MCID: ECL001
MIFTS: 59

Eclampsia

Categories: Blood diseases, Cardiovascular diseases, Nephrological diseases, Rare diseases, Reproductive diseases, Respiratory diseases

Aliases & Classifications for Eclampsia

Summaries for Eclampsia

Disease Ontology : 12 A pre-eclampsia characterized by the presence of seizures.

MalaCards based summary : Eclampsia, also known as eclampsia in puerperium, is related to severe pre-eclampsia and hellp syndrome, and has symptoms including seizures An important gene associated with Eclampsia is STOX1 (Storkhead Box 1), and among its related pathways/superpathways are Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) and Warfarin Pathway, Pharmacodynamics. The drugs Methyldopa and Calcium Carbonate have been mentioned in the context of this disorder. Affiliated tissues include placenta, endothelial and testes, and related phenotypes are cardiovascular system and homeostasis/metabolism

Wikipedia : 77 Eclampsia is the onset of seizures (convulsions) in a woman with pre-eclampsia. Pre-eclampsia is a... more...

Related Diseases for Eclampsia

Diseases in the Eclampsia family:

Pre-Eclampsia Severe Pre-Eclampsia

Diseases related to Eclampsia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 296)
# Related Disease Score Top Affiliating Genes
1 severe pre-eclampsia 33.6 ALB HLA-G PGF SERPINC1
2 hellp syndrome 30.7 EDN1 ENG F2 FLT1 MTHFR PGF
3 placental insufficiency 30.5 F2 FLT1 PGF
4 pre-eclampsia 30.2 C19orf33 CORIN EDN1 ENG EPHX1 F2
5 microvascular complications of diabetes 5 29.8 ALB FLT1 PGF
6 retinal vein occlusion 29.6 F2 MTHFR SERPINC1
7 antiphospholipid syndrome 29.6 F2 MTHFR SERPINC1 THBD
8 disseminated intravascular coagulation 29.5 F2 SERPINC1 THBD
9 thrombophilia 29.5 F2 MTHFR SERPINC1 THBD
10 purpura 29.4 F2 SERPINC1 THBD
11 hepatorenal syndrome 29.3 ALB EDN1 F2
12 antithrombin iii deficiency 29.3 F2 MTHFR SERPINC1
13 central retinal vein occlusion 29.3 F2 MTHFR SERPINC1
14 portal vein thrombosis 29.3 F2 MTHFR SERPINC1
15 thrombosis 29.2 F2 MTHFR SERPINC1 THBD
16 budd-chiari syndrome 29.2 F2 MTHFR SERPINC1
17 placental abruption 29.2 ENG F2 FLT1 MTHFR PGF SERPINC1
18 homocysteinemia 29.0 ALB F2 MTHFR SERPINC1
19 pulmonary embolism 29.0 ALB F2 MTHFR SERPINC1
20 hepatic infarction 28.8 F2 MTHFR OXT SERPINC1
21 heart disease 28.8 ALB EDN1 F2 MTHFR SERPINC1
22 stroke, ischemic 28.7 F2 MTHFR SERPINC1 THBD
23 placenta disease 28.7 MTHFR OXT PAPPA PGF SERPINC1
24 arteries, anomalies of 28.7 ALB EDN1 FLT1 PGF SERPINC1
25 vascular disease 28.2 ALB EDN1 ENG F2 MTHFR SERPINC1
26 myocardial infarction 27.7 ALB EDN1 F2 MTHFR PAPPA PGF
27 preeclampsia/eclampsia 5 12.6
28 preeclampsia/eclampsia 4 12.5
29 mild pre-eclampsia 12.5
30 preeclampsia/eclampsia 1 12.1
31 preeclampsia/eclampsia 2 12.1
32 preeclampsia/eclampsia 3 12.1
33 gestational diabetes 11.4
34 chorea gravidarum 11.1
35 encephalopathy 10.5
36 glomeruloid hemangioma 10.4 ENG FLT1
37 twin-to-twin transfusion syndrome 10.4 ENG FLT1 PGF
38 hydatidiform mole, recurrent, 1 10.3
39 gestational trophoblastic neoplasm 10.3
40 hypoxia 10.3
41 diabetes mellitus 10.3
42 cortical blindness 10.3
43 mesenteric vascular occlusion 10.2 F2 MTHFR
44 antipyrine metabolism 10.2 ALB F2
45 non-a-e hepatitis 10.2 ALB F2
46 sudden sensorineural hearing loss 10.2 F2 MTHFR
47 epstein-barr virus hepatitis 10.2 ALB F2
48 retinal detachment 10.2
49 abdominal tuberculosis 10.2 ALB F2
50 ischemic neuropathy 10.2 F2 MTHFR

