MCID: ERL005
MIFTS: 22

Early Invasive Cervical Adenocarcinoma

Categories: Cancer diseases, Rare diseases, Reproductive diseases
Data Licensing
For inquiries, contact:

Aliases & Classifications for Early Invasive Cervical Adenocarcinoma

MalaCards integrated aliases for Early Invasive Cervical Adenocarcinoma:

Name: Early Invasive Cervical Adenocarcinoma 11 14 71

Classifications:



External Ids:

Disease Ontology 11 DOID:8307
NCIt 49 C36096
UMLS 71 C1333369

Summaries for Early Invasive Cervical Adenocarcinoma

Disease Ontology: 11 A cervical adenocarcinoma that is characterized by tumor cells that are identical to those in adenocarcinoma in situ (ACIS) and mcroscopic findings that suggest invasion.

MalaCards based summary: Early Invasive Cervical Adenocarcinoma is related to cervical adenocarcinoma and adenocarcinoma. An important gene associated with Early Invasive Cervical Adenocarcinoma is INSM1 (INSM Transcriptional Repressor 1), and among its related pathways/superpathways are Intrinsic Pathway for Apoptosis and Senescence and autophagy in cancer. Affiliated tissues include cervix, and related phenotype is digestive/alimentary.

Related Diseases for Early Invasive Cervical Adenocarcinoma

Diseases in the Cervical Adenocarcinoma family:

Early Invasive Cervical Adenocarcinoma

Diseases related to Early Invasive Cervical Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 66)
# Related Disease Score Top Affiliating Genes
1 cervical adenocarcinoma 30.1 INSM1 CDKN2A
2 adenocarcinoma 10.0
3 suppressor of tumorigenicity 3 9.9 CDKN2A BCL2
4 gallbladder small cell carcinoma 9.9 CDKN2A BCL2
5 borst-jadassohn intraepidermal carcinoma 9.9 CDKN2A BCL2
6 hypopharynx cancer 9.9 CDKN2A BCL2
7 respiratory system benign neoplasm 9.9 CDKN2A BCL2
8 actinic keratosis 9.9 CDKN2A BCL2
9 keratosis 9.9 CDKN2A BCL2
10 uterine benign neoplasm 9.9 CDKN2A BCL2
11 reproductive organ benign neoplasm 9.9 CDKN2A BCL2
12 female breast cancer 9.9 CDKN2A BCL2
13 oropharynx cancer 9.8 CDKN2A BCL2
14 childhood acute lymphocytic leukemia 9.8 CDKN2A BCL2
15 muscle cancer 9.8 CDKN2A BCL2
16 intestinal benign neoplasm 9.8 CDKN2A BCL2
17 endometrial hyperplasia 9.8 CDKN2A BCL2
18 mature b-cell neoplasm 9.8 CDKN2A BCL2
19 leiomyosarcoma 9.8 CDKN2A BCL2
20 plasmacytoma 9.8 CDKN2A BCL2
21 teratoma 9.8 CDKN2A BCL2
22 liposarcoma 9.8 CDKN2A BCL2
23 retinal cancer 9.8 CDKN2A BCL2
24 colonic benign neoplasm 9.8 CDKN2A BCL2
25 malignant pleural mesothelioma 9.8 CDKN2A BCL2
26 tongue disease 9.8 CDKN2A BCL2
27 papillary squamous carcinoma 9.8 INSM1 CDKN2A
28 thymoma 9.8 CDKN2A BCL2
29 fallopian tube endometrioid adenocarcinoma 9.8 INSM1 CDKN2A
30 chronic cervicitis 9.8 INSM1 CDKN2A
31 li-fraumeni syndrome 9.8 CDKN2A BCL2
32 basaloid squamous cell carcinoma 9.8 INSM1 CDKN2A
33 vaginal cancer 9.8 INSM1 CDKN2A
34 tongue carcinoma 9.8 CDKN2A BCL2
35 uterus carcinoma in situ 9.8 INSM1 CDKN2A
36 cervix uteri carcinoma in situ 9.8 INSM1 CDKN2A
37 adenocarcinoma in situ 9.8 INSM1 CDKN2A
38 breast adenocarcinoma 9.8 CDKN2A BCL2
39 papilloma 9.8 CDKN2A BCL2
40 endocervical carcinoma 9.8 INSM1 CDKN2A
41 mantle cell lymphoma 9.8 CDKN2A BCL2
42 oligodendroglioma 9.8 CDKN2A BCL2
43 endocervical adenocarcinoma 9.8 INSM1 CDKN2A
44 gastric adenocarcinoma 9.8 CDKN2A BCL2
45 paraganglioma 9.8 CDKN2A BCL2
46 hemangioma 9.8 CDKN2A BCL2
47 adenoid cystic carcinoma 9.8 CDKN2A BCL2
48 follicular lymphoma 9.8 CDKN2A BCL2
49 laryngeal squamous cell carcinoma 9.8 CDKN2A BCL2
50 adrenal cortical carcinoma 9.8 CDKN2A BCL2

