Egg Allergy disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Egg Allergy

MalaCards integrated aliases for Egg Allergy:

Name: Egg Allergy ¹¹ ¹⁴ ¹⁶ ⁷⁵

Egg Hypersensitivity ⁴³

Allergy to Eggs ¹¹

Allergies Egg ⁵³

Classifications:

MalaCards categories:
Anatomical: Immune diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹¹ DOID:4377

MeSH ⁴³ D021181

NCIt ⁴⁹ C172313

SNOMED-CT ⁶⁸ 91930004

EFO ¹⁶ EFO_0007248

UMLS ⁷¹ C0559469

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Summaries for Egg Allergy

Disease Ontology: ¹¹ A food allergy that is an allergy or hypersensitivity to dietary substances from the yolk or whites of eggs, causing an overreaction of the immune system which may lead to severe physical symptoms.

MalaCards based summary: Egg Allergy, also known as egg hypersensitivity, is related to rubella and angioedema. An important gene associated with Egg Allergy is IGHE (Immunoglobulin Heavy Constant Epsilon), and among its related pathways/superpathways are Cytokine Signaling in Immune system and PAK Pathway. The drugs Vaccines and Propofol have been mentioned in the context of this disorder. Affiliated tissues include skin, t cells and breast, and related phenotypes are immune system and no phenotypic analysis

Wikipedia: ⁷⁵ Egg allergy is an immune hypersensitivity to proteins found in chicken eggs, and possibly goose, duck,... more...

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Related Diseases for Egg Allergy

Diseases related to Egg Allergy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 445)

#	Related Disease	Score	Top Affiliating Genes
1	rubella	30.7	IL5 IL4 IL10
2	angioedema	30.3	IL5 IL10 IGHE
3	ige responsiveness, atopic	30.2	IL5 IL4 IL13 IL10 IGHE
4	gastroenteritis	30.2	IL5 IL4 IL10
5	eosinophilic gastroenteritis	30.1	IL5 IL4 IL13 IGHE
6	chronic urticaria	30.0	IL5 IGHE ENPP3
7	tetanus	29.9	IL5 IL4 IL13 IL10
8	diphtheria	29.9	IL5 IL4 IL13
9	hypereosinophilic syndrome	29.8	IL5 IL4 IL13 IL10 IGHE
10	allergic rhinitis	29.7	IL5 IL4 IL13 IL10 IGHE
11	chronic rhinitis	29.5	PEDS1 PDCL IL5 IL4 IL13 GHITM
12	dermatitis	29.4	TSLP IL5 IL4 IL13 IL10 IGHE
13	conjunctivitis	29.3	IL5 IL4 IL13 IL10 IGHE FOXP3
14	esophagitis, eosinophilic, 1	29.2	TSLP IL5 IL4 IL13 FLG CCR6
15	autoimmune disease	29.2	IL5 IL4 IL13 IL10 FOXP3 CCR6
16	urticaria	29.2	TSLP IL5 IL4 IL13 IL10 IGHE
17	esophagitis	29.1	TSLP IL5 IL4 IL13 IL10 FLG
18	rhinitis	29.1	TSLP IL5 IL4 IL13 IL10 IGHE
19	allergic disease	28.7	TSLP LALBA IL5 IL4 IL13 IL10
20	cow milk allergy	28.7	PEDS1 LALBA IL5 IL4 IL13 IL10
21	nut allergy	28.5	PEDS1 PDCL IL5 IL4 IL13 IGHE
22	rheumatoid arthritis	28.5	IL4 IL13 IL10 FOXP3 FLG CD4
23	allergic conjunctivitis	28.5	TSLP IL5 IL4 IL13 IL10 IGHE
24	occupational asthma	28.5	TSLP PEDS1 IL5 IL4 IL13 GHITM
25	milk allergy	28.4	TSLP PEDS1 LALBA IL5 IL4 IL13
26	asthma	28.2	TSLP IL5 IL4 IL13 IL10 IGHE
27	food allergy	28.1	TSLP PEDS1 PDCL LALBA IL5 IL4
28	dermatitis, atopic	28.0	TSLP PEDS1 LALBA IL5 IL4 IL13
29	allergic contact dermatitis	28.0	TSLP IL5 IL4 IL13 IL10 FOXP3
30	contact dermatitis	27.8	TSLP PEDS1 IL5 IL4 IL13 IL10
31	peanut allergy	27.2	TSLP PEDS1 PDCL IL5 IL4 IL13
32	respiratory allergy	26.9	TSLP PEDS1 PDCL IL5 IL4 IL13
33	chicken egg allergy	11.6
34	measles	10.4
35	mumps	10.4
36	enterobiasis	10.3	IL5 IL4
37	yellow fever	10.3
38	cercarial dermatitis	10.3	IL5 IL4
39	crab allergy	10.3	PEDS1 ENPP3
40	apricot allergy	10.3	PEDS1 ENPP3
41	photoallergic dermatitis	10.3	FLG CCR6
42	aztreonam allergy	10.3	IL5 IL13
43	dermatographia	10.3	IGHE ENPP3
44	nickel allergic contact dermatitis	10.3	IL5 IL13
45	kimura disease	10.3	IL5 IL4 IGHE
46	cephalosporin allergy	10.3	PEDS1 ENPP3
47	cefaclor allergy	10.3	IL5 IL13
48	respiratory syncytial virus infectious disease	10.2	IL5 IL13
49	oxirane allergy	10.2	PEDS1 ENPP3
50	vernal keratoconjunctivitis	10.2	IL4 IL13

