Endocarditis disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: END033 MIFTS: 60	Endocarditis Categories: Blood diseases, Cardiovascular diseases, Respiratory diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs Expand all tables

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Aliases & Classifications for Endocarditis

MalaCards integrated aliases for Endocarditis:

Name: Endocarditis ¹² ⁷⁶ ⁵⁵ ⁴³ ⁴⁴ ¹⁵ ⁶³ ⁷³

Classifications:

MalaCards categories:
Anatomical: Cardiovascular diseases Respiratory diseases Blood diseases

See all MalaCards categories (disease lists)

ICD10: ³³

Diseases of the circulatory system

Other forms of heart disease

Acute and subacute endocarditis

Acute endocarditis, unspecified

External Ids:

Disease Ontology ¹² DOID:10314

ICD10 ³³ I33.9

ICD9CM ³⁵ 421.9

MeSH ⁴⁴ D004696

NCIt ⁵⁰ C34582 C35432

SNOMED-CT ⁶⁸ 56819008 91357005

UMLS ⁷³ C0014118 C0375268

Sources

Summaries for Endocarditis

MedlinePlus : ⁴³ Endocarditis, also called infective endocarditis (IE), is an inflammation of the inner lining of the heart. The most common type, bacterial endocarditis, occurs when germs enter your heart. These germs come through your bloodstream from another part of your body, often your mouth. Bacterial endocarditis can damage your heart valves. If untreated, it can be life-threatening. It is rare in healthy hearts. Risk factors include having An abnormal or damaged heart valve An artificial heart valve Congenital heart defects The signs and symptoms of IE can vary from person to person. They also can vary over time in the same person. Symptoms you might notice include fever, shortness of breath, fluid buildup in your arms or legs, tiny red spots on your skin, and weight loss. Your doctor will diagnose IE based on your risk factors, medical history, signs and symptoms, and lab and heart tests. Early treatment can help you avoid complications. Treatment usually involves high-dose antibiotics. If your heart valve is damaged, you may need surgery. If you're at risk for IE, brush and floss your teeth regularly, and have regular dental checkups. Germs from a gum infection can enter your bloodstream. If you are at high risk, your doctor might prescribe antibiotics before dental work and certain types of surgery. NIH: National Heart, Lung, and Blood Institute

MalaCards based summary : Endocarditis is related to infective endocarditis and brucellosis, and has symptoms including angina pectoris, edema and chest pain. An important gene associated with Endocarditis is CRP (C-Reactive Protein), and among its related pathways/superpathways are Innate Immune System and Toll-like Receptor Signaling Pathway. The drugs Cefazolin and Dextrose USP and Rifampicin have been mentioned in the context of this disorder. Affiliated tissues include heart, skin and lung, and related phenotypes are Reduced mammosphere formation and hematopoietic system

Disease Ontology : ¹² A endocardium disease characterized by inflammation of the endocardium of the heart chambers and valves.

PubMed Health : ⁶³ About endocarditis: Endocarditis (EN-do-kar-DI-tis) is an infection of the inner lining of the heart chambers and valves. This lining is called the endocardium (en-do-KAR-de-um). The condition also is called infective endocarditis (IE).The term "endocarditis" also is used to describe an inflammation of the endocardium due to other conditions. This article only discusses endocarditis related to infection.IE occurs if bacteria, fungi, or other germs invade your bloodstream and attach to abnormal areas of your heart. The infection can damage your heart and cause serious and sometimes fatal complications.IE can develop quickly or slowly; it depends on what type of germ is causing it and whether you have an underlying heart problem. When IE develops quickly, it's called acute infective endocarditis. When it develops slowly, it's called subacute infective endocarditis.

Wikipedia : ⁷⁶ Endocarditis is an inflammation of the inner layer of the heart, the endocardium. It usually involves... more...

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Related Diseases for Endocarditis

Diseases in the Endocarditis family:

Subacute Bacterial Endocarditis

Diseases related to Endocarditis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 740)

#	Related Disease	Score	Top Affiliating Genes
1	infective endocarditis	33.2	TNNI3 TNF TLR2 LBP IL6 FCGR2A
2	brucellosis	32.0	CRP CXCL8 IL10 IL6 TNF
3	rheumatic fever	30.8	IL10 IL6 TNF
4	q fever	30.7	IL10 IL6 TLR2 TNF
5	pericarditis	30.7	CRP IL6 TNF
6	endomyocardial fibrosis	30.5	IL10 TNF
7	arthritis	30.4	CXCL8 IL10 IL6 TNF
8	mycobacterium fortuitum	30.4	CXCL8 HSPD1 LACTB
9	lupus erythematosus	30.3	APOH FCGR2A IL10 TNF
10	patent foramen ovale	30.2	APOH F2 SERPINC1
11	antiphospholipid syndrome	30.2	APOH F2 SERPINC1 VCAM1
12	adult-onset still's disease	30.2	CRP IL6 TNF
13	disseminated intravascular coagulation	30.2	F2 PIK3C2A SERPINC1
14	pericardial effusion	30.2	CRP IL6 PIK3C2A
15	stroke, ischemic	30.2	APOH CRP F2 SERPINC1
16	septic arthritis	30.2	CRP CXCL8 TLR2
17	myocarditis	30.2	IL6 TNF TNNI3
18	rheumatic heart disease	30.1	IL10 IL6 TNF VCAM1
19	spondylitis	30.1	CRP IL6 TNF
20	microscopic polyangiitis	30.1	IL10 TNF
21	limb ischemia	30.1	IL6 TNF TNNI3
22	osteomyelitis	30.1	CXCL8 IL10 IL6 TNF
23	cardiogenic shock	30.1	IL6 PIK3C2A TNF
24	temporal arteritis	30.1	APOH CRP IL6 TNF
25	pulmonary embolism	30.1	ALB APOH CRP F2 SERPINC1 TNNI3
26	ischemic heart disease	30.1	TNF IL6 CRP
27	vasculitis	30.0	VCAM1 TNF CRP APOH
28	purpura	30.0	APOH CRP F2 IL6 SERPINC1 TNF
29	mycobacterium chelonae	30.0	CXCL8 TLR2
30	aspergillosis	30.0	IL10 TLR2 TNF
31	kawasaki disease	30.0	ALB CRP FCGR2A HSPD1 IL10 IL6
32	end stage renal failure	29.9	ALB CRP IL6 TNF
33	acute myocardial infarction	29.9	CRP PIK3C2A SERPINC1 TNNI3
34	heparin-induced thrombocytopenia	29.9	FCGR2A SERPINC1
35	trench fever	29.8	TLR2 TNF
36	fasciitis	29.8	CXCL8 IL6 TNF
37	sudden sensorineural hearing loss	29.8	APOH F2 IL6
38	acute cystitis	29.8	ALB CRP CXCL8 IL6
39	mycobacterium abscessus	29.8	TNF TLR2 CXCL8
40	protein s deficiency	29.8	APOH F2 SERPINC1
41	heart disease	29.7	ALB CRP CXCL8 F2 IL10 IL6
42	myocardial infarction	29.7	ALB CRP F2 IL10 IL6 PIK3C2A
43	thrombophlebitis	29.7	SERPINC1 F2 APOH
44	meningitis	29.7	TNF TLR2 LACTB IL6 IL10 FCGR2A
45	bacterial pneumonia	29.7	CRP CXCL8 IL6 LACTB
46	complex regional pain syndrome	29.7	IL10 IL6 TNF
47	polyarteritis nodosa	29.6	APOH CRP IL6
48	myeloma, multiple	29.6	ALB CRP CXCL8 IL6 TNF
49	colitis	29.6	CXCL8 IL10 IL6 TNF
50	haemophilus influenzae	29.6	CXCL8 TLR2 TNF

