Aliases & Classifications for Ecthyma

MalaCards integrated aliases for Ecthyma:

Name: Ecthyma 12 45 15 17 74

Classifications:



External Ids:

Disease Ontology 12 DOID:11907
MeSH 45 D004473
SNOMED-CT 69 85791004
UMLS 74 C0013568

Summaries for Ecthyma

MalaCards based summary : Ecthyma is related to aplastic anemia and lymphoma, non-hodgkin, familial. An important gene associated with Ecthyma is RDH11 (Retinol Dehydrogenase 11), and among its related pathways/superpathways are ERK Signaling and Akt Signaling. Affiliated tissues include skin, kidney and bone, and related phenotypes are neoplasm and vision/eye

Wikipedia : 77 Ecthyma is a variation of impetigo, presenting at a deeper level of... more...

Related Diseases for Ecthyma

Diseases related to Ecthyma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 106)
# Related Disease Score Top Affiliating Genes
1 aplastic anemia 29.4 CSF2 CSF3 GATA3 TBX21
2 lymphoma, non-hodgkin, familial 28.6 ALK CSF2 CSF3 MYOM2 TNFRSF8
3 contagious pustular dermatitis 12.1
4 pyoderma 11.4
5 lichen planus pemphigoides 10.4 COL17A1 DST
6 pemphigoid gestationis 10.3 COL17A1 DST
7 agammaglobulinemia, non-bruton type 10.3 BTK CD79B
8 linear iga disease 10.3 COL17A1 DST
9 neurotic excoriation 10.3 COL17A1 DST
10 leukemia 10.3
11 plasma protein metabolism disease 10.3 BTK CD79B MYOM2
12 hypoparathyroidism, sensorineural deafness, and renal disease 10.3 GATA3 LAMB2
13 waldenstroem's macroglobulinemia 10.3 BTK MYOM2
14 subcorneal pustular dermatosis 10.2 COL17A1 DST MYOM2
15 erythema elevatum diutinum 10.2 GATA3 TBX21
16 neutropenia 10.2
17 facial hemiatrophy 10.2 COL17A1 KANTR
18 cellulitis 10.1
19 cochlear disease 10.1 GATA3 KANTR
20 bronchial disease 10.1 CSF2 GATA3 STAT6
21 acute leukemia 10.0
22 lymphocytic leukemia 10.0
23 dermatitis 10.0
24 acquired immunodeficiency syndrome 10.0
25 engraftment syndrome 10.0 CSF2 CSF3
26 trichosporonosis 10.0 CSF2 CSF3
27 gastric signet ring cell adenocarcinoma 10.0 FGF2 GATA3
28 felty syndrome 10.0 CSF2 CSF3
29 leukemia, acute myeloid 9.9
30 leukemia, acute lymphoblastic 9.9
31 pulmonary fibrosis and/or bone marrow failure, telomere-related, 2 9.9
32 fusariosis 9.9
33 lymphoma 9.9
34 lymphadenitis 9.9
35 agammaglobulinemia 9.9
36 astrocytoma 9.9
37 pneumonia 9.9
38 impetigo 9.9
39 pyoderma gangrenosum 9.9
40 myeloid leukemia 9.9
41 noma 9.9
42 poems syndrome 9.9 FGF2 MYOM2
43 paraphimosis 9.8 KANTR TNFRSF8
44 colon lymphoma 9.8 ALK TNFRSF8
45 embryoma 9.8 GATA3 TNFRSF8
46 breast cancer 9.8
47 leukocyte adhesion deficiency, type i 9.8
48 systemic lupus erythematosus 9.8
49 rheumatoid arthritis 9.8
50 lymphoma, hodgkin, classic 9.8

Graphical network of the top 20 diseases related to Ecthyma:



Diseases related to Ecthyma

Symptoms & Phenotypes for Ecthyma

MGI Mouse Phenotypes related to Ecthyma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 9.43 ALK BTK CSF2 FGF2 STAT6 TBX21
2 vision/eye MP:0005391 9.17 ALK FGF2 GATA3 KIDINS220 LAMB2 RDH11

