Home
User Guide
What's in a MalaCard Search Guide Our Sources
Analysis Tools
GeneCards GeneAnalytics GeneAlaCart PathCards VarElect TGex
News and Views Disease Lists/Categories
About
About MalaCards Datasets Our Publications Weizmann Institute LifeMap Discovery® Terms of Use MalaCards Team
MCID: EGG001
MIFTS: 44

Egg Allergy

Categories: Immune diseases
Genes Tissues Related diseases Publications Pathways Drugs
Sources

Aliases & Classifications for Egg Allergy

About this section

MalaCards integrated aliases for Egg Allergy:

Name: Egg Allergy 12 15 17
Egg Hypersensitivity 43
Allergy to Eggs 12
Allergies Egg 54

Classifications:

MalaCards categories:
Anatomical: Immune diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:4377
MeSH 43 D021181
SNOMED-CT 67 91930004
UMLS 71 C0559469
Sources

Summaries for Egg Allergy

About this section
Disease Ontology : 12 A food allergy that is an allergy or hypersensitivity to dietary substances from the yolk or whites of eggs, causing an overreaction of the immune system which may lead to severe physical symptoms.

MalaCards based summary : Egg Allergy, also known as egg hypersensitivity, is related to yellow fever and cytokine deficiency. An important gene associated with Egg Allergy is IGHE (Immunoglobulin Heavy Constant Epsilon), and among its related pathways/superpathways are PAK Pathway and Allograft rejection. The drugs Antisecretory factor and Vaccines have been mentioned in the context of this disorder. Affiliated tissues include testes, skin and t cells, and related phenotypes are hematopoietic system and homeostasis/metabolism

Wikipedia : 74 Egg allergy is an immune hypersensitivity to proteins found in chicken eggs, and possibly goose, duck,... more...

Sources

Related Diseases for Egg Allergy

About this section

Diseases related to Egg Allergy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 348)
# Related Disease Score Top Affiliating Genes
1 yellow fever 30.8 IL5 IL4 CCR6
2 cytokine deficiency 30.6 IL5 IL13
3 rubella 30.5 IL5 IL4 IL10
4 ige responsiveness, atopic 29.9 IL5 IL4 IL13 IL10 IGHE
5 diphtheria 29.9 IL5 IL4 IL13
6 eosinophilic gastroenteritis 29.8 TSLP IL5 IL4 CCR6
7 tetanus 29.7 IL5 IL4 IL13 IL10
8 gastroenteritis 29.6 TSLP IL5 IL4 IL10
9 poliomyelitis 29.5 IL4 IL10 CD4
10 allergic rhinitis 29.5 IL5 IL4 IL13 IL10 IGHE
11 hypereosinophilic syndrome 29.5 IL5 IL4 IL13 IL10 IGHE
12 food allergy 29.3 IL5 IL4 IL13 IL10 IGHE FOXP3
13 milk allergy 29.3 LALBA IL5 IL4 IL13 IL10 IGHE
14 urticaria 29.2 IL5 IL4 IL13 IL10 IGHE ENPP3
15 cow milk allergy 29.2 LALBA IL5 IL4 IL10 FOXP3
16 diarrhea 29.1 IL5 IL13 IL10 FOXP3
17 esophagitis, eosinophilic, 1 29.1 TSLP IL5 IL4 IL13 FLG CCR6
18 dermatitis 29.0 TSLP IL5 IL4 IL13 IL10 IGHE
19 esophagitis 29.0 TSLP IL5 IL4 IL13 IL10
20 allergic conjunctivitis 28.9 IL5 IL4 IL13 IL10 IGHE FOXP3
21 conjunctivitis 28.9 IL5 IL4 IL13 IL10 IGHE FOXP3
22 autoimmune disease 28.8 IL5 IL4 IL13 IL10 FOXP3 CCR6
23 peanut allergy 28.5 PEDS1 PDCL IL5 IL4 IL13 IL10
24 rhinitis 28.5 TSLP IL5 IL4 IL13 IL10 IGHE
25 nut allergy 28.3 PEDS1 PDCL IL5 IL13 IGHE FLG
26 rheumatoid arthritis 28.1 IL4 IL13 IL10 FOXP3 FLG CD4
27 dermatitis, atopic 27.5 TSLP PEDS1 LALBA IL5 IL4 IL13
28 allergic hypersensitivity disease 27.4 TSLP PEDS1 LALBA IL5 IL4 IL13
29 respiratory allergy 27.3 TSLP PDCL IL5 IL4 IL13 IL10
30 asthma 27.1 TSLP IL5 IL4 IL13 IL10 IGHE
31 legume allergy 25.1 TSLP PEDS1 PDCL IL5 IL4 IL13
32 chicken egg allergy 12.8
33 influenza 10.6
34 idiopathic nephrotic syndrome 10.4 IL4 IGHE
35 measles 10.4
36 aztreonam allergy 10.4 IL5 IL13
37 atopic keratoconjunctivitis 10.4 IL5 IL4 IGHE
38 toxic oil syndrome 10.4 IL5 IL4 IGHE
39 angioimmunoblastic lymphadenopathy with dysproteinemia 10.4 IL5 IL13
40 mumps 10.4
41 vernal conjunctivitis 10.4 IL4 IGHE CCR6
42 respiratory syncytial virus infectious disease 10.4 IL5 IL13
43 cefaclor allergy 10.4 IL5 IL13
44 cefuroxime allergy 10.3 IL5 IL13
45 timothy grass allergy 10.3 PEDS1 PDCL
46 neurodermatitis 10.3 IL4 FLG
47 vegetable allergy 10.3 PEDS1 PDCL
48 scleritis 10.3 IL5 IL4 CCR6
49 loeffler syndrome 10.3 IL5 IL13
50 aneruptive fever 10.3 IL13 FOXP3