Graphical network of the top 20 diseases related to Endocarditis:

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Symptoms & Phenotypes for Endocarditis

UMLS symptoms related to Endocarditis:

angina pectoris, edema, chest pain

GenomeRNAi Phenotypes related to Endocarditis according to GeneCards Suite gene sharing:

²⁶

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Reduced mammosphere formation	GR00396-S	9.17	ALB CXCL8 FCGR2A HSPD1 PIK3C2A SERPINC1

MGI Mouse Phenotypes related to Endocarditis:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	hematopoietic system	MP:0005397	10.1	AQP9 EPX F2 FCGR2A IL10 IL6
2	cardiovascular system	MP:0005385	10.07	CRP F2 IL10 IL6 PIK3C2A SERPINC1
3	homeostasis/metabolism	MP:0005376	10.07	ALB APOH AQP9 CRP F2 IL10
4	immune system	MP:0005387	9.97	AQP9 CRP EPX F2 FCGR2A IL10
5	liver/biliary system	MP:0005370	9.5	ALB IL10 IL6 LBP SERPINC1 TLR2
6	mortality/aging	MP:0010768	9.44	ALB APOH F2 FCGR2A HSPD1 IL10

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Drugs & Therapeutics for Endocarditis

PubMedHealth treatment related to Endocarditis: ⁶³

Infective endocarditis (IE) is treated with antibiotics and sometimes with heart surgery.

FDA approved drugs:

#	Drug Name	Active Ingredient(s) ¹⁸	Company	Approval Date
1	Cefazolin and Dextrose USP ¹⁸	CEFAZOLIN SODIUM	B Braun Medical	July 2000
FDA Label: Cefazolin and Dextrose USP Disease/s that Drug Treats:Various bacterial infections, septicemia, endocarditis, and perioperative prophylaxis Indications and Usage: ¹⁸ Cefazolin for Injection USP and Dextrose Injection USP is a cephalosporin antibacterial indicated in the treatment of the following infections caused by susceptible isolates of the designated microorganisms: Respiratory tract infections (1.1); urinary tract infections (1.2); skin and skin structure infections (1.3); biliary tract infections (1.4); bone and joint infections (1.5); genital infections (1.6); septicemia (1.7); endocarditis (1.8) and perioperative prophylaxis (1.9). DrugBank Targets: ¹⁶ Penicillin-binding protein 1A\|Penicillin-binding protein 1B\|Penicillin-binding protein 1C\|Penicillin-binding protein 2 Mechanism of Action: ¹⁸ Target: - Action: - FDA: Cefazolin is an antibacterial drug [see Microbiology (12.4)]. Cefazolin is a bactericidal agent that acts by inhibition of bacterial cell wall synthesis.

Drugs for Endocarditis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 237)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Rifampicin

