MCID: END030
MIFTS: 59

End Stage Renal Failure

Categories: Nephrological diseases

Aliases & Classifications for End Stage Renal Failure

MalaCards integrated aliases for End Stage Renal Failure:

Name: End Stage Renal Failure 38 12 15
End Stage Renal Disease 12 15
Chronic Kidney Disease Stage 5 73
Kidney Failure, Chronic 73

Classifications:



External Ids:

Disease Ontology 12 DOID:783

Summaries for End Stage Renal Failure

MalaCards based summary : End Stage Renal Failure, also known as end stage renal disease, is related to frasier syndrome and nephrotic syndrome, type 1, and has symptoms including cloudy (hemodialysis) (peritoneal) dialysis effluent An important gene associated with End Stage Renal Failure is UMOD (Uromodulin), and among its related pathways/superpathways are Pathways in cancer and Selenium Micronutrient Network. The drugs Capsaicin and Simvastatin have been mentioned in the context of this disorder. Affiliated tissues include kidney, bone and heart, and related phenotypes are homeostasis/metabolism and cardiovascular system

Wikipedia : 76 Chronic kidney disease (CKD) is a type of kidney disease in which there is gradual loss of kidney... more...

Related Diseases for End Stage Renal Failure

Diseases related to End Stage Renal Failure via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 633)
# Related Disease Score Top Affiliating Genes
1 frasier syndrome 32.6 NPHS1 NPHS2 WT1
2 nephrotic syndrome, type 1 32.5 NPHS1 NPHS2 WT1
3 nephrotic syndrome, type 6 32.2 NPHS1 NPHS2 WT1
4 anuria 31.6 ACE AGT AGTR1 ALB
5 secondary hyperparathyroidism of renal origin 30.6 ALB EPO PTH
6 limb ischemia 30.6 ACE IL6 TNF
7 periodontitis 30.4 CRP IL6 TNF
8 peritonitis 30.4 ALB CRP IL6 TNF
9 calciphylaxis 30.4 ALB EPO PTH
10 urinary tract obstruction 30.4 ALB TGFB1 UMOD
11 pericarditis 30.4 CRP IL6 TNF
12 acute cystitis 30.3 ALB CRP IL6
13 microvascular complications of diabetes 3 30.3 ACE AGT AGTR1 ALB NPHS1
14 glomerulonephritis 30.3 ALB COL4A5 NPHS1 NPHS2 TGFB1
15 myeloma, multiple 30.3 ALB CRP EPO IL6 TNF
16 nephrotic syndrome 30.2 ALB COQ6 NPHS1 NPHS2 WT1
17 coronary stenosis 30.2 ACE ALB CRP IL6
18 malignant hypertension 30.2 ACE AGT AGTR1
19 uremia 30.2 ALB CRP EPO PTH TF
20 pyelonephritis 30.1 ACE ALB CRP IL6 TNF UMOD
21 endocarditis 30.1 ALB CRP IL6 TNF
22 vascular disease 30.1 ACE ALB CRP CST3 IL6 TNF
23 thrombocytosis 30.1 CRP EPO IL6
24 peripheral nervous system disease 30.1 ALB IL6 TNF
25 interstitial nephritis 30.1 ACE AGT ALB CRP UMOD
26 sleep apnea 30.1 ACE CRP IL6 TNF
27 poems syndrome 30.0 EPO IL6 TNF
28 atherosclerosis susceptibility 30.0 CRP IL6 TNF
29 tuberculous peritonitis 30.0 ALB CRP TNF
30 infective endocarditis 30.0 CRP IL6 TNF
31 autosomal dominant polycystic kidney disease 30.0 ACE AGT ALB CST3 PKD1
32 spinal cord injury 30.0 IL6 TGFB1 TNF
33 acute kidney tubular necrosis 30.0 ALB CST3 UMOD
34 leptospirosis 30.0 CRP IL6 TNF
35 angina pectoris 29.9 ACE CRP IL6
36 analbuminemia 29.9 ALB CRP EPO NPHS1 TF
37 diabetes mellitus 29.9 ACE AGT AGTR1 ALB CRP EPO
38 obstructive nephropathy 29.9 ACE AGT ALB TGFB1
39 peripheral vascular disease 29.9 ACE ALB CRP IL6
40 pure red-cell aplasia 29.9 ALB EPO TF
41 carotid stenosis 29.9 ACE CRP TNF
42 temporal arteritis 29.9 CRP IL6 TNF
43 vesicoureteral reflux 1 29.9 AGT AGTR1 CRP UMOD
44 microvascular complications of diabetes 5 29.9 ACE AGTR1 ALB
45 cystitis 29.9 CRP IL6 TNF UMOD
46 systemic scleroderma 29.9 ACE CRP TGFB1
47 hepatic encephalopathy 29.9 ALB IL6 TNF
48 systemic lupus erythematosus 29.9 ACE ALB CRP IL6 TGFB1 TNF
49 acquired immunodeficiency syndrome 29.8 ALB EPO IL6 TNF
50 appendicitis 29.8 ALB CRP IL6 TNF

