Aliases & Classifications for Ecthyma

MalaCards integrated aliases for Ecthyma:

Name: Ecthyma 12 44 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:11907
MeSH 44 D004473
SNOMED-CT 68 85791004
UMLS 73 C0013568

Summaries for Ecthyma

MalaCards based summary : Ecthyma is related to aplastic anemia and lymphoma, non-hodgkin, familial. An important gene associated with Ecthyma is RDH11 (Retinol Dehydrogenase 11), and among its related pathways/superpathways are ERK Signaling and Akt Signaling. Affiliated tissues include skin, kidney and bone, and related phenotypes are hematopoietic system and immune system

Wikipedia : 76 Ecthyma is a variation of impetigo, presenting at a deeper level of... more...

Related Diseases for Ecthyma

Diseases related to Ecthyma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 103)
# Related Disease Score Top Affiliating Genes
1 aplastic anemia 28.6 CSF2 CSF3 GATA3 TBX21
2 lymphoma, non-hodgkin, familial 27.3 ALK CSF2 CSF3 TNFRSF8
3 contagious pustular dermatitis 11.9
4 lichen planus pemphigoides 10.8 COL17A1 DST
5 pemphigoid gestationis 10.8 COL17A1 DST
6 agammaglobulinemia, non-bruton type 10.7 BTK CD79B
7 linear iga disease 10.7 COL17A1 DST
8 herpes gestationis 10.6 COL17A1 DST
9 erythema elevatum diutinum 10.5 GATA3 TBX21
10 hypoparathyroidism, sensorineural deafness, and renal disease 10.5 GATA3 LAMB2
11 neurotic excoriation 10.5 COL17A1 DST KCNJ11
12 polyclonal hypergammaglobulinemia 10.4 CD4 MYOM2
13 cerebellopontine angle meningioma 10.3 KANTR SAMHD1
14 accommodative esotropia 10.2 KANTR SAMHD1
15 facial hemiatrophy 10.1 COL17A1 KANTR
16 bronchial disease 10.1 CSF2 GATA3 STAT6
17 leukemia 10.1
18 neutropenia 10.0
19 factitious disorder 9.9 KANTR KCNJ11
20 cellulitis 9.9
21 engraftment syndrome 9.9 CSF2 CSF3
22 trichosporonosis 9.9 CSF2 CSF3
23 dermatitis 9.8
24 pyoderma 9.8
25 pneumonia 9.8
26 felty syndrome 9.8 CSF2 CSF3
27 leukemia, acute lymphoblastic 9.8
28 pulmonary fibrosis and/or bone marrow failure, telomere-related, 2 9.8
29 acute leukemia 9.8
30 burns 9.8
31 fusariosis 9.8
32 lymphoma 9.8
33 lymphoblastic leukemia 9.8
34 lymphadenitis 9.8
35 agammaglobulinemia 9.8
36 astrocytoma 9.8
37 acquired immunodeficiency syndrome 9.8
38 impetigo 9.8
39 pyoderma gangrenosum 9.8
40 paraphimosis 9.7 KANTR TNFRSF8
41 immune system disease 9.7 COL17A1 CSF2 CSF3
42 cochlear disease 9.6 GATA3 KANTR
43 leukocyte adhesion deficiency, type i 9.6
44 systemic lupus erythematosus 9.6
45 rheumatoid arthritis 9.6
46 lymphoma, hodgkin, classic 9.6
47 methylmalonic aciduria, cblb type 9.6
48 moyamoya disease 1 9.6
49 mycosis fungoides 9.6
50 myelofibrosis 9.6

Graphical network of the top 20 diseases related to Ecthyma:



Diseases related to Ecthyma

Symptoms & Phenotypes for Ecthyma

MGI Mouse Phenotypes related to Ecthyma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.96 BTK CD4 CD79B CSF2 CSF3 FGF2
2 immune system MP:0005387 9.9 TBX21 TNFRSF8 BTK CD4 CD79B CSF2
3 integument MP:0010771 9.61 ALK BTK CD4 CSF2 CSF3 GATA3
4 neoplasm MP:0002006 9.1 ALK BTK CSF2 FGF2 STAT6 TBX21

Drugs & Therapeutics for Ecthyma

Search Clinical Trials , NIH Clinical Center for Ecthyma

Cochrane evidence based reviews: ecthyma

Genetic Tests for Ecthyma

Anatomical Context for Ecthyma

MalaCards organs/tissues related to Ecthyma:

41
Skin, Kidney, Bone, Testes, Neutrophil, Myeloid, Liver

Publications for Ecthyma

Articles related to Ecthyma:

(show top 50) (show all 337)
# Title Authors Year
1
Orf (ecthyma contagiosum) in a sheep and a shepherd. ( 29303728 )
2018
2
Ecthyma gangrenosum, an important cutaneous infection to recognize in the immunosuppressed patient. ( 29058333 )
2018
3
Phylogenetic Analysis of ORF Viruses From Five Contagious Ecthyma Outbreaks in Argentinian Goats. ( 29971243 )
2018
4
Ecthyma Gangrenosum: Vulvar Ulcers, Pseudomonas and Pancytopenia, A Case Report of an 18- Month-Old Female. ( 29885367 )
2018
5
Non-pseudomonal Ecthyma Gangrenosum and Idiopathic Myelofibrosis in a Two-Year-Old Girl. ( 29881654 )
2018
6
Molecular identification and investigations of contagious ecthyma (Orf virus) in small ruminants, North west Ethiopia. ( 29334948 )
2018
7
One Thing after Another: Ecthyma Gangrenosum. ( 29371156 )
2018
8
Ecthyma gangrenosum, a skin manifestation of Pseudomonas aeruginosa sepsis in a previously healthy child: A case report. ( 28079790 )
2017
9
Pasteurella multocida ecthyma complicated by necrotizing fasciitis. ( 28541874 )
2017
10
Ecthyma gangrenosum: a report of eight cases. ( 29166510 )
2017
11
Ecthyma Gangrenosum in the Eyelid. ( 29084109 )
2017
12
Ecthyma gangrenosum caused by Citrobacter freundii. ( 28751433 )
2017
13
Ecthyma Gangrenosum: Escherichia coli or Pseudomonas aeruginosa? ( 28611752 )
2017
14
Ecthyma Gangrenosum. ( 29211664 )
2017
15
Ecthyma gangrenosum in a 3-month-old, previously healthy infant: A Case Report. ( 28272221 )
2017
16
Non-pseudomonal ecthyma gangrenosum caused by methicillin-resistant Staphylococcus aureus (MRSA) in a chronic alcoholic patient. ( 28775089 )
2017
17
Ecthyma gangrenosum as first manifestation of acute leukemia. ( 28736062 )
2017
18
Ecthyma gangrenosum in a case of acute lymphoblastic lymphoma. ( 28052953 )
2017
19
Identification and phylogenetic analysis of contagious ecthyma virus from camels (<i>Camelus dromedarius</i>) in Iran. ( 28397518 )
2017
20
Wife to husband transmission of Ecthyma contagiosum (Orf). ( 28560176 )
2017
21
Ecthyma gangrenosum without bacteraemia: evidence in favour of a broader definition. ( 28239902 )
2017
22
Ecthyma associated with Moraxella and Staphylococcus epidermidis. ( 27981222 )
2016
23
Orf virus infection in human ecthyma contagiosum: a report of two cases in the West of Iran. ( 27366776 )
2016
24
Ecthyma gangrenosum in the periorbital region in a previously healthy immunocompetent woman without bacteremia. ( 26955586 )
2016
25
Disseminated Candida tropicalis presenting with Ecthyma-Gangrenosum-like Lesions. ( 26990472 )
2016
26
Ecthyma gangrenosum of the scrotum: a case report. ( 26941196 )
2016
27
Case of ecthyma gangrenosum in which only methicillin-resistant Staphylococcus epidermidis was detected. ( 26703091 )
2016
28
Ecthyma gangrenosum in a renal transplant recipient. ( 27493006 )
2016
29
Dermoscopy of contagious ecthyma (orf nodule). ( 27085247 )
2016
30
Ecthyma gangrenosum in an infant after liver transplantation. ( 27682614 )
2016
31
Seroprevalence of contagious ecthyma in goats of Assam: An analysis by indirect enzyme-linked immunosorbent assay. ( 27733808 )
2016
32
Tularemia Masquerading as Ecthyma. ( 27562918 )
2016
33
An Extraordinary Cause of the Sucking Difficulty: Ecthyma Gangrenosum. ( 27143976 )
2016
34
A case of perineal ecthyma gangrenosum. ( 27103864 )
2016
35
Ecthyma gangrenosum secondary to methicillin-sensitive Staphylococcus aureus. ( 28492017 )
2016
36
The Concept of Ecthyma Gangrenosum Illustrated by a Fusarium oxysporum Infection in an Immunocompetent Individual. ( 27324372 )
2016
37
Atypical case of ecthyma gangrenosum mimicking a breast cancer recurrence. ( 27030458 )
2016
38
Ecthyma gangrenosum-like lesions in a case of disseminated Mycobacterium tuberculosis in a renal transplant recipient. ( 27727755 )
2016
39
Occurrence and identification of contagious ecthyma in blackbuck. ( 27366773 )
2016
40
Contagious Ecthyma, Rangiferine Brucellosis, and Lungworm Infection in a Muskox ( Ovibos moschatus ) from the Canadian Arctic, 2014. ( 27285415 )
2016
41
Nonpseudomonal ecthyma gangrenosum of the upper lid treated with lid reconstruction. ( 26655009 )
2015
42
Colostomy for Perianal Sepsis With Ecthyma Gangrenosum in Immunocompromised Children. ( 25757025 )
2015
43
Ecthyma gangrenosum skin lesions in previously healthy children. ( 25469722 )
2015
44
Ecthyma Gangrenosum Caused by Escherichia coli in a Previously Healthy Girl. ( 25940214 )
2015
45
Rapid detection of contagious ecthyma by loop-mediated isothermal amplification and epidemiology in Jilin Province China. ( 26346652 )
2015
46
Phylogenetic analysis of eight sudanese camel contagious ecthyma viruses based on B2L gene sequence. ( 26260127 )
2015
47
Ecthyma gangrenosum versus ecthyma-like lesions: should we separate these conditions? ( 26697730 )
2015
48
Calciphylaxis and Ecthyma Gangrenosum in Chronic Kidney Disease: Clinical Similarities. ( 25912956 )
2015
49
A Rare Case of Ecthyma Gangrenosum Caused by Proteus vulgaris and Candida albicans in a Patient with Castleman Disease. ( 26618137 )
2015
50
Connubial ecthyma gangrenosum in a healthy couple: a consort counterpart of a "kissing ulcer". ( 25770307 )
2015

