MCID: ENC014
MIFTS: 35

Enchondroma

Categories: Bone diseases, Rare diseases

Aliases & Classifications for Enchondroma

MalaCards integrated aliases for Enchondroma:

Name: Enchondroma 53 73

Classifications:



External Ids:

UMLS 73 C1704356

Summaries for Enchondroma

MalaCards based summary : Enchondroma is related to enchondromatosis, multiple, ollier type and multiple enchondromatosis, maffucci type, and has symptoms including pain An important gene associated with Enchondroma is IDH1 (Isocitrate Dehydrogenase (NADP(+)) 1, Cytosolic), and among its related pathways/superpathways are Carbon metabolism and Glutathione metabolism. Affiliated tissues include bone, bone marrow and breast.

Wikipedia : 76 An enchondroma is a cartilage cyst found in the bone marrow. Typically, enchondroma is discovered on an... more...

Related Diseases for Enchondroma

Diseases related to Enchondroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 59)
# Related Disease Score Top Affiliating Genes
1 enchondromatosis, multiple, ollier type 32.7 IDH1 IDH2
2 multiple enchondromatosis, maffucci type 32.7 IDH1 IDH2
3 chondrosarcoma 31.1 IDH1 IDH2
4 spindle cell hemangioma 29.8 IDH1 IDH2
5 metachondromatosis 11.7
6 chondroma 11.4
7 cervicofacial fibrochondroma 11.1
8 spondyloenchondrodysplasia 11.1
9 osteochondroma 10.2
10 breast cancer 10.0
11 hemangioma 10.0
12 malignant fibroxanthoma 10.0
13 chondroblastoma 10.0
14 histiocytoma 10.0
15 fibrous histiocytoma 10.0
16 interval angle-closure glaucoma 10.0 IDH1 IDH2
17 adult oligodendroglioma 10.0 IDH1 IDH2
18 oligodendroglioma 10.0 IDH1 IDH2
19 intracranial chondrosarcoma 10.0 IDH1 IDH2
20 cytogenetically normal acute myeloid leukemia 10.0 IDH1 IDH2
21 chondroblastic osteosarcoma 10.0 IDH1 IDH2
22 intraductal papilloma 10.0 IDH1 IDH2
23 pilocytic astrocytoma of cerebellum 10.0 IDH1 IDH2
24 periosteal chondrosarcoma 10.0 IDH1 IDH2
25 glioma susceptibility 1 10.0 IDH1 IDH2
26 adult astrocytic tumour 10.0 IDH1 IDH2
27 fibrillary astrocytoma 10.0 IDH1 IDH2
28 diffuse infiltrative lymphocytosis syndrome 10.0 IDH1 IDH2
29 drug-induced mental disorder 10.0 IDH1 IDH2
30 drug psychosis 10.0 IDH1 IDH2
31 undifferentiated pleomorphic sarcoma 10.0 IDH1 IDH2
32 2-hydroxyglutaric aciduria 10.0 IDH1 IDH2
33 d-2-hydroxyglutaric aciduria 1 10.0 IDH1 IDH2
34 bile duct adenocarcinoma 10.0 IDH1 IDH2
35 brain stem glioma 9.9 IDH1 IDH2
36 supratentorial cancer 9.9 IDH1 IDH2
37 cerebrum cancer 9.9 IDH1 IDH2
38 central nervous system cancer 9.9 IDH1 IDH2
39 intrahepatic cholangiocarcinoma 9.9 IDH1 IDH2
40 cholangiocarcinoma 9.9 IDH1 IDH2
41 camurati-engelmann disease 9.9
42 fibrodysplasia ossificans progressiva 9.9
43 fibromuscular dysplasia 9.9
44 osteopoikilosis 9.9
45 patulous eustachian tube 9.9
46 mucocele of salivary gland 9.9
47 paronychia 9.9
48 coccidioidomycosis 9.9
49 giant cell reparative granuloma 9.9
50 relapsing polychondritis 9.9

Graphical network of the top 20 diseases related to Enchondroma:



Diseases related to Enchondroma

Symptoms & Phenotypes for Enchondroma

UMLS symptoms related to Enchondroma:


pain

Drugs & Therapeutics for Enchondroma

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Low Grade Chondrosarcoma Versus Enchondroma Completed NCT02996747

Search NIH Clinical Center for Enchondroma

Genetic Tests for Enchondroma

Anatomical Context for Enchondroma

MalaCards organs/tissues related to Enchondroma:

41
Bone, Bone Marrow, Breast, Pituitary, Brain, Cerebellum, Myeloid

Publications for Enchondroma

Articles related to Enchondroma:

(show top 50) (show all 231)
# Title Authors Year
1
How to Diagnose Enchondroma, Bone Infarct, and Chondrosarcoma. ( 29724496 )
2018
2
Ultrasound manifestations of enchondroma protuberans: Two case reports. ( 29924025 )
2018
3
A case of enchondroma from Carolingian necropolis of St. Pere De Terrassa (Spain): An insight into the archaeological record. ( 29496221 )
2018
4
Enchondroma with Osteopoikilosis Coexisting Together -A Rare Clinical and Radiological Case Report. ( 29854696 )
2018
5
Enchondroma Protuberans of the Transverse Process of D8 Vertebra Extending to the 7th and 8th Ribs: A Rare Case Report. ( 30280082 )
2018
6
Enchondroma of Tibia as Potential False-positive Finding on 68Ga-DOTATOC PET/CT Scan. ( 30371598 )
2018
7
Curettage Using Soft-wire for Enchondroma in the Hand: A Technical Note. ( 29051884 )
2017
8
Another gouty tophus? The many faces of the enchondroma. ( 28242213 )
2017
9
Diagnostic value of MRI-based 3D texture analysis for tissue characterisation and discrimination of low-grade chondrosarcoma from enchondroma: a pilot study. ( 28884356 )
2017
10
Treatment of hand enchondroma with injectable calcium phosphate cement: a series of eight cases. ( 27942915 )
2017
11
Risk factors for local recurrence from atypical cartilaginous tumour and enchondroma of the long bones. ( 28501961 )
2017
12
Large enchondroma of the thoracic spine: a rare case report and review of the literature. ( 28407736 )
2017
13
Recurrence of Enchondroma in a Middle Finger after Curettage and Back-filling with Calcium Phosphate Bone Cement: a Case Report. ( 27492208 )
2016
14
Enchondroma Protuberans of the Ulna in a Pediatric Patient: A Case Report. ( 29252631 )
2016
15
Pathological Avulsion Fracture of the Flexor Digitorum Profundus after Enchondroma-Case Report. ( 27625544 )
2016
16
Enchondroma versus Chondrosarcoma in Long Bones of Appendicular Skeleton: Clinical and Radiological Criteria-A Follow-Up. ( 27034667 )
2016
17
Enchondroma in the distal phalanx of the finger: An observational study of 34 cases in a single institution. ( 27661057 )
2016
18
Predicting Fracture Risk for Enchondroma of the Hand. ( 27390564 )
2016
19
Radiologic follow-up of untreated enchondroma and atypical cartilaginous tumors in the long bones. ( 27696436 )
2016
20
Primary intra-osseous myoepithelioma of phalanx mimicking an enchondroma. ( 27524490 )
2016
21
Enchondroma of the Hand: Evaluation and Management. ( 27454024 )
2016
22
Use of MicroRNA biomarkers to distinguish enchondroma from low-grade chondrosarcoma. ( 27267924 )
2016
23
Expression of insulin-like growth factor II mRNA binding protein 3 (IMP3) in enchondroma and chondrosarcoma. ( 26948096 )
2016
24
Recurrent Metacarpal Enchondroma Treated With Strut Allograft: 14-year Follow-up. ( 26186330 )
2015
25
Enchondroma of the scaphoid: a case report. ( 26327970 )
2015
26
Atypical Localization of Enchondroma in the Calcaneus. ( 25867903 )
2015
27
Enchondroma of the Skull Base in a Case of Ollier's Syndrome. ( 26351491 )
2015
28
Endoscopic curettage and bone grafting of the enchondroma of the proximal phalanx of the great toe. ( 25937415 )
