Aliases & Classifications for Ecthyma

MalaCards integrated aliases for Ecthyma:

Name: Ecthyma 12 44 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:11907
MeSH 44 D004473
SNOMED-CT 68 85791004
UMLS 73 C0013568

Summaries for Ecthyma

MalaCards based summary : Ecthyma is related to aplastic anemia and lymphoma, non-hodgkin, familial. An important gene associated with Ecthyma is RDH11 (Retinol Dehydrogenase 11), and among its related pathways/superpathways are ERK Signaling and PAK Pathway. Affiliated tissues include skin, bone and kidney, and related phenotypes are hematopoietic system and endocrine/exocrine gland

Wikipedia : 76 Ecthyma is a variation of impetigo, presenting at a deeper level of... more...

Related Diseases for Ecthyma

Diseases related to Ecthyma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 107)
# Related Disease Score Top Affiliating Genes
1 aplastic anemia 29.5 CSF2 CSF3 GATA3 TBX21
2 lymphoma, non-hodgkin, familial 28.8 ALK CSF2 CSF3 MYOM2 TNFRSF8
3 contagious pustular dermatitis 12.1
4 pyoderma 11.4
5 lichen planus pemphigoides 10.2 COL17A1 DST
6 pemphigoid gestationis 10.2 COL17A1 DST
7 linear iga disease 10.2 COL17A1 DST
8 leukemia 10.2
9 herpes gestationis 10.2 COL17A1 DST
10 agammaglobulinemia, non-bruton type 10.2 BTK CD79B
11 plasma protein metabolism disease 10.2 BTK CD79B MYOM2
12 hypoparathyroidism, sensorineural deafness, and renal disease 10.2 GATA3 LAMB2
13 subcorneal pustular dermatosis 10.2 COL17A1 DST MYOM2
14 polyclonal hypergammaglobulinemia 10.2 CD4 MYOM2
15 waldenstroem's macroglobulinemia 10.1 BTK MYOM2
16 neurotic excoriation 10.1 COL17A1 DST KCNJ11
17 facial hemiatrophy 10.1 COL17A1 KANTR
18 erythema elevatum diutinum 10.1 GATA3 TBX21
19 neutropenia 10.1
20 cellulitis 10.1
21 cochlear disease 10.0 GATA3 KANTR
22 bronchial disease 10.0 CSF2 GATA3 STAT6
23 acute leukemia 10.0
24 lymphocytic leukemia 10.0
25 dermatitis 10.0
26 viral infectious disease 10.0
27 engraftment syndrome 10.0 CSF2 CSF3
28 trichosporonosis 10.0 CSF2 CSF3
29 felty syndrome 9.9 CSF2 CSF3
30 leukemia, acute myeloid 9.9
31 leukemia, acute lymphoblastic 9.9
32 pulmonary fibrosis and/or bone marrow failure, telomere-related, 2 9.9
33 fusariosis 9.9
34 lymphoma 9.9
35 lymphadenitis 9.9
36 agammaglobulinemia 9.9
37 astrocytoma 9.9
38 pneumonia 9.9
39 acquired immunodeficiency syndrome 9.9
40 impetigo 9.9
41 pyoderma gangrenosum 9.9
42 myeloid leukemia 9.9
43 paraphimosis 9.9 KANTR TNFRSF8
44 gastric signet ring cell adenocarcinoma 9.9 FGF2 GATA3
45 colon lymphoma 9.8 ALK TNFRSF8
46 embryoma 9.8 GATA3 TNFRSF8
47 hodgkin's lymphoma, lymphocytic depletion 9.8 ALK CSF2 TNFRSF8
48 breast cancer 9.8
49 leukocyte adhesion deficiency, type i 9.8
50 systemic lupus erythematosus 9.8

Graphical network of the top 20 diseases related to Ecthyma:



Diseases related to Ecthyma

Symptoms & Phenotypes for Ecthyma

MGI Mouse Phenotypes related to Ecthyma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.02 BTK CD4 CD79B CSF2 CSF3 FGF2
2 endocrine/exocrine gland MP:0005379 9.97 ALK CD4 CSF2 GATA3 KCNJ11 STAT6
3 immune system MP:0005387 9.96 BTK CD4 CD79B CSF2 CSF3 GATA3
4 integument MP:0010771 9.81 ALK BTK CD4 CSF2 CSF3 GATA3
5 neoplasm MP:0002006 9.43 ALK BTK CSF2 FGF2 STAT6 TBX21
6 nervous system MP:0003631 9.32 ALK CD4 CSF2 FGF2 GATA3 KCNJ11

Drugs & Therapeutics for Ecthyma

Search Clinical Trials , NIH Clinical Center for Ecthyma

Cochrane evidence based reviews: ecthyma

Genetic Tests for Ecthyma

Anatomical Context for Ecthyma

MalaCards organs/tissues related to Ecthyma:

41
Skin, Bone, Kidney, Myeloid, Breast, Bone Marrow, Thymus

Publications for Ecthyma

Articles related to Ecthyma:

(show top 50) (show all 352)
# Title Authors Year
1
Orf (ecthyma contagiosum) in a sheep and a shepherd. ( 29303728 )
2018
2
Ecthyma gangrenosum, an important cutaneous infection to recognize in the immunosuppressed patient. ( 29058333 )
2018
3
Phylogenetic Analysis of ORF Viruses From Five Contagious Ecthyma Outbreaks in Argentinian Goats. ( 29971243 )
2018
4
Ecthyma Gangrenosum: Vulvar Ulcers, Pseudomonas and Pancytopenia, A Case Report of an 18- Month-Old Female. ( 29885367 )
2018
5
Non-pseudomonal Ecthyma Gangrenosum and Idiopathic Myelofibrosis in a Two-Year-Old Girl. ( 29881654 )
2018
6
Molecular identification and investigations of contagious ecthyma (Orf virus) in small ruminants, North west Ethiopia. ( 29334948 )
2018
7
One Thing after Another: Ecthyma Gangrenosum. ( 29371156 )
2018
8
Ecthyma contagiosum (Orf): Reflectance confocal microscopy and histopathological correlates. ( 30019407 )
2018
9
Ecthyma gangrenosum due to Pseudomonas fluorescens. ( 30138506 )
2018
10
Primary ecthyma gangraenosum due to central venous catheter-related bloodstream infection with Pseudomonas aeruginosa. ( 30187217 )
2018
11
Ecthyma Gangrenosum in Paroxysmal Nocturnal Hemoglobinuria. ( 30300881 )
2018
12
First report of camel contagious ecthyma in Nigeria. ( 30425954 )
2018
13
Clinical Manifestation, Dermoscopy, and Scanning Electron Microscopy in Two Cases of Contagious Ecthyma (Orf Nodule). ( 30510811 )
2018
14
Septic shock related to community-acquired pneumonia with ecthyma gangrenosum. ( 30528272 )
2018
15
Successful Use of Negative-pressure Wound Therapy and Dermal Substitute in the Treatment of Gluteal Ecthyma Gangrenosum in a 2-year-old Girl. ( 30534498 )
2018
16
Ecthyma gangrenosum caused by Klebsiella pneumoniae and Streptococcus vestibularis in a patient with acute myeloid leukemia: an emerging pathogen. ( 30548464 )
2018
17
Ecthyma gangrenosum, a skin manifestation of Pseudomonas aeruginosa sepsis in a previously healthy child: A case report. ( 28079790 )
2017
18
Pasteurella multocida ecthyma complicated by necrotizing fasciitis. ( 28541874 )
2017
19
Ecthyma gangrenosum: a report of eight cases. ( 29166510 )
2017
20
Ecthyma Gangrenosum in the Eyelid. ( 29084109 )
2017
21
Ecthyma gangrenosum caused by Citrobacter freundii. ( 28751433 )
2017
22
Ecthyma Gangrenosum: Escherichia coli or Pseudomonas aeruginosa? ( 28611752 )
2017
23
Ecthyma Gangrenosum. ( 29211664 )
2017
24
Ecthyma gangrenosum in a 3-month-old, previously healthy infant: A Case Report. ( 28272221 )
2017
25
Non-pseudomonal ecthyma gangrenosum caused by methicillin-resistant Staphylococcus aureus (MRSA) in a chronic alcoholic patient. ( 28775089 )
2017
26
Ecthyma gangrenosum as first manifestation of acute leukemia. ( 28736062 )
2017
27
Ecthyma gangrenosum in a case of acute lymphoblastic lymphoma. ( 28052953 )
2017
28
Identification and phylogenetic analysis of contagious ecthyma virus from camels (<i>Camelus dromedarius</i>) in Iran. ( 28397518 )
2017
29
Wife to husband transmission of Ecthyma contagiosum (Orf). ( 28560176 )
2017
30
Ecthyma gangrenosum without bacteraemia: evidence in favour of a broader definition. ( 28239902 )
2017
31
Ecthyma associated with Moraxella and Staphylococcus epidermidis. ( 27981222 )
2016
32
Orf virus infection in human ecthyma contagiosum: a report of two cases in the West of Iran. ( 27366776 )
2016
33
Ecthyma gangrenosum in the periorbital region in a previously healthy immunocompetent woman without bacteremia. ( 26955586 )
2016
34
Disseminated Candida tropicalis presenting with Ecthyma-Gangrenosum-like Lesions. ( 26990472 )
2016
35
Ecthyma gangrenosum of the scrotum: a case report. ( 26941196 )
2016
36
Case of ecthyma gangrenosum in which only methicillin-resistant Staphylococcus epidermidis was detected. ( 26703091 )
2016
37
Ecthyma gangrenosum in a renal transplant recipient. ( 27493006 )
2016
38
Dermoscopy of contagious ecthyma (orf nodule). ( 27085247 )
2016
39
Ecthyma gangrenosum in an infant after liver transplantation. ( 27682614 )
2016
40
Seroprevalence of contagious ecthyma in goats of Assam: An analysis by indirect enzyme-linked immunosorbent assay. ( 27733808 )
2016
41
Tularemia Masquerading as Ecthyma. ( 27562918 )
2016
42
An Extraordinary Cause of the Sucking Difficulty: Ecthyma Gangrenosum. ( 27143976 )
2016
43
A case of perineal ecthyma gangrenosum. ( 27103864 )
2016
44
Ecthyma gangrenosum secondary to methicillin-sensitive Staphylococcus aureus. ( 28492017 )
2016
45
The Concept of Ecthyma Gangrenosum Illustrated by a Fusarium oxysporum Infection in an Immunocompetent Individual. ( 27324372 )
2016
46
Atypical case of ecthyma gangrenosum mimicking a breast cancer recurrence. ( 27030458 )
2016
47
Ecthyma gangrenosum-like lesions in a case of disseminated Mycobacterium tuberculosis in a renal transplant recipient. ( 27727755 )
2016
48
Occurrence and identification of contagious ecthyma in blackbuck. ( 27366773 )
2016
49
Contagious Ecthyma, Rangiferine Brucellosis, and Lungworm Infection in a Muskox ( Ovibos moschatus ) from the Canadian Arctic, 2014. ( 27285415 )
2016
50
Nonpseudomonal ecthyma gangrenosum of the upper lid treated with lid reconstruction. ( 26655009 )
2015

