MCID: ECC007
MIFTS: 23

Eccrine Sweat Gland Cancer

Categories: Cancer diseases, Endocrine diseases, Skin diseases

Aliases & Classifications for Eccrine Sweat Gland Cancer

MalaCards integrated aliases for Eccrine Sweat Gland Cancer:

Name: Eccrine Sweat Gland Cancer 12 15 17
Malignant Eccrine Skin Neoplasm 12
Malignant Eccrine Tumor 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4921
NCIt 51 C5559
UMLS 74 C1334577

Summaries for Eccrine Sweat Gland Cancer

MalaCards based summary : Eccrine Sweat Gland Cancer, also known as malignant eccrine skin neoplasm, is related to eccrine adenocarcinoma and hidrocystoma. An important gene associated with Eccrine Sweat Gland Cancer is DAND5 (DAN Domain BMP Antagonist Family Member 5), and among its related pathways/superpathways are Developmental Biology and Cytoskeletal Signaling. Affiliated tissues include skin.

Related Diseases for Eccrine Sweat Gland Cancer

Diseases related to Eccrine Sweat Gland Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 174)
# Related Disease Score Top Affiliating Genes
1 eccrine adenocarcinoma 11.4
2 hidrocystoma 10.2 KRT15 KRT7
3 cell type benign neoplasm 10.2 KRT7 TP53
4 malignant ovarian surface epithelial-stromal neoplasm 10.2 KRT7 TP53
5 ovary epithelial cancer 10.2 KRT7 TP53
6 endometrial adenocarcinoma 10.2 KRT7 TP53
7 large cell carcinoma 10.2 KRT5 KRT7
8 carcinosarcoma 10.2 KRT7 TP53
9 bile duct cancer 10.2 KRT7 TP53
10 spiradenoma 10.2 KRT7 TP53
11 conjunctival squamous cell carcinoma 10.2 KRT15 TP53
12 teratoma 10.2 KRT7 TP53
13 apocrine adenocarcinoma 10.2 KRT15 KRT5
14 inverted transitional papilloma 10.2 KRT5 KRT7
15 balloon cell malignant melanoma 10.2 KRT5 KRT7
16 benign breast adenomyoepithelioma 10.2 KRT5 KRT7
17 breast adenomyoepithelioma 10.2 KRT5 KRT7
18 ceruminoma 10.2 KRT5 KRT7
19 benign mesothelioma 10.2 KRT5 KRT7
20 vulvar intraepithelial neoplasia 10.2 KRT7 TP53
21 sensory organ benign neoplasm 10.2 KRT5 KRT7
22 bile duct mucoepidermoid carcinoma 10.2 KRT5 KRT7
23 middle ear adenoma 10.2 KRT5 KRT7
24 large cell acanthoma 10.2 KRT5 KRT7
25 ductal carcinoma in situ 10.2 KRT5 TP53
26 cystadenocarcinoma 10.2 KRT7 TP53
27 bladder carcinoma in situ 10.2 KRT7 TP53
28 vulvar disease 10.2 KRT7 TP53
29 nasal cavity adenocarcinoma 10.2 KRT7 TP53
30 female reproductive endometrioid cancer 10.2 KRT7 TP53
31 malignant biphasic mesothelioma 10.2 KRT5 KRT7
32 peritoneum cancer 10.1 KRT5 KRT7
33 gastric squamous cell carcinoma 10.1 KRT5 KRT7
34 pleomorphic carcinoma 10.1 KRT7 TP53
35 breast myoepithelial neoplasm 10.1 KRT5 KRT7
36 eccrine porocarcinoma 10.1 KRT15 LGR6
37 keratinizing squamous cell carcinoma 10.1 KRT5 TP53
38 lipoadenoma 10.1 KRT5 KRT7
39 nasal cavity squamous cell carcinoma 10.1 KRT5 KRT7
40 atypical choroid plexus papilloma 10.1 KRT5 KRT7
41 breast secretory carcinoma 10.1 KRT5 KRT7
42 epithelial-myoepithelial carcinoma 10.1 KRT7 TP53
43 breast squamous cell carcinoma 10.1 KRT5 TP53
44 pregnancy adenoma 10.1 KRT5 KRT7
45 basaloid squamous cell carcinoma 10.1 KRT7 TP53
46 anus cancer 10.1 KRT5 KRT7
47 mixed cell type cancer 10.1 KRT7 TP53
48 granulosa cell tumor of the ovary 10.1 KRT7 TP53
49 acinar cell carcinoma 10.1 KRT7 TP53
50 intraneural perineurioma 10.1 KRT5 KRT7

Graphical network of the top 20 diseases related to Eccrine Sweat Gland Cancer:



Diseases related to Eccrine Sweat Gland Cancer

Symptoms & Phenotypes for Eccrine Sweat Gland Cancer

Drugs & Therapeutics for Eccrine Sweat Gland Cancer

Search Clinical Trials , NIH Clinical Center for Eccrine Sweat Gland Cancer

Genetic Tests for Eccrine Sweat Gland Cancer

Anatomical Context for Eccrine Sweat Gland Cancer

MalaCards organs/tissues related to Eccrine Sweat Gland Cancer:

42
Skin

Publications for Eccrine Sweat Gland Cancer

Variations for Eccrine Sweat Gland Cancer

Expression for Eccrine Sweat Gland Cancer

Search GEO for disease gene expression data for Eccrine Sweat Gland Cancer.

Pathways for Eccrine Sweat Gland Cancer

Pathways related to Eccrine Sweat Gland Cancer according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.57 DAND5 KRT15 KRT20 KRT5 KRT7
2 11.82 KRT20 KRT5 KRT7
3
Show member pathways
11.38 KRT15 KRT20 KRT5 KRT7

GO Terms for Eccrine Sweat Gland Cancer

Cellular components related to Eccrine Sweat Gland Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intermediate filament GO:0005882 8.92 KRT15 KRT20 KRT5 KRT7

Biological processes related to Eccrine Sweat Gland Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 keratinization GO:0031424 9.26 KRT15 KRT20 KRT5 KRT7
2 cornification GO:0070268 8.92 KRT15 KRT20 KRT5 KRT7

Molecular functions related to Eccrine Sweat Gland Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 scaffold protein binding GO:0097110 8.96 KRT15 KRT5
2 structural constituent of cytoskeleton GO:0005200 8.8 KRT15 KRT20 KRT5

Sources for Eccrine Sweat Gland Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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