Graphical network of the top 20 diseases related to Egg Allergy:

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Symptoms & Phenotypes for Egg Allergy

MGI Mouse Phenotypes related to Egg Allergy:

⁴⁵

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	immune system	MP:0005387	9.9	CCR6 CD4 ENPP3 FOXP3 IGHE IL10
2	no phenotypic analysis	MP:0003012	9.87	CD4 FOXP3 IGHE IL10 IL13 IL4
3	digestive/alimentary	MP:0005381	9.86	CD4 ENPP3 FOXP3 IL10 IL13 IL4
4	respiratory system	MP:0005388	9.5	ENPP3 FOXP3 IL10 IL13 IL4 IL5
5	hematopoietic system	MP:0005397	9.4	CCR6 CD4 ENPP3 FOXP3 IGHE IL10

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Drugs & Therapeutics for Egg Allergy

Drugs for Egg Allergy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 11)

#

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

1

Vaccines

Phase 4

2

Propofol

Approved, Investigational, Vet_approved

2078-54-8

4943

3

Immunoglobulins, Intravenous

4

Immunoglobulin E

5

Anesthetics, Intravenous

6

Soy Bean

7

Anesthetics, General

8

Anesthetics

9

Hypnotics and Sedatives

10

Immunoglobulins

11

Antibodies

Interventional clinical trials:

(show all 20)