Graphical network of the top 20 diseases related to Eclampsia:



Diseases related to Eclampsia

Symptoms & Phenotypes for Eclampsia

UMLS symptoms related to Eclampsia:


seizures

MGI Mouse Phenotypes related to Eclampsia:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.11 CORIN EDN1 ENG F2 FLT1 NOSTRIN
2 homeostasis/metabolism MP:0005376 10.06 ALB CORIN EDN1 ENG EPHX1 F2
3 growth/size/body region MP:0005378 10.03 CORIN EDN1 ENG F2 FLT1 INHBB
4 digestive/alimentary MP:0005381 9.92 ALB EDN1 ENG F2 INHBB OXT
5 integument MP:0010771 9.56 CORIN ENG F2 INHBB MTHFR OXT
6 normal MP:0002873 9.23 ALB EDN1 ENG F2 FLT1 PAPPA

Drugs & Therapeutics for Eclampsia

Drugs for Eclampsia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 407)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Methyldopa Approved Phase 4,Phase 2,Phase 1,Not Applicable 555-30-6 38853
2
Calcium Carbonate Approved, Investigational Phase 4,Not Applicable 471-34-1
3
Remifentanil Approved Phase 4,Phase 2 132875-61-7 60815
4
Metformin Approved Phase 4,Phase 3,Phase 2,Not Applicable 657-24-9 14219 4091
5
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 50-78-2 2244
6
Dalteparin Approved Phase 4,Phase 2,Phase 3,Early Phase 1,Not Applicable 9005-49-6
7
Enoxaparin Approved Phase 4,Phase 3,Not Applicable 9005-49-6 772
8
leucovorin Approved Phase 4,Phase 3,Phase 2,Not Applicable 58-05-9 6006 143
9
Heparin Approved, Investigational Phase 4,Phase 2,Phase 3,Early Phase 1,Not Applicable 9005-49-6 772 46507594
10
Phenylephrine Approved Phase 4,Not Applicable 59-42-7 6041
11
Ephedrine Approved Phase 4,Phase 3,Not Applicable 299-42-3 9294
12
Pseudoephedrine Approved Phase 4,Phase 3,Not Applicable 90-82-4 7028
13
Oxymetazoline Approved, Investigational Phase 4,Not Applicable 1491-59-4 4636
14
Oxytocin Approved, Vet_approved Phase 4,Phase 3,Not Applicable,Early Phase 1 50-56-6 439302 53477758
15
Rocuronium Approved Phase 4 119302-91-9, 143558-00-3 441290
16
Magnesium Sulfate Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 7487-88-9 24083
17
Acetaminophen Approved Phase 4,Phase 2,Phase 3 103-90-2 1983
18
Ibuprofen Approved Phase 4,Phase 2,Phase 3 15687-27-1 3672
19
Furosemide Approved, Vet_approved Phase 4 54-31-9 3440
20
Levobupivacaine Approved, Investigational Phase 4 27262-47-1 92253
21
Clonidine Approved Phase 4,Phase 1,Phase 2 4205-90-7 2803
22
Captopril Approved Phase 4 62571-86-2 44093
23
Nifedipine Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1 21829-25-4 4485
24
Labetalol Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 36894-69-6 3869
25
Insulin Aspart Approved Phase 4,Phase 3 116094-23-6 16132418
26
Insulin Lispro Approved Phase 4 133107-64-9
27
Zinc Approved, Investigational Phase 4,Phase 3,Not Applicable 7440-66-6 32051
28
Azithromycin Approved Phase 4,Phase 3 83905-01-5 55185 447043
29
Ketorolac Approved Phase 4 66635-83-4, 74103-06-3 3826
30
tannic acid Approved Phase 4,Phase 3,Not Applicable 1401-55-4
31
Benzocaine Approved, Investigational Phase 4,Phase 3,Not Applicable 94-09-7, 1994-09-7 2337
32
Desogestrel Approved Phase 4 54024-22-5 40973
33
Etonogestrel Approved, Investigational Phase 4 54048-10-1 40976 6917715
34
Calcium Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 7440-70-2 271
35
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 59-30-3 6037
36
Vitamin D Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 1406-16-2
37
Ergocalciferol Approved, Nutraceutical Phase 4,Phase 1,Phase 2,Not Applicable 50-14-6 5280793
38
Vitamin D3 Approved, Nutraceutical Phase 4,Phase 1,Phase 2,Not Applicable 67-97-0 5280795 6221
39
Serine Approved, Nutraceutical Phase 4,Phase 3,Early Phase 1 56-45-1 5951
40 Antihypertensive Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
41 Adrenergic alpha-Agonists Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
42 Adrenergic Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
43 Sympatholytics Phase 4,Phase 2,Phase 1,Early Phase 1,Not Applicable
44 Adrenergic alpha-2 Receptor Agonists Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
45 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
46 Adrenergic Agonists Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
47 Autonomic Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
48 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
49 Bone Density Conservation Agents Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
50 Hormones Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1

