MCID: END039
MIFTS: 45

Endodermal Sinus Tumor

Categories: Cancer diseases, Liver diseases, Fetal diseases

Aliases & Classifications for Endodermal Sinus Tumor

MalaCards integrated aliases for Endodermal Sinus Tumor:

Name: Endodermal Sinus Tumor 12 44 15
Yolk Sac Tumor 12 76 55 73
Infantile Embryonal Carcinoma 12
Hepatoid Yolk Sac Tumour 12
Yolk Sac Neoplasm 12

Classifications:



External Ids:

Disease Ontology 12 DOID:1911
MeSH 44 D018240
NCIt 50 C3011
SNOMED-CT 68 404081005 74409009
UMLS 73 C0014145

Summaries for Endodermal Sinus Tumor

Disease Ontology : 12 A germ cell cancer that has material basis in cells that line the yolk sac of the embryo.

MalaCards based summary : Endodermal Sinus Tumor, also known as yolk sac tumor, is related to ovarian endodermal sinus tumor and testicular yolk sac tumor. An important gene associated with Endodermal Sinus Tumor is AFP (Alpha Fetoprotein), and among its related pathways/superpathways are Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers and FOXA1 transcription factor network. The drugs Bleomycin and Cisplatin have been mentioned in the context of this disorder. Affiliated tissues include ovary, bone and brain, and related phenotype is Reduced mammosphere formation.

Wikipedia : 76 Endodermal sinus tumor (EST), also known as yolk sac tumor (YST), is a member of the germ cell tumor... more...

Related Diseases for Endodermal Sinus Tumor

Diseases in the Endodermal Sinus Tumor family:

Adult Endodermal Sinus Tumor

Diseases related to Endodermal Sinus Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 168)
# Related Disease Score Top Affiliating Genes
1 ovarian endodermal sinus tumor 32.9 AFP KRT7 SALL4 SERPINA1
2 testicular yolk sac tumor 31.4 AFP ALB SALL4 SERPINA1
3 mixed germ cell tumor 31.3 AFP CGB3
4 mucinous cystadenofibroma 31.0 AFP SERPINA1
5 teratoma 30.8 AFP CGB3 KRT7
6 cystadenofibroma 29.9 AFP KRT7 SERPINA1
7 seminoma 29.9 AFP ALPP CGB3
8 gastric adenocarcinoma 29.0 AFP CHGA KRT7
9 childhood endodermal sinus tumor 12.5
10 adult endodermal sinus tumor 12.4
11 mediastinal endodermal sinus tumors 12.3
12 central nervous system endodermal sinus tumor 12.2
13 childhood ovarian endodermal sinus tumor 12.2
14 yolk sac tumor of central nervous system 11.4
15 testicular germ cell tumor 11.3
16 corpus luteum cyst 10.8 AFP MUC16
17 polyembryoma 10.8 AFP SERPINA1
18 opisthorchiasis 10.8 AFP MUC16
19 ovarian cyst 10.8 AFP MUC16
20 hepatoid adenocarcinoma 10.7 AFP ALB
21 sternum cancer 10.7 AFP VIM
22 esophageal varix 10.7 AFP ALB
23 constrictive pericarditis 10.7 ALB SERPINA1
24 adenofibroma 10.7 MUC16 VIM
25 rh isoimmunization 10.6 AFP ALB
26 rete testis adenocarcinoma 10.6 AFP KLK3
27 ulcerative stomatitis 10.6 ALB CGB3
28 transient arthritis 10.6 ALB SERPINA1
29 tuberculous peritonitis 10.6 ALB MUC16
30 adult teratoma 10.6 AFP CHGA
31 polyposis, skin pigmentation, alopecia, and fingernail changes 10.6 ALB SERPINA1
32 bladder neck obstruction 10.6 AFP KLK3
33 sclerosing hepatic carcinoma 10.6 AFP CHGA
34 epididymitis 10.6 CGB3 KLK3
35 rete testis neoplasm 10.6 AFP KLK3
36 pancreatic acinar cell adenocarcinoma 10.6 AFP CHGA
37 protein-losing enteropathy 10.6 ALB SERPINA1
38 peliosis hepatis 10.6 AFP VIM
39 malignant teratoma 10.6 AFP SALL4
40 liver sarcoma 10.6 AFP CHGA
41 hepatic vascular disease 10.5 AFP ALB
42 placental site trophoblastic tumor 10.5 CGB3 SALL4
43 acinar cell cystadenocarcinoma 10.5 CHGA SERPINA1
44 intrahepatic bile duct adenoma 10.5 AFP KRT7
45 extragonadal seminoma 10.5 AFP SALL4
46 renal pelvis adenocarcinoma 10.5 AFP KRT7
47 vein disease 10.5 AFP ALB
48 bile duct cystadenocarcinoma 10.5 AFP KRT7
49 intratubular embryonal carcinoma 10.4 AFP KRT7
50 chordoid meningioma 10.4 CHGA VIM

