MCID: ECC003
MIFTS: 38

Eccrine Papillary Adenoma

Categories: Cancer diseases, Endocrine diseases, Rare diseases, Skin diseases

Aliases & Classifications for Eccrine Papillary Adenoma

MalaCards integrated aliases for Eccrine Papillary Adenoma:

Name: Eccrine Papillary Adenoma 12 15 74
Papillary Eccrine Adenoma 12 54
Eccrine Papillary Adenoma of Skin 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5446
NCIt 51 C4173
SNOMED-CT 69 10060008
UMLS 74 C0334350

Summaries for Eccrine Papillary Adenoma

Disease Ontology : 12 A eccrine sweat gland neoplasm that is characterized by isolated well-circumscribed dermal nodule existent for a prolonged duration of time.

MalaCards based summary : Eccrine Papillary Adenoma, also known as papillary eccrine adenoma, is related to adenocarcinoma and aggressive digital papillary adenocarcinoma. An important gene associated with Eccrine Papillary Adenoma is KRT14 (Keratin 14), and among its related pathways/superpathways are Developmental Biology and Circadian entrainment. Affiliated tissues include skin, breast and lung, and related phenotypes are Decreased viability and Decreased viability

Wikipedia : 77 Papillary eccrine adenoma is a cutaneous condition characterized by an uncommon benign sweat gland... more...

Related Diseases for Eccrine Papillary Adenoma

Diseases related to Eccrine Papillary Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 122)
# Related Disease Score Top Affiliating Genes
1 adenocarcinoma 30.0 HRAS KRAS PIK3CA
2 aggressive digital papillary adenocarcinoma 29.3 CEACAM5 HRAS KRAS PIK3CA
3 apocrine adenoma 29.0 CEACAM5 HRAS KRAS PIK3CA UBC
4 adenoma 10.8
5 thyroid hurthle cell adenoma 10.3 KRT14 PIK3CA
6 apocrine sweat gland neoplasm 10.3 KRT14 KRT8
7 brooke-spiegler syndrome 10.3 KRT14 KRT8
8 cervical clear cell adenocarcinoma 10.3 KRT14 KRT8
9 odontoma 10.3 KRT14 KRT8
10 breast squamous cell carcinoma 10.3 KRT14 PIK3CA
11 neurenteric cyst 10.3 KRAS KRT8
12 basaloid squamous cell carcinoma 10.3 KRT14 KRT8
13 rare adenocarcinoma of the breast 10.2 KRAS PIK3CA
14 oncocytic breast carcinoma 10.2 KRT14 PIP
15 intraneural perineurioma 10.2 KRT14 KRT8
16 villous adenoma 10.2 KRAS KRT8
17 syringocystadenoma papilliferum 10.2
18 prostate adenoid cystic carcinoma 10.2 HRAS PIK3CA
19 ectrodactyly, ectodermal dysplasia, and cleft lip/palate syndrome 3 10.2 KRAS PIK3CA
20 ethmoid sinus cancer 10.2 HRAS PIK3CA
21 ethmoid sinus adenocarcinoma 10.2 HRAS PIK3CA
22 breast benign neoplasm 10.2 KRT14 PIP
23 thoracic benign neoplasm 10.2 KRT14 PIP
24 undifferentiated pleomorphic sarcoma 10.2 KRAS PIK3CA
25 epithelial-myoepithelial carcinoma 10.2 HRAS KRT14
26 lipid-rich carcinoma 10.2 KRT14 PIP
27 periampullary adenoma 10.2 HRAS KRAS
28 paronychia 10.2 HRAS KRAS
29 schimmelpenning-feuerstein-mims syndrome 10.2 HRAS KRAS
30 bile duct cysts 10.2 HRAS KRAS
31 papillary hidradenoma 10.2 PIK3CA PIP
32 appendix disease 10.1 HRAS KRAS
33 nasal cavity adenocarcinoma 10.1 HRAS KRAS
34 spinal chordoma 10.1 KRT8 PIK3CA
35 secondary hypertrophic osteoarthropathy 10.1 HRAS KRAS
36 anal canal adenocarcinoma 10.1 HRAS KRAS
37 ovarian cystadenocarcinoma 10.1 HRAS KRAS
38 breast fibroadenoma 10.1 KRT14 KRT8
39 colloid carcinoma of the pancreas 10.1 HRAS KRAS
40 pre-malignant neoplasm 10.1 KRT14 PIP
41 primary cutaneous amyloidosis 10.1 KRT14 KRT8
42 pregnancy adenoma 10.1 KRT14 KRT8 PIK3CA
43 core binding factor acute myeloid leukemia 10.1 HRAS KRAS
44 mucinous lung adenocarcinoma 10.1 HRAS KRAS
45 duodenum cancer 10.1 HRAS KRAS
46 liver angiosarcoma 10.1 HRAS KRAS
47 cecum adenocarcinoma 10.1 HRAS KRAS
48 costello syndrome 10.1 HRAS KRAS
49 ovarian clear cell carcinoma 10.1 KRAS PIK3CA
50 skin squamous cell carcinoma 10.1 HRAS PIK3CA

