Endocarditis disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: END033 MIFTS: 60	Endocarditis Categories: Blood diseases, Cardiovascular diseases, Respiratory diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs Expand all tables

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Aliases & Classifications for Endocarditis

MalaCards integrated aliases for Endocarditis:

Name: Endocarditis ¹² ⁷⁷ ⁵⁶ ⁴⁴ ⁴⁵ ¹⁵ ¹⁷ ⁷⁴ ⁶⁴

Classifications:

MalaCards categories:
Anatomical: Cardiovascular diseases Respiratory diseases Blood diseases

See all MalaCards categories (disease lists)

ICD10: ³⁴

Diseases of the circulatory system

Other forms of heart disease

Acute and subacute endocarditis

Acute endocarditis, unspecified

External Ids:

Disease Ontology ¹² DOID:10314

ICD9CM ³⁶ 421.9

MeSH ⁴⁵ D004696

NCIt ⁵¹ C34582 C35432

SNOMED-CT ⁶⁹ 56819008 91357005

ICD10 ³⁴ I33.9

EFO ¹⁷ EFO_0000465

UMLS ⁷⁴ C0014118 C0375268

Sources

Summaries for Endocarditis

MedlinePlus : ⁴⁴ Endocarditis, also called infective endocarditis (IE), is an inflammation of the inner lining of the heart. The most common type, bacterial endocarditis, occurs when germs enter your heart. These germs come through your bloodstream from another part of your body, often your mouth. Bacterial endocarditis can damage your heart valves. If untreated, it can be life-threatening. It is rare in healthy hearts. Risk factors include having An abnormal or damaged heart valve An artificial heart valve Congenital heart defects The signs and symptoms of IE can vary from person to person. They also can vary over time in the same person. Symptoms you might notice include fever, shortness of breath, fluid buildup in your arms or legs, tiny red spots on your skin, and weight loss. Your doctor will diagnose IE based on your risk factors, medical history, signs and symptoms, and lab and heart tests. Early treatment can help you avoid complications. Treatment usually involves high-dose antibiotics. If your heart valve is damaged, you may need surgery. If you're at risk for IE, brush and floss your teeth regularly, and have regular dental checkups. Germs from a gum infection can enter your bloodstream. If you are at high risk, your doctor might prescribe antibiotics before dental work and certain types of surgery. NIH: National Heart, Lung, and Blood Institute

MalaCards based summary : Endocarditis is related to marantic endocarditis and infective endocarditis, and has symptoms including angina pectoris, edema and chest pain. An important gene associated with Endocarditis is CRP (C-Reactive Protein), and among its related pathways/superpathways are Allograft rejection and Toll Comparative Pathway. The drugs Cefazolin and Dextrose USP and Rifampicin have been mentioned in the context of this disorder. Affiliated tissues include heart, skin and brain, and related phenotypes are Reduced mammosphere formation and hematopoietic system

Disease Ontology : ¹² A endocardium disease characterized by inflammation of the endocardium of the heart chambers and valves.

PubMed Health : ⁶⁴ About endocarditis: Endocarditis (EN-do-kar-DI-tis) is an infection of the inner lining of the heart chambers and valves. This lining is called the endocardium (en-do-KAR-de-um). The condition also is called infective endocarditis (IE).The term "endocarditis" also is used to describe an inflammation of the endocardium due to other conditions. This article only discusses endocarditis related to infection.IE occurs if bacteria, fungi, or other germs invade your bloodstream and attach to abnormal areas of your heart. The infection can damage your heart and cause serious and sometimes fatal complications.IE can develop quickly or slowly; it depends on what type of germ is causing it and whether you have an underlying heart problem. When IE develops quickly, it's called acute infective endocarditis. When it develops slowly, it's called subacute infective endocarditis.

Wikipedia : ⁷⁷ Endocarditis is an inflammation of the inner layer of the heart, the endocardium. It usually involves... more...

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Related Diseases for Endocarditis

Diseases in the Endocarditis family:

Subacute Bacterial Endocarditis

Diseases related to Endocarditis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 777)

#	Related Disease	Score	Top Affiliating Genes
1	marantic endocarditis	33.8	F2 PLAT SERPINC1
2	infective endocarditis	33.3	APOH AQP9 CRP F2 FCGR2A IL6
3	brucellosis	32.1	CRP CXCL8 IL10 IL6 TNF
4	q fever	31.5	IL10 IL6 TNF
5	rheumatic fever	31.1	IL10 IL6 TNF
6	pericarditis	31.1	CRP IL6 TNF
7	endomyocardial fibrosis	30.8	IL10 TNF
8	arthritis	30.6	CXCL8 IL10 IL6 TNF
9	spondylitis	30.5	CRP IL6 TNF
10	limb ischemia	30.5	IL6 TNF TNNI3
11	mycobacterium fortuitum	30.5	CXCL8 HSPD1 LACTB
12	myocarditis	30.5	IL6 TNF TNNI3
13	pericardial effusion	30.5	CRP IL6 PIK3C2A
14	adult-onset still's disease	30.4	CRP IL6 TNF
15	lupus erythematosus	30.4	APOH FCGR2A IL10 TNF
16	osteomyelitis	30.4	CXCL8 IL10 IL6 TNF
17	rheumatic heart disease	30.3	IL10 IL6 TNF VCAM1
18	heparin-induced thrombocytopenia	30.2	FCGR2A SERPINC1
19	intracranial embolism	30.2	F2 PLAT SERPINC1
20	temporal arteritis	30.2	APOH CRP IL6 TNF
21	dermatitis, atopic	30.2	CXCL8 EPX IL10 TNF
22	end stage renal failure	30.1	ALB CRP IL6 TNF
23	drug reaction with eosinophilia and systemic symptoms	30.1	CRP TNF
24	fasciitis	30.1	CXCL8 IL6 TNF
25	vasculitis	30.1	APOH CRP TNF VCAM1
26	melioidosis	30.1	IL10 IL6 TNF
27	thrombosis	30.1	APOH F2 PLAT SERPINC1
28	autoimmune myocarditis	30.1	IL6 TNF
29	human immunodeficiency virus infectious disease	30.1	IL10 IL6 TNF
30	purpura	30.1	APOH CRP F2 IL6 SERPINC1 TNF
31	acquired immunodeficiency syndrome	30.1	ALB IL10 IL6 TNF
32	sudden sensorineural hearing loss	30.0	APOH F2 IL6
33	acute cystitis	30.0	ALB CRP CXCL8 IL6
34	colitis	29.9	CXCL8 IL10 IL6 TNF
35	protein s deficiency	29.9	APOH F2 SERPINC1
36	typhoid fever	29.9	ALB CRP F2 IL6 TNF
37	echinococcosis	29.9	IL10 IL6 TNF
38	meningitis	29.9	ALB CRP CXCL8 FCGR2A IL10 IL6
39	complex regional pain syndrome	29.9	IL10 IL6 TNF
40	myeloma, multiple	29.9	ALB CRP CXCL8 IL6 TNF
41	polyarteritis nodosa	29.9	APOH CRP IL6
42	patent foramen ovale	29.8	APOH F2 PLAT SERPINC1
43	pyelonephritis	29.8	ALB CRP CXCL8 IL10 IL6 TNF
44	disseminated intravascular coagulation	29.8	F2 PIK3C2A PLAT SERPINC1
45	diabetes mellitus	29.8	ALB CRP HSPD1 IL6 PIK3C2A TNF
46	kawasaki disease	29.8	ALB CRP FCGR2A HSPD1 IL10 IL6
47	cardiogenic shock	29.8	IL6 PIK3C2A PLAT TNF
48	alcoholic liver cirrhosis	29.8	ALB CXCL8 F2
49	pneumonia	29.8	CRP CXCL8 IL10 IL6 LACTB PIK3C2A
50	spinal cord injury	29.8	CXCL8 IL6 TNF