Approved

Phase 4,Phase 3

13292-46-1

5458213 5381226

Vancomycin

Approved

Phase 4,Phase 3,Phase 2,Not Applicable

1404-90-6

14969 441141

Lidocaine

Approved, Vet_approved

Phase 4,Phase 2

137-58-6

3676

Daptomycin

Approved, Investigational

Phase 4,Phase 3,Phase 2,Not Applicable

103060-53-3

16129629

Fosfomycin

Approved

Phase 4

23155-02-4

446987

Imipenem

Approved

Phase 4

74431-23-5, 64221-86-9

104838

Hexetidine

Approved, Investigational

Phase 4

141-94-6

Epinephrine

Approved, Vet_approved

Phase 4

51-43-4

5816

Racepinephrine

Approved

Phase 4

329-65-7

838

Chlorhexidine

Approved, Vet_approved

Phase 4,Not Applicable

55-56-1

2713 9552079

Amoxicillin

Approved, Vet_approved

Phase 4,Phase 3,Phase 2

26787-78-0

33613

Warfarin

Approved

Phase 4,Not Applicable

81-81-2

6691 54678486

Cephalexin

Approved, Investigational, Vet_approved

Phase 4,Phase 2,Phase 3

15686-71-2

27447

Apixaban

Approved

Phase 4,Not Applicable

503612-47-3

10182969

Edoxaban

Approved

Phase 4,Not Applicable

480449-70-5

Aspirin

Approved, Vet_approved

Phase 4,Not Applicable

50-78-2

2244

Phenprocoumon

Approved, Investigational

Phase 4

435-97-2

54680692 9908

Rivaroxaban

Approved

Phase 4,Not Applicable

366789-02-8

Clopidogrel

Approved

Phase 4,Not Applicable

113665-84-2, 120202-66-6

60606

Linezolid

Approved, Investigational

Phase 4,Phase 3

165800-03-3

441401

Serine

Approved, Nutraceutical

Phase 4,Not Applicable

56-45-1

5951

Antibiotics, Antitubercular

Phase 4,Phase 2,Phase 3,Not Applicable

Anti-Bacterial Agents

Phase 4,Phase 3,Phase 2,Not Applicable

Anti-Infective Agents

Phase 4,Phase 3,Phase 2,Not Applicable

methicillin

Phase 4,Phase 3,Phase 2

Antitubercular Agents

Phase 4,Phase 3,Phase 2,Not Applicable

Anesthetics

Phase 4,Phase 3,Phase 2,Not Applicable

Anti-Arrhythmia Agents

Phase 4,Phase 2

Peripheral Nervous System Agents

Phase 4,Phase 3,Phase 2,Not Applicable

Anesthetics, Local

Phase 4,Phase 2

Central Nervous System Depressants

Phase 4,Phase 2,Not Applicable

Diuretics, Potassium Sparing

Phase 4,Phase 2

Sodium Channel Blockers

Phase 4,Phase 2

Anti-Inflammatory Agents

Phase 4,Phase 3,Phase 2,Not Applicable

Analgesics, Non-Narcotic

Phase 4,Phase 2,Not Applicable

Anti-Inflammatory Agents, Non-Steroidal

Phase 4,Phase 2,Not Applicable

Cyclooxygenase Inhibitors

Phase 4,Phase 2,Not Applicable

Antirheumatic Agents

Phase 4,Phase 2,Not Applicable

Analgesics

Phase 4,Phase 2,Not Applicable

beta-Lactams

Phase 4

Lactams

Phase 4

Vasoconstrictor Agents

Phase 4

Pharmaceutical Solutions

Phase 4

Adrenergic alpha-Agonists

Phase 4,Not Applicable

Adrenergic beta-Agonists

Phase 4

Chlorhexidine gluconate

Phase 4,Not Applicable

Anti-Asthmatic Agents

Phase 4,Phase 3

Disinfectants

Phase 4,Not Applicable

Adrenergic Agents

Phase 4,Not Applicable

Mydriatics

Phase 4

Interventional clinical trials:

(show top 50) (show all 234)