Graphical network of the top 20 diseases related to End Stage Renal Failure:



Diseases related to End Stage Renal Failure

Symptoms & Phenotypes for End Stage Renal Failure

UMLS symptoms related to End Stage Renal Failure:


cloudy (hemodialysis) (peritoneal) dialysis effluent

MGI Mouse Phenotypes related to End Stage Renal Failure:

46 (show all 11)
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.4 ACE AGT AGTR1 ALB COL4A5 COQ6
2 cardiovascular system MP:0005385 10.35 ACE AGT AGTR1 COL4A5 CRP CST3
3 growth/size/body region MP:0005378 10.3 ACE AGT AGTR1 COQ6 IL6 MYH9
4 hematopoietic system MP:0005397 10.21 ACE AGTR1 COL4A5 EPO IL6 MYH9
5 immune system MP:0005387 10.21 ACE AGT AGTR1 COL4A5 CRP EPO
6 mortality/aging MP:0010768 10.21 ACE AGT AGTR1 ALB COL4A5 COQ6
7 adipose tissue MP:0005375 10.15 ACE AGT AGTR1 COL4A5 IL6 PKD1
8 liver/biliary system MP:0005370 9.97 ACE AGT ALB EPO IL6 PKD1
9 muscle MP:0005369 9.81 AGT ALB CST3 EPO IL6 PKD1
10 neoplasm MP:0002006 9.56 ACE ALB CST3 IL6 PKD1 TGFB1
11 renal/urinary system MP:0005367 9.44 ACE AGT AGTR1 ALB COL4A5 IL6

