MCID: END030
MIFTS: 56

End Stage Renal Failure

Categories: Nephrological diseases

Aliases & Classifications for End Stage Renal Failure

MalaCards integrated aliases for End Stage Renal Failure:

Name: End Stage Renal Failure 38 12 15
Chronic Kidney Disease Stage 5 73
End Stage Renal Disease 12
Kidney Failure, Chronic 73

Classifications:



External Ids:

Disease Ontology 12 DOID:783
UMLS 73 C2316810

Summaries for End Stage Renal Failure

MalaCards based summary : End Stage Renal Failure, also known as chronic kidney disease stage 5, is related to frasier syndrome and nephrotic syndrome, type 1, and has symptoms including cloudy (hemodialysis) (peritoneal) dialysis effluent An important gene associated with End Stage Renal Failure is UMOD (Uromodulin), and among its related pathways/superpathways are Folate Metabolism and Dilated cardiomyopathy (DCM). The drugs Capsaicin and Simvastatin have been mentioned in the context of this disorder. Affiliated tissues include kidney, heart and bone, and related phenotypes are homeostasis/metabolism and cardiovascular system

Wikipedia : 76 Chronic kidney disease (CKD) is a type of kidney disease in which there is gradual loss of kidney... more...

Related Diseases for End Stage Renal Failure

Diseases related to End Stage Renal Failure via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 358)
# Related Disease Score Top Affiliating Genes
1 frasier syndrome 33.3 NPHS1 NPHS2 WT1
2 nephrotic syndrome, type 1 33.3 NPHS1 NPHS2 WT1
3 alport syndrome, x-linked 31.4 CD79A COL4A5 MYH9
4 peritonitis 31.2 ALB CRP IL6 TNF
5 secondary hyperparathyroidism of renal origin 31.0 ALB EPO PTH
6 calciphylaxis 30.9 ALB EPO PTH
7 poems syndrome 30.5 EPO IL6 TNF
8 infective endocarditis 30.4 CRP IL6 TNF
9 leptospirosis 30.4 CRP IL6 TNF
10 brucellosis 30.3 CRP IL6 TNF
11 endocarditis 30.3 ALB CRP IL6 TNF
12 autosomal dominant polycystic kidney disease 30.2 ACE AGT ALB PKD1
13 peripheral vascular disease 30.1 ACE ALB CRP IL6
14 peripheral artery disease 30.1 ACE CRP CST3 IL6
15 aortic valve disease 2 30.1 ACE AGT CRP
16 gingivitis 29.8 CD79A IL6 TNF
17 nephrosclerosis 29.7 ACE NPHS2 TGFB1
18 pyelonephritis 29.6 ACE ALB CRP IL6 TNF UMOD
19 arteries, anomalies of 29.5 ACE AGT ALB CRP IL6 TNF
20 interstitial nephritis 29.5 ACE AGT ALB ANKS6 CRP UMOD
21 microvascular complications of diabetes 3 29.4 ACE AGT ALB NPHS1 TGFB1
22 spinal cord injury 29.3 IL6 TGFB1 TNF
23 vascular disease 29.3 ACE ALB CRP CST3 IL6 TNF
24 coronary artery anomaly 29.1 ACE AGT CRP CST3 IL6
25 diabetes mellitus 29.1 ACE AGT ALB CRP EPO IL6
26 myeloma, multiple 29.0 ALB CD79A CRP EPO IL6 TNF
27 diabetes mellitus, noninsulin-dependent 28.9 ACE AGT ALB CRP IL6 TNF
28 glomerulonephritis 28.6 ALB CD79A COL4A5 NPHS1 NPHS2 TGFB1
29 posterior urethral valves 28.5 ACE AGT IL6 TGFB1 TNF
30 iga glomerulonephritis 28.1 ACE ALB CD79A IL6 NPHS1 NPHS2
31 kidney disease 22.5 ACE AGT ALB CD79A COL4A5 CRP
32 chronic kidney failure 21.5 ACE AGT ALB CD79A COL4A5 CRP
33 bardet-biedl syndrome 12 11.3
34 nephronophthisis 11.3
35 glomerulopathy with fibronectin deposits 2 11.2
36 medullary cystic kidney disease 1 11.1
37 nephrotic syndrome, type 2 11.1
38 medullary cystic kidney disease 2 11.1
39 nephronophthisis-like nephropathy 1 11.1
40 coenzyme q10 deficiency, primary, 6 11.1
41 nephronophthisis 20 11.1
42 nephrotic syndrome 15 11.1
43 familial idiopathic steroid-resistant nephrotic syndrome with minimal changes 11.1 NPHS1 NPHS2
44 familial idiopathic steroid-resistant nephrotic syndrome with diffuse mesangial sclerosis 11.0 NPHS1 WT1
45 glomerulopathy with fibronectin deposits 1 11.0
46 hematuria, benign familial 11.0
47 hyperuricemic nephropathy, familial juvenile, 1 11.0
48 hemolytic uremic syndrome, atypical 1 11.0
49 nephrotic syndrome, type 4 11.0
50 nephrotic syndrome, type 3 11.0

