MCID: ECL001
MIFTS: 57

Eclampsia

Categories: Blood diseases, Cardiovascular diseases, Nephrological diseases, Rare diseases, Reproductive diseases, Respiratory diseases

Aliases & Classifications for Eclampsia

Summaries for Eclampsia

Disease Ontology : 12 A pre-eclampsia characterized by the presence of seizures.

MalaCards based summary : Eclampsia, also known as eclampsia in puerperium, is related to severe pre-eclampsia and pre-eclampsia, and has symptoms including seizures An important gene associated with Eclampsia is STOX1 (Storkhead Box 1), and among its related pathways/superpathways are VEGF binds to VEGFR leading to receptor dimerization and Warfarin Pathway, Pharmacodynamics. The drugs Methyldopa and Calcium Carbonate have been mentioned in the context of this disorder. Affiliated tissues include endothelial, placenta and testes, and related phenotypes are cardiovascular system and growth/size/body region

Wikipedia : 76 Eclampsia is the onset of seizures (convulsions) in a woman with pre-eclampsia. Pre-eclampsia is a... more...

Related Diseases for Eclampsia

Diseases in the Eclampsia family:

Pre-Eclampsia Severe Pre-Eclampsia

Diseases related to Eclampsia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 261)
# Related Disease Score Top Affiliating Genes
1 severe pre-eclampsia 33.7 ALB HLA-G LGALS13 PGF SERPINC1
2 pre-eclampsia 31.8 C19orf33 CORIN EDN1 ENG EPHX1 F2
3 hellp syndrome 31.4 EDN1 ENG F2 FLT1 LGALS13 MTHFR
4 placental insufficiency 30.4 F2 FLT1 PGF
5 antiphospholipid syndrome 29.9 F2 MTHFR SERPINC1 THBD
6 retinal vein occlusion 29.9 F2 MTHFR SERPINC1
7 placental abruption 29.9 ENG F2 FLT1 MTHFR PGF SERPINC1
8 thrombophilia 29.8 F2 MTHFR SERPINC1 THBD
9 placenta disease 29.8 MTHFR OXT PGF SERPINC1
10 microvascular complications of diabetes 5 29.7 ALB FLT1 PGF
11 hepatorenal syndrome 29.6 ALB EDN1 F2
12 antithrombin iii deficiency 29.5 F2 MTHFR SERPINC1
13 central retinal vein occlusion 29.5 F2 MTHFR SERPINC1
14 portal vein thrombosis 29.5 F2 MTHFR SERPINC1
15 heart disease 29.5 ALB EDN1 F2 MTHFR SERPINC1
16 purpura 29.4 F2 SERPINC1 THBD
17 homocysteinemia 29.3 ALB F2 MTHFR SERPINC1
18 pulmonary embolism 29.3 ALB F2 MTHFR SERPINC1
19 thrombosis 29.3 F2 MTHFR SERPINC1 THBD
20 hepatic infarction 29.2 F2 MTHFR OXT SERPINC1
21 vascular disease 29.1 ALB EDN1 ENG F2 MTHFR SERPINC1
22 myocardial infarction 28.6 ALB EDN1 ENG F2 MTHFR PGF
23 preeclampsia/eclampsia 5 12.5
24 preeclampsia/eclampsia 4 12.5
25 mild pre-eclampsia 12.4
26 preeclampsia/eclampsia 1 12.1
27 preeclampsia/eclampsia 2 12.1
28 preeclampsia/eclampsia 3 12.1
29 gestational diabetes 11.4
30 chorea gravidarum 11.0
31 encephalopathy 10.4
32 hypoxia 10.3
33 cortical blindness 10.3
34 glomeruloid hemangioma 10.3 ENG FLT1
35 twin-to-twin transfusion syndrome 10.2 ENG FLT1 PGF
36 diabetes mellitus 10.2
37 hydatidiform mole, recurrent, 1 10.2
38 gestational trophoblastic neoplasm 10.2
39 antipyrine metabolism 10.2 ALB F2
40 non-a-e hepatitis 10.2 ALB F2
41 mesenteric vascular occlusion 10.2 F2 MTHFR
42 epstein-barr virus hepatitis 10.2 ALB F2
43 sudden sensorineural hearing loss 10.2 F2 MTHFR
44 abdominal tuberculosis 10.1 ALB F2
45 ischemic neuropathy 10.1 F2 MTHFR
46 retinal vascular disease 10.1 ALB FLT1 MTHFR PGF
47 chronic thromboembolic pulmonary hypertension 10.1 EDN1 F2
48 polymorphic reticulosis 10.1
49 parametritis 10.1 F2 OXT
50 cryptogenic cirrhosis 10.1 F2 MTHFR