Interventional clinical trials:

(show top 50) (show all 583)
# Name Status NCT ID Phase Drugs
1 Anti-Hypertensive Treatment In Stable Pregnant Women With Severe Pre-Eclampsia (Metildopape) Unknown status NCT01361425 Phase 4 methildopa;placebo
2 Cardiovascular and Autonomic Reactivity in Women With a History of Pre-eclampsia Unknown status NCT00117546 Phase 4 alpha methyldopa
3 Low Dose Calcium to Prevent Preeclampsia Unknown status NCT02338687 Phase 4
4 Remifentanil for General Anesthesia in Preeclamptics Unknown status NCT00567957 Phase 4 Remifentanil;Saline
5 Metformin and Gestational Diabetes in High-risk Patients: a RCTs Unknown status NCT00883259 Phase 4 Metformin
6 Prevention of Pre-eclampsia and SGA by Low-Dose Aspirin in Nulliparous Women With Abnormal First-trimester Uterine Artery Dopplers Completed NCT01729468 Phase 4 Aspirin;Placebo
7 Trial of Early Screening Test for Pre-eclampsia and Growth Restriction Completed NCT03674606 Phase 4 Low dose aspirin
8 Effects of Magnesium Sulphate on Sugammadex Reversal of Rocuronium Induced Blockade in Gynaecology Patients Completed NCT01972659 Phase 4 placebo;Magnesium Sulphate;sugammadex
9 The Effect of Ibuprofen on Post-partum Blood Pressure in Women With Hypertensive Disorders of Pregnancy Completed NCT02891174 Phase 4 Ibuprofen;Acetaminophen
10 Diuretics for Postpartum High Blood Pressure in Preeclampsia Completed NCT02163655 Phase 4 FUROSEMIDE;Placebo
11 Treatment Approaches to Preeclampsia Completed NCT01030627 Phase 4
12 Effectiveness Study of Short Course of Magnesium Sulfate for Severe Preeclamsia Completed NCT01408979 Phase 4 Magnesium sulfate 12 hours;Magnesium sulfate 24 hours
13 Comparison of Doses of Acetylsalicylic Acid in Women With Previous History of Preeclampsia Completed NCT01352234 Phase 4 Acetylsalicylic Acid 160 mg;Acetylsalicylic Acid 80 mg
14 Low Molecular Weight Heparin in Recurrent Miscarriage With Negative Antiphospholipid Antibodies Completed NCT01608347 Phase 4 LMWH+Folic acid;Folic Acid
15 Adding MgSO4 to Epidural Levobupivacaine in CS for Patients With Preeclampsia Completed NCT02699827 Phase 4 Levobupivacaine hydrochloride;Magnesium sulphate;Saline 0.9%
16 A Trial Comparing Treatment With the Springfusor Infusion Pump to the IV Magnesium Sulfate Regimen Completed NCT02091401 Phase 4 Magnesium Sulfate
17 Clonidine Versus Captopril for Treatment of Postpartum Very High Blood Pressure Completed NCT01761916 Phase 4 CLONIDINE;CAPTOPRIL
18 Oral Antihypertensive Regimens for Management of Hypertension in Pregnancy Completed NCT01912677 Phase 4 Nifedipine;Labetalol;Methyldopa
19 Metformin Versus Insulin in Gestational Diabetes Completed NCT01240785 Phase 4 metformin;insulin
20 Efficacy of Corifollitropin Alfa Versus Follitropin Beta in Aged IVF (In-vitro Fertilization) Patients Completed NCT02466204 Phase 4 corifollitropin alfa;Follitropin Beta
21 Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' Boostrix™ Vaccine in Pregnant Women Completed NCT02377349 Phase 4 Saline placebo
22 Phenylephrine Versus Ephedrine in Pre-eclampsia Recruiting NCT02025426 Phase 4 Phenylephrine;Ephedrine
23 Efficacy and Safety of 1 g Vs 2 g Per Hour Intravenous Maintenance Dose of MgSO4 in Women With Severe Pre-eclampsia Recruiting NCT03164304 Phase 4 Magnesium Sulfate
24 Impact of Antichlamydial Treatment on the Rate of Preeclampsia Recruiting NCT03233880 Phase 4 Azithromycin 1gm
25 Early Vascular Adjustments During Hypertensive Pregnancy Recruiting NCT02531490 Phase 4 Labetalol;Nifedipine;Methyldopa
