MCID: END030
MIFTS: 60

End Stage Renal Failure

Categories: Nephrological diseases

Aliases & Classifications for End Stage Renal Failure

MalaCards integrated aliases for End Stage Renal Failure:

Name: End Stage Renal Failure 39 12 15
End Stage Renal Disease 12 15
Chronic Kidney Disease Stage 5 74
Kidney Failure, Chronic 74

Classifications:



External Ids:

Disease Ontology 12 DOID:783

Summaries for End Stage Renal Failure

MalaCards based summary : End Stage Renal Failure, also known as end stage renal disease, is related to frasier syndrome and nephrotic syndrome, type 1, and has symptoms including cloudy (hemodialysis) (peritoneal) dialysis effluent An important gene associated with End Stage Renal Failure is UMOD (Uromodulin), and among its related pathways/superpathways are Pathways in cancer and Selenium Micronutrient Network. The drugs Capsaicin and Simvastatin have been mentioned in the context of this disorder. Affiliated tissues include kidney, heart and bone, and related phenotypes are homeostasis/metabolism and cardiovascular system

Wikipedia : 77 Chronic kidney disease (CKD) is a type of kidney disease in which there is gradual loss of kidney... more...

Related Diseases for End Stage Renal Failure

Diseases related to End Stage Renal Failure via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 720)
# Related Disease Score Top Affiliating Genes
1 frasier syndrome 32.9 NPHS1 NPHS2 WT1
2 nephrotic syndrome, type 1 32.8 NPHS1 NPHS2 WT1
3 nephrotic syndrome, type 6 32.4 NPHS1 NPHS2 WT1
4 anuria 31.6 ACE AGT AGTR1 ALB
5 critical limb ischemia 31.1 IL6 TNF
6 limb ischemia 30.8 ACE IL6 TNF
7 periodontitis 30.7 CRP IL6 TNF
8 acute cystitis 30.7 ALB CRP IL6
9 pericarditis 30.6 CRP IL6 TNF
10 atherosclerosis susceptibility 30.6 CRP IL6 TNF
11 deficiency anemia 30.6 ALB CRP EPO IL6
12 calciphylaxis 30.5 ALB EPO PTH
13 pulmonary edema 30.5 ACE CRP TNF
14 sleep apnea 30.5 ACE CRP IL6 TNF
15 urinary tract obstruction 30.5 ALB TGFB1 UMOD
16 peritonitis 30.5 ALB CRP IL6 TNF
17 nephrotic syndrome 30.5 ALB COQ6 NPHS1 NPHS2 WT1
18 peripheral vascular disease 30.5 ACE ALB CRP IL6
19 uremia 30.4 ALB CRP EPO PTH
20 vesicoureteral reflux 1 30.4 AGT AGTR1 UMOD
21 denys-drash syndrome 30.4 NPHS1 NPHS2 WT1
22 systemic scleroderma 30.3 ACE CRP TGFB1
23 coronary stenosis 30.3 ACE ALB CRP IL6
24 malignant hypertension 30.3 ACE AGT AGTR1
25 glomerulonephritis 30.3 ALB COL4A5 NPHS1 NPHS2 TGFB1
26 microvascular complications of diabetes 3 30.2 ACE AGT AGTR1 ALB NPHS1
27 thrombocytosis 30.2 CRP EPO IL6
28 peripheral nervous system disease 30.2 ALB IL6 TNF
29 endocarditis 30.2 ALB CRP IL6 TNF
30 poems syndrome 30.2 EPO IL6 TNF
31 acquired immunodeficiency syndrome 30.2 ALB EPO IL6 TNF
32 myeloma, multiple 30.1 ALB CRP EPO FN1 IL6 TNF
33 tuberculous peritonitis 30.1 ALB CRP TNF
34 acute kidney tubular necrosis 30.1 ALB CST3 UMOD
35 infective endocarditis 30.1 CRP IL6 TNF
36 angina pectoris 30.1 ACE CRP IL6
37 leptospirosis 30.1 CRP IL6 TNF
38 pyelonephritis 30.1 ACE ALB CRP IL6 TNF UMOD
39 interstitial nephritis 30.1 ACE AGT ALB CRP UMOD
40 carotid stenosis 30.0 ACE CRP TNF
41 spinal cord injury 30.0 IL6 TGFB1 TNF
42 brucellosis 30.0 CRP IL6 TNF
43 temporal arteritis 30.0 CRP IL6 TNF
44 hepatic encephalopathy 30.0 ALB IL6 TNF
45 aortic valve disease 2 30.0 ACE AGT CRP
46 cystitis 30.0 CRP IL6 TNF UMOD
47 autosomal dominant polycystic kidney disease 29.9 ACE AGT ALB CST3 PKD1
48 diffuse mesangial sclerosis 29.9 NPHS1 NPHS2 TGFB1 WT1
49 obstructive nephropathy 29.9 ACE AGT ALB TGFB1
50 vascular disease 29.9 ACE ALB CRP CST3 IL6 TNF