Graphical network of the top 20 diseases related to End Stage Renal Failure:



Diseases related to End Stage Renal Failure

Symptoms & Phenotypes for End Stage Renal Failure

UMLS symptoms related to End Stage Renal Failure:


cloudy (hemodialysis) (peritoneal) dialysis effluent

MGI Mouse Phenotypes related to End Stage Renal Failure:

46 (show all 12)
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.38 ACE AGT ALB CD79A COL4A5 CRP
2 cardiovascular system MP:0005385 10.37 ACE AGT ANKS6 COL4A5 CRP CST3
3 growth/size/body region MP:0005378 10.27 ACE AGT ANKS6 IL6 MYH9 NPHS2
4 cellular MP:0005384 10.22 ALB CD79A EPO IL6 MYH9 PKD1
5 hematopoietic system MP:0005397 10.21 TF TGFB1 TNF WT1 ACE CD79A
6 immune system MP:0005387 10.21 ACE AGT CD79A COL4A5 CRP EPO
7 mortality/aging MP:0010768 10.19 ACE AGT ALB ANKS6 COL4A5 CST3
8 adipose tissue MP:0005375 10.11 ACE AGT COL4A5 IL6 PKD1 TGFB1
9 liver/biliary system MP:0005370 10.06 ALB ANKS6 CD79A EPO IL6 PKD1
10 muscle MP:0005369 9.81 TGFB1 TNF WT1 AGT ALB CST3
11 neoplasm MP:0002006 9.61 TGFB1 TNF WT1 ACE ALB CD79A
12 renal/urinary system MP:0005367 9.44 NPHS2 PKD1 TGFB1 UMOD WT1 ACE