Graphical network of the top 20 diseases related to Eccrine Papillary Adenoma:



Diseases related to Eccrine Papillary Adenoma

Symptoms & Phenotypes for Eccrine Papillary Adenoma

GenomeRNAi Phenotypes related to Eccrine Papillary Adenoma according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00055-A-2 9.89 HRAS KRAS PIK3CA
2 Decreased viability GR00106-A-0 9.89 KRAS
3 Decreased viability GR00221-A-1 9.89 HRAS KRAS PIK3CA
4 Decreased viability GR00221-A-2 9.89 HRAS KRAS PIK3CA
5 Decreased viability GR00221-A-3 9.89 HRAS
6 Decreased viability GR00221-A-4 9.89 PIK3CA
7 Decreased viability GR00301-A 9.89 KRAS
8 Decreased viability GR00381-A-1 9.89 KRAS
9 Decreased viability GR00402-S-2 9.89 HRAS KRAS PIK3CA
10 Increased cell migration GR00055-A-3 8.8 HRAS KRAS PIK3CA

MGI Mouse Phenotypes related to Eccrine Papillary Adenoma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.02 HRAS KRAS KRT14 KRT8 PIP

Drugs & Therapeutics for Eccrine Papillary Adenoma

Search Clinical Trials , NIH Clinical Center for Eccrine Papillary Adenoma

Genetic Tests for Eccrine Papillary Adenoma

Anatomical Context for Eccrine Papillary Adenoma

MalaCards organs/tissues related to Eccrine Papillary Adenoma:

42
Skin, Breast, Lung, Thyroid, Colon, Ovary, Pancreas

Publications for Eccrine Papillary Adenoma

Articles related to Eccrine Papillary Adenoma:

(show all 28)
# Title Authors Year
1
Papillary eccrine adenoma associated with syringocystadenoma papilliferum. ( 29582790 )
2018
2
BRAF and KRAS mutations in tubular apocrine adenoma and papillary eccrine adenoma of the skin. ( 29241739 )
2018
3
Papillary eccrine adenoma should not be mistaken for aggressive digital papillary adenocarcinoma. ( 24274672 )
2014
4
Papillary eccrine adenoma in association with cutaneous horn. ( 17492846 )
2007
5
Papillary eccrine adenoma. ( 17642667 )
2004
6
Mohs micrographic surgery of a papillary eccrine adenoma. ( 12472500 )
2002
7
Mixed syringocystadenoma papilliferum and papillary eccrine adenoma occurring in a scrotal condyloma. ( 10774942 )
2000
8
Papillary eccrine adenoma of the heel: a case report. ( 10949805 )
2000
9
Papillary eccrine adenoma: immunohistochemical study and literature review. ( 9508346 )
1998
10
Papillary eccrine adenoma: an ultrastructural and immunohistochemical study. ( 9793207 )
1998
11
Papillary eccrine adenoma: immunohistochemical studies of keratin expression. ( 9404854 )
1997
12
Papillary eccrine adenoma with a pomegranate-like appearance. ( 9492441 )
1997
13
Papillary eccrine adenoma--a case of cutaneous sweat gland tumor with secretory and ductular differentiation. ( 7697336 )
1994
14
Papillary eccrine adenoma. A case report with immunohistochemical examination. ( 8494116 )
1993
15
Tubular apocrine adenoma and papillary eccrine adenoma. Entities or unity? ( 1566975 )
1992
16
Papillary eccrine adenoma. A histopathological and immunohistochemical study. ( 2013355 )
1991
17
Papillary eccrine adenoma. Immunohistochemical and ultrastructural analyses. ( 2100547 )
1990
18
Papillary eccrine adenoma--a light-microscopic and immunohistochemical study. ( 2279339 )
1990
19
Papillary eccrine adenoma: an electron microscopic study. ( 2754059 )
1989
20
Papillary eccrine adenoma. ( 2853581 )
1988
21
Papillary eccrine adenoma. A light microscopic and immunohistochemical study. ( 3290282 )
1988
22
Papillary eccrine adenoma. Light-microscopic, histochemical, and immunohistochemical studies. ( 3631452 )
1987
23
Papillary eccrine adenoma. A tubulopapillary hidradenoma with eccrine differentiation. ( 3518523 )
1986
24
Papillary eccrine adenoma. ( 6546338 )
1984
25
Papillary eccrine adenoma. ( 7120491 )
1982
26
Papillary eccrine adenoma. ( 7377809 )
1980
27
Papillary eccrine adenoma. ( 677931 )
1978
28
Papillary eccrine adenoma. ( 857729 )
1977

Variations for Eccrine Papillary Adenoma

Expression for Eccrine Papillary Adenoma

Search GEO for disease gene expression data for Eccrine Papillary Adenoma.