Variations for Ecthyma

Expression for Ecthyma

Search GEO for disease gene expression data for Ecthyma.

Pathways for Ecthyma

Pathways related to Ecthyma according to GeneCards Suite gene sharing:

(show all 16)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.6 ALK BTK CD4 COL17A1 CSF2 CSF3
2
Show member pathways
13.07 ALK BTK CD4 CSF2 CSF3 FGF2
3
Show member pathways
12.87 CD4 CSF2 CSF3 FGF2 GATA3 SAMHD1
4
Show member pathways
12.43 CSF2 CSF3 SAMHD1 STAT6
5
Show member pathways
12.23 CD4 GATA3 STAT6 TBX21
6 12.17 BTK GATA3 STAT6 TBX21 TNFRSF8
7 11.79 FGF2 GATA3 STAT6
8
Show member pathways
11.78 CD4 STAT6 TBX21
9 11.69 CD4 CSF2 CSF3
10 11.58 CSF2 GATA3 TBX21
11 11.56 CD4 GATA3 TBX21
12
Show member pathways
11.51 CSF2 GATA3 TBX21
13 11.38 CSF2 CSF3 FGF2
14 11.32 CD4 CD79B CSF2 CSF3
15 11.21 CD4 GATA3 STAT6
16 10.28 CD4 CSF2 CSF3

GO Terms for Ecthyma

Cellular components related to Ecthyma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 basement membrane GO:0005604 9.13 COL17A1 DST LAMB2
2 hemidesmosome GO:0030056 8.62 COL17A1 DST

Biological processes related to Ecthyma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peptidyl-tyrosine phosphorylation GO:0018108 9.71 ALK BTK CSF2 FGF2
2 immune response GO:0006955 9.63 CD4 CD79B CSF2 CSF3 SAMHD1 TNFRSF8
3 negative regulation of interleukin-2 production GO:0032703 9.46 GATA3 TBX21
4 cellular response to granulocyte macrophage colony-stimulating factor stimulus GO:0097011 9.43 CD4 CSF2
5 T cell differentiation GO:0030217 9.43 CD4 GATA3 TBX21
6 lymphocyte migration GO:0072676 9.37 GATA3 TBX21
7 regulation of cell proliferation GO:0042127 9.35 ALK BTK CSF2 STAT6 TNFRSF8
8 neutrophil differentiation GO:0030223 9.32 CSF2 CSF3
9 cytokine-mediated signaling pathway GO:0019221 9.1 CD4 CSF2 CSF3 FGF2 GATA3 STAT6

Molecular functions related to Ecthyma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.63 ALK BTK CD4 CD79B SAMHD1 STAT6
2 integrin binding GO:0005178 9.13 DST FGF2 LAMB2
3 protein tyrosine kinase activity GO:0004713 8.92 ALK BTK CSF2 FGF2

Sources for Ecthyma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....