Graphical network of the top 20 diseases related to Eclampsia:



Diseases related to Eclampsia

Symptoms & Phenotypes for Eclampsia

UMLS symptoms related to Eclampsia:


seizures

MGI Mouse Phenotypes related to Eclampsia:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.02 CORIN EDN1 ENG F2 FLT1 NOSTRIN
2 growth/size/body region MP:0005378 9.9 CORIN EDN1 ENG F2 FLT1 INHBB
3 digestive/alimentary MP:0005381 9.86 ALB EDN1 ENG F2 INHBB OXT
4 homeostasis/metabolism MP:0005376 9.83 ALB CORIN EDN1 ENG EPHX1 F2
5 integument MP:0010771 9.23 CORIN ENG F2 INHBB MTHFR OXT

Drugs & Therapeutics for Eclampsia

Drugs for Eclampsia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 393)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Methyldopa Approved Phase 4,Phase 2,Phase 1,Not Applicable 555-30-6 38853
2
Calcium Carbonate Approved, Investigational Phase 4,Not Applicable 471-34-1
3
Remifentanil Approved Phase 4,Phase 2 132875-61-7 60815
4
Amlodipine Approved Phase 4 88150-42-9 2162
5
Metformin Approved Phase 4,Phase 3,Phase 2,Not Applicable 657-24-9 14219 4091
6
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 50-78-2 2244
7
Heparin Approved, Investigational Phase 4,Phase 2,Phase 3,Early Phase 1,Not Applicable 9005-49-6 772 46507594
8
Enoxaparin Approved Phase 4,Phase 3,Not Applicable 9005-49-6 772
9
Dalteparin Approved Phase 4,Phase 2,Phase 3,Early Phase 1,Not Applicable 9005-49-6
10
leucovorin Approved Phase 4,Phase 3,Phase 2,Not Applicable 58-05-9 6006 143
11
Bupivacaine Approved, Investigational Phase 4,Phase 3,Not Applicable 2180-92-9, 38396-39-3 2474
12
Pseudoephedrine Approved Phase 4,Phase 3,Not Applicable 90-82-4 7028
13
Phenylephrine Approved Phase 4,Not Applicable 59-42-7 6041
14
Oxymetazoline Approved, Investigational Phase 4,Not Applicable 1491-59-4 4636
15
Ephedrine Approved Phase 4,Phase 3,Not Applicable 299-42-3 9294
16
Oxytocin Approved, Vet_approved Phase 4,Phase 3,Not Applicable,Early Phase 1 50-56-6 439302 53477758
17
Rocuronium Approved Phase 4 119302-91-9, 143558-00-3 441290
18
Magnesium Sulfate Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 7487-88-9 24083
19
Ibuprofen Approved Phase 4,Phase 2,Phase 3 15687-27-1 3672
20
Acetaminophen Approved Phase 4,Phase 2,Phase 3 103-90-2 1983
21
Furosemide Approved, Vet_approved Phase 4 54-31-9 3440
22
Levobupivacaine Approved, Investigational Phase 4 27262-47-1 92253
23
Clonidine Approved Phase 4,Phase 1,Phase 2,Not Applicable 4205-90-7 2803
24
Captopril Approved Phase 4 62571-86-2 44093
25
Nifedipine Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1 21829-25-4 4485
26
Labetalol Approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 36894-69-6 3869
27
Insulin Aspart Approved Phase 4,Phase 3 116094-23-6 16132418
28
Zinc Approved, Investigational Phase 4,Phase 3,Not Applicable 7440-66-6
29
Insulin Lispro Approved Phase 4 133107-64-9
30
Azithromycin Approved Phase 4,Phase 3 83905-01-5 55185 447043
31
Benzocaine Approved, Investigational Phase 4,Phase 3,Not Applicable 94-09-7, 1994-09-7 2337
32 tannic acid Approved Phase 4,Phase 3,Not Applicable
33
Desogestrel Approved Phase 4 54024-22-5 40973
34
Etonogestrel Approved, Investigational Phase 4 54048-10-1 6917715 40976
35
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 59-30-3 6037
36
Ergocalciferol Approved, Nutraceutical Phase 4,Phase 1,Phase 2,Not Applicable 50-14-6 5280793
37
Vitamin D Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 1406-16-2
38
Vitamin D3 Approved, Nutraceutical Phase 4,Phase 1,Phase 2,Not Applicable 67-97-0 5280795 6221
39
Serine Approved, Nutraceutical Phase 4,Phase 3,Early Phase 1 56-45-1 5951
40 Antihypertensive Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
41 Adrenergic Agonists Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
42 Adrenergic alpha-Agonists Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
43 Autonomic Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1
44 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
45 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
46 Adrenergic Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
47 Adrenergic alpha-2 Receptor Agonists Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
48 Sympatholytics Phase 4,Phase 2,Phase 1,Early Phase 1,Not Applicable
49 Bone Density Conservation Agents Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
50 Calcium, Dietary Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1

