MCID: ECC008
MIFTS: 25

Eccrine Sweat Gland Neoplasm

Categories: Cancer diseases, Endocrine diseases, Skin diseases

Aliases & Classifications for Eccrine Sweat Gland Neoplasm

MalaCards integrated aliases for Eccrine Sweat Gland Neoplasm:

Name: Eccrine Sweat Gland Neoplasm 12 15
Malignant Eccrine Neoplasm 74
Eccrine Skin Neoplasm 12
Eccrine Neoplasm 74
Eccrine Tumor 12

Classifications:



External Ids:

Disease Ontology 12 DOID:173
NCIt 51 C6796

Summaries for Eccrine Sweat Gland Neoplasm

MalaCards based summary : Eccrine Sweat Gland Neoplasm, also known as malignant eccrine neoplasm, is related to schopf-schulz-passarge syndrome and eccrine sweat gland cancer. An important gene associated with Eccrine Sweat Gland Neoplasm is LUM (Lumican), and among its related pathways/superpathways are Developmental Biology and Circadian entrainment. Affiliated tissues include skin.

Related Diseases for Eccrine Sweat Gland Neoplasm

Diseases related to Eccrine Sweat Gland Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 106)
# Related Disease Score Top Affiliating Genes
1 schopf-schulz-passarge syndrome 11.3
2 eccrine sweat gland cancer 11.3
3 acanthoma 10.3 KRT10 KRT17
4 basal cell carcinoma, infundibulocystic 10.3 KRT10 KRT17
5 steatocystoma multiplex 10.3 KRT10 KRT17
6 palmoplantar keratoderma, bothnian type 10.2 KRT17 KRT9
7 keratosis, seborrheic 10.2 KRT10 KRT17
8 vulva squamous cell carcinoma 10.2 KRT17 TP53
9 cervix uteri carcinoma in situ 10.2 KRT17 TP53
10 keratosis 10.2 KRT10 KRT9
11 uterus carcinoma in situ 10.2 KRT17 TP53
12 breast squamous cell carcinoma 10.2 KRT10 TP53
13 clear cell basal cell carcinoma 10.2 KRT17 KRT7
14 pre-malignant neoplasm 10.2 KRT17 TP53
15 verrucous carcinoma 10.2 KRT10 TP53
16 pinguecula 10.1 KRT10 TP53
17 ampulla of vater adenocarcinoma 10.1 KRT17 KRT7
18 nodular hidradenoma 10.1 KRT10 KRT7
19 ovarian mucinous neoplasm 10.1 KRT17 KRT7
20 malignant biphasic mesothelioma 10.1 KRT10 KRT7
21 pregnancy adenoma 10.1 KRT17 KRT7
22 gastric squamous cell carcinoma 10.1 KRT10 KRT7
23 mucinous tubular and spindle renal cell carcinoma 10.1 KRT10 KRT7
24 in situ carcinoma 10.1 KRT17 TP53
25 palmoplantar keratoderma, epidermolytic 10.1 KRT10 KRT9
26 intraneural perineurioma 10.1 KRT10 KRT7
27 ileum cancer 10.1 KRT10 KRT7
28 malignant spiradenoma 10.1 KRT7 TP53
29 spiradenoma 10.1 KRT7 TP53
30 pericardial mesothelioma 10.1 KRT10 KRT7
31 white sponge nevus 1 10.1 KRT10 KRT7
32 bladder carcinoma in situ 10.1 KRT7 TP53
33 vulvar disease 10.1 KRT7 TP53
34 papillary serous adenocarcinoma 10.1 KRT7 TP53
35 nasal cavity adenocarcinoma 10.1 KRT7 TP53
36 female reproductive endometrioid cancer 10.1 KRT7 TP53
37 glycogen-rich clear cell breast carcinoma 10.1 KRT7 TP53
38 prostate squamous cell carcinoma 10.1 KRT7 TP53
39 pleomorphic carcinoma 10.1 KRT7 TP53
40 biliary papillomatosis 10.1 KRT7 TP53
41 endocervical adenocarcinoma 10.1 KRT7 TP53
42 cervical adenocarcinoma 10.1 KRT7 TP53
43 appendix cancer 10.0 KRT7 TP53
44 epithelial-myoepithelial carcinoma 10.0 KRT7 TP53
45 nodular basal cell carcinoma 10.0 KRT15 KRT17
46 necrotizing sialometaplasia 10.0 KRT7 TP53
47 morpheaform basal cell carcinoma 10.0 KRT15 KRT17
48 cystic teratoma 10.0 KRT7 TP53
49 teratoma 10.0 KRT7 TP53
50 mixed cell type cancer 10.0 KRT7 TP53

Graphical network of the top 20 diseases related to Eccrine Sweat Gland Neoplasm:



Diseases related to Eccrine Sweat Gland Neoplasm

Symptoms & Phenotypes for Eccrine Sweat Gland Neoplasm

Drugs & Therapeutics for Eccrine Sweat Gland Neoplasm

Search Clinical Trials , NIH Clinical Center for Eccrine Sweat Gland Neoplasm

Genetic Tests for Eccrine Sweat Gland Neoplasm

Anatomical Context for Eccrine Sweat Gland Neoplasm

MalaCards organs/tissues related to Eccrine Sweat Gland Neoplasm:

42
Skin

Publications for Eccrine Sweat Gland Neoplasm

Articles related to Eccrine Sweat Gland Neoplasm:

# Title Authors Year
1
Benign chondroid syringoma: atypical presentation of a rare eccrine tumor. ( 21397527 )
2011

Variations for Eccrine Sweat Gland Neoplasm

Expression for Eccrine Sweat Gland Neoplasm

Search GEO for disease gene expression data for Eccrine Sweat Gland Neoplasm.

Pathways for Eccrine Sweat Gland Neoplasm

Pathways related to Eccrine Sweat Gland Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.77 KRT10 KRT15 KRT17 KRT7 KRT9
2
Show member pathways
12.13 KRT10 KRT15 KRT17 KRT9
3 11.92 KRT10 KRT17 KRT7
4
Show member pathways
11.48 KRT10 KRT15 KRT17 KRT7 KRT9

GO Terms for Eccrine Sweat Gland Neoplasm

Cellular components related to Eccrine Sweat Gland Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.43 KRT10 KRT15 KRT17 KRT7 KRT9 LUM
2 intermediate filament GO:0005882 9.02 KRT10 KRT15 KRT17 KRT7 KRT9

Biological processes related to Eccrine Sweat Gland Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 keratinization GO:0031424 9.35 KRT10 KRT15 KRT17 KRT7 KRT9
2 epidermis development GO:0008544 9.33 KRT15 KRT17 KRT9
3 intermediate filament organization GO:0045109 9.26 KRT17 KRT9
4 cornification GO:0070268 9.02 KRT10 KRT15 KRT17 KRT7 KRT9

Molecular functions related to Eccrine Sweat Gland Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural molecule activity GO:0005198 9.13 KRT10 KRT17 KRT7
2 structural constituent of cytoskeleton GO:0005200 8.8 KRT15 KRT17 KRT9

Sources for Eccrine Sweat Gland Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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