Drugs for Dysplastic Nevus Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):
(show all 30)
# |
|
Name |
Status |
Phase |
Clinical Trials |
Cas Number |
PubChem Id |
1 |
|
Tretinoin |
Approved, Investigational, Nutraceutical |
Phase 2 |
|
302-79-4 |
444795 5538 |
Synonyms:
(2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoate
(all-e)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoate
(all-e)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid
(all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid
.beta.-Retinoic acid
[3H]Retinoic acid
13497-05-7 (hydrochloride salt)
15-Apo-beta-caroten-15-oic acid
187175-63-9
1n4h
3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid
3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexene-1-yl)-2,4,6,8-nonatetraenoate (ecl)
3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexene-1-yl)-2,4,6,8-nonatetraenoic acid (ecl)
3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexene-1-yl)-2,4,6,8-nonatetraenoic acid (ECL)
302-79-4
5300-03-8
56573-65-0
7005-78-9
9(Z)-Retinoic acid
9-cis-RA
A-Acido (Argentina)
Aberel
Aberela
Aberela [Norway]
AC1L9GWO
AC1Q1J2J
AC-6824
Accutane Roche
Acid A Vit (Belgium, Netherlands)
Acid, all-trans-retinoic
Acid, all-trans-Retinoic
Acid, beta-all-trans-retinoic
Acid, beta-all-trans-Retinoic
Acid, retinoic
Acid, Retinoic
Acid, trans-retinoic
Acid, trans-Retinoic
Acid, vitamin a
Acid, Vitamin A
Acide retinoique
Acide retinoique (French) (DSL)
Acnavit
Acnavit [Denmark]
AGN 100335
AGN 192013
Airol
Aknefug
Aknoten
AKOS000280845
Alitretinoin
all trans Retinoic acid
All Trans Retinoic Acid
all trans-Retinoic acid
All Trans-Retinoic Acid
all-(e)-Retinoate
all-(e)-Retinoic acid
all-(E)-Retinoic acid
All-trans Retinoic Acid
all-trans-beta-Retinoate
all-trans-beta-Retinoic acid
all-trans-b-Retinoate
all-trans-b-Retinoic acid
all-trans-Retinoic acid
Alltrans-retinoic acid
all-trans-Tretinoin
all-trans-Vitamin a acid
all-trans-Vitamin A acid
all-trans-Vitamin a1 acid
all-trans-Vitamin A1 acid
all-trans-β-retinoate
all-trans-β-retinoic acid
ALRT 1057
Amnesteem
ATRA
AT-RA
Atragen
Atra-IV
Atralin
Avita (TN)
Avita Gel
A-Vitaminsyre
A-Vitaminsyre [Denmark]
Avitoin
Avitoin [Norway]
BAL4079
beta all trans Retinoic acid
beta all trans Retinoic Acid
beta-all-trans-Retinoic acid
beta-Ra
beta-Retinoate
beta-Retinoic acid
beta-Retinoic Acid
Betarretin
BIDD:GT0483
BIDD:PXR0081
BML2-E05
bmse000562
BPBio1_000082
b-Retinoate
b-Retinoic acid
BRN 2057223
BSPBio_000074
BSPBio_001500
C00777
CCRIS 3294
CCRIS 7098
CHEBI:15367
CHEMBL38
CID444795
Claravis
Cordes vas
Cordes VAS [Germany]
CPD000058245
D00094
D014212
DB00523
DB00755
DB00982
Dermairol
Effederm
Effederm [France]
EINECS 206-129-0
Epi-aberel
EU-0101061
Eudyna
HMS1361K22
HMS1568D16
HMS1791K22
HMS1921D14
HMS1989K22
HMS2089D20
HMS2092N11
HMS502N05
HSDB 2169
|
HSDB 7186
I04-0008
I14-2351
IDI1_000903
IDI1_033970
Isotretinoin Retinoic acid
L000833
LGD 100057
LMPR01090019
Lopac0_001061
LS-1154
Lsotretinoin
MLS000028588
MLS001076515
MLS002207234
MLS002222211
MolPort-000-883-857
NCGC00017280-06
NCGC00017280-17
NCGC00021808-04
NCGC00021808-05
NCGC00021808-06
NCGC00021808-07
NCGC00021808-09
NCGC00021808-14
NCGC00021808-15