Graphical network of the top 20 diseases related to Endodermal Sinus Tumor:



Diseases related to Endodermal Sinus Tumor

Symptoms & Phenotypes for Endodermal Sinus Tumor

GenomeRNAi Phenotypes related to Endodermal Sinus Tumor according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Reduced mammosphere formation GR00396-S 9.02 AFP ALB CHGA KRT7 VIM

Drugs & Therapeutics for Endodermal Sinus Tumor

Drugs for Endodermal Sinus Tumor (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 143)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Bleomycin Approved, Investigational Phase 2, Phase 3,Phase 3 11056-06-7 5360373
2
Cisplatin Approved Phase 2, Phase 3,Phase 3,Phase 1 15663-27-1 84093 441203 2767
3
Etoposide Approved Phase 2, Phase 3,Phase 3,Phase 1 33419-42-0 36462
4
Lenograstim Approved, Investigational Phase 2, Phase 3,Phase 3,Phase 1 135968-09-1
5
Paclitaxel Approved, Vet_approved Phase 2, Phase 3,Phase 3,Phase 1 33069-62-4 36314
6
Ifosfamide Approved Phase 3,Phase 1,Phase 2 3778-73-2 3690
7
Mechlorethamine Approved, Investigational Phase 3,Phase 1,Phase 2 51-75-2 4033
8
Oxaliplatin Approved, Investigational Phase 3,Phase 1 61825-94-3 5310940 9887054 43805 6857599
9
Dexamethasone Approved, Investigational, Vet_approved Phase 3,Phase 1,Phase 2 50-02-2 5743
10
Mesna Approved, Investigational Phase 3,Phase 1,Phase 2 3375-50-6 598
11
Captopril Approved Phase 3 62571-86-2 44093
12
Cyclophosphamide Approved, Investigational Phase 3,Phase 1 50-18-0, 6055-19-2 2907
13
Palivizumab Approved, Investigational Phase 3 188039-54-5
14
Ribavirin Approved Phase 3 36791-04-5 37542
15
Fluconazole Approved, Investigational Phase 3 86386-73-4 3365
16
Itraconazole Approved, Investigational Phase 3 84625-61-6 55283
17
Miconazole Approved, Investigational, Vet_approved Phase 3 22916-47-8 4189
18
Amphotericin B Approved, Investigational Phase 3 1397-89-3 14956 5280965
19
Caspofungin Approved Phase 3 179463-17-3, 162808-62-0 468682 2826718
20
Carboplatin Approved Phase 3,Phase 2,Phase 1 41575-94-4 10339178 498142 38904
21
Granisetron Approved, Investigational Phase 3 109889-09-0 3510
22
Ondansetron Approved Phase 3 99614-02-5 4595
23
Diphenhydramine Approved, Investigational Phase 3 147-24-0, 58-73-1 3100
24
Promethazine Approved, Investigational Phase 3 60-87-7 4927
25
Vinblastine Approved Phase 3 865-21-4 13342 241903
26 Albumin-Bound Paclitaxel Phase 2, Phase 3,Phase 3,Phase 1
27 Anti-Bacterial Agents Phase 2, Phase 3,Phase 3,Phase 1
28 Antibiotics, Antitubercular Phase 2, Phase 3,Phase 3
29 Antimitotic Agents Phase 2, Phase 3,Phase 3,Phase 1
30 Antineoplastic Agents, Phytogenic Phase 2, Phase 3,Phase 3,Phase 1
31 Etoposide phosphate Phase 2, Phase 3,Phase 3,Phase 1
32 Topoisomerase Inhibitors Phase 2, Phase 3,Phase 3,Phase 1
33 Alkylating Agents Phase 3,Phase 1,Phase 2
34 Antineoplastic Agents, Alkylating Phase 3,Phase 1,Phase 2
35
Isophosphamide mustard Phase 3,Phase 1,Phase 2 0
36 Immunosuppressive Agents Phase 3,Phase 1,Phase 2
37 Anti-Infective Agents Phase 3,Phase 1,Phase 2
38 Antimetabolites Phase 3,Phase 1,Phase 2
39 Antiviral Agents Phase 3,Phase 1,Phase 2
40 BB 1101 Phase 3,Phase 1,Phase 2
41 Dexamethasone acetate Phase 3,Phase 1,Phase 2 1177-87-3
42 Adjuvants, Immunologic Phase 3,Phase 1,Phase 2
43 Angiotensin-Converting Enzyme Inhibitors Phase 3
44 Antihypertensive Agents Phase 3
45 Antirheumatic Agents Phase 3,Phase 1
46 HIV Protease Inhibitors Phase 3,Phase 1
47
protease inhibitors Phase 3,Phase 1
48 Antibodies Phase 3,Phase 1
49 Antibodies, Monoclonal Phase 3,Phase 1
50 Immunoglobulins Phase 3,Phase 1

