MCID: ECT003
MIFTS: 26

Ectopic Thymus

Categories: Immune diseases

Aliases & Classifications for Ectopic Thymus

MalaCards integrated aliases for Ectopic Thymus:

Name: Ectopic Thymus 12 15 70

Classifications:



External Ids:

Disease Ontology 12 DOID:6307
NCIt 50 C27804
UMLS 70 C1333375

Summaries for Ectopic Thymus

MalaCards based summary : Ectopic Thymus is related to thymic carcinoma and goiter. An important gene associated with Ectopic Thymus is ICOSLG (Inducible T Cell Costimulator Ligand). Affiliated tissues include thymus, thyroid and bone marrow.

Wikipedia : 73 Ectopic thymus is a condition where thymus tissue is found in an abnormal location. It is thought to be... more...

Related Diseases for Ectopic Thymus

Diseases related to Ectopic Thymus via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 97)
# Related Disease Score Top Affiliating Genes
1 thymic carcinoma 29.4 TG NKX2-1 CD5
2 goiter 29.4 TG NKX2-1 CALCA
3 thyroid carcinoma 29.4 TG NKX2-1 CALCA
4 papillary carcinoma 29.3 TG NKX2-1 CALCA
5 type c thymoma 10.2 FOXN1 CD5
6 t cell deficiency 10.2 ICOSLG FOXN1
7 anemia, autoimmune hemolytic 10.1 ICOSLG CD5
8 autoimmune disease of blood 10.1 ICOSLG CD5
9 thyrotoxic exophthalmos 10.1 TG CD5
10 endocrine exophthalmos 10.1 TG CD5
11 papillary thymic adenocarcinoma 10.1 TG CD5
12 dendritic cell thymoma 10.1 TG CD5
13 thyroid gland mucoepidermoid carcinoma 10.1 TG CALCA
14 nodular goiter 10.1 TG CALCA
15 isthmus cancer 10.1 TG CALCA
16 breast osteosarcoma 10.1 KRT8 CD5
17 atypical follicular adenoma 10.1 TG CALCA
18 lymphangioma 10.1
19 rare lymphatic malformation 10.1
20 thyroid sarcoma 10.1 TG CALCA
21 thymus basaloid carcinoma 10.1 NKX2-1 CD5
22 nonencapsulated sclerosing carcinoma 10.1 TG CALCA
23 acute thyroiditis 10.1 TG CALCA
24 fetal adenoma 10.1 TG CALCA
25 ureteral benign neoplasm 10.1 NKX2-1 GCM2
26 thymus gland disease 10.1 ICOSLG CD5
27 orbital disease 10.1 TG CD5
28 hypothyroidism, thyroidal or athyroidal, with spiky hair and cleft palate 10.0 NKX2-1 FOXN1
29 endemic goiter 10.0 TG CALCA
30 thymus clear cell carcinoma 10.0 NKX2-1 CD5
31 suppurative thyroiditis 10.0 TG CALCA
32 familial hypocalciuric hypercalcemia 10.0 GCM2 CALCA
33 mediastinal cancer 10.0 NKX2-1 CD5
34 graves disease 1 10.0 TG CALCA
35 thymoma, familial 10.0
36 lymphoblastic lymphoma 10.0
37 hemangioma 10.0
38 thymoma 10.0
39 precursor t-cell acute lymphoblastic leukemia 10.0
40 malignant struma ovarii 10.0 TG NKX2-1
41 struma ovarii 10.0 TG NKX2-1
42 athyreosis 10.0 TG NKX2-1
43 tall cell variant papillary carcinoma 10.0 TG NKX2-1
44 sclerosing hemangioma 10.0 NKX2-1 CALCA
45 ovarian germ cell teratoma 10.0 TG NKX2-1
46 sarcomatous intrahepatic cholangiocarcinoma 10.0 NKX2-1 KRT8
47 autoimmune disease of endocrine system 10.0 TG ICOSLG
48 mammary paget's disease 10.0 KRT8 CALCA
49 cutaneous adenocystic carcinoma 10.0 NKX2-1 KRT8
50 hypersensitivity reaction type iv disease 9.9 ICOSLG CD5

