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MCID: ECH002
MIFTS: 35

Echolalia

Categories: Mental diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for Echolalia

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MalaCards integrated aliases for Echolalia:

Name: Echolalia 12 43 15 71

Classifications:

MalaCards categories:
Anatomical: Mental diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:4188
MeSH 43 D004454
NCIt 49 C97166
SNOMED-CT 67 64712007
UMLS 71 C0013528
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Summaries for Echolalia

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Disease Ontology : 12 A speech disorder that involves the automatic repetition of vocalizations made by another person.

MalaCards based summary : Echolalia is related to gilles de la tourette syndrome and autism spectrum disorder, and has symptoms including photophobia, restlessness and scanning speech. An important gene associated with Echolalia is TOR3A (Torsin Family 3 Member A), and among its related pathways/superpathways are Neuroscience and Protein-protein interactions at synapses. The drug Anesthetics has been mentioned in the context of this disorder. Affiliated tissues include brain, cortex and liver.

Wikipedia : 74 Echolalia is the unsolicited repetition of vocalizations made by another person (when repeated by the... more...

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Related Diseases for Echolalia

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Diseases related to Echolalia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 77)
# Related Disease Score Top Affiliating Genes
1 gilles de la tourette syndrome 32.2 NRXN1 NLGN4X GTSCR1 CNTNAP2
2 autism spectrum disorder 30.9 NRXN1 NLGN4X NLGN3 MECP2 FOXP2 FMR1
3 aphasia 30.2 MAPT GRN FOXP2 C9orf72
4 supranuclear palsy, progressive, 1 29.9 MAPT GRN C9orf72
5 mutism 29.7 MAPT GRN FMR1 CNTNAP2 C9orf72
6 apraxia 29.5 MAPT GRN FOXP2 CNTNAP2 C9orf72
7 autism 29.1 NRXN1 NLGN4X NLGN3 MECP2 MAPT FOXP2
8 schizophrenia 28.3 NRXN1 NLGN4X MECP2 MAPT FOXP2 FMR1
9 chromosome 15q11-q13 duplication syndrome 11.2
10 frontotemporal dementia with parkinsonism-17 11.2
11 valproate embryopathy 10.2 NLGN3 MECP2
12 chromosome 16p13.3 deletion syndrome, proximal 10.2
13 pitt-hopkins-like syndrome 10.2 NRXN1 CNTNAP2
14 essential tremor 10.2 MAPT FMR1 C9orf72
15 frontotemporal lobar degeneration with tdp43 inclusions, grn-related 10.1 MAPT GRN
16 charcot-marie-tooth disease, axonal, type 2q 10.1 NLGN4X NLGN3 MECP2 FMR1
17 x-linked hereditary ataxia 10.1 FMR1 C9orf72
18 movement disease 10.1 MAPT FMR1 C9orf72
19 creutzfeldt-jakob disease 10.1
20 huntington disease 10.1
21 systemic lupus erythematosus 10.1
22 hyperlexia 10.1
23 chorea, childhood-onset, with psychomotor retardation 10.1
24 choreatic disease 10.1
25 mitral valve stenosis 10.1
26 status epilepticus 10.1
27 encephalomalacia 10.1
28 astrocytoma 10.1
29 germinoma 10.1
30 peripheral nervous system disease 10.1
31 neuropathy 10.1
32 lupus erythematosus 10.1
33 gait apraxia 10.1 MECP2 GRN
34 ideomotor apraxia 10.0 MAPT GRN
35 visual agnosia 10.0 MAPT GRN
36 associative agnosia 10.0 MAPT GRN C9orf72
37 progressive non-fluent aphasia 10.0 MAPT GRN C9orf72
38 semantic dementia 10.0 MAPT GRN C9orf72
39 agraphia 10.0 MAPT GRN C9orf72
40 nominal aphasia 10.0 MAPT GRN C9orf72
41 dysgraphia 10.0 MAPT GRN C9orf72
42 alexia 10.0 MAPT GRN
43 prosopagnosia 10.0 MAPT GRN C9orf72
44 writing disorder 10.0 MAPT GRN C9orf72
45 perry syndrome 10.0 MAPT GRN C9orf72
46 frontotemporal dementia and/or amyotrophic lateral sclerosis 1 9.9 MAPT GRN C9orf72
47 pitt-hopkins syndrome 9.9 NRXN1 MECP2 CNTNAP2
48 lubs x-linked mental retardation syndrome 9.9 MECP2 FMR1
49 chromosomal deletion syndrome 9.9 NRXN1 MECP2 FMR1
50 aceruloplasminemia 9.9 MAPT FMR1 CNTNAP2 C9orf72

Graphical network of the top 20 diseases related to Echolalia:



Diseases related to Echolalia
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Symptoms & Phenotypes for Echolalia

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UMLS symptoms related to Echolalia:


photophobia, restlessness, scanning speech, personality changes, pseudobulbar behavioral symptoms, sleep disturbances, other symbolic dysfunction, mental and behavioral signs and symptoms
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Drugs & Therapeutics for Echolalia

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Drugs for Echolalia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Anesthetics

