MCID: ECC002
MIFTS: 38

Eccrine Acrospiroma

Categories: Cancer diseases, Endocrine diseases, Skin diseases

Aliases & Classifications for Eccrine Acrospiroma

MalaCards integrated aliases for Eccrine Acrospiroma:

Name: Eccrine Acrospiroma 12 15 17 74
Poroma 12 17 74
Acrospiroma 45 74
Eccrine Hidradenoma of Skin 12
Adenoma, Sweat Gland 74
Eccrine Hidradenoma 12
Eccrine Poroma 74

Classifications:



External Ids:

Disease Ontology 12 DOID:5442
MeSH 45 D018250
NCIt 51 C7568
SNOMED-CT 69 81143000 81393009

Summaries for Eccrine Acrospiroma

MalaCards based summary : Eccrine Acrospiroma, also known as poroma, is related to bowen's disease and keratosis. An important gene associated with Eccrine Acrospiroma is LUM (Lumican), and among its related pathways/superpathways are Developmental Biology and Circadian entrainment. Affiliated tissues include skin, breast and liver, and related phenotypes are digestive/alimentary and pigmentation

Wikipedia : 77 Hidradenoma refers to a benign adnexal tumor of the apical sweat gland. These are 1–3 cm translucent... more...

Related Diseases for Eccrine Acrospiroma

Diseases related to Eccrine Acrospiroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 73)
# Related Disease Score Top Affiliating Genes
1 bowen's disease 30.4 KRT10 KRT17
2 keratosis 30.3 KRT10 KRT9
3 acanthoma 30.1 KRT10 KRT17
4 keratosis, seborrheic 29.9 KRT10 KRT17
5 sweat gland cancer 29.5 KRT15 TP53
6 basal cell carcinoma 29.3 KRT10 KRT15 KRT17 TP53
7 malignant acrospiroma 12.5
8 hidradenocarcinoma 12.0
9 acrospiroma 11.9
10 hidradenoma 11.8
11 clear cell hidradenoma 11.6
12 eccrine porocarcinoma 11.6
13 nodular hidradenoma 11.3
14 vulvar nodular hidradenoma 11.1
15 nodular malignant melanoma 10.2
16 melanoma 10.2
17 transitional cell carcinoma 10.2
18 papillary transitional carcinoma 10.2
19 basal cell carcinoma, infundibulocystic 10.2 KRT10 KRT17
20 large cell acanthoma 10.2 KRT10 KRT17
21 steatocystoma multiplex 10.2 KRT10 KRT17
22 basal cell carcinoma 1 10.1
23 syringocystadenoma papilliferum 10.1
24 vulva squamous cell carcinoma 10.1 KRT17 TP53
25 vulvar intraepithelial neoplasia 10.1 KRT10 TP53
26 cervix uteri carcinoma in situ 10.1 KRT17 TP53
27 rere-related disorders 10.1
28 uterus carcinoma in situ 10.1 KRT17 TP53
29 breast squamous cell carcinoma 10.1 KRT10 TP53
30 palmoplantar keratoderma, bothnian type 10.1 KRT17 KRT9
31 basaloid squamous cell carcinoma 10.1 KRT17 TP53
32 pre-malignant neoplasm 10.0 KRT17 TP53
33 verrucous carcinoma 10.0 KRT10 TP53
34 ampulla of vater cancer 10.0 KRT17 TP53
35 nevus, epidermal 10.0
36 pulmonary alveolar microlithiasis 10.0
37 adenoma 10.0
38 pinguecula 10.0 KRT10 TP53
39 primary cutaneous amyloidosis 10.0 KRT10 KRT17
40 in situ carcinoma 10.0 KRT17 TP53
41 nodular basal cell carcinoma 9.9 KRT15 KRT17
42 morpheaform basal cell carcinoma 9.9 KRT15 KRT17
43 actinic keratosis 9.9 KRT17 LUM TP53
44 palmoplantar keratoderma, epidermolytic 9.9 KRT10 KRT9
45 infiltrative basal cell carcinoma 9.9 KRT15 KRT17
46 conjunctival squamous cell carcinoma 9.9 KRT15 TP53
47 keratoacanthoma 9.9 KRT10 KRT17 TP53
48 breast cancer 9.9
49 systemic lupus erythematosus 9.9
50 retinoblastoma 9.9