Drugs & Therapeutics for End Stage Renal Failure

Drugs for End Stage Renal Failure (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 749)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Capsaicin Approved Phase 4 404-86-4 1548943
2
Simvastatin Approved Phase 4,Not Applicable 79902-63-9 54454
3
Peginterferon alfa-2b Approved Phase 4,Phase 1,Not Applicable 99210-65-8, 215647-85-1
4
Ribavirin Approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 36791-04-5 37542
5
Nitric Oxide Approved Phase 4,Phase 1,Phase 2,Not Applicable 10102-43-9 145068 160954
6
Digoxin Approved Phase 4 20830-75-5 30322 2724385
7
Aspirin Approved, Vet_approved Phase 4 50-78-2 2244
8
Acetylcysteine Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 616-91-1 12035
9
Clopidogrel Approved Phase 4,Phase 3,Not Applicable 120202-66-6, 113665-84-2 60606
10
Ticagrelor Approved Phase 4,Phase 3,Phase 1,Phase 2 274693-27-5 9871419
11
Ticlopidine Approved Phase 4,Phase 3 55142-85-3 5472
12
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 3 113775-47-6 68602 5311068
13
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 3 2078-54-8 4943
14
alemtuzumab Approved, Investigational Phase 4,Phase 1,Phase 2 216503-57-0
15
Benzocaine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 1994-09-7, 94-09-7 2337
16
Tacrolimus Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 104987-11-3 445643 439492
17
Ursodeoxycholic acid Approved, Investigational Phase 4 128-13-2 31401
18
Oxycodone Approved, Illicit, Investigational Phase 4 76-42-6 5284603
19
Spironolactone Approved Phase 4,Phase 3,Phase 2,Not Applicable 1952-01-7, 52-01-7 5833
20
Bupivacaine Approved, Investigational Phase 4,Phase 3,Not Applicable 2180-92-9, 38396-39-3 2474
21
Lidocaine Approved, Vet_approved Phase 4,Not Applicable 137-58-6 3676
22
Pregabalin Approved, Illicit, Investigational Phase 4 148553-50-8 5486971
23
Alendronate Approved Phase 4,Not Applicable 121268-17-5, 66376-36-1 2088
24
Furosemide Approved, Vet_approved Phase 4,Phase 3,Phase 1,Not Applicable 54-31-9 3440
25
Hydrochlorothiazide Approved, Vet_approved Phase 4,Phase 3,Not Applicable 58-93-5 3639
26
Acarbose Approved, Investigational Phase 4 56180-94-0 441184
27
Pioglitazone Approved, Investigational Phase 4,Phase 2,Not Applicable 111025-46-8 4829
28
Ezetimibe Approved Phase 4,Not Applicable 163222-33-1 150311
29 Benidipine Approved, Investigational Phase 4 105979-17-7
30
Fosinopril Approved Phase 4,Phase 3,Not Applicable 98048-97-6 55891
31
Amlodipine Approved Phase 4,Phase 3,Phase 2,Not Applicable 88150-42-9 2162
32
Everolimus Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 159351-69-6 6442177
33
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 22916-47-8 4189
34
Sirolimus Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 53123-88-9 5284616 6436030 46835353
35
Angiotensin II Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 68521-88-0, 4474-91-3, 11128-99-7 172198 65143
36
Colchicine Approved Phase 4,Phase 2 64-86-8 6167 2833
37
Mycophenolate mofetil Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 128794-94-5 5281078
38
Mycophenolic acid Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 24280-93-1 446541
39
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 9005-49-6 772 46507594
40 Taurolidine Approved, Investigational Phase 4,Phase 3 19388-87-5
41
Methylprednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 83-43-2 6741
42
Prednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 50-24-8 5755
43
Prednisone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 53-03-2 5865
44
Menthol Approved Phase 4,Phase 2,Not Applicable 2216-51-5 16666
45
Chlorhexidine Approved, Vet_approved Phase 4,Not Applicable 55-56-1 9552079 2713
46
Iron Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 7439-89-6 23925
47
Zinc Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 7440-66-6 23994
48
Telmisartan Approved, Investigational Phase 4,Phase 3,Not Applicable 144701-48-4 65999
49
Losartan Approved Phase 4,Phase 3,Not Applicable 114798-26-4 3961
50
Calcium acetate Approved, Investigational Phase 4,Phase 3,Not Applicable 62-54-4

Interventional clinical trials:

(show top 50) (show all 1969)
# Name Status NCT ID Phase Drugs
1 Qutenza for Critical Ischaemia in End Stage Renal Failure Unknown status NCT01704339 Phase 4 QUTENZA
2 Inspiratory Muscle Training in Patients With End Stage Renal Failure Unknown status NCT01347775 Phase 4
3 Effect of Sodium Rinsing Fluid on Blood Pressure and Interdialytic Weight Change in Hemodialysis Patients Unknown status NCT02590081 Phase 4 Dextrose 5%;normal saline
4 Simvastatin Effect on End Stage Renal Failure Patients Treated by Peritoneal Dialysis Unknown status NCT00291863 Phase 4 Simvastatin
5 A Pilot Study to Treat Patients With Chronic Hepatitis C Virus (HCV) Genotype 1 and End-Stage Renal Disease (ESRD) Unknown status NCT01731301 Phase 4 Ribavirin;Peginterferon;Boceprevir
6 Far Infrared Therapy on AV Fistula Flow, Endothelial Function and Echocardiography in ESRD Patients Unknown status NCT01138254 Phase 4
7 Marinobufagenin as a Target for DIGIBIND in Hypertensive Patients With End-stage Renal Disease Unknown status NCT00852787 Phase 4 Digoxin immune fab;Placebo
8 Aspirin in the Prevention of Cardiovascular Events in Hemodialysis Patients Unknown status NCT01198379 Phase 4 aspirin;Placebo
9 Effect of Hydration With Sodium Bicarbonate for Long-Term Clinical Outcomes in Patients With Chronic Kidney Disease Undergoing an Emergent Coronary Procedure Unknown status NCT00716001 Phase 4 N-acetylcysteine
10 Platelet Resistance With Ticagrelor or Standard-Dose Clopidogrel Among CKD and ACS Patients Unknown status NCT02459288 Phase 4 Clopidogrel first;Ticagrelor first
11 NAC in Preventing CIN in CRF Patients Who Need Enhanced CT Scan in ED Unknown status NCT00501475 Phase 4 NAC Bicarbonate
12 Dexmedetomidine and Propofol As Sole Sedative Agent for Patients Undergoing Arteriovenous Fistula Surgery Unknown status NCT02447796 Phase 4 Propofol;Dexmedetomidine
13 Effects of On-Line Hemodiafiltration(HDF) on Vascular Health in Chronic Hemodialysis Patients Unknown status NCT00532597 Phase 4
14 Standard Versus Prolonged-release Tacrolimus Monotherapy After Alemtuzumab Induction in Kidney Transplantation Unknown status NCT00807144 Phase 4 Tacrolimus (Kidney transplant maintenance immunosuppression);Kidney transplant maintenance immunosuppression
15 A Study of Ferric Citrate to Improve Inflammation and Lipid Levels Unknown status NCT02661295 Phase 4 Ferric Citrate
16 Effect of Ursodeoxycholic Acid on Peritoneal Function in Patients on Peritoneal Dialysis Unknown status NCT02338635 Phase 4 Ursodeoxycholic Acid
17 Body Composition Monitor in Hemodialysis Patients Unknown status NCT01103167 Phase 4
18 Effect of Different Hemodialysis Modality on Adiponectin,Vascular Function and Clinical Prognosis Unknown status NCT00155363 Phase 4
19 Effects of an Exercise Program in Patients With Hypertensive Chronic Kidney Disease Unknown status NCT01155128 Phase 4
20 Opioids in Chronic Kidney Disease Patients Undergoing Hemodialysis Unknown status NCT02452437 Phase 4 Oxycodone
21 Hypervolemia in ESRD Patients in Zonguldak (Prospective Study) Unknown status NCT01468363 Phase 4
22 Cardiovascular Protective Effect of Spironolactone in Hemodialysis Unknown status NCT00277693 Phase 4 Spironolactone (drug)
23 The Canadian Prevention of Renal and Cardiovascular Endpoints Trial Unknown status NCT00231803 Phase 4
24 Anti-Oxidant Effect on Peritoneal Membrane in Peritoneal Dialysis (PD) Patients Unknown status NCT01111422 Phase 4 N-acetylcysteine
25 RAAS Inhibitor Drugs in Dialysis Patients Unknown status NCT01635387 Phase 4 aliskiren
26 More Frequent Dialysis (>3 Treatments Per Week) Unknown status NCT00575497 Phase 4