Pathways for Eccrine Papillary Adenoma

Pathways related to Eccrine Papillary Adenoma according to GeneCards Suite gene sharing:

(show top 50) (show all 74)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.18 HRAS KRAS KRT14 KRT8 PIK3CA UBC
2
Show member pathways
12.88 HRAS KRAS KRT14 PIK3CA
3
Show member pathways
12.52 HRAS KRAS PIK3CA UBC
4
Show member pathways
12.47 HRAS KRAS PIK3CA
5
Show member pathways
12.43 HRAS KRAS PIK3CA
6
Show member pathways
12.41 HRAS KRAS PIK3CA
7
Show member pathways
12.4 HRAS KRAS PIK3CA
8 12.39 HRAS KRAS PIK3CA
9
Show member pathways
12.38 HRAS KRAS PIK3CA
10
Show member pathways
12.36 HRAS KRAS PIK3CA
11
Show member pathways
12.32 HRAS KRAS PIK3CA
12
Show member pathways
12.31 HRAS KRAS UBC
13
Show member pathways
12.3 HRAS KRAS PIK3CA
14
Show member pathways
12.28 HRAS KRAS PIK3CA
15
Show member pathways
12.28 HRAS KRAS PIK3CA
16
Show member pathways
12.27 HRAS KRAS PIK3CA
17
Show member pathways
12.25 HRAS KRAS PIK3CA
18 12.23 HRAS KRAS PIK3CA
19
Show member pathways
12.19 HRAS PIK3CA UBC
20
Show member pathways
12.19 HRAS KRAS PIK3CA
21
Show member pathways
12.19 HRAS KRAS PIK3CA UBC
22 12.16 HRAS KRAS PIK3CA
23 12.16 HRAS KRAS PIK3CA
24
Show member pathways
12.16 HRAS KRAS PIK3CA UBC
25 12.1 HRAS KRAS PIK3CA
26
Show member pathways
12.08 HRAS KRAS PIK3CA
27
Show member pathways
12.07 HRAS KRAS PIK3CA
28
Show member pathways
12.05 HRAS KRAS PIK3CA
29 12.03 HRAS KRAS PIK3CA
30
Show member pathways
12.02 HRAS KRAS PIK3CA
31
Show member pathways
12.02 HRAS KRAS PIK3CA
32 12 HRAS KRAS PIK3CA
33
Show member pathways
11.99 HRAS KRAS PIK3CA
34
Show member pathways
11.99 HRAS KRAS PIK3CA UBC
35
Show member pathways
11.98 HRAS KRAS PIK3CA
36 11.94 HRAS KRAS PIK3CA
37
Show member pathways
11.93 HRAS KRAS PIK3CA
38
Show member pathways
11.91 HRAS KRAS PIK3CA
39
Show member pathways
11.91 HRAS KRAS PIK3CA UBC
40
Show member pathways
11.89 HRAS KRAS UBC
41 11.87 HRAS KRAS PIK3CA
42 11.82 HRAS KRAS PIK3CA
43
Show member pathways
11.81 CEACAM5 HRAS KRAS PIK3CA
44 11.8 HRAS KRAS PIK3CA
45 11.78 HRAS KRAS PIK3CA
46 11.71 HRAS KRAS PIK3CA
47 11.7 HRAS KRAS PIK3CA
48
Show member pathways
11.65 HRAS KRAS PIK3CA
49
Show member pathways
11.61 HRAS KRAS PIK3CA
50 11.45 HRAS KRAS PIK3CA

GO Terms for Eccrine Papillary Adenoma

Biological processes related to Eccrine Papillary Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.5 KRAS PIK3CA UBC
2 regulation of long-term neuronal synaptic plasticity GO:0048169 9.26 HRAS KRAS
3 negative regulation of anoikis GO:2000811 9.16 CEACAM5 PIK3CA
4 negative regulation of neuron apoptotic process GO:0043524 9.13 HRAS KRAS PIK3CA
5 response to isolation stress GO:0035900 8.62 HRAS KRAS

Sources for Eccrine Papillary Adenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....