MCID: END080
MIFTS: 45

Endometrial Disease

Categories: Reproductive diseases

Aliases & Classifications for Endometrial Disease

MalaCards integrated aliases for Endometrial Disease:

Name: Endometrial Disease 12 15
Endometrial Disorder 54 71
Endometrial Diseases 71

Classifications:



External Ids:

Disease Ontology 12 DOID:1005
NCIt 49 C3504
UMLS 71 C0151622 C1720816

Summaries for Endometrial Disease

Disease Ontology : 12 A uterine disease that is located in the endometrium.

MalaCards based summary : Endometrial Disease, also known as endometrial disorder, is related to endometritis and endometriosis. An important gene associated with Endometrial Disease is ESR1 (Estrogen Receptor 1), and among its related pathways/superpathways are Innate Immune System and Akt Signaling. The drugs Mepivacaine and Bupivacaine have been mentioned in the context of this disorder. Affiliated tissues include endometrium, breast and bone, and related phenotypes are cardiovascular system and hematopoietic system

Related Diseases for Endometrial Disease

Diseases related to Endometrial Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 434, show less)
# Related Disease Score Top Affiliating Genes
1 endometritis 31.2 TNF TLR4 TLR2 SIGLEC5 SDC1 OXT
2 endometriosis 30.2 PTGS2 IL6 IL1B ESR1 CYP19A1 CXCL8
3 adenomyosis 29.9 PTGS2 OXT ESR1 CYP19A1 CXCL8
4 pre-eclampsia 29.6 TNF TLR4 OXT IL6 IL1B CXCL8
5 tamoxifen-related endometrial lesion 11.1
6 granulomatous endometritis 10.6 SDC1 ESR1
7 breast juvenile papillomatosis 10.6 OXT ESR1
8 external pathological resorption 10.6 TNF IL6
9 postmenopausal atrophic vaginitis 10.6 OXT ESR1 CYP19A1
10 mycobacterium chelonae 10.6 TLR2 CXCL8
11 scorpion envenomation 10.6 TNF IL6
12 angelucci's syndrome 10.6 IL1B CXCL8
13 dermatitis, atopic, 8 10.6 IL1B CXCL8
14 systemic onset juvenile idiopathic arthritis 10.6 TNF IL1B
15 mycobacterium marinum 10.5 TLR2 CXCL8
16 staphylococcal toxic shock syndrome 10.5 TNF IL1B
17 acute transverse myelitis 10.5 IL6 CXCL8
18 osteosclerotic myeloma 10.5 IL6 IL1B
19 periodontitis, chronic 10.5 IL6 IL1B
20 vulvar vestibulitis syndrome 10.5 TNF IL1B ESR1
21 mycobacterium kansasii 10.5 TLR2 CXCL8
22 esophagus melanoma 10.5 IL1B CXCL8
23 angioimmunoblastic lymphadenopathy with dysproteinemia 10.5 TNF IL6
24 myelitis 10.5 TNF IL6 CXCL8
25 recurrent corneal erosion 10.5 IL6 IL1B CXCL8
26 pustulosis of palm and sole 10.5 TNF SIGLEC5 CXCL8
27 leukoregulin 10.5 PTGS2 CXCL8
28 idiopathic anterior uveitis 10.5 TNF IL6 CXCL8
29 estrogen-receptor negative breast cancer 10.5 ESR1 CYP19A1 CXCL8
30 streptococcal toxic-shock syndrome 10.5 TNF IL6 CXCL8
31 uremic pruritus 10.5 IL6 IL1B
32 palladium allergic contact dermatitis 10.5 TNF IL1B
33 pouchitis 10.5 TLR4 CXCL8
34 funisitis 10.5 IL6 IL1B CXCL8
35 kashin-beck disease 10.5 TNF IL1B
36 conjunctivochalasis 10.5 IL6 IL1B CXCL8
37 post-cardiac arrest syndrome 10.5 SDC1 IL6 CXCL8
38 ascaris lumbricoides infection 10.5 IL6 IL1B CXCL8
39 stachybotrys chartarum 10.5 TNF IL6 IL1B
40 eales disease 10.5 TNF IL6 IL1B
41 meningococcal meningitis 10.5 TLR4 TLR2 SIGLEC5
42 cardiac sarcoidosis 10.5 TNF IL1B CXCL8
43 cervical incompetence 10.5 OXT MFN2 IL6
44 cysticercosis 10.5 TLR4 IL6 IL1B
45 transverse myelitis 10.5 TNF IL6 CXCL8
46 encephalomalacia 10.5 TLR4 IL6 IL1B
47 opisthorchiasis 10.5 TNF IL1B CXCL8
48 acute generalized exanthematous pustulosis 10.5 PTGS2 CXCL8
49 laryngitis 10.5 TNF IL6 IL1B
50 congenital cytomegalovirus 10.5 TNF TLR2 IL1B
51 suppurative otitis media 10.5 TLR4 TLR2 IL1B
52 glossitis 10.5 TNF IL6 IL1B
53 haemophilus influenzae 10.5 TNF TLR2 CXCL8
54 polyradiculopathy 10.5 TNF IL6 IL1B
55 trichomoniasis 10.4 TNF IL6 CXCL8
56 pyoderma 10.4 TNF SIGLEC5 CXCL8
57 chronic conjunctivitis 10.4 TNF IL6 CXCL8
58 pyoderma gangrenosum 10.4 TNF SIGLEC5 CXCL8
59 subacute thyroiditis 10.4 TNF IL6 IL1B
60 crohn's colitis 10.4 TNF IL1B CXCL8
61 burning mouth syndrome 10.4 TNF IL6 IL1B
62 poems syndrome 10.4 TNF IL6 IL1B
63 chronic recurrent multifocal osteomyelitis 10.4 TNF IL6 IL1B
64 trachoma 10.4 TNF IL6 HP
65 macular retinal edema 10.4 TNF IL6 CXCL8
66 autoimmune gastritis 10.4 TNF IL6 IL1B
67 cyclic neutropenia 10.4 TNF IL1B CXCL8
68 toxic pneumonitis 10.4 TLR6 TLR4
69 vitreous disease 10.4 TNF IL6 CXCL8
70 cecal disease 10.4 TNF IL6 CXCL8
71 bone deterioration disease 10.4 TNF IL6 IL1B
72 tuberculous meningitis 10.4 TNF TLR2 CXCL8
73 blepharitis 10.4 TNF IL6 CXCL8
74 newborn respiratory distress syndrome 10.4 IL6 IL1B CXCL8
75 lichen disease 10.4 TNF IL6 CXCL8
76 juvenile nasopharyngeal angiofibroma 10.4 TLR3 ESR1 CYP19A1
77 aseptic meningitis 10.4 TNF IL1B CXCL8
78 spinal cord injury 10.4 TNF IL6 CXCL8
79 carpal tunnel syndrome 10.4 IL6 IL1B ESR1
80 cystic echinococcosis 10.4 TLR4 TLR2 IL6
81 periodic fever, familial, autosomal dominant 10.4 TNF IL6 IL1B
82 apnea, obstructive sleep 10.4 TNF IL6 CXCL8
83 fuchs' heterochromic uveitis 10.4 IL6 CXCL8
84 alveolar echinococcosis 10.4 TNF TLR4 TLR2
85 protein-energy malnutrition 10.4 TNF IL6 HP
86 cinca syndrome 10.4 TLR4 IL6 IL1B
87 dengue shock syndrome 10.4 TNF IL6 IL1B
88 hemometra 10.4 OXT MFN2
89 fungal keratitis 10.4 TLR4 TLR2
90 diverticulitis 10.4 TNF SDC1 IL6
91 uterine benign neoplasm 10.4 OXT MFN2 ESR1 CYP19A1
92 endogenous depression 10.4 OXT IL6 IL1B
93 reproductive organ benign neoplasm 10.4 OXT MFN2 ESR1 CYP19A1
94 cerebral artery occlusion 10.4 TNF PTGS2 IL1B
95 lymphocytic choriomeningitis 10.4 TLR2 IL6 CXCL8
96 toxicodendron dermatitis 10.4 TNF CXCL8
97 dry eye syndrome 10.4 TNF IL6 ESR1
98 extrapulmonary tuberculosis 10.4 TNF TLR2 IL1B
99 retinal vein occlusion 10.4 TNF IL6 CXCL8