Drugs & Therapeutics for Ecthyma

Search Clinical Trials , NIH Clinical Center for Ecthyma

Cochrane evidence based reviews: ecthyma

Genetic Tests for Ecthyma

Anatomical Context for Ecthyma

MalaCards organs/tissues related to Ecthyma:

42
Skin, Kidney, Bone, Myeloid, Liver, Bone Marrow, Small Intestine

Publications for Ecthyma

Articles related to Ecthyma:

(show top 50) (show all 358)
# Title Authors Year
1
Fatal Oculocutaneous Ecthyma Gangrenosum in Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome: Case Report and Review of the Literature. ( 30814835 )
2019
2
Juvenile ecthyma gangrenosum caused by Pseudomonas aeruginosa revealing an underlying neutropenia: case report and review of the literature. ( 30633375 )
2019
3
Hairy cell leukemia presenting with Ecthyma Gangrenosum- a case report. ( 30683071 )
2019
4
Outbreak of contagious ecthyma caused by Orf virus (Parapoxvirus ovis) in a vaccinated sheep flock in Uruguay. ( 30835059 )
2019
5
Orf (ecthyma contagiosum) in a sheep and a shepherd. ( 29303728 )
2018
6
Ecthyma gangrenosum, an important cutaneous infection to recognize in the immunosuppressed patient. ( 29058333 )
2018
7
Phylogenetic Analysis of ORF Viruses From Five Contagious Ecthyma Outbreaks in Argentinian Goats. ( 29971243 )
2018
8
Ecthyma Gangrenosum: Vulvar Ulcers, Pseudomonas and Pancytopenia, A Case Report of an 18- Month-Old Female. ( 29885367 )
2018
9
Non-pseudomonal Ecthyma Gangrenosum and Idiopathic Myelofibrosis in a Two-Year-Old Girl. ( 29881654 )
2018
10
Molecular identification and investigations of contagious ecthyma (Orf virus) in small ruminants, North west Ethiopia. ( 29334948 )
2018
11
One Thing after Another: Ecthyma Gangrenosum. ( 29371156 )
2018
12
Septic shock related to community-acquired pneumonia with ecthyma gangrenosum. ( 30528272 )
2018
13
Successful Use of Negative-pressure Wound Therapy and Dermal Substitute in the Treatment of Gluteal Ecthyma Gangrenosum in a 2-year-old Girl. ( 30534498 )
2018
14
Ecthyma gangrenosum caused by Klebsiella pneumoniae and Streptococcus vestibularis in a patient with acute myeloid leukemia: an emerging pathogen. ( 30548464 )
2018
15
Concomitant diagnosis of immune deficiency and Pseudomonas sepsis in a 19 month old with ecthyma gangrenosum by host whole-genome sequencing. ( 30559311 )
2018
16
Ecthyma gangrenosum on the face of a malnourished child with Pseudomonas sepsis: Simulating Cancrum oris. ( 30568894 )
2018
17
Ecthyma contagiosum (Orf): Reflectance confocal microscopy and histopathological correlates. ( 30019407 )
2018
18
Ecthyma gangrenosum due to Pseudomonas fluorescens. ( 30138506 )
2018
19
Primary ecthyma gangraenosum due to central venous catheter-related bloodstream infection with Pseudomonas aeruginosa. ( 30187217 )
2018
20
Ecthyma Gangrenosum in Paroxysmal Nocturnal Hemoglobinuria. ( 30300881 )
2018
21
First report of camel contagious ecthyma in Nigeria. ( 30425954 )
2018
22
Clinical Manifestation, Dermoscopy, and Scanning Electron Microscopy in Two Cases of Contagious Ecthyma (Orf Nodule). ( 30510811 )
2018
23
Ecthyma gangrenosum, a skin manifestation of Pseudomonas aeruginosa sepsis in a previously healthy child: A case report. ( 28079790 )
2017
24
Pasteurella multocida ecthyma complicated by necrotizing fasciitis. ( 28541874 )
2017
25
Ecthyma gangrenosum: a report of eight cases. ( 29166510 )
2017
26