Graphical network of the top 20 diseases related to Endocarditis:

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Symptoms & Phenotypes for Endocarditis

UMLS symptoms related to Endocarditis:

angina pectoris, edema, chest pain

GenomeRNAi Phenotypes related to Endocarditis according to GeneCards Suite gene sharing:

²⁷

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Reduced mammosphere formation	GR00396-S	9.17	ALB CXCL8 FCGR2A HSPD1 PIK3C2A SERPINC1

MGI Mouse Phenotypes related to Endocarditis:

⁴⁷

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	hematopoietic system	MP:0005397	10.03	AQP9 EPX F2 FCGR2A IL10 IL6
2	cardiovascular system	MP:0005385	10.02	CRP F2 IL10 IL6 PIK3C2A PLAT
3	homeostasis/metabolism	MP:0005376	9.97	ALB APOH AQP9 CRP F2 IL10
4	immune system	MP:0005387	9.77	AQP9 CRP EPX F2 FCGR2A IL10
5	mortality/aging	MP:0010768	9.44	ALB APOH F2 FCGR2A HSPD1 IL10

Sources

Drugs & Therapeutics for Endocarditis

PubMedHealth treatment related to Endocarditis: ⁶⁴

Infective endocarditis (IE) is treated with antibiotics and sometimes with heart surgery.

FDA approved drugs:

#	Drug Name	Active Ingredient(s) ¹⁹	Company	Approval Date
1	Cefazolin and Dextrose USP ¹⁹	CEFAZOLIN SODIUM	B Braun Medical	July 2000
FDA Label: Cefazolin and Dextrose USP Disease/s that Drug Treats:Various bacterial infections, septicemia, endocarditis, and perioperative prophylaxis Indications and Usage: ¹⁹ Cefazolin for Injection USP and Dextrose Injection USP is a cephalosporin antibacterial indicated in the treatment of the following infections caused by susceptible isolates of the designated microorganisms: Respiratory tract infections (1.1); urinary tract infections (1.2); skin and skin structure infections (1.3); biliary tract infections (1.4); bone and joint infections (1.5); genital infections (1.6); septicemia (1.7); endocarditis (1.8) and perioperative prophylaxis (1.9). DrugBank Targets: ¹⁶ Penicillin-binding protein 1A\|Penicillin-binding protein 1B\|Penicillin-binding protein 1C\|Penicillin-binding protein 2 Mechanism of Action: ¹⁹ Target: - Action: - FDA: Cefazolin is an antibacterial drug [see Microbiology (12.4)]. Cefazolin is a bactericidal agent that acts by inhibition of bacterial cell wall synthesis.

Drugs for Endocarditis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 241)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Rifampicin