#	Name	Status	NCT ID	Phase	Drugs
1	Rationale, Design and Methods for the Early Surgery in Infective Endocarditis Study (ENDOVAL)	Unknown status	NCT00624091	Phase 4
2	Pharmacokinetics/ Pharmacodynamics (PK/PD) Study of Vancomycin	Unknown status	NCT02443064	Phase 4	Vancomycin
3	Duration of Antibiotic Therapy in Community - Acquired Pneumonia	Unknown status	NCT01492387	Phase 4
4	Partial Oral Treatment of Endocarditis	Completed	NCT01375257	Phase 4	Oral treatment with antibiotics for endocarditis;Guideline treatment with parenteral antibiotics
5	Early Surgery Versus Conventional Treatment in Infective Endocarditis	Completed	NCT00750373	Phase 4
6	Fosfomycin Plus Imipenem for Treatment of Infective Endocarditis	Completed	NCT00871104	Phase 4	Fosfomycin and imipenem;Vancomycin
7	The Effect of Sodium Bicarbonate on Postoperative Renal Function in Infective Endocarditis Patients Undergoing Open Heart Surgery	Completed	NCT01920126	Phase 4	sodium bicarbonate;Saline
8	Diagnosis of Septicaemia by Detection of Microbial DNA in Blood in Severe Infections	Completed	NCT00709358	Phase 4
9	Bacteraemia Secondary to Tooth Extraction: Chlorhexidine Prophylaxis Protocols	Completed	NCT02150031	Phase 4	0.2% Chlorhexidine;1% Chlorhexidine;1% Chlorhexidine;Lidocaine plus adrenaline
10	Bacteremia in Periodontal Patients	Completed	NCT02215473	Phase 4	Chlorhexidine gluconate mouth rinse
11	World-wide Randomized Antibiotic Envelope Infection Prevention Trial	Completed	NCT02277990	Phase 4
12	The Value of 99mTc-Leukoscan® Scintigraphy in the Diagnosis of Infectious Endocarditis on Surgical Materials	Recruiting	NCT03112356	Phase 4	99mTc-Leukoscan® scintigraphy
13	An Oral Amoxicillin-Clavulanate Regimen to Prevent Bacteremia Following Dental Procedures	Recruiting	NCT02783404	Phase 4	Amoxicillin;Amoxicillin-Potassium Clavulanate
14	Daptomycin as Adjunctive Therapy for Staphylococcus Aureus Bacteremia	Recruiting	NCT02972983	Phase 4	Daptomycin
15	Left Atrial Appendage CLOSURE in Patients With Atrial Fibrillation Compared to Medical Therapy	Recruiting	NCT03463317	Phase 4	Acetylsalicylic acid;Clopidogrel;Dabigatran;Rivaroxaban;Apixaban;Edoxaban;Phenprocoumon;Warfarin
16	Oritavancin for Staphylococcus Aureus Infections in Opioid Users	Not yet recruiting	NCT03761953	Phase 4	Oritavancin Injection
17	Impact of Antibiotic Treatment Following Implantation of Cardiac Electronic Device on Patient's Outcome	Not yet recruiting	NCT03148444	Phase 4	cefalexin 500 mg qid or roxithromycin 150 mg bid
18	Daptomycin as an Adjuvant Agent in the Treatment of Enterococcal Native Valve Endocarditis.	Terminated	NCT00401960	Phase 4	Daptomycin
19	Phase 4 Efficacy and Safety Study of Cubicin® With and Without Combination Therapy in S. Aureus Infective Endocarditis (SAIE)	Terminated	NCT00638157	Phase 4	daptomycin;daptomycin and gentamicin
20	Safety and Efficacy of Strategy to Prevent Drug-Induced Nephrotoxicity in High-Risk Patients	Terminated	NCT01734694	Phase 4	Vancomycin;Ceftaroline;Daptomycin;Linezolid
21	The Role of Synbiotics in Reducing Post-Operative Infections in Patients Undergoing Cardiac Surgery: A Pilot Study	Terminated	NCT00164099	Phase 4	Synbiotic 2000
22	TRANscatheter or SurgIcal Aortic Valve ReplacemenT in All-Comers With Severe Aortic Valve Stenosis	Withdrawn	NCT02838199	Phase 4
23	Safety and Effectiveness Study of Perceval S Valve for Extended CE Mark	Unknown status	NCT01368666	Phase 2, Phase 3
24	Efficacy and Safety of Venus P-valve to Treat RVOT Stenosis With Pulmonary Regurgitation	Unknown status	NCT02071654	Phase 3
25	Minimally Invasive Transthoracic Device Closure in Perimembranous Ventricular Septal Defect	Unknown status	NCT02644330	Phase 2, Phase 3
26	Multi-center Trial of Percutaneous Pulmonary Valve Implantation With Venus-p	Unknown status	NCT02590679	Phase 2, Phase 3
27	Daptomycin in the Treatment of Subjects With Infective Endocarditis or Bacteremia Due to S. Aureus	Completed	NCT00093067	Phase 3	daptomycin
28	A Study of MK-3009 in Japanese Patients With Skin or Blood Stream Infections Caused by Methicillin-resistant Staphylococcus Aureus (MK-3009-002)	Completed	NCT00770341	Phase 3	Daptomycin 4 mg/kg;Comparator: vancomycin;Daptomycin 6 mg/kg
29	Population Pharmacokinetic (PK) Study of Multiple Doses of Cubicin® (Daptomycin) 10 mg/kg in Critical Care Patients Having Bacteremia, Endocarditis or Skin Soft Tissue Infections Due to Gram Positive Bacteria With Various Degrees of Renal Failure	Completed	NCT02142075	Phase 3	Daptomycin
30	Conservative Aortic Valve Surgery for Aortic Insufficiency and Aneurysms of the Aortic Root. CAVIAAR	Completed	NCT00478803	Phase 3
31	Early Antiretroviral Treatment and/or Early Isoniazid Prophylaxis Against Tuberculosis in HIV-infected Adults (ANRS 12136 TEMPRANO)	Completed	NCT00495651	Phase 3	Antiretroviral medications;Antiretroviral medications+Isoniazid prophylaxis;Antiretroviral medications;Antiretroviral medications+Isoniazid prophylaxis
32	Strategies Using Off-Patent Antibiotics for Methicillin Resistant S. Aureus "STOP MRSA"	Completed	NCT00729937	Phase 2, Phase 3	Cephalexin;Clindamycin;Trimethoprim-sulfamethoxazole
33	Oral Switch During Treatment of Left-sided Endocarditis Due to Multi-susceptible Streptococcus	Recruiting	NCT02701595	Phase 3	Amoxicillin
34	Oral Switch During Treatment of Left-sided Endocarditis Due to Multi-susceptible Staphylococcus	Recruiting	NCT02701608	Phase 3	Levofloxacin;Rifampicin
35	Ceftobiprole in the Treatment of Patients With Staphylococcus Aureus Bacteremia	Recruiting	NCT03138733	Phase 3	Ceftobiprole medocaril;Daptomycin
36	Staphylococcus Aureus Bacteremia Antibiotic Treatment Options	Recruiting	NCT01792804	Phase 3	Trimethoprim-Sulfamethoxazole;Clindamycin;Linezolid;Flucloxacillin;Cloxacillin;Vancomycin;Daptomycin;Cefazolin
37	Transfer Factor Efficacy in the Management of Cirrhosis-associated Immune Dysfunction	Recruiting	NCT02837939	Phase 2, Phase 3	Human derived Transfer factor;Aqua pro injectione 4ml ampules for subcutaneous injection
38	STeroids to REduce Systemic Inflammation After Neonatal Heart Surgery	Recruiting	NCT03229538	Phase 3	Methylprednisolone;Isotonic saline
39	Effect of Nitric Oxide in Cardiac Surgery Patients With Endothelial Dysfunction.	Recruiting	NCT02836899	Phase 3	Nitric Oxide
40	A Phase 3 Telavancin Staphylococcus Aureus (S. Aureus) Bacteremia Trial	Terminated	NCT02208063	Phase 3	Telavancin;Vancomycin;Daptomycin;Synthetic penicillin;Cefazolin
41	Linezolid in the Treatment of Hemodialysis Patients With Catheter-Related Gram-Positive Bloodstream Infections	Terminated	NCT00108433	Phase 3	Cefazolin IV;Linezolid IV;Vancomycin (IV)
42	Perioperative Ketorolac-lidocaine in the Patients With Valvular Heart Diseases During Cesarean Delivery	Unknown status	NCT01571791	Phase 2	Placebo;Ketorolac-Lidocaine
43	TranScatheter Aortic Valve RepLacement System US Feasibility Trial	Unknown status	NCT01932099	Phase 2
44	Bacteria Entering the Blood Stream From Tooth Extractions and Tooth Brushing	Completed	NCT00454285	Phase 2	Effect of Amoxicillin on bacteremia following a single-tooth extraction
45	Safety Evaluation of a Q-fever Vaccine, NDBR 105	Completed	NCT00584454	Phase 2
46	Feasibility Study of a Percutaneous Mitral Valve Repair System.	Completed	NCT00209339	Phase 1, Phase 2
47	Assessment of Radiolabeled rhAnnexin V-128 in Infective Endocarditis	Recruiting	NCT02459613	Phase 1, Phase 2
48	Neonatal Vancomycin Trial	Recruiting	NCT02790996	Phase 2	Vancomycin
49	Surgical Implantation of TRAnscatheter vaLve in Native Mitral Annular Calcification (SITRAL) Study	Recruiting	NCT02830204	Phase 1, Phase 2
50	Evaluation of an Antibiotic Regimen Pharmacokinetic Applicable to Enterococcus Faecalis Infective Endocarditis	Active, not recruiting	NCT03681431	Phase 2	Ceftriaxone 4g/ 24h;Ceftriaxone 2g/ 12h

