MCID: END074
MIFTS: 22

Endocardium Disease

Categories: Cardiovascular diseases

Aliases & Classifications for Endocardium Disease

MalaCards integrated aliases for Endocardium Disease:

Name: Endocardium Disease 12 15
Abnormality of the Endocardium 29

Classifications:



External Ids:

Disease Ontology 12 DOID:0050825

Summaries for Endocardium Disease

Disease Ontology : 12 A heart disease that is located in the innermost layer of tissue that lines the chambers of the heart.

MalaCards based summary : Endocardium Disease, also known as abnormality of the endocardium, is related to endocarditis and endocardial fibroelastosis. An important gene associated with Endocardium Disease is CRP (C-Reactive Protein), and among its related pathways/superpathways is Folate Metabolism. Affiliated tissues include innermost layer of tissue and heart, and related phenotypes are cardiovascular system and cellular

Related Diseases for Endocardium Disease

Diseases related to Endocardium Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 377)
# Related Disease Score Top Affiliating Genes
1 endocarditis 32.5 HSPD1 F2 CRP CAT ALB
2 endocardial fibroelastosis 11.2
3 orbital osteomyelitis 10.7 F2 CRP
4 small intestine diverticulitis 10.7 F2 CRP
5 chronic duodenal ileus 10.7 CRP ALB
6 non-a-e hepatitis 10.7 F2 ALB
7 antipyrine metabolism 10.7 F2 ALB
8 cryofibrinogenemia 10.7 FN1 CD40LG
9 cork-handlers' disease 10.7 CD40LG ALB
10 exudative glomerulonephritis 10.7 CFHR2 CD40LG
11 congenital rubella 10.7 CD40LG CAT
12 epiglottitis 10.7 SIGLEC5 CRP CD40LG
13 bacterial conjunctivitis 10.7 SIGLEC5 CRP CD40LG
14 retroperitoneal lymphoma 10.7 F2 CD40LG
15 orbital granuloma 10.7 PRTN3 CRP
16 heparin-induced thrombocytopenia 10.7 F3 CD40LG
17 hematocele of tunica vaginalis testis 10.7 F2 CRP
18 meningitis and encephalitis 10.7 CAT ALB
19 japanese spotted fever 10.7 CRP CD40LG
20 heterophyiasis 10.7 CD40LG ALB
21 lymphangitis 10.7 SIGLEC5 CRP ALB
22 meningovascular neurosyphilis 10.7 CRP CD40LG ALB
23 gastrointestinal tuberculosis 10.7 CRP CD40LG ALB
24 granulomatous hepatitis 10.7 CRP CD40LG ALB
25 klebsiella pneumonia 10.7 CRP CD40LG ALB
26 astrakhan spotted fever 10.7 F3 CD40LG
27 streptococcus pneumonia 10.7 SIGLEC5 CRP CD40LG
28 hydrops of gallbladder 10.7 CRP CD40LG ALB
29 fallopian tube disease 10.7 SIGLEC5 CRP CD40LG
30 achenbach syndrome 10.7 F3 F2 CRP
31 anterior scleritis 10.7 PRTN3 CRP
32 chronic orbital inflammation 10.7 PRTN3 CRP CD40LG
33 allergic cutaneous vasculitis 10.7 PRTN3 CD40LG
34 duodenitis 10.7 CRP CD40LG ALB
35 ascending cholangitis 10.7 F2 CRP ALB
36 chronic meningitis 10.7 CRP CD40LG ALB
37 parotitis 10.7 CRP CD40LG ALB
38 miliary tuberculosis 10.7 CRP CD40LG ALB
39 synovial angioma 10.7 F3 F2 CRP
40 renal pelvis squamous cell carcinoma 10.7 F3 F2 CRP
41 blue toe syndrome 10.7 F3 F2 CRP
42 papillary adenofibroma 10.7 F3 F2
43 emphysematous cholecystitis 10.7 F3 F2 CRP
44 mononeuritis of upper limb and mononeuritis multiplex 10.7 PRTN3 CRP CD40LG
45 mononeuritis multiplex 10.7 PRTN3 CRP CD40LG
46 cavernous sinus thrombosis 10.7 F3 F2 CRP
47 acute cholangitis 10.7 F2 CRP ALB
48 panuveitis 10.7 CRP CFHR2 CD40LG
49 lemierre's syndrome 10.7 F3 F2 CRP
50 marantic endocarditis 10.7 F3 F2 CRP

Graphical network of the top 20 diseases related to Endocardium Disease:



Diseases related to Endocardium Disease

Symptoms & Phenotypes for Endocardium Disease

MGI Mouse Phenotypes related to Endocardium Disease:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.7 ALB CD40LG CRP F2 F3 FN1
2 cellular MP:0005384 9.36 ALB CAT CD40LG ETV5 F2 F3

Drugs & Therapeutics for Endocardium Disease

Search Clinical Trials , NIH Clinical Center for Endocardium Disease

Genetic Tests for Endocardium Disease

Genetic tests related to Endocardium Disease:

# Genetic test Affiliating Genes
1 Abnormality of the Endocardium 29

Anatomical Context for Endocardium Disease

The Foundational Model of Anatomy Ontology organs/tissues related to Endocardium Disease:

19
Innermost Layer Of Tissue

MalaCards organs/tissues related to Endocardium Disease:

40
Heart

Publications for Endocardium Disease

Articles related to Endocardium Disease:

# Title Authors PMID Year
1
The fetal heart: a practical sonographic approach. 61
8845190 1996

Variations for Endocardium Disease

Expression for Endocardium Disease

Search GEO for disease gene expression data for Endocardium Disease.

Pathways for Endocardium Disease

Pathways related to Endocardium Disease according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.26 F2 CRP CAT ALB

GO Terms for Endocardium Disease

Cellular components related to Endocardium Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.7 PRTN3 PRF1 PLGLB2 FN1 F3 F2
2 collagen-containing extracellular matrix GO:0062023 9.55 SERPINH1 PRTN3 FN1 F3 F2
3 extracellular space GO:0005615 9.36 TST SERPINH1 PRTN3 HSPD1 FN1 F3

Biological processes related to Endocardium Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytolysis by host of symbiont cells GO:0051838 9.16 F2 CFHR2
2 interaction with symbiont GO:0051702 8.96 HSPD1 FN1
3 acute-phase response GO:0006953 8.8 FN1 F2 CRP

Molecular functions related to Endocardium Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 enzyme binding GO:0019899 9.35 PRTN3 PPP3CA HSPD1 FN1 CAT
2 serine-type endopeptidase activity GO:0004252 8.92 PRTN3 PLGLB2 F3 F2

Sources for Endocardium Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....