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MCID: END003
MIFTS: 26

Endometrial Stromal Nodule

Categories: Cancer diseases, Reproductive diseases
Genes Tissues Related diseases Publications
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Aliases & Classifications for Endometrial Stromal Nodule

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MalaCards integrated aliases for Endometrial Stromal Nodule:

Name: Endometrial Stromal Nodule 12 15 17 71

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Reproductive diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:1373
NCIt 50 C4262
SNOMED-CT 67 189810002
UMLS 71 C0334485
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Summaries for Endometrial Stromal Nodule

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Disease Ontology : 12 An uterine benign neoplasm that has material basis in cells reminiscent of proliferative phase endometrial stroma.

MalaCards based summary : Endometrial Stromal Nodule is related to mixed endometrial stromal and smooth muscle tumor and endometrial stromal tumor. An important gene associated with Endometrial Stromal Nodule is JAZF1 (JAZF Zinc Finger 1). Affiliated tissues include smooth muscle, skeletal muscle and uterus.

Wikipedia : 74 An endometrial stromal nodule is a noninfiltrative, circumscribed proliferation of endometrial stromal... more...

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Related Diseases for Endometrial Stromal Nodule

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Diseases related to Endometrial Stromal Nodule via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 53)
# Related Disease Score Top Affiliating Genes
1 mixed endometrial stromal and smooth muscle tumor 29.7 MME CALD1
2 endometrial stromal tumor 27.1 ZC3H7B ZC3H7A YWHAE SUZ12 PHF1 NUTM2A
3 endometrial stromal sarcoma 26.6 ZC3H7B ZC3H7A YWHAE SUZ12 PHF1 NUTM2A
4 leiomyoma 10.2
5 rare tumor 10.2
6 meningioma, familial 10.0
7 spinal meningioma 10.0
8 cystadenoma 10.0
9 endometriosis 10.0
10 ovarian cystadenoma 10.0
11 secretory meningioma 10.0
12 lymphoplasmacyte-rich meningioma 10.0
13 ovarian serous cystadenocarcinoma 10.0
14 heart sarcoma 10.0 ZC3H7B MEAF6 JAZF1
15 kidney clear cell sarcoma 9.9 ZC3H7B YWHAE
16 adenosarcoma 9.9 PHF1 MME JAZF1
17 vaginal endometrial stromal tumor 9.8 MME CALD1
18 smooth muscle tumor 9.8 MME CALD1
19 fallopian tube leiomyoma 9.8 MME CALD1
20 urethra leiomyoma 9.8 MME CALD1
21 fallopian tube benign neoplasm 9.8 MME CALD1
22 breast myofibroblastoma 9.8 MME CALD1
23 subareolar duct papillomatosis 9.8 MME CALD1
24 lung combined type small cell carcinoma 9.8 MME CALD1
25 cervical mucinous adenocarcinoma 9.8 MME CALD1
26 nipple benign neoplasm 9.8 MME CALD1
27 cervical polyp 9.7 MME CALD1
28 intravenous leiomyomatosis 9.7 MME CALD1
29 ossifying fibromyxoid tumor 9.7 ZC3H7B PHF1 MEAF6 MBTD1
30 sarcomatoid squamous cell skin carcinoma 9.7 MME CALD1
31 uterus perivascular epithelioid cell tumor 9.7 MME CALD1
32 perivascular epithelioid cell tumor 9.7 MME CALD1
33 vulvar leiomyoma 9.7 MME CALD1
34 atypical polypoid adenomyoma 9.7 MME CALD1
35 adenomyoma 9.7 MME CALD1
36 urethral benign neoplasm 9.7 MME CALD1
37 cervical adenoma malignum 9.7 MME CALD1
38 vaginal cancer 9.7 MME CALD1
39 vulvar benign neoplasm 9.6 MME CALD1
40 ovarian sex-cord stromal tumor 9.6 ZC3H7B SUZ12 MME JAZF1
41 uterine benign neoplasm 9.6 MME JAZF1 CALD1
42 reproductive organ benign neoplasm 9.6 MME JAZF1 CALD1
43 sweat gland benign neoplasm 9.6 MME CALD1
44 mixed cell type cancer 9.5 MME CALD1
45 mesenchymal cell neoplasm 9.5 ZC3H7B MME CALD1
46 cellular leiomyoma 9.5 SUZ12 MME JAZF1 CALD1
47 cervical adenosarcoma 9.5 SUZ12 MME JAZF1 CALD1
48 connective tissue benign neoplasm 9.4 MME CALD1
49 ovarian endometrioid stromal sarcoma 9.3 YWHAE SUZ12 PHF1 MME CALD1
50 ovary sarcoma 9.3 YWHAE SUZ12 PHF1 MME CALD1

Graphical network of the top 20 diseases related to Endometrial Stromal Nodule:



Diseases related to Endometrial Stromal Nodule
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Symptoms & Phenotypes for Endometrial Stromal Nodule

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Drugs & Therapeutics for Endometrial Stromal Nodule

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Search Clinical Trials , NIH Clinical Center for Endometrial Stromal Nodule

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Genetic Tests for Endometrial Stromal Nodule

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Anatomical Context for Endometrial Stromal Nodule

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MalaCards organs/tissues related to Endometrial Stromal Nodule:

40
Smooth Muscle, Skeletal Muscle, Uterus, Placenta, Breast, Ovary
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Publications for Endometrial Stromal Nodule

