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MERS
MCID: ENC065
MIFTS: 20
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Encephalitis/encephalopathy, Mild, with Reversible Myelin Vacuolization (MERS)
Categories:
Genetic diseases, Neuronal diseases
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MalaCards integrated aliases for Encephalitis/encephalopathy, Mild, with Reversible Myelin Vacuolization:
Characteristics:OMIM:57
Inheritance:
autosomal dominant
Miscellaneous:
onset in childhood episodes may be triggered by fever, infection, stress affected individuals have complete neurologic recovery within days to weeks brain imaging abnormalities are transient and return to normal no permanent neurologic sequelae two unrelated japanese families have been reported (last curated september 2018) Classifications: |
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OMIM
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57
MMERV is an episodic acute reversible encephalopathy that occurs in children and is frequently associated with a trigger, such as a febrile illness. Affected individuals have impaired consciousness, delirious behavior, and/or seizures with lip smacking or eye deviation. These changes are associated with white matter lesions in the brain that often occur in the splenium of the corpus callosum, but may occur in surrounding areas. The acute phase of the disorder can be treated with steroids, and most patients make a full neurologic recovery between episodes with no sequelae (summary by Kurahashi et al., 2018). (618113)
MalaCards based summary : Encephalitis/encephalopathy, Mild, with Reversible Myelin Vacuolization, also known as encephalitis/encephalopathy, mild, with reversible splenial lesion; mers, is related to severe acute respiratory syndrome and encephalopathy. An important gene associated with Encephalitis/encephalopathy, Mild, with Reversible Myelin Vacuolization is MYRF (Myelin Regulatory Factor). Affiliated tissues include brain, eye and lung. |
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MalaCards organs/tissues related to Encephalitis/encephalopathy, Mild, with Reversible Myelin Vacuolization:41
Brain,
Eye,
Lung,
Liver,
Prostate,
T Cells,
Myeloid
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Genes related to Encephalitis/encephalopathy, Mild, with Reversible Myelin Vacuolization (1 elite genes): - Elite gene
- Cancer Census gene in COSMIC
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ClinVar genetic disease variations for Encephalitis/encephalopathy, Mild, with Reversible Myelin Vacuolization:6
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Search
GEO
for disease gene expression data for Encephalitis/encephalopathy, Mild, with Reversible Myelin Vacuolization.
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