Drugs & Therapeutics for End Stage Renal Failure

Drugs for End Stage Renal Failure (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 777)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Capsaicin Approved Phase 4 404-86-4 1548943
2
Simvastatin Approved Phase 4,Not Applicable 79902-63-9 54454
3
Peginterferon alfa-2b Approved Phase 4,Phase 1,Not Applicable 99210-65-8, 215647-85-1
4
Ribavirin Approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 36791-04-5 37542
5
Nitric Oxide Approved Phase 4,Phase 1,Phase 2,Not Applicable 10102-43-9 145068
6
Digoxin Approved Phase 4 20830-75-5 30322 2724385
7
Acetylcysteine Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 616-91-1 12035
8
Clopidogrel Approved Phase 4,Phase 3,Not Applicable 113665-84-2, 120202-66-6 60606
9
Ticlopidine Approved Phase 4,Phase 3 55142-85-3 5472
10
Ticagrelor Approved Phase 4,Phase 3,Phase 1,Phase 2 274693-27-5 9871419
11
Pentoxifylline Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 6493-05-6 4740
12
Irbesartan Approved, Investigational Phase 4,Phase 3,Phase 2 138402-11-6 3749
13
Telmisartan Approved, Investigational Phase 4,Phase 3,Not Applicable 144701-48-4 65999
14
Candesartan cilexetil Approved Phase 4,Phase 3,Phase 2,Not Applicable 145040-37-5 2540
15
Angiotensin II Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 11128-99-7, 68521-88-0, 4474-91-3 172198 65143
16
Valsartan Approved, Investigational Phase 4,Phase 3,Phase 2 137862-53-4 60846
17
Olmesartan Approved, Investigational Phase 4,Phase 3,Not Applicable 144689-63-4, 144689-24-7 158781 130881
18
Losartan Approved Phase 4,Phase 3,Not Applicable 114798-26-4 3961
19
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 3 2078-54-8 4943
20
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 3 113775-47-6 68602 5311068
21
Tacrolimus Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 104987-11-3 445643 439492
22
Benzocaine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 94-09-7, 1994-09-7 2337
23 tannic acid Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
24
alemtuzumab Approved, Investigational Phase 4,Phase 1,Phase 2 216503-57-0
25
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 9005-49-6 772 46507594
26
Dalteparin Approved Phase 4,Phase 2,Phase 3,Not Applicable 9005-49-6
27
Nadroparin Approved, Investigational Phase 4
28
Ursodeoxycholic acid Approved, Investigational Phase 4 128-13-2 31401
29
Furosemide Approved, Vet_approved Phase 4,Phase 3,Phase 1,Not Applicable 54-31-9 3440
30
Oxycodone Approved, Illicit, Investigational Phase 4 76-42-6 5284603
31
Spironolactone Approved Phase 4,Phase 3,Phase 2,Not Applicable 52-01-7, 1952-01-7 5833
32
Mupirocin Approved, Investigational, Vet_approved Phase 4 12650-69-0 446596
33
Chlorhexidine Approved, Vet_approved Phase 4,Not Applicable 55-56-1 2713 9552079
34
Lidocaine Approved, Vet_approved Phase 4,Not Applicable 137-58-6 3676
35
Bupivacaine Approved, Investigational Phase 4,Phase 3,Not Applicable 2180-92-9, 38396-39-3 2474
36
Pregabalin Approved, Illicit, Investigational Phase 4 148553-50-8 5486971
37
Alendronate Approved Phase 4,Not Applicable 66376-36-1, 121268-17-5 2088
38
Hydrochlorothiazide Approved, Vet_approved Phase 4,Phase 3,Not Applicable 58-93-5 3639
39
Acarbose Approved, Investigational Phase 4 56180-94-0 441184
40
Pioglitazone Approved, Investigational Phase 4,Phase 2,Not Applicable 111025-46-8 4829
41
Ezetimibe Approved Phase 4 163222-33-1 150311
42
Fosinopril Approved Phase 4,Phase 3,Not Applicable 98048-97-6 55891
43
Amlodipine Approved Phase 4,Phase 3,Phase 2,Not Applicable 88150-42-9 2162
44
Darbepoetin alfa Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 11096-26-7, 209810-58-2
45
Everolimus Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 159351-69-6 6442177
46
Sirolimus Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 53123-88-9 46835353 6436030 5284616
47
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 22916-47-8 4189
48
Colchicine Approved Phase 4,Phase 2 64-86-8 6167 2833
49
Mycophenolic acid Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 24280-93-1 446541
50 Taurolidine Approved, Investigational Phase 4,Phase 3 19388-87-5

Interventional clinical trials:

(show top 50) (show all 2080)
# Name Status NCT ID Phase Drugs
1 Qutenza for Critical Ischaemia in End Stage Renal Failure Unknown status NCT01704339 Phase 4 QUTENZA
2 Inspiratory Muscle Training in Patients With End Stage Renal Failure Unknown status NCT01347775 Phase 4
3 Simvastatin Effect on End Stage Renal Failure Patients Treated by Peritoneal Dialysis Unknown status NCT00291863 Phase 4 Simvastatin
4 Effect of Sodium Rinsing Fluid on Blood Pressure and Interdialytic Weight Change in Hemodialysis Patients Unknown status NCT02590081 Phase 4 Dextrose 5%;normal saline
5 A Pilot Study to Treat Patients With Chronic Hepatitis C Virus (HCV) Genotype 1 and End-Stage Renal Disease (ESRD) Unknown status NCT01731301 Phase 4 Ribavirin;Peginterferon;Boceprevir
6 Far Infrared Therapy on AV Fistula Flow, Endothelial Function and Echocardiography in ESRD Patients Unknown status NCT01138254 Phase 4
7 Marinobufagenin as a Target for DIGIBIND in Hypertensive Patients With End-stage Renal Disease Unknown status NCT00852787 Phase 4 Digoxin immune fab;Placebo
8 Effect of Hydration With Sodium Bicarbonate for Long-Term Clinical Outcomes in Patients With Chronic Kidney Disease Undergoing an Emergent Coronary Procedure Unknown status NCT00716001 Phase 4 N-acetylcysteine
9 Platelet Resistance With Ticagrelor or Standard-Dose Clopidogrel Among CKD and ACS Patients Unknown status NCT02459288 Phase 4 Clopidogrel first;Ticagrelor first
10 NAC in Preventing CIN in CRF Patients Who Need Enhanced CT Scan in ED Unknown status NCT00501475 Phase 4 NAC Bicarbonate
11 Renoprotection by Pentoxifylline and Angiotensin Receptor Blocker in Chronic Kidney Disease (CKD) Unknown status NCT01377285 Phase 4 ARB;Pentoxifylline;Placebo (for Pentoxifylline)
12 Dexmedetomidine and Propofol As Sole Sedative Agent for Patients Undergoing Arteriovenous Fistula Surgery Unknown status NCT02447796 Phase 4 Propofol;Dexmedetomidine
13 Effect of Laparoscopic Sleeve Gastrectomy in the Morbidly Obese, Kidney Transplant Candidate Unknown status NCT01913392 Phase 4
14 Effects of On-Line Hemodiafiltration(HDF) on Vascular Health in Chronic Hemodialysis Patients Unknown status NCT00532597 Phase 4
15 Standard Versus Prolonged-release Tacrolimus Monotherapy After Alemtuzumab Induction in Kidney Transplantation Unknown status NCT00807144 Phase 4 Tacrolimus (Kidney transplant maintenance immunosuppression);Kidney transplant maintenance immunosuppression
16 A Study of Ferric Citrate to Improve Inflammation and Lipid Levels Unknown status NCT02661295 Phase 4 Ferric Citrate
17 LMWH Infusion as Anticoagulation for Home HD Unknown status NCT02957877 Phase 4 Nadroparin;Unfractionated heparin
18 Effect of Ursodeoxycholic Acid on Peritoneal Function in Patients on Peritoneal Dialysis Unknown status NCT02338635 Phase 4 Ursodeoxycholic Acid
19 The Use of Furosemide in Patients on Dialysis Unknown status NCT01815892 Phase 4 Withdrawal of furosemide;furosemide administration
20 Body Composition Monitor in Hemodialysis Patients Unknown status NCT01103167 Phase 4
21 Effect of Different Hemodialysis Modality on Adiponectin,Vascular Function and Clinical Prognosis Unknown status NCT00155363 Phase 4
22 Effects of an Exercise Program in Patients With Hypertensive Chronic Kidney Disease Unknown status NCT01155128 Phase 4
23 Opioids in Chronic Kidney Disease Patients Undergoing Hemodialysis Unknown status NCT02452437 Phase 4 Oxycodone
24 Hypervolemia in ESRD Patients in Zonguldak (Prospective Study) Unknown status NCT01468363 Phase 4
25 Cardiovascular Protective Effect of Spironolactone in Hemodialysis Unknown status NCT00277693 Phase 4 Spironolactone (drug)