27 2% Lidocaine Plus 0.5% Bupivacaine Versus 0.5% Bupivacaine in Brachial Block for Creation of Arteriovenous (AV) Fistula Unknown status NCT00993746 Phase 4 Bupivacaine plus lidocaine;Bupivacaine 30 ml
28 The Effect and Safety of the Seasonal Trivalent Influenza Vaccine in Chronic Kidney Disease Patients Not on Dialysis Unknown status NCT02105519 Phase 4
29 Far Infrared Therapy on Peripheral Artery Disease in Hemodialysis Patients Unknown status NCT01095549 Phase 4
30 Efficacy of Pregabalin in the Management of Chronic Uremic Pruritus Unknown status NCT01073501 Phase 4 Pregabalin;Placebo
31 Clinical Impact of Bacteriuria on Chronic Inflammation in Asymptomatic Hemodialysis Patients Unknown status NCT01570556 Phase 4
32 Clinical Trial Technology Development for the Validation of Surrogate Prognostic Markers in Patients With Diabetic Nephropathy Unknown status NCT01673204 Phase 4 Calcitriol;Placebo
33 Alendronate for Vascular Calcification in Peritoneal Dialysis Patients? Unknown status NCT00299572 Phase 4 alendronate (Fosamax)
34 Effect of Intravenous Acetadote on Incidence of Contrast Induced Nephropathy Unknown status NCT00939913 Phase 4 intravenous NAC;Placebo
35 Clinical Trial to Compare Effectiveness of Diuretics in Hemodialysis Patients With Residual Renal Function Unknown status NCT01977430 Phase 4 Hydrochlorothiazide and furosemide
36 Thiazolidinedione (TZD) on the Diabetic Retinopathy and Nephropathy Unknown status NCT01175486 Phase 4 Actos (Pioglitazone);Acarbose
37 Oxidative Stress Lowering Effect of Simvastatin and Atorvastatin. Unknown status NCT00404599 Phase 4 atrorvastatin 10mg;simvastatin 40mg
38 The Effects of Acetylcysteine on Alleviating Damage of Oxidative Stress in Hemodialysis Patients Unknown status NCT00247507 Phase 4 acetylcysteine
39 Ezetimibe/Simvastatin Combination in Proteinuric Nephropathy Unknown status NCT00861731 Phase 4 simvastatin;EZE/simvastatin;EZE/simvastatin
40 Benidipine and Hydrochlorothiazide in Fosinopril Treated Chronic Kidney Disease Patients With Hypertension Unknown status NCT02646397 Phase 4 Fosinopril;Benidipine;Hydrochlorothiazide
41 Revascularization of Renal Artery Stenosis Versus Medical Therapy for the Treatment of Ischemic Nephropathy Unknown status NCT01023373 Phase 4 Medical treatment
42 Study Response of 13-valent Conjugate Pneumococcal Vaccine in Patients With End Stage Renal Disease Completed NCT01974817 Phase 4
43 Effect of Dialysis on the Pharmacokinetics of Telavancin in Patients With Chronic Kidney Disease Stage 5 Completed NCT02392208 Phase 4 Telavancin
44 Influence of Amlodipine on the Mortality of Patients With End-Stage Renal Failure Completed NCT00124969 Phase 4 Amlodipine;Placebo
45 Parathyroidectomy in Endstage Renal Disease Completed NCT00745719 Phase 4
46 Evaluating Aranesp® for the Treatment of Anemia in African-American Subjects With Chronic Renal Failure (CRF) Receiving Hemodialysis Completed NCT00111995 Phase 4 Aranesp®
47 Interferon Treatment for Patients With Chronic Hepatitis C and End Stage Renal Disease Completed NCT00172809 Phase 4 Peginterferon alfa-2a;Interferon alfa-2a
48 EPO-BUL-01 - Study of the Optimization of Anemia Management of EPREX (Epoetin Alfa) in Predialysis Patients With Chronic Renal Failure Completed NCT00338000 Phase 4 Epoetin alfa
49 Does ALlopurinol Regress lefT Ventricular Hypertrophy in End Stage REnal Disease: The ALTERED Study Completed NCT01951404 Phase 4 Allopurinol;Placebo (for allopurinol)
50 Evaluating Aranesp® in Subjects With End Stage Renal Disease onChronic Hemodialysis Completed NCT00117104 Phase 4 Aranesp®