Search NIH Clinical Center for Endocarditis

Inferred drug relations via UMLS ⁷³ / NDF-RT ⁵¹ :

gentamicin sulfate pwdr

Cochrane evidence based reviews: endocarditis

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Genetic Tests for Endocarditis

Sources

Anatomical Context for Endocarditis

MalaCards organs/tissues related to Endocarditis:

⁴¹

Heart, Skin, Lung, Testes, Kidney, Liver, Brain

Sources

Publications for Endocarditis

Articles related to Endocarditis:

(show top 50) (show all 4020)

#	Title	Authors	Year
1	Imaging the itis: endocarditis, myocarditis, and pericarditis. ( 30444758 )	O'Connor MJ	2019
2	Human native endocarditis caused by Streptococcus canis-a case report. ( 30549135 )	Mali?ov? B...Freiberger T	2019
3	Pericardial effusion in infective endocarditis: The times they are a-changin'. ( 30301562 )	Tattevin P...Donal E	2019
4	Prosthetic valve endocarditis - A trouble or a challenge? ( 30389305 )	Ivanovic B...Tadic M	2019
5	Aspergillus endocarditis diagnosed by fungemia plus serum antigen testing. ( 30416954 )	Hatlen TJ...Van TT	2019
6	Fasciitis in a Boy with Kingella Kingae Infective Endocarditis. ( 29870103 )	Al Yazidi L.S....Kesson A.	2018
7	Candida catenulata Candidaemia and Possible Endocarditis in a Cirrhotic Patient Successfully De-escalated to Oral Fluconazole. ( 29956355 )	Ha M.V....Suh J.S.	2018
8	Comparison of Dual I^-Lactam Therapy to Penicillin-Aminoglycoside Combination in Treatment of Enterococcus faecalis Infective Endocarditis. ( 29969596 )	Rafei A.E....Baddour L.M.	2018
9	Efficacy and Safety of Fosfomycin Plus Imipenem vs. Vancomycin for Complicated Bacteremia and Endocarditis Due to Methicillin-Resistant Staphylococcus aureus: A Randomized Clinical Trial. ( 29408610 )	PericA s J.M....Galvez J.	2018
10	Right-sided infective mural endocarditis complicated by septic pulmonary embolism and cardiac tamponade caused by MSSA. ( 29803298 )	Wu W....Chen G.H.	2018
11	Sneddon syndrome and non-bacterial thrombotic endocarditis: a clinicopathological study. ( 29980854 )	Berciano J....TerA!n-VillagrA! N.	2018
12	The diagnosis of microorganism involved in infective endocarditis (IE) by polymerase chain reaction (PCR) and real-time PCR: A systematic review. ( 29413230 )	Faraji R....Sarebanhassanabadi M.	2018
13	FISH and PNA FISH for the diagnosis of Q fever endocarditis and vascular infections. ( 29899006 )	Prudent E....Raoult D.	2018
14	A challenging case of carbapenemase-producing Klebsiella pneumoniae septic thrombophlebitis and right mural endocarditis successfully treated with ceftazidime/avibactam. ( 29926399 )	Iacovelli A....Venditti M.	2018
15	Case of infective endocarditis caused by implanted artificial hair pyoderma. ( 29923626 )	Arai S....Tsuruta D.	2018
16	Nonbacterial thrombotic endocarditis in a patient with primary antiphospholipid syndrome. ( 29977578 )	Sirinvaravong N....Rubin A.	2018
17	Prognostic implications of a negative echocardiography in patients with infective endocarditis. ( 29409744 )	Vicent L....MartA-nez-SellAcs M.	2018
18	Changes in the Association of Rising Infective Endocarditis With Mortality in People Who Inject Drugs. ( 29926083 )	Njoroge L.W....Oliveira G.H.	2018
19	A broad-range PCR technique for the diagnosis of infective endocarditis. ( 29429763 )	Boujelben I....Hammami A.	2018
20	Nonbacterial Thrombotic Endocarditis Presenting with Leg Pain and a Left Atrial Mass Lesion. ( 29448257 )	Abouarab A.A....Salemi A.	2018
21	Endocarditis. ( 29971399 )	Chu V.H.	2018
22	Acquired ventricular septal defect due to infective endocarditis. ( 29440841 )	Durden R.E....Bansal M.	2018
23	Endocarditis after transcatheter aortic valve implantation: a current assessment. ( 29434627 )	Chourdakis E....Hauptmann K.E.	2018
24	Primary Cardiac B-Non-Hodgkin Lymphoma Disguised as a Pacemaker Endocarditis. ( 29977733 )	FleiA9ner F....KA1hn C.	2018
25	Hemolytic anemia due to native valve subacute endocarditis with<i>Actinomyces israelii</i>infection. ( 29445480 )	Toom S....Xu Y.	2018
26	A rare case of paradoxical embolism from tricuspid valve infective endocarditis and patent foramen ovale. ( 29372516 )	Fong K.M....Lai K.Y.	2018
27	Rare presentation of Candida albicans: infective endocarditis and a pulmonary coin lesion. ( 29513204 )	A9ner T....A8elebi A.	2018
28	Risk Stratification and Optimization of Cardiac Surgical Patients With Infective Endocarditis: Does It Matter? ( 29929896 )	Stein E....Andritsos M.	2018
29	Bioprosthetic Versus Mechanical Valve Replacement for Infective Endocarditis: Focus on Recurrence Rates. ( 29452115 )	Toyoda N....Chikwe J.	2018
30	Necrotizing Crescentic Glomerulonephritis Complicating Bivalvular Bacterial Endocarditis. ( 29942723 )	Hashmi A.T....Kamholz S.	2018
31	Mitral valve repair versus replacement for infective endocarditis. What is better in the &quot;real world&quot;? ( 29958668 )	Antunes M.J.	2018
32	Both-sided native valve infective endocarditis in a drug addict with incidental pneumoconiosis. ( 29704724 )	Tyagi S....Meshram V.	2018
33	Loeffler endocarditis as a rare cause of heart failure with preserved ejection fraction: A case report and review of literature. ( 29538200 )	Gao M....Zheng Y.	2018
34	Probiotics and infective endocarditis in patients with hereditary hemorrhagic telangiectasia: a clinical case and a review of the literature. ( 29390976 )	Boumis E....Petrosillo N.	2018
35	Emphysematous endocarditis caused by AmpC beta-lactamase-producing Escherichia coli: A case report. ( 29419663 )	Kim C.J....Choi H.J.	2018
36	Bilateral septic arthritis of the sternoclavicular joint complicating infective endocarditis: a case report. ( 29973288 )	Masmoudi K....Baklouti S.	2018
37	Infective endocarditis in a patient with metastatic colorectal cancer. ( 29390605 )	Callejo-Goena A....LA^pez-Vivanco G.	2018
38	Outcomes of Reoperative Valve Replacement in Patients with Prosthetic Valve Endocarditis: A 20-Year Experience. ( 29430424 )	Kim Y.W....Kim J.B.	2018
39	Infective endocarditis associated with <i>Bartonella henselae</i>: A case series. ( 29942769 )	Nakasu A....Mototake H.	2018
40	Manuscript title: Cardiac and neurological involvement in Antiphospholipid syndrome: a case of a 47-year-old woman with nonbacterial thrombotic endocarditis and cognitive impairment. ( 29936322 )	Papaliagkas V....Hatzitolios I.A.	2018
41	Endocarditis associated with vertebral osteomyelitis and septic arthritis of the axial skeleton. ( 29396671 )	Murillo O....Pallares R.	2018
42	Marantic endocarditis: incidental infarcts leading to diagnosis of pancreatic cancer. ( 29895577 )	Starobinska E....Scott S.	2018
43	Lessons learned from splenic infarcts with fever of unknown origin (FUO): culture-negative endocarditis (CNE) or malignancy? ( 29417312 )	Cunha B.A....Varantsova A.	2018
44	Infective Endocarditis Associated with Atrial Septal Defect in an Intravenous Drug Abuser: A Case Report. ( 29922523 )	Jahangir M....Hasnain N.	2018
45	A pragmatic approach for mortality prediction after surgery in infective endocarditis: Optimizing and refining EuroSCORE. ( 29408350 )	FernA!ndez-Hidalgo N....Almirante B.	2018
46	<i>Staphylococcus aureus</i> CC30 Lineage and Absence of <i>sed</i>,<i>j</i>,<i>r</i>-Harboring Plasmid Predict Embolism in Infective Endocarditis. ( 29938201 )	Rasigade J.P....Leport C.	2018
47	Utility of cardiac computed tomography scanning in the diagnosis and pre-operative evaluation of patients with infective endocarditis. ( 29450741 )	Sims J.R....DeSimone D.C.	2018
48	Marseille scoring system for empiric treatment of infective endocarditis. ( 29397446 )	Gouriet F....Raoult D.	2018
49	Endophthalmitis and Mycotic Aneurysm: The Only Clues to Underlying Endocarditis. ( 29849250 )	Carmelli G....Brown A.	2018
50	Gemella bergeri infective endocarditis: a case report and brief review of literature. ( 29444729 )	Zaidi S.J....Collins M.A.	2018

