MCID: ECC007
MIFTS: 25

Eccrine Sweat Gland Cancer

Categories: Cancer diseases, Endocrine diseases, Skin diseases
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Aliases & Classifications for Eccrine Sweat Gland Cancer

MalaCards integrated aliases for Eccrine Sweat Gland Cancer:

Name: Eccrine Sweat Gland Cancer 11 14 16
Malignant Eccrine Skin Neoplasm 11
Malignant Eccrine Tumor 11

Classifications:



External Ids:

Disease Ontology 11 DOID:4921
NCIt 49 C5559
UMLS 71 C1334577

Summaries for Eccrine Sweat Gland Cancer

MalaCards based summary: Eccrine Sweat Gland Cancer, also known as malignant eccrine skin neoplasm, is related to eccrine adenocarcinoma and basal cell carcinoma. An important gene associated with Eccrine Sweat Gland Cancer is NUTM1 (NUT Midline Carcinoma Family Member 1), and among its related pathways/superpathways are Nervous system development and Keratinization. Affiliated tissues include skin, and related phenotypes are neoplasm and digestive/alimentary

Related Diseases for Eccrine Sweat Gland Cancer

Diseases related to Eccrine Sweat Gland Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 397)
# Related Disease Score Top Affiliating Genes
1 eccrine adenocarcinoma 32.1 PIP KRT7 KRT5 CEACAM5
2 basal cell carcinoma 28.8 TP53 PTGER4 PIP KRT7 KRT5 KRT19
3 sweat gland cancer 28.8 TP53 PIP PHLDA1 MAML2 KRT7 KRT5
4 eccrine sweat gland neoplasm 27.8 YAP1 WWTR1 PIP NUTM1 MAMLD1 MAML2
5 thymus adenocarcinoma 10.4 NUTM1 CEACAM5
6 leukoplakia of penis 10.4 KRT7 CEACAM5
7 urethral villous adenoma 10.4 KRT7 CEACAM5
8 schneiderian carcinoma 10.4 NUTM1 MAML2
9 pancreatic serous cystadenocarcinoma 10.4 KRT7 CEACAM5
10 vaginal tubulovillous adenoma 10.4 KRT7 CEACAM5
11 urinary bladder villous adenoma 10.4 KRT7 CEACAM5
12 lymphoepithelioma-like thymic carcinoma 10.3 NUTM1 KRT5
13 aortic malignant tumor 10.3 KRT7 CEACAM5
14 lacrimal gland mucoepidermoid carcinoma 10.3 MAML2 KRT7
15 female urethral cancer 10.3 KRT7 CEACAM5
16 mucinous ovarian cystadenoma 10.3 KRT7 CEACAM5
17 mucinous adenofibroma 10.3 KRT7 CEACAM5
18 laryngeal adenoid cystic carcinoma 10.3 KRT7 KRT5
19 jejunal cancer 10.3 KRT7 CEACAM5
20 colonic lymphangioma 10.3 KRT7 CEACAM5
21 internal hemorrhoid 10.3 KRT7 CEACAM5
22 inverted transitional papilloma 10.3 KRT7 KRT5
23 hemorrhoid 10.3 KRT7 CEACAM5
24 mucinous intrahepatic cholangiocarcinoma 10.3 KRT7 CEACAM5
25 lung adenoid cystic carcinoma 10.3 MAML2 KRT7
26 bile duct cystadenocarcinoma 10.3 KRT7 CEACAM5
27 rectosigmoid junction neoplasm 10.3 KRT7 CEACAM5
28 sigmoid neoplasm 10.3 KRT7 CEACAM5
29 appendiceal neoplasm 10.3 KRT7 CEACAM5
30 microinvasive cervical squamous cell carcinoma 10.3 KRT7 KRT5
31 subareolar duct papillomatosis 10.3 KRT7 KRT5
32 prostatic urethral cancer 10.3 KRT7 KRT5
33 clear cell acanthoma 10.3 KRT5 CEACAM5
34 nipple benign neoplasm 10.3 KRT7 KRT5
35 krukenberg carcinoma 10.3 KRT7 CEACAM5
36 rectum squamous cell carcinoma 10.3 KRT7 KRT5
37 middle ear adenoma 10.3 KRT7 KRT5
38 auditory system benign neoplasm 10.3 KRT7 KRT5
39 papillary squamous carcinoma 10.3 KRT7 KRT5
40 follicular infundibulum tumor 10.3 PHLDA1 KRT15
41 ascending colon cancer 10.3 KRT7 CEACAM5
42 benign breast adenomyoepithelioma 10.3 KRT7 KRT5
43 breast adenomyoepithelioma 10.3 KRT7 KRT5
44 sebaceous breast carcinoma 10.3 PIP CEACAM5
45 pilar sheath acanthoma 10.3 PHLDA1 KRT15
46 morpheaform basal cell carcinoma 10.3 PHLDA1 KRT15
47 lipoadenoma 10.3 MAML2 KRT5
48 breast myoepithelial neoplasm 10.3 KRT7 KRT5
49 epidermal appendage tumor 10.3 PHLDA1 KRT15
50 ovarian mucinous neoplasm 10.3 KRT7 CEACAM5

Graphical network of the top 20 diseases related to Eccrine Sweat Gland Cancer:



Diseases related to Eccrine Sweat Gland Cancer

Symptoms & Phenotypes for Eccrine Sweat Gland Cancer

MGI Mouse Phenotypes related to Eccrine Sweat Gland Cancer:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 9.63 CAMTA1 CEACAM5 KRT19 PTGER4 TP53 YAP1
2 digestive/alimentary MP:0005381 9.56 CEACAM5 KRT15 KRT19 KRT5 PIP TP53
3 immune system MP:0005387 9.32 CEACAM5 KRT19 KRT5 MAMLD1 PHLDA1 PIP

Drugs & Therapeutics for Eccrine Sweat Gland Cancer

Search Clinical Trials, NIH Clinical Center for Eccrine Sweat Gland Cancer

Genetic Tests for Eccrine Sweat Gland Cancer

Anatomical Context for Eccrine Sweat Gland Cancer

Organs/tissues related to Eccrine Sweat Gland Cancer:

MalaCards : Skin

Publications for Eccrine Sweat Gland Cancer

Articles related to Eccrine Sweat Gland Cancer:

# Title Authors PMID Year
1
Malignant eccrine tumor--a case report and a classification of tumors of eccrine sweat apparatus. 62
2229655 1990
2
[Ultrastructural aspects of the histogenesis and diagnosis of cancer of eccrine sweat gland cancer in man]. 62
3799045 1986

Variations for Eccrine Sweat Gland Cancer

Expression for Eccrine Sweat Gland Cancer

Search GEO for disease gene expression data for Eccrine Sweat Gland Cancer.

Pathways for Eccrine Sweat Gland Cancer

GO Terms for Eccrine Sweat Gland Cancer

Cellular components related to Eccrine Sweat Gland Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intermediate filament GO:0005882 9.23 KRT7 KRT5 KRT19 KRT15

Biological processes related to Eccrine Sweat Gland Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 heart process GO:0003015 9.46 YAP1 WWTR1
2 regulation of metanephric nephron tubule epithelial cell differentiation GO:0072307 9.26 YAP1 WWTR1
3 intermediate filament organization GO:0045109 9.23 KRT7 KRT5 KRT19 KRT15

Sources for Eccrine Sweat Gland Cancer

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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