Interventional clinical trials:

(show top 50) (show all 569)
# Name Status NCT ID Phase Drugs
1 Anti-Hypertensive Treatment In Stable Pregnant Women With Severe Pre-Eclampsia (Metildopape) Unknown status NCT01361425 Phase 4 methildopa;placebo
2 Cardiovascular and Autonomic Reactivity in Women With a History of Pre-eclampsia Unknown status NCT00117546 Phase 4 alpha methyldopa
3 Low Dose Calcium to Prevent Preeclampsia Unknown status NCT02338687 Phase 4
4 Remifentanil for General Anesthesia in Preeclamptics Unknown status NCT00567957 Phase 4 Remifentanil;Saline
5 Pharmacokinetics of Amlodipine Besylate at Delivery and During Lactation Unknown status NCT02353806 Phase 4 Amlodipine besylate
6 Metformin and Gestational Diabetes in High-risk Patients: a RCTs Unknown status NCT00883259 Phase 4 Metformin
7 Prevention of Pre-eclampsia and SGA by Low-Dose Aspirin in Nulliparous Women With Abnormal First-trimester Uterine Artery Dopplers Completed NCT01729468 Phase 4 Aspirin;Placebo
8 Trial of Early Screening Test for Pre-eclampsia and Growth Restriction Completed NCT03674606 Phase 4 Low dose aspirin
9 Effects of Magnesium Sulphate on Sugammadex Reversal of Rocuronium Induced Blockade in Gynaecology Patients Completed NCT01972659 Phase 4 placebo;Magnesium Sulphate;sugammadex
10 The Effect of Ibuprofen on Post-partum Blood Pressure in Women With Hypertensive Disorders of Pregnancy Completed NCT02891174 Phase 4 Ibuprofen;Acetaminophen
11 Diuretics for Postpartum High Blood Pressure in Preeclampsia Completed NCT02163655 Phase 4 FUROSEMIDE;Placebo
12 Treatment Approaches to Preeclampsia Completed NCT01030627 Phase 4
13 Effectiveness Study of Short Course of Magnesium Sulfate for Severe Preeclamsia Completed NCT01408979 Phase 4 Magnesium sulfate 12 hours;Magnesium sulfate 24 hours
14 Comparison of Doses of Acetylsalicylic Acid in Women With Previous History of Preeclampsia Completed NCT01352234 Phase 4 Acetylsalicylic Acid 160 mg;Acetylsalicylic Acid 80 mg
15 Low Molecular Weight Heparin in Recurrent Miscarriage With Negative Antiphospholipid Antibodies Completed NCT01608347 Phase 4 LMWH+Folic acid;Folic Acid
16 Adding MgSO4 to Epidural Levobupivacaine in CS for Patients With Preeclampsia Completed NCT02699827 Phase 4 Levobupivacaine hydrochloride;Magnesium sulphate;Saline 0.9%
17 A Trial Comparing Treatment With the Springfusor Infusion Pump to the IV Magnesium Sulfate Regimen Completed NCT02091401 Phase 4 Magnesium Sulfate
18 Clonidine Versus Captopril for Treatment of Postpartum Very High Blood Pressure Completed NCT01761916 Phase 4 CLONIDINE;CAPTOPRIL
19 Oral Antihypertensive Regimens for Management of Hypertension in Pregnancy Completed NCT01912677 Phase 4 Nifedipine;Labetalol;Methyldopa
20 Metformin Versus Insulin in Gestational Diabetes Completed NCT01240785 Phase 4 metformin;insulin
21 Efficacy of Corifollitropin Alfa Versus Follitropin Beta in Aged IVF (In-vitro Fertilization) Patients Completed NCT02466204 Phase 4 corifollitropin alfa;Follitropin Beta
22 Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' Boostrix™ Vaccine in Pregnant Women Completed NCT02377349 Phase 4 Saline placebo
23 Phenylephrine Versus Ephedrine in Pre-eclampsia Recruiting NCT02025426 Phase 4 Phenylephrine;Ephedrine
24 Efficacy and Safety of 1 g Vs 2 g Per Hour Intravenous Maintenance Dose of MgSO4 in Women With Severe Pre-eclampsia Recruiting NCT03164304 Phase 4 Magnesium Sulfate
25 Impact of Antichlamydial Treatment on the Rate of Preeclampsia Recruiting NCT03233880 Phase 4 Azithromycin 1gm
