Aliases & Classifications for Egg Allergy

MalaCards integrated aliases for Egg Allergy:

Name: Egg Allergy 12 15
Egg Hypersensitivity 44
Allergy to Eggs 12
Allergies Egg 55

Classifications:



External Ids:

Disease Ontology 12 DOID:4377
MeSH 44 D021181
UMLS 73 C0559469

Summaries for Egg Allergy

Disease Ontology : 12 A food allergy that is an allergy or hypersensitivity to dietary substances from the yolk or whites of eggs, causing an overreaction of the immune system which may lead to severe physical symptoms.

MalaCards based summary : Egg Allergy, also known as egg hypersensitivity, is related to milk allergy and food allergy. An important gene associated with Egg Allergy is IL4 (Interleukin 4), and among its related pathways/superpathways are Immune response Fc epsilon RI pathway and Hematopoietic cell lineage. The drugs Vaccines and Sennoside A&B have been mentioned in the context of this disorder. Affiliated tissues include testes, skin and t cells.

Wikipedia : 76 Egg allergy is an immune hypersensitivity to proteins found in chicken eggs, and possibly goose, duck,... more...

Related Diseases for Egg Allergy

Diseases related to Egg Allergy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 92)
# Related Disease Score Top Affiliating Genes
1 milk allergy 29.9 IL4 IL5
2 food allergy 29.9 IL4 IL5
3 dermatitis 29.8 IGHE IL4 IL5
4 dermatitis, atopic 29.8 IGHE IL4 IL5
5 gastroenteritis 29.5 IL4 IL5
6 nut allergy 29.3 IL5 IQCE
7 chicken egg allergy 12.4
8 influenza 10.5
9 immunodeficiency with hyper-igm, type 1 10.4 IGHE IL4
10 hyper ige syndrome 10.4 IGHE IL4
11 vernal conjunctivitis 10.3 IGHE IL4
12 cough variant asthma 10.1 IL4 IL5
13 inflammatory bowel disease 4 10.1 IL4 IL5
14 scleritis 10.1 IL4 IL5
15 intrinsic asthma 10.1 IL4 IL5
16 angiostrongyliasis 10.1 IL4 IL5
17 trichinosis 10.1 IL4 IL5
18 apple allergy 10.1 IL4 IL5
19 non-suppurative otitis media 10.1 IL4 IL5
20 aging 10.1
21 eosinophilic meningitis 10.1 IL4 IL5
22 cercarial dermatitis 10.1 IL4 IL5
23 intestinal schistosomiasis 10.1 IL4 IL5
24 urinary schistosomiasis 10.1 IL4 IL5
25 chronic conjunctivitis 10.1 IL4 IL5
26 eosinophilic gastritis 10.1 IL4 IL5
27 kimura disease 10.1 IL4 IL5
28 chronic tic disorder 10.1 IL4 IL5
29 folliculitis 10.1 IL4 IL5
30 vernal keratoconjunctivitis 10.1 IL4 IL5
31 primary amebic meningoencephalitis 10.1 IL4 IL5
32 conjunctival disease 10.1 IL4 IL5
33 measles 10.1
34 yellow fever 10.1
35 allergic bronchopulmonary aspergillosis 10.1 IL4 IL5
36 enterobiasis 10.1 IL4 IL5
37 pulmonary eosinophilia 10.0 IL4 IL5
38 paranasal sinus disease 10.0 IL4 IL5
39 onchocerciasis 10.0 IL4 IL5
40 allergic conjunctivitis 10.0 IL4 IL5
41 nasal cavity disease 10.0 IL4 IL5
42 paracoccidioidomycosis 10.0 IL4 IL5
43 asthma 10.0
44 nose disease 10.0 IL4 IL5
45 parasitic helminthiasis infectious disease 10.0 IL4 IL5
46 upper respiratory tract disease 10.0 IL4 IL5
47 leukocyte disease 10.0 IL4 IL5
48 conjunctivitis 10.0 IL4 IL5
49 keratoconjunctivitis 10.0 IL4 IL5
50 allergic contact dermatitis 9.9 IL4 IL5

Graphical network of the top 20 diseases related to Egg Allergy:



Diseases related to Egg Allergy

Symptoms & Phenotypes for Egg Allergy

Drugs & Therapeutics for Egg Allergy

Drugs for Egg Allergy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 26)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Vaccines Phase 4,Phase 1,Phase 2,Not Applicable
2 Sennoside A&B Phase 2
3 Senna Nutraceutical Phase 2
4
Metronidazole Approved Phase 1 443-48-1 4173
5
Nitric Oxide Approved Phase 1 10102-43-9 145068 160954
6 Respiratory System Agents Phase 1
7 Neurotransmitter Agents Phase 1
8 Androgens Phase 1
9 Vasodilator Agents Phase 1
10 Anti-Asthmatic Agents Phase 1
11 Endothelium-Dependent Relaxing Factors Phase 1
12 Peripheral Nervous System Agents Phase 1
13 Antibodies Phase 1
14 Immunoglobulins Phase 1
15 Phosphodiesterase Inhibitors Phase 1
16 Antibodies, Monoclonal Phase 1
17 Anti-Infective Agents Phase 1
18 Antioxidants Phase 1
19 Protective Agents Phase 1
20 Antiparasitic Agents Phase 1
21 Antiprotozoal Agents Phase 1
22 Autonomic Agents Phase 1
23 Bronchodilator Agents Phase 1
24 Immunoglobulin E
25 Pharmaceutical Solutions Not Applicable
26 Hemagglutinins Not Applicable

Interventional clinical trials:

(show all 33)
# Name Status NCT ID Phase Drugs
1 Safety of Nasal Influenza Immunisation in Egg Allergic Children - The SNIFFLE 2 Study Completed NCT02111512 Phase 4 Administration of Live attenuated influenza vaccine (LAIV)
2 Basophil Activation Test (BAT) Sensitivity in Child Food Allergy Recruiting NCT01966640 Phase 4
3 FluMist in Egg Allergic Patients Unknown status NCT01248208 Phase 1, Phase 2
4 Time-limited Specific Oral Tolerance Induction in Children With Severe Egg Allergy Completed NCT01379651 Phase 1, Phase 2
5 Oral Immunotherapy for Childhood Egg Allergy Completed NCT00461097 Phase 2 Egg oral immunotherapy;Control Group
6 Promoting Tolerance to Peanut in High-Risk Children Completed NCT00329784 Phase 2
7 Persistence of Oral Tolerance to Peanut Completed NCT01366846 Phase 2
8 Short-term Behavioral Effects of Cholesterol Therapy in Smith-Lemli-Opitz Syndrome Completed NCT00114634 Phase 2
9 Accelerated Immunization to Induce Cytomegalovirus Immunity in Stem Cell Donors Completed NCT00353977 Phase 2
10 PSA-Based Vaccine and Radiotherapy to Treat Localized Prostate Cancer Completed NCT00005916 Phase 2 rV-PSA;rF-PSA;rV-B7.1
11 Baked Egg or Egg Oral Immunotherapy for Children With Egg Allergy Active, not recruiting NCT01846208 Phase 2 Egg Oral Immunotherapy;Baked Egg
12 Oral AGY for Celiac Disease Completed NCT01765647 Phase 1
13 Cardiopulmonary Function Assessment and NO-Based Therapies for Patients With Hemolysis-Associated Pulmonary Hypertension Completed NCT00352430 Phase 1 Nitric Oxide/INP Pulse Delivery;Nitric Oxide/INO Pulse Delivery
14 Vaccine and Antibody Treatment of Prostate Cancer Completed NCT00113984 Phase 1 MDX-010;Sargramostim
15 Cow's Milk and Hen's Egg Hyposensitization in Adults Unknown status NCT02083471 Not Applicable
16 Treatment of Egg Allergy in Children Through Oral Desensitization (EGG OIT) Completed NCT00597558 Not Applicable Egg white protein
17 Clinical Tolerance to a Live Attenuated Vaccine Against Influenza (Flumist®) in a Population Allergic to Eggs Completed NCT02142491
18 Safe Administration of Flu Vaccine to Egg Allergic Children Completed NCT01264601 Not Applicable
19 Egg Oral Immunotherapy Completed NCT01489553
20 Safety of Nasal Influenza Immunisation in Egg Allergic Children Completed NCT01859039
21 Hydrolyzed Egg and Tolerance Induction Completed NCT01526863 Not Applicable
22 An Observational Study of Childhood Food Allergy Completed NCT00356174
23 Immunologic Profile of Children With Severe Allergies to Peanuts and Nuts After Induction of Tolerance Completed NCT01996774
24 Research in Skin Inflammation Completed NCT00026741
25 Impact of Vaccination on Th2 Immunity in Infancy Completed NCT02213341
26 Potential Allergens in Wine: Double-blind Placebo-controlled Trial Completed NCT00163735 Not Applicable Administration of wine fined with potential food allergens
27 The Effect of Per Oral Immunotherapy in Severe Milk, Peanut and Egg Allergy in Adults Recruiting NCT03361072 Not Applicable
28 Gradual Egg-tolerance Induction in Hen's Egg Allergic Children Recruiting NCT02487420 Not Applicable
29 Basophil Activation Test to Diagnose Food Allergy Recruiting NCT03309488
30 The Utility of Food-Specific IgE Measured With the IMMULITE 2000 Assay to Predict Symptomatic Food Allergy Active, not recruiting NCT01950533
31 The Effect of Per Oral Immunotherapy in Severe IgE Mediated Egg, Milk, and Nut Allergy in Adults Active, not recruiting NCT01822353 Not Applicable
32 Intranasal Diagnostics in Food Allergy: a Feasibility Study Enrolling by invitation NCT02159833 Not Applicable
33 Influenza Vaccine Post Allogeneic Transplant Terminated NCT01215981 Not Applicable

