DYX1
MCID: DYS121
MIFTS: 19

Dyslexia 1 (DYX1)

Categories: Genetic diseases, Mental diseases

Aliases & Classifications for Dyslexia 1

MalaCards integrated aliases for Dyslexia 1:

Name: Dyslexia 1 57 75 29 6
Dyslexia, Susceptibility to, 1 57 13
Dyx1 57 75
Specific Reading Disability Type 1 75
Reading Disability, Specific, 1 57
Word-Blindness, Congenital 57
Congenital Word-Blindness 75
Dyslexia, Type 1 40
Dyslexia 4 75
Dyslexia 7 75
Dyx4 75
Dyx7 75

Characteristics:

OMIM:

57
Inheritance:
autosomal dominant


HPO:

32
dyslexia 1:
Inheritance autosomal dominant inheritance


Classifications:



External Ids:

OMIM 57 127700

Summaries for Dyslexia 1

OMIM : 57 Dyslexia is a disorder manifested by difficulty learning to read despite conventional instruction, adequate intelligence, and sociocultural opportunity. It is among the most common neurodevelopmental disorders, with a prevalence of 5 to 12%. Although there is evidence for familial clustering and heritability, the disorder is considered a complex multifactorial trait (Schumacher et al., 2007). (127700)

MalaCards based summary : Dyslexia 1, also known as dyslexia, susceptibility to, 1, is related to dyslexia and alexia. An important gene associated with Dyslexia 1 is DNAAF4 (Dynein Axonemal Assembly Factor 4). Related phenotypes are neurological speech impairment and dyslexia

UniProtKB/Swiss-Prot : 75 Dyslexia 1: A relatively common, complex cognitive disorder characterized by an impairment of reading performance despite adequate motivational, educational and intellectual opportunities. It is a multifactorial trait, with evidence for familial clustering and heritability.

Related Diseases for Dyslexia 1

Diseases in the Dyslexia family:

Dyslexia 1 Dyslexia 9
Dyslexia 2 Dyslexia 3
Dyslexia 6 Dyslexia 5
Dyslexia 8

Diseases related to Dyslexia 1 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 dyslexia 28.1 DNAAF4 DNAAF4-CCPG1
2 alexia 9.8

Symptoms & Phenotypes for Dyslexia 1

Symptoms via clinical synopsis from OMIM:

57
Neuro:
dyslexia
speech defects


Clinical features from OMIM:

127700

Human phenotypes related to Dyslexia 1:

32
# Description HPO Frequency HPO Source Accession
1 neurological speech impairment 32 HP:0002167
2 dyslexia 32 HP:0010522

Drugs & Therapeutics for Dyslexia 1

Search Clinical Trials , NIH Clinical Center for Dyslexia 1

Genetic Tests for Dyslexia 1

Genetic tests related to Dyslexia 1:

# Genetic test Affiliating Genes
1 Dyslexia 1 29 DNAAF4

Anatomical Context for Dyslexia 1

Publications for Dyslexia 1

Articles related to Dyslexia 1:

# Title Authors Year
1
The effect of contrast on reading speed in dyslexia(1) ( 11024448 )
2000

Variations for Dyslexia 1

Expression for Dyslexia 1

Search GEO for disease gene expression data for Dyslexia 1.

Pathways for Dyslexia 1

GO Terms for Dyslexia 1

Sources for Dyslexia 1

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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