100 monoclonal gammopathy of uncertain significance 10.4 TNF SDC1 IL6
101 mycoplasma pneumoniae pneumonia 10.4 TNF TLR2 IL6
102 exanthem 10.4 TNF IL6 CXCL8
103 graft-versus-host disease 10.4 TNF IL6 IL1B
104 pre-malignant neoplasm 10.4 PTGS2 ESR1 CYP19A1
105 pulmonary alveolar proteinosis 10.4 TNF IL6 CXCL8
106 keratoconjunctivitis 10.4 TNF IL6 CXCL8
107 lymphoid interstitial pneumonia 10.4 TNF SDC1 IL6
108 pain agnosia 10.4 PTGS2 OXT IL6
109 acute pericementitis 10.4 TLR6 TLR2
110 agnosia 10.4 PTGS2 OXT IL6
111 breast carcinoma in situ 10.4 SDC1 IL6 ESR1 CYP19A1
112 myoma 10.4 OXT MFN2 ESR1 CYP19A1
113 hypotrichosis 1 10.4 TNF IL6 CXCL8
114 bone resorption disease 10.4 TNF IL6 ESR1 CYP19A1
115 bone remodeling disease 10.4 TNF IL6 ESR1 CYP19A1
116 optic neuritis 10.4 TNF IL1B CXCL8
117 extrinsic allergic alveolitis 10.4 IL6 IL1B HP CXCL8
118 limb ischemia 10.4 TNF SIGLEC5 IL6
119 endometrial stromal sarcoma 10.4 IL6 ESR1 CYP19A1 CXCL8
120 meconium aspiration syndrome 10.4 TNF OXT IL6 CXCL8
121 chikungunya 10.4 TNF IL6 IL1B
122 irritant dermatitis 10.4 TNF IL6 IL1B CXCL8
123 indolent myeloma 10.4 IL6 IL1B
124 fasciitis 10.4 TNF IL6 ESR1 CXCL8
125 neonatal jaundice 10.4 TNF OXT IL6 IL1B
126 prosthetic joint infection 10.4 TLR4 TLR2 IL6 IL1B
127 bagassosis 10.4 TNF IL6 IL1B CXCL8
128 severe acute respiratory syndrome 10.3 TNF IL6 CXCL8
129 drug-induced lupus erythematosus 10.3 TNF IL6 IL1B CXCL8
130 idiopathic neutropenia 10.3 TNF TLR4 IL6 IL1B
131 blood coagulation disease 10.3 TNF SIGLEC5 IL6 HP
132 pulpitis 10.3 TNF IL6 IL1B CXCL8
133 lacrimal apparatus disease 10.3 TNF IL6 IL1B CXCL8
134 adult-onset still's disease 10.3 TNF IL6 IL1B CXCL8
135 silicosis 10.3 TNF TLR4 IL1B CXCL8
136 null-cell leukemia 10.3 TNF IL6
137 cytomegalovirus infection 10.3 TNF IL6 IL1B CXCL8
138 complex regional pain syndrome 10.3 TNF IL6 IL1B CXCL8
139 ileus 10.3 TNF IL6 IL1B
140 uveal disease 10.3 TNF IL6 CXCL8
141 pericarditis 10.3 TNF IL6 IL1B CXCL8
142 autoimmune disease of gastrointestinal tract 10.3 TNF TLR4 IL6 HP
143 shigellosis 10.3 TNF TLR4 IL1B CXCL8
144 lymphadenitis 10.3 TNF TLR4 IL1B CXCL8
145 cervicitis 10.3 TLR4 TLR2 IL6 CXCL8
146 prostatitis 10.3 TNF IL6 IL1B CXCL8
147 peptic esophagitis 10.3 PTGS2 IL6 IL1B CXCL8
148 pleural disease 10.3 TNF IL6 IL1B CXCL8
149 allergic contact dermatitis 10.3 TNF IL6 IL1B CXCL8
150 hellp syndrome 10.3 TLR4 IL6 HP CXCL8
151 neuritis 10.3 TNF IL6 IL1B CXCL8
152 typhoid fever 10.3 TNF TLR4 IL6 IL1B
153 obstructive jaundice 10.3 TNF TLR4 IL6 CXCL8
154 retinal vascular disease 10.3 TNF IL6 IL1B CXCL8
155 brucellosis 10.3 TNF TLR4 IL6 CXCL8
156 bronchiolitis obliterans 10.3 TNF TLR4 IL6 CXCL8
157 hand, foot and mouth disease 10.3 TLR4 TLR3 IL6
158 arthropathy 10.3 TNF PTGS2 IL6 IL1B
159 adult respiratory distress syndrome 10.3 TNF IL6 IL1B CXCL8
160 fibromyalgia 10.3 TNF IL6 IL1B CXCL8
161 intracranial berry aneurysm 10.3 TNF TLR4 IL6 HP
162 scrub typhus 10.3 TNF TLR4 TLR2 IL1B
163 sleep apnea 10.3 TNF IL6 IL1B CXCL8
164 amebiasis 10.3 TNF TLR4 TLR2 CXCL8
165 gastroenteritis 10.3 TNF IL6 IL1B CXCL8
166 blau syndrome 10.3 TNF TLR4 TLR2 IL1B
167 mammographic density 10.3 ESR1 CYP19A1
168 pneumonic tularemia 10.3 TNF TLR4 TLR2 IL6
169 tularemia 10.3 TNF TLR4 TLR2 IL6
170 juvenile rheumatoid arthritis 10.3 TNF IL6 IL1B CXCL8
171 avian influenza 10.3 TNF IL6 CXCL8
172 rheumatic fever 10.3 TNF TLR2 IL6 HP
173 endophthalmitis 10.3 TNF TLR2 IL6 CXCL8
174 synovitis 10.3 TNF IL6 IL1B CXCL8
175 pleurisy 10.3 TNF TLR4 TLR2 CXCL8
176 salpingitis 10.3 TNF TLR2 SIGLEC5 MFN2
177 chickenpox 10.3 TNF TLR3 IL6
178 primary systemic mycosis 10.3 TNF TLR4 TLR2 IL6
179 rosacea 10.3 TNF TLR2 IL6 CXCL8
180 rheumatic heart disease 10.3 TNF TLR2 IL6 IL1B
181 endometrial cancer 10.3
182 listeriosis 10.3 TNF TLR4 TLR2 IL6
183 echinococcosis 10.3 TNF TLR4 TLR2 IL6
184 paracoccidioidomycosis 10.3 TNF TLR4 TLR2 IL6
185 subacute sclerosing panencephalitis 10.3 TNF TLR3 IL6
186 autosomal genetic disease 10.3 TNF IL6 ESR1 CXCL8
187 inflammatory bowel disease 1 10.3 TNF TLR4 TLR2 IL6
188 lymph node disease 10.3 TNF TLR4 TLR2 IL6
189 ileitis 10.3 TNF TLR4 TLR2 IL6
190 exudative vitreoretinopathy 1 10.3 TNF IL6 CXCL8
191 interstitial lung disease 10.3 TNF IL6 IL1B CXCL8
192 allergic conjunctivitis 10.3 TNF TLR3 CXCL8
193 erythema multiforme 10.3 TNF PTGS2 IL6 CXCL8
194 food allergy 10.3 TNF TLR4 TLR2 CXCL8
195 myositis 10.3 TNF IL6 IL1B CXCL8
196 peptic ulcer disease 10.3 TNF PTGS2 IL1B CXCL8
197 non-alcoholic steatohepatitis 10.3 TNF IL6
198 lichen planus 10.3 TNF IL6 CXCL8
199 spondyloarthropathy 10.3 TNF IL6 IL1B
200 bronchiectasis 10.3 TNF TLR2 IL6 CXCL8
201 toxic encephalopathy 10.3 TNF PTGS2 IL6 IL1B
202 anaerobic pneumonia 10.3 TLR6 IL6
203 glucose metabolism disease 10.3 TNF TLR4 IL6 IL1B
204 mycobacterium abscessus 10.3 TNF TLR2 TLR1 CXCL8
205 suppression of tumorigenicity 12 10.3 PTGS2 IL6 ESR1 CXCL8
206 encephalitis 10.2 TNF TLR3 IL6 IL1B
207 acquired metabolic disease 10.2 TNF TLR4 IL6 IL1B
208 pulmonary edema 10.2 TNF OXT IL1B HP CXCL8
209 sudden infant death syndrome 10.2 TNF IL6 IL1B CXCL8
210 varicose veins 10.2 TNF IL6 CXCL8
211 neurosyphilis 10.2 TLR6 TLR2 TLR1 CXCL8
212 spondyloarthropathy 1 10.2 TNF TLR4 HP
213 leukemia, acute monocytic 10.2 TNF TLR4 SIGLEC5 IL6 CXCL8
214 polyneuropathy 10.2 TNF MFN2 IL6 IL1B
215 viral pneumonia 10.2 TNF TLR3 IL6 CXCL8
216 placenta disease 10.2 TNF OXT IL6 IL1B CXCL8
217 bronchopneumonia 10.2 TNF TLR4 IL6 HP CXCL8
218 mastitis 10.2 TLR2 OXT IL6 HP CXCL8
219 hepatitis a 10.2 TNF TLR4 TLR3 HP
220 septic arthritis 10.2 TLR4 TLR3 TLR2 CXCL8
221 myd88 deficiency 10.2 TLR6 TLR4 TLR2 TLR1
222 irak4 deficiency 10.2 TLR6 TLR4 TLR2 TLR1
