MCID: ECT003
MIFTS: 27

Ectopic Thymus

Categories: Endocrine diseases, Immune diseases

Aliases & Classifications for Ectopic Thymus

MalaCards integrated aliases for Ectopic Thymus:

Name: Ectopic Thymus 12 15 74

Classifications:



External Ids:

Disease Ontology 12 DOID:6307
NCIt 51 C27804
UMLS 74 C1333375

Summaries for Ectopic Thymus

MalaCards based summary : Ectopic Thymus is related to mixed type thymoma and mediastinal cancer. An important gene associated with Ectopic Thymus is TFAP2A (Transcription Factor AP-2 Alpha), and among its related pathways/superpathways is Corticotropin-releasing hormone signaling pathway. Affiliated tissues include thymus, b cells and thyroid, and related phenotypes are integument and normal

Wikipedia : 77 Ectopic thymus is a condition where thymus tissue is found in an abnormal... more...

Related Diseases for Ectopic Thymus

Graphical network of the top 20 diseases related to Ectopic Thymus:



Diseases related to Ectopic Thymus

Symptoms & Phenotypes for Ectopic Thymus

MGI Mouse Phenotypes related to Ectopic Thymus:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 9.46 BCL2 CD5 FOXN1 TFAP2A
2 normal MP:0002873 9.35 CD5 FOXN1 OMG SYP TFAP2A
3 pigmentation MP:0001186 8.8 BCL2 FOXN1 TFAP2A

Drugs & Therapeutics for Ectopic Thymus

Search Clinical Trials , NIH Clinical Center for Ectopic Thymus

Genetic Tests for Ectopic Thymus

Anatomical Context for Ectopic Thymus

MalaCards organs/tissues related to Ectopic Thymus:

42
Thymus, B Cells, Thyroid

Publications for Ectopic Thymus

Articles related to Ectopic Thymus:

(show all 42)
# Title Authors Year
1
Diagnosis of intrathyroidal ectopic thymus in thyroid fine needle aspiration samples. ( 30385479 )
2019
2
Intrathyroidal ectopic thymus tissue: a diagnostic challenge. ( 30710204 )
2019
3
Sonographic and Elastographic Features of Extra- and Intrathyroidal Ectopic Thymus Mimicking Malignancy: Differential Diagnosis in Children. ( 31110490 )
2019
4
Intrathyroid cystic thyroglossal duct remnant and ectopic thymus: a fortuitous or development-related association? ( 29460127 )
2018
5
Intrathyroidal ectopic thymus in children: A benign lesion. ( 29620644 )
2018
6
Intrathyroidal ectopic thymus in children: a sonographic survey. ( 28440352 )
2017
7
Intrathyroidal Ectopic Thymus in Children: Retrospective Analysis of Grayscale and Doppler Sonographic Features. ( 26269296 )
2015
8
Ectopic thymus presenting as a retropharyngeal mass: surgical approach. ( 23354892 )
2013
9
Branchiooculofacial syndrome and bilateral ectopic thymus: report of a family. ( 23106675 )
2012
10
Thrombosed cavernous hemangioma arising in cervical ectopic thymus tissue: a case report. ( 23248863 )
2012
11
Active ectopic thymus predicts poor outcome after thymectomy in class III myasthenia gravis. ( 22177829 )
2012
12
Sonographic appearance of intrathyroid ectopic thymus in children. ( 22362225 )
2012
13
Radiology quiz case 2. Ectopic thymus. ( 21339410 )
2011
14
Ectopic thymus presenting as neck mass in a neonate: a case report. ( 21654604 )
2011
15
Clinical management of cervical ectopic thymus in children. ( 21843706 )
2011
16
Vascularized tissue engineering mouse chamber model supports thymopoiesis of ectopic thymus tissue grafts. ( 19715386 )
2010
17
Cervical ectopic thymus masquerading as metastatic thyroid papillary carcinoma. ( 20614729 )
2010
18
Inspiratory stridor and dysphagia in two newborn infants caused by ectopic thymus tissue. ( 19104836 )
2009
19
Ectopic thymus presenting as a right-side cervical mass in an infant. ( 18839165 )
2009
20
Cervical ectopic thymus. ( 19177048 )
2009
21
Ectopic thymus presenting as a thyroid nodule in a patient with the Carney complex. ( 19265501 )
2009
22
Clear cell carcinoma originating from ectopic thymus. ( 19440827 )
2009
23
Solid cervical ectopic thymus in an infant. ( 19573646 )
2009
24
Cervical ectopic thymus in a 9-month-old girl: diagnostic difficulties. ( 19641469 )
2009
25
Case of right-neck tumor that appears to be ectopic thymus. ( 27277227 )
2009
26
Cervical ectopic thymus presenting as a painless neck mass in a child. ( 17966246 )
2007
27
Cervical ectopic thymus in an infant. ( 16397725 )
2006
28
Images in pathology: micronodular epithelial hyperplasia in ectopic thymus. ( 16501838 )
2006
29
Ectopic thymus presenting as a subglottic mass: diagnostic and management dilemmas. ( 15763300 )
2005
30
Cervical ectopic thymus: a case report and review of the literature. ( 12363426 )
2002
31
The analogy in cell immunophenotype and parameters of cell cycle of ectopic thymus, normal thymus, and some acute lymphoblastic leukemia of T-phenotype. ( 12458329 )
2002
32
Ectopic thymus presenting as neck mass. ( 12508495 )
2002
33
Adult ectopic thymus adjacent to thyroid and parathyroid. ( 11371249 )
2001
34
Ectopic thymus presenting as a submandibular swelling. ( 11474464 )
2001
35
Ectopic thymus presenting as a solid submandibular neck mass in an infant: case report and review of literature. ( 10519705 )
1999
36
Ectopic thymus presenting as a neck swelling in a newborn. ( 17341962 )
1998
37
Malignant thymoma in an ectopic thymus: CT appearance. ( 1885808 )
1991
38
Bilateral ectopic thymus gland tissue associated with the cleft lip and palate. ( 2748765 )
1989
39
Ectopic thymus in the neck; a case report and review of the literature. ( 3676587 )
1987
40
Ectopic thymus: presenting as neck mass. ( 6726580 )
1984
41
Radiologic seminar CCVII: ectopic thymus. ( 7431388 )
1980
42
Ectopic thymus of the neck--report of three examples in children. ( 1161677 )
1975

Variations for Ectopic Thymus

Expression for Ectopic Thymus

Search GEO for disease gene expression data for Ectopic Thymus.

Pathways for Ectopic Thymus

Pathways related to Ectopic Thymus according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.59 BCL2 TFAP2A

GO Terms for Ectopic Thymus

Biological processes related to Ectopic Thymus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell proliferation GO:0008283 9.58 BCL2 CD5 FOXN1
2 animal organ morphogenesis GO:0009887 9.48 BCL2 FOXN1
3 kidney development GO:0001822 9.46 BCL2 TFAP2A
4 hemopoiesis GO:0030097 9.43 BCL2 FOXN1
5 thymus development GO:0048538 9.37 BCL2 FOXN1
6 cellular response to organic substance GO:0071310 9.32 BCL2 SYP
7 T cell homeostasis GO:0043029 9.26 BCL2 FOXN1
8 negative regulation of reactive oxygen species metabolic process GO:2000378 9.16 BCL2 TFAP2A
9 lymphocyte homeostasis GO:0002260 8.96 BCL2 FOXN1
10 T cell lineage commitment GO:0002360 8.62 BCL2 FOXN1

Molecular functions related to Ectopic Thymus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sequence-specific DNA binding GO:0043565 8.8 BCL2 FOXN1 TFAP2A

Sources for Ectopic Thymus

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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