Approved

Phase 4,Phase 3

13292-46-1

5381226 5458213

Vancomycin

Approved

Phase 4,Phase 3,Phase 2,Not Applicable

1404-90-6

441141 14969

Lidocaine

Approved, Vet_approved

Phase 4,Phase 2

137-58-6

3676

Daptomycin

Approved, Investigational

Phase 4,Phase 3,Phase 2,Not Applicable

103060-53-3

16129629

Ceftaroline fosamil

Approved, Investigational

Phase 4,Phase 1

229016-73-3

Fosfomycin

Approved

Phase 4

23155-02-4

446987

Imipenem

Approved

Phase 4

74431-23-5, 64221-86-9

104838

Racepinephrine

Approved

Phase 4

329-65-7

838

Hexetidine

Approved, Investigational

Phase 4

141-94-6

Epinephrine

Approved, Vet_approved

Phase 4

51-43-4

5816

Chlorhexidine

Approved, Vet_approved

Phase 4,Not Applicable

55-56-1

2713 9552079

Amoxicillin

Approved, Vet_approved

Phase 4,Phase 3,Phase 2

26787-78-0

33613

Warfarin

Approved

Phase 4,Not Applicable

81-81-2

6691 54678486

Cephalexin

Approved, Investigational, Vet_approved

Phase 4,Phase 2,Phase 3

15686-71-2

27447

Clavulanate

Approved, Vet_approved

Phase 4

58001-44-8

5280980

Clopidogrel

Approved

Phase 4,Not Applicable

120202-66-6, 113665-84-2

60606

Rivaroxaban

Approved

Phase 4,Not Applicable

366789-02-8

Edoxaban

Approved

Phase 4,Not Applicable

480449-70-5

Apixaban

Approved

Phase 4,Not Applicable

503612-47-3

10182969

Aspirin

Approved, Vet_approved

Phase 4,Not Applicable

50-78-2

2244

Phenprocoumon

Approved, Investigational

Phase 4

435-97-2

9908 54680692

Linezolid

Approved, Investigational

Phase 4,Phase 3

165800-03-3

441401

Oritavancin

Approved, Investigational

Phase 4

171099-57-3

16129632

Serine

Approved, Nutraceutical

Phase 4,Not Applicable

56-45-1

5951

Dabigatran

Investigational

Phase 4,Not Applicable

211914-51-1

Anti-Bacterial Agents

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable

Antibiotics, Antitubercular

Phase 4,Phase 2,Phase 3,Not Applicable

methicillin

Phase 4,Phase 3,Phase 2

Anti-Infective Agents

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable

Antitubercular Agents

Phase 4,Phase 3,Phase 2,Not Applicable

Anesthetics

Phase 4,Phase 3,Phase 2,Not Applicable

Central Nervous System Depressants

Phase 4,Phase 2,Not Applicable

Peripheral Nervous System Agents

Phase 4,Phase 3,Phase 2,Not Applicable

Sodium Channel Blockers

Phase 4,Phase 2

Anti-Arrhythmia Agents

Phase 4,Phase 2

Anesthetics, Local

Phase 4,Phase 2

Diuretics, Potassium Sparing

Phase 4,Phase 2

Antirheumatic Agents

Phase 4,Phase 2,Not Applicable

Analgesics, Non-Narcotic

Phase 4,Phase 2,Not Applicable

Analgesics

Phase 4,Phase 2,Not Applicable

Cyclooxygenase Inhibitors

Phase 4,Phase 2,Not Applicable

Anti-Inflammatory Agents, Non-Steroidal

Phase 4,Phase 2,Not Applicable

Anti-Inflammatory Agents

Phase 4,Phase 3,Phase 2,Not Applicable

beta-Lactams

Phase 4

Lactams

Phase 4

Adrenergic beta-Agonists

Phase 4

Chlorhexidine gluconate

Phase 4,Not Applicable

Anti-Infective Agents, Local

Phase 4,Not Applicable

Mydriatics

Phase 4

Autonomic Agents

Phase 4,Phase 3

Interventional clinical trials:

(show top 50) (show all 245)