223 appendicitis 10.2 TNF TLR4 IL6 IL1B CXCL8
224 pyelonephritis 10.2 TNF TLR4 IL6 IL1B CXCL8
225 lymphoma, mucosa-associated lymphoid type 10.2 TLR4 TLR2 TLR1 SDC1
226 sclerosing cholangitis 10.2 TNF TLR4 IL6 HP CXCL8
227 cholangitis 10.2 TNF TLR4 IL6 HP CXCL8
228 duodenal ulcer 10.2 TNF TLR4 IL6 IL1B CXCL8
229 dengue hemorrhagic fever 10.2 TNF TLR3 IL6 CXCL8
230 allergic hypersensitivity disease 10.2 TNF TLR4 TLR2 CXCL8
231 chronic fatigue syndrome 10.2 TNF TLR4 IL6 IL1B CXCL8
232 mumps 10.2 TNF TLR3 IL6 CXCL8
233 endocardium disease 10.2 TNF TLR2 SIGLEC5 IL6 CXCL8
234 cerebrovascular disease 10.2 TNF TLR4 IL6 HP
235 monocytic leukemia 10.2 TNF TLR4 IL6 IL1B CXCL8
236 ovarian disease 10.2 TNF IL6 ESR1 CYP19A1
237 relapsing-remitting multiple sclerosis 10.2 TNF TLR4 IL6 IL1B CXCL8
238 splenic disease 10.2 TNF TLR4 TLR2 SIGLEC5 IL6
239 acute pancreatitis 10.2 TNF TLR4 IL6 IL1B CXCL8
240 neurofibromatosis, type ii 10.2 TNF TLR2 SIGLEC5 IL6 CXCL8
241 pertussis 10.2 TNF TLR4 IL6 IL1B CXCL8
242 conjunctivitis 10.2 TNF TLR3 IL6 CXCL8
243 periapical periodontitis 10.2 TNF TLR2 IL6 IL1B CXCL8
244 parasitic helminthiasis infectious disease 10.2 TNF TLR4 TLR2 SIGLEC5 IL6
245 coronary artery anomaly 10.2 TNF IL6 IL1B HP CXCL8
246 rubella 10.2 TNF TLR4 TLR3 IL6
247 dermatitis 10.2 TNF TLR4 TLR2 IL6 CXCL8
248 fatty liver disease 10.2 TNF TLR4 IL6 IL1B CXCL8
249 visceral leishmaniasis 10.2 TNF TLR4 TLR2 IL1B CXCL8
250 atherosclerosis susceptibility 10.2 TNF TLR4 IL6 IL1B CXCL8
251 urethritis 10.2 TNF TLR4 TLR2 IL6 CXCL8
252 blood group, globoside system 10.2 TNF TLR4 TLR2 IL6 CXCL8
253 diarrhea 10.2 TNF TLR4 IL6 IL1B CXCL8
254 gingivitis 10.2 TNF TLR2 IL6 IL1B CXCL8
255 pyelitis 10.2 TNF TLR4 TLR2 IL6 CXCL8
256 ulcerative colitis 10.2 TNF TLR4 IL6 IL1B CXCL8
257 familial hypercholesterolemia 10.2 TNF IL6 ESR1 CXCL8
258 nasal cavity disease 10.2 TNF TLR4 TLR2 IL6 CXCL8
259 acute cystitis 10.2 TNF TLR4 TLR2 IL6 CXCL8
260 respiratory allergy 10.2 TNF TLR4 TLR2 IL6 CXCL8
261 hypersensitivity reaction type iv disease 10.2 TNF TLR4 TLR2 IL6 CXCL8
262 pulmonary tuberculosis 10.2 TNF TLR4 TLR2 IL6 HP
263 endometrial hyperplasia 10.2
264 familial mediterranean fever 10.2 TNF TLR4 TLR2 IL6 IL1B
265 pharyngitis 10.2 TNF PTGS2 IL6 IL1B CXCL8
266 cutaneous leishmaniasis 10.2 TNF TLR4 TLR2 IL6 CXCL8
267 gastric ulcer 10.2 TNF PTGS2 IL6 IL1B CXCL8
268 irritable bowel syndrome 10.2 TNF TLR4 TLR2 IL6 CXCL8
269 non-alcoholic fatty liver disease 10.2 TNF TLR4 IL6 IL1B CXCL8
270 esophagitis 10.2 TNF PTGS2 IL6 IL1B CXCL8
271 pneumoconiosis 10.2 TNF PTGS2 IL6 IL1B CXCL8
272 atrophic gastritis 10.2 TNF PTGS2 IL6 IL1B CXCL8
273 parenchymatous neurosyphilis 10.2 TLR6 TLR1
274 spondylarthropathy 10.2 TNF TLR4 TLR2 PTGS2 HP
275 cystitis 10.2 TNF TLR4 PTGS2 IL6 CXCL8
276 mycobacterium tuberculosis 1 10.2 TNF TLR4 TLR2 TLR1
277 psoriatic arthritis 10.1 TNF TLR4 TLR2 IL6 IL1B
278 respiratory failure 10.1 TNF SDC1 IL6 IL1B CXCL8
279 infective endocarditis 10.1 TNF TLR6 TLR2 SIGLEC5 IL6
280 vascular disease 10.1 TNF TLR4 PTGS2 IL6 HP
281 bacteriuria 10.1 TLR4 TLR2 TLR1 IL6 CXCL8
282 osteoarthritis 10.1 TNF PTGS2 IL6 IL1B CXCL8
283 endocarditis 10.1 TNF TLR6 TLR2 IL6 CXCL8
284 plague 10.1 TNF TLR6 TLR4 TLR2 IL6
285 obsessive-compulsive disorder 10.1 TNF OXT IL6 IL1B ESR1 CXCL8
286 melioidosis 10.1 TNF TLR4 TLR2 TLR1 IL6
287 testicular disease 10.1 TNF TLR4 TLR2 TLR1 IL6
288 chorioamnionitis 10.1 TNF TLR4 OXT IL6 IL1B CXCL8
289 pulmonary hypertension 10.1 TNF PTGS2 IL6 IL1B CXCL8
290 invasive aspergillosis 10.1 TLR6 TLR4 TLR2 TLR1 CXCL8
291 myocarditis 10.1 TNF TLR4 TLR3 IL6 IL1B
292 influenza 10.1 TNF TLR3 IL6 IL1B CXCL8
293 penile disease 10.1 TNF TLR4 TLR3 TLR2 IL6
294 chlamydia 10.1 TNF TLR4 TLR2 IL6 IL1B CXCL8
295 dental pulp disease 10.0 TNF TLR4 TLR2 IL6 IL1B CXCL8
296 migraine with or without aura 1 10.0 TNF PTGS2 OXT IL6 IL1B ESR1
297 middle ear disease 10.0 TNF TLR4 TLR2 IL6 IL1B CXCL8
298 aphthous stomatitis 10.0 TNF TLR4 TLR2 IL6 IL1B CXCL8
299 stomatitis 10.0 TNF TLR4 TLR2 IL6 IL1B CXCL8
300 aggressive periodontitis 10.0 TNF TLR4 TLR2 IL6 IL1B CXCL8
301 bacterial vaginosis 10.0 TNF TLR4 TLR2 IL6 IL1B CXCL8
302 legionellosis 10.0 TNF TLR4 TLR2 IL6 IL1B CXCL8
303 contact dermatitis 10.0 TNF TLR4 TLR2 IL6 IL1B CXCL8
304 bacterial meningitis 10.0 TNF TLR4 TLR2 IL6 IL1B CXCL8
305 meningitis 10.0 TNF TLR4 TLR2 IL6 IL1B CXCL8
306 alcoholic liver cirrhosis 10.0 TNF TLR4 TLR2 IL6 IL1B CXCL8
307 alcoholic hepatitis 10.0 TNF TLR4 TLR2 IL6 IL1B CXCL8
308 osteomyelitis 10.0 TNF TLR4 TLR2 IL6 IL1B CXCL8
309 corneal disease 10.0 TNF TLR4 TLR2 IL6 IL1B CXCL8
310 toxic shock syndrome 10.0 TNF TLR4 TLR2 IL6 IL1B CXCL8
311 gout 10.0 TNF TLR4 TLR2 IL6 IL1B CXCL8
312 plasmodium falciparum malaria 10.0 TNF IL6 HP
313 bronchitis 10.0 TNF TLR4 TLR2 IL6 IL1B CXCL8
314 peritonitis 10.0 TNF TLR4 TLR2 IL6 IL1B CXCL8
315 gastroesophageal reflux 10.0 TNF PTGS2 IL6 IL1B HP CXCL8
316 pelvic inflammatory disease 10.0 TLR6 TLR4 TLR2 TLR1 MFN2
317 leishmaniasis 10.0 TNF TLR4 TLR2 IL6 IL1B CXCL8
318 cerebral palsy 10.0 TNF TLR4 PTGS2 IL6 IL1B CXCL8
319 cardiovascular system disease 10.0 TNF TLR4 PTGS2 IL6 HP ESR1
320 cystic fibrosis 10.0 TNF TLR4 IL6 IL1B HP CXCL8
321 primary biliary cirrhosis 10.0 TNF TLR4 TLR3 IL6 IL1B
322 mouth disease 10.0 TLR4 TLR3 SIGLEC5 IL6 IL1B ESR1
323 lung disease 10.0 TNF TLR4 TLR2 IL6 IL1B CXCL8
324 skin disease 10.0 TNF TLR4 TLR2 SIGLEC5 IL6 CXCL8
325 fallopian tube disease 10.0 TNF TLR4 TLR2 MFN2 IL6 CXCL8
326 gastric adenocarcinoma 10.0 TNF PTGS2 IL6 IL1B ESR1 CXCL8
327 eye disease 10.0 TNF TLR4 TLR2 IL6 IL1B CXCL8
328 leptospirosis 10.0 TNF TLR2 TLR1 IL6 IL1B CXCL8
