MCID: ECL001
MIFTS: 57

Eclampsia

Categories: Rare diseases, Cardiovascular diseases, Reproductive diseases

Aliases & Classifications for Eclampsia

MalaCards integrated aliases for Eclampsia:

Name: Eclampsia 12 53 29 55 44 15 73
Eclampsia in Puerperium 12 73
Eclampsia, Postpartum 12
Postpartum Eclampsia 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13593
ICD10 33 O15 O15.9 O15.2
MeSH 44 D004461
NCIt 50 C87167

Summaries for Eclampsia

Disease Ontology : 12 A pre-eclampsia characterized by the presence of seizures.

MalaCards based summary : Eclampsia, also known as eclampsia in puerperium, is related to severe pre-eclampsia and placental insufficiency, and has symptoms including seizures An important gene associated with Eclampsia is STOX1 (Storkhead Box 1), and among its related pathways/superpathways are VEGF ligand-receptor interactions and Warfarin Pathway, Pharmacodynamics. The drugs Methyldopa and Calcium Carbonate have been mentioned in the context of this disorder. Affiliated tissues include endothelial, placenta and testes, and related phenotypes are cardiovascular system and growth/size/body region

Wikipedia : 76 Eclampsia is the onset of seizures (convulsions) in a woman with pre-eclampsia. Pre-eclampsia is a... more...

Related Diseases for Eclampsia

Diseases in the Eclampsia family:

Pre-Eclampsia Severe Pre-Eclampsia

Diseases related to Eclampsia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 225)
# Related Disease Score Top Affiliating Genes
1 severe pre-eclampsia 32.3 ALB HLA-G LGALS13 PGF SERPINC1
2 placental insufficiency 30.8 F2 FLT1 PGF
3 microvascular complications of diabetes 5 30.0 ALB FLT1 PGF
4 placenta disease 29.7 MTHFR OXT PGF SERPINC1
5 hepatorenal syndrome 29.3 ALB EDN1 F2
6 antithrombin iii deficiency 29.0 F2 MTHFR SERPINC1
7 central retinal vein occlusion 29.0 F2 MTHFR SERPINC1
8 portal vein thrombosis 29.0 F2 MTHFR SERPINC1
9 retinal vein occlusion 29.0 F2 MTHFR SERPINC1
10 pulmonary edema 28.8 EDN1 F2 SERPINC1
11 thrombophilia 28.8 F2 MTHFR SERPINC1 THBD
12 antiphospholipid syndrome 28.8 F2 MTHFR SERPINC1 THBD
13 purpura 28.5 F2 SERPINC1 THBD
14 hellp syndrome 28.5 EDN1 ENG F2 FLT1 LGALS13 MTHFR
15 thrombosis 28.2 F2 MTHFR SERPINC1 THBD
16 placental abruption 27.9 ENG F2 FLT1 MTHFR PGF SERPINC1
17 heart disease 27.5 ALB EDN1 F2 MTHFR SERPINC1
18 vascular disease 26.6 ALB EDN1 ENG F2 MTHFR SERPINC1
19 myocardial infarction 25.9 ALB EDN1 ENG F2 MTHFR PGF
20 pre-eclampsia 25.9 C19orf33 CORIN EDN1 ENG EPHX1 F2
21 preeclampsia/eclampsia 5 12.4
22 preeclampsia/eclampsia 4 12.4
23 mild pre-eclampsia 12.3
24 preeclampsia/eclampsia 1 12.1
25 preeclampsia/eclampsia 2 11.9
26 preeclampsia/eclampsia 3 11.9
27 gestational diabetes 11.3
28 chorea gravidarum 10.9
29 glomeruloid hemangioma 10.8 ENG FLT1
30 twin-to-twin transfusion syndrome 10.8 ENG FLT1 PGF
31 mesenteric vascular occlusion 10.6 F2 MTHFR
32 antipyrine metabolism 10.6 ALB F2
33 livedoid vasculopathy 10.6 F2 MTHFR
34 non-a-e hepatitis 10.6 ALB F2
35 endotheliitis 10.5
36 ischemic neuropathy 10.5 F2 MTHFR
37 retinal vascular disease 10.5 ALB FLT1 MTHFR
38 abdominal tuberculosis 10.4 ALB F2
39 parametritis 10.3 F2 OXT
40 nutritional deficiency disease 10.3 ALB F2 MTHFR
41 uterine anomalies 10.3 MTHFR OXT PGF
42 chronic thromboembolic pulmonary hypertension 10.3 EDN1 F2
43 aging 10.2
44 kwashiorkor 10.2 ALB F2
45 cerebritis 10.2
46 hypoxia 10.2
47 encephalopathy 10.2
48 cortical blindness 10.1
49 hepatic tuberculosis 10.1 ALB F2
50 retinitis 10.1