Interventional clinical trials:

(show top 50) (show all 59)
# Name Status NCT ID Phase Drugs
1 Combination Chemotherapy in Treating Men With Germ Cell Cancer Unknown status NCT00003643 Phase 2, Phase 3 cisplatin;etoposide;paclitaxel
2 Combination Chemotherapy in Treating Patients With Stage II or Stage III Germ Cell Tumors Unknown status NCT00104676 Phase 3 cisplatin;etoposide;ifosfamide;oxaliplatin;paclitaxel
3 Surgery and Combination Chemotherapy in Treating Children With Extracranial Germ Cell Tumors Completed NCT00053352 Phase 3 cisplatin;etoposide
4 Captopril in Treating Patients Undergoing Bone Marrow or Stem Cell Transplantation Completed NCT00004230 Phase 3 captopril;cyclophosphamide
5 Ribavirin With or Without Monoclonal Antibody Therapy in Treating Patients Who Develop RSV Pneumonia Following Peripheral Stem Cell Transplantation Completed NCT00014391 Phase 3 ribavirin
6 Itraconazole Compared With Fluconazole to Prevent Infections in Patients Undergoing Peripheral Stem Cell or Bone Marrow Transplantation Completed NCT00003883 Phase 3 fluconazole;itraconazole
7 Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment Completed NCT00008359 Phase 3 caspofungin acetate;liposomal amphotericin B
8 Liposomal Amphotericin B in Treating Granulocytopenia and Persistent Unexplained Fever in Cancer Patients Completed NCT00003938 Phase 3 liposomal amphotericin B
9 Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Men With Previously Untreated Germ Cell Cancer Completed NCT00003941 Phase 3 cisplatin;etoposide;ifosfamide
10 Combination Chemotherapy With or Without Bone Marrow or Stem Cell Transplantation in Treating Men With Untreated Germ Cell Tumors Completed NCT00002596 Phase 3 carboplatin;cisplatin;cyclophosphamide;etoposide
11 Combination Chemotherapy and Radiation Therapy in Treating Patients With Germ Cell Tumors in the Brain Completed NCT00293358 Phase 3 carboplatin;cisplatin;etoposide phosphate;ifosfamide
12 Acupressure in Controlling Nausea in Young Patients Receiving Highly Emetogenic Chemotherapy Completed NCT01346267 Phase 3
13 Active Surveillance, Bleomycin, Carboplatin, Etoposide, or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors Recruiting NCT03067181 Phase 3 Bleomycin;Carboplatin;Cisplatin;Etoposide
14 Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors Recruiting NCT02375204 Phase 3 paclitaxel;ifosfamide;cisplatin;pegylated G-CSF;G-CSF;carboplatin;etoposide phosphate
15 Cisplatin and Ifosfamide Combined With Either Paclitaxel or Vinblastine in Treating Men With Progressive or Recurrent Metastatic Germ Cell Tumors Terminated NCT00072215 Phase 3 cisplatin;ifosfamide;paclitaxel;vinblastine