nchembio.154-comp2
Nexret
NSC 122758
NSC122758
NSC-122758
Panretin Gel
Panretyn
PDT-002-002
Potassium salt, tretinoin
Potassium Salt, Tretinoin
Prestwick_424
Prestwick2_000257
Prestwick3_000257
R 2625
R0064
R2625_SIGMA
REA
Renova
Renova (TN)
Retacnyl
Retin a
Retin A
Retin A (TN)
Retin-a
Retin-A
Retin-A Micro
Retinoate
Retinoic acid
RETINOIC ACID, ALL TRANS
Retinoic acid, all-trans- (8CI)
Retinova
Retionic acid
Retionic Acid
Retisol-a
Retisol-A
ro 1-5488
Ro 1-5488
S1653_Selleck
Salt, tretinoin potassium
Salt, Tretinoin Potassium
Salt, tretinoin sodium
Salt, Tretinoin Sodium
Salt, tretinoin zinc
Salt, Tretinoin Zinc
SAM002264647
SMR000058245
Sodium salt, tretinoin
Sodium Salt, Tretinoin
Solage
Sotret
SPECTRUM1502016
Spectrum5_001746
Spectrum5_001933
SR-01000000239
SR-01000000239-14
ST057075
Stieva-a
Stieva-A
Stieva-a Forte
trans Retinoic acid
trans Retinoic Acid
trans-Retinoate
trans-Retinoic acid
Tretin m
Tretin M
tretinoin
Tretinoin
Tretinoin (JAN/USP/INN)
Tretinoin (TN)
Tretinoin [USAN:INN:BAN]
Tretinoin 0.1% cream or placebo
tretinoin liposome
Tretinoin potassium salt
Tretinoin Potassium Salt
Tretinoin sodium salt
Tretinoin Sodium Salt
Tretinoin zinc salt
Tretinoin Zinc Salt
Tretinoin/All-Trans Retinoic Acid
Tretinoina
Tretinoina [INN-Spanish]
Tretinoine
Trétinoïne
tretinoine (French) (EINECS)
Tretinoine [INN-French]
Tretinoino
Tretinoino [INN-Spanish]
Tretinoinum
Tretinoinum [INN-Latin]
TRETINON
Tri-Luma
UNII-1UA8E65KDZ
UNII-5688UTC01R
UPCMLD-DP097
Vesanoid
Vesanoid (TN)
Vesanoid, Airol, Renova, Atralin, Retin-A, Avita, Tretinoin
Vesnaroid
Vitamin a acid
Vitamin A acid
Vitinoin
WLN: L6UTJ A1 B1U1Y1 & U2U1Y1 & U1VQ C1 C1
WLN: L6UTJ A1 B1U1Y1&U2U1Y1&U1VQ C1 C1
Zinc salt, tretinoin
Zinc Salt, Tretinoin
β-retinoate
β-retinoic acid
|
|
2 |
|
Fenretinide |
Investigational |
Phase 2 |
|
65646-68-6 |
|
Synonyms:
4-HPR
4-hydroxy(phenyl)retinamide
4-hydroxyphenyl retinamide
Fenretinida
|
Fenretinide
Fenretinidum
N-(4-hydroxyphenyl)all-trans retinamide
|
|
3 |
|
Betulinic acid |
Investigational |
Phase 1, Phase 2 |
|
472-15-1 |
64971 |
Synonyms:
3-Epi-betulinic acid
beta-betulinic acid
Betulic acid
|
|
|
4 |
|
Dermatologic Agents |
|
Phase 2 |
|
|
|
5 |
|
Protective Agents |
|
Phase 2 |
|
|
|
6 |
|
Keratolytic Agents |
|
Phase 2 |
|
|
|
7 |
|
Hormone Antagonists |
|
Phase 1, Phase 2 |
|
|
|
8 |
|
Hormones |
|
Phase 1, Phase 2 |
|
|
|
9 |
|
Anti-HIV Agents |
|
Phase 1, Phase 2 |
|
|
|
10 |
|
Analgesics, Non-Narcotic |
|
Phase 1, Phase 2 |
|
|
|
11 |
|
Prostaglandin Antagonists |
|
Phase 1, Phase 2 |
|
|
|
12 |
|
Anti-Infective Agents |
|
Phase 1, Phase 2 |
|
|
|
13 |
|
Analgesics |
|
Phase 1, Phase 2 |
|
|
|
14 |
|
Anti-Inflammatory Agents |
|
Phase 1, Phase 2 |
|
|
|
15 |
|
Antiparasitic Agents |
|
Phase 1, Phase 2 |
|
|
|
16 |
|
Antiviral Agents |
|
Phase 1, Phase 2 |
|
|
|
17 |
|
Antirheumatic Agents |
|
Phase 1, Phase 2 |
|
|
|
18 |
|
Antiprotozoal Agents |
|
Phase 1, Phase 2 |
|
|
|
19 |
|
Antimalarials |
|
Phase 1, Phase 2 |
|
|
|
20 |
|
Anti-Retroviral Agents |
|
Phase 1, Phase 2 |
|
|
|
21 |
|
Anti-Inflammatory Agents, Non-Steroidal |
|
Phase 1, Phase 2 |
|
|
|
22 |
|
Pancrelipase |
Approved, Investigational |
|
|
53608-75-6 |