Graphical network of the top 20 diseases related to Eclampsia:



Diseases related to Eclampsia

Symptoms & Phenotypes for Eclampsia

UMLS symptoms related to Eclampsia:


seizures

MGI Mouse Phenotypes related to Eclampsia:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.02 CORIN EDN1 ENG F2 FLT1 NOSTRIN
2 growth/size/body region MP:0005378 9.9 CORIN EDN1 ENG F2 FLT1 INHBB
3 digestive/alimentary MP:0005381 9.86 ALB EDN1 ENG F2 INHBB OXT
4 homeostasis/metabolism MP:0005376 9.83 TAC3 THBD ALB CORIN EDN1 ENG
5 integument MP:0010771 9.23 CORIN ENG F2 INHBB MTHFR OXT

Drugs & Therapeutics for Eclampsia

Drugs for Eclampsia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 392)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Methyldopa Approved Phase 4,Phase 2,Phase 1,Not Applicable 555-30-6 38853
2
Calcium Carbonate Approved, Investigational Phase 4,Not Applicable 471-34-1
3
Remifentanil Approved Phase 4,Phase 2 132875-61-7 60815
4
Amlodipine Approved Phase 4 88150-42-9 2162
5
Metformin Approved Phase 4,Phase 3,Phase 2,Not Applicable 657-24-9 14219 4091
6
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 50-78-2 2244
7
Dalteparin Approved Phase 4,Phase 2,Phase 3 9005-49-6
8
Enoxaparin Approved Phase 4,Phase 3,Not Applicable 9005-49-6 772
9
Heparin Approved, Investigational Phase 4,Phase 2,Phase 3 9005-49-6 772 46507594
10
Bupivacaine Approved, Investigational Phase 4,Phase 3,Not Applicable 2180-92-9, 38396-39-3 2474
11
Zinc Approved, Investigational Phase 4,Phase 2,Phase 3,Not Applicable 7440-66-6 23994
12
Ephedrine Approved Phase 4,Phase 3,Not Applicable 299-42-3 9294
13
Oxymetazoline Approved, Investigational Phase 4,Not Applicable 1491-59-4 4636
14
Phenylephrine Approved Phase 4,Not Applicable 59-42-7 6041
15
Pseudoephedrine Approved Phase 4,Phase 3,Not Applicable 90-82-4 7028
16
Labetalol Approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 36894-69-6 3869
17
Oxytocin Approved, Vet_approved Phase 4,Phase 3,Not Applicable,Early Phase 1 50-56-6 439302 53477758
18
Magnesium Sulfate Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 7487-88-9 24083
19
Rocuronium Approved Phase 4 119302-91-9, 143558-00-3 441290
20
Acetaminophen Approved Phase 4,Phase 2,Phase 3 103-90-2 1983
21
Ibuprofen Approved Phase 4,Phase 2,Phase 3 15687-27-1 3672
22
Furosemide Approved, Vet_approved Phase 4 54-31-9 3440
23
Levobupivacaine Approved, Investigational Phase 4 27262-47-1 92253
24
Captopril Approved Phase 4 62571-86-2 44093
25
Clonidine Approved Phase 4,Phase 1,Phase 2,Not Applicable 4205-90-7 2803
26
Insulin Aspart Approved Phase 4,Phase 3 116094-23-6 16132418
27
Insulin Lispro Approved Phase 4 133107-64-9
28
Nifedipine Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1 21829-25-4 4485
29
Azithromycin Approved Phase 4,Phase 3 83905-01-5 55185 447043
30
Benzocaine Approved, Investigational Phase 4,Phase 3 1994-09-7, 94-09-7 2337
31
Desogestrel Approved Phase 4 54024-22-5 40973
32
Etonogestrel Approved, Investigational Phase 4 54048-10-1 40976 6917715
33
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 59-30-3 6037
34
leucovorin Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Not Applicable 58-05-9 143 6006
35
Ergocalciferol Approved, Nutraceutical Phase 4,Phase 1,Phase 2,Not Applicable 50-14-6 5280793
36
Vitamin D Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 1406-16-2
37
Vitamin D3 Approved, Nutraceutical Phase 4,Phase 1,Phase 2,Not Applicable 67-97-0 6221 5280795
38
Serine Approved, Nutraceutical Phase 4,Phase 3 56-45-1 5951
39 tannic acid Approved, Nutraceutical Phase 4,Phase 3
40 Antihypertensive Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
41 Adrenergic Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
42 Adrenergic Agonists Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
43 Adrenergic alpha-2 Receptor Agonists Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
44 Adrenergic alpha-Agonists Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
45 Autonomic Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1
46 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
47 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
48 Sympatholytics Phase 4,Phase 2,Phase 1,Early Phase 1,Not Applicable
49 Bone Density Conservation Agents Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
50 Calcium, Dietary Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1