Ecthyma Gangrenosum in the Eyelid. ( 29084109 )
2017
27
Ecthyma gangrenosum caused by Citrobacter freundii. ( 28751433 )
2017
28
Ecthyma Gangrenosum: Escherichia coli or Pseudomonas aeruginosa? ( 28611752 )
2017
29
Ecthyma Gangrenosum. ( 29211664 )
2017
30
Ecthyma gangrenosum in a 3-month-old, previously healthy infant: A Case Report. ( 28272221 )
2017
31
Non-pseudomonal ecthyma gangrenosum caused by methicillin-resistant Staphylococcus aureus (MRSA) in a chronic alcoholic patient. ( 28775089 )
2017
32
Ecthyma gangrenosum as first manifestation of acute leukemia. ( 28736062 )
2017
33
Ecthyma gangrenosum in a case of acute lymphoblastic lymphoma. ( 28052953 )
2017
34
Identification and phylogenetic analysis of contagious ecthyma virus from camels (<i>Camelus dromedarius</i>) in Iran. ( 28397518 )
2017
35
Wife to husband transmission of Ecthyma contagiosum (Orf). ( 28560176 )
2017
36
Ecthyma gangrenosum without bacteraemia: evidence in favour of a broader definition. ( 28239902 )
2017
37
Ecthyma associated with Moraxella and Staphylococcus epidermidis. ( 27981222 )
2016
38
Orf virus infection in human ecthyma contagiosum: a report of two cases in the West of Iran. ( 27366776 )
2016
39
Ecthyma gangrenosum in the periorbital region in a previously healthy immunocompetent woman without bacteremia. ( 26955586 )
2016
40
Disseminated Candida tropicalis presenting with Ecthyma-Gangrenosum-like Lesions. ( 26990472 )
2016
41
Ecthyma gangrenosum of the scrotum: a case report. ( 26941196 )
2016
42
Case of ecthyma gangrenosum in which only methicillin-resistant Staphylococcus epidermidis was detected. ( 26703091 )
2016
43
Ecthyma gangrenosum in a renal transplant recipient. ( 27493006 )
2016
44
Dermoscopy of contagious ecthyma (orf nodule). ( 27085247 )
2016
45
Ecthyma gangrenosum in an infant after liver transplantation. ( 27682614 )
2016
46
Seroprevalence of contagious ecthyma in goats of Assam: An analysis by indirect enzyme-linked immunosorbent assay. ( 27733808 )
2016
47
Tularemia Masquerading as Ecthyma. ( 27562918 )
2016
48
An Extraordinary Cause of the Sucking Difficulty: Ecthyma Gangrenosum. ( 27143976 )
2016
49
A case of perineal ecthyma gangrenosum. ( 27103864 )
2016
50
Ecthyma gangrenosum secondary to methicillin-sensitive Staphylococcus aureus. ( 28492017 )
2016

Variations for Ecthyma

Expression for Ecthyma

Search GEO for disease gene expression data for Ecthyma.

Pathways for Ecthyma

GO Terms for Ecthyma

Cellular components related to Ecthyma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 basement membrane GO:0005604 9.13 COL17A1 DST LAMB2
2 hemidesmosome GO:0030056 8.62 COL17A1 DST

Biological processes related to Ecthyma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peptidyl-tyrosine phosphorylation GO:0018108 9.46 ALK BTK CSF2 FGF2
2 negative regulation of interleukin-2 production GO:0032703 9.32 GATA3 TBX21
3 hemidesmosome assembly GO:0031581 9.26 COL17A1 DST
4 cytokine-mediated signaling pathway GO:0019221 9.02 CSF2 CSF3 FGF2 GATA3 STAT6
5 lymphocyte migration GO:0072676 8.96 GATA3 TBX21

Molecular functions related to Ecthyma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 integrin binding GO:0005178 9.13 DST FGF2 LAMB2
2 protein tyrosine kinase activity GO:0004713 8.92 ALK BTK CSF2 FGF2

Sources for Ecthyma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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