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Assessment Effects of Somatosensorial and Vestibular Rehabilitation Additional Conventional Therapy on Balance in Patients With Acute Stroke Completed NCT03477188
2 Prospective Treatment Study of Catatonia Patients With Right Unilateral Electroconvulsive Treatment (RUL ECT) and Bilateral Electroconvulsive Treatment (BL ECT) Regimens Terminated NCT02734498

Search NIH Clinical Center for Echolalia

Cochrane evidence based reviews: echolalia

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Genetic Tests for Echolalia

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Anatomical Context for Echolalia

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MalaCards organs/tissues related to Echolalia:

40
Brain, Cortex, Liver, Cingulate Cortex
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Publications for Echolalia

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Articles related to Echolalia:

(show top 50) (show all 251)
# Title Authors PMID Year
1
The Influence of Language Context on Repetitive Speech Use in Children With Autism Spectrum Disorder. 61
32004083 2020
2
Echolalia. 61
31905078 2020
3
Catatonia with GABAA receptor antibodies. 61
31771952 2019
4
A case report on crossed aphasia in dextrals: Consideration about clinical features and neural network. 61
31651891 2019
5
Elevated mirror neuron system activity in bipolar mania: Evidence from a transcranial magnetic stimulation study. 61
30422373 2019
6
Improvement of Post Stroke Echolalia after Using Selective Serotonin Reuptake Inhibitors. 61
31097970 2019
7
Repetitive verbal behaviors are not always harmful signs: Compensatory plasticity within the language network in aphasia. 61
30665003 2019
8
Gogi (Word Meaning) Aphasia and Its Relation with Semantic Dementia. 61
31220829 2019
9
Language as a Threat: Multimodal Evaluation and Interventions for Overwhelming Linguistic Anxiety in Severe Aphasia. 61
31133908 2019
10
Two Sides of the Same Coin: A Case Report of First-Episode Catatonic Syndrome in a High-Functioning Autism Patient. 61
31031660 2019
11
Focal Electrographic Seizures in a Patient With Autism Spectrum Disorder and Speech Delay. 61
30461592 2018
12
Being vs. Appearing Socially Uninterested: Challenging Assumptions about Social Motivation in Autism. 61
29914590 2018
13
Frontotemporal lobar degeneration due to P301L tau mutation showing apathy and severe frontal atrophy but lacking other behavioral changes: A case report and literature review. 61
29105852 2018
14
Catatonia Under-Diagnosis in the General Hospital. 61
29325478 2018
15
Pali and Echo Phenomena: Symptoms of Persistence and Perseveration. 61
29145181 2018
16
Autism spectrum disorders and disease modeling using stem cells. 61
28918504 2018
17
Jumping Frenchmen, Miryachit, and Latah: Culture-Specific Hyperstartle-Plus Syndromes. 61
29151096 2018
18
Non-Neurogenic Language Disorders: A Preliminary Classification. 61
28911819 2018
19
Intermittent catatonia and complex automatisms caused by frontal lobe epilepsy in dementia. 61
29237665 2017
20
A Neural Basis for Contagious Yawning. 61
28867202 2017
21
[German version of the Northoff catatonia rating scale (NCRS-dv) : A validated instrument for measuring catatonic symptoms]. 61
27325247 2017
22
Association between speech-language, general cognitive functioning and behaviour problems in individuals with Williams syndrome. 61
28612476 2017
23
Sign Language Echolalia in Deaf Children With Autism Spectrum Disorder. 61
28586822 2017
24
Identification of Two Heritable Cross-Disorder Endophenotypes for Tourette Syndrome. 61
27809572 2017
25
Posterior fossa syndrome with a large inflammatory ponto-mesencephalic lesion. 61
27842285 2017
26
Hashimoto's Encephalopathy Presenting with Unusual Behavioural Disturbances in an Adolescent Girl. 61
28607558 2017
27
Thinking on Treating Echolalia in Aphasia: Recommendations and Caveats for Future Research Directions. 61
28420974 2017
28
Unusual psychotic presentation after discontinuation of treatment in a patient with Wilson's disease: a case report. 61
27996315 2016
29
Validation of the Pediatric Catatonia Rating Scale (PCRS). 61
27377978 2016
30
PSP-CBS with Dopamine Deficiency in a Female with a FMR1 Premutation. 61
27230899 2016
31
A Multidimensional Reappraisal of Language in Autism: Insights from a Discourse Analytic Study. 61
26701673 2016
32
Language and Speech in Autism. 61
28127576 2016
33
[Catatonia is often overlooked in child and adolescent psychiatry]. 61
26750196 2016
34
Catatonia in Ugandan children with nodding syndrome and effects of treatment with lorazepam: a pilot study. 61
26710961 2015
35
Non-convulsive status epilepticus: a practical approach to diagnosis in confused older people. 61
26399267 2015
36
Examining the Echolalia Literature: Where Do Speech-Language Pathologists Stand? 61
26161804 2015
37
Gilles de la Tourette syndrome in a cohort of deaf people. 61
26216703 2015
38
[Echolalia and progressive supranuclear palsy, an unexpected association]. 61
26178519 2015
39
[Catatonia]. 61
25858694 2015
40
Acute Psychosis after Recent Isoniazid Initiation. 61
26266198 2015
41
Are there distinct subtypes in Tourette syndrome? Pure-Tourette syndrome versus Tourette syndrome-plus, and simple versus complex tics. 61
26089672 2015
42
The role of β3 integrin gene variants in Autism Spectrum Disorders--diagnosis and symptomatology. 61
25280596 2014
43
Acute toxicity associated with the recreational use of the novel dissociative psychoactive substance methoxphenidine. 61
25350467 2014
44
Preliminary findings of similarities and differences in the signed and spoken language of children with autism. 61
25321855 2014
45
[Introduction and transformation of the psychiatric term "anancasm". From Gyula (Julius) Donáth via Kurt Schneider to ICD-10]. 61
24036702 2014
46
Electroconvulsive therapy for catatonia in juvenile neuropsychiatric lupus. 61
24786782 2014
47
Rethinking echolalia: repetition as interactional resource in the communication of a child with autism. 61
23469804 2014
48
Catatonia in patients with autism: prevalence and management. 61
24504828 2014
49
Anti-N-methyl-D-aspartate receptor-mediated encephalitis in infants and toddlers: case report and review of the literature. 61
24315538 2014
50
Echothymia: environmental dependency in the affective domain. 61
24515681 2014
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Variations for Echolalia