2015
29
Enchondroma of the Distal Phalanx. ( 26129760 )
2015
30
Current management of hand enchondroma: a review. ( 25609298 )
2015
31
Enchondroma of the Foot. ( 26024560 )
2015
32
The surgical management of hand enchondroma without postcurettage void augmentation: authors' experience and a systematic review. ( 26330779 )
2015
33
A Rare Occurrence of Enchondroma in Neck of Femur in an Adult Female: A Case Report. ( 26816956 )
2015
34
Enchondroma of clivus: appearance on 18F-FDG PET-CT in contrast with MRI. ( 25489953 )
2015
35
Giant cell reparative granuloma of the hallux following enchondroma. ( 26985281 )
2015
36
Treatment of a fractured juxta-articular enchondroma of the middle phalanx with a Suzuki external fixator: a case report. ( 25706150 )
2015
37
Local review of treatment of hand enchondroma (artificial bone substitute versus autologous bone graft) in a tertiary referral centre: 13 years' experience. ( 25810024 )
2015
38
Osseous tumor of the hand: finger enchondroma. ( 25671055 )
2015
39
Enchondroma of the cervical spine in young woman: A rare case report. ( 26425170 )
2015
40
Arthroscopic treatment for femoral neck enchondroma: case report. ( 27011868 )
2015
41
Atypical Localization of Enchondroma in the Calcaneus. ( 26146974 )
2015
42
Avulsion of flexor digitorum profundus secondary to enchondroma of the distal phalanx. Case report and literature review. ( 26204827 )
2015
43
Identification of novel biomarker candidates for immunohistochemical diagnosis to distinguish low-grade chondrosarcoma from enchondroma. ( 25755173 )
2015
44
Can imaging criteria distinguish enchondroma from grade 1 chondrosarcoma? ( 26220916 )
2015
45
Phenolization and coralline hydroxyapatite grafting following meticulous curettage for the treatment of enchondroma of the hand. A case series of 82 patients with 5-year follow-up. ( 25767429 )
2015
46
A rare cartilaginous tumor in the phalangeal bone: enchondroma protuberans. ( 24901933 )
2014
47
Finger enchondroma treated with bone substituents - a case presentation. ( 25408730 )
2014
48
Regression of an enchondroma: a case report and proposed etiology. ( 25331356 )
2014
49
Insights into Enchondroma, Enchondromatosis and the risk of secondary Chondrosarcoma. Review of the literature with an emphasis on the clinical behaviour, radiology, malignant transformation and the follow up. ( 24645839 )
2014
50
Hypertrophic nonunion humerus mimicking an enchondroma. ( 25525539 )
2014

Variations for Enchondroma

Expression for Enchondroma

Search GEO for disease gene expression data for Enchondroma.

Pathways for Enchondroma

GO Terms for Enchondroma

Cellular components related to Enchondroma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peroxisome GO:0005777 8.62 IDH1 IDH2

Biological processes related to Enchondroma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 tricarboxylic acid cycle GO:0006099 9.32 IDH1 IDH2
2 2-oxoglutarate metabolic process GO:0006103 9.26 IDH1 IDH2
3 NADP metabolic process GO:0006739 9.16 IDH1 IDH2
4 isocitrate metabolic process GO:0006102 8.96 IDH1 IDH2
5 glyoxylate cycle GO:0006097 8.62 IDH1 IDH2

Molecular functions related to Enchondroma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 magnesium ion binding GO:0000287 9.32 IDH1 IDH2
2 NAD binding GO:0051287 9.26 IDH1 IDH2
3 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 9.16 IDH1 IDH2
4 isocitrate dehydrogenase (NADP+) activity GO:0004450 8.96 IDH1 IDH2
5 isocitrate dehydrogenase activity GO:0004448 8.62 IDH1 IDH2

Sources for Enchondroma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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