Graphical network of the top 20 diseases related to End Stage Renal Failure:



Diseases related to End Stage Renal Failure

Symptoms & Phenotypes for End Stage Renal Failure

UMLS symptoms related to End Stage Renal Failure:


cloudy (hemodialysis) (peritoneal) dialysis effluent

MGI Mouse Phenotypes related to End Stage Renal Failure:

47 (show all 15)
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.46 ACE AGT AGTR1 ALB COL4A5 COQ6
2 cardiovascular system MP:0005385 10.44 ACE AGT AGTR1 COL4A5 CRP CST3
3 growth/size/body region MP:0005378 10.34 ACE AGT AGTR1 COQ6 FN1 IL6
4 mortality/aging MP:0010768 10.32 ACE AGT AGTR1 ALB COL4A5 COQ6
5 immune system MP:0005387 10.31 ACE AGT AGTR1 COL4A5 CRP EPO
6 cellular MP:0005384 10.26 ALB EPO FN1 IL6 MYH9 PKD1
7 hematopoietic system MP:0005397 10.26 ACE AGTR1 COL4A5 EPO FN1 IL6
8 adipose tissue MP:0005375 10.2 ACE AGT AGTR1 COL4A5 IL6 PKD1
9 embryo MP:0005380 10.11 COQ6 EPO FN1 MYH9 PKD1 TGFB1
10 liver/biliary system MP:0005370 10.1 ACE AGT ALB EPO FN1 IL6
11 muscle MP:0005369 10.02 AGT ALB CST3 EPO FN1 IL6
12 neoplasm MP:0002006 9.91 ACE ALB CST3 FN1 IL6 PKD1
13 nervous system MP:0003631 9.9 AGT AGTR1 COQ6 CST3 FN1 IL6
14 renal/urinary system MP:0005367 9.77 ACE AGT AGTR1 ALB COL4A5 IL6
15 reproductive system MP:0005389 9.28 ACE AGT CST3 FN1 IL6 PKD1