26 Oral Nifedipine Versus Labetalol in Treatment of Postpartum Hypertension Recruiting NCT03449277 Phase 4 Oral Tablet
27 A Randomized Control Trial of Vitamin D Prophylaxis in the Prevention of Hypertensive Disorders of Pregnancy Recruiting NCT02920593 Phase 4 Vitamin D3
28 Acute Labetalol Use in Preeclampsia Recruiting NCT03872336 Phase 4 Experimental labetalol dose
29 The Effect of Two Aspirin Dosing Strategies for Obese Women at High Risk for Preeclampsia Recruiting NCT03735433 Phase 4 162mg aspirin dose
30 Acute Control of Chronic Hypertension Recruiting NCT03877692 Phase 4 Experimental dosing of labetalol
31 Postpartum NSAIDS and Maternal Hypertension Recruiting NCT03824119 Phase 4 Ibuprofen 600 mg
32 Response to Anti-hypertensives in Pregnant and Postpartum Patients Recruiting NCT03506724 Phase 4 Nifedipine;Labetalol
33 Continued Versus Discontinued Oxytocin Stimulation of Labour Recruiting NCT02553226 Phase 4 Oxytocin;Placebo
34 Chronic Hypertension and Pregnancy (CHAP) Project Recruiting NCT02299414 Phase 4 Anti-hypertensive therapy
35 Effect of Acetaminophen on Postpartum Blood Pressure Control in Preeclampsia With Severe Features Active, not recruiting NCT02911701 Phase 4 Acetaminophen;Ibuprofen
36 Contraception in Women With Sickle Cell Disease Active, not recruiting NCT02594462 Phase 4 etonogestrel-releasing implant contraceptive
37 Discontinuation of Magnesium Sulfate After Delivery in Women With Severe Preeclampsia. A Randomized Controlled Trial Not yet recruiting NCT03318211 Phase 4 Magnesium Sulfate
38 Effect of Administering Intravenous Magnesium Sulfate on Fetal Cardiotocography and Neonatal Outcome in Preeclamptic Patients Not yet recruiting NCT03237000 Phase 4 MgSO4
39 Metformin Use to Improve Pregnancy Outcome in Women With Type 1 Diabetes. Not yet recruiting NCT03765359 Phase 4 metforminhydrochloride;Placebo Oral Tablet
40 Metformin for Preeclampsia Prevention in Pregnant Women With Type 1 Diabetes Mellitus Not yet recruiting NCT03570632 Phase 4 Metformin
41 Different Schemes of Magnesium Sulfate for Preeclampsia Terminated NCT02396030 Phase 4 Magnesium sulfate 50% - 1g/h;Magnesium sulfate 50% - 2g/h
42 Atenativ Effect on Uterine Blood Flow and Preeclampsia Withdrawn NCT02278575 Phase 4 Atenativ
43 Investigating the Novel Observation of Right-Left Difference in Uterine Artery Vascular Resistance in Pre-Eclampsia Unknown status NCT00848679 Phase 3 Epidural lidocaine;Epidural lidocaine 2%
44 Treatment of Severe Hypertension During Pre-Eclampsia: A Preliminary Equivalence Study Between Urapidil and Nicardipine Unknown status NCT00409253 Phase 3 URAPIDIL (EUPRESSYL*);NICARDIPINE
45 Prospects for the Prevention of Pregnancy-induced Hypertension and Preeclampsia Trial Unknown status NCT02007837 Phase 3 Combined aspirin and multinutrient supplement
46 A Randomized Trial of Docosahexaenoic Acid Supplementation During Pregnancy to Prevent Deep Placentation Disorders Unknown status NCT02336243 Phase 3
47 Carbetocin vs. Oxytocin for Prevention of Postpartum Bleeding in Patients With Severe Preeclampsia Unknown status NCT01382732 Phase 3 Carbetocin;Oxytocin
48 A Randomized Clinical Trial of Oral Magnesium Supplementation in Pregnancy Unknown status NCT02032186 Phase 3 Magnesium citrate
49 Low Dose Aspirin for the Prevention of Preeclampsia Unknown status NCT01890005 Phase 3 Aspirin;Placebo
50 PP13 and Doppler Study to Predict Preeclampsia Unknown status NCT00928213 Phase 2, Phase 3 Progesterone;Low molecular weight Heparin;No Drug