Interventional clinical trials:

(show top 50) (show all 521)
# Name Status NCT ID Phase Drugs
1 Anti-Hypertensive Treatment In Stable Pregnant Women With Severe Pre-Eclampsia (Metildopape) Unknown status NCT01361425 Phase 4 methildopa;placebo
2 Cardiovascular and Autonomic Reactivity in Women With a History of Pre-eclampsia Unknown status NCT00117546 Phase 4 alpha methyldopa
3 Low Dose Calcium to Prevent Preeclampsia Unknown status NCT02338687 Phase 4
4 Remifentanil for General Anesthesia in Preeclamptics Unknown status NCT00567957 Phase 4 Remifentanil;Saline
5 Pharmacokinetics of Amlodipine Besylate at Delivery and During Lactation Unknown status NCT02353806 Phase 4 Amlodipine besylate
6 Metformin and Gestational Diabetes in High-risk Patients: a RCTs Unknown status NCT00883259 Phase 4 Metformin
7 Prevention of Pre-eclampsia and SGA by Low-Dose Aspirin in Nulliparous Women With Abnormal First-trimester Uterine Artery Dopplers Completed NCT01729468 Phase 4 Aspirin;Placebo
8 Effects of Magnesium Sulphate on Sugammadex Reversal of Rocuronium Induced Blockade in Gynaecology Patients Completed NCT01972659 Phase 4 placebo;Magnesium Sulphate;sugammadex
9 The Effect of Ibuprofen on Post-partum Blood Pressure in Women With Hypertensive Disorders of Pregnancy Completed NCT02891174 Phase 4 Ibuprofen;Acetaminophen
10 Diuretics for Postpartum High Blood Pressure in Preeclampsia Completed NCT02163655 Phase 4 FUROSEMIDE;Placebo
11 Treatment Approaches to Preeclampsia Completed NCT01030627 Phase 4
12 Effectiveness Study of Short Course of Magnesium Sulfate for Severe Preeclamsia Completed NCT01408979 Phase 4 Magnesium sulfate 12 hours;Magnesium sulfate 24 hours
13 Comparison of Doses of Acetylsalicylic Acid in Women With Previous History of Preeclampsia Completed NCT01352234 Phase 4 Acetylsalicylic Acid;Acetylsalicylic Acid
14 Low Molecular Weight Heparin in Recurrent Miscarriage With Negative Antiphospholipid Antibodies Completed NCT01608347 Phase 4 LMWH+Folic acid;Folic Acid
15 Adding MgSO4 to Epidural Levobupivacaine in CS for Patients With Preeclampsia Completed NCT02699827 Phase 4 Levobupivacaine hydrochloride;Magnesium sulphate;Saline 0.9%
16 A Trial Comparing Treatment With the Springfusor Infusion Pump to the IV Magnesium Sulfate Regimen Completed NCT02091401 Phase 4 Magnesium Sulfate
17 Clonidine Versus Captopril for Treatment of Postpartum Very High Blood Pressure Completed NCT01761916 Phase 4 CLONIDINE;CAPTOPRIL
18 Metformin Versus Insulin in Gestational Diabetes Completed NCT01240785 Phase 4 metformin;insulin
19 Efficacy of Corifollitropin Alfa Versus Follitropin Beta in Aged IVF (In-vitro Fertilization) Patients Completed NCT02466204 Phase 4 corifollitropin alfa;Follitropin Beta
20 Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' Boostrix™ Vaccine in Pregnant Women Completed NCT02377349 Phase 4 Saline placebo
21 Phenylephrine Versus Ephedrine in Pre-eclampsia Recruiting NCT02025426 Phase 4 Phenylephrine;Ephedrine
22 Efficacy and Safety of 1 g Vs 2 g Per Hour Intravenous Maintenance Dose of MgSO4 in Women With Severe Pre-eclampsia Recruiting NCT03164304 Phase 4 Magnesium Sulfate
23 Impact of Antichlamydial Treatment on the Rate of Preeclampsia Recruiting NCT03233880 Phase 4 Azithromycin 1gm
24 Early Vascular Adjustments During Hypertensive Pregnancy Recruiting NCT02531490 Phase 4 Labetalol;Nifedipine;Methyldopa
25 Oral Nifedipine Versus Labetalol in Treatment of Postpartum Hypertension Recruiting NCT03449277 Phase 4 Oral Tablet