Graphical network of the top 20 diseases related to Eccrine Acrospiroma:



Diseases related to Eccrine Acrospiroma

Symptoms & Phenotypes for Eccrine Acrospiroma

MGI Mouse Phenotypes related to Eccrine Acrospiroma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.26 KRT15 KRT17 LUM TP53
2 pigmentation MP:0001186 8.8 EN1 KRT17 TP53

Drugs & Therapeutics for Eccrine Acrospiroma

Search Clinical Trials , NIH Clinical Center for Eccrine Acrospiroma

Cochrane evidence based reviews: acrospiroma

Genetic Tests for Eccrine Acrospiroma

Anatomical Context for Eccrine Acrospiroma

MalaCards organs/tissues related to Eccrine Acrospiroma:

42
Skin, Breast, Liver, Colon, Bone, Lymph Node, Eye

Publications for Eccrine Acrospiroma

Articles related to Eccrine Acrospiroma:

(show top 50) (show all 213)
# Title Authors Year
1
Eccrine Poroma of the Vulva. ( 29293123 )
2019
2
Eccrine intraepidermal poroma of the eyelid. ( 30574914 )
2019
3
Dermoscopic features of nonpigmented eccrine poroma. ( 30677158 )
2019
4
Eccrine poroma of the nipple: the first reported case. ( 30826784 )
2019
5
Pigmented poroma on the temporal region dermoscopically mimicking basal cell carcinoma: A report of two cases. ( 29139150 )
2018
6
Holocrine Poroma: A Distinctive Adnexal Tumor. ( 29095742 )
2018
7
Cuticular Poroma: A Poroma Mostly Composed of Cuticular Cells (Cuticuloma). ( 29293126 )
2018
8
Eccrine Poroma with Rapid Growth during Pregnancy: A Case Report and Review of the Literature. ( 29606822 )
2018
9
Initial Misidentification of Thumb Poroma by Shave Biopsy. ( 30037763 )
2018
10
Eccrine poroma: Insights of its occurrence and differentials in the maxillofacial region. ( 30651691 )
2018
11
Large Eccrine Acrospiroma of the Hand. ( 28892973 )
2017
12
Eccrine poroma with calcification and metaplastic ossification. ( 27237046 )
2017
13
Poroid Condyloma Versus Poroma With Atypias Because of Human Papillomavirus Infection. ( 28177975 )
2017
14
Eccrine Poroma of the Postauricular Area. ( 28913302 )
2017
15
Concomitant poroma and porocarcinoma. ( 28954110 )
2017
16
Periungual Eccrine Poroma Masquerading as Ingrown Toenails A Case Report with Dermoscopic Findings. ( 29252016 )
2017
17
Pigmented eccrine poroma of the palm clinically mimicking a seborrheic keratosis. ( 27222880 )
2016
18
Intraepidermal benign sebaceous neoplasm: apocrine poroma (hidroacanthoma simplex type) with extensive sebaceous differentiation with sebaceoma-like features. ( 26282586 )
2016
19
Eccrine poroma: the great dermoscopic imitator. ( 26333195 )
2016
20
Eccrine poroma: correlation of reflectance confocal microscopy and histopathology of horizontal sections. ( 26551629 )
2016
21
Pediatric Dermatology Photoquiz: An Ulcerated Nodule on the Abdomen of a Child. Eccrine poroma. ( 26758093 )
2016
22
Eccrine Poroma Arising within Nevus Sebaceous. ( 27194975 )
2016
23
Malignant Eccrine Poroma of the Vulva: An Intriguing Case of a Rare Tumor at an Unusual Site. ( 27512190 )
2016
24
Pigmented eccrine poroma: dermoscopic and confocal features. ( 27648386 )
2016
25
An uncommon presentation of eccrine poroma. ( 27990401 )
2016
26
Cytological features of malignant eccrine acrospiroma presenting as a soft tissue mass axilla: A rare sweat gland tumor with histologic correlation. ( 26097826 )
2015
27
Poroma with sebaceous differentiation: dermoscopy for the diagnosis of skin tumor with sebaceous differentiation. ( 25657405 )
2015
28
Periungual eccrine poroma. ( 25775671 )
2015
29
Eccrine poroma on the helix: a rare anatomical presentation. ( 25831955 )
2015
30
Clinical and dermoscopic features of eccrine poroma. ( 25851755 )
2015
31
Eccrine Poroma of the External Auditory Canal. ( 25923123 )
2015
32
Case of pigmented eccrine poroma macroscopically simulated a malignant neoplasm with uptake of (18) F-fluorodeoxyglucose on positron emission tomography/computed tomography. ( 26046811 )
2015
33
Eccrine poroma. ( 26225348 )
2015
34
Eccrine poroma and porocarcinoma on the same unusual location: report on two cases. ( 26312678 )
2015
35
A fleshy protuberant growth on the leg. Diagnosis: Eccrine poroma. ( 26515862 )
2015
36
An Unusual Clinical Presentation of Eccrine Poroma Occurring on the Auricle. ( 26538738 )
2015
37
Large pedunculated poroma with apocrine differentiation. ( 23786608 )
2014
38
Case of multiple apocrine poroma in a patient without receiving radiation or chemotherapy. ( 24433245 )
2014
39
Eccrine poroma on the face: an atypical presentation. ( 24470670 )
2014
40
Biopsy-proven pigmented poroma with no vascular structure in dermoscopy. ( 24527868 )
2014
41
Poroma: a review of eccrine, apocrine, and malignant forms. ( 24697501 )
2014
42
Pedunculated poroma on forearm: A rare clinical presentation. ( 25396131 )
2014
43
Periungual eccrine poroma. ( 25483134 )
2014
44
Eccrine poroma of the auricle: a case report. ( 25558412 )
2014
45
A rare combination of sebaceoma with carcinomatous change (sebaceous carcinoma), trichoblastoma, and poroma arising from a nevus sebaceus. ( 23550845 )
2013
46
Eccrine poroma on the postauricular area: a rare presentation. ( 23467402 )
2013
47
Eccrine poroma clinically mimicking ingrowing toenail complicated with granulation tissue. ( 23717023 )
2013
48
Pigmented eccrine poroma: report of an atypical case with the use of dermoscopy. ( 24173189 )
2013
49
Pigmented Eccrine Poroma in abdominal region, a rare presentation. ( 24892457 )
2013
50
Malignant eccrine acrospiroma: a case report. ( 22659768 )
2012

