MCID: ECT003
MIFTS: 25

Ectopic Thymus

Categories: Immune diseases

Aliases & Classifications for Ectopic Thymus

MalaCards integrated aliases for Ectopic Thymus:

Name: Ectopic Thymus 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:6307
NCIt 49 C27804
UMLS 71 C1333375

Summaries for Ectopic Thymus

MalaCards based summary : Ectopic Thymus is related to thymoma and goiter. An important gene associated with Ectopic Thymus is ICOSLG (Inducible T Cell Costimulator Ligand). Affiliated tissues include thymus, thyroid and bone marrow.

Wikipedia : 74 Ectopic thymus is a condition where thymus tissue is found in an abnormal location. It is thought to be... more...

Related Diseases for Ectopic Thymus

Diseases related to Ectopic Thymus via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 93)
# Related Disease Score Top Affiliating Genes
1 thymoma 29.7 TG NKX2-1 CD5
2 goiter 29.4 TG NKX2-1 CALCA
3 thyroid carcinoma 29.4 TG NKX2-1 CALCA
4 thyroiditis 29.4 TG NKX2-1 CALCA
5 papillary carcinoma 29.3 TG NKX2-1 CALCA
6 thymic carcinoma 29.0 TG NKX2-1 CD5 CALCA
7 type c thymoma 10.3 FOXN1 CD5
8 t cell deficiency 10.2 ICOSLG FOXN1
9 thyroid gland mucoepidermoid carcinoma 10.2 TG CALCA
10 thyrotoxic exophthalmos 10.2 TG CD5
11 nodular goiter 10.2 TG CALCA
12 anemia, autoimmune hemolytic 10.2 ICOSLG CD5
13 papillary thymic adenocarcinoma 10.2 TG CD5
14 atypical follicular adenoma 10.2 TG CALCA
15 endocrine exophthalmos 10.2 TG CD5
16 substernal goiter 10.1 TG CALCA
17 thyroid sarcoma 10.1 TG CALCA
18 isthmus cancer 10.1 TG CALCA
19 thymus basaloid carcinoma 10.1 NKX2-1 CD5
20 fetal adenoma 10.1 TG CALCA
21 nonencapsulated sclerosing carcinoma 10.1 TG CALCA
22 multiple endocrine neoplasia 10.1 CNC2 CALCA
23 acute thyroiditis 10.1 TG CALCA
24 orbital disease 10.1 TG TFAP2A
25 hypothyroidism, thyroidal or athyroidal, with spiky hair and cleft palate 10.1 NKX2-1 FOXN1
26 autoimmune disease of blood 10.1 ICOSLG CD5
27 ureter small cell carcinoma 10.1 NKX2-1 CALCA
28 endemic goiter 10.1 TG CALCA
29 thymus clear cell carcinoma 10.1 NKX2-1 CD5
30 malignant struma ovarii 10.1 TG NKX2-1
31 struma ovarii 10.1 TG NKX2-1
32 mediastinal cancer 10.1 NKX2-1 CD5
33 lymphangioma 10.1
34 rare lymphatic malformation 10.1
35 graves disease 1 10.0 TG CALCA
36 colon neuroendocrine neoplasm 10.0 NKX2-1 CALCA
37 athyreosis 10.0 TG NKX2-1
38 tall cell variant papillary carcinoma 10.0 TG NKX2-1
39 ovarian germ cell teratoma 10.0 TG NKX2-1
40 sclerosing hemangioma 10.0 NKX2-1 CALCA
41 ovarian germ cell cancer 10.0 TG NKX2-1
42 nontoxic goiter 10.0 TG ICOSLG CALCA
43 thymoma, familial 10.0
44 lymphoblastic lymphoma 10.0
45 hemangioma 10.0
46 precursor t-cell acute lymphoblastic leukemia 10.0
47 autoimmune disease of endocrine system 10.0 TG ICOSLG CALCA
48 thyroid gland medullary carcinoma 10.0 TG CALCA
49 hypothyroidism, congenital, nongoitrous, 2 10.0 TG NKX2-1
50 thymus cancer 9.9 NKX2-1 ICOSLG CD5