Drugs & Therapeutics for End Stage Renal Failure

Drugs for End Stage Renal Failure (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 814)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Capsaicin Approved Phase 4 404-86-4 1548943
2
Simvastatin Approved Phase 4,Not Applicable 79902-63-9 54454
3
Ribavirin Approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 36791-04-5 37542
4
Peginterferon alfa-2b Approved Phase 4,Phase 1,Not Applicable 215647-85-1, 99210-65-8
5
Nitric Oxide Approved Phase 4,Phase 1,Phase 2,Not Applicable 10102-43-9 145068
6
Digoxin Approved Phase 4 20830-75-5 2724385 30322
7
Acetylcysteine Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 616-91-1 12035
8
Clopidogrel Approved Phase 4,Phase 3,Not Applicable 120202-66-6, 113665-84-2 60606
9
Ticagrelor Approved Phase 4,Phase 3,Phase 1,Phase 2 274693-27-5 9871419
10
Angiotensin II Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 11128-99-7, 68521-88-0, 4474-91-3 172198
11
Losartan Approved Phase 4,Phase 3,Not Applicable 114798-26-4 3961
12
Olmesartan Approved, Investigational Phase 4,Phase 3,Not Applicable 144689-24-7, 144689-63-4 158781 130881
13
Candesartan cilexetil Approved Phase 4,Phase 3,Phase 2,Not Applicable 145040-37-5 2540
14
Telmisartan Approved, Investigational Phase 4,Phase 3,Not Applicable 144701-48-4 65999
15
Pentoxifylline Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 6493-05-6 4740
16
Valsartan Approved, Investigational Phase 4,Phase 3,Phase 2 137862-53-4 60846
17
Irbesartan Approved, Investigational Phase 4,Phase 3,Phase 2 138402-11-6 3749
18
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 3 2078-54-8 4943
19
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 3 113775-47-6 5311068 68602
20
Tacrolimus Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 104987-11-3 6473866 445643 439492
21
Benzocaine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 1994-09-7, 94-09-7 2337
22
alemtuzumab Approved, Investigational Phase 4,Phase 1,Phase 2 216503-57-0
23
tannic acid Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 1401-55-4
24
Sodium Citrate Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 68-04-2
25
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 9005-49-6 46507594 772
26
Dalteparin Approved Phase 4,Phase 2,Phase 3,Not Applicable 9005-49-6
27
Nadroparin Approved, Investigational Phase 4
28
Ursodeoxycholic acid Approved, Investigational Phase 4 128-13-2 31401
29
Furosemide Approved, Vet_approved Phase 4,Phase 3,Phase 1,Not Applicable 54-31-9 3440
30
Oxycodone Approved, Illicit, Investigational Phase 4 76-42-6 5284603
31
Spironolactone Approved Phase 4,Phase 3,Phase 2,Not Applicable 1952-01-7, 52-01-7 5833
32
Lidocaine Approved, Vet_approved Phase 4,Not Applicable 137-58-6 3676
33
Bupivacaine Approved, Investigational Phase 4,Phase 3,Not Applicable 38396-39-3, 2180-92-9 2474
34
Pregabalin Approved, Illicit, Investigational Phase 4 148553-50-8 5486971
35
Alendronate Approved Phase 4,Not Applicable 66376-36-1, 121268-17-5 2088
36
Hydrochlorothiazide Approved, Vet_approved Phase 4,Phase 3,Not Applicable 58-93-5 3639
37
Pioglitazone Approved, Investigational Phase 4,Phase 2,Not Applicable 111025-46-8 4829
38
Acarbose Approved, Investigational Phase 4 56180-94-0 441184
39
Atorvastatin Approved Phase 4,Phase 1,Phase 2,Not Applicable 134523-00-5 60823
40
Ezetimibe Approved Phase 4 163222-33-1 150311
41
Fosinopril Approved Phase 4,Phase 3,Not Applicable 98048-97-6 55891
42
Amlodipine Approved Phase 4,Phase 3,Phase 2,Not Applicable 88150-42-9 2162
43
Darbepoetin alfa Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 209810-58-2, 11096-26-7
44
Everolimus Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 159351-69-6 70789204 6442177
45
Sirolimus Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 53123-88-9 46835353 5284616 6436030
46
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 22916-47-8 4189
47
Cinacalcet Approved Phase 4,Phase 3,Phase 2,Not Applicable 226256-56-0 156419
48
Colchicine Approved Phase 4,Phase 2 64-86-8 2833 6167
49
Mycophenolic acid Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 24280-93-1 446541
50 Taurolidine Approved, Investigational Phase 4,Phase 3 19388-87-5

Interventional clinical trials:

(show top 50) (show all 2164)
# Name Status NCT ID Phase Drugs
1 Qutenza for Critical Ischaemia in End Stage Renal Failure Unknown status NCT01704339 Phase 4 QUTENZA
2 Inspiratory Muscle Training in Patients With End Stage Renal Failure Unknown status NCT01347775 Phase 4
3 Simvastatin Effect on End Stage Renal Failure Patients Treated by Peritoneal Dialysis Unknown status NCT00291863 Phase 4 Simvastatin
4 Effect of Sodium Rinsing Fluid on Blood Pressure and Interdialytic Weight Change in Hemodialysis Patients Unknown status NCT02590081 Phase 4 Dextrose 5%;normal saline
5 A Pilot Study to Treat Patients With Chronic Hepatitis C Virus (HCV) Genotype 1 and End-Stage Renal Disease (ESRD) Unknown status NCT01731301 Phase 4 Ribavirin;Peginterferon;Boceprevir
6 Far Infrared Therapy on AV Fistula Flow, Endothelial Function and Echocardiography in ESRD Patients Unknown status NCT01138254 Phase 4
7 Marinobufagenin as a Target for DIGIBIND in Hypertensive Patients With End-stage Renal Disease Unknown status NCT00852787 Phase 4 Digoxin immune fab;Placebo
8 Effect of Hydration With Sodium Bicarbonate for Long-Term Clinical Outcomes in Patients With Chronic Kidney Disease Undergoing an Emergent Coronary Procedure Unknown status NCT00716001 Phase 4 N-acetylcysteine
9 Platelet Resistance With Ticagrelor or Standard-Dose Clopidogrel Among CKD and ACS Patients Unknown status NCT02459288 Phase 4 Clopidogrel first;Ticagrelor first
10 NAC in Preventing CIN in CRF Patients Who Need Enhanced CT Scan in ED Unknown status NCT00501475 Phase 4 NAC Bicarbonate
11 Renoprotection by Pentoxifylline and Angiotensin Receptor Blocker in Chronic Kidney Disease (CKD) Unknown status NCT01377285 Phase 4 ARB;Pentoxifylline;Placebo (for Pentoxifylline)
12 Dexmedetomidine and Propofol As Sole Sedative Agent for Patients Undergoing Arteriovenous Fistula Surgery Unknown status NCT02447796 Phase 4 Propofol;Dexmedetomidine
13 Effect of Laparoscopic Sleeve Gastrectomy in the Morbidly Obese, Kidney Transplant Candidate Unknown status NCT01913392 Phase 4
14 Effects of On-Line Hemodiafiltration(HDF) on Vascular Health in Chronic Hemodialysis Patients Unknown status NCT00532597 Phase 4
15 Standard Versus Prolonged-release Tacrolimus Monotherapy After Alemtuzumab Induction in Kidney Transplantation Unknown status NCT00807144 Phase 4 Tacrolimus (Kidney transplant maintenance immunosuppression);Kidney transplant maintenance immunosuppression
16 A Study of Ferric Citrate to Improve Inflammation and Lipid Levels Unknown status NCT02661295 Phase 4 Ferric Citrate
17 LMWH Infusion as Anticoagulation for Home HD Unknown status NCT02957877 Phase 4 Nadroparin;Unfractionated heparin
18 Effect of Ursodeoxycholic Acid on Peritoneal Function in Patients on Peritoneal Dialysis Unknown status NCT02338635 Phase 4 Ursodeoxycholic Acid
19 The Use of Furosemide in Patients on Dialysis Unknown status NCT01815892 Phase 4 Withdrawal of furosemide;furosemide administration
20 Body Composition Monitor in Hemodialysis Patients Unknown status NCT01103167 Phase 4
21 Effect of Different Hemodialysis Modality on Adiponectin,Vascular Function and Clinical Prognosis Unknown status NCT00155363 Phase 4
22 Effects of an Exercise Program in Patients With Hypertensive Chronic Kidney Disease Unknown status NCT01155128 Phase 4
23 Opioids in Chronic Kidney Disease Patients Undergoing Hemodialysis Unknown status NCT02452437 Phase 4 Oxycodone
24 Hypervolemia in ESRD Patients in Zonguldak (Prospective Study) Unknown status NCT01468363 Phase 4
25 Cardiovascular Protective Effect of Spironolactone in Hemodialysis Unknown status NCT00277693 Phase 4 Spironolactone (drug)