Search NIH Clinical Center for Egg Allergy

Cochrane evidence based reviews: egg hypersensitivity

Genetic Tests for Egg Allergy

Anatomical Context for Egg Allergy

MalaCards organs/tissues related to Egg Allergy:

41
Testes, Skin, T Cells, Prostate, Breast

Publications for Egg Allergy

Articles related to Egg Allergy:

(show top 50) (show all 228)
# Title Authors Year
1
Timing of regular egg intake for prevention of egg allergy. ( 29146009 )
2018
2
Egg-specific IgE and basophil activation but not egg-specific T-cell counts correlate with phenotypes of clinical egg allergy. ( 29518422 )
2018
3
A 10-year review found increasing incidence trends of emergency egg allergy reactions and food-induced anaphylaxis in children. ( 29920760 )
2018
4
The Oral Provocation Test for Raw Egg in Patients with Hen Egg Allergy. ( 29874663 )
2018
5
Debates in Allergy Medicine: Does oral immunotherapyA shorten the duration of milk and egg allergy?A The pro argument. ( 29977438 )
2018
6
Debates in Allergy Medicine: Oral immunotherapy shortens the duration of milk and egg allergy - the con argument. ( 29977439 )
2018
7
Early-life gut microbiome and egg allergy. ( 29318631 )
2018
8
Clinical and immunological profile of children aged 5-9 years with persistent egg allergy before oral immunotherapy with egg. A multicenter, randomized controlled trial of the Spanish Society of Pediatric Allergy, Asthma and Clinical Immunology (SEICAP). ( 29804794 )
2018
9
Oral and sublingual immunotherapy for egg allergy. ( 29676439 )
2018
10
The effect of oral immunotherapy treatment in severe IgE mediated milk, peanut, and egg allergy in adults. ( 29542268 )
2018
11
Development of Food Protein-Induced Enterocolitis Syndrome (FPIES) to egg following Immunoglobulin E (IgE)-mediated egg allergy<sup/>. ( 29859249 )
2018
12
Acquisition of tolerance to egg allergy in a child with repeated egg-induced acute pancreatitis. ( 29754972 )
2018
13
Are both early egg introduction and eczema treatment necessary for primary prevention of egg allergy? ( 29522845 )
2018
14
Search for a Novel Allergen in Hen's Egg Allergy Using an IgE Immunoblotting Assay. ( 29669337 )
2018
15
Oral immunotherapy in children with IgE-mediated hen's egg allergy: Follow-ups at 2.5 and 7 years. ( 29070273 )
2017
16
Egg allergy prevention. ( 29205663 )
2017
17
Association Between Family Characteristics and the Effect of Timing of Regular Egg Introduction in Infant Egg Allergy. ( 28346598 )
2017
18
Component-resolved diagnostics in Thai children with cow's milk and egg allergy. ( 28364406 )
2017
19
Eosinophilic Esophagitis After Egg Oral Immunotherapy in an Adult With Egg-Allergy and Egg-Bird Syndrome. ( 28731415 )
2017
20
Hydrolysed ovalbumin offers more effective preventive and therapeutic protection against egg allergy than the intact protein. ( 28763132 )
2017
21
Update on oral immunotherapy for egg allergy. ( 28696863 )
2017
22
A successful case of egg allergy tolerance achieved at a local clinic. ( 28216056 )
2017
23
Food Protein-Induced Enterocolitis Syndrome in Response to Quail's Egg in a Child Without Hen's Egg Allergy. ( 29199963 )
2017
24
How to prevent egg allergy. ( 28232461 )
2017
25
The Pathogenesis of Rheumatoid Arthritis is Associated with Milk or Egg Allergy. ( 27011946 )
2016
26
Debates in allergy medicine: baked milk and egg ingestion accelerates resolution of milk and egg allergy. ( 26839628 )
2016
27
