MCID: ECC002
MIFTS: 36

Eccrine Acrospiroma

Categories: Cancer diseases, Endocrine diseases, Rare diseases, Skin diseases

Aliases & Classifications for Eccrine Acrospiroma

MalaCards integrated aliases for Eccrine Acrospiroma:

Name: Eccrine Acrospiroma 12 20 15 17 71
Acrospiroma 20 44 71
Poroma 12 17 71
Eccrine Hidradenoma of Skin 12
Adenoma, Sweat Gland 71
Eccrine Hidradenoma 12
Eccrine Poroma 71
Hidradenoma 20

Classifications:



External Ids:

Disease Ontology 12 DOID:5442
MeSH 44 D018250
NCIt 50 C7568
SNOMED-CT 67 254719003
UMLS 71 C0019522 C0206671 C1533161 more

Summaries for Eccrine Acrospiroma

MalaCards based summary : Eccrine Acrospiroma, also known as acrospiroma, is related to clear cell hidradenoma and nodular hidradenoma. An important gene associated with Eccrine Acrospiroma is CEACAM5 (CEA Cell Adhesion Molecule 5), and among its related pathways/superpathways are Developmental Biology and Relaxin signaling pathway. Affiliated tissues include skin, bone marrow and lymph node, and related phenotype is digestive/alimentary.

Wikipedia : 74 Hidradenoma refers to a benign adnexal tumor of the apical sweat gland. These are 1-3 cm translucent... more...

Related Diseases for Eccrine Acrospiroma

Diseases related to Eccrine Acrospiroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 368)
# Related Disease Score Top Affiliating Genes
1 clear cell hidradenoma 31.7 PIP MAML2 KRT7 KRT5 CEACAM5
2 nodular hidradenoma 31.7 PIP KRT7 KRT10 CEACAM5
3 syringocystadenoma papilliferum 31.4 PIP KRT19
4 hidradenoma 31.3 PIP MAML2 KRT7 KRT5 KRT15 CEACAM5
5 malignant acrospiroma 31.2 PIP MAML2 KRT7 KRT5 CEACAM5
6 eccrine porocarcinoma 31.2 NUTM1 KRT7 KRT5 KRT19 CEACAM5
7 bowen's disease 30.6 KRT7 KRT10
8 intraductal papilloma 30.4 KRT7 KRT5 KRT14
9 papilloma 30.3 KRT7 KRT5 KRT14 KRT10
10 syringoma 30.2 KRT7 KRT19 CEACAM5
11 spiradenoma 30.1 KRT7 KRT15 KRT14
12 acanthoma 30.1 KRT5 KRT17 KRT10
13 follicular infundibulum tumor 30.1 KRT17 KRT15
14 mammary paget's disease 30.1 PIP KRT7 KRT14
15 ceruminoma 30.0 PIP KRT7 KRT5
16 in situ carcinoma 29.9 KRT5 KRT17 KRT14
17 papillary adenoma 29.9 KRT7 KRT5 CEACAM5
18 mature teratoma 29.9 KRT7 CEACAM5
19 pilar sheath acanthoma 29.9 KRT7 KRT5 KRT15
20 ductal carcinoma in situ 29.8 PIP KRT5 KRT14
21 rectum adenocarcinoma 29.8 PIP KRT7 CEACAM5
22 vulva cancer 29.8 PIP KRT7 CEACAM5
23 sebaceous adenocarcinoma 29.6 PIP KRT5 KRT14
24 paget disease, extramammary 29.6 PIP KRT7 KRT5 CEACAM5
25 papillary adenocarcinoma 29.4 PIP KRT7 KRT19 CEACAM5
26 keratoacanthoma 29.4 KRT17 KRT15 KRT14 KRT10
27 keratosis 29.4 KRT5 KRT17 KRT14 KRT10
28 skin benign neoplasm 29.4 PIP KRT7 KRT5 KRT14
29 keratosis, seborrheic 29.3 KRT7 KRT5 KRT17 KRT10 CEACAM5
30 sarcomatoid carcinoma 29.3 KRT7 KRT19 KRT14
31 hidrocystoma 29.3 PIP KRT7 KRT19 KRT15 CEACAM5
32 mucoepidermoid carcinoma 29.1 MAML2 KRT7 KRT5 KRT19 KRT14 CEACAM5
33 adenosquamous carcinoma 29.0 MAML2 KRT7 KRT5 KRT19 CEACAM5
34 sweat gland cancer 28.6 PIP KRT7 KRT5 KRT19 KRT15 CEACAM5
35 basal cell carcinoma 28.3 KRT7 KRT5 KRT19 KRT17 KRT15 KRT14
36 skin carcinoma 28.0 PIP KRT7 KRT5 KRT19 KRT17 KRT15
37 eccrine papillary adenoma 27.8 PIP KRT7 KRT5 KRT19 KRT17 KRT15
38 papillary hidradenoma 11.5
39 vulvar nodular hidradenoma 11.1
40 schneiderian carcinoma 10.4 NUTM1 MAML2
41 squamous cell papilloma 10.4
42 mucoepidermoid esophageal carcinoma 10.4 KRT5 CEACAM5
43 breast cystic hypersecretory carcinoma 10.3 KRT5 CEACAM5
44 gallbladder squamous cell carcinoma 10.3 KRT5 CEACAM5
45 vulva basal cell carcinoma 10.3 KRT5 CEACAM5
46 colon leiomyosarcoma 10.3 KRT5 CEACAM5
47 lymphoepithelioma-like thymic carcinoma 10.3 NUTM1 KRT5
48 breast mucoepidermoid carcinoma 10.3 MAML2 KRT5
49 rare tumor 10.3
50 leukoplakia of penis 10.3 KRT7 CEACAM5