26 The Canadian Prevention of Renal and Cardiovascular Endpoints Trial Unknown status NCT00231803 Phase 4
27 Intravenous Paricalcitol in Chronic Hemodialysis Patients Unknown status NCT03023748 Phase 4 Intravenous Paricalcitol
28 Anti-Oxidant Effect on Peritoneal Membrane in Peritoneal Dialysis (PD) Patients Unknown status NCT01111422 Phase 4 N-acetylcysteine
29 RAAS Inhibitor Drugs in Dialysis Patients Unknown status NCT01635387 Phase 4 aliskiren
30 2% Lidocaine Plus 0.5% Bupivacaine Versus 0.5% Bupivacaine in Brachial Block for Creation of Arteriovenous (AV) Fistula Unknown status NCT00993746 Phase 4 Bupivacaine plus lidocaine;Bupivacaine 30 ml
31 Safety and Effect of Elbasvir/Grazoprevir Combination Therapy in Hemodialysis Patients With Chronic Hepatitis C Unknown status NCT03022006 Phase 4 elbasvir, grazoprevir
32 Effects of Cholecalciferol on Osteoprotegerin Levels in Patients on Peritoneal Dialysis Unknown status NCT02598635 Phase 4 Cholecalciferol;Placebo
33 The Effect and Safety of the Seasonal Trivalent Influenza Vaccine in Chronic Kidney Disease Patients Not on Dialysis Unknown status NCT02105519 Phase 4
34 Far Infrared Therapy on Peripheral Artery Disease in Hemodialysis Patients Unknown status NCT01095549 Phase 4
35 Efficacy of Pregabalin in the Management of Chronic Uremic Pruritus Unknown status NCT01073501 Phase 4 Pregabalin;Placebo
36 Clinical Impact of Bacteriuria on Chronic Inflammation in Asymptomatic Hemodialysis Patients Unknown status NCT01570556 Phase 4
37 Alendronate for Vascular Calcification in Peritoneal Dialysis Patients? Unknown status NCT00299572 Phase 4 alendronate (Fosamax)
38 Clinical Trial Technology Development for the Validation of Surrogate Prognostic Markers in Patients With Diabetic Nephropathy Unknown status NCT01673204 Phase 4 Calcitriol;Placebo
39 Effect of Intravenous Acetadote on Incidence of Contrast Induced Nephropathy Unknown status NCT00939913 Phase 4 intravenous NAC;Placebo
40 Clinical Trial to Compare Effectiveness of Diuretics in Hemodialysis Patients With Residual Renal Function Unknown status NCT01977430 Phase 4 Hydrochlorothiazide and furosemide
41 Thiazolidinedione (TZD) on the Diabetic Retinopathy and Nephropathy Unknown status NCT01175486 Phase 4 Actos (Pioglitazone);Acarbose
42 Oxidative Stress Lowering Effect of Simvastatin and Atorvastatin. Unknown status NCT00404599 Phase 4 atrorvastatin 10mg;simvastatin 40mg
43 The Effects of Acetylcysteine on Alleviating Damage of Oxidative Stress in Hemodialysis Patients Unknown status NCT00247507 Phase 4 acetylcysteine
44 Ezetimibe/Simvastatin Combination in Proteinuric Nephropathy Unknown status NCT00861731 Phase 4 simvastatin;EZE/simvastatin;EZE/simvastatin
45 Benidipine and Hydrochlorothiazide in Fosinopril Treated Chronic Kidney Disease Patients With Hypertension Unknown status NCT02646397 Phase 4 Fosinopril;Benidipine;Hydrochlorothiazide
46 Revascularization of Renal Artery Stenosis Versus Medical Therapy for the Treatment of Ischemic Nephropathy Unknown status NCT01023373 Phase 4 Medical treatment
47 Study Response of 13-valent Conjugate Pneumococcal Vaccine in Patients With End Stage Renal Disease Completed NCT01974817 Phase 4
48 Effect of Dialysis on the Pharmacokinetics of Telavancin in Patients With Chronic Kidney Disease Stage 5 Completed NCT02392208 Phase 4 Telavancin
49 Influence of Amlodipine on the Mortality of Patients With End-Stage Renal Failure Completed NCT00124969 Phase 4 Amlodipine;Placebo
50 Parathyroidectomy in Endstage Renal Disease Completed NCT00745719 Phase 4