#	Name	Status	NCT ID	Phase	Drugs
1	Phase 4 Study to Assess the Safety of Nasal Influenza Immunisation in Egg Allergic Children - a Multicentre Observational Study	Completed	NCT02111512	Phase 4	Administration of Live attenuated influenza vaccine (LAIV)
2	Induction of Tolerance Through Early Introduction of Peanut in High-Risk Children (ITN032AD)	Completed	NCT00329784	Phase 2
3	Flu Vaccine in Egg-allergic Patients Minimizing Injections Safety Trial	Completed	NCT01248208	Phase 1, Phase 2
4	The Persistence of Oral Tolerance Induction to Peanut and Its Immunological Basis (ITN049AD)	Completed	NCT01366846	Phase 2
5	Specific Oral Tolerance Induction in Children With Severe Egg Allergy: A Randomized Controlled Trial Using a 6 Months Protocol	Completed	NCT01379651	Phase 1, Phase 2
6	Phase 2 Study of AR201 Oral Immunotherapy for Desensitization in Children, Adolescents, and Young Adults With Hen Egg Allergy	Terminated	NCT04056299	Phase 2
7	Cow's Milk and Hen's Egg Hyposensitization in Adults	Unknown status	NCT02083471
8	Basophil Activation Test to Diagnose Food Allergy	Unknown status	NCT03309488
9	The Utility of Food-Specific IgE Measured With the IMMULITE 2000 Assay to Predict Symptomatic Food Allergy	Completed	NCT01950533
10	Pilot Project on Clinical Tolerance to a Live Attenuated Vaccine Against Influenza (Flumist®) in the Context of Influenza Vaccination in a Population Allergic to Eggs.	Completed	NCT02142491
11	Multi-Centered, Randomized, Placebo-Controlled Trial of the Safety of Influenza Vaccine in Egg Allergic Children With a History of Anaphylaxis or Severe Allergy to Egg	Completed	NCT01264601
12	Treatment of Egg Allergy in Children Through Oral Desensitization (EGG OIT)	Completed	NCT00597558		Egg white protein
13	Phase 4 Study to Assess the Safety of Nasal Influenza Immunisation in Egg Allergic Children - a Multicentre Observational Study	Completed	NCT01859039
14	A Prospective Cohort Study of Immune Mechanisms, Genetic Factors, and Clinical and Environmental Characteristics Associated With the Occurrence and Clinical Outcome of Food Allergy (CoFAR2)	Completed	NCT00356174
15	Egg Oral Immunotherapy	Completed	NCT01489553
16	Incidence of Perioperative Hypersensitivity Reactions to Propofol in Children Allergic to Egg and/or Soy	Completed	NCT04839666		Propofol
17	Gradual Egg-tolerance Induction in Hen's Egg Allergic Children Who Tolerate Baked Egg (TETI-II Study)	Recruiting	NCT04677790
18	The Effect of Per Oral Immunotherapy Treatment in Severe IgE Mediated Milk, Peanut and Egg Allergy in Adults	Active, not recruiting	NCT03361072
19	Trapsgewijze Ei-tolerantie-inductie Bij Kippenei-allergische Kinderen (TETI Studie)	Active, not recruiting	NCT02487420
20	Randomised Controlled Multicentre Trial on the Clinical Impact of the Basophil Activation Test and the Mast Cell Activation Test as Food Allergy Biomarkers in Children and Young People	Not yet recruiting	NCT05309772

Search NIH Clinical Center for Egg Allergy

Cochrane evidence based reviews: egg hypersensitivity

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Genetic Tests for Egg Allergy

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Anatomical Context for Egg Allergy

Organs/tissues related to Egg Allergy:

MalaCards : Skin, T Cells, Breast, Thymus, Liver

Sources

Publications for Egg Allergy

Articles related to Egg Allergy:

(show top 50) (show all 754)