Graphical network of the top 20 diseases related to Ectopic Thymus:



Diseases related to Ectopic Thymus

Symptoms & Phenotypes for Ectopic Thymus

Drugs & Therapeutics for Ectopic Thymus

Search Clinical Trials , NIH Clinical Center for Ectopic Thymus

Genetic Tests for Ectopic Thymus

Anatomical Context for Ectopic Thymus

MalaCards organs/tissues related to Ectopic Thymus:

40
Thymus, Thyroid, Bone Marrow, Bone, Lymph Node, Skin, Testes

Publications for Ectopic Thymus

Articles related to Ectopic Thymus:

(show top 50) (show all 140)
# Title Authors PMID Year
1
Long-term ultrasound follow-up of intrathyroidal ectopic thymus in children. 61
31902058 2020
2
Ectopic cervical thymus in children: Clinical and radiographic features. 61
31461169 2020
3
Pharyngeal Ectopic Thymus: A Case Report. 61
32320300 2020
4
Intrathyroidal ectopic thymus in 8-year-old girl: a case report. 61
32154138 2020
5
Ectopic thymus as a cause of Horner's syndrome. 61
31737141 2020
6
Ectopic Thymus: An Unusual Case of Subglottic Mass. 61
31319699 2019
7
Intrathyroidal ectopic thymus tissue: emphasis on details. 61
31286340 2019
8
Challenges in diagnosing ectopic thymus tissue in children. 61
31533948 2019
9
Intrathyroidal ectopic thymus tissue: a diagnostic challenge. 61
30710204 2019
10
Diagnosis of intrathyroidal ectopic thymus in thyroid fine needle aspiration samples. 61
30385479 2019
11
Sonographic and Elastographic Features of Extra- and Intrathyroidal Ectopic Thymus Mimicking Malignancy: Differential Diagnosis in Children. 61
31110490 2019
12
Utility of monoclonal PAX8 antibody for distinguishing intrathyroid thymic carcinoma from follicular cell-derived thyroid carcinoma. 61
30210064 2018
13
Difficult intubation in a neonate: a diagnostic dilemma. 61
30567083 2018
14
Intrathyroid cystic thyroglossal duct remnant and ectopic thymus: a fortuitous or development-related association? 61
29460127 2018
15
Prevalence and sonographic features of ectopic thyroidal thymus in children: A retrospective analysis. 61
29575022 2018
16
Cytomorphology and sonographic features of ectopic thymic tissue diagnosed in paediatric FNA biopsies. 61
29577488 2018
17
Intrathyroidal ectopic thymus in children: A benign lesion. 61
29620644 2018
18
[Ectopic thymus: A rare cause of neck mass in children]. 61
28689684 2017
19
Intrathyroidal ectopic thymus in children: a sonographic survey. 61
28440352 2017
20
Ectopic intrathyroidal thymus in children: Prevalence, imaging findings and evolution. 61
29624218 2017
21
Diagnostic imaging of benign and malignant neck masses in children-a pictorial review. 61
27942480 2016
22
Myasthenia gravis in patients with thymoma affects survival rate following extended thymectomy. 61
27313762 2016
23
Preoperative Anxiety in Patients With Myasthenia Gravis and Risk for Myasthenic Crisis After Extended Transsternal Thymectomy: A CONSORT Study. 61
26962777 2016
24
Intrathyroidal Ectopic Thymus in Children: Retrospective Analysis of Grayscale and Doppler Sonographic Features. 61
26269296 2015
25
[A Case of Infantile Cervical Ectopic Thymus]. 61
26349279 2015
26
Distribution of mediastinal ectopic thymic tissue in patients without thymic disease. 61
25709983 2015
27
Hi-TEC reprogramming for organ regeneration. 61
25174818 2014
28
Retropharyngeal thymus and parathyroid gland: a case report. 61
24309004 2014
29
Intrathyroidal thymic tissue mimicking a malignant thyroid nodule in a 4-year-old child. 61
24936498 2014
30
Branchio-oculo-facial syndrome in a newborn caused by a novel TFAP2A mutation. 61
24783654 2014
31
Changes in pediatric thyroid sonograms in or nearby the Kanto region before and after the accident at the Fukushima Daiichi nuclear power plant. 61
25008050 2014
32
Carcinoma showing thymus-like differentiation of the thyroid (CASTLE). 61
23920320 2013
33
[Cervical ectopic thymus: a rare condition]. 61
23481465 2013
34
Intrathyroidal epithelial thymoma/carcinoma showing thymus-like differentiation; comparison with thymic lymphoepithelioma-like carcinoma and a possibility of development from a multipotential stem cell. 61
23176314 2013
35
Outcomes after thymectomy in class I myasthenia gravis. 61
23312978 2013
36
Original report of bilateral carotid body tumors with 2 rare concomitant anatomic findings, an ectopic parathyroid gland and cervical thymus, with literature review. 61
22076658 2013
37
Thyroid ultrasound findings in children from three Japanese prefectures: Aomori, Yamanashi and Nagasaki. 61
24376666 2013
38
A rare case of ectopic laterocervical thymoma. 61
22687955 2013
39
Ectopic thymus presenting as a retropharyngeal mass: surgical approach. 61
23354892 2013
40
Infant ectopic cervical thymus one case report: diagnostic and management difficulties. 61
22266225 2012
41
Branchiooculofacial syndrome and bilateral ectopic thymus: report of a family. 61
23106675 2012
42
Solid ectopic cervical thymus in neonates with thyroid agenesis. 61
22837294 2012
43
Thrombosed cavernous hemangioma arising in cervical ectopic thymus tissue: a case report. 61
23248863 2012
44
Sonographic appearance of intrathyroid ectopic thymus in children. 61
22362225 2012
45
Active ectopic thymus predicts poor outcome after thymectomy in class III myasthenia gravis. 61
22177829 2012
46
[Right submandibular ectopic thymus: a case report]. 61
22389979 2012
47
Ectopic cervical thymoma: a case report with 18F-fluorodeoxyglucose positron emission tomography findings. 61
22918209 2012
48
Posterior mediastinal thymus: case report and literature review. 61
23056822 2011
49
[Cervical ectopic thymus in an infant]. 61
21932674 2011
50
Clinical management of cervical ectopic thymus in children. 61
21843706 2011