329 q fever 10.0 TNF TLR4 TLR2 TLR1 IL6 IL1B
330 bone disease 10.0 TNF SDC1 IL6 IL1B ESR1 CYP19A1
331 toxoplasmosis 10.0 TNF TLR4 TLR2 TLR1 IL6 IL1B
332 superficial basal cell carcinoma 10.0 TLR6 TLR4 TLR3 TLR2 TLR1
333 combat disorder 10.0 TLR6 TLR4 TLR3 TLR2 TLR1
334 anogenital venereal wart 10.0 TLR6 TLR4 TLR3 TLR2 TLR1
335 gingival overgrowth 10.0 TNF IL6 CXCL8
336 vaginal discharge 10.0 OXT IL6 IFI30 HP ESR1 CYP19A1
337 gingival disease 9.9 TNF TLR4 TLR2 SIGLEC5 IL6 IL1B
338 sebaceous gland disease 9.9 TNF TLR4 TLR2 SIGLEC5 IL6 IL1B
339 preterm premature rupture of the membranes 9.9 TNF TLR4 TLR2 OXT IL6 IL1B
340 viral hepatitis 9.9 TNF TLR4 TLR3 TLR2 IL6 HP
341 common cold 9.9 TNF TLR4 TLR3 TLR2 IL6 CXCL8
342 nose disease 9.9 TNF TLR4 TLR3 TLR2 IL6 CXCL8
343 dysentery 9.9 TNF TLR4 TLR2 IL6 IL1B HP
344 bacterial pneumonia 9.9 TNF TLR4 TLR3 TLR2 IL6 CXCL8
345 reactive arthritis 9.9 TNF TLR4 TLR2 IL6 IL1B HP
346 viral encephalitis 9.9 TNF TLR3 PTGS2 IL6 IL1B CXCL8
347 pulmonary disease, chronic obstructive 9.9 TNF TLR4 TLR2 SIGLEC5 IL6 IL1B
348 lyme disease 9.9 TNF TLR6 TLR2 TLR1 IL6 IL1B
349 measles 9.9 TNF TLR4 TLR3 TLR2 IL6 IL1B
350 upper respiratory tract disease 9.9 TNF TLR4 TLR3 TLR2 IL6 CXCL8
351 pancreatic adenocarcinoma 9.9 TNF PTGS2 IL6 ESR1 CXCL8
352 crohn's disease 9.9 TNF TLR4 TLR2 IL6 IL1B HP
353 filariasis 9.9 TNF TLR6 TLR4 TLR2 TLR1 IL6
354 connective tissue disease 9.9 TNF TLR4 TLR2 SIGLEC5 IL6 IL1B
355 muscular disease 9.9 TNF TLR4 MFN2 IL6 IL1B ESR1
356 hepatitis b 9.9 TNF TLR4 TLR3 TLR2 IL6 CXCL8
357 thrombocytopenia 9.9 TNF TLR4 TLR2 IL6 IL1B HP
358 cervical cancer 9.9 TNF TLR4 PTGS2 IL6 ESR1 CXCL8
359 colitis 9.9 TNF TLR4 TLR2 PTGS2 IL6 IL1B
360 peripheral nervous system disease 9.9 TNF TLR4 TLR2 MFN2 IL6 IL1B
361 periodontitis 9.9 TNF TLR4 TLR2 PTGS2 IL6 IL1B
362 pneumonia 9.9 TNF TLR6 TLR4 TLR2 IL6 IL1B
363 chronic mucocutaneous candidiasis 9.9 TNF TLR3 TLR2 TLR1 IL6 IL1B
364 chagas disease 9.8 TNF TLR6 TLR4 TLR2 IL6 IL1B
365 otitis media 9.8 TNF TLR4 TLR2 TLR1 IL6 IL1B
366 endometrial adenocarcinoma 9.8
367 vaginitis 9.8 TNF TLR4 TLR2 SIGLEC5 IL6 IL1B
368 portal hypertension 9.8 TNF TLR4 CXCL8
369 gastritis 9.8 TNF TLR4 PTGS2 PTGES IL6 IL1B
370 myeloma, multiple 9.8 TNF TLR4 TLR3 SDC1 IL6 ESR1
371 conjunctival disease 9.8 TNF TLR4 TLR3 TLR2 IL6 IL1B
372 keratitis, hereditary 9.8 TNF TLR4 TLR3 TLR2 IL6 IL1B
373 candidiasis 9.8 TNF TLR4 TLR3 TLR2 IL6 IL1B
374 chlamydia pneumonia 9.8 TNF TLR6 TLR4 TLR2 TLR1 IL6
375 pulmonary fibrosis, idiopathic 9.8 TNF TLR4 TLR3 TLR2 IL6 IL1B
376 macular degeneration, age-related, 1 9.8 TNF TLR4 TLR3 TLR2 IL6 IL1B
377 multiple sclerosis 9.8 TNF TLR4 TLR3 TLR2 IL6 IL1B
378 trypanosomiasis 9.7 TNF TLR6 TLR4 TLR2 IL6 IL1B
379 extrinsic cardiomyopathy 9.7 TNF TLR4 TLR3 TLR2 TLR1 IL6
380 diabetes mellitus 9.7 TNF TLR4 TLR2 PTGS2 IL6 IL1B
381 anus disease 9.7 TNF TLR4 TLR3 TLR2 TLR1 IL6
382 bacterial sepsis 9.7 TNF TLR4 TLR3 TLR2 TLR1 IL6
383 hydatidiform mole, recurrent, 1 9.7
384 leiomyoma 9.7
385 papillary carcinoma 9.7
386 gestational trophoblastic neoplasm 9.7
387 myofibroma 9.7
388 partial hydatidiform mole 9.7
389 primary peritoneal serous/papillary carcinoma 9.7
390 rheumatoid arthritis 9.7 TNF TLR4 TLR2 PTGS2 IL6 IL1B
391 breast cancer 9.7
392 colorectal cancer 9.7
393 endometriosis 1 9.7
394 progesterone resistance 9.7
395 polycystic ovary syndrome 9.7
396 adenocarcinoma 9.7
397 lynch syndrome 9.7
398 osteoporosis 9.7 TNF TLR4 PTGS2 OXT IL6 IL1B
399 proteasome-associated autoinflammatory syndrome 1 9.7 TNF TLR6 TLR4 TLR2 PTGS2 IL6
400 herpangina 9.6 TNF TLR6 TLR4 TLR3 TLR2 TLR1
401 coccidiosis 9.6 TNF TLR6 TLR4 TLR3 TLR2 TLR1
402 arthritis 9.6 TNF TLR4 TLR2 PTGS2 PTGES IL6
403 myocardial infarction 9.6 TNF TLR4 TLR2 PTGS2 IL6 IL1B
404 commensal bacterial infectious disease 9.6 TNF TLR4 TLR3 TLR2 TLR1 IL6
405 bacterial infectious disease 9.6 TNF TLR4 TLR3 TLR2 TLR1 IL6
406 tonsillitis 9.6 TNF TLR4 TLR3 TLR2 TLR1 IL6
407 autoimmune disease of central nervous system 9.6 TNF TLR4 TLR3 TLR2 TLR1 IL6
408 viral infectious disease 9.6 TNF TLR4 TLR3 TLR2 TLR1 IL6
409 systemic lupus erythematosus 9.5 TNF TLR4 TLR3 TLR2 SDC1 IL6
410 opportunistic mycosis 9.5 TNF TLR6 TLR4 TLR3 TLR2 TLR1
411 rectal disease 9.5 TNF TLR6 TLR4 TLR3 TLR2 TLR1
412 streptococcus pneumonia 9.5 TNF TLR6 TLR4 TLR3 TLR2 TLR1
413 bronchiolitis 9.5 TNF TLR6 TLR4 TLR3 TLR2 TLR1
414 diabetes mellitus, insulin-dependent 9.5 TNF TLR6 TLR4 TLR3 TLR2 TLR1
415 salmonellosis 9.4 TNF TLR6 TLR4 TLR3 TLR2 TLR1
416 autoimmune disease of musculoskeletal system 9.4 TNF TLR6 TLR4 TLR3 TLR2 TLR1
417 celiac disease 1 9.4 TNF TLR6 TLR4 TLR3 TLR2 TLR1
418 perinatal necrotizing enterocolitis 9.4 TNF TLR6 TLR4 TLR3 TLR2 TLR1
419 vaginal disease 9.4 TNF TLR6 TLR4 TLR3 TLR2 TLR1
420 aspergillosis 9.4 TNF TLR6 TLR4 TLR3 TLR2 TLR1
421 leprosy 3 9.4 TNF TLR6 TLR4 TLR3 TLR2 TLR1
422 behcet syndrome 9.4 TNF TLR6 TLR4 TLR3 TLR2 TLR1
423 parasitic protozoa infectious disease 9.3 TNF TLR6 TLR4 TLR3 TLR2 TLR1
424 immune system disease 9.2 TNF TLR6 TLR4 TLR3 TLR2 TLR1
425 bronchial disease 9.2 TNF TLR6 TLR4 TLR3 TLR2 TLR1
426 primary bacterial infectious disease 9.2 TNF TLR6 TLR4 TLR3 TLR2 TLR1
427 dermatitis, atopic 9.2 TNF TLR6 TLR4 TLR3 TLR2 TLR1
428 asthma 9.2 TNF TLR6 TLR4 TLR3 TLR2 TLR1
429 bone inflammation disease 9.2 TNF TLR6 TLR4 TLR3 TLR2 TLR1
430 diabetes mellitus, noninsulin-dependent 9.2 TNF TLR6 TLR4 TLR3 TLR2 TLR1
431 malaria 9.1 TNF TLR6 TLR4 TLR2 TLR1 SDC1
432 inflammatory bowel disease 9.0 TNF TLR6 TLR4 TLR3 TLR2 TLR1
433 hypertension, essential 8.8 TNF TLR6 TLR4 TLR3 TLR2 TLR1
434 body mass index quantitative trait locus 11 8.5 TNF TLR6 TLR4 TLR3 TLR2 TLR1