16 Gemcitabine, Paclitaxel, Ifosfamide, and Cisplatin in Treating Patients With Progressive or Relapsed Metastatic Germ Cell Tumors Unknown status NCT00551122 Phase 1, Phase 2 cisplatin;gemcitabine hydrochloride;ifosfamide;paclitaxel
17 Combination Chemotherapy in Treating Young Patients With Recurrent or Resistant Malignant Germ Cell Tumors Completed NCT00467051 Phase 2 paclitaxel;carboplatin;ifosfamide
18 Combination Chemotherapy and Pegfilgrastim in Treating Patients With Previously Untreated Germ Cell Tumors Completed NCT00470366 Phase 2 cisplatin;ifosfamide;paclitaxel
19 Sunitinib in Treating Patients With Metastatic Germ Cell Tumors That Have Relapsed or Not Responded to Treatment Completed NCT00453310 Phase 2 sunitinib malate
20 Immunotherapy in Treating Patients Who Are Undergoing Bone Marrow or Peripheral Stem Cell Transplantation Completed NCT00002673 Phase 2
21 Lymphocyte Infusion in Treating Patients With Relapsed Cancer After Bone Marrow or Peripheral Stem Cell Transplantation Completed NCT00003887 Phase 2
22 Beclomethasone in Treating Patients With Graft-Versus-Host Disease of the Esophagus, Stomach, Small Intestine, or Colon Completed NCT00010283 Phase 1, Phase 2 beclomethasone dipropionate
23 Interleukin-11 Plus Filgrastim Prior to Peripheral Stem Cell Transplantation in Patients With Non-Hodgkin's Lymphoma, Hodgkin's Disease, Breast Cancer, or Other Solid Tumors Completed NCT00004157 Phase 2
24 Biological Therapy Following Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Cancer Completed NCT00003408 Phase 2
25 Combination Chemotherapy and Pegfilgrastim in Treating Men With Metastatic Germ Cell Tumors Completed NCT00453232 Phase 2 cisplatin;etoposide
26 Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Relapsed Germ Cell Cancer Completed NCT00002931 Phase 2 carboplatin;etoposide;ifosfamide;paclitaxel
27 Ixabepilone in Treating Patients With Advanced Cisplatin-Refractory Germ Cell Tumors Completed NCT00070096 Phase 2 ixabepilone
28 Combination Chemotherapy in Treating Male Patients With Germ Cell Tumors Completed NCT00301782 Phase 2 carboplatin;cisplatin;etoposide phosphate;vincristine sulfate
29 Paclitaxel, Ifosfamide, and Cisplatin in Treating Patients With Metastatic Testicular Cancer Completed NCT00004077 Phase 2 cisplatin;ifosfamide;paclitaxel
30 Neoadjuvant Chemotherapy With or Without Second-Look Surgery Followed by Radiation Therapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Intracranial Germ Cell Tumors Completed NCT00047320 Phase 2 carboplatin;etoposide;ifosfamide;thiotepa
31 Temozolomide Followed by Radiation Therapy in Treating Children With Newly Diagnosed Malignant CNS Tumors Completed NCT00005955 Phase 2 temozolomide
32 Cisplatin and Etoposide Prior to Radiation Therapy in Treating Patients With CNS Tumors Completed NCT00002472 Phase 2 cisplatin;etoposide