Graphical network of the top 20 diseases related to Egg Allergy:



Diseases related to Egg Allergy
Sources

Symptoms & Phenotypes for Egg Allergy

About this section

MGI Mouse Phenotypes related to Egg Allergy:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.1 CCR6 CD4 COPS7A ENPP3 FOXP3 IL10
2 homeostasis/metabolism MP:0005376 10.03 CCR6 CD4 COPS7A FOXP3 IL10 IL13
3 digestive/alimentary MP:0005381 9.97 CD4 ENPP3 FOXP3 IL10 IL13 IL4
4 immune system MP:0005387 9.93 CCR6 CD4 COPS7A ENPP3 FOXP3 IL10
5 integument MP:0010771 9.56 CD4 FOXP3 IL10 IL13 IL4 LALBA
6 respiratory system MP:0005388 9.17 ENPP3 FOXP3 IL10 IL13 IL4 IL5
Sources

Drugs & Therapeutics for Egg Allergy

About this section

Drugs for Egg Allergy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 51)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Antisecretory factor Phase 3
2 Vaccines Phase 2
3 Immunologic Factors Phase 2
4
Nitric Oxide Approved Phase 1 10102-43-9 145068
5
Sargramostim Approved, Investigational Phase 1 83869-56-1, 123774-72-1
6
Metronidazole Approved Phase 1 443-48-1 4173
7
Ipilimumab Approved Phase 1 477202-00-9
8 Molgramostim Investigational Phase 1 99283-10-0
9 Immunoglobulins Phase 1
10 Antibodies Phase 1
11 Immunoglobulins, Intravenous Phase 1
12 Respiratory System Agents Phase 1
13 Phosphodiesterase Inhibitors Phase 1
14 Anti-Asthmatic Agents Phase 1
15 Antioxidants Phase 1
16 Endothelium-Dependent Relaxing Factors Phase 1
17 Vasodilator Agents Phase 1
18 Bronchodilator Agents Phase 1
19 Protective Agents Phase 1
20 Antineoplastic Agents, Immunological Phase 1
21 Androgens Phase 1
22 Antibodies, Monoclonal Phase 1
23 Anti-Infective Agents Phase 1
24 Anti-Bacterial Agents Phase 1
25 Antiparasitic Agents Phase 1
26 Antiprotozoal Agents Phase 1
27 Rho(D) Immune Globulin Phase 1
28 gamma-Globulins Phase 1
29
Bupivacaine Approved, Investigational 2180-92-9, 38396-39-3 2474
30
Ethanol Approved 64-17-5 702
31
tannic acid Approved 1401-55-4
32
Benzocaine Approved, Investigational 94-09-7, 1994-09-7 2337
33
Fentanyl Approved, Illicit, Investigational, Vet_approved 437-38-7 3345
34
Propofol Approved, Investigational, Vet_approved 2078-54-8 4943
35
Ketamine Approved, Vet_approved 6740-88-1 3821
36 Pharmaceutical Solutions
37 Sulfalene
38 Bifidobacterium
39 Trace Elements
40 Micronutrients
41 Immunoglobulin E
42 Neurotransmitter Agents
43 Excitatory Amino Acid Antagonists
44 Anesthetics
45 Hypnotics and Sedatives
46 Narcotics
47 Anesthetics, General
48 Anesthetics, Intravenous
49 Analgesics
50 Analgesics, Opioid

