MCID: DYS120
MIFTS: 19

Dyslexia 2

Categories: Genetic diseases, Mental diseases

Aliases & Classifications for Dyslexia 2

MalaCards integrated aliases for Dyslexia 2:

Name: Dyslexia 2 57 75 29
Dyslexia, Susceptibility to, 2 57 13
Dyx2 57 75
Specific Reading Disability Type 2 75
Reading Disability, Specific, 2 57
Dyslexia, Type 2 40

Characteristics:

OMIM:

57
Inheritance:
autosomal dominant quantitative trait locus (qtl) 6p21.3


Classifications:



External Ids:

OMIM 57 600202
MedGen 42 C1838436
SNOMED-CT via HPO 69 52824009 59770006 9236007

Summaries for Dyslexia 2

UniProtKB/Swiss-Prot : 75 Dyslexia 2: A relatively common, complex cognitive disorder characterized by an impairment of reading performance despite adequate motivational, educational and intellectual opportunities. It is a multifactorial trait, with evidence for familial clustering and heritability.

MalaCards based summary : Dyslexia 2, also known as dyslexia, susceptibility to, 2, is related to dyslexia and reading disorder. An important gene associated with Dyslexia 2 is KIAA0319 (KIAA0319). Related phenotype is dyslexia.

Description from OMIM: 600202

Related Diseases for Dyslexia 2

Diseases in the Dyslexia family:

Dyslexia 1 Dyslexia 9
Dyslexia 2 Dyslexia 3
Dyslexia 6 Dyslexia 5
Dyslexia 8

Diseases related to Dyslexia 2 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 dyslexia 30.3 DCDC2 DYX2 KIAA0319
2 reading disorder 9.2 DCDC2 KIAA0319
3 specific developmental disorder 9.1 DCDC2 KIAA0319
4 attention deficit-hyperactivity disorder 8.9 DCDC2 KIAA0319

Symptoms & Phenotypes for Dyslexia 2

Symptoms via clinical synopsis from OMIM:

57
Neuro:
dyslexia
reading disability


Clinical features from OMIM:

600202

Human phenotypes related to Dyslexia 2:

32
# Description HPO Frequency HPO Source Accession
1 dyslexia 32 HP:0010522

Drugs & Therapeutics for Dyslexia 2

Search Clinical Trials , NIH Clinical Center for Dyslexia 2

Genetic Tests for Dyslexia 2

Genetic tests related to Dyslexia 2:

# Genetic test Affiliating Genes
1 Dyslexia 2 29 KIAA0319

Anatomical Context for Dyslexia 2

Publications for Dyslexia 2

Variations for Dyslexia 2

Expression for Dyslexia 2

Search GEO for disease gene expression data for Dyslexia 2.

Pathways for Dyslexia 2

GO Terms for Dyslexia 2

Biological processes related to Dyslexia 2 according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nervous system development GO:0007399 8.96 DCDC2 KIAA0319
2 neuron migration GO:0001764 8.62 DCDC2 KIAA0319

Sources for Dyslexia 2

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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