Graphical network of the top 20 diseases related to Endometrial Disease:



Diseases related to Endometrial Disease

Symptoms & Phenotypes for Endometrial Disease

MGI Mouse Phenotypes related to Endometrial Disease:

45 (showing 17, show less)
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.39 CYP19A1 ERRFI1 ESR1 HP IL1B IL6
2 hematopoietic system MP:0005397 10.39 CYP19A1 ERRFI1 ESR1 HP IL1B IL6
3 immune system MP:0005387 10.38 CYP19A1 ERRFI1 ESR1 HP IFI30 IL1B
4 homeostasis/metabolism MP:0005376 10.37 CYP19A1 ERRFI1 ESR1 HP IL1B IL6
5 behavior/neurological MP:0005386 10.34 CYP19A1 ERRFI1 ESR1 IL6 MFN2 OXT
6 integument MP:0010771 10.23 CYP19A1 ERRFI1 ESR1 IL1B IL6 OXT
7 endocrine/exocrine gland MP:0005379 10.22 CYP19A1 ERRFI1 ESR1 IL6 OXT PTGS2
8 digestive/alimentary MP:0005381 10.19 CYP19A1 ERRFI1 ESR1 IL6 OXT PTGS2
9 adipose tissue MP:0005375 10.17 CYP19A1 ESR1 IL6 OXT PTGS2 TLR2
10 neoplasm MP:0002006 10.11 ERRFI1 ESR1 HP IL1B IL6 PTGS2
11 liver/biliary system MP:0005370 10.09 CYP19A1 ERRFI1 ESR1 HP IL6 PTGS2
12 muscle MP:0005369 10.06 CYP19A1 ESR1 IL6 MFN2 PTGS2 TLR2
13 nervous system MP:0003631 10.06 CYP19A1 ESR1 IL1B IL6 MFN2 OXT
14 renal/urinary system MP:0005367 9.91 CYP19A1 ERRFI1 ESR1 HP IL6 OXT
15 reproductive system MP:0005389 9.9 CYP19A1 ERRFI1 ESR1 IL6 OXT PTGS2
16 respiratory system MP:0005388 9.56 ERRFI1 ESR1 IL6 PTGS2 TLR2 TLR3
17 skeleton MP:0005390 9.32 CYP19A1 ERRFI1 ESR1 IL1B IL6 MFN2

Drugs & Therapeutics for Endometrial Disease

Drugs for Endometrial Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(showing 42, show less)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Mepivacaine Approved, Vet_approved Phase 4 96-88-8 4062
2
Bupivacaine Approved, Investigational Phase 4 38396-39-3, 2180-92-9 2474
3 Anesthetics, Local Phase 4
4 Anesthetics Phase 4
5 Central Nervous System Depressants Phase 4
6 Pharmaceutical Solutions Phase 4
7
Tamoxifen Approved Phase 3 10540-29-1 2733526
8
Medroxyprogesterone acetate Approved, Investigational Phase 3 71-58-9
9
Sodium citrate Approved, Investigational Phase 3 68-04-2
10
Misoprostol Approved Phase 3 59122-46-2 5282381
11
Megestrol acetate Approved, Investigational, Vet_approved Phase 2, Phase 3 595-33-5 11683
12
Levonorgestrel Approved, Investigational Phase 2, Phase 3 797-63-7, 17489-40-6 13109
13
Citric acid Approved, Nutraceutical, Vet_approved Phase 3 77-92-9 311
14 Estrogens Phase 3
15 Citrate Phase 3
16 Selective Estrogen Receptor Modulators Phase 3
17 Hormone Antagonists Phase 3
18 Contraceptive Agents, Male Phase 3
19
Medroxyprogesterone Phase 3 520-85-4 10631
20 Estrogen Antagonists Phase 3
21 Estrogen Receptor Antagonists Phase 3
22 Estrogen Receptor Modulators Phase 3
23 Gastrointestinal Agents Phase 3
24 Oxytocics Phase 3
25 Anti-Ulcer Agents Phase 3
26 Antacids Phase 3
27 Contraceptive Agents Phase 2, Phase 3
28 Contraceptives, Oral Phase 2, Phase 3
29 Antineoplastic Agents, Hormonal Phase 2, Phase 3
30 Hormones Phase 2, Phase 3
31 Central Nervous System Stimulants Phase 2, Phase 3
32
Megestrol Phase 2, Phase 3 3562-63-8 19090 3080587
33 Appetite Stimulants Phase 2, Phase 3
34
Paclitaxel Approved, Vet_approved Phase 2 33069-62-4 36314
35
Lenograstim Approved, Investigational Phase 2 135968-09-1
36
Carboplatin Approved Phase 2 41575-94-4 10339178 498142 38904
37 Immunologic Factors Phase 2
38 Albumin-Bound Paclitaxel Phase 2
39 Antimitotic Agents Phase 2
40 Adjuvants, Immunologic Phase 2
41
protease inhibitors
42 HIV Protease Inhibitors

Interventional clinical trials:

(showing 14, show less)
# Name Status NCT ID Phase Drugs
1 Randomized Double-blind Placebo Controlled Trial to Assess the Role of Intrauterine Cornual Block (ICOB) in Combination With Direct Cervical Block in Outpatient Endometrial Ablation Completed NCT01808898 Phase 4
2 A Randomized Comparison Of Medroxyprogesterone Acetate (MA) And Observation For Prevention Of Endometrial Pathology In Postmenopausal Breast Cancer Patients Treated With Tamoxifen, Phase III Completed NCT00002920 Phase 3 medroxyprogesterone;tamoxifen citrate
3 A Randomized Comparison of Oral, Sublingual and Vaginal Misoprostol Administration in Premenopausal Women Before Operative Hysteroscopy Completed NCT01805115 Phase 3 Oral misoprostol;Sublingual misoprostol;Vaginal misoprostol;Control
4 Megestrol Acetate Plus LNG-IUS to Megestrol Acetate in Young Women With Early Endometrial Cancer Recruiting NCT03241914 Phase 2, Phase 3 Megestrol Acetate
5 Phase II Study of Weekly Paclitaxel/Carboplatin in Combination With Prophylactic G-CSF in the Treatment of Gynaecological Cancers Completed NCT01523678 Phase 2 Filgrastim;Paclitaxel;Carboplatin
6 A Single Arm Phase II Trial of BMN 673 for Inoperable, Advanced Endometrial Cancer With Retrospective PTEN, MSI and MRE11 Analysis Withdrawn NCT02127151 Phase 2 BMN 673
7 Intrauterine Saline Washing for Detection Endometrial Disease in Patients With Abnormal Uterine Bleeding Unknown status NCT02691715
8 Endometrial Volume as a Predictor of Endometrial Pathology in Perimenopausal Uterine Bleeding Endometrial Volume as a Predictor of Endometrial Pathology in Perimenopausal Uterine Bleeding Unknown status NCT03351673
9 REM (Risk Of Endometrial Malignancy): A Proposal for a New Scoring System to Evaluate Risk of Endometrial Malignancy Completed NCT01830192
10 Evaluation of Serum Human Epididymis Secretory Protein 4 (HE4) in Benign Endometrial Disease and Endometrial Cancer Completed NCT03456791
11 Study of Diagnosis of Color Power Doppler Combined Minimally Invasive Sampling for Endometrial Diseases Recruiting NCT03289468
12 HE4 is a Beneficial Biomarker in Endometrial Cancer Recruiting NCT03459976
13 Endometrial and Isthmic Microbiota During IVF Stimulation in Patients Affected With Isthmocele and Intrauterine Mucus Secretion After C-section. Active, not recruiting NCT03519763
14 Low Level Laser Therapy to Endometrial Cells: A Novel Approach to Increase Endometrial Proliferation and Enhance Endometrial Receptivity Available NCT02764034

Search NIH Clinical Center for Endometrial Disease

Genetic Tests for Endometrial Disease

Anatomical Context for Endometrial Disease

The Foundational Model of Anatomy Ontology organs/tissues related to Endometrial Disease:

19
Endometrium

MalaCards organs/tissues related to Endometrial Disease:

40
Breast, Bone, Liver, Ovary, Lymph Node, Eye, Lung

Publications for Endometrial Disease

Articles related to Endometrial Disease:

(showing 185, show less)
# Title Authors PMID Year
1
[Analysis of influencing factors of endometrial disease of patients with breast cancer after operation]. 61
31874475 2019
2
Preoperative platelet morphology parameters as prognostic predictors for endometrial malignant carcinoma stage and progesterone receptor. 61
31764773 2019
3
Patient-derived organoids from endometrial disease capture clinical heterogeneity and are amenable to drug screening. 61
31371824 2019
4
More Than Just 2 Layers: A Comprehensive Multimodality Imaging Review of Endometrial Abnormalities. 61
31307863 2019
5
Cell and biomaterial-based approaches to uterus regeneration. 61
31198582 2019
6
The prognostic significance of positive peritoneal cytology in endometrial cancer and its correlations with L1-CAM biomarker. 61
30851892 2019
7
The Impact of Gynaecological Tumour Board Rounds on Patient Care. 61
30393059 2019
8
Event-free survival following early endometrial events in breast cancer patients treated with anti-hormonal therapy: A nationwide claims data study. 61
30633178 2019
9
The CXL12/CXCR4/CXCR7 axis in female reproductive tract disease: Review. 61
30106199 2018
10
Generation of Progesterone-Responsive Endometrial Stromal Fibroblasts from Human Induced Pluripotent Stem Cells: Role of the WNT/CTNNB1 Pathway. 61
30392973 2018
11
A phase I/II study of GLIF combination chemotherapy for taxane/platinum-refractory/resistant endometrial cancer (GOGO-EM2). 61
30030584 2018
12
Comparison of endometrial assessment by transvaginal ultrasonography and hysteroscopy. 61
29904926 2018
13
Evaluation of complete blood count parameters to predict endometrial cancer. 61
29604099 2018
14
Implementing the Risk of Endometrial Malignancy Algorithm (REM) adding obesity as a predictive factor: Results of REM-B in a single-center survey. 61
29660578 2018
15
Therapeutic strategies involving uterine stem cells in reproductive medicine. 61
29652725 2018
16
Endometrial histopathology results and evaluation of endometrial cancer risk in geriatric women. 61
29725280 2018
17
Metabolomic Signature of Endometrial Cancer. 61
29235868 2018
18
Pathological and molecular diagnosis of bilateral inguinal lymph nodes metastases from low-grade endometrial adenocarcinoma: a case report with review of the literature. 61
29295713 2018
19
Elevated Prevalence of Polycystic Ovary Syndrome and Cardiometabolic Disease in South Asian Infertility Patients. 61
27351893 2017
20
Nuclear factor-κB expression in the endometrium of normal and overweight women with polycystic ovary syndrome. 61
28617068 2017
21
Validation of REM score to predict endometrial cancer in patients with ultrasound endometrial abnormalities: results of a new independent dataset. 61
28389908 2017
22
Evaluating the Age Cutoff Criterion for Reporting Benign-Appearing Endometrial Cells in Routine Pap Tests: An 8-Year Retrospective Review. 61
28486237 2017
23
Quantitative contrast-enhanced ultrasonography for the differential diagnosis of endometrial hyperplasia and endometrial neoplasms. 61
27895728 2016
24
Correlation between Cyr61 expression and clinicopathologic parameters in adenomyosis. 61
27644084 2016
25
Differentiation between endometrial carcinoma and atypical endometrial hyperplasia with transvaginal sonographic elastography. 61
26711550 2016
26
The accuracy of endometrial sampling in women with postmenopausal bleeding: a systematic review and meta-analysis. 61
26748390 2016
27
Stage IVB endometrial cancer confined to the abdomen: is chemotherapy superior to radiotherapy? 61
27172750 2016
28
Could in-vitro studies on Ishikawa cell lines explain the endometrial safety of raloxifene? Systematic literature review and starting points for future oncological research. 61
25536299 2015
29
Endometrial Ablation in Women With Abnormal Uterine Bleeding Related to Ovulatory Dysfunction: A Cohort Study. 61
26149205 2015
30
Potential role of cervicovaginal extracellular particles in diagnosis of endometriosis. 61
26253321 2015
31
Efficacy of the Levonorgestrel-Releasing Intrauterine System on IVF-ET Outcomes in PCOS With Simple Endometrial Hyperplasia. 61
25536958 2015
32
Estrogen receptor β: the guardian of the endometrium. 61
25305176 2015
33
The p160/steroid receptor coactivator family: potent arbiters of uterine physiology and dysfunction. 61
25297546 2014
34
Performance of multidetector CT in the evaluation of the endometrium: Measurement of endometrial thickness and detection of disease. 61
25060929 2014
35
Circulating endometrial cells in peripheral blood. 61
25195200 2014
36
Influence of AKT on progesterone action in endometrial diseases. 61
25100707 2014
37
Recurrent postmenopausal bleeding: a prospective cohort study. 61
24681065 2014
38
Surgical management of early endometrial cancer: an update and proposal of a therapeutic algorithm. 61
25063051 2014
39
Role of hysteroscopy prior to assisted reproduction techniques. 61
24067621 2014
40
Experience and results of office hysteroscopy at a primary hospital. 61
24359051 2014
41
Tissue and circulating microRNA influence reproductive function in endometrial disease. 61
24055529 2013
42
Abnormal vaginal bleeding following pharmacist prescribing of metformin leads to the detection of complex endometrial hyperplasia. 61
24285770 2013
43
Histopathologic assessment of the entire endometrium in asymptomatic women. 61
23938162 2013
44
REM (risk of endometrial malignancy): a proposal for a new scoring system to evaluate risk of endometrial malignancy. 61
23983254 2013
45
Mesenchymal stem/progenitors and other endometrial cell types from women with polycystic ovary syndrome (PCOS) display inflammatory and oncogenic potential. 61
23824412 2013
46
Cancer risk and PCOS. 61
23624028 2013
47
Endometrial surveillance in tamoxifen users: role, timing and accuracy of hysteroscopic investigation: observational longitudinal cohort study. 61
23629476 2013
48
Angiogenesis, lymphangiogenesis and neurogenesis in endometriosis. 61
23747918 2013
49
Development of endometrial carcinoma in a patient with leprechaunism (donohue syndrome). 61
23990696 2013
50
Laparoendoscopic single-site surgery with hysterectomy in patients with prior cesarean section: comparison of surgical outcomes with bladder dissection techniques. 61
23317681 2013
51
Effect of tamoxifen on postmenopausal endometrium. 61
24020139 2013
52
[Tamoxifen and endometrial disease in patients with breast cancer]. 61
23570756 2013
53
Baseline hysteroscopic assessment of endometrium in asymptomatic postmenopausal women with estrogen receptor-positive breast cancer. 61
22968254 2013
54
Perturbed sperm-epithelial interaction in bitches with mating-induced endometritis. 61
22721627 2012
55
Capacity of endometrial thickness measurement to diagnose endometrial carcinoma in asymptomatic postmenopausal women: a systematic review and meta-analysis. 61
23001905 2012
56
Diffusion-weighted magnetic resonance imaging of the normal endometrium: temporal and spatial variations of the apparent diffusion coefficient. 61
22619357 2012
57
New challenges in detecting, grading, and staging endometrial cancer after uterine morcellation. 61
22417903 2012
58
[Clinical function of estrogen receptors in endometrial cancer]. 61
22036754 2011
59
ACR appropriateness criteria(®) on abnormal vaginal bleeding. 61
21723482 2011
60
Cigarette smoke increases progesterone receptor and homeobox A10 expression in human endometrium and endometrial cells: a potential role in the decreased prevalence of endometrial pathology in smokers. 61
21325691 2011
61
Akt/protein B and estradiol receptor alpha expressions in postmenopausal endometrium. 61
21295396 2011
62
Regulatory T cells and other leukocytes in the pathogenesis of endometriosis. 61
21269709 2011
63
Cervical polyps: evaluation of routine removal and need for accompanying D&C. 61
20213130 2011
64
Endometrial histology and predictable clinical factors for endometrial disease in women with polycystic ovary syndrome. 61
22384417 2011
65
Automatic measurement of volume percentage stroma in endometrial images using texture segmentation. 61
21118212 2011
66
Dienogest, a synthetic progestin, inhibits prostaglandin E2 production and aromatase expression by human endometrial epithelial cells in a spheroid culture system. 61
20851710 2011
67
Genome-based expression profiling as a single standardized microarray platform for the diagnosis of endometrial disorder: an array of 126-gene model. 61
19328470 2010
68
Progesterone resistance and endometrial disease. Preface. 61
20104423 2010
69
Gene transcription of TLR2, TLR4, LPS ligands and prostaglandin synthesis enzymes are up-regulated in canine uteri with cystic endometrial hyperplasia-pyometra complex. 61
19945173 2010
70
[Early diagnosis of endometrial disorder in women with postmenopausal bleeding by three-dimensional transvaginal sonography and hysterosonography]. 61
20017326 2009
71
Mig-6 modulates uterine steroid hormone responsiveness and exhibits altered expression in endometrial disease. 61
19439667 2009
72
Saline-infusion sonography endometrial sampling compared with endometrial biopsy in diagnosing endometrial pathology. 61
19305334 2009
73
Uterine tumor resembling ovarian sex cord tumors treated by resectoscopic surgery. 61
19249718 2009
74
Three-dimensional power Doppler ultrasound scanning for the prediction of endometrial cancer in women with postmenopausal bleeding and thickened endometrium. 61
18976731 2009
75
Performance of office hysteroscopy and endometrial biopsy for detecting endometrial disease in women at risk of human non-polyposis colon cancer: a prospective study. 61
18217965 2008
76
Comparative effects of estradiol, methyl-piperidino-pyrazole, raloxifene, and ICI 182 780 on gene expression in the murine uterus. 54
18632874 2008
77
Canine and feline abortion diagnostics. 61
18541293 2008
78
Biopsy histomorphometry predicts uterine myoinvasion by endometrial carcinoma: a Gynecologic Oncology Group study. 61
18436277 2008
79
Evaluation of the sensitivity, specificity, positive and negative predictive values of preoperative magnetic resonance imaging for staging endometrial cancer. A prospective study of 100 cases at the Dorset Cancer Centre. 61
17537566 2008
80
[The importance of sonography and hysteroscopy at suspected findings on endometrium of menopausal women]. 61
18567430 2008
81
What is the best method of detecting endometrial cancer in outpatients?-endometrial sampling, suction curettage, endometrial cytology. 61
17944955 2008
82
TV sonographic assessment in postmenopausal women with bleeding. 61
18386468 2008
83
Endometrial hyperplasia and carcinoma in endometrial polyps: clinicopathologic and follow-up findings. 61
18156974 2008
84
The use of non-three-layer ultrasound in biopsy recommendation for premenopausal women. 61
18956267 2008
85
The role of Pipelle Mark II sampling in endometrial disease diagnosis. 61
17029754 2007
86
Endometrial disorders in patients with peritoneal serous papillary carcinoma. 61
16860923 2007
87
Can 19-nortestosterone derivatives be aromatized in the liver of adult humans? Are there clinical implications? 61
17653961 2007
88
Total laparoscopic hysterectomy with and without lymph node dissection for uterine neoplasia. 61
17630162 2007
89
Magnetic resonance imaging of endometrial cancer and clear cell cancer. 61