Interventional clinical trials:

(show all 43)
# Name Status NCT ID Phase Drugs
1 The Effect of Tocilizumab on the Cellular Immune Response to Seasonal Influnza Vaccine in Patients With Rheumatoid Arthritis Unknown status NCT01980836 Phase 4
2 Phase 4 Study to Assess the Safety of Nasal Influenza Immunisation in Egg Allergic Children - a Multicentre Observational Study Completed NCT02111512 Phase 4 Administration of Live attenuated influenza vaccine (LAIV)
3 Basophil Activation Test (BAT) Sensitivity in Child Food Allergy Completed NCT01966640 Phase 4
4 Antisecretory Factor (AF) Effects on Intraocular-pressure: a Placebo-controlled Randomised Study Unknown status NCT02731118 Phase 3
5 Specific Oral Tolerance Induction in Children With Severe Egg Allergy: A Randomized Controlled Trial Using a 6 Months Protocol Completed NCT01379651 Phase 1, Phase 2
6 Flu Vaccine in Egg-allergic Patients Minimizing Injections Safety Trial Completed NCT01248208 Phase 1, Phase 2
7 Induction of Tolerance Through Early Introduction of Peanut in High-Risk Children (ITN032AD) Completed NCT00329784 Phase 2
8 The Persistence of Oral Tolerance Induction to Peanut and Its Immunological Basis (ITN049AD) Completed NCT01366846 Phase 2
9 Oral Desensitization to Egg With Subsequent Induction of Sustained Unresponsiveness for Egg-Allergic Children Using Baked Egg or Egg Oral Immunotherapy (OIT) Completed NCT01846208 Phase 2 Egg Oral Immunotherapy;Baked Egg
10 Short-Term Behavioral Effects of Cholesterol Therapy in Smith-Lemli-Opitz Syndrome Completed NCT00114634 Phase 2
11 Oral Desensitization to Egg With Subsequent Induction of Tolerance for Egg-Allergic Children (CoFAR 3) Completed NCT00461097 Phase 2 Egg oral immunotherapy;Control Group
12 A Randomized Phase II Study of a PSA-Based Vaccine in Patients With Localized Prostate Cancer Receiving Standard Radiotherapy Completed NCT00005916 Phase 2 rV-PSA;rF-PSA;rV-B7.1
13 Open Label, Randomized, Parallel-Group, Multi-Centre Study to Evaluate the Safety, Tolerability and Immunogenicity of Baxter H1N1 Vaccine and GlaxoSmithKline H1N1 Vaccine in Children 6 Months to 12 Years of Age Completed NCT00980850 Phase 2
14 Phase 2 Study of AR201 Oral Immunotherapy for Desensitization in Children, Adolescents, and Young Adults With Hen Egg Allergy Active, not recruiting NCT04056299 Phase 2
15 Use of an Orally Administered Antibody to Gluten to Prevent the Recurrence of Symptoms and Laboratory Parameters in Persons With Celiac Disease (Gluten Sensitive Enteropathy) Completed NCT01765647 Phase 1
16 Cardiopulmonary Function Assessment and NO Based Therapies for Patients With Hemolysis-Associated Pulmonary Hypertension Completed NCT00352430 Phase 1 Nitric Oxide/INP Pulse Delivery;Nitric Oxide/INO Pulse Delivery
17 Phase I Trial of a PSA Based Vaccine and an Anti-CTLA-4 Antibody in Adults With Metastatic Androgen Independent Prostrate Cancer Completed NCT00113984 Phase 1 MDX-010;Sargramostim
18 Randomized Controlled Double-Blind Trial of the Comparative Viremia, Immunogenicity and Safety of a 17-D Live Attenuated Yellow Fever Vaccine (YF-VAX)Given Alone or in Combination With Human Immune Globulin (Gama STAN S/D) Completed NCT00254826 Phase 1
19 The Utility of Food-Specific IgE Measured With the IMMULITE 2000 Assay to Predict Symptomatic Food Allergy Unknown status NCT01950533
