MCID: ECC002
MIFTS: 35

Eccrine Acrospiroma

Categories: Cancer diseases, Endocrine diseases, Skin diseases

Aliases & Classifications for Eccrine Acrospiroma

MalaCards integrated aliases for Eccrine Acrospiroma:

Name: Eccrine Acrospiroma 12 15 17 72
Poroma 12 17 72
Acrospiroma 44 72
Eccrine Hidradenoma of Skin 12
Adenoma, Sweat Gland 72
Eccrine Hidradenoma 12
Eccrine Poroma 72

Classifications:



External Ids:

Disease Ontology 12 DOID:5442
MeSH 44 D018250
NCIt 50 C7568
SNOMED-CT 68 81143000 81393009
UMLS 72 C0019522 C0206671 C1533161 more

Summaries for Eccrine Acrospiroma

MalaCards based summary : Eccrine Acrospiroma, also known as poroma, is related to keratosis and eccrine porocarcinoma. An important gene associated with Eccrine Acrospiroma is KRT15 (Keratin 15), and among its related pathways/superpathways are Developmental Biology and Circadian entrainment. Affiliated tissues include skin, breast and bone, and related phenotype is digestive/alimentary.

Wikipedia : 75 Hidradenoma refers to a benign adnexal tumor of the apical sweat gland. These are 1-3 cm translucent... more...

Related Diseases for Eccrine Acrospiroma

Diseases related to Eccrine Acrospiroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 133)
# Related Disease Score Top Affiliating Genes
1 keratosis 31.2 KRT9 KRT10
2 eccrine porocarcinoma 31.0 LGR6 KRT15
3 bowen's disease 30.7 KRT17 KRT10
4 acanthoma 30.5 KRT17 KRT10
5 keratosis, seborrheic 30.3 KRT5 KRT17 KRT10
6 hidradenocarcinoma 29.9 TP53 KRT5
7 sweat gland cancer 29.8 TP53 KRT5 KRT15
8 papilloma 29.5 TP53 KRT5 KRT10
9 basal cell carcinoma 29.5 TP53 KRT17 KRT15 KRT10
10 keratoacanthoma 29.1 TP53 KRT17 KRT10
11 actinic keratosis 28.8 TP53 LUM KRT17
12 malignant acrospiroma 12.6
13 acrospiroma 12.0
14 clear cell hidradenoma 11.9
15 hidradenoma 11.8
16 nodular hidradenoma 11.4
17 vulvar nodular hidradenoma 11.2
18 pulmonary alveolar microlithiasis 10.4
19 inverted follicular keratosis 10.4
20 apocrine sweat gland neoplasm 10.4 KRT5 KRT15
21 apocrine adenocarcinoma 10.4 KRT5 KRT15
22 rare tumor 10.3
23 epidermolysis bullosa simplex with mottled pigmentation 10.3 KRT5 KRT10
24 pyogenic granuloma 10.3
25 epidermolysis bullosa simplex 10.3 KRT5 KRT10
26 malignant biphasic mesothelioma 10.3 KRT5 KRT10
27 gastric squamous cell carcinoma 10.3 KRT5 KRT10
28 epidermolysis bullosa simplex, dowling-meara type 10.3 KRT5 KRT10
29 sweat gland disease 10.3 KRT5 KRT15
30 nodular malignant melanoma 10.3
31 osteomyelitis 10.3
32 melanoma 10.3
33 transitional cell carcinoma 10.3
34 papillary carcinoma 10.3
35 papillary transitional carcinoma 10.3
36 adenoma 10.3
37 soft tissue sarcoma 10.3
38 amelanotic melanoma 10.2
39 nodular basal cell carcinoma 10.2 KRT17 KRT15
40 intraneural perineurioma 10.2 KRT5 KRT10
41 morpheaform basal cell carcinoma 10.2 KRT17 KRT15
42 basal cell carcinoma, infundibulocystic 10.2 KRT17 KRT10
43 steatocystoma multiplex 10.2 KRT17 KRT10
44 syringoma 10.2
45 syringocystadenoma papilliferum 10.2
46 infiltrative basal cell carcinoma 10.2 KRT17 KRT15
47 heart disease 10.1
48 congestive heart failure 10.1
49 nevus, epidermal 10.1
50 graft-versus-host disease 10.1