|
Synonyms:
lipase
Pancrealipase
Pancreatic extract pancrelipase
Pancreatic protease
|
Pancreatin
Pancreatinum
Pancrelipase (amylase
protease)
|
|
23 |
|
Secretin |
Approved |
|
|
108153-74-8 |
|
Synonyms:
108153-74-8
1393-25-5
67307-60-2 (citrate (salt))
9002-77-1
EINECS 215-733-3
Hormone of the duodenal mucosa that activates pancreatic secretion and lowers the blood sugar level
Human secretin
I06-1828
L-Histidyl-L-seryl-L-alpha-aspartylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-glutamyl-L-leucyl-L-seryl-L-arginyl-L-leucyl-L-arginyl-L-alpha-aspartyl-L-seryl-L-alanyl-L-arginyl-L-leucyl-L-glutaminyl-L-arginyl-L-leucyl-L-leucyl-L-glutaminylglycyl-L-leucyl-L-valinamide
L-Histidyl-L-seryl-L-alpha-aspartylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-glutamyl-L-leucyl-L-seryl-L-arginyl-L-leucyl-L-arginyl-L-alpha-glutamylglycyl-L-alanyl-L-arginyl-L-leucyl-L-glutaminyl-L-arginyl-L-leucyl-L-leucyl-L-glutaminylglycyl-L-leucyl-L-valinamide
LS-144747
RG 1068
SECREFLO
SecreFlow
Secrepan
Secretin
SECRETIN
Secretin (human)
|
Secretin (porcine)
Secretin [INN:BAN:DCF:JAN]
Secretin human
Secretin synthetic human
Secretina
Secretina [INN-Spanish]
Secretine
Secretine [INN-French]
SECRETIN-FERRING
Secretin-Kabi
Secretinum
Secretinum [INN-Latin]
Secretolin
Synthetic human secretin
UNII-88C55N56UU
UNII-A0426J905J
Vitrum
|
|
24 |
|
Formaldehyde |
Approved, Vet_approved |
|
|
50-00-0 |
712 |
Synonyms:
Aldeide formica
Fannoform
Formaldehído
Formaldehyd
Formaldehyde
Formaldehyde solution
Formalin
FORMALIN
Formalina
Formaline
Formalith
|
Formic aldehyde
Formol
Methaldehyde
Methanal
Methyl aldehyde
Methylene glycol
Methylene oxide
Oxomethane
Oxomethylene
Oxymethylene
Paraform
|
|
25 |
|
Sulforaphane |
Investigational |
Early Phase 1 |
|
142825-10-3, 4478-93-7 |
5350 |
Synonyms:
(-)-sulforaphane
(R)-sulforaphane
(R)-Sulphoraphane
1-isothiocyanato-4-Methylsulphinylbutane
4-methylsulfinylbutyl isothiocyanate
|
4-Methylsulphinylbutyl glucosinolate
Methylsulfoxybutylisothiocyanate
Sulforafan
Sulphorafan
Sulphoraphane
|
|
26 |
|
Sulforafan |
|
Early Phase 1 |
|
|
|
27 |
|
pancreatin |
|
|
|
|
|
28 |
|
Gastrointestinal Agents |
|
|
|
|
|
29 |
|
Anesthetics |
|
|
|
|
|
30 |
|
Serine |
Investigational, Nutraceutical |
|
|
56-45-1 |
5951 |
Synonyms:
(-)-Serine
(2S)-2-amino-3-Hydroxypropanoate
(2S)-2-amino-3-Hydroxypropanoic acid
(S)-(-)-Serine
(S)-2-amino-3-Hydroxypropanoate
(S)-2-amino-3-Hydroxy-propanoate
(S)-2-amino-3-Hydroxypropanoic acid
(S)-2-amino-3-Hydroxy-propanoic acid
(S)-2-Amino-3-hydroxypropanoic acid
(S)-a-amino-b-Hydroxypropionate
(S)-a-amino-b-Hydroxypropionic acid
(S)-alpha-amino-beta-Hydroxypropionate
(S)-alpha-amino-beta-Hydroxypropionic acid
(S)-b-amino-3-Hydroxypropionate
(S)-b-amino-3-Hydroxypropionic acid
(S)-beta-amino-3-Hydroxypropionate
(S)-beta-amino-3-Hydroxypropionic acid
(S)-Serine
(S)-α-amino-β-hydroxypropionate
(S)-α-amino-β-hydroxypropionic acid
2-amino-3-Hydroxypropanoate
2-amino-3-Hydroxypropanoic acid
3-Hydroxy-L-alanine
|
alpha-Amino-beta-hydroxypropionic acid
beta-Hydroxyalanine
beta-Hydroxy-L-alanine
b-Hydroxyalanine
b-Hydroxy-L-alanine
L Serine
L-(-)-Serine
L-2-amino-3-Hydroxypropionate