26 Early Vascular Adjustments During Hypertensive Pregnancy Recruiting NCT02531490 Phase 4 Labetalol;Nifedipine;Methyldopa
27 Oral Nifedipine Versus Labetalol in Treatment of Postpartum Hypertension Recruiting NCT03449277 Phase 4 Oral Tablet
28 A Randomized Control Trial of Vitamin D Prophylaxis in the Prevention of Hypertensive Disorders of Pregnancy Recruiting NCT02920593 Phase 4 Vitamin D3
29 Response to Anti-hypertensives in Pregnant and Postpartum Patients Recruiting NCT03506724 Phase 4 Nifedipine;Labetalol
30 Is Procardia XL 60 mg Q Daily Equivalent to 30 mg XL Given Twice Daily? Recruiting NCT03595982 Phase 4 Procardia XL 30Mg;Procardia XL 60Mg
31 Continued Versus Discontinued Oxytocin Stimulation of Labour Recruiting NCT02553226 Phase 4 Oxytocin;Placebo
32 Chronic Hypertension and Pregnancy (CHAP) Project Recruiting NCT02299414 Phase 4 Anti-hypertensive therapy
33 Effect of Acetaminophen on Postpartum Blood Pressure Control in Preeclampsia With Severe Features Active, not recruiting NCT02911701 Phase 4 Acetaminophen;Ibuprofen
34 Contraception in Women With Sickle Cell Disease Active, not recruiting NCT02594462 Phase 4 etonogestrel-releasing implant contraceptive
35 The Effect of Two Aspirin Dosing Strategies for Obese Women at High Risk for Preeclampsia Not yet recruiting NCT03735433 Phase 4 162mg aspirin dose
36 Discontinuation of Magnesium Sulfate After Delivery in Women With Severe Preeclampsia. A Randomized Controlled Trial Not yet recruiting NCT03318211 Phase 4 Magnesium Sulfate
37 Effect of Administering Intravenous Magnesium Sulfate on Fetal Cardiotocography and Neonatal Outcome in Preeclamptic Patients Not yet recruiting NCT03237000 Phase 4 MgSO4
38 Metformin Use to Improve Pregnancy Outcome in Women With Type 1 Diabetes. Not yet recruiting NCT03765359 Phase 4 metforminhydrochloride;Placebo Oral Tablet
39 Metformin for Preeclampsia Prevention in Pregnant Women With Type 1 Diabetes Mellitus Not yet recruiting NCT03570632 Phase 4 Metformin
40 Different Schemes of Magnesium Sulfate for Preeclampsia Terminated NCT02396030 Phase 4 Magnesium sulfate 50% - 1g/h;Magnesium sulfate 50% - 2g/h
41 Atenativ Effect on Uterine Blood Flow and Preeclampsia Withdrawn NCT02278575 Phase 4 Atenativ
42 Investigating the Novel Observation of Right-Left Difference in Uterine Artery Vascular Resistance in Pre-Eclampsia Unknown status NCT00848679 Phase 3 Epidural lidocaine;Epidural lidocaine 2%
43 Treatment of Severe Hypertension During Pre-Eclampsia: A Preliminary Equivalence Study Between Urapidil and Nicardipine Unknown status NCT00409253 Phase 3 URAPIDIL (EUPRESSYL*);NICARDIPINE
44 Prospects for the Prevention of Pregnancy-induced Hypertension and Preeclampsia Trial Unknown status NCT02007837 Phase 3 Combined aspirin and multinutrient supplement
45 A Randomized Trial of Docosahexaenoic Acid Supplementation During Pregnancy to Prevent Deep Placentation Disorders Unknown status NCT02336243 Phase 3
46 Carbetocin vs. Oxytocin for Prevention of Postpartum Bleeding in Patients With Severe Preeclampsia Unknown status NCT01382732 Phase 3 Carbetocin;Oxytocin
47 A Randomized Clinical Trial of Oral Magnesium Supplementation in Pregnancy Unknown status NCT02032186 Phase 3 Magnesium citrate
48 Low Dose Aspirin for the Prevention of Preeclampsia Unknown status NCT01890005 Phase 3 Aspirin;Placebo
49 PP13 and Doppler Study to Predict Preeclampsia Unknown status NCT00928213 Phase 2, Phase 3 Progesterone;Low molecular weight Heparin;No Drug
50 Folic Acid Dosage and Malformations Reduction Unknown status NCT01244347 Phase 3 folic acid;folic acid

