clinical presentation and management of dyskinetic cerebral palsy. ( 28816119 )
2017
16
A systematic review of scales to measure dystonia and choreoathetosis in children with dyskinetic cerebral palsy. ( 28485494 )
2017
17
Stable cognitive functioning with improved perceptual reasoning in children with dyskinetic cerebral palsy and other secondary dystonias after deep brain stimulation. ( 27836441 )
2017
18
Towards a comprehensive profile of dyskinetic cerebral palsy. ( 28295237 )
2017
19
Localization of Basal Ganglia and Thalamic Damage in Dyskinetic Cerebral Palsy. ( 26706479 )
2016
20
Proxy-reported quality of life in adolescents and adults with dyskinetic cerebral palsy is associated with executive functions and cortical thickness. ( 27766516 )
2016
21
The relationship of dystonia and choreoathetosis with activity, participation and quality of life in children and youth with dyskinetic cerebral palsy. ( 27707657 )
2016
22
Correction: Neuroradiological and Neurophysiological Characteristics of Patients With Dyskinetic Cerebral Palsy. ( 26361607 )
2015
23
The quest for patterns in dyskinetic cerebral palsy. ( 26257200 )
2015
24
Clinical patterns of dystonia and choreoathetosis in participants with dyskinetic cerebral palsy. ( 26173923 )
2015
25
Young Adults with Dyskinetic Cerebral Palsy Improve Subjectively on Pallidal Stimulation, but not in Formal Dystonia, Gait, Speech and Swallowing Testing. ( 25322688 )
2014
26
Responsiveness of the MD-Childhood Rating Scale in dyskinetic cerebral palsy patients undergoing anticholinergic treatment. ( 25022341 )
2014
27
Adults with spastic cerebral palsy have lower bone mass than those with dyskinetic cerebral palsy. ( 25316282 )
2014
28
Neuroradiological and neurophysiological characteristics of patients with dyskinetic cerebral palsy. ( 24855613 )
2014
29
Effects of deep brain stimulation in dyskinetic cerebral palsy: a meta-analysis. ( 23408442 )
2013
30
NKX2-1 mutation in a family diagnosed with ataxic dyskinetic cerebral palsy. ( 23911641 )
2013
31
Three-dimensional analysis of performance of an upper limb functional task among adults with dyskinetic cerebral palsy. ( 24373786 )
2013
32
Septo-optic dysplasia-plus and dyskinetic cerebral palsy in a child. ( 21533562 )
2012
33
The challenge of dyskinetic cerebral palsy. ( 22428171 )
2012
34
The Dyskinesia Impairment Scale: a new instrument to measure dystonia and choreoathetosis in dyskinetic cerebral palsy. ( 22428172 )
2012
35
Os odontoideum as a rare but possible complication in children with dyskinetic cerebral palsy: a clinical and neuroradiologic study. ( 21616925 )
2011
36
Dyskinetic cerebral palsy in Europe: trends in prevalence and severity, on behalf of the SCPE Collaboration. ( 19933598 )
2009
37
Levetiracetam therapy for treatment of choreoathetosis in dyskinetic cerebral palsy. ( 19018837 )
2009
38
Is levetiracetam a treatment option for dyskinetic cerebral palsy? ( 19563584 )
2009
39
Dyskinetic cerebral palsy in Europe: trends in prevalence and severity. ( 19465585 )
2009
40
Dyskinetic cerebral palsy: prevalence and neuroimaging. ( 17376131 )
2007
41
Dyskinetic cerebral palsy: a population-based study of children born between 1991 and 1998. ( 17376133 )
2007
42
Arm trajectories in dyskinetic cerebral palsy have increased random variability. ( 16970842 )
2006
43
Urinary retention due to clonazepam in a child with dyskinetic cerebral palsy. ( 14980361 )
2004
44
The early markers for later dyskinetic cerebral palsy are different from those for spastic cerebral palsy. ( 12075487 )
2002
45
Very high serum creatine kinase level in a child with dyskinetic cerebral palsy. ( 12142071 )
2002
46
Visual impairment due to a dyskinetic eye movement disorder in children with dyskinetic cerebral palsy. ( 12033724 )
2002
47
Visual impairment due to a dyskinetic eye movement disorder in children with dyskinetic cerebral palsy. ( 11221897 )
2001
48
Reduced accommodative function in dyskinetic cerebral palsy: a novel management strategy. ( 11085300 )
2000
49
Dyskinetic cerebral palsy: a clinical and genetic study. ( 8870609 )
1996
50
A case of dyskinetic cerebral palsy resembling post-anoxic action myoclonus. ( 7573763 )
1995

Variations for Dyskinetic Cerebral Palsy

Expression for Dyskinetic Cerebral Palsy

Search GEO for disease gene expression data for Dyskinetic Cerebral Palsy.

Pathways for Dyskinetic Cerebral Palsy

GO Terms for Dyskinetic Cerebral Palsy

Biological processes related to Dyskinetic Cerebral Palsy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 reciprocal meiotic recombination GO:0007131 9.4 ATM TRIP13
2 pituitary gland development GO:0021983 9.37 NKX2-1 SIX3
3 telencephalon development GO:0021537 9.32 NKX2-1 SIX3
4 mitotic spindle assembly checkpoint GO:0007094 9.26 ATM TRIP13
5 cerebral cortex neuron differentiation GO:0021895 9.16 HPRT1 NKX2-1
6 locomotory behavior GO:0007626 9.13 ADCY5 HPRT1 NKX2-1
7 forebrain dorsal/ventral pattern formation GO:0021798 8.62 NKX2-1 SIX3

Sources for Dyskinetic Cerebral Palsy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....