26 A Randomized Control Trial of Vitamin D Prophylaxis in the Prevention of Hypertensive Disorders of Pregnancy Recruiting NCT02920593 Phase 4 Vitamin D3
27 Response to Anti-hypertensives in Pregnant and Postpartum Patients Recruiting NCT03506724 Phase 4 Nifedipine;Labetalol
28 Oral Antihypertensive Regimens for Management of Hypertension in Pregnancy Recruiting NCT01912677 Phase 4 Nifedipine;Labetalol;Methyldopa
29 Continued Versus Discontinued Oxytocin Stimulation of Labour Recruiting NCT02553226 Phase 4 Oxytocin;Placebo
30 Chronic Hypertension and Pregnancy (CHAP) Project Recruiting NCT02299414 Phase 4 Anti-hypertensive therapy
31 Effect of Acetaminophen on Postpartum Blood Pressure Control in Preeclampsia With Severe Features Active, not recruiting NCT02911701 Phase 4 Acetaminophen;Ibuprofen
32 Contraception in Women With Sickle Cell Disease Active, not recruiting NCT02594462 Phase 4 etonogestrel-releasing implant contraceptive
33 Discontinuation of Magnesium Sulfate After Delivery in Women With Severe Preeclampsia. A Randomized Controlled Trial Not yet recruiting NCT03318211 Phase 4 Magnesium Sulfate
34 Effect of Administering Intravenous Magnesium Sulfate on Fetal Cardiotocography and Neonatal Outcome in Preeclamptic Patients Not yet recruiting NCT03237000 Phase 4 MgSO4
35 Metformin for Preeclampsia Prevention in Pregnant Women With Type 1 Diabetes Mellitus Not yet recruiting NCT03570632 Phase 4 Metformin
36 Different Schemes of Magnesium Sulfate for Preeclampsia Terminated NCT02396030 Phase 4 Magnesium sulfate 50% - 1g/h;Magnesium sulfate 50% - 2g/h
37 Atenativ Effect on Uterine Blood Flow and Preeclampsia Withdrawn NCT02278575 Phase 4 Atenativ
38 Investigating the Novel Observation of Right-Left Difference in Uterine Artery Vascular Resistance in Pre-Eclampsia Unknown status NCT00848679 Phase 3 Epidural lidocaine;Epidural lidocaine 2%
39 Treatment of Severe Hypertension During Pre-Eclampsia: A Preliminary Equivalence Study Between Urapidil and Nicardipine Unknown status NCT00409253 Phase 3 URAPIDIL (EUPRESSYL*);NICARDIPINE
40 Randomized Clinical Trial of Labetalol Versus Hydralazine for Severe Hypertension in Obstetric Patients. Unknown status NCT02050529 Phase 2, Phase 3 Labetalol;Hydralazine
41 A Randomized Trial of Docosahexaenoic Acid Supplementation During Pregnancy to Prevent Deep Placentation Disorders Unknown status NCT02336243 Phase 3
42 Carbetocin vs. Oxytocin for Prevention of Postpartum Bleeding in Patients With Severe Preeclampsia Unknown status NCT01382732 Phase 3 Carbetocin;Oxytocin
43 A Randomized Clinical Trial of Oral Magnesium Supplementation in Pregnancy Unknown status NCT02032186 Phase 3 Magnesium citrate
44 Low Dose Aspirin for the Prevention of Preeclampsia Unknown status NCT01890005 Phase 3 Aspirin;Placebo
45 PP13 and Doppler Study to Predict Preeclampsia Unknown status NCT00928213 Phase 2, Phase 3 Progesterone;Low molecular weight Heparin;No Drug
46 Effect of Micronutrients and Exercise During Pregnancy on Factors Related With Non-Transmissible Chronic Diseases Unknown status NCT00872365 Phase 2, Phase 3
47 Folic Acid Dosage and Malformations Reduction Unknown status NCT01244347 Phase 3 folic acid;folic acid
48 New Magnesium Sulphate Protocol for Pre-eclampsia Completed NCT01846156 Phase 3 MgSO4
49 Antepartum Chronic Epidural Therapy (ACET) to Improve Blood Flow to the Uterus, Placenta and Baby in Pre-Eclampsia and Intrauterine Growth Restriction Completed NCT00197340 Phase 3 Epidural ropivacaine
50 Magnesium Sulfate in Pregnancy and Postpartum Completed NCT02317146 Phase 2, Phase 3 Magnesium Sulfate