#	Name	Status	NCT ID	Phase	Drugs
1	Rationale, Design and Methods for the Early Surgery in Infective Endocarditis Study (ENDOVAL)	Unknown status	NCT00624091	Phase 4
2	Pharmacokinetics/ Pharmacodynamics (PK/PD) Study of Vancomycin	Unknown status	NCT02443064	Phase 4	Vancomycin
3	Duration of Antibiotic Therapy in Community - Acquired Pneumonia	Unknown status	NCT01492387	Phase 4
4	Partial Oral Treatment of Endocarditis	Completed	NCT01375257	Phase 4	Oral treatment with antibiotics for endocarditis;Guideline treatment with parenteral antibiotics
5	Early Surgery Versus Conventional Treatment in Infective Endocarditis	Completed	NCT00750373	Phase 4
6	Fosfomycin Plus Imipenem for Treatment of Infective Endocarditis	Completed	NCT00871104	Phase 4	Fosfomycin and imipenem;Vancomycin
7	The Effect of Sodium Bicarbonate on Postoperative Renal Function in Infective Endocarditis Patients Undergoing Open Heart Surgery	Completed	NCT01920126	Phase 4	sodium bicarbonate;Saline
8	Diagnosis of Septicaemia by Detection of Microbial DNA in Blood in Severe Infections	Completed	NCT00709358	Phase 4
9	Bacteraemia Secondary to Tooth Extraction: Chlorhexidine Prophylaxis Protocols	Completed	NCT02150031	Phase 4	0.2% Chlorhexidine;1% Chlorhexidine;1% Chlorhexidine;Lidocaine plus adrenaline
10	Bacteremia in Periodontal Patients	Completed	NCT02215473	Phase 4	Chlorhexidine gluconate mouth rinse
11	World-wide Randomized Antibiotic Envelope Infection Prevention Trial	Completed	NCT02277990	Phase 4
12	The Value of 99mTc-Leukoscan® Scintigraphy in the Diagnosis of Infectious Endocarditis on Surgical Materials	Recruiting	NCT03112356	Phase 4	99mTc-Leukoscan® scintigraphy
13	An Oral Amoxicillin-Clavulanate Regimen to Prevent Bacteremia Following Dental Procedures	Recruiting	NCT02783404	Phase 4	Amoxicillin;Amoxicillin-Potassium Clavulanate
14	Daptomycin as Adjunctive Therapy for Staphylococcus Aureus Bacteremia	Recruiting	NCT02972983	Phase 4	Daptomycin
15	Left Atrial Appendage CLOSURE in Patients With Atrial Fibrillation Compared to Medical Therapy	Recruiting	NCT03463317	Phase 4	Acetylsalicylic acid;Clopidogrel;Dabigatran;Rivaroxaban;Apixaban;Edoxaban;Phenprocoumon;Warfarin
16	Oritavancin for Staphylococcus Aureus Infections in Opioid Users	Not yet recruiting	NCT03761953	Phase 4	Oritavancin Injection
17	Impact of Antibiotic Treatment Following Implantation of Cardiac Electronic Device on Patient's Outcome	Not yet recruiting	NCT03148444	Phase 4	cefalexin 500 mg qid or roxithromycin 150 mg bid
18	Daptomycin as an Adjuvant Agent in the Treatment of Enterococcal Native Valve Endocarditis.	Terminated	NCT00401960	Phase 4	Daptomycin
19	Phase 4 Efficacy and Safety Study of Cubicin® With and Without Combination Therapy in S. Aureus Infective Endocarditis (SAIE)	Terminated	NCT00638157	Phase 4	daptomycin;daptomycin and gentamicin
20	Safety and Efficacy of Strategy to Prevent Drug-Induced Nephrotoxicity in High-Risk Patients	Terminated	NCT01734694	Phase 4	Vancomycin;Ceftaroline;Daptomycin;Linezolid
21	The Role of Synbiotics in Reducing Post-Operative Infections in Patients Undergoing Cardiac Surgery: A Pilot Study	Terminated	NCT00164099	Phase 4	Synbiotic 2000
22	TRANscatheter or SurgIcal Aortic Valve ReplacemenT in All-Comers With Severe Aortic Valve Stenosis	Withdrawn	NCT02838199	Phase 4
23	Safety and Effectiveness Study of Perceval S Valve for Extended CE Mark	Unknown status	NCT01368666	Phase 2, Phase 3
24	Efficacy and Safety of Venus P-valve to Treat RVOT Stenosis With Pulmonary Regurgitation	Unknown status	NCT02071654	Phase 3
25	Minimally Invasive Transthoracic Device Closure in Perimembranous Ventricular Septal Defect	Unknown status	NCT02644330	Phase 2, Phase 3
26	Multi-center Trial of Percutaneous Pulmonary Valve Implantation With Venus-p	Unknown status	NCT02590679	Phase 2, Phase 3
27	Daptomycin in the Treatment of Subjects With Infective Endocarditis or Bacteremia Due to S. Aureus	Completed	NCT00093067	Phase 3	daptomycin
28	A Study of MK-3009 in Japanese Patients With Skin or Blood Stream Infections Caused by Methicillin-resistant Staphylococcus Aureus (MK-3009-002)	Completed	NCT00770341	Phase 3	Daptomycin 4 mg/kg;Comparator: vancomycin;Daptomycin 6 mg/kg
29	Population Pharmacokinetic (PK) Study of Multiple Doses of Cubicin® (Daptomycin) 10 mg/kg in Critical Care Patients Having Bacteremia, Endocarditis or Skin Soft Tissue Infections Due to Gram Positive Bacteria With Various Degrees of Renal Failure	Completed	NCT02142075	Phase 3	Daptomycin
30	Conservative Aortic Valve Surgery for Aortic Insufficiency and Aneurysms of the Aortic Root. CAVIAAR	Completed	NCT00478803	Phase 3
31	Early Antiretroviral Treatment and/or Early Isoniazid Prophylaxis Against Tuberculosis in HIV-infected Adults (ANRS 12136 TEMPRANO)	Completed	NCT00495651	Phase 3	Antiretroviral medications;Antiretroviral medications+Isoniazid prophylaxis;Antiretroviral medications;Antiretroviral medications+Isoniazid prophylaxis
32	Strategies Using Off-Patent Antibiotics for Methicillin Resistant S. Aureus "STOP MRSA"	Completed	NCT00729937	Phase 2, Phase 3	Cephalexin;Clindamycin;Trimethoprim-sulfamethoxazole
33	Oral Switch During Treatment of Left-sided Endocarditis Due to Multi-susceptible Streptococcus	Recruiting	NCT02701595	Phase 3	Amoxicillin
34	Oral Switch During Treatment of Left-sided Endocarditis Due to Multi-susceptible Staphylococcus	Recruiting	NCT02701608	Phase 3	Levofloxacin;Rifampicin
35	Ceftobiprole in the Treatment of Patients With Staphylococcus Aureus Bacteremia	Recruiting	NCT03138733	Phase 3	Ceftobiprole medocaril;Daptomycin
36	Staphylococcus Aureus Bacteremia Antibiotic Treatment Options	Recruiting	NCT01792804	Phase 3	Trimethoprim-Sulfamethoxazole;Clindamycin;Linezolid;Flucloxacillin;Cloxacillin;Vancomycin;Daptomycin;Cefazolin
37	Transfer Factor Efficacy in the Management of Cirrhosis-associated Immune Dysfunction	Recruiting	NCT02837939	Phase 2, Phase 3	Human derived Transfer factor;Aqua pro injectione 4ml ampules for subcutaneous injection
38	STeroids to REduce Systemic Inflammation After Neonatal Heart Surgery	Recruiting	NCT03229538	Phase 3	Methylprednisolone;Isotonic saline
39	Effect of Nitric Oxide in Cardiac Surgery Patients With Endothelial Dysfunction.	Recruiting	NCT02836899	Phase 3	Nitric Oxide
40	A Phase 3 Telavancin Staphylococcus Aureus (S. Aureus) Bacteremia Trial	Terminated	NCT02208063	Phase 3	Telavancin;Vancomycin;Daptomycin;Synthetic penicillin;Cefazolin
41	Linezolid in the Treatment of Hemodialysis Patients With Catheter-Related Gram-Positive Bloodstream Infections	Terminated	NCT00108433	Phase 3	Cefazolin IV;Linezolid IV;Vancomycin (IV)
42	Perioperative Ketorolac-lidocaine in the Patients With Valvular Heart Diseases During Cesarean Delivery	Unknown status	NCT01571791	Phase 2	Placebo;Ketorolac-Lidocaine
43	TranScatheter Aortic Valve RepLacement System US Feasibility Trial	Unknown status	NCT01932099	Phase 2
44	Bacteria Entering the Blood Stream From Tooth Extractions and Tooth Brushing	Completed	NCT00454285	Phase 2	Effect of Amoxicillin on bacteremia following a single-tooth extraction
45	Safety Evaluation of a Q-fever Vaccine, NDBR 105	Completed	NCT00584454	Phase 2
46	Feasibility Study of a Percutaneous Mitral Valve Repair System.	Completed	NCT00209339	Phase 1, Phase 2
47	Assessment of Radiolabeled rhAnnexin V-128 in Infective Endocarditis	Recruiting	NCT02459613	Phase 1, Phase 2
48	Neonatal Vancomycin Trial	Recruiting	NCT02790996	Phase 2	Vancomycin
49	Surgical Implantation of TRAnscatheter vaLve in Native Mitral Annular Calcification (SITRAL) Study	Recruiting	NCT02830204	Phase 1, Phase 2
50	Evaluation of an Antibiotic Regimen Pharmacokinetic Applicable to Enterococcus Faecalis Infective Endocarditis	Active, not recruiting	NCT03681431	Phase 2	Ceftriaxone 4g/ 24h;Ceftriaxone 2g/ 12h