Graphical network of the top 20 diseases related to Early Invasive Cervical Adenocarcinoma:



Diseases related to Early Invasive Cervical Adenocarcinoma

Symptoms & Phenotypes for Early Invasive Cervical Adenocarcinoma

MGI Mouse Phenotypes related to Early Invasive Cervical Adenocarcinoma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 8.8 BCL2 CDKN2A INSM1

Drugs & Therapeutics for Early Invasive Cervical Adenocarcinoma

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Prevalence of Anal Dysplasia and Anal Cancer in Women With Cervical, Vaginal and Vulvar Dysplasia and Cancer Recruiting NCT02140021

Search NIH Clinical Center for Early Invasive Cervical Adenocarcinoma

Genetic Tests for Early Invasive Cervical Adenocarcinoma

Anatomical Context for Early Invasive Cervical Adenocarcinoma

Organs/tissues related to Early Invasive Cervical Adenocarcinoma:

MalaCards : Cervix

Publications for Early Invasive Cervical Adenocarcinoma

Articles related to Early Invasive Cervical Adenocarcinoma:

# Title Authors PMID Year
1
Surgical treatment and outcome of early invasive adenocarcinoma of the uterine cervix (FIGO stage IA1). 62
28429457 2018
2
[Cervical glandular intraepithelial neoplasia: a clinicopathologic and immunohistochemical analysis of 80 cases]. 62
23611270 2013
3
Early invasive cervical adenocarcinoma: its potential for nodal metastasis or recurrence. 62
12628261 2003
4
Is the invasion depth in millimeters valid to determine the prognosis of early invasive cervical adenocarcinoma? A case of recurrent FIGO stage IA1 cervical adenocarcinoma. 62
11426988 2001
5
Early invasive adenocarcinoma of the cervix. 62
10964335 2000
6
[Retrospective analysis of cytology in a case with early invasive cervical adenocarcinoma]. 62
8568362 1995

Variations for Early Invasive Cervical Adenocarcinoma

Expression for Early Invasive Cervical Adenocarcinoma

Search GEO for disease gene expression data for Early Invasive Cervical Adenocarcinoma.

Pathways for Early Invasive Cervical Adenocarcinoma

GO Terms for Early Invasive Cervical Adenocarcinoma

Biological processes related to Early Invasive Cervical Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of cell growth GO:0030308 9.62 CDKN2A BCL2
2 negative regulation of cell population proliferation GO:0008285 9.55 INSM1 CDKN2A BCL2
3 regulation of protein stability GO:0031647 9.43 CDKN2A BCL2
4 regulation of cell cycle GO:0051726 9.35 INSM1 CDKN2A BCL2
5 apoptotic mitochondrial changes GO:0008637 8.62 CDKN2A BCL2

Sources for Early Invasive Cervical Adenocarcinoma

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....