Search NIH Clinical Center for End Stage Renal Failure

Inferred drug relations via UMLS 74 / NDF-RT 52 :


Genetic Tests for End Stage Renal Failure

Anatomical Context for End Stage Renal Failure

MalaCards organs/tissues related to End Stage Renal Failure:

42
Kidney, Heart, Bone, Liver, Endothelial, Testes, T Cells

Publications for End Stage Renal Failure

Articles related to End Stage Renal Failure:

(show top 50) (show all 3952)
# Title Authors Year
1
Efficacy and Safety of Ticagrelor Compared with Clopidogrel in Patients with End-Stage Renal Disease with Acute Myocardial Infarction. ( 30746615 )
2019
2
T-cell aging in end-stage renal disease: an evolving story with CMV. ( 30903371 )
2019
3
Cognitive impairment in patients with end-stage renal disease: Accelerated brain aging? ( 30744935 )
2019
4
Aging and End Stage Renal Disease Cause A Decrease in Absolute Circulating Lymphocyte Counts with A Shift to A Memory Profile and Diverge in Treg Population. ( 30705767 )
2019
5
Rapid progression to end-stage renal disease in a young female with mixed immunopathological features of lupus and ANCA-associated vasculitis. ( 30968562 )
2019
6
Patients with end-stage renal disease have poor outcomes after endovascular abdominal aortic aneurysm repair. ( 29945838 )
2019
7
Effects of Arteriovenous Fistula on Blood Pressure in Patients With End-Stage Renal Disease: A Systematic Meta-Analysis. ( 30764686 )
2019
8
Comparison of incidence of acute kidney injury, chronic kidney disease and end-stage renal disease between atrial fibrillation and atrial flutter: real-world evidences from a propensity score-matched national cohort analysis. ( 31073825 )
2019
9
Use of Oral Anticoagulation in Patients With Atrial Fibrillation and End-stage Renal Disease: What Is Needed Nowadays? Response. ( 30173947 )
2019
10
Use of Oral Anticoagulation for Patients With Atrial Fibrillation and End-stage Renal Disease: What Is Needed Nowadays? ( 30126663 )
2019
11
Calcific olecranon bursitis in end-stage renal disease. ( 30421305 )
2019
12
A persistent penile ulcer in end stage renal disease: It is not always calciphylaxis. ( 31050098 )
2019
13
Increased risk of central serous chorioretinopathy following end-stage renal disease: A nationwide population-based study. ( 30882685 )
2019
14
End-stage renal disease secondary to anti-glomerular basement membrane disease in a child with common variable immunodeficiency. ( 30838168 )
2019
15
Risk of dementia in patients with end-stage renal disease under maintenance dialysis-a nationwide population-based study with consideration of competing risk of mortality. ( 30967155 )
2019
16
An Integrative Review of Depression in Patients Receiving Hemodialysis for End-stage Renal Disease and the Relevance to Patients With Wounds. ( 30724747 )
2019
17
Peritoneal Dialysis as an Option for Unplanned Dialysis Initiation in Patients with End-Stage Renal Disease and Diabetes Mellitus. ( 30223256 )
2019
18
End-stage renal disease in a Down syndrome patient caused by delayed diagnosis of nonneurogenic bladder: A case report. ( 30985687 )
2019
19
Childhood kidney disease is associated with increased risk of end-stage renal failure in adulthood. ( 29853551 )
2019
20
The influence of hypothyroidism and substitution treatment on thyroid hormone conversion ratios and rT3 concentration in patients with end-stage renal failure. ( 30480752 )
2019
21
Applying Enhanced Recovery After Bariatric Surgery (ERABS) Protocol for Morbidly Obese Patients With End-Stage Renal Failure. ( 30617911 )
2019
22
Simplified end stage renal failure risk prediction model for the low-risk general population with chronic kidney disease. ( 30794622 )
2019
23
A Cost Analysis of Haemodialysis and Peritoneal Dialysis for the Management of End-Stage Renal Failure At an Academic Hospital in Pretoria, South Africa. ( 30868410 )
2019
24
End-stage renal failure is associated with impaired coronary microvascular function. ( 30883431 )
2019
25
The experiences of suffering of end-stage renal failure patients in Malaysia: a thematic analysis. ( 30943744 )
2019
26
Association of Staphylococcus nasal colonization and HIV in end-stage renal failure patients undergoing peritoneal dialysis. ( 30991864 )
2019
27
Treating TNF Receptor Associated Periodic Fever Syndrome in End-Stage Renal Failure. ( 31007959 )
2019
28
The Effect of Renal Transplantation in End-Stage Renal Failure Patients Undergoing Total Hip Replacement. ( 31080282 )
2019
29
Refractory ascites as a presenting feature of extramedullary plasmacytoma in an end-stage renal disease patient with HIV infection. ( 30838169 )
2019
30
A 44-year-old female with familial Mediterranean fever, cardiomyopathy and end stage renal disease. ( 30821026 )
2019
31
Commentary to "A 44-year-old female with familial Mediterranean fever, cardiomyopathy and end stage renal disease" by Magaki et al. ( 30710407 )
2019
32
Successful Use of Cangrelor and Heparin for Cardiopulmonary Bypass in a Patient With Heparin-Induced Thrombocytopenia and End-Stage Renal Disease: A Case Report. ( 30688681 )
2019
33
Sero Conversion of Viral Hepatitis among End Stage Renal Disease Patients on Hemodialysis in Kashmir: Results of a Prospective Study. ( 30894917 )
2019
34
Pathophysiology and Treatment of Hepatitis B and C Infections in Patients With End-Stage Renal Disease. ( 30876616 )
2019
35
Successful Treatment With Direct-Acting Antiviral Agents of Hepatitis C in Patients With End-Stage Renal Disease and Kidney Transplant Recipients. ( 30719954 )
2019
36
Mortality risk after herpes zoster infection in end-stage renal disease patients. ( 30746135 )
2019
37
Changing landscape of the treatment of hyperparathyroidism related to end-stage renal disease-can we turn the clock backward? ( 30266441 )
2019
38
A systematic review of the economic evaluations of non-calcium-containing phosphate binders, sevelamer and Lanthanum, in end-stage renal disease patients with hyperphosphatemia. ( 30664365 )
2019
39
Severe Hypoglycemia as a Predictor of End-Stage Renal Disease in Type 2 Diabetes: A National Cohort Study. ( 30813549 )
2019
40
Economic Issues of Chronic Kidney Disease and End-Stage Renal Disease. ( 30991413 )
2019
41
Elevated Serum Anion Gap in Adults with Moderate Chronic Kidney Disease Increases Risk for Progression to End Stage Renal Disease. ( 30908932 )
2019
42
Neutrophil-to-lymphocyte ratio and incident end-stage renal disease in Chinese patients with chronic kidney disease: results from the Chinese Cohort Study of Chronic Kidney Disease (C-STRIDE). ( 30876475 )
2019
43
Clostridioides difficile Infection in Chronic Kidney Disease/End-Stage Renal Disease. ( 30876614 )
2019
44
Antibiotic Dosing in Chronic Kidney Disease and End-Stage Renal Disease: A Focus on Contemporary Challenges. ( 30876619 )
2019
45
Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis. ( 30888644 )
2019
46
Impaired Left Ventricular Global Longitudinal Strain among Patients with Chronic Kidney Disease and End-Stage Renal Disease and Renal Transplant Recipients. ( 30485849 )
2019
47
Effects of chronic kidney disease stage 4, end-stage renal disease, or dialysis on the plasma concentrations of ombitasvir, paritaprevir, ritonavir, and dasabuvir in patients with chronic HCV infection: pharmacokinetic analysis of the phase 3 RUBY-I and RUBY-II trials. ( 30291369 )
2019
48
Changes in sensory proteins in the bladder urothelium of patients with chronic kidney disease and end-stage renal disease. ( 30198096 )
2019
49
Cause of kidney disease and cardiovascular events in a national cohort of US patients with end-stage renal disease on dialysis: a retrospective analysis. ( 30085056 )
2019
50
Thoracic Liposarcoma In An End Stage Renal Disease Patient. ( 31094134 )
2019