Variations for Eccrine Acrospiroma

Expression for Eccrine Acrospiroma

Search GEO for disease gene expression data for Eccrine Acrospiroma.

Pathways for Eccrine Acrospiroma

Pathways related to Eccrine Acrospiroma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.77 KRT10 KRT15 KRT17 KRT9
2
Show member pathways
12.13 KRT10 KRT15 KRT17 KRT9
3
Show member pathways
11.38 KRT10 KRT15 KRT17 KRT9
4 11.07 KRT17 TP53

GO Terms for Eccrine Acrospiroma

Cellular components related to Eccrine Acrospiroma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.35 KRT10 KRT15 KRT17 KRT9 LUM
2 intermediate filament GO:0005882 8.92 KRT10 KRT15 KRT17 KRT9

Biological processes related to Eccrine Acrospiroma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 epidermis development GO:0008544 9.33 KRT15 KRT17 KRT9
2 intermediate filament organization GO:0045109 9.26 KRT17 KRT9
3 keratinization GO:0031424 9.26 KRT10 KRT15 KRT17 KRT9
4 cornification GO:0070268 8.92 KRT10 KRT15 KRT17 KRT9

Molecular functions related to Eccrine Acrospiroma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural constituent of cytoskeleton GO:0005200 8.8 KRT15 KRT17 KRT9

Sources for Eccrine Acrospiroma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
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31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
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37 IUPHAR
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45 MeSH
46 MESH via Orphanet
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50 NCI
51 NCIt
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55 NINDS
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59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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