Graphical network of the top 20 diseases related to Eccrine Acrospiroma:



Diseases related to Eccrine Acrospiroma

Symptoms & Phenotypes for Eccrine Acrospiroma

MGI Mouse Phenotypes related to Eccrine Acrospiroma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.17 KRT14 KRT15 KRT17 KRT19 KRT5 PIP

Drugs & Therapeutics for Eccrine Acrospiroma

Search Clinical Trials , NIH Clinical Center for Eccrine Acrospiroma

Cochrane evidence based reviews: acrospiroma

Genetic Tests for Eccrine Acrospiroma

Anatomical Context for Eccrine Acrospiroma

MalaCards organs/tissues related to Eccrine Acrospiroma:

40
Skin, Bone Marrow, Lymph Node, Breast, Eye, Smooth Muscle

Publications for Eccrine Acrospiroma

Articles related to Eccrine Acrospiroma:

(show top 50) (show all 487)
# Title Authors PMID Year
1
A rare combination of holocrine poroma with follicular germinative differentiation. 61
33560547 2021
2
A case of YAP1 and NUTM1 rearranged porocarcinoma with corresponding immunohistochemical expression: Review of recent advances in poroma and porocarcinoma pathogenesis with potential diagnostic utility. 61
32757412 2021
3
Eccrine poroma of the eyelid. 61
33120667 2020
4
Utility of YAP1 and NUT immunohistochemistry in the diagnosis of porocarcinoma. 61
33222286 2020
5
Visual Dermatology: Large Eccrine Poroma on the Sole. 61
32955357 2020
6
Morphologic Diversity of Merkel Cell Carcinoma. 61
32833736 2020
7
Characteristic Clinical and Dermoscopic Features of Nonvolar Poroma. 61
32880198 2020
8
Eccrine porocarcinoma: case report and review of the literature. 61
33050682 2020
9
A Growing Mass under the Nail: Subungual Eccrine Poroma. 61
32903899 2020
10
Eyelid Eccrine Poroma: A Case Report and Review of Literature. 61
32742872 2020
11
YAP1-MAML2-Rearranged Poroid Squamous Cell Carcinoma (Squamoid Porocarcinoma) Presenting as a Primary Parotid Gland Tumor. 61
32504288 2020
12
Eccrine Porocarcinoma with Zosteriform Metastasis. 61
32181102 2020
13
Dermatoscopy of the Borst-Jadassohn phenomenon in hidroacanthoma simplex. 61
31932162 2020
14
A rare case of recurrent eccrine poroma underlying gluteal abscess. 61
32911185 2020
15
Reactive epidermal eccrine proliferation on the foot due to lymphedema: Eccrine poroma or syringofibroadenoma? 61
31386224 2019
16
Dermoscopic features of nonpigmented eccrine poroma. 61
30677158 2019
17
Poroma: A case report of pulsatile papule visualized on dermoscopy. 61
31893072 2019
18
Eccrine poromatosis following chemotherapy and radiation therapy. 61
32045152 2019
19
Dermoscopic-Histopathological Correlation of Eccrine Poroma: An Observational Study. 61
31723462 2019
20
[Pigmented eccrine poroma on the back]. 61
30910337 2019
21
Altered Rb, p16, and p53 expression is specific for porocarcinoma relative to poroma. 61
31012122 2019
22
A Painful Step - Pendulating Plantar Eccrine Poroma. 61
31850106 2019
23
The variegated dermoscopic features of pigmented eccrine poroma: a single institution experience. 61
31104461 2019
24
Recurrent YAP1-MAML2 and YAP1-NUTM1 fusions in poroma and porocarcinoma. 61
31145701 2019
25
The Incidence of Nonmalignant Diseases among Patients with Suspected Carcinoma of Unknown Primary Site. 61
30713301 2019
26
Eccrine poroma of the nipple: the first reported case. 61
30826784 2019
27
The transition between a poroma and a porocarcinoma evidenced by the dermoscopy. 61
31090833 2019
28
Initial Misidentification of Thumb Poroma by Shave Biopsy. 61
30037763 2019
29
The transition between a poroma and a porocarcinoma evidenced by the dermoscopy. 61
33261803 2019
30
Eccrine Poroma of the Vulva. 61
29293123 2019
31
Eccrine porocarcinoma on the cheek. 61
30739434 2019
32
Poromas with large lumens histopathologically mimicking syringocystadenoma papilliferum: Report of three cases. 61
29943807 2019
33
Recurrent Metastatic Eccrine Porocarcinoma: A Case Report and Review of the Literature. 61
30739904 2019
34
Monophasic sarcomatoid eccrine porocarcinoma. Report of a case and literature review. 61
31263860 2019
35
Eccrine intraepidermal poroma of the eyelid. 61
30574914 2019
36
Results of Surgical Treatment of Patients with Malignant Eccrine Poroma. 61
33536823 2019
37
Dermatoscopy: an auxiliary resource for the diagnosis of poroid neoplasms. 61
33261770 2018
38
Dermatoscopy: an auxiliary resource for the diagnosis of poroid neoplasms. 61
30484540 2018
39
Eccrine poroma: Insights of its occurrence and differentials in the maxillofacial region. 61
30651691 2018
40
Dermoscopic features and patterns of poromas: a multicentre observational case-control study conducted by the International Dermoscopy Society. 61
29194789 2018
41
Cuticular Poroma: A Poroma Mostly Composed of Cuticular Cells (Cuticuloma). 61
29293126 2018
42
Multiple Eruptive Eccrine Poromas Associated with Chemotherapy and Autologous Bone Marrow Transplantation. 61
30050816 2018
43
Homeobox transcriptional factor engrailed homeobox 1 is expressed specifically in normal and neoplastic sweat gland cells. 61
29436004 2018
44
Holocrine Poroma: A Distinctive Adnexal Tumor. 61
29095742 2018
45
Eccrine Poroma with Rapid Growth during Pregnancy: A Case Report and Review of the Literature. 61
29606822 2018
46
Pigmented poroma on the temporal region dermoscopically mimicking basal cell carcinoma: A report of two cases. 61
29139150 2018
47
A synchronous incidence of eccrine porocarcinoma of the forearm and facial squamous cell carcinoma: A case report. 61
29245095 2018
48
Cytomorphology of Skin Adnexal Tumors: A Tale of Two Scalp Swellings. 61
29403175 2018
49
Periungual Eccrine Poroma Masquerading as Ingrown Toenails A Case Report with Dermoscopic Findings. 61
29252016 2017
50
Eosinophilic variant of eccrine porocarcinoma of the scalp: Case report and review of the literature. 61
28831427 2017