Search NIH Clinical Center for Eclampsia

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: eclampsia

Genetic Tests for Eclampsia

Genetic tests related to Eclampsia:

# Genetic test Affiliating Genes
1 Eclampsia 29

Anatomical Context for Eclampsia

MalaCards organs/tissues related to Eclampsia:

41
Endothelial, Placenta, Testes, Kidney, Lung, Thyroid, Liver

Publications for Eclampsia

Articles related to Eclampsia:

(show top 50) (show all 1975)
# Title Authors Year
1
Is it time to move towards non-invasive prenatal screening for Down syndrome and screening for pre-eclampsia? ( 29446241 )
2018
2
Hemoglobin levels during the first trimester of pregnancy are associated with the risk of gestational diabetes mellitus, pre-eclampsia and preterm birth in Chinese women: a retrospective study. ( 29940874 )
2018
3
The feasibility of task-sharing the identification, emergency treatment, and referral for women with pre-eclampsia by community health workers in India. ( 29945662 )
2018
4
Maternal cardiac output response to colloid preload and vasopressor therapy during spinal anaesthesia for caesarean section in patients with severe pre-eclampsia: a randomised, controlled trial. ( 29086911 )
2018
5
Induction of systemic inflammation by hyaluronan and hsp70 in women with pre-eclampsia. ( 29438905 )
2018
6
Pre-Eclampsia and Eclampsia: An Update on the Pharmacological Treatment Applied in Portugal. ( 29367581 )
2018
7
Quality assessment of uterine artery Doppler measurement in first trimester combined screening for pre-eclampsia. ( 29917286 )
2018
8
Recurrence of pre-eclampsia and the risk of future hypertension and cardiovascular disease: a systematic review and meta-analysis. ( 29978553 )
2018
9
Screening for pre-eclampsia at 35-37 weeks' gestation. ( 29896778 )
2018
10
Elabela-APJ axis contributes to embryonic development and prevents pre-eclampsia in pregnancy. ( 29342224 )
2018
11
Decidual regulation of trophoblast is altered in pregnancies at risk of pre-eclampsia. ( 29437882 )
2018
12
Measurement of area difference ratio of Photoplethysmographic pulse wave in patients with pre-eclampsia. ( 29970018 )
2018
13
Streptococcus pyogenes subdural empyema and pre-eclampsia. ( 29582773 )
2018
14
Associations between the timing and dosing of aspirin prophylaxis and term and preterm pre-eclampsia. ( 29880699 )
2018
15
Associations of polymorphisms of CYP2D6 and CYP2C9 with early onset severe pre-eclampsia and response to labetalol therapy. ( 29789925 )
2018
16
A case of partial hydatidiform molar pregnancy with a placental diploid-triploid mosaicism associated with a euploid viable foetus complicated with severe pre-eclampsia. ( 29421928 )
2018
17
Up-regulation of miR-299 suppressed the invasion and migration of HTR-8/SVneo trophoblast cells partly via targeting HDAC2 in pre-eclampsia. ( 29145147 )
2018
18
Three-dimensional indices of renal perfusion in normal pregnancy and pre-eclampsia. ( 29916133 )
2018
19
A computerized algorithm to capture patient's past preeclampsia and eclampsia history from prenatal clinical notes. ( 29388496 )
2018
20
Combination of first trimester serum afamin levels and three-dimensional placental bed vascularization as a possible screening method to detect women at-risk for adverse pregnancy complications like pre-eclampsia and gestational diabetes mellitus in low-risk pregnancies. ( 29405972 )
2018
21
Study on the correlation between adipocyte fatty-acid binding protein, glucolipid metabolism, and pre-eclampsia. ( 29316087 )
2018
22