20 Cow's Milk and Hen's Egg Hyposensitization in Adults Unknown status NCT02083471
21 Treatment of Egg Allergy in Children Through Oral Desensitization (EGG OIT) Completed NCT00597558 Egg white protein
22 Phase 4 Study to Assess the Safety of Nasal Influenza Immunisation in Egg Allergic Children - a Multicentre Observational Study Completed NCT01859039
23 Egg Oral Immunotherapy Completed NCT01489553
24 Multi-Centered, Randomized, Placebo-Controlled Trial of the Safety of Influenza Vaccine in Egg Allergic Children With a History of Anaphylaxis or Severe Allergy to Egg Completed NCT01264601
25 Pilot Project on Clinical Tolerance to a Live Attenuated Vaccine Against Influenza (Flumist®) in the Context of Influenza Vaccination in a Population Allergic to Eggs. Completed NCT02142491
26 The Effect of Per Oral Immunotherapy in Severe IgE Mediated Egg, Milk and Nut Allergy in Adults Completed NCT01822353
27 A Randomized, Controlled Trial of Endoscopic Ultrasound Guided Celiac Plexus Blockade (EUS-CPB) With Standard Plexus Injection vs. Direct Celiac Ganglia Block for Treatment of Pain in Chronic Pancreatitis. Completed NCT03070210
28 A Prospective Cohort Study of Immune Mechanisms, Genetic Factors, and Clinical and Environmental Characteristics Associated With the Occurrence and Clinical Outcome of Food Allergy (CoFAR2) Completed NCT00356174
29 Potential Allergens in Wine: Double Blind Placebo-controlled Trial and Basophil Activation Analysis Completed NCT00163735 Administration of wine fined with potential food allergens
30 Use of Probiotics Bifidobacterium Longum, Bifidobacterium Breve and Bifidobacterium Infantis in Treating Pediatric Food Allergy to Milk or Egg. Completed NCT03639337
31 Assessment and Prevalence of Gastrointestinal Dysfunction in Children With Mitochondrial Disorders (MD) Completed NCT01137240
32 Cracking the Egg Potential: Improving Young Child Nutrition in Ecuador Completed NCT02446873
33 Use of MCT Oil for Enhancement of Weight Loss in Obese Patients-Preliminary Phase 2002-291G Completed NCT00207272
34 The Effect of Per Oral Immunotherapy Treatment in Severe IgE Mediated Milk, Peanut and Egg Allergy in Adults Recruiting NCT03361072
35 Basophil Activation Test to Diagnose Food Allergy Recruiting NCT03309488
36 Egg Desensitization and Induction of Tolerance in Children Recruiting NCT04027465
37 Trapsgewijze Ei-tolerantie-inductie Bij Kippenei-allergische Kinderen (TETI Studie) Active, not recruiting NCT02487420
38 Humoral and Cellular Immune Responses in Hen's Egg Oral Immunotherapy Active, not recruiting NCT03744325
39 Effects of Early Introduction of Allergenic Foods Followed by Ad-libitum Consumption, on Food Allergic Sensitisation, Allergy and Measures of Child Health at 8 Years of Age in Exclusively Breastfed Infants Enrolling by invitation NCT03495583
40 The Effects ofComplementary Feeding of Eggs on Infant Developmentand Growth in Guatemala: The Saqmolo Study Not yet recruiting NCT04316221
41 Impact of Vaccination on Th2 Immunity in Infancy Terminated NCT02213341
42 Combined Ketamine/Propofol for Emergency Department Procedural Sedation Terminated NCT01126957 Ketamine;Placebo;Fentanyl;Propofol
43 Study of Gastroscopy Negative Dyspepsia - Effect of Acid-reducing Treatment and Information on Various Types of Dysmotility. Terminated NCT00437346 Lanzo Melt;Lanzo Melt