Search NIH Clinical Center for Eclampsia

Inferred drug relations via UMLS 74 / NDF-RT 52 :


Cochrane evidence based reviews: eclampsia

Genetic Tests for Eclampsia

Genetic tests related to Eclampsia:

# Genetic test Affiliating Genes
1 Eclampsia 30

Anatomical Context for Eclampsia

MalaCards organs/tissues related to Eclampsia:

42
Placenta, Endothelial, Testes, Kidney, Heart, Thyroid, Brain

Publications for Eclampsia

Articles related to Eclampsia:

(show top 50) (show all 4040)
# Title Authors Year
1
Resveratrol promotes trophoblast invasion in pre-eclampsia by inducing epithelial-mesenchymal transition. ( 30710417 )
2019
2
Relationship between antithrombin activity and interval from diagnosis to delivery among pregnant women with early-onset pre-eclampsia. ( 30714139 )
2019
3
Correction: High-Resolution Genetic and Phenotypic Analysis of KIR2DL1 Alleles and Their Association with Pre-Eclampsia. ( 30728211 )
2019
4
The clinical enigma of the "Flea catcher" by Georges de La Tour: a pregnant sinner with pre-eclampsia or a hypothyroid girl? ( 30730039 )
2019
5
Successful rescue of antepartum eclampsia in a Chinese patient: Case report. ( 30732147 )
2019
6
Increased biosynthesis and accumulation of cholesterol in maternal plasma, but not amniotic fluid in pre-eclampsia. ( 30733456 )
2019
7
Adverse Maternal and Fetal Outcome in Patients with Eclampsia. ( 30739934 )
2019
8
Fetomaternal Outcome in Eclampsia in Relationship with Gravidity. ( 30755549 )
2019
9
Decreased Filamin b expression regulates trophoblastic cells invasion through ERK/MMP-9 pathway in pre-eclampsia. ( 30756369 )
2019
10
The ability of thromboelastography parameters to predict severe pre-eclampsia when measured during early pregnancy. ( 30763470 )
2019
11
Influence of NKG2C gene deletion and CCR5Δ32 in Pre-eclampsia-Approaching the effect of innate immune gene variants in pregnancy. ( 30786156 )
2019
12
Pre-eclampsia: pathogenesis, novel diagnostics and therapies. ( 30792480 )
2019
13
Relationships of serum placental growth factor and soluble fms-like tyrosine kinase-1 with fetal and uterine artery Doppler indices in pre-eclampsia. ( 30801711 )
2019
14
Evaluation of a simple risk score to predict preterm preeclampsia using maternal characteristics: a prospective cohort study. ( 30801934 )
2019
15
Aspirin and heparin for the prevention of pre-eclampsia: protocol for a systematic review and network meta-analysis. ( 30804037 )
2019
16
Increased expression and phosphorylation of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase isoforms in urinary exosomes in pre-eclampsia. ( 30819197 )
2019
17
Policy review on the management of pre-eclampsia and eclampsia by community health workers in Mozambique. ( 30819211 )
2019
18
Signalling of ERK1/2, P38MAPK and P90RSK in HIV-associated pre-eclampsia. ( 30821550 )
2019
19
Maternal serum lipid levels, oxidative stress and antioxidant activity in pre-eclampsia patients from Southwest India. ( 30825910 )
2019
20
Temporal and external validation of the fullPIERS model for the prediction of adverse maternal outcomes in women with pre-eclampsia. ( 30825926 )
2019
21
PARROT Ireland: Placental growth factor in Assessment of women with suspected pre-eclampsia to reduce maternal morbidity: a Stepped Wedge Cluster Randomised Control Trial Research Study Protocol. ( 30826791 )
2019
22
Human chorionic gonadotropin and the risk of pre-eclampsia: a prospective population-based cohort study. ( 30834627 )