26 The Canadian Prevention of Renal and Cardiovascular Endpoints Trial Unknown status NCT00231803 Phase 4
27 Intravenous Paricalcitol in Chronic Hemodialysis Patients Unknown status NCT03023748 Phase 4 Intravenous Paricalcitol
28 Chlorhexidine Gluconate Versus Mupirocin Ointment in the Prevention of Peritoneal Dialysis-Related Infection Unknown status NCT02547103 Phase 4
29 Anti-Oxidant Effect on Peritoneal Membrane in Peritoneal Dialysis (PD) Patients Unknown status NCT01111422 Phase 4 N-acetylcysteine
30 RAAS Inhibitor Drugs in Dialysis Patients Unknown status NCT01635387 Phase 4 aliskiren
31 More Frequent Dialysis (>3 Treatments Per Week) Unknown status NCT00575497 Phase 4
32 2% Lidocaine Plus 0.5% Bupivacaine Versus 0.5% Bupivacaine in Brachial Block for Creation of Arteriovenous (AV) Fistula Unknown status NCT00993746 Phase 4 Bupivacaine plus lidocaine;Bupivacaine 30 ml
33 Effect of Arotinolol Hydrochloride on Cardiovascular Events in Hypertensive Haemodialysis Patients Unknown status NCT01351636 Phase 4 Arotinolol Hydrochloride;Non arotinolol group
34 The Effect and Safety of the Seasonal Trivalent Influenza Vaccine in Chronic Kidney Disease Patients Not on Dialysis Unknown status NCT02105519 Phase 4
35 Far Infrared Therapy on Peripheral Artery Disease in Hemodialysis Patients Unknown status NCT01095549 Phase 4
36 Efficacy of Pregabalin in the Management of Chronic Uremic Pruritus Unknown status NCT01073501 Phase 4 Pregabalin;Placebo
37 Clinical Impact of Bacteriuria on Chronic Inflammation in Asymptomatic Hemodialysis Patients Unknown status NCT01570556 Phase 4
38 Alendronate for Vascular Calcification in Peritoneal Dialysis Patients? Unknown status NCT00299572 Phase 4 alendronate (Fosamax)
39 Clinical Trial Technology Development for the Validation of Surrogate Prognostic Markers in Patients With Diabetic Nephropathy Unknown status NCT01673204 Phase 4 Calcitriol;Placebo
40 Effect of Intravenous Acetadote on Incidence of Contrast Induced Nephropathy Unknown status NCT00939913 Phase 4 intravenous NAC;Placebo
41 Clinical Trial to Compare Effectiveness of Diuretics in Hemodialysis Patients With Residual Renal Function Unknown status NCT01977430 Phase 4 Hydrochlorothiazide and furosemide
42 Thiazolidinedione (TZD) on the Diabetic Retinopathy and Nephropathy Unknown status NCT01175486 Phase 4 Actos (Pioglitazone);Acarbose
43 Oxidative Stress Lowering Effect of Simvastatin and Atorvastatin. Unknown status NCT00404599 Phase 4 atrorvastatin 10mg;simvastatin 40mg
44 The Effects of Acetylcysteine on Alleviating Damage of Oxidative Stress in Hemodialysis Patients Unknown status NCT00247507 Phase 4 acetylcysteine
45 Ezetimibe/Simvastatin Combination in Proteinuric Nephropathy Unknown status NCT00861731 Phase 4 simvastatin;EZE/simvastatin;EZE/simvastatin
46 Benidipine and Hydrochlorothiazide in Fosinopril Treated Chronic Kidney Disease Patients With Hypertension Unknown status NCT02646397 Phase 4 Fosinopril;Benidipine;Hydrochlorothiazide
47 Revascularization of Renal Artery Stenosis Versus Medical Therapy for the Treatment of Ischemic Nephropathy Unknown status NCT01023373 Phase 4 Medical treatment
48 Study Response of 13-valent Conjugate Pneumococcal Vaccine in Patients With End Stage Renal Disease Completed NCT01974817 Phase 4
49 Effect of Dialysis on the Pharmacokinetics of Telavancin in Patients With Chronic Kidney Disease Stage 5 Completed NCT02392208 Phase 4 Telavancin
50 Influence of Amlodipine on the Mortality of Patients With End-Stage Renal Failure Completed NCT00124969 Phase 4 Amlodipine;Placebo