Graphical network of the top 20 diseases related to Ectopic Thymus:



Diseases related to Ectopic Thymus

Symptoms & Phenotypes for Ectopic Thymus

Drugs & Therapeutics for Ectopic Thymus

Search Clinical Trials , NIH Clinical Center for Ectopic Thymus

Genetic Tests for Ectopic Thymus

Anatomical Context for Ectopic Thymus

MalaCards organs/tissues related to Ectopic Thymus:

40
Thymus, Thyroid, Bone Marrow, Lymph Node, Breast, Uterus, Skin

Publications for Ectopic Thymus

Articles related to Ectopic Thymus:

(show top 50) (show all 147)
# Title Authors PMID Year
1
Intrathyroidal Ectopic Thymus and Sonoelastographic Findings. 61
33781193 2021
2
Ultrasound Imaging of Cervical Anatomic Variants. 61
33504311 2021
3
Interobserver Agreement and Plane-Dependent Intraobserver Variability of Shear Wave Sonoelastography in the Differential Diagnosis of Ectopic Thymus Tissue. 61
33435276 2021
4
Intermittent Suprasternal Neck Mass Caused by Herniation of Ectopic Thymus: Report of Two Cases. 61
33282788 2020
5
Application of Shear Wave Sonoelastography in the Differential Diagnosis of Extra- and Intra-Thyroidal Ectopic Thymic Tissue. 61
33255780 2020
6
Ectopic Cervical Thymus: A Common, yet Rarely Symptomatic Pediatric Neck Mass 61
33115395 2020
7
Ectopic cervical thymus in children: Clinical and radiographic features. 61
31461169 2020
8
Long-term ultrasound follow-up of intrathyroidal ectopic thymus in children. 61
31902058 2020
9
Pharyngeal Ectopic Thymus: A Case Report. 61
32320300 2020
10
Intrathyroidal ectopic thymus in 8-year-old girl: a case report. 61
32154138 2020
11
Ectopic thymus as a cause of Horner's syndrome. 61
31737141 2020
12
Clinical Characteristics of and Cancer Incidence in Children Evaluated for Lymphadenoapthy Referred to Pediatric Oncology Clinics. 61
32617063 2020
13
Ectopic Thymus: An Unusual Case of Subglottic Mass. 61
31319699 2019
14
Intrathyroidal ectopic thymus tissue: emphasis on details. 61
31286340 2019
15
Challenges in diagnosing ectopic thymus tissue in children. 61
31533948 2019
16
Intrathyroidal ectopic thymus tissue: a diagnostic challenge. 61
30710204 2019
17
Diagnosis of intrathyroidal ectopic thymus in thyroid fine needle aspiration samples. 61
30385479 2019
18
Sonographic and Elastographic Features of Extra- and Intrathyroidal Ectopic Thymus Mimicking Malignancy: Differential Diagnosis in Children. 61
31110490 2019
19
Utility of monoclonal PAX8 antibody for distinguishing intrathyroid thymic carcinoma from follicular cell-derived thyroid carcinoma. 61
30210064 2018
20
Difficult intubation in a neonate: a diagnostic dilemma. 61
30567083 2018
21
Intrathyroid cystic thyroglossal duct remnant and ectopic thymus: a fortuitous or development-related association? 61
29460127 2018
22
Prevalence and sonographic features of ectopic thyroidal thymus in children: A retrospective analysis. 61
29575022 2018
23
Cytomorphology and sonographic features of ectopic thymic tissue diagnosed in paediatric FNA biopsies. 61
29577488 2018
24
Intrathyroidal ectopic thymus in children: A benign lesion. 61
29620644 2018
25
[Ectopic thymus: A rare cause of neck mass in children]. 61
28689684 2017
26
Intrathyroidal ectopic thymus in children: a sonographic survey. 61
28440352 2017
27
Ectopic intrathyroidal thymus in children: Prevalence, imaging findings and evolution. 61
29624218 2017
28
Diagnostic imaging of benign and malignant neck masses in children-a pictorial review. 61
27942480 2016
29
Myasthenia gravis in patients with thymoma affects survival rate following extended thymectomy. 61
27313762 2016
30
Preoperative Anxiety in Patients With Myasthenia Gravis and Risk for Myasthenic Crisis After Extended Transsternal Thymectomy: A CONSORT Study. 61
26962777 2016
31
Intrathyroidal Ectopic Thymus in Children: Retrospective Analysis of Grayscale and Doppler Sonographic Features. 61
26269296 2015
32
[A Case of Infantile Cervical Ectopic Thymus]. 61
26349279 2015
33
Distribution of mediastinal ectopic thymic tissue in patients without thymic disease. 61
25709983 2015
34
Hi-TEC reprogramming for organ regeneration. 61
25174818 2014
35
Intrathyroidal thymic tissue mimicking a malignant thyroid nodule in a 4-year-old child. 61
24936498 2014
36
Retropharyngeal thymus and parathyroid gland: a case report. 61
24309004 2014
37
Changes in pediatric thyroid sonograms in or nearby the Kanto region before and after the accident at the Fukushima Daiichi nuclear power plant. 61
25008050 2014
38
Branchio-oculo-facial syndrome in a newborn caused by a novel TFAP2A mutation. 61
24783654 2014
39
Carcinoma showing thymus-like differentiation of the thyroid (CASTLE). 61
23920320 2013
40
[Cervical ectopic thymus: a rare condition]. 61
23481465 2013
41
Intrathyroidal epithelial thymoma/carcinoma showing thymus-like differentiation; comparison with thymic lymphoepithelioma-like carcinoma and a possibility of development from a multipotential stem cell. 61
23176314 2013
42
Outcomes after thymectomy in class I myasthenia gravis. 61
23312978 2013
43
Original report of bilateral carotid body tumors with 2 rare concomitant anatomic findings, an ectopic parathyroid gland and cervical thymus, with literature review. 61
22076658 2013
44
A rare case of ectopic laterocervical thymoma. 61
22687955 2013
45
Thyroid ultrasound findings in children from three Japanese prefectures: Aomori, Yamanashi and Nagasaki. 61
24376666 2013
46
Ectopic thymus presenting as a retropharyngeal mass: surgical approach. 61
23354892 2013
47
Infant ectopic cervical thymus one case report: diagnostic and management difficulties. 61
22266225 2012
48
Branchiooculofacial syndrome and bilateral ectopic thymus: report of a family. 61
23106675 2012
49
Thrombosed cavernous hemangioma arising in cervical ectopic thymus tissue: a case report. 61
23248863 2012
50
Solid ectopic cervical thymus in neonates with thyroid agenesis. 61
22837294 2012