17414759 2007
90
TV sonographic assessment in postmenopausal asymptomatic women. 61
18179139 2007
91
[Role of hydrosonography in prevention and screening of premalignant and malignant endometrial disease]. 61
17304766 2006
92
Expression and activation of mitogen-activated protein kinase in the human endometrium during the menstrual cycle. 61
16796978 2006
93
Laparoscopic-assisted vaginal hysterectomy versus abdominal hysterectomy in endometrial cancer. 61
16631176 2006
94
Hysteroscopic surgery. 61
16426895 2006
95
Reproducibility of endometrial vascular patterns in endometrial disease as assessed by transvaginal power Doppler sonography in women with postmenopausal bleeding. 61
16439778 2006
96
The significance of benign endometrial cells in cervicovaginal smears. 61
16210924 2005
97
Altered extent, pattern and characteristics of microvascular density are indicators of neoplastic progression in the endometrium. 61
15723304 2005
98
Routine office hysteroscopy in the investigation of infertile couples before assisted reproduction. 61
16130847 2005
99
Accuracy of transvaginal ultrasound in diagnosing endometrial pathology in women with post-menopausal bleeding on tamoxifen. 61
15845930 2005
100
Role of hysteroscopy with endometrial biopsy to rule out endometrial cancer in postmenopausal women with abnormal uterine bleeding. 61
15653009 2005
101
The case for less-than-monthly progestogen in women on HT: is transvaginal ultrasound the key? 61
15668608 2005
102
Transvaginal ultrasonography of the endometrium in postmenopausal Japanese women. 61
16103680 2005
103
Expression of the type I interferon receptor and the interferon-induced Mx protein in human endometrium during the menstrual cycle. 61
15652903 2005
104
Clinical inquiries. Can transvaginal ultrasound detect endometrial disease among asymptomatic postmenopausal patients? 61
15581447 2004
105
Outpatient hysteroscopy and ultrasonography in the management of endometrial disease. 61
15232484 2004
106
Is pipelle biopsy really adequate for diagnosing endometrial disease? 61
15173672 2004
107
Ultrasonography and cystic hyperplasia-pyometra complex in the bitch. 61
15182288 2004
108
Cystic endometrial hyperplasia in elephants. 61
15017033 2004
109
[Fertility: hysteroscopic features and endometrial disease]. 61
14988984 2003
110
Assessment of abnormal bleeding in menopausal women: an update. 61
14670197 2003
111
Comparison of hysteroscopic and hysterectomy findings to assess the diagnostic accuracy of office hysteroscopy in tamoxifen-treated patients with breast cancer. 61
14567820 2003
112
Alteration of G2 cell cycle regulators occurs during carcinogenesis of the endometrium. 61
12931023 2003
113
Accuracy of hysteroscopy in the diagnosis of endometrial cancer and hyperplasia: a systematic quantitative review. 61
12350192 2002
114
Inguinal lymph node metastasis as the presenting symptom of endometrial cancer: a case report. 61
12174957 2002
115
Endometrial hyperplasia and mineralization in zoo felids treated with melengestrol acetate contraceptives. 61
12126144 2002
116
Screening transvaginal uterine ultrasonography for identifying endometrial pathology in postmenopausal women. 61
12174954 2002
117
Evaluation of outpatient hysteroscopy and ultrasonography in the diagnosis of endometrial disease. 61
12052590 2002
118
Diagnosis of premalignant endometrial disease. 61
11986334 2002
119
Postmenopausal bleeding: value of imaging. 61
12117192 2002
120
Transvaginal uterine ultrasonography compared with endometrial biopsy for the detection of endometrial disease in perimenopausal women with uterine bleeding. 61
12168877 2002
121
Angiogenic co-operation of VEGF and stromal cell TP in endometrial carcinomas. 61
11920737 2002
122
Screening transvaginal uterine ultrasonography for identifying endometrial pathology in postmenopausal women. 61
12168911 2002
123
Role of aromatase in endometrial disease. 61
11850203 2001
124
Imaging the endometrium: disease and normal variants. 61
11706213 2001
125
Angiogenesis and endometrial cancer. 61
11908694 2001
126
Normal endometrial cells in Papanicolaou smears: prevalence in women with and without endometrial disease. 61
11354070 2001
127
Significance of "normal" endometrial cells in cervical cytology from asymptomatic postmenopausal women receiving hormone replacement therapy. 61
11277646 2001
128
Significance of cytologically normal endometrial cells in cervical smears from postmenopausal women. 61
11284298 2001
129
An assessment of the value of ultrasonographic screening for endometrial disease in postmenopausal women without symptoms. 61
11174482 2001
130
Cytologically benign endometrial cells in the papanicolaou smears of postmenopausal women. 61
11136567 2001
131
Normal endometrial cells in Papanicolaou smears: prevalence in women with and without endometrial disease. 61
11084170 2000
132
Temporal changes in clinic and ambulatory blood pressure during cyclic post-menopausal hormone replacement therapy. 61
11057425 2000
133
Is endometriosis an endometrial disease? 61
10869783 2000
134
[Value of MR imaging in the diagnosis of benign uterine conditions]. 61
10915990 2000
135
The significance of atypical glandular cells on routine cervical cytologic testing in a community-based population. 61
10871439 2000
136
Sporadic microsatellite instability is specific to neoplastic and preneoplastic endometrial tissues. 61
10787358 2000
137
Endometrial intraepithelial neoplasia (EIN): will it bring order to chaos? The Endometrial Collaborative Group. 61
10684697 2000
138
Assessment of hypermethylated DNA in two promoter regions of the estrogen receptor alpha gene in human endometrial diseases. 61
10620447 2000
139
Reporting normal endometrial cells in Pap smears: an outcome appraisal. 61
10479497 1999
140
Interleukin-8 stimulates the adhesion of endometrial stromal cells to fibronectin. 61
10439007 1999
141
Endometrial thickness in tamoxifen-treated patients: an independent predictor of endometrial disease. 61
10362171 1999
142
Endometrial disease diagnosed by transvaginal ultrasound and dilatation and curettage. 61
10326888 1999
143
Prediction of benign and malignant endometrial disease: hysterosonographic-pathologic correlation. 61
10207420 1999
144
Ultrasonographic evaluation of endometrial disease in postmenopausal patients with breast cancer and tamoxifen treatment. 61
9914614 1999
145
Intratumoral angiogenesis: a new prognostic indicator for stage I endometrial adenocarcinomas? 61
10566619 1999
146
Endovaginal ultrasound to exclude endometrial cancer and other endometrial abnormalities. 61
9809732 1998
147
Expression of cytokeratin-20 in endometrial carcinoma. 61
9790796 1998
148
Interleukin-8 in the human endometrium. 61
9589693 1998
149
Cervical cytology in menopausal women at high risk for endometrial disease. 61
9818777 1998
150
Transvaginal ultrasonography compared with endometrial biopsy for the detection of endometrial disease. Postmenopausal Estrogen/Progestin Interventions Trial. 61
9400035 1997
151
Prospective study to compare endometrial cytology and transvaginal ultrasonography for identification of endometrial malignancies. 61
9190961 1997
152
Growth-regulated alpha expression in the peritoneal environment with endometriosis. 61
8942852 1996
153
A comparative study of risk factors for hyperplasia and cancer of the endometrium. 61
8736077 1996
154
Combination of vaginal ultrasonography and pipelle sampling in the diagnosis of endometrial disease. 61
8775255 1996
155
Endopap-versus Pipelle-sampling in the diagnosis of postmenopausal endometrial disease. 61
8801158 1996
156
Hormones and breast and endometrial cancers: preventive strategies and future research. 61
8741781 1995
157
Major outer membrane protein variants of Chlamydia trachomatis are associated with severe upper genital tract infections and histopathology in San Francisco. 61
7561174 1995
158
Combining vaginal ultrasonography and office endometrial sampling in the diagnosis of endometrial disease in postmenopausal women. 61
7617370 1995
159
What is the role of hysteroscopy in the management of abnormal uterine bleeding? 61
7554600 1995
160
[Pre-therapeutic management and surveillance of menopausal hormone replacement therapy]. 61
7644873 1995
161
[Diagnostic accuracy in transvaginal echography in benign endometrial diseases and its comparison with hysteroscopic biopsy]. 61
7630511 1995
162
Combining vaginal ultrasonography and office endometrial sampling in the diagnosis of endometrial disease in postmenopausal women. 61
7862370 1995
163
Changes in the withdrawal bleeding pattern and endometrial histology during 17 beta-estradiol-dydrogesterone therapy in postmenopausal women: a 2 year prospective study. 61
7715470 1994
164
Vaginal ultrasonography in the diagnosis of postmenopausal endometrial disease. 61
7809789 1994
165
Transvaginal ultrasonography in the diagnosis of diffuse adenomyosis. 61
1624029 1992
166
The effect of age and parity on the development of equine chronic endometrial disease. 61
1884699 1991
167
Classification of endometrial cells on cervical cytology. 61
2234706 1990
168
Cervical os obliteration after laser surgery in patients with amenorrhea. 61
2359572 1990
169
Endocervical curettage by Vabra aspiration as part of colposcopic evaluation. 61
2318439 1990
170
Significance of normal endometrial cells detected by cervical cytology. 61
3336559 1988
171
Significance of atypical endometrial cells detected by cervical cytology. 61
3574808 1987
172
Serum sex hormone binding globulin (SHBG), testosterone/SHBG index, endometrial pathology and bone mineral density in postmenopausal women. 61
3425232 1987
173
Influence of the histologic and cytologic grade and the clinical and postsurgical stage on the rate of endometrial carcinoma detection by cervical cytology. 61
3466497 1986
174
Conversion of estrone to estradiol and estradiol to estrone in postmenopausal women. 61
3160986 1985
175
Effect of progesterone administration on rat endometrial disease after exposure to N-nitrosomethylurea. 61
6891937 1982
176
Uterine lavage in the diagnosis of endometrial malignancy and its precursors. 61
6952713 1982
177
[Endometrial disease after treatment with oestrogens and progestogens in the climateric (author's transl)]. 61
12336894 1981
178
Endometrial disease after treatment with oestrogens and progestogens in the climacteric. 61
7370682 1980
179
Prevention and treatment of endometrial disease in climacteric women receiving oestrogen therapy. 61
89511 1979
180
Effect of obesity on conversion of plasma androstenedione to estrone in postmenopausal women with and without endometrial cancer. 61
629289 1978
181
Vacuum aspiration: an efficient outpatient screening technic for endometrial disease. 61
850801 1977
182
Diagnostic suction curettage without anesthesia. An investigation into the practical usefulness of the Vabra aspirator. 61
267409 1977
183
[The morphological and histochemical aspects of the endometrial disease caused by the administration of estrogenic and chorionic hormones]. 61
13691903 1961
184
[Functional hemorrhagic endometrial disease; considerations on its treatment]. 61
13324286 1956
185
[Functional hemorrhagic endometrial disease; considerations on its treatment]. 61
13255956 1955