Search NIH Clinical Center for Eclampsia

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: eclampsia

Genetic Tests for Eclampsia

Genetic tests related to Eclampsia:

# Genetic test Affiliating Genes
1 Eclampsia 29

Anatomical Context for Eclampsia

MalaCards organs/tissues related to Eclampsia:

41
Endothelial, Placenta, Testes, Kidney, Heart, Liver, Brain

Publications for Eclampsia

Articles related to Eclampsia:

(show top 50) (show all 2766)
# Title Authors Year
1
Placental Elasticity as a New Non-invasive Predictive Marker of Pre-eclampsia. ( 30342781 )
2019
2
Maternal serum uric acid concentration and pregnancy outcomes in women with pre-eclampsia/eclampsia. ( 30353543 )
2019
3
Neutrophil-to-lymphocyte ratio and platelet indices in pre-eclampsia. ( 30362112 )
2019
4
Profound bilateral post-partum retinal circulation ischemia in two diabetic mothers with pre-eclampsia. ( 30519670 )
2019
5
Assessing the effect of dexmedetomidine in patients with pre-eclampsia. ( 30520788 )
2019
6
Nocturnal hypertension in high-risk mid-pregnancies predict the development of preeclampsia/eclampsia. ( 30015756 )
2019
7
Toll-like receptors signaling network in pre-eclampsia: An updated review. ( 30221394 )
2019
8
Is it time to move towards non-invasive prenatal screening for Down syndrome and screening for pre-eclampsia? ( 29446241 )
2018
9
Hemoglobin levels during the first trimester of pregnancy are associated with the risk of gestational diabetes mellitus, pre-eclampsia and preterm birth in Chinese women: a retrospective study. ( 29940874 )
2018
10
The feasibility of task-sharing the identification, emergency treatment, and referral for women with pre-eclampsia by community health workers in India. ( 29945662 )
2018
11
Maternal cardiac output response to colloid preload and vasopressor therapy during spinal anaesthesia for caesarean section in patients with severe pre-eclampsia: a randomised, controlled trial. ( 29086911 )
2018
12
Induction of systemic inflammation by hyaluronan and hsp70 in women with pre-eclampsia. ( 29438905 )
2018
13
Pre-Eclampsia and Eclampsia: An Update on the Pharmacological Treatment Applied in Portugal. ( 29367581 )
2018
14
Quality assessment of uterine artery Doppler measurement in first trimester combined screening for pre-eclampsia. ( 29917286 )
2018
15
Recurrence of pre-eclampsia and the risk of future hypertension and cardiovascular disease: a systematic review and meta-analysis. ( 29978553 )
2018
16
Screening for pre-eclampsia at 35-37 weeks' gestation. ( 29896778 )
2018
17
Elabela-APJ axis contributes to embryonic development and prevents pre-eclampsia in pregnancy. ( 29342224 )
2018
18
Decidual regulation of trophoblast is altered in pregnancies at risk of pre-eclampsia. ( 29437882 )
2018
19
Measurement of area difference ratio of Photoplethysmographic pulse wave in patients with pre-eclampsia. ( 29970018 )
2018
20
Streptococcus pyogenes subdural empyema and pre-eclampsia. ( 29582773 )
2018
21
Associations between the timing and dosing of aspirin prophylaxis and term and preterm pre-eclampsia. ( 29880699 )
2018
22
Associations of polymorphisms of CYP2D6 and CYP2C9 with early onset severe pre-eclampsia and response to labetalol therapy. ( 29789925 )
2018
23
A case of partial hydatidiform molar pregnancy with a placental diploid-triploid mosaicism associated with a euploid viable foetus complicated with severe pre-eclampsia. ( 29421928 )
2018
24
Up-regulation of miR-299 suppressed the invasion and migration of HTR-8/SVneo trophoblast cells partly via targeting HDAC2 in pre-eclampsia. ( 29145147 )