#	Title	Authors	PMID	Year
1	Lipocalin-type prostaglandin D synthase and egg white cystatin react with IgE antibodies from children with egg allergy. ⁵³ ⁶²	Suzuki M...Seishima M	20179418	2010
2	Correlation between specific immunoglobulin E levels and the severity of reactions in egg allergic patients. ⁵³ ⁶²	Benhamou AH...Eigenmann PA	18257905	2008
3	The natural history of egg allergy. ⁵³ ⁶²	Savage JH...Wood RA	18073126	2007
4	Specificity of IgE antibodies to sequential epitopes of hen's egg ovomucoid as a marker for persistence of egg allergy. ⁵³ ⁶²	Jarvinen KM...Sampson HA	17573723	2007
5	Detection of four distinct groups of hen egg allergens binding IgE in the sera of children with egg allergy. ⁵³ ⁶²	Walsh BJ...Howden ME	16045855	2005
6	Determination of food specific IgE levels over time can predict the development of tolerance in cow's milk and hen's egg allergy. ⁵³ ⁶²	Shek LP...Sampson HA	15316521	2004
7	Possible modes of allergen-specific sensitization and boosting in an atopic child. ⁵³ ⁶²	Reininger R...Spitzauer S	12740528	2003
8	Prediction of tolerance on the basis of quantification of egg white-specific IgE antibodies in children with egg allergy. ⁵³ ⁶²	Boyano-Martinez T...Martin-Esteban M	12170273	2002
9	Cellular immune responses to ovalbumin and house dust mite in egg-allergic children. ⁵³ ⁶²	Ng TW...Prescott SL	11906334	2002
10	Cytokine production in children outgrowing hen egg allergy. ⁵³ ⁶²	Noma T...Baba M	8955579	1996
11	Establishment and characterization of ovalbumin-specific T cell lines from patients with egg allergy. ⁵³ ⁶²	Katsuki T...Niimi H	8634518	1996
12	Allergenic epitopes of ovalbumin (OVA) in patients with hen's egg allergy: inhibition of basophil histamine release by haptenic ovalbumin peptide. ⁵³ ⁶²	Honma K...Niimi H	8608645	1996
13	[IgE production and gene expression of interleukin-4 and interferon-gamma by peripheral mononuclear cells in asthmatic children]. ⁵³ ⁶²	Mukoyama T...Noma T	7726752	1995
14	Identification of the disease-related T cell epitope of ovalbumin and epitope-targeted T cell inactivation in egg allergy. ⁵³ ⁶²	Shimojo N...Niimi H	7522686	1994
15	Egg white-specific IgE level as a tolerance marker in the follow up of egg allergy. ⁵³ ⁶²	Crespo JF...Martin Esteban M	8034192	1994
16	[The production of B cell stimulating activity in peripheral blood mononuclear cells from allergic children with positive IgE RAST score to egg white]. ⁵³ ⁶²	Moroi T	2053859	1991
17	Food allergy in Sri Lanka - A comparative study. ⁶²	de Silva R...Dasanayake D	36474913	2022
18	Prospective evaluation of tolerance to unheated milk-boiled egg after baked milk-egg tolerance under 2 years. ⁶²	Cogurlu MT...Acar HC	35779844	2022
19	Avoiding avoidance in milk and egg allergy. ⁶²	Wong D...Upton JEM	36464391	2022
20	Tree nut introduction in infants with peanut and/or egg allergy. ⁶²	Payne J...Perrett KP	36347470	2022
21	Phenotyping of immediate-type food allergies based on 10 years of research: A latent class analysis. ⁶²	Takahashi K...Ebisawa M	36433852	2022
22	Food-specific immunoglobulin A does not correlate with natural tolerance to peanut or egg allergens. ⁶²	Liu EG...Eisenbarth SC	36383680	2022
23	Early Peanut Introduction in Primary Care: Evaluation of a Multi-Component Intervention. ⁶²	Daley MF...Rehring SMA	36410601	2022
24	Protease-digested egg-white products induce oral tolerance in mice but elicit little IgE production upon epicutaneous exposure. ⁶²	Yamada A...Matsumoto K	35443911	2022
