DYX8
MCID: DYS125
MIFTS: 16

Dyslexia 8 (DYX8)

Categories: Genetic diseases, Mental diseases, Neuronal diseases

Aliases & Classifications for Dyslexia 8

MalaCards integrated aliases for Dyslexia 8:

Name: Dyslexia 8 56
Dyslexia, Susceptibility to, 8 56 13
Dyx8 56

Characteristics:

OMIM:

56
Inheritance:
autosomal dominant
multifactorial



Classifications:



External Ids:

OMIM 56 608995
MedGen 41 C1837009

Summaries for Dyslexia 8

MalaCards based summary : Dyslexia 8, also known as dyslexia, susceptibility to, 8, is related to dyslexia and reading disorder. An important gene associated with Dyslexia 8 is DYX8 (Dyslexia Susceptibility 8). Related phenotype is dyslexia.

More information from OMIM: 608995

Related Diseases for Dyslexia 8

Diseases in the Dyslexia family:

Dyslexia 1 Dyslexia 9
Dyslexia 2 Dyslexia 3
Dyslexia 6 Dyslexia 5
Dyslexia 8

Diseases related to Dyslexia 8 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 dyslexia 11.8
2 reading disorder 10.2

Symptoms & Phenotypes for Dyslexia 8

Human phenotypes related to Dyslexia 8:

31
# Description HPO Frequency HPO Source Accession
1 dyslexia 31 HP:0010522

Symptoms via clinical synopsis from OMIM:

56
Neurologic Central Nervous System:
dyslexia
difficulty in spelling
difficulty in phonologic coding
decreased rapid automatized naming (ran) speed

Clinical features from OMIM:

608995

Drugs & Therapeutics for Dyslexia 8

Search Clinical Trials , NIH Clinical Center for Dyslexia 8

Genetic Tests for Dyslexia 8

Anatomical Context for Dyslexia 8

Publications for Dyslexia 8

Articles related to Dyslexia 8:

(show all 16)
# Title Authors PMID Year
1
Confirmation of a dyslexia susceptibility locus on chromosome 1p34-p36 in a set of 100 Canadian families. 56 61
15108193 2004
2
Confirmation of dyslexia susceptibility loci on chromosomes 1p and 2p, but not 6p in a Dutch sib-pair collection. 56
17886254 2008
3
Linkage studies suggest a possible locus for developmental dyslexia on chromosome 1p. 56
11424982 2001
4
Suggestive linkage of developmental dyslexia to chromosome 1p34-p36. 56
8101276 1993
5
Reading in English as a Foreign Language by Spanish Children With Dyslexia. 61
32116890 2020
6
Embryonic disruption of the candidate dyslexia susceptibility gene homolog Kiaa0319-like results in neuronal migration disorders. 61
23831424 2013
7
Dyslexia-associated kiaa0319-like protein interacts with axon guidance receptor nogo receptor 1. 61
20697954 2011
8
A cohort of balanced reciprocal translocations associated with dyslexia: identification of two putative candidate genes at DYX1. 61
20798984 2011
9
The genetics of reading disability. 61
19302769 2009
10
Linkage to chromosome 1p36 for attention-deficit/hyperactivity disorder traits in school and home settings. 61
18439570 2008
11
Abnormal fMRI Connectivity in Children with Dyslexia During a Phoneme Task: Before But Not After Treatment . 61
19079567 2008
12
The KIAA0319-like (KIAA0319L) gene on chromosome 1p34 as a candidate for reading disabilities. 61
19085271 2008
13
Further evidence of pleiotropy influencing speech and language: analysis of the DYX8 region. 61
17230025 2007
14
Neural deficits in children with dyslexia ameliorated by behavioral remediation: evidence from functional MRI. 61
12604786 2003
15
Comments on 'The dyslexia ecosystem': a reply to Nicolson. 61
12455852 2002
16
Effects of reading and writing on cerebral laterality in good readers and children with dyslexia. 61
1765731 1991

Variations for Dyslexia 8

Expression for Dyslexia 8

Search GEO for disease gene expression data for Dyslexia 8.

Pathways for Dyslexia 8

GO Terms for Dyslexia 8

Sources for Dyslexia 8

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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