Search NIH Clinical Center for End Stage Renal Failure

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Genetic Tests for End Stage Renal Failure

Anatomical Context for End Stage Renal Failure

MalaCards organs/tissues related to End Stage Renal Failure:

41
Kidney, Heart, Bone, Endothelial, Liver, Testes, Bone Marrow

Publications for End Stage Renal Failure

Articles related to End Stage Renal Failure:

(show top 50) (show all 608)
# Title Authors Year
1
Coconut atrium secondary to end-stage renal failure treated with long-term haemodialysis. ( 29688397 )
2018
2
Once-weekly hemodialysis combined with low-protein and low-salt dietary treatment as a favorable therapeutic modality for selected patients with end-stage renal failure: a prospective observational study in Japanese patients. ( 29954331 )
2018
3
'Known unknowns - examining the burden of neurocognitive impairment in the end-stage renal failure population'. ( 29345092 )
2018
4
A novel heterozygous GLI2 mutation in a patient with congenital urethral stricture and renal hypoplasia/dysplasia leading to end-stage renal failure. ( 29318530 )
2018
5
The cardiovascular risk factor profiles among end-stage renal failure patients treated with continuous ambulatory peritoneal dialysis and intermittent hemodialysis. ( 29456216 )
2018
6
End-Stage Renal Failure Is an Independent Risk Factor for 1-Year Mortality After Hip Fracture Surgery. ( 29707413 )
2018
7
Nutrient intake assessed with Diet History Questionnaire II, in relation to long-term calcium-phosphate control in hemodialysis patients with end-stage renal failure. ( 29521065 )
2018
8
Childhood kidney disease is associated with increased risk of end-stage renal failure in adulthood. ( 29853551 )
2018
9
Peritonitis outcomes in patients with HIV and end-stage renal failure on peritoneal dialysis: a prospective cohort study. ( 28158991 )
2017
10
Atrial Fibrillation and End Stage Renal Failure in Patients Receiving Dialysis: Balancing the Risks and Benefits of Stroke Prevention. ( 28457737 )
2017
11
Sign and magnitude scaling properties of heart rate variability in patients with end-stage renal failure: Are these properties useful to identify pathophysiological adaptations? ( 28964157 )
2017
12
Trends in Lower Limb Revascularization Among Patients With End-Stage Renal Failure: Where Is the Journey Going, and How Far Have We Come? ( 29050630 )
2017
13
A pilot study of ultrasound evaluation of gastric emptying in patients with end-stage renal failure: a comparison with healthy controls. ( 28332186 )
2017
14
Pharmacokinetics of dexmedetomidine administered to patients with end-stage renal failure and secondary hyperparathyroidism undergoing general anaesthesia. ( 29247451 )
2017
15
Acute thyroiditis: An under-recognized complication of parathyroidectomy in end-stage renal failure patients with secondary hyperparathyroidism. ( 28621009 )
2017
16
Re: The Survival Benefit of Kidney Transplantation in the Setting of Combined Peripheral Arterial Disease and End-Stage Renal Failure. ( 28208552 )
2017
17
Haploidentical hematopoietic bone marrow transplantation followed by living kidney transplantation from the same donor in a sickle cell disease patient with end-stage renal failure. ( 28160086 )
2017
18
End-stage renal failure due to transthyretin amyloidosis after liver transplantation: outcomes in 19 registry cases. ( 28434351 )
2017
19
The effect of dialysis type on left atrial functions in patients with end-stage renal failure: A propensity score-matched analysis. ( 29226431 )
2017
20
Cardiac Autonomic Neuropathy Predicts All-Cause and Cardiovascular Mortality in Patients With End-Stage Renal Failure: AA 5-Year Prospective Study. ( 29142986 )
2017
21
Importance of RIFLE (Risk, Injury, Failure, Loss, and End-Stage Renal Failure) and AKIN (Acute Kidney Injury Network) in Hemodialysis Initiation and Intensive Care Unit Mortality. ( 28761207 )
2017
22
Nocturnal blood pressure non-dipping is not associated with increased left ventricular mass index in hypertensive children without end-stage renal failure. ( 27344339 )