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Expression for Echolalia

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Search GEO for disease gene expression data for Echolalia.
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Pathways for Echolalia

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Pathways related to Echolalia according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Neuroscience 4
11.79 MECP2 MAPT FMR1 CNTNAP2
2
Protein-protein interactions at synapses 65
Show member pathways
 11.45 NRXN1 NLGN4X NLGN3
3
Cell adhesion molecules (CAMs) 36
11.09 NRXN1 NLGN4X NLGN3 CNTNAP2
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GO Terms for Echolalia

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Cellular components related to Echolalia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 dendrite GO:0030425 9.77 NLGN4X MAPT FMR1 CNTNAP2 C9orf72
2 postsynapse GO:0098794 9.63 NLGN3 MECP2 FMR1
3 axolemma GO:0030673 9.43 MAPT CNTNAP2
4 glial cell projection GO:0097386 9.4 MAPT FMR1
5 spanning component of membrane GO:0089717 9.32 NLGN4X NLGN3
6 main axon GO:0044304 9.26 MAPT C9orf72
7 presynapse GO:0098793 9.26 NRXN1 NLGN4X NLGN3 FMR1
8 asymmetric, glutamatergic, excitatory synapse GO:0098985 9.16 NLGN4X NLGN3
9 symmetric, GABA-ergic, inhibitory synapse GO:0098983 8.62 NLGN4X NLGN3

Biological processes related to Echolalia according to GeneCards Suite gene sharing:

(show all 18)
# Name GO ID Score Top Affiliating Genes
1 neuron projection development GO:0031175 9.76 NRXN1 MECP2 MAPT CNTNAP2
2 synapse assembly GO:0007416 9.69 NRXN1 NLGN3 MECP2
3 cerebellum development GO:0021549 9.67 NLGN4X MECP2 FOXP2
4 synapse organization GO:0050808 9.65 NLGN4X NLGN3 MAPT
5 neuron cell-cell adhesion GO:0007158 9.61 NRXN1 NLGN4X NLGN3
6 regulation of AMPA receptor activity GO:2000311 9.58 NRXN1 NLGN3
7 presynaptic membrane assembly GO:0097105 9.58 NRXN1 NLGN4X NLGN3
8 positive regulation of synaptic transmission, glutamatergic GO:0051968 9.57 NRXN1 NLGN3
9 stress granule assembly GO:0034063 9.56 MAPT C9orf72
10 adult behavior GO:0030534 9.56 NRXN1 NLGN4X NLGN3 CNTNAP2
11 presynapse assembly GO:0099054 9.55 NLGN4X NLGN3
12 learning GO:0007612 9.55 NRXN1 NLGN4X NLGN3 MECP2 CNTNAP2
13 regulation of respiratory gaseous exchange by neurological system process GO:0002087 9.54 NLGN3 MECP2
14 postsynaptic membrane assembly GO:0097104 9.54 NRXN1 NLGN4X NLGN3
15 negative regulation of excitatory postsynaptic potential GO:0090394 9.52 NLGN4X NLGN3
16 vocal learning GO:0042297 9.5 NRXN1 FOXP2 CNTNAP2
17 social behavior GO:0035176 9.35 NRXN1 NLGN4X NLGN3 MECP2 CNTNAP2
18 vocalization behavior GO:0071625 8.92 NRXN1 NLGN4X NLGN3 CNTNAP2

Molecular functions related to Echolalia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neurexin family protein binding GO:0042043 9.16 NLGN4X NLGN3
2 siRNA binding GO:0035197 8.96 MECP2 FMR1
3 cell adhesion molecule binding GO:0050839 8.8 NRXN1 NLGN4X NLGN3
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Sources for Echolalia

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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