Variations for Ecthyma

Expression for Ecthyma

Search GEO for disease gene expression data for Ecthyma.

Pathways for Ecthyma

Pathways related to Ecthyma according to GeneCards Suite gene sharing:

(show all 18)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.57 ALK BTK CD4 COL17A1 CSF2 CSF3
2
Show member pathways
13.12 BTK CD4 CSF2 CSF3 FGF2 TNFRSF8
3
Show member pathways
13.11 CD4 CSF2 CSF3 FGF2 GATA3 STAT6
4
Show member pathways
13.07 ALK BTK CD4 CSF2 CSF3 FGF2
5
Show member pathways
12.4 CD4 GATA3 STAT6 TBX21
6 12.17 BTK GATA3 STAT6 TBX21 TNFRSF8
7
Show member pathways
11.86 CD4 GATA3 TBX21
8 11.78 FGF2 GATA3 STAT6
9
Show member pathways
11.77 CD4 STAT6 TBX21
10 11.69 CD4 CSF2 CSF3
11 11.6 CSF2 GATA3 TBX21
12 11.57 CD4 GATA3 TBX21
13
Show member pathways
11.53 CSF2 GATA3 TBX21
14 11.52 CD4 CD79B CSF2 CSF3
15 11.41 CSF2 CSF3 FGF2
16 11.21 CD4 GATA3 STAT6
17 10.59 CD4 CSF2 CSF3
18 10.07 ALK BTK COL17A1 CSF2 CSF3 FGF2

GO Terms for Ecthyma

Cellular components related to Ecthyma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 basement membrane GO:0005604 9.13 COL17A1 DST LAMB2
2 hemidesmosome GO:0030056 8.62 COL17A1 DST

Biological processes related to Ecthyma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 T cell receptor signaling pathway GO:0050852 9.61 BTK CD4 GATA3
2 peptidyl-tyrosine phosphorylation GO:0018108 9.56 ALK BTK CSF2 FGF2
3 negative regulation of interleukin-2 production GO:0032703 9.4 GATA3 TBX21
4 hemidesmosome assembly GO:0031581 9.37 COL17A1 DST
5 cellular response to granulocyte macrophage colony-stimulating factor stimulus GO:0097011 9.32 CD4 CSF2
6 lymphocyte migration GO:0072676 9.16 GATA3 TBX21
7 T cell differentiation GO:0030217 9.13 CD4 GATA3 TBX21
8 cytokine-mediated signaling pathway GO:0019221 9.1 CD4 CSF2 CSF3 FGF2 GATA3 STAT6

Molecular functions related to Ecthyma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 integrin binding GO:0005178 9.43 DST FGF2 LAMB2
2 extracellular matrix structural constituent GO:0005201 9.33 CD4 COL17A1 LAMB2
3 transmembrane signaling receptor activity GO:0004888 9.26 ALK CD4 CD79B TNFRSF8
4 protein tyrosine kinase activity GO:0004713 8.92 ALK BTK CSF2 FGF2

Sources for Ecthyma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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