Search NIH Clinical Center for End Stage Renal Failure

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Genetic Tests for End Stage Renal Failure

Anatomical Context for End Stage Renal Failure

MalaCards organs/tissues related to End Stage Renal Failure:

41
Kidney, Bone, Heart, Endothelial, Testes, Liver, T Cells

Publications for End Stage Renal Failure

Articles related to End Stage Renal Failure:

(show top 50) (show all 1884)
# Title Authors Year
1
Pulmonary hypertension in an adolescent with end-stage-renal disease-a diagnostic challenge: Questions. ( 29532234 )
2019
2
Pulmonary hypertension in an adolescent with end-stage-renal disease-a diagnostic challenge: Answers. ( 29532236 )
2019
3
Leveraging pragmatic clinical trial design to advance phosphate management in end-stage renal disease. ( 30480640 )
2019
4
High residual platelet reactivity after switching from clopidogrel to low-dose prasugrel in Japanese patients with end-stage renal disease on hemodialysis. ( 30055865 )
2019
5
Coconut atrium secondary to end-stage renal failure treated with long-term haemodialysis. ( 29688397 )
2018
6
Once-weekly hemodialysis combined with low-protein and low-salt dietary treatment as a favorable therapeutic modality for selected patients with end-stage renal failure: a prospective observational study in Japanese patients. ( 29954331 )
2018
7
'Known unknowns - examining the burden of neurocognitive impairment in the end-stage renal failure population'. ( 29345092 )
2018
8
A novel heterozygous GLI2 mutation in a patient with congenital urethral stricture and renal hypoplasia/dysplasia leading to end-stage renal failure. ( 29318530 )
2018
9
The cardiovascular risk factor profiles among end-stage renal failure patients treated with continuous ambulatory peritoneal dialysis and intermittent hemodialysis. ( 29456216 )
2018
10
End-Stage Renal Failure Is an Independent Risk Factor for 1-Year Mortality After Hip Fracture Surgery. ( 29707413 )
2018
11
Nutrient intake assessed with Diet History Questionnaire II, in relation to long-term calcium-phosphate control in hemodialysis patients with end-stage renal failure. ( 29521065 )
2018
12
A comprehensive characterization of aggravated aging-related changes in T lymphocytes and monocytes in end-stage renal disease: the iESRD study. ( 30455721 )
2018
13
Patient and Kidney Allograft Survival in Recipients With End-Stage Renal Disease From Amyloidosis. ( 28885498 )
2018
14
Prevalence of depression and anxiety in end-stage renal disease: A survey of patients undergoing hemodialysis. ( 30220369 )
2018
15
Predictive parameters of arteriovenous fistula maturation in patients with end-stage renal disease. ( 30254852 )
2018
16
Rheumatoid Arthritis and Mortality in End Stage Renal Disease. ( 30520821 )
2018
17
Use of Oral Anticoagulation in Patients With Atrial Fibrillation and End-stage Renal Disease: What Is Needed Nowadays? Response. ( 30173947 )
2018
18
Use of Oral Anticoagulation for Patients With Atrial Fibrillation and End-stage Renal Disease: What Is Needed Nowadays? ( 30126663 )
2018
19
Cardiovascular Autonomic Neuropathy and its Association with Cardiovascular and All-cause Mortality in Patients with End-stage Renal Disease. ( 30410849 )
2018
20
Erratum: Perrone RD, Mouksassi M-S, Romero K, et al. Total kidney volume is a prognostic biomarker of renal function decline and progression to end-stage renal disease in patients with autosomal dominant polycystic kidney disease. Kidney Int Rep. 2017;2:442-450. ( 29989052 )
2018
21
Calcific olecranon bursitis in end-stage renal disease. ( 30421305 )
2018
22
Ultrasonographic Diagnosis of Tumoral Calcinosis in End-Stage Renal Disease. ( 30060796 )
2018
23
Sudden cardiac arrest in end-stage renal disease patients on dialysis: A nationwide study. ( 30225901 )
2018
24
A Calculated Risk: Performing Laparoscopic Cholecystectomy for Acute Cholecystitis on Patients with End Stage Renal Disease. ( 29981632 )
2018
25
Open Versus Endovascular Revascularization of Below-Knee Arteries in Patients With End-Stage Renal Disease and Critical Limb Ischemia. ( 30021493 )
2018
26
Association between End-Stage Renal Disease and Incident Diabetes Mellitus-A Nationwide Population-Based Cohort Study. ( 30314341 )
2018
27
Peritoneal Dialysis as an Option for Unplanned Dialysis Initiation in Patients with End-Stage Renal Disease and Diabetes Mellitus. ( 30223256 )
2018
28
Diabetes mellitus and end-stage renal disease. ( 30152445 )
2018
29
The rate of progression of type 2 diabetes mellitus to end stage renal disease - A single centred retrospective study from Malaysia. ( 30168425 )
2018
30
Dyspepsia Amongst End Stage Renal Disease Undergoing Hemodialysis: Views from a Large Tertiary Care Center. ( 29984202 )
2018
31
Dysphagia in a Patient With End-Stage Renal Disease. ( 30201344 )
2018
32
Clinical presentations of contrast-induced encephalopathy in end-stage renal disease. ( 29722192 )
2018
33
Temporary Visual Loss Due to Posterior Reversible Encephalopathy Syndrome in the Case of an End-Stage Renal Disease Patient. ( 29467807 )
2018
34
Childhood kidney disease is associated with increased risk of end-stage renal failure in adulthood. ( 29853551 )
2018
35
Vaccination practices in End Stage Renal Failure and Renal Transplantation; Review of current guidelines and recommendations. ( 29988933 )
2018
36
An atypical p.N215S variant of Fabry disease with end-stage renal failure. ( 30023289 )
2018
37
Simultaneous Ipsilateral Quadriceps and Triceps Tendon Rupture in a Patient with End-Stage Renal Failure. ( 30155330 )
2018
38
The influence of hypothyroidism and substitution treatment on thyroid hormone conversion ratios and rT3 concentration in patients with end-stage renal failure. ( 30480752 )
2018
39
Native valve endocarditis, fusarium and end-stage renal disease. ( 29622705 )
2018
40
Systematic DNA Study for Fabry Disease in the End Stage Renal Disease Patients from a Southern Italy Area. ( 30099469 )
2018
41
Results of Fabry Disease Screening in Male Pre-End Stage Renal Disease Patients with Unknown Etiology Found Through the Platform of a Chronic Kidney Disease Education Program in a Northern Taiwan Medical Center. ( 30380558 )
2018
42
Safety of Laparoscopic Radical Gastrectomy in Gastric Cancer Patients with End-Stage Renal Disease. ( 30276005 )
2018
43
Incidence of glomerulonephritis and non-diabetic end-stage renal disease in a developing middle-east region near armed conflict. ( 30305040 )
2018
44
Isolated end-stage renal disease in Sjögren's syndrome due to immune complex mediated glomerulonephritis. ( 30524747 )
2018
45
Impact of Proteinase 3 versus Myeloperoxidase Positivity on Risk of End-Stage Renal Disease in ANCA-Associated Glomerulonephritis Stratified by Histological Classification: A Population-Based Cohort Study. ( 29854025 )
2018
46
Improved survival with renal transplantation for end-stage renal disease due to granulomatosis with polyangiitis: data from the United States Renal Data System. ( 29760156 )
2018
47
Re: Race, Risk, and Willingness of End-Stage Renal Disease Patients without Hepatitis C Virus to Accept an HCV-Infected Kidney Transplant. ( 30412962 )
2018
48
Hepatitis C virus infection in patients with end-stage renal disease. ( 30141571 )
2018
49
Rationale for treatment of hepatitis C virus infection in end-stage renal disease patients who are not kidney transplant candidates. ( 29694728 )
2018
50
'Real-life' experience with direct-acting antiviral agents for hepatitis C virus in end-stage renal disease. ( 29582685 )
2018