33 Role of Axumin PET Scan in Germ Cell Tumor Recruiting NCT03426865 Phase 2 Axumin PET scan
34 Autologous Peripheral Blood Stem Cell Transplant for Germ Cell Tumors Recruiting NCT00432094 Phase 2 carboplatin;etoposide;ifosfamide;paclitaxel;thiotepa;Mesna
35 Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors Active, not recruiting NCT00788125 Phase 1, Phase 2 carboplatin;dasatinib;etoposide phosphate;ifosfamide
36 MEN-10755 in Treating Patients With Solid Tumors Completed NCT00003982 Phase 1 sabarubicin
37 Ipilimumab After Allogeneic Stem Cell Transplant in Treating Patients With Persistent or Progressive Cancer Completed NCT00060372 Phase 1 ipilimumab;therapeutic allogeneic lymphocytes
38 Sunitinib in Treating Young Patients With Refractory Solid Tumors Completed NCT00387920 Phase 1 sunitinib malate
39 Combination Chemotherapy in Treating Young Patients With Advanced Solid Tumors Completed NCT00281944 Phase 1 oxaliplatin;fluorouracil;leucovorin calcium
40 Vorinostat and Temozolomide in Treating Young Patients With Relapsed or Refractory Primary Brain Tumors or Spinal Cord Tumors Completed NCT01076530 Phase 1 vorinostat;temozolomide
41 Pazopanib Hydrochloride in Treating Young Patients With Solid Tumors That Have Relapsed or Not Responded to Treatment Completed NCT00929903 Phase 1 pazopanib hydrochloride
42 Vorinostat and Bortezomib in Treating Young Patients With Refractory or Recurrent Solid Tumors, Including Central Nervous System Tumors and Lymphoma Completed NCT00994500 Phase 1 vorinostat;bortezomib
43 Interleukin-12 in Treating Patients With Hematologic Cancers or Solid Tumors Completed NCT00003107 Phase 1
44 Lapatinib and Paclitaxel in Treating Patients With Advanced Solid Tumors Completed NCT00313599 Phase 1 lapatinib;paclitaxel
45 Biological Therapy in Treating Patients With Metastatic Cancer Completed NCT00004604 Phase 1
46 Imetelstat Sodium in Treating Young Patients With Refractory or Recurrent Solid Tumors or Lymphoma Completed NCT01273090 Phase 1 imetelstat sodium
47 PTC299 in Treating Young Patients With Refractory or Recurrent Primary Central Nervous System Tumors Completed NCT01158300 Phase 1 VEGF inhibitor PTC299
48 Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Infants With Malignant Brain or Spinal Cord Tumors Completed NCT00003141 Phase 1 carboplatin;cisplatin;cyclophosphamide;etoposide;thiotepa;vincristine sulfate
49 Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia Terminated NCT01088763 Phase 1 gamma-secretase/Notch signalling pathway inhibitor RO4929097;dexamethasone
50 Acetylcysteine, Mannitol, Combination Chemotherapy, and Sodium Thiosulfate in Treating Children With Malignant Brain Tumors Terminated NCT00238173 Phase 1 acetylcysteine;carboplatin;cyclophosphamide;etoposide phosphate;mannitol;sodium thiosulfate