Search NIH Clinical Center for Endocarditis

Inferred drug relations via UMLS ⁷⁴ / NDF-RT ⁵² :

gentamicin sulfate pwdr

Cochrane evidence based reviews: endocarditis

Sources

Genetic Tests for Endocarditis

Sources

Anatomical Context for Endocarditis

MalaCards organs/tissues related to Endocarditis:

⁴²

Heart, Skin, Brain, Testes, Liver, Kidney, Colon

Sources

Publications for Endocarditis

Articles related to Endocarditis:

(show top 50) (show all 6560)

#	Title	Authors	Year
1	Rothia dentocariosa Endocarditis in an Unsuspecting Host: A Case Report and Literature Review. ( 30809399 )	Willner S...Hader I	2019
2	Efficacy of teicoplanin monotherapy following initial standard therapy in Enterococcus faecalis infective endocarditis: a retrospective cohort study. ( 30809761 )	De Nada? T...Martin-Blondel G	2019
3	Spodiobacter cordis gen. nov. sp. nov., a member of the family Flavobacteriaceae isolated from patients with infective endocarditis. ( 30817020 )	Tomida J...Kawamura Y	2019
4	Intravenous Drug Use-Associated Endocarditis Complicating Research of Antibiotic Prophylaxis and Guideline Recommendations. ( 30819369 )	Eddinger JJ	2019
5	Reply: Intravenous Drug Use-Associated Endocarditis Complicating Research of Antibiotic Prophylaxis and Guideline Recommendations. ( 30819370 )	Thornhill MH...Baddour LM	2019
6	D-Dimer is a strong predictor of in-hospital mortality in patients with infective endocarditis. ( 30821726 )	Bar?? V?...Erol ?	2019
7	An Occult Aortocavitary Fistula Presenting as Apparent Tricuspid Valve and Aortic Valve Endocarditis. ( 30828681 )	Nguyen T...Richardson K	2019
8	Successful treatment of Pseudomonas aeruginosa infective endocarditis via haemodialysis outpatient parenteral antimicrobial therapy: case report. ( 30830217 )	Maxwell-Scott H...Klein JL	2019
9	Infective endocarditis in chronic hemodialysis patients is it still a growing clinical challenge? ( 30830890 )	Spaleniak S...Niemczyk S	2019
10	Response: Fundamental role of echocardiographic evaluation in the diagnosis of prosthetic valve endocarditis. ( 30834557 )	Carneiro H...Rasalingam R	2019
11	Acute ST-elevation myocardial infarction due to prosthetic valve endocarditis after transcatheter aortic valve implantation. ( 30836743 )	Cho JH...Kim HS	2019
12	Repair of left ventricular pseudoaneurysm from mitral valve endocarditis. ( 30843076 )	Govindasamy SP...Lim YP	2019
13	Pauci-immune proliferative glomerulonephritis and fungal endocarditis: More than a mere coincidence? ( 30846459 )	Aboud H...Koratala A	2019
14	Diagnostic challenges in infective endocarditis: is PET/CT the solution? ( 30847769 )	Hohmann C...Jung N	2019
15	In-host evolution of Staphylococcus epidermidis in a pacemaker-associated endocarditis resulting in increased antibiotic tolerance. ( 30850614 )	Dengler Haunreiter V...Zinkernagel AS	2019
16	Be careful about MICs to amoxicillin for patients with Streptococci-related infective endocarditis. ( 30851401 )	Pilmis B...GMC Study Group	2019
17	Severe tricuspid valve destruction secondary to previous non-appropriately treated endocarditis. ( 30852499 )	Sall F...Yangni-Angate H	2019
18	Tricuspid Valve Infective Endocarditis Due to Klebsiella pneumoniae in Intravenous Drug User. ( 30854255 )	Riangwiwat T...Dworkin J	2019
19	Evaluation of failed prosthetic valves in the valve-in-valve era: Potential for utilizing positron emission tomography/computed tomography to recognize infective endocarditis. ( 30856285 )	Lam DH...Dvir D	2019
20	Assessment of the feasibility of a partial oral regimen for antibiotic therapy of endocarditis. ( 30864091 )	Bellone P...Gruppo di Autoformazione Metodologica (GrAM)	2019
21	Duration and complications of diabetes mellitus and the associated risk of infective endocarditis. ( 30291010 )	?stergaard L...Fosb?l EL	2019
22	Plasmapheresis and corticosteroids in infective endocarditis-related crescentic glomerulonephritis. ( 30872338 )	Malhotra K...Yerram P	2019
23	Value of cardiac computed tomography angiography in pre-operative assessment of infective endocarditis. ( 30866989 )	Chaosuwannakit N...Makarawate P	2019
24	Clot Histopathology in Ischemic Stroke with Infective Endocarditis. ( 30867075 )	Bhaskar S...Cordato D	2019
25	Antimicrobial management of Tropheryma whipplei endocarditis: the Spanish Collaboration on Endocarditis (GAMES) experience. ( 30869125 )	Garc?a-?lvarez L...Spanish Collaboration on Endocarditis-Grupo de Apoyo al Manejo de la Endocarditis Infecciosa en Espa?a (GAMES)	2019
26	99mTc-Besilesomab-SPECT/CT in Infectious Endocarditis: Upgrade of a Forgotten Method? ( 30873410 )	Bouter C...Meller J	2019
27	Giant vegetation in mitral prosthetic heart valve endocarditis. ( 30874506 )	G?ner A...?zkan M	2019
28	Endocarditis after percutaneous edge-to-edge in a heart transplant recipient: management through the HeartPort technique. ( 30879051 )	Anselmi A...Verhoye JP	2019
29	Outcome for surgical treatment of infective endocarditis with periannular abscess. ( 30879717 )	Ting M...Yu HY	2019
30	Prosthetic Valve Legionella Endocarditis. ( 30880136 )	Young JS...Graver LM	2019
31	Myocarditis Caused by Brucella melitensis in the Absence of Endocarditis: Case Report and Review of the Literature. ( 30881458 )	Lagadinou M...Marangos M	2019
32	The 18-fluorine-fluorodeoxyglucose positron-emission-tomography/computed tomography-guided treatment of prosthetic valve endocarditis. ( 30882194 )	S?awi?ski G...Raczak G	2019
33	Long-Term Outcomes of Partial Oral Treatment of Endocarditis. ( 30883059 )	Bundgaard H...Iversen K	2019
34	Mitral valve endocarditis-Unrealized expectations for repair of mitral valve. ( 30885624 )	Nappi F...Spadaccio C	2019
35	Mitral valve repair versus replacement for infective endocarditis, again. ( 30885627 )	Antunes MJ	2019
36	Clinical hallmarks making diagnosis of infective endocarditis. ( 30887385 )	Tahara A...Fukumoto Y	2019
37	ST-Elevation Myocardial Infarction Associated With Infective Endocarditis. ( 30890259 )	Nazir S...Donato A	2019
38	Subacute Aerococcus urinae Infective Endocarditis With Mycotic Aneurysms in a Pediatric Patient: Case Report and Literature Review. ( 30892601 )	Sous N...Bhavsar SM	2019
39	Blocking a rash diagnosis: a rare case of infective endocarditis. ( 30898951 )	Halford B...Taylor C	2019
40	Group C Streptococcus dysgalactiae subsp.equisimilis (SDSE) Endocarditis with Endogenous Endophthalmitis and Aortic Root Abscess. ( 30899671 )	Yung L...Br?u N	2019
41	Whipple's endocarditis diagnosed by thrombus analysis retrieved by successful mechanical thrombectomy. ( 30901568 )	Elodie O...Nighoghossian N	2019
42	Commentary: Goals of surgical therapy in tricuspid valve endocarditis. ( 30901790 )	Weiss AJ...Anyanwu AC	2019
43	Role of age and comorbidities in mortality of patients with infective endocarditis. ( 30904433 )	Armi?anzas C...Segura Luque JC	2019
44	Nursing Home Admission and Initiation of Domiciliary Care Following Infective Endocarditis. ( 30905692 )	Havers-Borgersen E...Butt JH	2019
45	Management of endocarditis among persons who inject drugs: A narrative review of surgical and psychiatric approaches and controversies. ( 30908961 )	Elbatarny M...Hamilton A	2019
46	Right-sided endocarditis from Staphylococcus lugdunensis in a patient with tetralogy of Fallot. ( 30915201 )	Iii BB...Moody MA	2019
47	Trends in Epidemiology: Analysis of Risk Factors and Outcomes of Infective Endocarditis: A Retrospective Study (2009-2015). ( 30915267 )	Lin AN...Reddy S	2019
48	Addressing limitations of partial oral treatment of left-sided infectious endocarditis (POET) criteria for prosthetic valve endocarditis: a note of caution. ( 30916328 )	Veulemans V...Zeus T	2019
49	Infective Endocarditis Due to Treponema pallidum: A Case Diagnosed Using Polymerase Chain Reaction Analysis of Aortic Valve. ( 30595174 )	Hijikata S...Ashikaga T	2019
50	Candida Endocarditis after TAVR. ( 30601749 )	Carrel T...Eberle B	2019

