MCID: ECC006
MIFTS: 21

Eccrine Mixed Tumor of Skin

Categories: Cancer diseases, Skin diseases

Aliases & Classifications for Eccrine Mixed Tumor of Skin

MalaCards integrated aliases for Eccrine Mixed Tumor of Skin:

Name: Eccrine Mixed Tumor of Skin 12 15 70
Mixed Eccrine Neoplasm of the Skin 12
Eccrine Mixed Tumour of Skin 12
Eccrine Mixed Tumour 12
Eccrine Mixed Tumor 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2079
NCIt 50 C4474
SNOMED-CT 67 254720009
UMLS 70 C0346026

Summaries for Eccrine Mixed Tumor of Skin

MalaCards based summary : Eccrine Mixed Tumor of Skin, also known as mixed eccrine neoplasm of the skin, is related to breast sarcoma and sebaceous breast carcinoma. An important gene associated with Eccrine Mixed Tumor of Skin is PECAM1 (Platelet And Endothelial Cell Adhesion Molecule 1), and among its related pathways/superpathways is Cell surface interactions at the vascular wall. Affiliated tissues include skin, breast and thyroid.

Related Diseases for Eccrine Mixed Tumor of Skin

Diseases related to Eccrine Mixed Tumor of Skin via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 69)
# Related Disease Score Top Affiliating Genes
1 breast sarcoma 10.0 PECAM1 ERBB2
2 sebaceous breast carcinoma 9.9 ERBB2 CEACAM5
3 parotid gland adenoid cystic carcinoma 9.9 ERBB2 CEACAM5
4 laryngeal mucoepidermoid carcinoma 9.9 ERBB2 CEACAM5
5 mucoepidermoid carcinoma 9.9 ERBB2 CEACAM5
6 breast cystic hypersecretory carcinoma 9.9 ERBB2 CEACAM5
7 vulva basal cell carcinoma 9.9 ERBB2 CEACAM5
8 vulva adenocarcinoma 9.9 ERBB2 CEACAM5
9 vulval paget's disease 9.9 ERBB2 CEACAM5
10 gastric diffuse adenocarcinoma 9.9 ERBB2 CEACAM5
11 linitis plastica 9.9 ERBB2 CEACAM5
12 esophageal adenosquamous carcinoma 9.9 ERBB2 CEACAM5
13 intracystic papillary adenoma 9.9 ERBB2 CEACAM5
14 apocrine sweat gland neoplasm 9.9 ERBB2 CEACAM5
15 vulvar disease 9.9 ERBB2 CEACAM5
16 paget disease, extramammary 9.9 ERBB2 CEACAM5
17 mature teratoma 9.9 ERBB2 CEACAM5
18 endocervical carcinoma 9.9 ERBB2 CEACAM5
19 sweat gland cancer 9.9 ERBB2 CEACAM5
20 sweat gland disease 9.9 ERBB2 CEACAM5
21 thoracic benign neoplasm 9.9 ERBB2 CEACAM5
22 breast benign neoplasm 9.9 ERBB2 CEACAM5
23 mixed cell type cancer 9.9 ERBB2 CEACAM5
24 signet ring cell adenocarcinoma 9.9 ERBB2 CEACAM5
25 blood coagulation disease 9.9 PECAM1 ERBB2
26 microinvasive gastric cancer 9.9 ERBB2 CEACAM5
27 tubular adenocarcinoma 9.9 ERBB2 CEACAM5
28 rectum adenocarcinoma 9.9 ERBB2 CEACAM5
29 tonsil cancer 9.9 ERBB2 CEACAM5
30 ovarian cystadenocarcinoma 9.9 ERBB2 CEACAM5
31 gliosarcoma 9.9 PECAM1 ERBB2
32 cystadenocarcinoma 9.9 ERBB2 CEACAM5
33 vulva cancer 9.8 ERBB2 CEACAM5
34 endocervical adenocarcinoma 9.8 ERBB2 CEACAM5
35 cervical adenocarcinoma 9.8 ERBB2 CEACAM5
36 gallbladder papillary carcinoma 9.8 PECAM1 CEACAM5
37 papillary adenocarcinoma 9.8 ERBB2 CEACAM5
38 colonic lymphangioma 9.8 PECAM1 CEACAM5
39 small intestine cancer 9.8 ERBB2 CEACAM5
40 lymphangioma 9.8 PECAM1 CEACAM5
41 liver leiomyoma 9.8 PECAM1 CEACAM5
42 ampulla of vater cancer 9.8 ERBB2 CEACAM5
43 thyroid angiosarcoma 9.8 PECAM1 CEACAM5
44 mucinous adenocarcinoma 9.8 ERBB2 CEACAM5
45 lymphangitis 9.8 PECAM1 CEACAM5
46 ovary adenocarcinoma 9.8 ERBB2 CEACAM5
47 benign peritoneal mesothelioma 9.8 PECAM1 CEACAM5
48 ovarian serous cystadenocarcinoma 9.8 ERBB2 CEACAM5
49 large cell carcinoma 9.8 ERBB2 CEACAM5
50 bile duct adenocarcinoma 9.8 ERBB2 CEACAM5

Graphical network of the top 20 diseases related to Eccrine Mixed Tumor of Skin:



Diseases related to Eccrine Mixed Tumor of Skin

Symptoms & Phenotypes for Eccrine Mixed Tumor of Skin

Drugs & Therapeutics for Eccrine Mixed Tumor of Skin

Search Clinical Trials , NIH Clinical Center for Eccrine Mixed Tumor of Skin

Genetic Tests for Eccrine Mixed Tumor of Skin

Anatomical Context for Eccrine Mixed Tumor of Skin

MalaCards organs/tissues related to Eccrine Mixed Tumor of Skin:

40
Skin, Breast, Thyroid, Ovary, Small Intestine, Colon, Liver

Publications for Eccrine Mixed Tumor of Skin

Articles related to Eccrine Mixed Tumor of Skin:

# Title Authors PMID Year
1
Cutaneous apocrine mixed tumor with intravascular tumor deposits: a diagnostic pitfall. 61
21785330 2011
2
Cutaneous mixed tumor, eccrine variant: a clinicopathologic and immunohistochemical study of 50 cases, with emphasis on unusual histopathologic features. 61
21697702 2011

Variations for Eccrine Mixed Tumor of Skin

Expression for Eccrine Mixed Tumor of Skin

Search GEO for disease gene expression data for Eccrine Mixed Tumor of Skin.

Pathways for Eccrine Mixed Tumor of Skin

Pathways related to Eccrine Mixed Tumor of Skin according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
10.87 PECAM1 CEACAM5

GO Terms for Eccrine Mixed Tumor of Skin

Cellular components related to Eccrine Mixed Tumor of Skin according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 basolateral plasma membrane GO:0016323 8.96 ERBB2 CEACAM5
2 integral component of plasma membrane GO:0005887 8.8 PECAM1 ERBB2 CEACAM5

Biological processes related to Eccrine Mixed Tumor of Skin according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell surface receptor signaling pathway GO:0007166 9.26 PECAM1 ERBB2
2 positive regulation of protein phosphorylation GO:0001934 9.16 PECAM1 ERBB2
3 leukocyte migration GO:0050900 8.96 PECAM1 CEACAM5
4 homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 8.62 PECAM1 CEACAM5

Molecular functions related to Eccrine Mixed Tumor of Skin according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transmembrane signaling receptor activity GO:0004888 8.62 PECAM1 ERBB2

Sources for Eccrine Mixed Tumor of Skin

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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