Search NIH Clinical Center for Endodermal Sinus Tumor

Cochrane evidence based reviews: endodermal sinus tumor

Genetic Tests for Endodermal Sinus Tumor

Anatomical Context for Endodermal Sinus Tumor

MalaCards organs/tissues related to Endodermal Sinus Tumor:

41
Ovary, Bone, Brain, Bone Marrow, Spinal Cord, Liver, Pineal

Publications for Endodermal Sinus Tumor

Articles related to Endodermal Sinus Tumor:

(show top 50) (show all 375)
# Title Authors Year
1
Ovarian Yolk Sac Tumors; Does Age Matter? ( 29194189 )
2018
2
Testicular Yolk Sac Tumor and Mature Teratoma: Synchronous Bilateral Occurrence in an Infant. ( 29608939 )
2018
3
A Rare Case of Pediatric Vaginal Yolk Sac Tumor. ( 29548872 )
2018
4
Management and prognosis of ovarian yolk sac tumors; an analysis of the National Cancer Data Base. ( 28803748 )
2017
5
Vaginal Yolk Sac Tumor in an Infant. ( 28969744 )
2017
6
Conservative management of primary vaginal endodermal sinus tumor and rhabdomyosarcoma. ( 28969004 )
2017
7
Yolk sac tumor of upper lip: A case report. ( 29113273 )
2017
8
ZBTB16: a novel sensitive and specific biomarker for yolk sac tumor. ( 26916077 )
2016
9
Successful treatment of mixed yolk sac tumor and mature teratoma in the spinal cord: case report. ( 27911225 )
2016
10
Germ Cell Tumor Targeting Chemotherapy in Gastric Adenocarcinoma with an Endodermal Sinus Tumor Component: A Case Report. ( 27351795 )
2016
11
Brief Report: A Second Primary Endodermal Sinus Tumor 9A Years after Initial Diagnosis. ( 27818263 )
2016
12
Retroperitoneal Endodermal Sinus Tumor Patient with Palliative Care Needs. ( 26962288 )
2016
13
Sinonasal yolk sac (Endodermal sinus) tumor in an adult female--A case report and review of the literature. ( 26095665 )
2015
14
Testicular yolk sac tumor and impaired spermatogenesis in a Holstein Friesian calf. ( 26214222 )
2015
15
Vaginal Yolk Sac Tumor in an Infant: A Case Report and Literature Review of the Last 30 Years. ( 25851552 )
2015
16
Pediatric Vaginal Yolk Sac Tumor: Reappraisal of Treatment Strategy in a Rare Tumor at a Unique Location. ( 25929614 )
2015
17
Primary juxtaovarian yolk sac tumor concurrent with an ipsilateral ovarian mature teratoma in an adult woman: a rare association. ( 25755817 )
2015
18
Endoscopic surgery combining chemotherapy for vaginal yolk-sac tumor: a case report. ( 26189265 )
2015
19
Advanced childhood testicular yolk sac tumor with bone metastasis: a case report. ( 25733287 )
2015
20
Prognosis of eight Chinese cases of primary vaginal yolk sac tumor with a review of the literature. ( 25422231 )
2014
21
Mixed ovarian germ cell tumor composed of immature teratoma, yolk sac tumor and embryonal carcinoma. ( 25518772 )
2014
22
Gonadoblastoma and hepatoid and endometrioid-like yolk sac tumor: an update. ( 24901396 )
2014
23
Primary cerebellar endodermal sinus tumor: A case report. ( 25202397 )
2014
24
Ruptured testicular yolk sac tumor. ( 25148504 )
2014
25
Experience with the treatment of testicular yolk sac tumor in children: a report of 14 cases. ( 25555873 )
2014
26
SALL4 and SF-1 are sensitive and specific markers for distinguishing granulosa cell tumors from yolk sac tumors. ( 22832114 )
2013
27
Endodermal sinus tumor of vagina posing a diagnostic challenge and managed by chemotherapy and novel posterior sagittal surgical approach: Lessons learned. ( 24118204 )
2013
28
Treatment of ovarian endodermal sinus tumor to preserve fertility. ( 23351423 )