Sources

Genes for Endocarditis

Genes related to Endocarditis (0 elite genes):

(show all 21)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	CRP	C-Reactive Protein	Protein Coding	23.52	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
2	F2	Coagulation Factor II, Thrombin	Protein Coding	22.36	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
3	EPX	Eosinophil Peroxidase	Protein Coding	21.99	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁶ GeneCards inferred via : Publications (show sections)	1985118 2002037
4	TNF	Tumor Necrosis Factor	Protein Coding	21.71	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
5	ALB	Albumin	Protein Coding	21.56	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
6	HSPD1	Heat Shock Protein Family D (Hsp60) Member 1	Protein Coding	21.54	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
7	LBP	Lipopolysaccharide Binding Protein	Protein Coding	21.19	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
8	PIK3C2A	Phosphatidylinositol-4-Phosphate 3-Kinase Catalytic Subunit Type 2 Alpha	Protein Coding	21.17	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
9	TNNI3	Troponin I3, Cardiac Type	Protein Coding	21.12	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
10	IL6	Interleukin 6	Protein Coding	21.12	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
11	CXCL8	C-X-C Motif Chemokine Ligand 8	Protein Coding	21.01	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
12	FCGR2A	Fc Fragment Of IgG Receptor IIa	Protein Coding	20.91	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
13	APOH	Apolipoprotein H	Protein Coding	20.87	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
14	SERPINC1	Serpin Family C Member 1	Protein Coding	20.55	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
15	VCAM1	Vascular Cell Adhesion Molecule 1	Protein Coding	20.46	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
16	IL10	Interleukin 10	Protein Coding	20.42	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
17	PLAT	Plasminogen Activator, Tissue Type	Protein Coding	20.39	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
18	LACTB	Lactamase Beta	Protein Coding	12.14	Novoseek inferred ⁵⁶ GeneCards inferred via : Publications (show sections)	8323254 1389104 2050588 (more) 8444668
19	CEACAM8	Carcinoembryonic Antigen Related Cell Adhesion Molecule 8	Protein Coding	11.14	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
20	AQP9	Aquaporin 9	Protein Coding	10.73	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
21	TLR2	Toll Like Receptor 2	Protein Coding	10.36	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)

Sources

Variations for Endocarditis

Sources

Expression for Endocarditis

Search GEO for disease gene expression data for Endocarditis.