2018
25
Three-dimensional indices of renal perfusion in normal pregnancy and pre-eclampsia. ( 29916133 )
2018
26
A computerized algorithm to capture patient's past preeclampsia and eclampsia history from prenatal clinical notes. ( 29388496 )
2018
27
Combination of first trimester serum afamin levels and three-dimensional placental bed vascularization as a possible screening method to detect women at-risk for adverse pregnancy complications like pre-eclampsia and gestational diabetes mellitus in low-risk pregnancies. ( 29405972 )
2018
28
Study on the correlation between adipocyte fatty-acid binding protein, glucolipid metabolism, and pre-eclampsia. ( 29316087 )
2018
29
Utility of serology in the diagnosis of pre-eclampsia and haemolytic uraemic syndrome in pregnancy-related acute kidney injury. ( 29890047 )
2018
30
Screening for pre-eclampsia by maternal factors and biomarkers at 11-13a88weeks' gestation. ( 29896812 )
2018
31
Re: Placental histopathology associated with pre-eclampsia: a systematic review and meta-analysis. ( 29417682 )
2018
32
Prediction and prevention of pre-eclampsia in Asian subpopulation. ( 29442407 )
2018
33
HLA-DR is aberrantly expressed at feto-maternal interface in pre-eclampsia. ( 29941324 )
2018
34
Are women with history of pre-eclampsia starting a new pregnancy in good nutritional status in South Africa and Zimbabwe? ( 29907146 )
2018
35
Baseline check of blood pressure readings of an automated device in severe pre-eclampsia and healthy normotensive pregnancy. ( 29674198 )
2018
36
Association between fetal fraction on cell-free DNA testing and first trimester markers for pre-eclampsia. ( 29318732 )
2018
37
Effect of blood pressure on reversible posterior leukoencephalopathy syndrome in pre-eclampsia or eclampsia. ( 29093565 )
2018
38
Prediction of pre-eclampsia and its subtypes in high-risk cohort: hyperglycosylated human chorionic gonadotropin in multivariate models. ( 29970026 )
2018
39
Pre-eclampsia and the risk of autism-spectrum disorder in offspring: meta-analysis. ( 29436313 )
2018
40
Dexmedetomidine as a part of general anaesthesia for caesarean delivery in patients with pre-eclampsia: Efficacy and foetal outcome: a randomised double-blinded trial. ( 29432379 )
2018
41
The potential therapeutic effects of ergothioneine in pre-eclampsia. ( 29284116 )
2018
42
Int6/eIF3e Silencing Promotes Placenta Angiogenesis in a Rat Model of Pre-eclampsia. ( 29895936 )
2018
43
Serum amyloid A, procalcitonin, highly sensitive C reactive protein and tumor necrosis factor alpha levels and acute inflammatory response in patients with hemolysis, elevated liver enzymes, low platelet count (HELLP) and eclampsia. ( 29345041 )
2018
44
Molar pregnancy with normal viable fetus presenting with severe pre-eclampsia: a case report. ( 29779493 )
2018
45
Severe tricuspid regurgitation and seizure on postpartum day 10: case report of late postpartum eclampsia. ( 29451101 )
2018
46
LncRNA PRNCR1 promoted the progression of eclampsia by regulating the MAPK signal pathway. ( 29949134 )
2018
47
Pre-eclampsia affects procalcitonin production in placental tissue. ( 29427369 )
2018
48
Pre-Eclampsia: A Twilight Zone Between Health and Cardiovascular Disease? ( 29957220 )
2018
49
Twin gestation in a Swyer syndrome patient with superimposed pre-eclampsia. ( 29421927 )
2018
50
Changes in the Expression of AQP4 and AQP9 in the Hippocampus Following Eclampsia-Like Seizure. ( 29351212 )
2018