Variations for Ectopic Thymus

Expression for Ectopic Thymus

Search GEO for disease gene expression data for Ectopic Thymus.

Pathways for Ectopic Thymus

GO Terms for Ectopic Thymus

Cellular components related to Ectopic Thymus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nuclear chromatin GO:0000790 9.02 TFAP2A NKX2-1 HOXA3 GCM2 FOXN1

Biological processes related to Ectopic Thymus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription by RNA polymerase II GO:0045944 9.72 TFAP2A NKX2-1 HOXA3 GCM2 FOXN1
2 regulation of transcription, DNA-templated GO:0006355 9.63 ZNF117 TFAP2A NKX2-1 HOXA3 GCM2 FOXN1
3 animal organ morphogenesis GO:0009887 9.43 NKX2-1 HOXA3 FOXN1
4 thymus development GO:0048538 9.37 HOXA3 FOXN1
5 parathyroid gland development GO:0060017 8.96 HOXA3 GCM2
6 thyroid gland development GO:0030878 8.8 TG NKX2-1 HOXA3

Molecular functions related to Ectopic Thymus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978 9.56 ZNF117 TFAP2A NKX2-1 HOXA3
2 DNA-binding transcription factor activity GO:0003700 9.55 ZNF117 TFAP2A NKX2-1 HOXA3 FOXN1
3 DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 9.35 TFAP2A NKX2-1 HOXA3 GCM2 FOXN1
4 sequence-specific DNA binding GO:0043565 9.02 TFAP2A NKX2-1 HOXA3 GCM2 FOXN1

Sources for Ectopic Thymus

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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