L-2-amino-3-Hydroxypropionic acid
L-3-Hydroxy-2-aminopropionate
L-3-Hydroxy-2-aminopropionic acid
L-3-Hydroxy-alanine
L-Ser
L-Serin
L-Serine
S
Ser
Serina
Serine
SERINE
Serinum
β-hydroxyalanine
β-hydroxy-L-alanine
|
|
Interventional clinical trials:
(show all 19)
# |
Name |
Status |
NCT ID |
Phase |
Drugs |
1 |
A Phase II Double-Blind Study of Topical Tretinoin With or Without Oral 4-HPR (Fenretinide) in Patients With the Dysplastic Nevus Syndrome |
Completed |
NCT00003601 |
Phase 2 |
fenretinide;tretinoin |
2 |
Phase I/II Evaluation of Topical Application of 20% Betulinic Acid Ointment in the Treatment of Dysplastic Nevi With Moderate to Severe Dysplasia |
Suspended |
NCT00346502 |
Phase 1, Phase 2 |
20% betulinic acid ointment;BA |
3 |
Identification of the Genetic Mutation Responsible for Segmental Dysplastic Nevi |
Unknown status |
NCT00955578 |
|
|
4 |
Dermoscopy Evaluation of Pigmented Skin Lesions by a Neuronal Network Clinical Decision Support: an Open Prospective Non Interventional Study |
Unknown status |
NCT03362138 |
|
|
5 |
Using High Resolution Function Imaging To Detect Melanoma and Dysplastic Nevi |
Completed |
NCT01118832 |
|
|
6 |
Potential Research Study Participant Registry |
Completed |
NCT00710489 |
|
|
7 |
Prospective Study of 2 mm Margins for the Biopsy of Dysplastic Nevi |
Completed |
NCT03094273 |
|
|
8 |
A Pilot Study Evaluation of Sulforaphane in Atypical Nevi--Precursor Lesions: Assessment of STAT1 and STAT3 Risk Markers of Melanoma |
Completed |
NCT01568996 |
Early Phase 1 |
broccoli sprout extract - sulforaphane (BSE-SFN);broccoli sprout extract - sulforaphane (BSE-SFN);broccoli sprout extract - sulforaphane (BSE-SFN) |
9 |
Observational Study to Analyze the Outcomes of Subjects Who - Based Upon Their Sufficiently Elevated Risk for the Development of Pancreatic Adenocarcinoma- Elect to Undergo Early Detection Testing |
Recruiting |
NCT02206360 |
|
|
10 |
The Cancer of the Pancreas Screening-5 CAPS5)Study |
Recruiting |
NCT02000089 |
|
Human synthetic secretin |
11 |
Pancreas Disease and High Risk Registry |
Recruiting |
NCT02775461 |
|
|
12 |
Italian Registry of Families At Risk of Pancreatic Cancer |
Recruiting |
NCT04095195 |
|
|
13 |
An Online Intervention for Skin Self-Checks Among Individuals at Increased Risk for Melanoma |
Recruiting |
NCT03725449 |
|
|
14 |
A Multicenter, Ambispective, Low-interventional Clinical Study Evaluating Molecular Genetic Markers for Non-invasive Differential Diagnosis of Benign and Malignant Pigmented Skin and Mucosal Neoplasms |
Recruiting |
NCT04353050 |
|
|
15 |
A Prospective, Multi-center Investigational Study of IMMrayâ„¢ PanCan-d Diagnostic Assay for Early Detection of Pancreatic Ductal Adenocarcinoma in High-risk Populations |
Recruiting |
NCT03693378 |
|
|
16 |
Family Study of Melanoma in Italy |
Recruiting |
NCT00339222 |
|
|
17 |
Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of Melanoma |
Recruiting |
NCT00040352 |
|
|
18 |
Skin Lesion Detection With Novel Total Body Digital Photography Smartphone Application |
Active, not recruiting |
NCT02740257 |
|
|
19 |
Pancreatic Cancer Screening of High-Risk Individuals in Arkansas |
Withdrawn |
NCT02309632 |
|
|
|