25	Bronchial hyperresponsiveness and asthma during oral immunotherapy for egg or peanut allergy in children. ⁶²	Burman J...Makela MJ	36246730	2022
26	Delayed egg introduction beyond infancy and increased egg allergy risk in childhood. ⁶²	Martone GM...Wen X	36190149	2022
27	An Origami Paper-Based Biosensor for Allergen Detection by Chemiluminescence Immunoassay on Magnetic Microbeads. ⁶²	Lazzarini E...Mirasoli M	36290961	2022
28	Home Introduction of Baked Egg After Oral Food Challenge. ⁶²	Kotwal M...Wood RA	36243403	2022
29	Single-dose AAV vector gene immunotherapy to treat food allergy. ⁶²	Gonzalez-Visiedo M...Markusic DM	35990748	2022
30	Association of egg protein levels in dust with allergy status and related factors. ⁶²	Kojima R...Yamagata Z	36168729	2022
31	The natural history of peanut and egg allergy in children up to age 6 years in the HealthNuts population-based longitudinal study. ⁶²	Peters RL...Koplin JJ	35597613	2022
32	Potential of Egg as Complementary Food to Improve Nutrient Intake and Dietary Diversity. ⁶²	Faber M...Smuts CM	36014905	2022
33	The adverse reactions to vaccines practice parameter 10 years on-what have we learned? ⁶²	Kelso JM	35101646	2022
34	Prevalence of IgE-mediated cow milk, egg, and peanut allergy in young Singapore children. ⁶²	Lee AJ...Lee BW	35966156	2022
35	Patterns of allergenic food introduction in Los Angeles inner-city children. ⁶²	Kwong KY...Scott L	35966161	2022
36	Early food intervention and skin emollients to prevent food allergy in young children (PreventADALL): a factorial, multicentre, cluster-randomised trial. ⁶²	Skjerven HO...Lodrup Carlsen KC	35753340	2022
37	Allergen immunotherapy and/or biologicals for IgE-mediated food allergy: A systematic review and meta-analysis. ⁶²	de Silva D...GA2LEN Food Allergy Guidelines Group	35001400	2022
38	B-cell receptor physical properties affect relative IgG1 and IgE responses in mouse egg allergy. ⁶²	Udoye CC...Manz RA	36114245	2022
39	Egg Allergy in Children and Weaning Diet. ⁶²	Caffarelli C...Ricci G	35458102	2022
40	Allergen-specific T cells and clinical features of food allergy: Lessons from CoFAR immunotherapy cohorts. ⁶²	Berin MC...Sampson HA	34653515	2022
41	Is oral food challenge useful to avoid complete elimination in Japanese patients diagnosed with or suspected of having IgE-dependent hen's egg allergy? A systematic review. ⁶²	Murai H...Ebisawa M	34663557	2022
42	Dietary Diversity during Early Infancy Increases Microbial Diversity and Prevents Egg Allergy in High-Risk Infants. ⁶²	Lee BR...Kim J	35573149	2022
43	BSACI 2021 guideline for the management of egg allergy. ⁶²	Johnston N...Roberts G	34862823	2022
44	BSACI 2021 guideline for the management of egg allergy. ⁶²	Byrne A...Hourihane JO	34808029	2022
45	Is hen's egg allergy decreasing among Japanese children in nurseries? ⁶²	Tanaka Y...Kusunoki T	35261340	2022
46	Clinical cross-reactivity to quail's egg in patients with hen's egg allergy. ⁶²	Mitomori M...Ebisawa M	35338729	2022
47	Assessment of egg and milk allergies among Indians by revalidating a food allergy predictive model. ⁶²	Laha A...Podder S	35399818	2022
48	Food allergy and hypersensitivity reactions in children and adults-A review. ⁶²	Tedner SG...Nilsson C	34875122	2022
49	The association between environmental greenness and the risk of food allergy: A population-based study in Melbourne, Australia. ⁶²	Peters RL...Mavoa S	35212044	2022
50	[ANAPHYLACTIC REACTION TO LYSOZYME CHLORIDE-INCLUDING DEODORANT SPRAY IN A CHILD WITH EGG ALLERGY]. ⁶²	Saigano K...Ohya Y	35296604	2022