Variations for End Stage Renal Failure

Expression for End Stage Renal Failure

Search GEO for disease gene expression data for End Stage Renal Failure.

Pathways for End Stage Renal Failure

Pathways related to End Stage Renal Failure according to GeneCards Suite gene sharing:

(show all 20)
# Super pathways Score Top Affiliating Genes
1 12.7 AGTR1 COL4A5 EPO IL6 TGFB1
2
Show member pathways
12.18 ALB CRP IL6 TNF
3
Show member pathways
12.05 ACE IL6 TGFB1 TNF
4 11.88 ALB IL6 TGFB1 WT1
5 11.85 AGT IL6 TGFB1 TNF
6 11.72 IL6 TGFB1 TNF
7
Show member pathways
11.69 AGT CRP IL6
8 11.65 COL4A5 IL6 TGFB1 TNF
9 11.61 IL6 TGFB1 TNF
10 11.59 IL6 TGFB1 TNF
11 11.53 ACE AGT AGTR1
12 11.5 IL6 TGFB1 TNF
13
Show member pathways
11.46 ACE AGT AGTR1 TGFB1
14 11.36 IL6 TGFB1 TNF
15 11.35 AGTR1 COL4A5 IL6 TGFB1 TNF
16 11.31 IL6 PTH TNF
17 11.14 EPO IL6 TF TGFB1
18 11.04 IL6 TGFB1 TNF
19 10.97 COL4A5 MYH9 NPHS1 NPHS2 TGFB1 WT1
20 10.78 CRP IL6 TNF