Search NIH Clinical Center for Egg Allergy

Cochrane evidence based reviews: egg hypersensitivity

Sources

Genetic Tests for Egg Allergy

About this section
Sources

Anatomical Context for Egg Allergy

About this section

MalaCards organs/tissues related to Egg Allergy:

40
Testes, Skin, T Cells, Prostate, Breast, B Cells, Colon
Sources

Publications for Egg Allergy

About this section

Articles related to Egg Allergy:

(show top 50) (show all 649)
# Title Authors PMID Year
1
Lipocalin-type prostaglandin D synthase and egg white cystatin react with IgE antibodies from children with egg allergy. 61 54
20179418 2010
2
Correlation between specific immunoglobulin E levels and the severity of reactions in egg allergic patients. 61 54
18257905 2008
3
The natural history of egg allergy. 61 54
18073126 2007
4
Specificity of IgE antibodies to sequential epitopes of hen's egg ovomucoid as a marker for persistence of egg allergy. 54 61
17573723 2007
5
Detection of four distinct groups of hen egg allergens binding IgE in the sera of children with egg allergy. 54 61
16045855 2005
6
Determination of food specific IgE levels over time can predict the development of tolerance in cow's milk and hen's egg allergy. 61 54
15316521 2004
7
Possible modes of allergen-specific sensitization and boosting in an atopic child. 54 61
12740528 2003
8
Prediction of tolerance on the basis of quantification of egg white-specific IgE antibodies in children with egg allergy. 54 61
12170273 2002
9
Cellular immune responses to ovalbumin and house dust mite in egg-allergic children. 54 61
11906334 2002
10
Cytokine production in children outgrowing hen egg allergy. 61 54
8955579 1996
11
Establishment and characterization of ovalbumin-specific T cell lines from patients with egg allergy. 54 61
8634518 1996
12
Allergenic epitopes of ovalbumin (OVA) in patients with hen's egg allergy: inhibition of basophil histamine release by haptenic ovalbumin peptide. 61 54
8608645 1996
13
[IgE production and gene expression of interleukin-4 and interferon-gamma by peripheral mononuclear cells in asthmatic children]. 54 61
7726752 1995
14
Identification of the disease-related T cell epitope of ovalbumin and epitope-targeted T cell inactivation in egg allergy. 61 54
7522686 1994
15
Egg white-specific IgE level as a tolerance marker in the follow up of egg allergy. 61 54
8034192 1994
16
[The production of B cell stimulating activity in peripheral blood mononuclear cells from allergic children with positive IgE RAST score to egg white]. 61 54
2053859 1991
17
Combined Effects of Lactobacillus rhamnosus and Egg Oral Immunotherapy in a Mouse Model of Egg Allergy. 61
32400134 2020
18
Pros and cons of pre-emptive screening programmes before peanut introduction in infancy. 61
32562634 2020
19
Gastric emptying: methodology and normal ranges for two commonly used meals in the UK. 61
32427698 2020
20
Induction of sustained unresponsiveness after egg oral immunotherapy compared to baked egg therapy in egg-allergic children. 61
32535135 2020
21
Utility of fresh egg skin prick test and egg-yolk specific IgE for outgrowth. 61
32526376 2020
22
Ovalbumin in breastmilk is associated with a decreased risk of IgE-mediated egg allergy in children. 61