Utility of serology in the diagnosis of pre-eclampsia and haemolytic uraemic syndrome in pregnancy-related acute kidney injury. ( 29890047 )
2018
23
Screening for pre-eclampsia by maternal factors and biomarkers at 11-13a88weeks' gestation. ( 29896812 )
2018
24
Re: Placental histopathology associated with pre-eclampsia: a systematic review and meta-analysis. ( 29417682 )
2018
25
Prediction and prevention of pre-eclampsia in Asian subpopulation. ( 29442407 )
2018
26
HLA-DR is aberrantly expressed at feto-maternal interface in pre-eclampsia. ( 29941324 )
2018
27
Are women with history of pre-eclampsia starting a new pregnancy in good nutritional status in South Africa and Zimbabwe? ( 29907146 )
2018
28
Baseline check of blood pressure readings of an automated device in severe pre-eclampsia and healthy normotensive pregnancy. ( 29674198 )
2018
29
Association between fetal fraction on cell-free DNA testing and first trimester markers for pre-eclampsia. ( 29318732 )
2018
30
Effect of blood pressure on reversible posterior leukoencephalopathy syndrome in pre-eclampsia or eclampsia. ( 29093565 )
2018
31
Prediction of pre-eclampsia and its subtypes in high-risk cohort: hyperglycosylated human chorionic gonadotropin in multivariate models. ( 29970026 )
2018
32
Pre-eclampsia and the risk of autism-spectrum disorder in offspring: meta-analysis. ( 29436313 )
2018
33
Dexmedetomidine as a part of general anaesthesia for caesarean delivery in patients with pre-eclampsia: Efficacy and foetal outcome: a randomised double-blinded trial. ( 29432379 )
2018
34
The potential therapeutic effects of ergothioneine in pre-eclampsia. ( 29284116 )
2018
35
Int6/eIF3e Silencing Promotes Placenta Angiogenesis in a Rat Model of Pre-eclampsia. ( 29895936 )
2018
36
Serum amyloid A, procalcitonin, highly sensitive C reactive protein and tumor necrosis factor alpha levels and acute inflammatory response in patients with hemolysis, elevated liver enzymes, low platelet count (HELLP) and eclampsia. ( 29345041 )
2018
37
Molar pregnancy with normal viable fetus presenting with severe pre-eclampsia: a case report. ( 29779493 )
2018
38
Severe tricuspid regurgitation and seizure on postpartum day 10: case report of late postpartum eclampsia. ( 29451101 )
2018
39
LncRNA PRNCR1 promoted the progression of eclampsia by regulating the MAPK signal pathway. ( 29949134 )
2018
40
Pre-eclampsia affects procalcitonin production in placental tissue. ( 29427369 )
2018
41
Pre-Eclampsia: A Twilight Zone Between Health and Cardiovascular Disease? ( 29957220 )
2018
42
Twin gestation in a Swyer syndrome patient with superimposed pre-eclampsia. ( 29421927 )
2018
43
Changes in the Expression of AQP4 and AQP9 in the Hippocampus Following Eclampsia-Like Seizure. ( 29351212 )
2018
44
Acute Cardiac Effects of SevereA Pre-Eclampsia. ( 29957219 )
2018
45
Lipid profile, plasma apolipoproteins, and pre-eclampsia risk in the GenPE case-control study. ( 29914672 )
2018
46
Effect of iron supplementation during early pregnancy on the development of gestational hypertension and pre-eclampsia. ( 29951711 )
2018
47
Severe pre-eclampsia among pregnant women with sickle cell disease and HIV. ( 29523281 )
2018
48
Transient diabetes insipidus in a post-partum woman with pre-eclampsia associated with residual placental vasopressinase activity. ( 29850023 )
2018
49
Aspirin non-responsiveness in pregnant women at high-risk of pre-eclampsia. ( 29304392 )
2018
50
Management of pregnancies after combined screening for pre-eclampsia at 19-24a88weeks' gestation. ( 29943498 )
2018