2019
23
An integrated model of materno-foetal cardiac dysfunction in severe pre-eclampsia. ( 30839049 )
2019
24
Reactive Species Interactome Alterations in Oocyte Donation Pregnancies in the Absence and Presence of Pre-Eclampsia. ( 30845762 )
2019
25
Liver rupture in a 28-year-old primigravida with superimposed pre-eclampsia and hemolysis, elevated liver enzyme levels, and low platelet count syndrome. ( 30854740 )
2019
26
ELABELA, as a potential diagnostic biomarker of pre-eclampsia, regulates abnormally shallow placentation via APJ. ( 30860880 )
2019
27
lncRNA GHET1 has effects in development of pre-eclampsia. ( 30861585 )
2019
28
Ready for prime time - prediction of preterm pre-eclampsia. ( 30864241 )
2019
29
Association of Foxp3 and TGF-β1 Polymorphisms with Pre-Eclampsia Risk in Chinese Women. ( 30875252 )
2019
30
Perinatal outcomes of severe preeclampsia/eclampsia and associated factors among mothers admitted in Amhara Region referral hospitals, North West Ethiopia, 2018. ( 30876447 )
2019
31
Incidence and outcomes of eclampsia: a single-center 30-year study. ( 30880504 )
2019
32
Pre-eclampsia causing severe maternal morbidity - A national retrospective review of preventability and opportunities for improved care. ( 30883684 )
2019
33
Validation of competing risks model in screening for pre-eclampsia in twin pregnancy by maternal factors. ( 30887621 )
2019
34
Upregulated long noncoding RNA Linc00261 in pre-eclampsia and its effect on trophoblast invasion and migration via regulating miR-558/TIMP4 signaling pathway. ( 30891826 )
2019
35
Placental growth factor in pre-eclampsia: friend or foe? ( 30904058 )
2019
36
Posterior reversible encephalopathy syndrome associated with reversible cerebral vasoconstriction syndrome in a patient presenting with postpartum eclampsia: a case report. ( 30905853 )
2019
37
Improving the knowledge of pregnant women using a pre-eclampsia app: A controlled before and after study. ( 30914185 )
2019
38
SEMA3B but Not CUL1 as Marker for Pre-Eclampsia Progression. ( 30914894 )
2019
39
Toll-like receptors signaling network in pre-eclampsia: An updated review. ( 30221394 )
2019
40
Pre-eclampsia/Eclampsia as a Risk Factor of Noninfectious Uveitis Among Postdelivery Women. ( 30316670 )
2019
41
ISUOG Practice Guidelines: role of ultrasound in screening for and follow-up of pre-eclampsia. ( 30320479 )
2019
42
Placental Elasticity as a New Non-invasive Predictive Marker of Pre-eclampsia. ( 30342781 )
2019
43
Maternal serum uric acid concentration and pregnancy outcomes in women with pre-eclampsia/eclampsia. ( 30353543 )
2019
44
Neutrophil-to-lymphocyte ratio and platelet indices in pre-eclampsia. ( 30362112 )
2019
45
Changes in calcium channel proteins according to magnesium sulfate administration in placentas from pregnancies with pre-eclampsia or fetal growth restriction. ( 30415221 )
2019
46
Pre-eclampsia onset and SPARC: A possible involvement in placenta development. ( 30426491 )
2019
47
Influential factors and clinical significance of an atypical presentation of posterior reversible encephalopathy syndrome in patients with eclampsia. ( 30478719 )
2019
48
A novel RNA interference approach to targeting sFLT1 in pre-eclampsia. ( 30514974 )
2019
49
Profound bilateral post-partum retinal circulation ischemia in two diabetic mothers with pre-eclampsia. ( 30519670 )
2019
50
Assessing the effect of dexmedetomidine in patients with pre-eclampsia. ( 30520788 )
2019