31808162 2020
23
Egg Allergy in US Children. 61
32376485 2020
24
Ovomucoid epitope-specific repertoire of IgE, IgG4 , IgG1 , IgA1 , and IgD antibodies in egg-allergic children. 61
32391917 2020
25
Preventing food allergy in infancy and childhood: Systematic review of randomised controlled trials. 61
32396244 2020
26
A role for early oral exposure to house dust mite allergens through breast milk in IgE-mediated food allergy susceptibility. 61
31954775 2020
27
The frequency of cross-reactivity with various avian eggs among children with hen's egg allergy using skin prick test results: fewer sensitizations with pigeon and goose egg. 61
32007321 2020
28
Atopy patch test in children with cow's milk and hen's egg allergy: Do clinical symptoms matter? 61
32402621 2020
29
Are primary care physicians following National Institute of Allergy and Infectious Disease guidelines for the prevention of peanut allergy? A survey-based study. 61
32375960 2020
30
Risk Factors for Hen's Egg Allergy in Europe: EuroPrevall Birth Cohort. 61
31846795 2020
31
Daily baked egg intake may accelerate the development of tolerance to raw egg in egg-allergic children. 61
31758309 2020
32
Oral intervention of Lactobacillus pentosus S-PT84 attenuates the allergenic responses in a BALB/C mouse model of egg allergy. 61
32050111 2020
33
Diagnostic performance of IgE avidity for hen's egg allergy in young infants. 61
32268215 2020
34
Adverse events in patients with hen's-egg-allergy who passed scrambled egg challenge. 61
32311153 2020
35
The inhibitory activity of alginate against allergic reactions in an ovalbumin-induced mouse model. 61
32163080 2020
36
Endotoxin, food allergen sensitization, and food allergy: A complementary epidemiologic and experimental study. 61
31535385 2020
37
Effect of moderate to severe atopic dermatitis on the prognosis of egg allergy resolution. 61
32247308 2020
38
[Staphylococcal scalded skin syndrome in a pediatric patient with atopic dermatitis]. 61
31984705 2020
39
Immunoglobulin E-Mediated Food Allergies Differ in East Mediterranean Children Aged 0-2 Years. 61
32097952 2020
40
The Natural Course of Immediate-Type Cow's Milk and Egg Allergies in Children. 61
31752004 2020
41
Component-Resolved Diagnostic Study of Egg Allergy in Northern Chinese Children. 61
32258118 2020
42
Egg yolk augments type 2 immunity by activating innate cells. 61
31903504 2020
43
A structured graduated protocol with heat denatured eggs in the treatment of egg allergy. 61
31419328 2019
44
Determining Levers of Cost-effectiveness for Screening Infants at High Risk for Peanut Sensitization Before Early Peanut Introduction. 61
31860109 2019
45
Efficacy of the Enquiring About Tolerance (EAT) study among infants at high risk of developing food allergy. 61
31812184 2019
46
Implementation of Early Peanut Introduction Guidelines: It Takes a Village. 61
31563181 2019
47
Prevention of food allergy. 61
31690392 2019
48
Propofol use in children with allergies to egg, peanut, soybean or other legumes. 61
31077340 2019
49
Baked egg tolerance: is it possible to predict? 61
31513760 2019
50
Yellow fever vaccine and egg allergy. 61
31345456 2019
Sources