Sources

Genes for Endocarditis

Genes related to Endocarditis (0 elite genes):

(show all 21)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	CRP	C-Reactive Protein	Protein Coding	23.52	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
2	F2	Coagulation Factor II, Thrombin	Protein Coding	22.31	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
3	EPX	Eosinophil Peroxidase	Protein Coding	21.93	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵ GeneCards inferred via : Publications (show sections)	1985118 2002037
4	TNF	Tumor Necrosis Factor	Protein Coding	21.75	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
5	HSPD1	Heat Shock Protein Family D (Hsp60) Member 1	Protein Coding	21.56	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
6	ALB	Albumin	Protein Coding	21.56	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
7	LBP	Lipopolysaccharide Binding Protein	Protein Coding	21.23	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
8	IL6	Interleukin 6	Protein Coding	21.12	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
9	PIK3C2A	Phosphatidylinositol-4-Phosphate 3-Kinase Catalytic Subunit Type 2 Alpha	Protein Coding	21.07	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
10	CXCL8	C-X-C Motif Chemokine Ligand 8	Protein Coding	21	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
11	TNNI3	Troponin I3, Cardiac Type	Protein Coding	20.99	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
12	FCGR2A	Fc Fragment Of IgG Receptor IIa	Protein Coding	20.94	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
13	APOH	Apolipoprotein H	Protein Coding	20.87	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
14	SERPINC1	Serpin Family C Member 1	Protein Coding	20.54	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
15	VCAM1	Vascular Cell Adhesion Molecule 1	Protein Coding	20.48	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
16	IL10	Interleukin 10	Protein Coding	20.39	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
17	TLR2	Toll Like Receptor 2	Protein Coding	20.35	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
18	LACTB	Lactamase Beta	Protein Coding	12.14	Novoseek inferred ⁵⁵ GeneCards inferred via : Publications (show sections)	8323254 1389104 2050588 (more) 8444668
19	CEACAM8	Carcinoembryonic Antigen Related Cell Adhesion Molecule 8	Protein Coding	11.17	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
20	AQP9	Aquaporin 9	Protein Coding	10.74	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
21	PLAT	Plasminogen Activator, Tissue Type	Protein Coding	10.18	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)

Sources

Variations for Endocarditis

Sources

Expression for Endocarditis

Search GEO for disease gene expression data for Endocarditis.