Variations for Eclampsia

Expression for Eclampsia

Search GEO for disease gene expression data for Eclampsia.

Pathways for Eclampsia

Pathways related to Eclampsia according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.28 F2 PAPPA
2 9.8 EPHX1 F2

GO Terms for Eclampsia

Cellular components related to Eclampsia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.73 ALB CORIN EDN1 F2 FLT1 HLA-G
2 extracellular space GO:0005615 9.4 ALB EDN1 ENG F2 FLT1 INHBB

Biological processes related to Eclampsia according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 9.89 EDN1 F2 FLT1 PGF STOX1
2 response to drug GO:0042493 9.84 EDN1 ENG MTHFR PGF
3 regulation of signaling receptor activity GO:0010469 9.65 EDN1 F2 INHBB OXT PGF
4 cellular protein metabolic process GO:0044267 9.62 ALB F2 PAPPA SERPINC1
5 vascular endothelial growth factor signaling pathway GO:0038084 9.52 FLT1 PGF
6 negative regulation of blood coagulation GO:0030195 9.51 EDN1 THBD
7 positive regulation of renal sodium excretion GO:0035815 9.48 EDN1 OXT
8 regulation of blood coagulation GO:0030193 9.46 F2 SERPINC1
9 response to transforming growth factor beta GO:0071559 9.43 EDN1 ENG
10 negative regulation of fibrinolysis GO:0051918 9.4 F2 THBD
11 negative regulation of platelet activation GO:0010544 9.37 F2 THBD
12 positive regulation of prostaglandin secretion GO:0032308 9.16 EDN1 OXT
13 hemostasis GO:0007599 9.13 F2 SERPINC1 THBD
14 female pregnancy GO:0007565 9.1 CORIN OXT PAPPA PGF TAC3 THBD

Molecular functions related to Eclampsia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 8.8 EDN1 INHBB OXT

Sources for Eclampsia

3 CDC
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10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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