MCID: ERL004
MIFTS: 30

Early Yaws

Categories: Infectious diseases, Bone diseases

Aliases & Classifications for Early Yaws

MalaCards integrated aliases for Early Yaws:

Name: Early Yaws 12 15 73
Bone and Joint Lesions Due to Yaws 12
Frambesia, Initial or Primary 12
Bone and Joint Yaws Lesion 12
Initial Frambesial Ulcer 12
Initial Lesions of Yaws 12
Initial Lesion of Yaws 73
Primary Frambesia 12
Chancre of Yaws 12

Classifications:



Summaries for Early Yaws

Disease Ontology : 12 A yaws that results in initial papule at the site of entry of bacteria. Without treatment, this is followed by disseminated skin lesions over the body. Bone pain and bone lesions may also occur.

MalaCards based summary : Early Yaws, also known as bone and joint lesions due to yaws, is related to syphilis and syphilitic meningitis. An important gene associated with Early Yaws is EXTL3 (Exostosin Like Glycosyltransferase 3), and among its related pathways/superpathways are Cell adhesion molecules (CAMs) and Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell. Affiliated tissues include bone and skin.

Related Diseases for Early Yaws

Diseases related to Early Yaws via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 169)
# Related Disease Score Top Affiliating Genes
1 syphilis 28.8 CD40LG CD79A EXTL3
2 syphilitic meningitis 10.4 CD40LG EXTL3
3 primary syphilis 10.4 CD40LG EXTL3
4 optic papillitis 10.4 CD40LG EXTL3
5 tertiary syphilis 10.4 CD40LG EXTL3
6 latent syphilis 10.4 CD40LG EXTL3
7 yaws 10.3
8 neuroretinitis 10.2 CD40LG EXTL3
9 selective igg deficiency disease 10.0 CD40LG CD79A
10 c1q nephropathy 10.0 CD40LG CD79A
11 meningovascular neurosyphilis 10.0 CD40LG CD79A
12 alpha chain disease 10.0 CD40LG CD79A
13 brill-zinsser disease 10.0 CD40LG CD79A
14 exudative glomerulonephritis 10.0 CD40LG CD79A
15 cork-handlers' disease 10.0 CD40LG CD79A
16 salpingo-oophoritis 10.0 CD40LG CD79A
17 ventilation pneumonitis 10.0 CD40LG CD79A
18 chronic interstitial cystitis 10.0 CD40LG CD79A
19 axillary adenitis 10.0 CD40LG CD79A
20 cryofibrinogenemia 10.0 CD40LG CD79A
21 trichostrongyloidiasis 10.0 CD40LG CD79A
22 subacute bacterial endocarditis 10.0 CD40LG CD79A
23 heterophyiasis 10.0 CD40LG CD79A
24 immunoglobulin g deficiency 10.0 CD40LG CD79A
25 orbital granuloma 10.0 CD40LG CD79A
26 transient hypogammaglobulinemia of infancy 10.0 CD40LG CD79A
27 hyperglobulinemic purpura 10.0 CD40LG CD79A
28 gastroduodenitis 10.0 CD40LG CD79A
29 bacterial conjunctivitis 10.0 CD40LG CD79A
30 heavy chain disease 10.0 CD40LG CD79A
31 ophthalmia neonatorum 10.0 CD40LG CD79A
32 immunoglobulin a deficiency 1 10.0 CD40LG CD79A
33 parotid disease 10.0 CD40LG CD79A
34 cerebral arteritis 10.0 CD40LG CD79A
35 selective immunoglobulin deficiency disease 10.0 CD40LG CD79A
36 geniculate herpes zoster 10.0 CD40LG CD79A
37 erythema elevatum diutinum 10.0 CD40LG CD79A
38 sporotrichosis 10.0 CD40LG CD79A
39 fallopian tube disease 10.0 CD40LG CD79A
40 hyperimmunoglobulin syndrome 10.0 CD40LG CD79A
41 polyclonal hypergammaglobulinemia 10.0 CD40LG CD79A
42 monoclonal paraproteinemia 10.0 CD40LG CD79A
43 salpingitis 10.0 CD40LG CD79A
44 ocular toxoplasmosis 10.0 CD40LG CD79A
45 dysgammaglobulinemia 10.0 CD40LG CD79A
46 congenital hypogammaglobulinemia 10.0 CD40LG CD79A
47 acute maxillary sinusitis 10.0 CD40LG CD79A
48 chronic polyneuropathy 10.0 CD40LG CD79A
49 spinocerebellar ataxia, autosomal recessive 10 10.0 CD40LG CD79A
50 parasitic ichthyosporea infectious disease 10.0 CD40LG CD79A

Graphical network of the top 20 diseases related to Early Yaws:



Diseases related to Early Yaws

Symptoms & Phenotypes for Early Yaws

Drugs & Therapeutics for Early Yaws

Search Clinical Trials , NIH Clinical Center for Early Yaws

Genetic Tests for Early Yaws

Anatomical Context for Early Yaws

MalaCards organs/tissues related to Early Yaws:

41
Bone, Skin

Publications for Early Yaws

Articles related to Early Yaws:

# Title Authors Year
1
Osteoperiostitis in early yaws: case series and literature review. ( 21367729 )
2011
2
Disseminated early yaws: report of a child with a remarkable genital lesion mimicking venereal syphilis. ( 2343008 )
1990
3
Early yaws: a light microscopic study. ( 2391114 )
1990
4
Radiological and dermatological findings in two patients suffering from early yaws in Indonesia. ( 2391113 )
1990
5
Early yaws, imported in The Netherlands. ( 2583714 )
1989
6
Fluctuations in antibody levels in infection with Treponema pertenue. A four-year follow-up of Karkar islanders with early yaws. ( 6661116 )
1983
7
Case for diagnosis. Disseminated (early) yaws. ( 6798505 )
1981
8
Early yaws. ( 5929695 )
1966
9
A case of early yaws. ( 13618655 )
1959
10
Preliminary and short reports; procaine penicillin in early yaws. ( 14814332 )
1951

Variations for Early Yaws

Expression for Early Yaws

Search GEO for disease gene expression data for Early Yaws.

Pathways for Early Yaws

GO Terms for Early Yaws

Biological processes related to Early Yaws according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 B cell differentiation GO:0030183 8.96 CD40LG CD79A
2 B cell proliferation GO:0042100 8.62 CD40LG CD79A

Sources for Early Yaws

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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