Sources

Pathways for Endocarditis

Pathways related to Endocarditis according to GeneCards Suite gene sharing:

(show all 31)

#	Super pathways	Score	Top Affiliating Genes
1	Allograft rejection ¹ ³⁸ Show member pathways Antigen processing and presentation ³⁸ Asthma ³⁸ Autoimmune thyroid disease ³⁸ CTL Mediated Apoptosis ⁶⁵ Graft-versus-host disease ³⁸ Intestinal immune network for IgA production ³⁸ THC Differentiation Pathway ⁶⁵ Type I diabetes mellitus ³⁸ Viral myocarditis ³⁸	12.82	CXCL8 EPX HSPD1 IL10 IL6 TNF
2	Toll Comparative Pathway ⁶⁵ Show member pathways IL-1 Pathway ⁶⁵ Immune response MIF in innate immunity response ²³ iNOS Signaling ⁶⁵ TLR-TRIF Pathway ⁶⁵	12.24	CXCL8 IL6 LBP TNF
3	Selenium Micronutrient Network ¹ Show member pathways Folate Metabolism ¹ Metabolism of ingested MeSeO2H into MeSeH ⁶⁷ thioredoxin pathway ¹ Vitamin B12 Metabolism ¹	12.18	ALB CRP F2 IL6 PLAT TNF
4	Bacterial infections in CF airways ²³ Show member pathways IL-1 beta-dependent CFTR expression ²³ Immune response Bacterial infections in normal airways ²³ Immune response TLR signaling pathways ²³	12.14	CXCL8 IL6 LBP TNF
5	Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways ¹	12.1	CXCL8 HSPD1 IL10 IL6 TNF
6	Tuberculosis ³⁸	12.05	FCGR2A HSPD1 IL10 IL6 LBP TNF
7	Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers ⁶⁶	12.02	ALB IL6 TNNI3 VCAM1
8	Spinal Cord Injury ¹	11.96	CXCL8 FCGR2A IL6 TNF
9	Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers ⁶⁶	11.9	CEACAM8 FCGR2A IL10 IL6 TNF
10	AGE-RAGE signaling pathway in diabetic complications ³⁸	11.87	CXCL8 IL6 TNF VCAM1
11	Amoebiasis ³⁸	11.84	CXCL8 IL10 IL6 TNF
12	NF-kappa B signaling pathway ³⁸	11.83	CXCL8 LBP TNF VCAM1
13	Cytokine production by Th17 cells in CF (Mouse model) ²³ Show member pathways Cytokine production by Th17 cells in CF ²³	11.8	CXCL8 IL6 LBP
14	Rheumatoid arthritis ³⁸	11.78	CXCL8 IL6 TNF
15	Salmonella infection (KEGG) ³⁸	11.75	CXCL8 IL6 LBP
16	Microglia Activation During Neuroinflammation: Overview ⁶⁶ Show member pathways Microglia Activation During Neuroinflammation: Microglia Activation ⁶⁶	11.73	F2 FCGR2A HSPD1 IL6 PLAT TNF
17	Pertussis ³⁸	11.72	CXCL8 IL10 IL6 TNF
18	Dendritic Cells Developmental Lineage Pathway ⁶⁶	11.68	IL10 IL6 TNF
19	Microglia Activation During Neuroinflammation: Microglia Polarization ⁶⁶	11.68	FCGR2A IL10 IL6 TNF
20	Photodynamic therapy-induced NF-kB survival signaling ¹ Show member pathways Immune response MIF-mediated glucocorticoid regulation ²³	11.61	CXCL8 IL6 TNF VCAM1
21	Lung fibrosis ¹	11.6	CXCL8 IL6 TNF
22	Legionellosis ³⁸	11.52	CXCL8 HSPD1 IL6 TNF
23	amb2 Integrin signaling ¹	11.47	IL6 PLAT TNF
24	Interleukin-10 signaling ⁶⁷	11.45	CXCL8 IL10 IL6 TNF
25	IL-10 Pathway ⁶⁵	11.31	IL10 IL6 TNF
26	African trypanosomiasis ³⁸	11.27	IL10 IL6 TNF VCAM1
27	Cytokines and Inflammatory Response ¹	11.21	IL10 IL6 TNF
28	Interleukin-4 and 13 signaling ⁶⁷	11.16	CXCL8 IL10 IL6 LBP TNF VCAM1
29	G-protein signaling_RhoB regulation pathway ²³	11.15	CXCL8 IL10 IL6 TNF
30	Malaria ³⁸	11.04	CXCL8 IL10 IL6 TNF VCAM1
31	Overview of nanoparticle effects ¹	10.84	CRP CXCL8 IL6 TNF

Sources

GO Terms for Endocarditis

Cellular components related to Endocarditis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	extracellular exosome	GO:0070062	9.9	ALB APOH CEACAM8 EPX F2 HSPD1
2	cell surface	GO:0009986	9.8	APOH CEACAM8 HSPD1 LBP PLAT TNF
3	extracellular region	GO:0005576	9.73	ALB APOH CRP CXCL8 EPX F2
4	extracellular space	GO:0005615	9.5	ALB APOH CEACAM8 CRP CXCL8 EPX

Biological processes related to Endocarditis according to GeneCards Suite gene sharing:

(show all 27)