Variations for Eclampsia

Expression for Eclampsia

Search GEO for disease gene expression data for Eclampsia.

Pathways for Eclampsia

Pathways related to Eclampsia according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
10.16 FLT1 PGF
2 9.8 EPHX1 F2

GO Terms for Eclampsia

Cellular components related to Eclampsia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.7 ALB CORIN EDN1 F2 FLT1 HLA-G
2 extracellular space GO:0005615 9.36 ALB EDN1 ENG F2 FLT1 INHBB

Biological processes related to Eclampsia according to GeneCards Suite gene sharing:

(show all 13)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 9.88 EDN1 F2 FLT1 PGF STOX1
2 response to drug GO:0042493 9.83 EDN1 ENG MTHFR PGF
3 regulation of signaling receptor activity GO:0010469 9.65 EDN1 F2 INHBB OXT PGF
4 vascular endothelial growth factor signaling pathway GO:0038084 9.51 FLT1 PGF
5 negative regulation of blood coagulation GO:0030195 9.49 EDN1 THBD
6 positive regulation of renal sodium excretion GO:0035815 9.46 EDN1 OXT
7 regulation of blood coagulation GO:0030193 9.43 F2 SERPINC1
8 response to transforming growth factor beta GO:0071559 9.4 EDN1 ENG
9 negative regulation of fibrinolysis GO:0051918 9.37 F2 THBD
10 negative regulation of platelet activation GO:0010544 9.32 F2 THBD
11 positive regulation of prostaglandin secretion GO:0032308 9.16 EDN1 OXT
12 hemostasis GO:0007599 9.13 F2 SERPINC1 THBD
13 female pregnancy GO:0007565 9.02 CORIN OXT PGF TAC3 THBD

Molecular functions related to Eclampsia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 8.8 EDN1 INHBB OXT

Sources for Eclampsia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....