Variations for Eclampsia

Expression for Eclampsia

Search GEO for disease gene expression data for Eclampsia.

Pathways for Eclampsia

Pathways related to Eclampsia according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
10.16 FLT1 PGF
2 9.8 EPHX1 F2

GO Terms for Eclampsia

Cellular components related to Eclampsia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.7 ALB CORIN EDN1 F2 FLT1 HLA-G
2 extracellular space GO:0005615 9.36 ALB EDN1 ENG F2 FLT1 INHBB

Biological processes related to Eclampsia according to GeneCards Suite gene sharing:

(show all 13)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 9.88 EDN1 F2 FLT1 PGF STOX1
2 response to drug GO:0042493 9.83 EDN1 ENG MTHFR PGF
3 regulation of signaling receptor activity GO:0010469 9.72 EDN1 F2 INHBB OXT PGF
4 negative regulation of blood coagulation GO:0030195 9.51 EDN1 THBD
5 positive regulation of renal sodium excretion GO:0035815 9.49 EDN1 OXT
6 regulation of blood coagulation GO:0030193 9.46 F2 SERPINC1
7 negative regulation of fibrinolysis GO:0051918 9.43 F2 THBD
8 response to transforming growth factor beta GO:0071559 9.4 EDN1 ENG
9 negative regulation of platelet activation GO:0010544 9.37 F2 THBD
10 hemostasis GO:0007599 9.33 F2 SERPINC1 THBD
11 positive regulation of prostaglandin secretion GO:0032308 9.26 EDN1 OXT
12 sprouting angiogenesis GO:0002040 9.13 ENG FLT1 PGF
13 female pregnancy GO:0007565 9.02 CORIN OXT PGF TAC3 THBD

Molecular functions related to Eclampsia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 8.8 EDN1 INHBB OXT

Sources for Eclampsia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....