Aliases & Classifications for Echolalia

MalaCards integrated aliases for Echolalia:

Name: Echolalia 12 29 44 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:4188
MeSH 44 D004454
NCIt 50 C97166
SNOMED-CT 68 64712007
UMLS 73 C0013528

Summaries for Echolalia

Disease Ontology : 12 A speech disorder that involves the automatic repetition of vocalizations made by another person.

MalaCards based summary : Echolalia is related to aphasia and gilles de la tourette syndrome, and has symptoms including photophobia, restlessness and scanning speech. An important gene associated with Echolalia is GRN (Granulin Precursor). The drugs Verapamil and Calcium, Dietary have been mentioned in the context of this disorder. Affiliated tissues include cortex, liver and brain, and related phenotypes are behavior/neurological and cellular

Wikipedia : 76 Echolalia (also known as echologia or echophrasia) is defined as the unsolicited repetition of... more...

Related Diseases for Echolalia

Diseases related to Echolalia via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 42)
# Related Disease Score Top Affiliating Genes
1 aphasia 30.4 GRN MAPT PSEN1
2 gilles de la tourette syndrome 11.6
3 autism 10.4
4 phonagnosia 10.2 GRN PSEN1
5 frontotemporal lobar degeneration with tdp43 inclusions, grn-related 10.2 GRN MAPT
6 associative agnosia 10.2 GRN PSEN1
7 writing disorder 10.2 GRN PSEN1
8 prosopagnosia 10.2 GRN PSEN1
9 pedophilia 10.1 GRN IRGC
10 ideomotor apraxia 10.1 CBS GRN MAPT
11 familial idiopathic basal ganglia calcification 10.1 MAPT PSEN1
12 chromosome 16p13.3 deletion syndrome, proximal 10.1
13 kohlschutter-tonz syndrome 10.1 MAPT PSEN1
14 frontotemporal dementia 10.1 GRN MAPT PSEN1
15 nominal aphasia 10.1 GRN MAPT PSEN1
16 apraxia 10.1 GRN MAPT PSEN1
17 gait apraxia 10.1 CBS GRN PSEN1
18 progressive non-fluent aphasia 10.1 GRN MAPT PSEN1
19 behavioral variant of frontotemporal dementia 10.1 GRN MAPT PSEN1
20 exhibitionism 10.1 ADD2 CBS
21 visual agnosia 10.1 GRN PSEN1
22 semantic dementia 10.1 GRN MAPT PSEN1
23 kluver-bucy syndrome 10.1 MAPT PSEN1
24 pick disease of brain 10.1 GRN MAPT PSEN1
25 specific developmental disorder 10.1 FMR1 GRN PSEN1
26 alzheimer disease 2 10.0 MAPT PSEN1
27 agraphia 10.0 CBS GRN MAPT PSEN1
28 frontotemporal dementia and/or amyotrophic lateral sclerosis 1 10.0 CBS GRN MAPT PSEN1
29 supranuclear palsy, progressive, 1 10.0 CBS GRN MAPT PSEN1
30 dementia, lewy body 10.0 CBS GRN MAPT PSEN1
31 speech and communication disorders 10.0 CBS GRN MAPT PSEN1
32 disease of mental health 10.0 FMR1 GRN MAPT PSEN1
33 creutzfeldt-jakob disease 10.0
34 systemic lupus erythematosus 10.0
35 hyperlexia 10.0
36 stroke, ischemic 10.0
37 autism spectrum disorder 10.0
38 status epilepticus 10.0
39 epilepsy 10.0
40 lupus erythematosus 10.0
41 paraphilia disorder 10.0 ADD2 CBS GRN IRGC
42 von willebrand disease, type 2 9.9 ENSG00000259753 ITGB3

Graphical network of the top 20 diseases related to Echolalia:



Diseases related to Echolalia

Symptoms & Phenotypes for Echolalia

UMLS symptoms related to Echolalia:


photophobia, restlessness, scanning speech, personality changes, pseudobulbar behavioral symptoms, sleep disturbances, other symbolic dysfunction, mental and behavioral signs and symptoms