Variations for End Stage Renal Failure

Expression for End Stage Renal Failure

Search GEO for disease gene expression data for End Stage Renal Failure.

Pathways for End Stage Renal Failure

Pathways related to End Stage Renal Failure according to GeneCards Suite gene sharing:

(show all 24)
# Super pathways Score Top Affiliating Genes
1 12.63 AGTR1 COL4A5 EPO FN1 IL6 TGFB1
2
Show member pathways
12.22 ALB CRP IL6 TNF
3
Show member pathways
12.1 ACE IL6 TGFB1 TNF
4 11.9 ALB IL6 TGFB1 WT1
5 11.88 AGT IL6 TGFB1 TNF
6 11.76 FN1 IL6 TGFB1 TNF
7 11.74 IL6 TGFB1 TNF
8 11.64 IL6 TGFB1 TNF
9 11.64 COL4A5 FN1 IL6 TGFB1 TNF
10 11.62 IL6 TGFB1 TNF
11 11.59 ACE AGT AGTR1
12 11.54 IL6 TGFB1 TNF
13 11.43 AGTR1 COL4A5 FN1 IL6 TGFB1 TNF
14 11.41 COL4A5 FN1 TGFB1
15 11.4 IL6 TGFB1 TNF
16 11.38 FN1 IL6 TNF
17 11.37 EPO IL6 TGFB1
18 11.32 IL6 PTH TNF
19 11.01 IL6 TGFB1 TNF
20 10.97 COL4A5 MYH9 NPHS1 NPHS2 TGFB1 WT1
21 10.91 COL4A5 FN1 IL6 TGFB1 TNF
22 10.82 FN1 PKD1 TGFB1
23 10.76 TGFB1 TNF
24 10.74 CRP FN1 IL6 TNF