Variations for Ectopic Thymus

Expression for Ectopic Thymus

Search GEO for disease gene expression data for Ectopic Thymus.

Pathways for Ectopic Thymus

GO Terms for Ectopic Thymus

Cellular components related to Ectopic Thymus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chromatin GO:0000785 9.02 TFAP2A NKX2-1 HOXA3 GCM2 FOXN1

Biological processes related to Ectopic Thymus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of transcription, DNA-templated GO:0006355 9.72 TFAP2A NKX2-1 HOXA3 GCM2 FOXN1
2 T cell costimulation GO:0031295 9.37 ICOSLG CD5
3 animal organ morphogenesis GO:0009887 9.33 NKX2-1 HOXA3 FOXN1
4 thymus development GO:0048538 9.26 HOXA3 FOXN1
5 parathyroid gland development GO:0060017 8.96 HOXA3 GCM2
6 thyroid gland development GO:0030878 8.8 TG NKX2-1 HOXA3

Molecular functions related to Ectopic Thymus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 DNA-binding transcription factor activity GO:0003700 9.56 TFAP2A NKX2-1 HOXA3 FOXN1
2 DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 9.35 TFAP2A NKX2-1 HOXA3 GCM2 FOXN1
3 transcription regulatory region sequence-specific DNA binding GO:0000976 9.33 TFAP2A NKX2-1 FOXN1
4 sequence-specific DNA binding GO:0043565 8.92 TFAP2A NKX2-1 GCM2 FOXN1

Sources for Ectopic Thymus

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
Content
Loading form....