Graphical network of the top 20 diseases related to Eccrine Acrospiroma:



Diseases related to Eccrine Acrospiroma

Symptoms & Phenotypes for Eccrine Acrospiroma

MGI Mouse Phenotypes related to Eccrine Acrospiroma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.02 KRT15 KRT17 KRT5 LUM TP53

Drugs & Therapeutics for Eccrine Acrospiroma

Search Clinical Trials , NIH Clinical Center for Eccrine Acrospiroma

Cochrane evidence based reviews: acrospiroma

Genetic Tests for Eccrine Acrospiroma

Anatomical Context for Eccrine Acrospiroma

MalaCards organs/tissues related to Eccrine Acrospiroma:

41
Skin, Breast, Bone, Colon, Liver, Bone Marrow, Lymph Node

Publications for Eccrine Acrospiroma

Articles related to Eccrine Acrospiroma:

(show top 50) (show all 467)
# Title Authors PMID Year
1
[Pigmented eccrine poroma on the back]. 38
30910337 2019
2
Altered Rb, p16, and p53 expression is specific for porocarcinoma relative to poroma. 38
31012122 2019
3
Reactive epidermal eccrine proliferation on the foot due to lymphedema: Eccrine poroma or syringofibroadenoma? 38
31386224 2019
4
Recurrent YAP1-MAML2 and YAP1-NUTM1 fusions in poroma and porocarcinoma. 38
31145701 2019
5
The variegated dermoscopic features of pigmented eccrine poroma: a single institution experience. 38
31104461 2019
6
The Incidence of Nonmalignant Diseases among Patients with Suspected Carcinoma of Unknown Primary Site. 38
30713301 2019
7
The transition between a poroma and a porocarcinoma evidenced by the dermoscopy. 38
31090833 2019
8
Eccrine poroma of the nipple: the first reported case. 38
30826784 2019
9
Initial Misidentification of Thumb Poroma by Shave Biopsy. 38
30037763 2019
10
Poromas with large lumens histopathologically mimicking syringocystadenoma papilliferum: Report of three cases. 38
29943807 2019
11
Eccrine porocarcinoma on the cheek. 38
30739434 2019
12
Recurrent Metastatic Eccrine Porocarcinoma: A Case Report and Review of the Literature. 38
30739904 2019
13
Eccrine Poroma of the Vulva. 38
29293123 2019
14
Eccrine intraepidermal poroma of the eyelid. 38
30574914 2019
15
Dermoscopic features of nonpigmented eccrine poroma. 38
30677158 2019
16
Monophasic sarcomatoid eccrine porocarcinoma. Report of a case and literature review. 38
31263860 2019
17
Dermatoscopy: an auxiliary resource for the diagnosis of poroid neoplasms. 38
30484540 2018
18
Eccrine poroma: Insights of its occurrence and differentials in the maxillofacial region. 38
30651691 2018
19
Dermoscopic features and patterns of poromas: a multicentre observational case-control study conducted by the International Dermoscopy Society. 38
29194789 2018
20
Cuticular Poroma: A Poroma Mostly Composed of Cuticular Cells (Cuticuloma). 38
29293126 2018
21
Multiple Eruptive Eccrine Poromas Associated with Chemotherapy and Autologous Bone Marrow Transplantation. 38
30050816 2018
22
Homeobox transcriptional factor engrailed homeobox 1 is expressed specifically in normal and neoplastic sweat gland cells. 38
29436004 2018
23
Holocrine Poroma: A Distinctive Adnexal Tumor. 38
29095742 2018
24
Eccrine Poroma with Rapid Growth during Pregnancy: A Case Report and Review of the Literature. 38
29606822 2018
25
Pigmented poroma on the temporal region dermoscopically mimicking basal cell carcinoma: A report of two cases. 38
29139150 2018
26
A synchronous incidence of eccrine porocarcinoma of the forearm and facial squamous cell carcinoma: A case report. 38
29245095 2018
27
Cytomorphology of Skin Adnexal Tumors: A Tale of Two Scalp Swellings. 38
29403175 2018
28
Periungual Eccrine Poroma Masquerading as Ingrown Toenails A Case Report with Dermoscopic Findings. 38
29252016 2017
29
Eosinophilic variant of eccrine porocarcinoma of the scalp: Case report and review of the literature. 38
28831427 2017
30
[External nose eccrine poromaļ¼ša case report]. 38
29798176 2017
31
Reticulated acanthoma with sebaceous differentiation mimicking melanoma. 38
29085717 2017
32
Concomitant poroma and porocarcinoma. 38
28954110 2017
33
Large Eccrine Acrospiroma of the Hand. 38
28892973 2017
34
Clinicopathological analysis of 384 cases of poroid neoplasms including 98 cases of apocrine type cases. 38
27177596 2017
35
Eccrine poroma with calcification and metaplastic ossification. 38
27237046 2017
36
Eccrine Poroma of the Postauricular Area. 38
28913302 2017
37
Poroid Condyloma Versus Poroma With Atypias Because of Human Papillomavirus Infection. 38
28177975 2017
38
Vulvar eccrine porocarcinoma: report of a case and literature review. 38
29556664 2017
39
A Large Lumbar Adnexal Neoplasm Presenting Characteristics of Eccrine Poroma and Poroid Hidradenoma. 38
29057137 2017
40
An uncommon presentation of eccrine poroma. 38
27990401 2016
41
Eccrine poroma: correlation of reflectance confocal microscopy and histopathology of horizontal sections. 38
26551629 2016
42
Eccrine poroma: the great dermoscopic imitator. 38
26333195 2016
43
Pigmented eccrine poroma: dermoscopic and confocal features. 38
27648386 2016
44
Malignant Eccrine Poroma of the Vulva: An Intriguing Case of a Rare Tumor at an Unusual Site. 38
27512190 2016
45
Dermoscopy of Skin Adnexal Neoplasms:A Continuous Challenge. 38
27477180 2016
46
"Pseudo-Circumscribed Palmar or Plantar Hypokeratosis (Pseudo-CPH)": a Histologic Pattern Secondary to Trauma; Further Characterization of a Known Entity. 38
27097239 2016
47
Porocarcinomas harbor recurrent HRAS-activating mutations and tumor suppressor inactivating mutations. 38
27067779 2016
48
Eccrine porocarcinoma shares dermoscopic characteristics with eccrine poroma: A report of three cases and review of the published work. 38
26333057 2016
49
Pigmented eccrine poroma of the palm clinically mimicking a seborrheic keratosis. 38
27222880 2016
50
Intraepidermal benign sebaceous neoplasm: apocrine poroma (hidroacanthoma simplex type) with extensive sebaceous differentiation with sebaceoma-like features. 38
26282586 2016

