MCID: ECC008
MIFTS: 31

Eccrine Sweat Gland Neoplasm

Categories: Cancer diseases, Endocrine diseases, Skin diseases

Aliases & Classifications for Eccrine Sweat Gland Neoplasm

MalaCards integrated aliases for Eccrine Sweat Gland Neoplasm:

Name: Eccrine Sweat Gland Neoplasm 12 15
Eccrine Sweat Gland Cancer 12 15
Malignant Eccrine Skin Neoplasm 12
Malignant Eccrine Neoplasm 73
Malignant Eccrine Tumor 12
Eccrine Skin Neoplasm 12
Eccrine Neoplasm 73
Eccrine Tumor 12

Classifications:



External Ids:

Disease Ontology 12 DOID:173 DOID:4921
NCIt 50 C6796 C5559

Summaries for Eccrine Sweat Gland Neoplasm

MalaCards based summary : Eccrine Sweat Gland Neoplasm, also known as eccrine sweat gland cancer, is related to eccrine adenocarcinoma and schopf-schulz-passarge syndrome. An important gene associated with Eccrine Sweat Gland Neoplasm is KRT15 (Keratin 15), and among its related pathways/superpathways are Developmental Biology and Circadian entrainment. Affiliated tissues include skin, lung and kidney.

Related Diseases for Eccrine Sweat Gland Neoplasm

Diseases related to Eccrine Sweat Gland Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 216)
# Related Disease Score Top Affiliating Genes
1 eccrine adenocarcinoma 11.3
2 schopf-schulz-passarge syndrome 11.3
3 white sponge nevus 1 10.2 KRT10 KRT7
4 pachyonychia congenita 1 10.2 KRT10 KRT17
5 hidrocystoma 10.2 KRT15 KRT7
6 clear cell basal cell carcinoma 10.2 KRT17 KRT7
7 anus cancer 10.2 KRT5 KRT7
8 acanthoma 10.2 KRT10 KRT17
9 atypical choroid plexus papilloma 10.2 KRT5 KRT7
10 spindle cell carcinoma 10.2 KRT5 KRT7
11 breast secretory carcinoma 10.2 KRT5 KRT7
12 nasal cavity squamous cell carcinoma 10.2 KRT5 KRT7
13 breast fibroadenoma 10.2 KRT15 MME
14 nodular basal cell carcinoma 10.2 KRT15 KRT17
15 epidermolysis bullosa simplex, dowling-meara type 10.2 KRT10 KRT5
16 ovarian cancer 1 10.2 KRT7 TP53
17 gastrointestinal system benign neoplasm 10.2 KRT7 TP53
18 biliary tract neoplasm 10.2 KRT7 TP53
19 ovarian clear cell carcinoma 10.2 KRT7 TP53
20 renal oncocytoma 10.2 KRT7 MME
21 vulva cancer 10.2 KRT7 TP53
22 malignant ovarian surface epithelial-stromal neoplasm 10.2 KRT7 TP53
23 ovary epithelial cancer 10.2 KRT7 TP53
24 germ cell and embryonal cancer 10.2 KRT7 TP53
25 papillary adenocarcinoma 10.2 KRT7 TP53
26 nephrogenic adenofibroma 10.2 KRT7 MME
27 acinar cell carcinoma 10.2 KRT7 TP53
28 lung benign neoplasm 10.2 KRT7 TP53
29 ovary adenocarcinoma 10.2 KRT7 TP53
30 collecting duct carcinoma 10.2 KRT7 MME
31 bile duct adenocarcinoma 10.2 KRT7 TP53
32 epithelial-myoepithelial carcinoma 10.2 KRT7 TP53
33 granulosa cell tumor of the ovary 10.2 KRT7 TP53
34 inverted transitional papilloma 10.2 KRT5 KRT7
35 benign breast adenomyoepithelioma 10.2 KRT5 KRT7
36 ceruminoma 10.2 KRT5 KRT7
37 spiradenoma 10.2 KRT7 TP53
38 sensory organ benign neoplasm 10.2 KRT5 KRT7
39 bile duct mucoepidermoid carcinoma 10.2 KRT5 KRT7
40 pinguecula 10.2 KRT10 TP53
41 middle ear adenoma 10.2 KRT5 KRT7
42 verrucous carcinoma 10.2 KRT10 TP53
43 apocrine adenocarcinoma 10.2 KRT15 KRT5
44 steatocystoma multiplex 10.2 KRT10 KRT17
45 large cell neuroendocrine carcinoma 10.1 KRT20 KRT7
46 immune system organ benign neoplasm 10.1 KRT20 KRT7
47 small intestine cancer 10.1 KRT20 KRT7
48 cervical adenoma malignum 10.1 KRT7 MME
49 thymus lipoma 10.1 KRT20 KRT7
50 cecum adenocarcinoma 10.1 KRT20 KRT7

Graphical network of the top 20 diseases related to Eccrine Sweat Gland Neoplasm:



Diseases related to Eccrine Sweat Gland Neoplasm

Symptoms & Phenotypes for Eccrine Sweat Gland Neoplasm

Drugs & Therapeutics for Eccrine Sweat Gland Neoplasm

Search Clinical Trials , NIH Clinical Center for Eccrine Sweat Gland Neoplasm

Genetic Tests for Eccrine Sweat Gland Neoplasm

Anatomical Context for Eccrine Sweat Gland Neoplasm

MalaCards organs/tissues related to Eccrine Sweat Gland Neoplasm:

41
Skin, Lung, Kidney, Breast, Ovary, Thymus, Appendix

Publications for Eccrine Sweat Gland Neoplasm

Articles related to Eccrine Sweat Gland Neoplasm:

# Title Authors Year
1
Benign chondroid syringoma: atypical presentation of a rare eccrine tumor. ( 21397527 )
2011

Variations for Eccrine Sweat Gland Neoplasm

Expression for Eccrine Sweat Gland Neoplasm

Search GEO for disease gene expression data for Eccrine Sweat Gland Neoplasm.

Pathways for Eccrine Sweat Gland Neoplasm

GO Terms for Eccrine Sweat Gland Neoplasm

Cellular components related to Eccrine Sweat Gland Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.43 KRT10 KRT15 KRT17 KRT5 KRT7 MME
2 intermediate filament GO:0005882 9.1 KRT10 KRT15 KRT17 KRT20 KRT5 KRT7

Biological processes related to Eccrine Sweat Gland Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytoskeleton organization GO:0007010 9.54 KRT15 KRT17 KRT5
2 keratinization GO:0031424 9.43 KRT10 KRT15 KRT17 KRT20 KRT5 KRT7
3 epidermis development GO:0008544 9.33 KRT15 KRT17 KRT5
4 intermediate filament organization GO:0045109 9.32 KRT17 KRT20
5 replicative senescence GO:0090399 9.26 MME TP53
6 cornification GO:0070268 9.1 KRT10 KRT15 KRT17 KRT20 KRT5 KRT7

Molecular functions related to Eccrine Sweat Gland Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural molecule activity GO:0005198 9.13 KRT10 KRT17 KRT7
2 structural constituent of cytoskeleton GO:0005200 8.92 KRT15 KRT17 KRT20 KRT5

Sources for Eccrine Sweat Gland Neoplasm

3 CDC
7 CNVD
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11 DGIdb
17 ExPASy
19 FMA
28 GO
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32 HPO
33 ICD10
34 ICD10 via Orphanet
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45 MESH via Orphanet
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49 NCI
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51 NDF-RT
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58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
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74 UMLS via Orphanet
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