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Genes for Egg Allergy

Genes related to Egg Allergy (0 elite genes):

(show all 17)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubMed IDs
1	IGHE	Immunoglobulin Heavy Constant Epsilon	Protein Coding	16.84	Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	17573723 20179418 18073126 (more) 7726752 16045855 8608645 18257905 12740528 8034192 8634518 15316521 12170273
2	IL4	Interleukin 4	Protein Coding	12.71	DISEASES inferred ¹⁴ Novoseek inferred ⁵³	8955579 9677601 2053859
3	CSNK2B	Casein Kinase 2 Beta	Protein Coding	11.58	DISEASES inferred ¹⁴ GeneCards inferred via : Publications (show sections)
4	IL5	Interleukin 5	Protein Coding	11.17	DISEASES inferred ¹⁴ Novoseek inferred ⁵³	7522686 11906334
5	PTGDS	Prostaglandin D2 Synthase	Protein Coding	9.79	DISEASES inferred ¹⁴ GeneCards inferred via : Publications (show sections)
6	PEDS1	Plasmanylethanolamine Desaturase 1	Protein Coding	8.35	DISEASES inferred ¹⁴
7	CCR6	C-C Motif Chemokine Receptor 6	Protein Coding	8.06	DISEASES inferred ¹⁴ ¹⁴
8	FLG	Filaggrin	Protein Coding	6.84	DISEASES inferred ¹⁴
9	LALBA	Lactalbumin Alpha	Protein Coding	6.58	DISEASES inferred ¹⁴
10	ENPP3	Ectonucleotide Pyrophosphatase/Phosphodiesterase 3	Protein Coding	6.38	DISEASES inferred ¹⁴
11	IL13	Interleukin 13	Protein Coding	6.33	DISEASES inferred ¹⁴
12	FOXP3	Forkhead Box P3	Protein Coding	6.14	DISEASES inferred ¹⁴
13	IL10	Interleukin 10	Protein Coding	6.07	DISEASES inferred ¹⁴
14	TSLP	Thymic Stromal Lymphopoietin	Protein Coding	6.07	DISEASES inferred ¹⁴
15	PDCL	Phosducin Like	Protein Coding	5.95	DISEASES inferred ¹⁴
16	CD4	CD4 Molecule	Protein Coding	5.81	DISEASES inferred ¹⁴
17	GHITM	Growth Hormone Inducible Transmembrane Protein	Protein Coding	5.7	DISEASES inferred ¹⁴

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Variations for Egg Allergy

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Expression for Egg Allergy

Search GEO for disease gene expression data for Egg Allergy.

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Pathways for Egg Allergy

Pathways related to Egg Allergy according to GeneCards Suite gene sharing:

(show all 23)

#	Super pathways	Score	Top Affiliating Genes
1	Cytokine Signaling in Immune system ⁶⁶ Show member pathways Signaling by Interleukins ⁶⁶	13.16	TSLP IL5 IL4 IL13 IL10 CD4
2	PAK Pathway ⁶⁴ Show member pathways Antioxidant Action of Vitamin-C ⁶⁴ Epithelial Adherens Junctions ⁶⁴	13.13	IL5 IL4 IL13 IL10 CD4 CCR6
3	NF-kappaB Signaling ³	12.4	IL4 IL10 FOXP3 ENPP3
4	T-cell activation SARS-CoV-2 ⁷⁴ Show member pathways T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection ⁷⁴	11.98	IL5 IL4 IL10 CD4
5	Hematopoietic Stem Cells and Lineage-specific Markers ⁶⁵	11.84	CD4 IL10 IL4 IL5
6	Interleukin-4 and Interleukin-13 signaling ⁶⁶	11.79	IL4 IL13 IL10
7	Allograft rejection ⁷⁴	11.77	IL5 IL4 IL13 IL10 FOXP3
8	Glucocorticoid receptor regulatory network ⁶¹	11.63	IL13 IL4 IL5
9	Th17 cell differentiation pathway ⁷⁴	11.57	IL4 FOXP3 CD4
10	AP-1 transcription factor network ⁶¹	11.56	IL5 IL4 IL10
11	Calcineurin-regulated NFAT-dependent transcription in lymphocytes ⁶¹ Show member pathways Calcium signaling in the CD4+ TCR pathway ⁶¹	11.54	IL5 IL4 FOXP3
12	Lung fibrosis ⁷⁴	11.5	IL5 IL4 IL13
13	IL4-mediated signaling events ⁶¹	11.46	IL5 IL4 IL10
14	Inflammatory bowel disease signaling ⁷⁴ Show member pathways Ulcerative colitis signaling ⁷⁴	11.43	FOXP3 IL10 IL13 IL4 IL5
15	THC Differentiation Pathway ⁶⁴	11.39	IL4 IL10 CD4
16	Development and heterogeneity of the ILC family ⁷⁴	11.24	TSLP IL5 IL4 IL13
17	Immune infiltration in pancreatic cancer ⁷⁴	11.1	IL5 IL4 IL13 IL10
18	Th2 Differentiation ⁶⁵	11.1	IL5 IL4 IL13 IL10 FOXP3 CD4
19	Innate Lymphoid Cells Differentiation ⁶⁵	11.07	TSLP IL5 IL4 IL13 IL10 CD4
20	OX40 Pathway ⁶⁴	11.04	IL5 IL4 IL13 IL10
21	Cytokines and inflammatory response ⁷⁴	11.02	IL5 IL4 IL13 IL10 CD4
22	Selective expression of chemokine receptors during T-cell polarization ⁷⁴	10.77	IL4 CD4
23	IL-9 Signaling and its Primary Biological Effects in Different Immune Cell Types ⁶⁵	10.71	IL5 IL4 IL13