Variations for Eccrine Acrospiroma

Expression for Eccrine Acrospiroma

Search GEO for disease gene expression data for Eccrine Acrospiroma.

Pathways for Eccrine Acrospiroma

GO Terms for Eccrine Acrospiroma

Cellular components related to Eccrine Acrospiroma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.43 LUM KRT9 KRT5 KRT17 KRT15 KRT10
2 intermediate filament GO:0005882 9.02 KRT9 KRT5 KRT17 KRT15 KRT10

Biological processes related to Eccrine Acrospiroma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 epidermis development GO:0008544 9.46 KRT9 KRT5 KRT17 KRT15
2 keratinization GO:0031424 9.35 KRT9 KRT5 KRT17 KRT15 KRT10
3 cytoskeleton organization GO:0007010 9.32 KRT5 KRT15
4 intermediate filament organization GO:0045109 9.26 KRT9 KRT17
5 cornification GO:0070268 9.02 KRT9 KRT5 KRT17 KRT15 KRT10

Molecular functions related to Eccrine Acrospiroma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 scaffold protein binding GO:0097110 8.96 KRT5 KRT15
2 structural constituent of cytoskeleton GO:0005200 8.92 KRT9 KRT5 KRT17 KRT15

Sources for Eccrine Acrospiroma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
Content
Loading form....