Variations for Eccrine Acrospiroma

Expression for Eccrine Acrospiroma

Search GEO for disease gene expression data for Eccrine Acrospiroma.

Pathways for Eccrine Acrospiroma

Pathways related to Eccrine Acrospiroma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.07 KRT77 KRT7 KRT5 KRT19 KRT17 KRT15
2
Show member pathways
12.36 KRT19 KRT17 KRT15 KRT14 KRT10
3 12.21 KRT7 KRT5 KRT19 KRT17 KRT10
4
Show member pathways
11.68 KRT77 KRT7 KRT5 KRT19 KRT17 KRT15
5
Show member pathways
11.59 KRT7 KRT5 KRT19 KRT17 KRT14
6 11.49 KRT5 KRT17 KRT14
7 11.34 KRT19 KRT17 KRT15 KRT14 KRT10

GO Terms for Eccrine Acrospiroma

Cellular components related to Eccrine Acrospiroma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.61 PIP KRT77 KRT7 KRT5 KRT19 KRT15
2 keratin filament GO:0045095 9.46 KRT77 KRT7 KRT5 KRT14
3 cell periphery GO:0071944 9.43 KRT19 KRT17 KRT14
4 intermediate filament GO:0005882 9.23 KRT77 KRT7 KRT5 KRT19 KRT17 KRT15

Biological processes related to Eccrine Acrospiroma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 keratinization GO:0031424 9.56 KRT77 KRT7 KRT5 KRT19 KRT17 KRT15
2 epidermis development GO:0008544 9.43 KRT5 KRT15 KRT14
3 cornification GO:0070268 9.23 KRT77 KRT7 KRT5 KRT19 KRT17 KRT15
4 hemidesmosome assembly GO:0031581 9.16 KRT5 KRT14

Molecular functions related to Eccrine Acrospiroma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural constituent of cytoskeleton GO:0005200 9.26 KRT5 KRT19 KRT15 KRT14
2 structural molecule activity GO:0005198 9.02 KRT19 KRT17 KRT15 KRT14 KRT10

Sources for Eccrine Acrospiroma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....