Aliases & Classifications for Enamel Erosion

MalaCards integrated aliases for Enamel Erosion:

Name: Enamel Erosion 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:2497
ICD9CM 35 521.31
UMLS 73 C1456161

Summaries for Enamel Erosion

MalaCards based summary : Enamel Erosion is related to dentine erosion and teeth hard tissue disease. An important gene associated with Enamel Erosion is GPI (Glucose-6-Phosphate Isomerase), and among its related pathways/superpathways are BRCA1 Pathway and Transcription Ligand-dependent activation of the ESR1/SP pathway. The drugs sodium fluoride and Anti-Infective Agents have been mentioned in the context of this disorder. Affiliated tissues include testes, and related phenotypes are homeostasis/metabolism and mortality/aging

Related Diseases for Enamel Erosion

Graphical network of the top 20 diseases related to Enamel Erosion:



Diseases related to Enamel Erosion

Symptoms & Phenotypes for Enamel Erosion

MGI Mouse Phenotypes related to Enamel Erosion:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.43 GPI LPP MTF1 RASIP1 SMARCA2 SMARCA4
2 mortality/aging MP:0010768 9.1 GPI LPP MTF1 RASIP1 SMARCA2 SMARCA4

Drugs & Therapeutics for Enamel Erosion

Drugs for Enamel Erosion (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 7)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 sodium fluoride Approved Phase 3,Phase 2,Not Applicable 7681-49-4
2 Anti-Infective Agents Phase 3,Phase 2,Not Applicable
3 Anti-Infective Agents, Local Phase 3,Phase 2,Not Applicable
4 Cariostatic Agents Phase 3,Phase 2,Not Applicable
5 Fluorides Phase 3,Phase 2,Not Applicable
6 Listerine Phase 3,Phase 2,Not Applicable
7 Protective Agents Phase 3,Phase 2,Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Effect of Fluoride in a Dentifrice on Remineralization of Erosive Lesions Completed NCT01641237 Phase 3 sodium fluoride;no added fluoride in a silica base
2 Evaluation of a Test Mouthwash and Dentifrice Regimen in an In-situ Model of Dental Erosion Completed NCT01128972 Phase 2 Sodium fluoride;Sodium monoflurophosphate;Sterile water
3 Preliminary Clinical Study of Ultrasound to Measure Enamel Thickness Completed NCT01622920 Phase 1
4 In Vivo Investigation of Initial Stages of Enamel Erosion Completed NCT02533466 Not Applicable

Search NIH Clinical Center for Enamel Erosion

Genetic Tests for Enamel Erosion

Anatomical Context for Enamel Erosion

MalaCards organs/tissues related to Enamel Erosion:

41
Testes

Publications for Enamel Erosion

Articles related to Enamel Erosion:

(show top 50) (show all 155)
# Title Authors Year
1
New survey reveals lack of knowledge about enamel erosion. ( 29795513 )
2018
2
Effect of Mouthrinses containing Olive Oil, Fluoride, and Their Combination on Enamel Erosion: An in vitro Study. ( 29422460 )
2018
3
Influence of Surfactants and Fluoride against Enamel Erosion. ( 29874648 )
2018
4
Fluoride toothpastes containing micrometric or nano-sized sodium trimetaphosphate reduce enamel erosion in vitro. ( 29037096 )
2018
5
ATR-FTIR spectroscopy and I1-EDXRF spectrometry monitoring of enamel erosion caused by medicaments used in the treatment of respiratory diseases. ( 29134721 )
2018
6
Remineralizing effect of a zinc-hydroxyapatite toothpaste on enamel erosion caused by soft drinks: Ultrastructural analysis. ( 28828151 )
2017
7
Nd:YAG laser irradiation associated with fluoridated gels containing photo absorbers in the prevention of enamel erosion. ( 28500516 )
2017
8
A novel approach to study in situ enamel erosion and abrasion lesions. ( 28232081 )
2017
9
Frequency of Application of AmF/NaF/SnCl2 Solution and Its Potential in Controlling Human Enamel Erosion Progression: An in situ Study. ( 28125809 )
2017
10
Quantitative Swept-Source Optical Coherence Tomography of Early Enamel Erosion in vivo. ( 28637033 )
2017
11
In situ evaluation of fluoride-, stannous- and polyphosphate-containing solutions against enamel erosion. ( 28552363 )
2017
12
Protective effect of zinc-hydroxyapatite toothpastes on enamel erosion: An in vitro study. ( 28149475 )
2017
13
In vitro enamel erosion and abrasion-inhibiting effect of different fluoride varnishes. ( 28167334 )
2017
14
A New Laser-Processing Strategy for Improving Enamel Erosion Resistance. ( 28665779 )
2017
15
AmF/NaF/SnCl2 solution reduces in situ enamel erosion - profilometry and cross-sectional nanoindentation analysis. ( 28273206 )
2017
16
Effect of Fluoride Varnish Containing CPP-ACP on Preventing Enamel Erosion. ( 29109803 )
2017
17
Effects of tannin-fluoride and milk-fluoride mixture on human enamel erosion from inappropriately chlorinated pool water. ( 28904314 )
2017
18
Effect of CPP-ACP or a Potassium Nitrate Sodium Fluoride Dentifrice on Enamel Erosion Prevention. ( 28288296 )
2017
19
A new hand-held optical reflectometer to measure enamel erosion: correlation with surface hardness and calcium release. ( 27121129 )
2016
20
Influence of Calcium Phosphate and Apatite Containing Products on Enamel Erosion. ( 27430013 )
2016
21
A simple, sensitive and non-destructive technique for characterizing bovine dental enamel erosion: attenuated total reflection Fourier transform infrared spectroscopy. ( 27025266 )
2016
22
Analysis of the Early Stages and Evolution of Dental Enamel Erosion. ( 27224566 )
2016
23
Protective effects of a zinc-hydroxyapatite toothpaste on enamel erosion: SEM study. ( 28149449 )
2016
24
Toothpastes and enamel erosion/abrasion- impact of active ingredients and the particulate fraction. ( 27650640 )
2016
25
In situ effect of a CPP-ACP chewing gum on enamel erosion associated or not with abrasion. ( 27020912 )
2016
26
In vitro effect of low-fluoride toothpastes containing sodium trimetaphosphate on enamel erosion. ( 26964595 )
2016
27
In Vitro Effects of Resin Infiltration on Enamel Erosion Inhibition. ( 25587972 )
2015
28
In vitro effect of calcium-containing prescription-strength fluoride toothpastes on bovine enamel erosion under hyposalivation-simulating conditions. ( 25864237 )
2015
29
COa88 laser emission modes to control enamel erosion. ( 25988247 )
2015
30
In vitro effect of low-fluoride toothpastes containing sodium trimetaphosphate on enamel erosion. ( 26092765 )
2015
31
Protective effect of fluoride varnish and fluoride gel on enamel erosion: roughness, SEM-EDS, and A/-EDXRF studies. ( 25626779 )
2015
32
Protective effect of casein phosphopeptide-amorphous calcium phosphate on enamel erosion: Atomic force microscopy studies. ( 25917931 )
2015
33
Combined Tin-Containing Fluoride Solution and CO2 Laser Treatment Reduces Enamel Erosion in vitro. ( 26418736 )
2015
34
Effect of self-assembling peptide P11 -4 on enamel erosion: AFM and SEM studies. ( 26435410 )
2015
35
Enamel erosion and mechanical tooth wear in medieval Icelanders. ( 26358010 )
2015
36
Effect of High-Fluoride Dentifrice on Enamel Erosion Adjacent to Restorations In Vitro. ( 26266646 )
2015
37
Sequence of stannous and sodium fluoride solutions to prevent enamel erosion. ( 26454222 )
2015
38
Effect of sodium fluoride and stannous chloride associated with Nd:YAG laser irradiation on the progression of enamel erosion. ( 26227298 )
2015
39
Effect of home-bleaching gels modified by calcium and/or fluoride and the application of nano-hydroxyapatite paste on in vitro enamel erosion susceptibility. ( 26083582 )
2015
40
Effect of fluoride gels supplemented with sodium trimetaphosphate on enamel erosion and abrasion: in vitro study. ( 24581857 )
2014
41
The effect of saliva substitutes on enamel erosion in vitro. ( 24705070 )
2014
42
Calcium lactate pre-rinse increased fluoride protection against enamel erosion in a randomized controlled in situ trial. ( 24582799 )
2014
43
The CPP-ACP relieved enamel erosion from a carbonated soft beverage: an in vitro AFM and XRD study. ( 24581849 )
2014
44
Er:YAG laser irradiation to control the progression of enamel erosion: an in situ study. ( 24985348 )
2014
45
Combined effect of a fluoride-, stannous- and chitosan-containing toothpaste and stannous-containing rinse on the prevention of initial enamel erosion-abrasion. ( 24440712 )
2014
46
Fluoride varnishes containing calcium glycerophosphate: fluoride uptake and the effect on in vitro enamel erosion. ( 25416637 )
2014
47
Enamel erosion and prevention efficacy characterized by confocal laser scanning microscope. ( 24706542 )
2014
48
Benefits of a dentifrice containing 8% arginine, calcium carbonate, and sodium monofluorophosphate on enamel erosion. ( 24933796 )
2014
49
Three-dimensional profilometric assessment of early enamel erosion simulating gastric regurgitation. ( 24995810 )
2014
50
In vitro assessment of artificial saliva formulations on initial enamel erosion remineralization. ( 24269764 )
2014

Variations for Enamel Erosion

Expression for Enamel Erosion

Search GEO for disease gene expression data for Enamel Erosion.

Pathways for Enamel Erosion

Pathways related to Enamel Erosion according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
10.87 SMARCA2 SMARCA4
2
Show member pathways
10.47 SMARCA2 SMARCA4

GO Terms for Enamel Erosion

Cellular components related to Enamel Erosion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 SWI/SNF complex GO:0016514 9.16 SMARCA2 SMARCA4
2 nBAF complex GO:0071565 8.96 SMARCA2 SMARCA4
3 npBAF complex GO:0071564 8.62 SMARCA2 SMARCA4

Biological processes related to Enamel Erosion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transcription by RNA polymerase II GO:0006366 9.54 MTF1 SMARCA2 SMARCA4
2 positive regulation of transcription, DNA-templated GO:0045893 9.5 MTF1 SMARCA2 SMARCA4
3 negative regulation of cell growth GO:0030308 9.26 SMARCA2 SMARCA4
4 chromatin remodeling GO:0006338 9.16 SMARCA2 SMARCA4
5 response to cadmium ion GO:0046686 8.96 GPI MTF1
6 ATP-dependent chromatin remodeling GO:0043044 8.62 SMARCA2 SMARCA4

Molecular functions related to Enamel Erosion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 DNA-dependent ATPase activity GO:0008094 9.16 SMARCA2 SMARCA4
2 transcription coactivator activity GO:0003713 9.13 MTF1 SMARCA2 SMARCA4
3 hydrolase activity, acting on acid anhydrides GO:0016817 8.62 SMARCA2 SMARCA4

Sources for Enamel Erosion

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....