MCID: END074
MIFTS: 22

Endocardium Disease

Categories: Cardiovascular diseases

Aliases & Classifications for Endocardium Disease

MalaCards integrated aliases for Endocardium Disease:

Name: Endocardium Disease 12 15
Abnormality of the Endocardium 29

Classifications:



External Ids:

Disease Ontology 12 DOID:0050825

Summaries for Endocardium Disease

Disease Ontology : 12 A heart disease that is located in the innermost layer of tissue that lines the chambers of the heart.

MalaCards based summary : Endocardium Disease, also known as abnormality of the endocardium, is related to endocarditis and ovarian squamous cell carcinoma. An important gene associated with Endocardium Disease is TAZ (Tafazzin). Affiliated tissues include the innermost layer of tissue and heart, and related phenotypes are cardiovascular system and cellular

Related Diseases for Endocardium Disease

Diseases related to Endocardium Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 162)
# Related Disease Score Top Affiliating Genes
1 endocarditis 31.5 CRP F2 HSPD1
2 ovarian squamous cell carcinoma 11.0 CRP SMUG1
3 cardiovascular syphilis 10.9 CD40LG SMUG1
4 tertiary syphilis 10.9 CD40LG SH3BP5
5 endocardial fibroelastosis 10.9
6 acalculous cholecystitis 10.9 CD40LG CRP
7 mononeuritis multiplex 10.9 CD40LG CRP
8 aortitis 10.9 CRP SMUG1
9 partial motor epilepsy 10.8 F3 SMUG1
10 bone epithelioid hemangioma 10.8 F3 SMUG1
11 selective igg deficiency disease 10.8 CD40LG CD79A
12 c1q nephropathy 10.8 CD40LG CD79A
13 meningovascular neurosyphilis 10.8 CD40LG CD79A
14 alpha chain disease 10.8 CD40LG CD79A
15 brill-zinsser disease 10.8 CD40LG CD79A
16 exudative glomerulonephritis 10.8 CD40LG CD79A
17 cork-handlers' disease 10.8 CD40LG CD79A
18 heparin-induced thrombocytopenia 10.8 CD40LG F3
19 salpingo-oophoritis 10.8 CD40LG CD79A
20 chorea gravidarum 10.8 DLL1 F3
21 early yaws 10.8 CD40LG CD79A
22 ventilation pneumonitis 10.8 CD40LG CD79A
23 intestinal tuberculosis 10.8 CD79A CRP
24 chronic interstitial cystitis 10.8 CD40LG CD79A
25 axillary adenitis 10.8 CD40LG CD79A
26 cryofibrinogenemia 10.8 CD40LG CD79A
27 trichostrongyloidiasis 10.8 CD40LG CD79A
28 subacute bacterial endocarditis 10.7 CD40LG CD79A
29 malignant otitis externa 10.7 CRP F2
30 heterophyiasis 10.7 CD40LG CD79A
31 immunoglobulin g deficiency 10.7 CD40LG CD79A
32 transient hypogammaglobulinemia of infancy 10.7 CD40LG CD79A
33 hyperglobulinemic purpura 10.7 CD40LG CD79A
34 gastroduodenitis 10.7 CD40LG CD79A
35 bacterial conjunctivitis 10.7 CD40LG CD79A
36 mediastinitis 10.7 CRP NKX2-6
37 heavy chain disease 10.7 CD40LG CD79A
38 central nervous system vasculitis 10.7 CD40LG CRP SMUG1
39 ophthalmia neonatorum 10.7 CD40LG CD79A
40 immunoglobulin a deficiency 1 10.7 CD40LG CD79A
41 parotid disease 10.7 CD40LG CD79A
42 cerebral arteritis 10.7 CD40LG CD79A
43 selective immunoglobulin deficiency disease 10.7 CD40LG CD79A
44 temporal arteritis 10.7 CD40LG CRP SMUG1
45 geniculate herpes zoster 10.7 CD40LG CD79A
46 erythema elevatum diutinum 10.7 CD40LG CD79A
47 sporotrichosis 10.6 CD40LG CD79A
48 lemierre's syndrome 10.6 CRP F3 SMUG1
49 chronic thromboembolic pulmonary hypertension 10.6 CRP F2
50 hyperimmunoglobulin syndrome 10.6 CD40LG CD79A

Graphical network of the top 20 diseases related to Endocardium Disease:



Diseases related to Endocardium Disease

Symptoms & Phenotypes for Endocardium Disease

MGI Mouse Phenotypes related to Endocardium Disease:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.9 F2 F3 MKL1 MTM1 NKX2-6 PRF1
2 cellular MP:0005384 9.73 DLL1 F3 HSPD1 MKL1 MTM1 NKX2-6
3 homeostasis/metabolism MP:0005376 9.36 DLL1 F2 F3 MKL1 MTM1 NKX2-6

Drugs & Therapeutics for Endocardium Disease

Search Clinical Trials , NIH Clinical Center for Endocardium Disease

Genetic Tests for Endocardium Disease

Genetic tests related to Endocardium Disease:

# Genetic test Affiliating Genes
1 Abnormality of the Endocardium 29

Anatomical Context for Endocardium Disease

The Foundational Model of Anatomy Ontology organs/tissues related to Endocardium Disease:

19
The Innermost Layer Of Tissue

MalaCards organs/tissues related to Endocardium Disease:

41
Heart

Publications for Endocardium Disease

Variations for Endocardium Disease

Expression for Endocardium Disease

Search GEO for disease gene expression data for Endocardium Disease.

Pathways for Endocardium Disease

GO Terms for Endocardium Disease

Cellular components related to Endocardium Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 membrane raft GO:0045121 8.92 CD79A DLL1 PRTN3 SERPINH1

Biological processes related to Endocardium Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein maturation GO:0051604 9.16 HSPD1 SERPINH1
2 positive regulation of skeletal muscle tissue growth GO:0048633 8.96 DLL1 MTM1
3 B cell proliferation GO:0042100 8.8 CD40LG CD79A HSPD1

Sources for Endocardium Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....