Variations for Endometrial Disease

Expression for Endometrial Disease

Search GEO for disease gene expression data for Endometrial Disease.

Pathways for Endometrial Disease

Pathways related to Endometrial Disease according to GeneCards Suite gene sharing:

(showing 67, show less)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
14.09 TNF TLR6 TLR4 TLR3 TLR2 TLR1
2
Show member pathways
13.47 TNF TLR6 TLR4 TLR3 TLR2 TLR1
3
Show member pathways
13.26 TNF TLR6 TLR4 TLR3 TLR2 TLR1
4
Show member pathways
13.2 TNF TLR6 TLR4 TLR3 TLR2 TLR1
5
Show member pathways
13.04 TNF TLR4 TLR3 TLR2 PTGS2 IL6
6
Show member pathways
13.02 TNF TLR4 TLR3 TLR2 PTGS2 IL6
7
Show member pathways
12.91 TNF TLR4 TLR3 TLR2 IL6 IL1B
8
Show member pathways
12.88 TNF IL6 IL1B IFI30 CXCL8
9
Show member pathways
12.84 TNF TLR4 TLR3 IL6 IL1B CXCL8
10 12.83 TNF TLR3 TLR2 IL6 IL1B
11
Show member pathways
12.77 TNF TLR6 TLR4 TLR3 TLR2 TLR1
12
Show member pathways
12.67 TNF TLR6 TLR4 TLR3 TLR2 TLR1
13
Show member pathways
12.65 TNF TLR4 TLR2 IL6 IL1B
14
Show member pathways
12.65 TNF TLR4 TLR2 IL6 IL1B
15 12.64 TNF TLR6 TLR3 TLR2 TLR1 PTGS2
16
Show member pathways
12.48 TLR6 TLR4 TLR3 TLR2 TLR1
17
Show member pathways
12.44 TNF TLR2 PTGS2 IL6 IL1B CXCL8
18 12.41 TNF TLR4 IL1B CXCL8
19 12.39 TNF TLR4 TLR2 SDC1 ESR1
20 12.38 TNF TLR4 IL6 IL1B CXCL8
21
Show member pathways
12.36 TNF PTGS2 IL6 IL1B
22
Show member pathways
12.34 TNF TLR4 TLR2 PTGS2 IL1B
23 12.34 TNF TLR4 MFN2 IL6 IL1B CXCL8
24
Show member pathways
12.33 TNF TLR4 TLR3 SDC1 PTGS2 IL6
25
Show member pathways
12.31 TNF TLR2 PTGS2 IL6 IL1B CXCL8
26
Show member pathways
12.26 TNF TLR4 TLR3 IL1B
27
Show member pathways
12.26 TNF PTGS2 IL6 IL1B
28 12.26 TNF TLR6 TLR4 TLR2 TLR1 IL6
29
Show member pathways
12.25 TNF TLR6 TLR4 TLR3 TLR2 TLR1
30 12.23 TNF IL6 IL1B CXCL8
31 12.14 TNF TLR6 TLR4 TLR3 TLR2 TLR1
32 12.12 TNF TLR4 IL6 IL1B CXCL8
33
Show member pathways
12.11 TLR6 TLR4 TLR3 TLR2 TLR1 IL1B
34 12.1 TNF PTGS2 IL6 IL1B CXCL8
35
Show member pathways
12.08 TNF TLR6 TLR4 TLR2 TLR1 IL6
36 12.07 TNF TLR4 PTGS2 IL6 IL1B CXCL8
37 12.05 TNF PTGS2 IL6 IL1B
38 12.04 TNF TLR4 PTGS2 IL1B CXCL8
39 11.99 TNF IL6 IL1B CXCL8
40 11.98 TNF TLR4 TLR2 IL6 IL1B CXCL8
41 11.94 TLR6 TLR4 TLR3 TLR2 TLR1
42 11.92 TNF TLR4 TLR2 IL6 IL1B CXCL8
43 11.88 TLR4 IL6 IL1B CXCL8
44
Show member pathways
11.87 TNF TLR6 TLR4 TLR3 TLR2 TLR1
45 11.85 TNF TLR4 IL6 IL1B CXCL8
46 11.82 TNF PTGS2 IL6 IL1B
47
Show member pathways
11.79 TNF PTGS2 CXCL8
48 11.78 TNF IL6 IL1B
49 11.76 TNF IL6 IL1B CXCL8
50
Show member pathways
11.76 TNF PTGS2 IL6 IL1B CXCL8
51
Show member pathways
11.66 TNF TLR6 TLR4 TLR2 TLR1 SDC1
52 11.64 TNF TLR4 TLR2 IL1B
53 11.64 TNF TLR4 TLR2 IL6 IL1B CXCL8
54 11.61 PTGS2 IL6 CXCL8
55 11.61 TNF PTGS2 IL6 IL1B CXCL8
56 11.6 TNF IL6 IL1B CYP19A1
57 11.58 TNF PTGS2 ESR1
58 11.58 TNF IL6 HP
59 11.48 TNF TLR4 IL6 IL1B
60 11.45 TNF IL6 IL1B
61 11.38 TNF IL6 IL1B
62 11.37 TNF IL6 IL1B
63 11.33 TNF IL6 IL1B
64 11.26 TLR2 TLR1 IL1B
65 11.15 TNF PTGS2 IL6 CXCL8
66 10.87 TNF TLR4 TLR2 SDC1 IL6 IL1B
67 10.31 ESR1 CYP19A1

GO Terms for Endometrial Disease

Cellular components related to Endometrial Disease according to GeneCards Suite gene sharing:

(showing 3, show less)
# Name GO ID Score Top Affiliating Genes
1 membrane raft GO:0045121 9.46 TNF TLR6 TLR2 TLR1
2 phagocytic vesicle membrane GO:0030670 9.13 TLR6 TLR2 TLR1
3 Toll-like receptor 1-Toll-like receptor 2 protein complex GO:0035354 8.62 TLR2 TLR1

Biological processes related to Endometrial Disease according to GeneCards Suite gene sharing:

(showing 77, show less)
# Name GO ID Score Top Affiliating Genes
1 signal transduction GO:0007165 10.32 TLR6 TLR4 TLR3 TLR2 TLR1 PTGES
2 positive regulation of transcription by RNA polymerase II GO:0045944 10.28 TNF TLR4 TLR3 TLR2 IL6 IL1B
3 negative regulation of cell proliferation GO:0008285 10.15 TLR2 PTGS2 PTGES IL6 IL1B CXCL8
4 positive regulation of gene expression GO:0010628 10.12 TNF TLR6 TLR4 TLR3 TLR2 IL6
5 immune response GO:0006955 10.1 TNF TLR6 TLR4 TLR2 TLR1 IL6
6 defense response to bacterium GO:0042742 10.09 TNF TLR6 TLR4 TLR3 HP
7 cytokine-mediated signaling pathway GO:0019221 10.07 TNF SDC1 PTGS2 IL6 IL1B CXCL8
8 positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 10.04 TNF TLR6 TLR4 TLR3 IL1B
9 cellular response to lipopolysaccharide GO:0071222 10.04 TNF TLR4 IL6 IL1B CXCL8
10 response to lipopolysaccharide GO:0032496 10.03 TLR4 TLR2 PTGS2 PTGES IL1B
11 defense response GO:0006952 10.03 TNF TLR3 TLR1 HP CXCL8
12 positive regulation of DNA-binding transcription factor activity GO:0051091 10.01 TNF IL6 IL1B ESR1
13 response to organic substance GO:0010033 9.97 TNF SDC1 PTGS2 HP
14 positive regulation of JNK cascade GO:0046330 9.96 TNF TLR4 TLR3 IL1B
15 regulation of inflammatory response GO:0050727 9.96 TNF TLR4 PTGS2 ESR1
16 cellular response to mechanical stimulus GO:0071260 9.96 TLR4 TLR3 PTGS2 IL1B
17 I-kappaB kinase/NF-kappaB signaling GO:0007249 9.92 TNF TLR4 TLR3
18 apoptotic signaling pathway GO:0097190 9.92 TNF TLR4 TLR3
19 positive regulation of smooth muscle cell proliferation GO:0048661 9.91 TNF PTGS2 IL6
20 positive regulation of inflammatory response GO:0050729 9.91 TNF TLR4 TLR3 TLR2 IL1B
21 positive regulation of tumor necrosis factor production GO:0032760 9.9 TLR4 TLR3 TLR2
22 positive regulation of interferon-gamma production GO:0032729 9.9 TNF TLR4 IL1B
23 TRIF-dependent toll-like receptor signaling pathway GO:0035666 9.88 TLR6 TLR4 TLR3
24 positive regulation of vascular endothelial growth factor production GO:0010575 9.88 PTGS2 IL6 IL1B
25 response to glucocorticoid GO:0051384 9.88 TNF SDC1 PTGS2 OXT IL6
26 negative regulation of neurogenesis GO:0050768 9.87 TNF IL6 IL1B
27 positive regulation of interleukin-12 production GO:0032735 9.87 TLR4 TLR3 TLR2
28 positive regulation of interferon-beta production GO:0032728 9.87 TLR4 TLR3