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GO Terms for Egg Allergy

Cellular components related to Egg Allergy according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	extracellular region	GO:0005576	9.58	TSLP PTGDS LALBA IL5 IL4 IL13

Biological processes related to Egg Allergy according to GeneCards Suite gene sharing:

(show all 13)

#	Name	GO ID	Score	Top Affiliating Genes
1	signal transduction	GO:0007165	10.11	TSLP PDCL LALBA IL5 IL4 IL13
2	T cell activation	GO:0042110	9.99	IL4 FOXP3 CD4
3	positive regulation of B cell proliferation	GO:0030890	9.95	IL5 IL4 IL13
4	positive regulation of interleukin-10 production	GO:0032733	9.93	IL13 IL4 TSLP
5	negative regulation of endothelial cell apoptotic process	GO:2000352	9.85	IL4 IL13 IL10
6	negative regulation of T-helper 17 cell differentiation	GO:2000320	9.83	IL4 FOXP3
7	type 2 immune response	GO:0042092	9.8	IL4 IL10
8	immune response	GO:0006955	9.77	CCR6 CD4 IGHE IL10 IL13 IL4
9	regulation of isotype switching	GO:0045191	9.73	IL4 IL10
10	positive regulation of immunoglobulin production	GO:0002639	9.73	IL10 IL13 IL5
11	negative regulation of chronic inflammatory response	GO:0002677	9.71	IL4 FOXP3
12	negative regulation of complement-dependent cytotoxicity	GO:1903660	9.62	IL4 IL13
13	negative regulation of inflammatory response	GO:0050728	9.28	IL4 IL13 IL10 FOXP3 ENPP3

Molecular functions related to Egg Allergy according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	cytokine activity	GO:0005125	9.32	TSLP IL5 IL4 IL13 IL10

Sources

Sources for Egg Allergy

¹ BitterDB

² CDC

³ Cell Signaling Technology

⁴ ClinicalTrials

⁵ ClinVar

⁶ CNVD

⁷ Cochrane Library

⁸ Cosmic

⁹ dbSNP

¹⁰ DGIdb

¹¹ Disease Ontology

¹² diseasecard

¹³ DiseaseEnhancer

¹⁴ DISEASES

¹⁵ DrugBank

¹⁶ EFO

¹⁷ ExPASy

¹⁸ FMA

¹⁹ GARD

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ GenomeRNAi

²⁶ GEO DataSets

²⁷ GO

²⁸ GTR

²⁹ HMDB

³⁰ HPO

³¹ ICD10

³² ICD10 via Orphanet

³³ ICD11

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ LifeMap

³⁷ LncRNADisease

³⁸ LOVD

³⁹ MalaCards

⁴⁰ MedGen

⁴¹ MedlinePlus

⁴² MedlinePlus Genetics

⁴³ MeSH

⁴⁴ MESH via Orphanet

⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

⁴⁸ NCI

⁴⁹ NCIt

⁵⁰ NDF-RT

⁵¹ NIH Clinical Center

⁵² NINDS

⁵³ Novoseek

⁵⁴ Novus Biologicals

⁵⁵ ODiseA

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 08-Dec-2022)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubChem

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ WikiPathways

⁷⁵ Wikipedia

MCID: EGG001 MIFTS: 42	Egg Allergy Categories: Immune diseases	Data Licensing For inquiries, contact: [email protected]
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