#	Name	GO ID	Score	Top Affiliating Genes
1	regulation of signaling receptor activity	GO:0010469	9.99	CXCL8 F2 IL10 IL6 TNF
2	inflammatory response	GO:0006954	9.96	CRP CXCL8 IL10 IL6 TNF
3	defense response to bacterium	GO:0042742	9.92	EPX IL10 LBP TNF
4	cellular protein metabolic process	GO:0044267	9.9	ALB F2 IL6 SERPINC1
5	defense response to Gram-positive bacterium	GO:0050830	9.81	CRP IL6 LBP TNF
6	cellular response to lipopolysaccharide	GO:0071222	9.77	CXCL8 IL10 IL6 LBP TNF
7	response to lipopolysaccharide	GO:0032496	9.72	IL10 LBP VCAM1
8	response to organic substance	GO:0010033	9.67	AQP9 IL10 TNF
9	positive regulation of chemokine production	GO:0032722	9.65	IL6 LBP TNF
10	positive regulation of blood coagulation	GO:0030194	9.63	APOH F2
11	response to molecule of bacterial origin	GO:0002237	9.63	CXCL8 IL10
12	positive regulation of macrophage activation	GO:0043032	9.63	HSPD1 IL10 LBP
13	cytokine-mediated signaling pathway	GO:0019221	9.63	CXCL8 IL10 IL6 LBP TNF VCAM1
14	plasminogen activation	GO:0031639	9.62	APOH PLAT
15	negative regulation of fibrinolysis	GO:0051918	9.61	APOH F2
16	opsonization	GO:0008228	9.61	CRP LBP
17	response to glucocorticoid	GO:0051384	9.61	IL10 IL6 TNF
18	endothelial cell apoptotic process	GO:0072577	9.58	IL10 TNF
19	negative regulation of cytokine secretion involved in immune response	GO:0002740	9.58	IL10 TNF
20	negative regulation of growth of symbiont in host	GO:0044130	9.58	IL10 LBP TNF
21	positive regulation of neuroinflammatory response	GO:0150078	9.57	IL6 TNF
22	positive regulation of interleukin-6 production	GO:0032755	9.56	HSPD1 IL6 LBP TNF
23	receptor biosynthetic process	GO:0032800	9.54	IL10 TNF
24	regulation of blood coagulation	GO:0030193	9.5	APOH F2 SERPINC1
25	negative regulation of lipid storage	GO:0010888	9.13	CRP IL6 TNF
26	acute-phase response	GO:0006953	8.92	CRP F2 IL6 LBP
27	immune response	GO:0006955	10	AQP9 CEACAM8 CXCL8 IL10 IL6 TNF

Molecular functions related to Endocarditis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	cytokine activity	GO:0005125	9.26	CXCL8 IL10 IL6 TNF
2	lipopolysaccharide binding	GO:0001530	8.8	F2 HSPD1 LBP

Sources

Sources for Endocarditis

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FDA Approved Drugs

²⁰ FMA

²¹ GeneAnalytics

²² GeneCards

²³ GeneGo (Thomson Reuters)

²⁴ GeneHancer via GeneCards

²⁵ GeneReviews

²⁶ Genetics Home Reference

²⁷ GenomeRNAi

²⁸ GEO DataSets

²⁹ GO

³⁰ GTR

³¹ HGMD

³² HMDB

³³ HPO

³⁴ ICD10

³⁵ ICD10 via Orphanet

³⁶ ICD9CM

³⁷ IUPHAR

³⁸ KEGG

³⁹ LifeMap

⁴⁰ LncRNADisease

⁴¹ LOVD

⁴² MalaCards

⁴³ MedGen

⁴⁴ MedlinePlus

⁴⁵ MeSH

⁴⁶ MESH via Orphanet

⁴⁷ MGI

⁴⁸ miR2Disease

⁴⁹ NCBI Bookshelf

⁵⁰ NCI

⁵¹ NCIt

⁵² NDF-RT

⁵³ NIH Clinical Center

⁵⁴ NIH Rare Diseases

⁵⁵ NINDS

⁵⁶ Novoseek

⁵⁷ Novus Biologicals

⁵⁸ OMIM

⁵⁹ OMIM via Orphanet

⁶⁰ Orphanet

⁶¹ PathCards

⁶² PharmGKB

⁶³ PubMed

⁶⁴ PubMed Health

⁶⁵ QIAGEN

⁶⁶ R&D Systems

⁶⁷ Reactome

⁶⁸ Sino Biological

⁶⁹ SNOMED-CT

⁷⁰ SNOMED-CT via HPO

⁷¹ SNOMED-CT via Orphanet

⁷² TGDB

⁷³ Tocris

⁷⁴ UMLS

⁷⁵ UMLS via Orphanet

⁷⁶ UniProtKB/Swiss-Prot

⁷⁷ Wikipedia

Endocarditis

Aliases & Classifications for Endocarditis

MalaCards integrated aliases for Endocarditis:

Classifications:

External Ids:

Summaries for Endocarditis

Related Diseases for Endocarditis

Diseases in the Endocarditis family:

Diseases related to Endocarditis via text searches within MalaCards or GeneCards Suite gene sharing:

Graphical network of the top 20 diseases related to Endocarditis:

Symptoms & Phenotypes for Endocarditis

UMLS symptoms related to Endocarditis:

GenomeRNAi Phenotypes related to Endocarditis according to GeneCards Suite gene sharing:

MGI Mouse Phenotypes related to Endocarditis:

Drugs & Therapeutics for Endocarditis

PubMedHealth treatment related to Endocarditis: 64

FDA approved drugs:

Drugs for Endocarditis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

Interventional clinical trials:

Inferred drug relations via UMLS 74 / NDF-RT 52 :

Cochrane evidence based reviews: endocarditis

Genetic Tests for Endocarditis

Anatomical Context for Endocarditis

MalaCards organs/tissues related to Endocarditis:

Publications for Endocarditis

Articles related to Endocarditis:

Genes for Endocarditis

Genes related to Endocarditis (0 elite genes):

Variations for Endocarditis

Expression for Endocarditis

Pathways for Endocarditis

Pathways related to Endocarditis according to GeneCards Suite gene sharing:

GO Terms for Endocarditis

Cellular components related to Endocarditis according to GeneCards Suite gene sharing:

Biological processes related to Endocarditis according to GeneCards Suite gene sharing:

Molecular functions related to Endocarditis according to GeneCards Suite gene sharing:

Sources for Endocarditis

PubMedHealth treatment related to Endocarditis: ⁶⁴

Inferred drug relations via UMLS ⁷⁴ / NDF-RT ⁵² :