GO Terms for End Stage Renal Failure

Cellular components related to End Stage Renal Failure according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.85 ACE AGT ALB CST3 MYH9 NPHS1
2 extracellular region GO:0005576 9.77 ACE AGT ALB COL4A5 CRP CST3
3 endoplasmic reticulum lumen GO:0005788 9.65 ALB COL4A5 CST3 IL6 TF
4 blood microparticle GO:0072562 9.62 AGT ALB TF TGFB1
5 extracellular space GO:0005615 9.4 ACE AGT ALB COL4A5 CRP CST3
6 slit diaphragm GO:0036057 9.37 NPHS1 NPHS2

Biological processes related to End Stage Renal Failure according to GeneCards Suite gene sharing:

(show all 32)
# Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 9.93 ALB CST3 IL6 TF
2 regulation of cell proliferation GO:0042127 9.9 AGT AGTR1 TGFB1 TNF
3 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.88 AGT IL6 TGFB1 TNF
4 regulation of signaling receptor activity GO:0010469 9.88 AGT EPO IL6 PTH TGFB1 TNF
5 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.83 AGT IL6 TGFB1
6 positive regulation of peptidyl-serine phosphorylation GO:0033138 9.83 IL6 TGFB1 TNF
7 positive regulation of inflammatory response GO:0050729 9.82 AGT AGTR1 TNF
8 negative regulation of fat cell differentiation GO:0045599 9.77 IL6 TGFB1 TNF
9 acute-phase response GO:0006953 9.7 CRP EPO IL6
10 excretion GO:0007588 9.69 NPHS1 NPHS2 UMOD
11 glomerular basement membrane development GO:0032836 9.64 NPHS1 WT1
12 positive regulation of cholesterol esterification GO:0010873 9.64 AGT AGTR1
13 response to salt stress GO:0009651 9.63 EPO TNF
14 neutrophil mediated immunity GO:0002446 9.62 ACE IL6
15 positive regulation of NAD(P)H oxidase activity GO:0033864 9.61 AGT AGTR1
16 positive regulation of neuroinflammatory response GO:0150078 9.61 IL6 TNF
17 metanephric ascending thin limb development GO:0072218 9.57 PKD1 UMOD
18 negative regulation of extracellular matrix disassembly GO:0010716 9.56 CST3 TGFB1
19 regulation of renal sodium excretion GO:0035813 9.55 AGT AGTR1
20 renin-angiotensin regulation of aldosterone production GO:0002018 9.54 AGT AGTR1
21 regulation of vasoconstriction GO:0019229 9.54 ACE AGT AGTR1
22 positive regulation of cellular protein metabolic process GO:0032270 9.5 AGT AGTR1 TGFB1
23 positive regulation of mononuclear cell migration GO:0071677 9.49 TGFB1 TNF
24 regulation of blood vessel diameter by renin-angiotensin GO:0002034 9.48 AGT AGTR1
25 mononuclear cell proliferation GO:0032943 9.46 ACE TGFB1
26 regulation of renal output by angiotensin GO:0002019 9.43 ACE AGT
27 positive regulation of superoxide anion generation GO:0032930 9.43 AGT CRP TGFB1
28 kidney development GO:0001822 9.35 ACE AGT AGTR1 PKD1 WT1
29 negative regulation of lipid storage GO:0010888 9.33 CRP IL6 TNF
30 regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 8.8 ACE AGT AGTR1
31 positive regulation of transcription, DNA-templated GO:0045893 10.06 AGT EPO IL6 TGFB1 TNF WT1
32 positive regulation of gene expression GO:0010628 10.02 CRP IL6 TGFB1 TNF WT1

Molecular functions related to End Stage Renal Failure according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.26 EPO IL6 TGFB1 TNF
2 bradykinin receptor binding GO:0031711 8.62 ACE AGTR1

Sources for End Stage Renal Failure

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