GO Terms for End Stage Renal Failure

Cellular components related to End Stage Renal Failure according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.85 ACE AGT ALB CST3 FN1 MYH9
2 extracellular region GO:0005576 9.77 ACE AGT ALB COL4A5 CRP CST3
3 endoplasmic reticulum lumen GO:0005788 9.65 ALB COL4A5 CST3 FN1 IL6
4 blood microparticle GO:0072562 9.62 AGT ALB FN1 TGFB1
5 platelet alpha granule lumen GO:0031093 9.54 ALB FN1 TGFB1
6 slit diaphragm GO:0036057 9.4 NPHS1 NPHS2
7 extracellular space GO:0005615 9.4 ACE AGT ALB COL4A5 CRP CST3

Biological processes related to End Stage Renal Failure according to GeneCards Suite gene sharing:

(show all 37)
# Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 9.94 ALB CST3 FN1 IL6
2 leukocyte migration GO:0050900 9.93 FN1 MYH9 TGFB1 TNF
3 regulation of signaling receptor activity GO:0010469 9.93 AGT EPO IL6 PTH TGFB1 TNF
4 regulation of cell proliferation GO:0042127 9.91 AGT AGTR1 TGFB1 TNF
5 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.89 AGT IL6 TGFB1 TNF
6 positive regulation of gene expression GO:0010628 9.88 CRP FN1 IL6 TGFB1 TNF WT1
7 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.84 AGT IL6 TGFB1
8 positive regulation of peptidyl-serine phosphorylation GO:0033138 9.84 IL6 TGFB1 TNF
9 positive regulation of inflammatory response GO:0050729 9.83 AGT AGTR1 TNF
10 positive regulation of fibroblast proliferation GO:0048146 9.79 AGT FN1 TGFB1
11 negative regulation of fat cell differentiation GO:0045599 9.78 IL6 TGFB1 TNF
12 excretion GO:0007588 9.71 NPHS1 NPHS2 UMOD
13 low-density lipoprotein particle remodeling GO:0034374 9.67 AGT AGTR1
14 regulation of blood vessel diameter GO:0097746 9.67 ACE AGTR1
15 glomerular basement membrane development GO:0032836 9.65 NPHS1 WT1
16 positive regulation of cholesterol esterification GO:0010873 9.65 AGT AGTR1
17 response to salt stress GO:0009651 9.65 EPO TNF
18 neutrophil mediated immunity GO:0002446 9.64 ACE IL6
19 positive regulation of NAD(P)H oxidase activity GO:0033864 9.63 AGT AGTR1
20 positive regulation of neuroinflammatory response GO:0150078 9.62 IL6 TNF
21 regulation of vasoconstriction GO:0019229 9.61 ACE AGT AGTR1
22 calcium-independent cell-matrix adhesion GO:0007161 9.58 FN1 PKD1
23 metanephric ascending thin limb development GO:0072218 9.58 PKD1 UMOD
24 negative regulation of extracellular matrix disassembly GO:0010716 9.57 CST3 TGFB1
25 regulation of renal sodium excretion GO:0035813 9.56 AGT AGTR1
26 renin-angiotensin regulation of aldosterone production GO:0002018 9.55 AGT AGTR1
27 kidney development GO:0001822 9.55 ACE AGT AGTR1 PKD1 WT1
28 positive regulation of cellular protein metabolic process GO:0032270 9.54 AGT AGTR1 TGFB1
29 positive regulation of mononuclear cell migration GO:0071677 9.52 TGFB1 TNF
30 regulation of blood vessel diameter by renin-angiotensin GO:0002034 9.51 AGT AGTR1
31 positive regulation of superoxide anion generation GO:0032930 9.5 AGT CRP TGFB1
32 mononuclear cell proliferation GO:0032943 9.49 ACE TGFB1
33 regulation of renal output by angiotensin GO:0002019 9.48 ACE AGT
34 negative regulation of lipid storage GO:0010888 9.43 CRP IL6 TNF
35 acute-phase response GO:0006953 9.26 CRP EPO FN1 IL6
36 regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 8.8 ACE AGT AGTR1
37 positive regulation of transcription, DNA-templated GO:0045893 10.08 AGT EPO IL6 TGFB1 TNF WT1

Molecular functions related to End Stage Renal Failure according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.26 EPO IL6 TGFB1 TNF
2 bradykinin receptor binding GO:0031711 8.62 ACE AGTR1

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