Sources

Pathways for Endocarditis

Pathways related to Endocarditis according to GeneCards Suite gene sharing:

(show all 37)

#	Super pathways	Score	Top Affiliating Genes
1	Innate Immune System ⁶⁶ Show member pathways Immune System ⁶⁶ Neutrophil degranulation ⁶⁶	14.01	CEACAM8 CRP CXCL8 EPX FCGR2A IL10
2	Toll-like Receptor Signaling Pathway ³⁷ ¹ Show member pathways Chagas disease (American trypanosomiasis) ³⁷ NOD-like receptor signaling pathway ³⁷ NOD-like Receptor Signaling Pathways ⁶⁵ Regulation of toll-like receptor signaling pathway ¹	12.97	CXCL8 IL10 IL6 LBP TLR2 TNF
3	Allograft rejection ¹ ³⁷ Show member pathways Antigen processing and presentation ³⁷ Asthma ³⁷ Autoimmune thyroid disease ³⁷ CTL Mediated Apoptosis ⁶⁴ Graft-versus-host disease ³⁷ Intestinal immune network for IgA production ³⁷ THC Differentiation Pathway ⁶⁴ Type I diabetes mellitus ³⁷ Viral myocarditis ³⁷	12.84	CXCL8 EPX HSPD1 IL10 IL6 TNF
4	IL-17 Family Signaling Pathways ⁶⁵ Show member pathways IL17 signaling pathway ¹ IL-17 signaling pathway ³⁷ Interleukin-17 signaling ⁶⁶ Mucin expression in CF via IL-6, IL-17 signaling pathways ²²	12.29	CXCL8 IL6 TLR2 TNF
5	Selenium Micronutrient Network ¹ Show member pathways Folate Metabolism ¹ Metabolism of ingested MeSeO2H into MeSeH ⁶⁶ thioredoxin pathway ¹ Vitamin B12 Metabolism ¹	12.29	ALB CRP F2 IL6 TNF
6	Toll Comparative Pathway ⁶⁴ Show member pathways IL-1 Pathway ⁶⁴ Immune response MIF in innate immunity response ²² iNOS Signaling ⁶⁴ TLR-TRIF Pathway ⁶⁴	12.26	CXCL8 IL6 LBP TNF
7	Diseases associated with the TLR signaling cascade ⁶⁶ Show member pathways Diseases of Immune System ⁶⁶ Interleukin-1 Induced Activation of NF-kappa-B ¹ IRAK1 recruits IKK complex ⁶⁶ IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation ⁶⁶ IRAK4 deficiency (TLR2/4) ⁶⁶ IRAK4 deficiency (TLR5) ⁶⁶ MyD88 deficiency (TLR2/4) ⁶⁶ MyD88 deficiency (TLR5) ⁶⁶ Simplified Depiction of MYD88 Distinct Input-Output Pathway ¹ TLR4 Signaling and Tolerance ¹ Toll-like Receptor Signaling ¹	12.23	CXCL8 IL6 TLR2 TNF
8	Toxoplasmosis ³⁷ Show member pathways Leishmaniasis ³⁷	12.22	FCGR2A IL10 TLR2 TNF
9	IL-1 Family Signaling Pathways ⁶⁵ Show member pathways Immune response IL-1 signaling pathway ²² Mucin expression in CF via TLRs, EGFR signaling pathways ²²	12.17	CXCL8 IL6 TLR2 TNF
10	Bacterial infections in CF airways ²² Show member pathways IL-1 beta-dependent CFTR expression ²² Immune response Bacterial infections in normal airways ²² Immune response TLR signaling pathways ²²	12.13	CXCL8 IL6 LBP TLR2 TNF
11	Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways ¹	12.1	CXCL8 HSPD1 IL10 IL6 TNF
12	Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers ⁶⁵	12.04	ALB IL6 TNNI3 VCAM1
13	Th1 Differentiation Pathway ⁶⁵ Show member pathways IL27-mediated signaling events ¹ Th17 Differentiation Pathway ⁶⁵	12.03	IL10 IL6 TLR2 TNF
14	Spinal Cord Injury ¹	11.98	CXCL8 FCGR2A IL6 TNF
15	Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers ⁶⁵	11.92	CEACAM8 FCGR2A IL10 IL6 TNF
16	AGE-RAGE signaling pathway in diabetic complications ³⁷	11.88	CXCL8 IL6 TNF VCAM1
17	NF-kappa B signaling pathway ³⁷	11.85	CXCL8 LBP TNF VCAM1
18	Microglia Activation During Neuroinflammation: Overview ⁶⁵ Show member pathways Microglia Activation During Neuroinflammation: Microglia Activation ⁶⁵	11.83	F2 FCGR2A HSPD1 IL6 TLR2 TNF
19	Rheumatoid arthritis ³⁷	11.82	CXCL8 IL6 TLR2 TNF
20	IL6-mediated signaling events ¹ Show member pathways IL-6 signaling pathway ¹	11.78	CRP IL6 LBP
21	Salmonella infection (KEGG) ³⁷	11.78	CXCL8 IL6 LBP
22	Amoebiasis ³⁷	11.78	CXCL8 IL10 IL6 TLR2 TNF
23	Tuberculosis ³⁷	11.75	FCGR2A HSPD1 IL10 IL6 LBP TLR2
24	Pertussis ³⁷	11.73	CXCL8 IL10 IL6 TNF
25	Dendritic Cells Developmental Lineage Pathway ⁶⁵	11.7	IL10 IL6 TNF
26	Microglia Activation During Neuroinflammation: Microglia Polarization ⁶⁵	11.69	FCGR2A IL10 IL6 TNF
27	Interleukin-4 and 13 signaling ⁶⁶	11.69	CXCL8 IL10 IL6 LBP TNF VCAM1
28	Lung fibrosis ¹	11.63	CXCL8 IL6 TNF
29	Photodynamic therapy-induced NF-kB survival signaling ¹ Show member pathways Immune response MIF-mediated glucocorticoid regulation ²²	11.62	CXCL8 IL6 TNF VCAM1
30	Interleukin-10 signaling ⁶⁶	11.47	CXCL8 IL10 IL6 TNF
31	Legionellosis ³⁷	11.46	CXCL8 HSPD1 IL6 TLR2 TNF
32	IL-10 Pathway ⁶⁴	11.33	IL10 IL6 TNF
33	African trypanosomiasis ³⁷	11.28	IL10 IL6 TNF VCAM1
34	Cytokines and Inflammatory Response ¹	11.23	IL10 IL6 TNF
35	G-protein signaling_RhoB regulation pathway ²²	11.16	CXCL8 IL10 IL6 TNF
36	Overview of nanoparticle effects ¹	10.95	CRP CXCL8 IL6 TNF
37	Malaria ³⁷	10.79	CXCL8 IL10 IL6 TLR2 TNF VCAM1

