MCID: ENC001
MIFTS: 23

Encapsulated Thymoma

Categories: Cancer diseases, Endocrine diseases, Immune diseases

Aliases & Classifications for Encapsulated Thymoma

MalaCards integrated aliases for Encapsulated Thymoma:

Name: Encapsulated Thymoma 12 15 74

Classifications:



External Ids:

Disease Ontology 12 DOID:3278
NCIt 51 C7386
UMLS 74 C1333383

Summaries for Encapsulated Thymoma

MalaCards based summary : Encapsulated Thymoma is related to b cell prolymphocytic leukemia and richter's syndrome. An important gene associated with Encapsulated Thymoma is CD38 (CD38 Molecule), and among its related pathways/superpathways are Salivary secretion and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include b cells, pancreas and lung, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and Synthetic lethal with MLN4924 (a NAE inhibitor)

Related Diseases for Encapsulated Thymoma

Diseases related to Encapsulated Thymoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 51)
# Related Disease Score Top Affiliating Genes
1 b cell prolymphocytic leukemia 10.1 CD38 TP53
2 richter's syndrome 10.1 CD38 TP53
3 thymoma, familial 10.0
4 thymoma 10.0
5 invasive malignant thymoma 10.0 CD38 MME
6 acquired immunodeficiency syndrome 10.0 CD38 TP53
7 cervical carcinosarcoma 10.0 MME TP53
8 carcinosarcoma 10.0 MME TP53
9 adenosarcoma 10.0 MME TP53
10 plasma protein metabolism disease 10.0 CD38 MME
11 central nervous system hematologic cancer 10.0 MME TP53
12 breast benign neoplasm 10.0 MME TP53
13 thoracic benign neoplasm 10.0 MME TP53
14 eccrine sweat gland neoplasm 10.0 MME TP53
15 mixed cell type cancer 10.0 MME TP53
16 leukemia, acute lymphoblastic 3 10.0 MME TP53
17 uterine carcinosarcoma 10.0 MME TP53
18 acute lymphocytic leukemia 10.0 MME TP53
19 renal cell carcinoma, papillary, 1 10.0 MME TP53
20 endometrial stromal sarcoma 10.0 MME TP53
21 prolactin producing pituitary tumor 9.9 SST TP53
22 diffuse large b-cell lymphoma 9.9 MME TP53
23 pemphigus 9.9
24 paraneoplastic pemphigus 9.9
25 gastrointestinal system benign neoplasm 9.9 SST TP53
26 atrophic gastritis 9.9 SST TP53
27 pancreas disease 9.9 SST TP53
28 cell type benign neoplasm 9.9 SST TP53
29 merkel cell carcinoma 9.9 SST TP53
30 stomach disease 9.9 SST TP53
31 orbital plasma cell granuloma 9.9 MME SST
32 mantle cell lymphoma 9.9 MME TP53
33 ileum cancer 9.8 MME SST
34 endocrine gland cancer 9.8 SST TP53
35 b-cell lymphomas 9.8 MME TP53
36 meningioma, familial 9.8 SST TP53
37 gastrointestinal system disease 9.8 SST TP53
38 small cell cancer of the lung 9.8 SST TP53
39 clear cell renal cell carcinoma 9.8 MME TP53
40 pancreas adenocarcinoma 9.8 SST TP53
41 cll/sll 9.7 CD38 MME TP53
42 mature b-cell neoplasm 9.7 CD38 MME TP53
43 leukocyte disease 9.7 CD38 MME TP53
44 lymphocytic leukemia 9.7 CD38 MME TP53
45 myeloma, multiple 9.7 CD38 MME TP53
46 hematologic cancer 9.7 CD38 MME TP53
47 lymphoma, non-hodgkin, familial 9.7 CD38 MME TP53
48 leukemia, acute myeloid 9.7 CD38 MME TP53
49 diarrhea 9.7 MME SST
50 cholangiocarcinoma 9.6 MME TP53

Graphical network of the top 20 diseases related to Encapsulated Thymoma:



Diseases related to Encapsulated Thymoma

Symptoms & Phenotypes for Encapsulated Thymoma

GenomeRNAi Phenotypes related to Encapsulated Thymoma according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-1 9.02 SST TP53
2 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-2 9.02 CD38 SST TP53

MGI Mouse Phenotypes related to Encapsulated Thymoma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 immune system MP:0005387 8.92 CD38 MME SST TP53

Drugs & Therapeutics for Encapsulated Thymoma

Search Clinical Trials , NIH Clinical Center for Encapsulated Thymoma

Genetic Tests for Encapsulated Thymoma

Anatomical Context for Encapsulated Thymoma

MalaCards organs/tissues related to Encapsulated Thymoma:

42
B Cells, Pancreas, Lung, Breast, Pituitary, Myeloid

Publications for Encapsulated Thymoma

Articles related to Encapsulated Thymoma:

# Title Authors Year
1
Clinical-pathologic conference: cutaneous paraneoplastic pemphigus associated with benign encapsulated thymoma. ( 12579111 )
2003
2
Encapsulated thymoma metastasizing to a pectoralis major muscle. ( 12073605 )
2002

Variations for Encapsulated Thymoma

Expression for Encapsulated Thymoma

Search GEO for disease gene expression data for Encapsulated Thymoma.

Pathways for Encapsulated Thymoma

Pathways related to Encapsulated Thymoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.54 CD38 SST
2 11.32 CD38 MME
3 11.14 CD38 MME
4 10.82 CD38 MME
5 10.35 CD38 MME

GO Terms for Encapsulated Thymoma

Cellular components related to Encapsulated Thymoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 secretory granule membrane GO:0030667 8.62 CD38 MME

Biological processes related to Encapsulated Thymoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 replicative senescence GO:0090399 8.62 MME TP53

Sources for Encapsulated Thymoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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