Variations for Egg Allergy

About this section
Sources

Expression for Egg Allergy

About this section
Search GEO for disease gene expression data for Egg Allergy.
Sources

Pathways for Egg Allergy

About this section

Pathways related to Egg Allergy according to GeneCards Suite gene sharing:

(show all 22)
# Super pathways Score Top Affiliating Genes
1
PAK Pathway 63
Show member pathways
 13.15 IL5 IL4 IL13 IL10 CD4 CCR6
2
Allograft rejection 1 36
Show member pathways
 12.68 IL5 IL4 IL13 IL10 FOXP3 CD4
3
T cell receptor signaling pathway 36
Show member pathways
 12.46 IL5 IL4 IL10 CSNK2B CD4
4
Immune response Fc epsilon RI pathway 22
Show member pathways
 12.42 IL5 IL4 IL13 IGHE
5
NF-kappaB Signaling 4
12.4 IL4 IL10 FOXP3 ENPP3
6
Th17 cell differentiation 36
Show member pathways
 12.38 IL5 IL4 IL13 IL10 FOXP3 CD4
7
JAK-STAT signaling pathway 36
Show member pathways
 12.31 TSLP IL5 IL4 IL13 IL10
8
Immune response IFN alpha/beta signaling pathway 22
Show member pathways
 12.11 IL5 IL4 IL13 IL10
9
Hematopoietic Stem Cells and Lineage-specific Markers 64
11.86 IL5 IL4 IL10 CD4
10
Interleukin-4 and 13 signaling 65
11.84 IL4 IL13 IL10 IGHE
11
Hematopoietic cell lineage 36
11.75 IL5 IL4 CD4
12
Glucocorticoid receptor regulatory network 1
11.66 IL5 IL4 IL13
13
Calcineurin-regulated NFAT-dependent transcription in lymphocytes 1
Show member pathways
 11.61 IL5 IL4 FOXP3
14
IL4-mediated signaling events 1
11.53 IL5 IL4 IL10 IGHE
15
Lung fibrosis 1
11.52 IL5 IL4 IL13
16
Interleukin-10 signaling 65
11.4 IL4 IL13 IL10
17
Development and heterogeneity of the ILC family 1
11.13 TSLP IL5 IL4 IL13
18
Th2 Differentiation 64
11.1 IL5 IL4 IL13 IL10 FOXP3 CD4
19
Innate Lymphoid Cells Differentiation 64
11.07 TSLP IL5 IL4 IL13 IL10 CD4
20
Cytokines and Inflammatory Response 1
11.02 IL5 IL4 IL13 IL10 CD4
21
OX40 Pathway 63
10.97 IL5 IL4 IL13 IL10
22
IL-9 Signaling and its Primary Biological Effects in Different Immune Cell Types 64
10.66 IL5 IL4 IL13
Sources

GO Terms for Egg Allergy

About this section

Cellular components related to Egg Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 external side of plasma membrane GO:0009897 9.35 IL13 IGHE ENPP3 CD4 CCR6
2 extracellular region GO:0005576 9.32 TSLP PTGDS LALBA IL5 IL4 IL13

Biological processes related to Egg Allergy according to GeneCards Suite gene sharing:

(show all 20)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription, DNA-templated GO:0045893 9.99 IL5 IL4 IL10 FOXP3 CD4
2 signal transduction GO:0007165 9.91 TSLP PDCL LALBA IL5 IL4 IL10
3 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.69 TSLP IL4 IL13
4 T cell activation GO:0042110 9.65 IL4 FOXP3 CD4
5 macrophage activation GO:0042116 9.58 IL4 IL13
6 positive regulation of interleukin-10 secretion GO:2001181 9.58 IL4 IL13
7 positive regulation of B cell proliferation GO:0030890 9.58 IL5 IL4 IL13
8 positive regulation of mast cell degranulation GO:0043306 9.57 IL4 IL13
9 negative regulation of tumor necrosis factor biosynthetic process GO:0042536 9.56 IL4 IL10
10 positive regulation of MHC class II biosynthetic process GO:0045348 9.55 IL4 IL10
11 negative regulation of inflammatory response GO:0050728 9.55 IL4 IL13 IL10 FOXP3 ENPP3
12 negative regulation of T-helper 17 cell differentiation GO:2000320 9.54 IL4 FOXP3
13 negative regulation of endothelial cell apoptotic process GO:2000352 9.54 IL4 IL13 IL10
14 positive regulation of interleukin-13 production GO:0032736 9.52 TSLP IL4
15 type 2 immune response GO:0042092 9.49 IL4 IL10
16 regulation of isotype switching GO:0045191 9.46 IL4 IL10
17 negative regulation of chronic inflammatory response GO:0002677 9.43 IL4 FOXP3
18 cytokine-mediated signaling pathway GO:0019221 9.43 IL5 IL4 IL13 IL10 IGHE CD4
19 negative regulation of complement-dependent cytotoxicity GO:1903660 9.32 IL4 IL13
20 immune response GO:0006955 9.17 IL5 IL4 IL13 IL10 IGHE CD4

Molecular functions related to Egg Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.02 TSLP IL5 IL4 IL13 IL10
Sources

Sources for Egg Allergy

About this section
3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Content
Loading form....