MGI Mouse Phenotypes related to Echolalia:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.97 ADD2 BHLHE22 FMR1 GRN IKBKG LGALS1
2 cellular MP:0005384 9.92 BHLHE22 DUSP4 FMR1 GRN IKBKG ITGB3
3 immune system MP:0005387 9.86 ADD2 DUSP4 GRN IKBKG ITGB3 LGALS1
4 integument MP:0010771 9.7 BHLHE22 FMR1 IKBKG ITGB3 LGALS1 MAPT
5 nervous system MP:0003631 9.56 ADD2 BHLHE22 FMR1 GRN ITGB3 LGALS1
6 vision/eye MP:0005391 9.1 BHLHE22 FMR1 GRN ITGB3 MAPT PSEN1

Drugs & Therapeutics for Echolalia

Drugs for Echolalia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Verapamil Approved Phase 2 52-53-9 2520
2 Calcium, Dietary Phase 2
3 Vasodilator Agents Phase 2
4 Anti-Arrhythmia Agents Phase 2
5 calcium channel blockers Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Sapropterin as a Treatment for Autistic Disorder Completed NCT00850070 Phase 2 sapropterin;Placebo

Search NIH Clinical Center for Echolalia

Cochrane evidence based reviews: echolalia

Genetic Tests for Echolalia

Genetic tests related to Echolalia:

# Genetic test Affiliating Genes
1 Echolalia 29

Anatomical Context for Echolalia

MalaCards organs/tissues related to Echolalia:

41
Cortex, Liver, Brain, Cingulate Cortex

Publications for Echolalia

Articles related to Echolalia:

(show top 50) (show all 56)
# Title Authors Year
1
Sign Language Echolalia in Deaf Children With Autism Spectrum Disorder. ( 28586822 )
2017
2
Thinking on Treating Echolalia in Aphasia: Recommendations and Caveats for Future Research Directions. ( 28420974 )
2017
3
Examining the Echolalia Literature: Where Do Speech-Language Pathologists Stand? ( 26161804 )
2015
4
Rethinking echolalia: repetition as interactional resource in the communication of a child with autism. ( 23469804 )
2013
5
On the differential nature of induced and incidental echolalia in autism. ( 22676294 )
2013
6
The pathophysiology of echopraxia/echolalia: relevance to Gilles de la Tourette syndrome. ( 22807284 )
2012
7
Ambient echolalia in a patient with germinoma around the bilateral ventriculus lateralis: a case report. ( 22117108 )
2012
8
Echolalia or functional repetition in conversation--a case study of an individual with Huntington's disease. ( 20831380 )
2011
9
Echocardiographic investigations of myocardial function in mitral stenosis: making sense of the echolalia. ( 21952160 )
2011
10
Verbal repetitions and echolalia in Alzheimer's discourse. ( 20964503 )
2010
11
Echolalia in the language development of autistic individuals: a bibliographical review. ( 19838574 )
2009
12
Hyperlexia and ambient echolalia in a case of cerebral infarction of the left anterior cingulate cortex and corpus callosum. ( 19585352 )
2009
13
Palilalia, echolalia, and echopraxia-palipraxia as ictal manifestations in a patient with left frontal lobe epilepsy. ( 19175395 )
2009
14
The emergence of echolalia while taking sertraline in a patient with Tourette's syndrome. ( 18481372 )
2008
15
Postoperative echolalia and catatonia responsive to gamma aminobutyric acid receptor agonists in a liver transplant patient. ( 16931705 )
2006
16
Chronic 'speech catatonia' with constant logorrhea, verbigeration and echolalia successfully treated with lorazepam: a case report. ( 15601393 )
2004
17
Echolalia in a liver transplant recipient. ( 15316384 )
2004
18
Prominent echolalia from isolation of the speech area. ( 12154164 )
2002
19
Echolalia as a novel manifestation of neuropsychiatric systemic lupus erythematosus. ( 11213948 )
2001
20
Echolalia-palilalia as the sole manifestation of nonconvulsive status epilepticus. ( 10980752 )
2000
21
Effortful echolalia. ( 9533994 )
1998
22
Study of a nervous disorder characterized by motor incoordination with echolalia and coprolalia (The introduction and case studies of Gilles de la Tourette's 1885 paper). ( 11620011 )
1998
23
Brief report: treatment of echolalia in a girl with Rubinstein-Taybi syndrome: functional assessment of minimizing chances to provoke echolalia. ( 9932244 )
1998
24
Teaching receptive naming of Chinese characters to children with autism by incorporating echolalia. ( 9157099 )
1997
25
Effects of high and low constraint utterances on the production of immediate and delayed echolalia in young children with autism. ( 7844096 )
1994
26
Creutzfeldt-Jakob disease with mixed transcortical aphasia: insights into echolalia. ( 24487337 )
1994
27
Evolution of technetium-99m-HMPAO SPECT and brain mapping in a patient presenting with echolalia and palilalia. ( 1869990 )
1991
28
The effects of two levels of linguistic constraint on echolalia and generative language production in children with autism. ( 1864826 )
1991
29
Long-term follow-up of echolalia and question answering. ( 2249974 )
1990
30
Echolalia and comprehension in autistic children. ( 2745392 )
1989
31
The functions of immediate echolalia in autistic children: a developmental perspective. ( 3215891 )
1988
32
Setting effects on the occurrence of autistic children's immediate echolalia. ( 3804960 )
1986
33
Some direct and generalized effects of replacing an autistic man's echolalia with correct responses to questions. ( 3771422 )
1986
34
Immediate echolalia and the interactive behaviour of autistic children. ( 3832444 )
1985
35
Analysis of functions of delayed echolalia in autistic children. ( 6738028 )
1984
36
The effects of echolalia on acquisition and generalization of receptive labeling in autistic children. ( 6833164 )
1983
37
Medical writing: Echolalia. ( 7152728 )
1982
38
Language processing and forms of immediate echolalia in autistic children. ( 7087424 )
1982
39
The functions of immediate echolalia in autistic children. ( 7278167 )
1981
40
Delayed echolalia in autism: some observations on differences within the term. ( 7326840 )
1981
41
Response sets in autistic echolalia. ( 7290887 )
1981
42
Echolalia: issues and clinical applications. ( 390245 )
1979
43
Social and attentional aspects of echolalia in highly echolalic mentally retarded persons. ( 623163 )
1978
44
Control of selective echolalia via the instatement of a general alternative response. ( 718598 )
1978
45
Late onset echolalia in autism and allied disorders. ( 857834 )
1977
46
[Transcortical aphasia and echolalia; problems of speech initiative]. ( 1188237 )
1975
47
Semantic considerations in the treatment of echolalia. ( 1177772 )
1975
48
On some language parameters of autistic echolalia. ( 4459628 )
1974
49
On the echolalia of the blind and of the autistic child. ( 4754881 )
1973
50
On echolalia, echo-answer, and contamination. ( 5001522 )
1971

Variations for Echolalia

Expression for Echolalia

Search GEO for disease gene expression data for Echolalia.

Pathways for Echolalia

GO Terms for Echolalia

Cellular components related to Echolalia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 integrin complex GO:0008305 9.16 ENSG00000259753 ITGB3
2 growth cone GO:0030426 9.13 FMR1 MAPT PSEN1
3 glial cell projection GO:0097386 8.62 FMR1 MAPT

Biological processes related to Echolalia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of protein phosphorylation GO:0001934 9.43 FMR1 ITGB3 PSEN1
2 positive regulation of dendritic spine development GO:0060999 9.16 FMR1 PSEN1
3 cell adhesion mediated by integrin GO:0033627 8.96 ENSG00000259753 ITGB3
4 astrocyte activation GO:0048143 8.62 MAPT PSEN1

Molecular functions related to Echolalia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.35 CBS FMR1 IKBKG ITGB3 MAPT
2 protein homodimerization activity GO:0042803 9.1 ADD2 CBS FMR1 IKBKG LGALS1 MAPT

Sources for Echolalia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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