2013
29
Sacrococcygeal yolk sac tumor developing after teratoma: a clinicopathological study of pediatric sacrococcygeal germ cell tumors and a proposal of the pathogenesis of sacrococcygeal yolk sac tumors. ( 23583133 )
2013
30
Immunohistochemical expression of SALL4 in hepatocellular carcinoma, a potential pitfall in the differential diagnosis of yolk sac tumors. ( 23347651 )
2013
31
Primary endodermal sinus tumor in the posterior cranial fossa: clinical analysis of 7 cases. ( 24382224 )
2013
32
Gastric adenocarcinoma with yolk sac tumor differentiation and liver metastasis of yolk sac tumor component. ( 24294529 )
2013
33
Endometrial carcinoma with yolk sac tumor-like differentiation and elevated serum I^-hCG: a case report and literature review. ( 24187502 )
2013
34
Testicular yolk sac tumor of myxomatous, reticular, and polyvesicular vitelline type in a newborn calf. ( 24153035 )
2013
35
Yolk sac tumor of the bilateral basal ganglia in a patient with Down syndrome. ( 23306965 )
2013
36
Testicular yolk sac tumor. ( 23945483 )
2013
37
Occurrence of metachronous pure germinomas long after treatment of a mixed germ cell tumor containing yolk sac tumor and germinoma. ( 23082803 )
2013
38
Endodermal sinus tumor of vagina in infants. ( 23888222 )
2013
39
Endodermal sinus tumor of the ovary in an 86A year old woman. ( 24371620 )
2012
40
The clinical features and treatment of endodermal sinus tumor of vagina. ( 22819272 )
2012
41
Oral extragonadal yolk sac tumor in a patient with Aicardi syndrome: putative origin and differential diagnosis. ( 22225777 )
2012
42
Endodermal Sinus Tumor Presented With Ascites: A Case Report. ( 27785191 )
2012
43
Metrorrhagia in a child with an endodermal sinus tumor of the vagina A case report. ( 23103591 )
2012
44
Precocious puberty secondary to a mixed germ cell-sex cord-stromal tumor associated with an ovarian yolk sac tumor: a case report. ( 22734844 )
2012
45
Endodermal sinus tumor of testis with acute intestinal obstruction: A rare presentation. ( 22279365 )
2012
46
Evaluation of cloned cells, animal model, and ATRA sensitivity of human testicular yolk sac tumor. ( 22410253 )
2012
47
Endodermal sinus tumor of the vagina in a child. ( 24293886 )
2012
48
Conservative treatment and long-term follow up of endodermal sinus tumor of the vagina. ( 22178761 )
2012
49
Mixed germ cell tumor with extensive yolk sac tumor elements in the frontal lobe of an adult. ( 23326746 )
2012
50
Type 2 sacrococcygeal teratoma endodermal sinus tumor. ( 22124518 )
2011

Variations for Endodermal Sinus Tumor

Expression for Endodermal Sinus Tumor

Search GEO for disease gene expression data for Endodermal Sinus Tumor.

Pathways for Endodermal Sinus Tumor

Pathways related to Endodermal Sinus Tumor according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.15 AFP ALB ALPP SERPINA1 VIM
2
Show member pathways
10.82 KLK3 SERPINA1
3 10.6 AFP ALB

GO Terms for Endodermal Sinus Tumor

Cellular components related to Endodermal Sinus Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.5 AFP ALB CGB3 CHGA KLK3 MUC16
2 extracellular space GO:0005615 9.17 AFP ALB CGB3 CHGA KLK3 MUC16

Biological processes related to Endodermal Sinus Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 8.92 AFP ALB KLK3 SERPINA1

Sources for Endodermal Sinus Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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