Relationship between specific IgE to egg components and natural history of egg allergy in Danish children. ( 27565949 )
2016
28
Safety and Efficacy of Low-Dose Oral Immunotherapy for Hen's Egg Allergy in Children. ( 28049193 )
2016
29
Two-step egg introduction for prevention of egg allergy in high-risk infants with eczema (PETIT): a randomised, double-blind, placebo-controlled trial. ( 27939035 )
2016
30
Influenza vaccination and egg allergy: another step forward. ( 27012268 )
2016
31
Randomized controlled trial of early regular egg intake to prevent egg allergy. ( 27554812 )
2016
32
A randomized trial of egg introduction from 4A months of age in infants at risk for egg allergy. ( 27742394 )
2016
33
Transcriptional Profiling of Egg Allergy and Relationship to Disease Phenotype. ( 27788149 )
2016
34
Randomized Controlled Trial of Oral Immunotherapy for Egg Allergy in Japanese patients. ( 27914210 )
2016
35
Predictive values of egg specific IgE by two commonly used assay systems for the diagnosis of egg allergy in young children: a prospective multicenter study. ( 27061295 )
2016
36
Comparison of ImmunoCAP and Immulite serum specific IgE assays for the assessment of egg allergy. ( 27293451 )
2016
37
Matrix effect on baked egg tolerance in children with IgE-mediated hen's egg allergy. ( 27019388 )
2016
38
Consultation with registered dietitian to prevent accidental reactions to food: insight from an egg allergy influenza vaccination cohort. ( 28000691 )
2016
39
Protein-losing enteropathy and erythema caused by egg allergy in a breast-fed infant. ( 26818703 )
2016
40
Natural history of immediate-type hen's egg allergy in Japanese children. ( 26666473 )
2016
41
Heated egg yolk challenge predicts the natural course of hen's egg allergy: a retrospective study. ( 27777641 )
2016
42
Skin prick test and development of tolerance in egg allergy. ( 27506151 )
2016
43
Baked Milk and Egg Diets for Milk and Egg Allergy Management. ( 26617232 )
2016
44
Measles-Mumps-Rubella vaccine for children with egg allergy: Is admission for inpatient vaccination necessary? ( 27770112 )
2016
45
Is the Quantification of Antigen-Specific Basophil Activation a Useful Tool for Monitoring Oral Tolerance Induction in Children With Egg Allergy? ( 27012013 )
2016
46
Flu vaccine and egg allergy. ( 26507815 )
2015
47
Molecular diagnosis of egg allergy: an update. ( 25975845 )
2015
48
Factors associated with the course of egg allergy in children. ( 26505933 )
2015
49
Incidence and natural history of hen's egg allergy in the first 2 years of life - the EuroPrevall birth cohort study. ( 26514330 )
2015
50
Egg Allergy in Adolescent and Adult Patient Suffering from Atopic Dermatitis--Association with Concomitant Allergic Diseases. ( 26454801 )
2015

Variations for Egg Allergy

Expression for Egg Allergy

Search GEO for disease gene expression data for Egg Allergy.

Pathways for Egg Allergy

GO Terms for Egg Allergy

Cellular components related to Egg Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.35 CSNK2B IGHE IL4 IL5 PTGDS
2 cilium GO:0005929 8.8 ARL2BP CSNK2B IQCE

Biological processes related to Egg Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.33 IGHE IL4 IL5
2 cytokine-mediated signaling pathway GO:0019221 9.13 IGHE IL4 IL5
3 positive regulation of B cell proliferation GO:0030890 8.62 IL4 IL5

Sources for Egg Allergy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....