Sources

GO Terms for Endocarditis

Cellular components related to Endocarditis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	extracellular exosome	GO:0070062	9.96	ALB APOH CEACAM8 EPX F2 HSPD1
2	extracellular region	GO:0005576	9.9	ALB APOH CRP CXCL8 EPX F2
3	cell surface	GO:0009986	9.5	APOH CEACAM8 HSPD1 LBP TLR2 TNF
4	extracellular space	GO:0005615	9.47	ALB APOH CEACAM8 CRP CXCL8 EPX

Biological processes related to Endocarditis according to GeneCards Suite gene sharing:

(show all 30)

#	Name	GO ID	Score	Top Affiliating Genes
1	immune response	GO:0006955	9.95	AQP9 CEACAM8 CXCL8 IL10 IL6 TLR2
2	defense response to bacterium	GO:0042742	9.94	EPX IL10 LBP TNF
3	cellular protein metabolic process	GO:0044267	9.92	ALB F2 IL6 SERPINC1
4	response to lipopolysaccharide	GO:0032496	9.89	HSPD1 IL10 LBP TLR2 VCAM1
5	cellular response to lipopolysaccharide	GO:0071222	9.88	CXCL8 IL10 IL6 LBP TNF
6	response to organic substance	GO:0010033	9.86	AQP9 HSPD1 IL10 TNF
7	cytokine-mediated signaling pathway	GO:0019221	9.85	CXCL8 IL10 IL6 LBP TNF VCAM1
8	response to glucocorticoid	GO:0051384	9.83	HSPD1 IL10 IL6 TNF
9	positive regulation of inflammatory response	GO:0050729	9.81	HSPD1 TLR2 TNF
10	lipopolysaccharide-mediated signaling pathway	GO:0031663	9.76	LBP TLR2 TNF
11	positive regulation of interleukin-8 production	GO:0032757	9.74	LBP TLR2 TNF
12	positive regulation of macrophage activation	GO:0043032	9.71	HSPD1 IL10 LBP
13	negative regulation of growth of symbiont in host	GO:0044130	9.69	IL10 LBP TNF
14	positive regulation of blood coagulation	GO:0030194	9.65	APOH F2
15	cellular response to lipoteichoic acid	GO:0071223	9.63	LBP TLR2
16	negative regulation of fibrinolysis	GO:0051918	9.63	APOH F2
17	regulation of blood coagulation	GO:0030193	9.63	APOH F2 SERPINC1
18	opsonization	GO:0008228	9.62	CRP LBP
19	endothelial cell apoptotic process	GO:0072577	9.61	IL10 TNF
20	response to molecule of bacterial origin	GO:0002237	9.61	CXCL8 IL10 TLR2
21	negative regulation of cytokine secretion involved in immune response	GO:0002740	9.6	IL10 TNF
22	positive regulation of neuroinflammatory response	GO:0150078	9.59	IL6 TNF
23	receptor biosynthetic process	GO:0032800	9.58	IL10 TNF
24	acute-phase response	GO:0006953	9.56	CRP F2 IL6 LBP
25	defense response to Gram-positive bacterium	GO:0050830	9.55	CRP IL6 LBP TLR2 TNF
26	negative regulation of lipid storage	GO:0010888	9.5	CRP IL6 TNF
27	positive regulation of chemokine production	GO:0032722	9.26	IL6 LBP TLR2 TNF
28	positive regulation of interleukin-6 production	GO:0032755	9.02	HSPD1 IL6 LBP TLR2 TNF
29	inflammatory response	GO:0006954	10.02	CRP CXCL8 IL10 IL6 TLR2 TNF
30	regulation of signaling receptor activity	GO:0010469	10.01	CXCL8 F2 IL10 IL6 TNF

Molecular functions related to Endocarditis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	identical protein binding	GO:0042802	9.5	ALB APOH CRP LACTB SERPINC1 TLR2
2	cytokine activity	GO:0005125	9.46	CXCL8 IL10 IL6 TNF
3	lipopeptide binding	GO:0071723	9.26	LBP TLR2
4	lipopolysaccharide binding	GO:0001530	8.92	F2 HSPD1 LBP TLR2

Sources

Sources for Endocarditis

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ ExPASy

¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia

Endocarditis

Aliases & Classifications for Endocarditis

MalaCards integrated aliases for Endocarditis:

Classifications:

External Ids:

Summaries for Endocarditis

Related Diseases for Endocarditis

Diseases in the Endocarditis family:

Diseases related to Endocarditis via text searches within MalaCards or GeneCards Suite gene sharing:

Graphical network of the top 20 diseases related to Endocarditis:

Symptoms & Phenotypes for Endocarditis

UMLS symptoms related to Endocarditis:

GenomeRNAi Phenotypes related to Endocarditis according to GeneCards Suite gene sharing:

MGI Mouse Phenotypes related to Endocarditis:

Drugs & Therapeutics for Endocarditis

PubMedHealth treatment related to Endocarditis: 63

FDA approved drugs:

Drugs for Endocarditis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

Interventional clinical trials:

Inferred drug relations via UMLS 73 / NDF-RT 51 :

Cochrane evidence based reviews: endocarditis

Genetic Tests for Endocarditis

Anatomical Context for Endocarditis

MalaCards organs/tissues related to Endocarditis:

Publications for Endocarditis

Articles related to Endocarditis:

Genes for Endocarditis

Genes related to Endocarditis (0 elite genes):

Variations for Endocarditis

Expression for Endocarditis

Pathways for Endocarditis

Pathways related to Endocarditis according to GeneCards Suite gene sharing:

GO Terms for Endocarditis

Cellular components related to Endocarditis according to GeneCards Suite gene sharing:

Biological processes related to Endocarditis according to GeneCards Suite gene sharing:

Molecular functions related to Endocarditis according to GeneCards Suite gene sharing:

Sources for Endocarditis

PubMedHealth treatment related to Endocarditis: ⁶³

Inferred drug relations via UMLS ⁷³ / NDF-RT ⁵¹ :