2016
23
Comparison of clinical and laboratory parameters in patients with end-stage renal failure in the outcome of chronic glomerulonephritis and patients with end-stage renal failure in the outcome of other diseases. ( 28214807 )
2016
24
Mineral and bone disorders, morbidity and mortality in end-stage renal failure patients on chronic dialysis. ( 27004031 )
2016
25
Non-traumatic lower limb amputation in patients with end-stage renal failure on dialysis: an Australian perspective. ( 27277135 )
2016
26
Unusual cause of hypercalcaemia in end stage renal failure patients. ( 27866377 )
2016
27
Emergency cardiac double valve surgery in active infective endocarditis due to Acinetobacter baumannii with aortic root abscess in a patient with dialysis-dependent end-stage renal failure: a rare case report. ( 27915239 )
2016
28
CONTINUOUS AMBULATORY PERITONEAL DIALYSIS IN PATIENTS WITH HIV AND END-STAGE RENAL FAILURE. ( 27935535 )
2016
29
Crystalline cardiomyopathy due to secondary oxalosis after short-bowel syndrome and end-stage renal failure. ( 27008641 )
2016
30
Effects of hemodialysis on macular and retinal nerve fiber layer thicknesses in non-diabetic patients with end stage renal failure. ( 27279510 )
2016
31
Impact of HCV Infection on Diabetes Patients for the Risk of End-Stage Renal Failure. ( 26817874 )
2016
32
Prevalence and Risk Factors of Lower Limb Amputation in Patients with End-Stage Renal Failure on Dialysis: A Systematic Review. ( 27529033 )
2016
33
Reversal of end-stage renal failure using direct-acting antiviral agents for chronic hepatitis C. ( 27581262 )
2016
34
Angioplasty of forearm arteries as a finger salvage procedure for patient with end-stage renal failure. ( 27143949 )
2016
35
Role of Procalcitonin in Differential Diagnosis of Pneumonia and Pulmonary Congestion Associated With End-Stage Renal Failure. ( 27805517 )
2016
36
Defining myocardial tissue abnormalities in end-stage renal failure with cardiac magnetic resonance imaging using native T1 mapping. ( 27503805 )
2016
37
Metastatic pulmonary calcification in end-stage renal failure. ( 27486208 )
2016
38
Ocular Surface Disorders in a Group of Egyptian Children with End Stage Renal Failure on Dialysis: A Cross-Sectional Study. ( 26942000 )
2016
39
The survival benefit of kidney transplantation in the setting of combined peripheral arterial disease and end-stage renal failure. ( 26914805 )
2016
40
Mice lacking microRNAs in Pax8-expressing cells develop hypothyroidism and end-stage renal failure. ( 27090781 )
2016
41
Fever with intradialytic pelvic pain: a case of iliopsoas abscess complicated with Methicillin-sensitive Staphylococcus Aureus bacteraemia in an end stage renal failure patient. ( 27326946 )
2016
42
Use of Erythropoietin-Stimulating Agents (ESA) in Patients With End-Stage Renal Failure Decided to Forego Dialysis: Palliative Perspective. ( 26718957 )
2015
43
Predictor of cardiovascular risks in end stage renal failure patients on maintenance dialysis. ( 26870086 )
2015
44
Causes of end stage renal failure among haemodialysis patients in Khartoum State/Sudan. ( 26419536 )
2015
45
Sequential molecularly targeted drug therapy including axitinib for a patient with end-stage renal failure and metastatic renal cell carcinoma. ( 26306562 )
2015
46
Aetiology of Paediatric End-stage Renal Failure in Jordan: A Multicentre Study. ( 26684161 )
2015
47
Baroreflex activation therapy in patients with end-stage renal failure: proof of concept. ( 26335429 )
2015
48
Role of renin-angiotensin system inhibitors in retardation of progression of end-stage renal failure: a retrospective study. ( 26519376 )
2015
49
Pharmacokinetics and pharmacodynamics of pegloticase in patients with end-stage renal failure receiving hemodialysis. ( 25816806 )
2015
50
Calcific uraemic arteriolopathy in a patient with end-stage renal failure and chronic plaque psoriasis: could TNF-I+ inhibition help ameliorate disease progression? ( 25688703 )
2015

Variations for End Stage Renal Failure

Expression for End Stage Renal Failure

Search GEO for disease gene expression data for End Stage Renal Failure.

Pathways for End Stage Renal Failure

Pathways related to End Stage Renal Failure according to GeneCards Suite gene sharing:

(show all 18)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.17 ALB CRP IL6 TNF
2
Show member pathways
12.05 ACE IL6 TGFB1 TNF
3 11.88 ALB IL6 TGFB1 WT1
4 11.85 AGT IL6 TGFB1 TNF
5 11.77 CD79A EPO IL6 TNF
6 11.71 IL6 TGFB1 TNF
7
Show member pathways
11.68 AGT CRP IL6
8
Show member pathways
11.64 ACE AGT TGFB1
9 11.62 COL4A5 IL6 TGFB1 TNF
10 11.59 IL6 TGFB1 TNF
11 11.54 COL4A5 IL6 TGFB1 TNF
12 11.5 IL6 TGFB1 TNF
13 11.36 IL6 TGFB1 TNF
14 11.31 IL6 PTH TNF
15 11.02 IL6 TGFB1 TNF
16 10.97 COL4A5 MYH9 NPHS1 NPHS2 TGFB1 WT1
17 10.94 EPO IL6 TF TGFB1
18 10.61 CRP IL6 TNF

GO Terms for End Stage Renal Failure

Cellular components related to End Stage Renal Failure according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.9 ACE AGT ALB CRP CST3 MYH9
2 extracellular space GO:0005615 9.7 ACE AGT ALB CRP CST3 EPO
3 endoplasmic reticulum lumen GO:0005788 9.65 ALB COL4A5 CST3 IL6 TF
4 blood microparticle GO:0072562 9.62 AGT ALB TF TGFB1
5 extracellular region GO:0005576 9.44 ACE AGT ALB COL4A5 CRP CST3
6 slit diaphragm GO:0036057 9.37 NPHS1 NPHS2

Biological processes related to End Stage Renal Failure according to GeneCards Suite gene sharing:

(show all 23)
# Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 9.88 ALB CST3 IL6 TF
2 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.78 AGT IL6 TGFB1
3 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.78 AGT IL6 TGFB1 TNF
4 positive regulation of peptidyl-serine phosphorylation GO:0033138 9.77 IL6 TGFB1 TNF
5 negative regulation of fat cell differentiation GO:0045599 9.71 IL6 TGFB1 TNF
6 kidney development GO:0001822 9.67 ACE AGT PKD1 WT1
7 excretion GO:0007588 9.63 NPHS1 NPHS2 UMOD
8 regulation of signaling receptor activity GO:0010469 9.63 AGT EPO IL6 PTH TGFB1 TNF
9 acute-phase response GO:0006953 9.61 CRP EPO IL6
10 angiotensin maturation GO:0002003 9.6 ACE AGT
11 neutrophil mediated immunity GO:0002446 9.58 ACE IL6
12 response to salt stress GO:0009651 9.57 EPO TNF
13 glomerular basement membrane development GO:0032836 9.56 NPHS1 WT1
14 regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 9.55 ACE AGT
15 negative regulation of extracellular matrix disassembly GO:0010716 9.51 CST3 TGFB1
16 metanephric ascending thin limb development GO:0072218 9.49 PKD1 UMOD
17 positive regulation of mononuclear cell migration GO:0071677 9.4 TGFB1 TNF
18 regulation of renal output by angiotensin GO:0002019 9.32 ACE AGT
19 mononuclear cell proliferation GO:0032943 9.26 ACE TGFB1
20 positive regulation of superoxide anion generation GO:0032930 9.13 AGT CRP TGFB1
21 negative regulation of lipid storage GO:0010888 8.8 CRP IL6 TNF
22 positive regulation of cell proliferation GO:0008284 10.01 AGT CST3 EPO IL6 TGFB1
23 positive regulation of transcription, DNA-templated GO:0045893 10 AGT EPO IL6 TGFB1 TNF WT1

Molecular functions related to End Stage Renal Failure according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 8.92 EPO IL6 TGFB1 TNF

Sources for End Stage Renal Failure

3 CDC
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