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Articles related to Endometrial Stromal Nodule:

(show all 46)
# Title Authors PMID Year
1
Detection of MEAF6-PHF1 translocation in an endometrial stromal nodule. 61
32820570 2020
2
Uterine Endometrial Stromal Tumors With Limited Infiltration: First Report of a Case Series Indicating Potential for Malignant Behavior. 61
30807369 2020
3
Recent advances in the histological and molecular classification of endometrial stromal neoplasms. 61
30324234 2018
4
Recurrence after fertility-preserving surgery for low-grade endometrial stromal sarcoma. 61
29974555 2018
5
Endometrial stromal sarcomas and related neoplasms: new developments and diagnostic considerations. 61
29275929 2018
6
Endometrial Stromal Neoplasm in the Placenta: Report of a Case and Review of the Literature. 61
28914670 2018
7
Analysis of diagnosis and treatment of complicated cervical severe adhesion atresia after removal of endometrial stromal nodule: A case report. 61
29310409 2017
8
Uterine sarcoma Part II-Uterine endometrial stromal sarcoma: The TAG systematic review. 61
27590366 2016
9
Hyperhaploid uterine mesenchymal tumors-a novel genetic subgroup? 61
27397601 2016
10
Magnetic resonance imaging of an endometrial stromal nodule. 61
26461974 2016
11
Genomic characterization of endometrial stromal sarcomas with array comparative genomic hybridization. 61
25758203 2015
12
Endometrial stromal tumours revisited: an update based on the 2014 WHO classification. 61
25595274 2015
13
Diffusion-Weighted MRI and FDG-PET in Diagnosis of Endometrial Stromal Nodule. 61
25694838 2015
14
Endometrial stromal nodule of the vaginal wall with a review of vulvovaginal endometrial stromal neoplasms. 61
26076086 2015
15
Endometrial Stromal Nodule: A Rarity and a Pathological Challenge. 61
26221551 2015
16
Endometrial stromal nodule - a case report. 61
25725687 2015
17
Synchronous occurrence of endometrial stromal nodule with papillary serous carcinoma of ovary: report of a case and brief review of literature. 61
25404842 2014
18
Mixed stromal and smooth muscle tumours of the uterus: a report of two cases. 61
25845049 2014
19
Endometrial stromal tumors: the new WHO classification. 61
25299308 2014
20
Malignant potential of endometrial stromal tumor with limited infiltration: a case report. 61
24155223 2014
21
Targeted development of specific biomarkers of endometrial stromal cell differentiation using bioinformatics: the IFITM1 model. 61
24072182 2014
22
Colonic low-grade endometrial stromal sarcoma and orthotopic endometrial stromal tumor with limited infiltration sharing the JAZF1-SUZ12 gene fusion. 61
24750188 2014
23
Successful pregnancy following conservative management of low-grade endometrial stromal sarcoma: A case report. 61
24944665 2014
24
Low grade endometrial stromal sarcoma in a premenopausal woman. 61
24678233 2014
25
Diagnosis of endometrial stromal tumors: a clinicopathologic study of 25 biopsy specimens with identification of problematic areas. 61
24343747 2014
26
Prognostic value of the diagnostic criteria distinguishing endometrial stromal sarcoma, low grade from undifferentiated endometrial sarcoma, 2 entities within the invasive endometrial stromal neoplasia family. 61
23545579 2013
27
[Myxoid mesenchymal tumors of uterus: endometrial stromal and smooth muscle tumors, myxoid variant]. 61
21736994 2011
28
Cytogenetic and molecular aberrations in endometrial stromal tumors. 61
21420714 2011
29
Endometrial stromal nodule: report of a case. 61
21423543 2011
30
[A rare tumor: endometrial stromal nodule]. 61
21178883 2010
31
Endometrial stromal sarcomas: a review of potential prognostic factors. 61
20179433 2010
32
Endometrial stromal lesions: a morphological and immunohistochemical study of short series. 61
17619891 2008
33
Endometrial stromal nodule with smooth muscle differentiation. 61
18417866 2008
34
Endometrial stromal nodule embedded into term placenta. 61
18092965 2007
35
Meningioma-like endometrial stromal nodule with a stromal-derived foam cell component. 61
16918981 2006
36
Utility of MIB-1 and estrogen and progesterone receptor in distinguishing between endometrial stromal sarcomas and endometrial stromal nodules, highly cellular leiomyomas. 61
15823122 2005
37
Endometrial stromal tumor with limited infiltration and probable extrauterine metastasis: report of a case. 61
15692954 2005
38
[Endometrial stromal nodule: a case report]. 61
15453037 2004
39
Simultaneous occurrence of hepatic focal nodular hyperplasia and uterine endometrial stromal nodule in a patient having treated breast infiltrating ductal carcinoma. 61
12780434 2003
40
CD10 is a sensitive and diagnostically useful immunohistochemical marker of normal endometrial stroma and of endometrial stromal neoplasms. 61
11532038 2001
41
Hormonal treatment of an endometrial stromal nodule followed by local excision. 61
10912400 1999
42
Endometrial stromal nodule with retiform sex-cord-like differentiation. 61
9689655 1998
43
[Transcervical electric resection in submucous myomas]. 61
7970074 1994
44
Ultrastructure of an endometrial stromal nodule with skeletal muscle. 61
8266600 1993
45
Endometrial stromal nodule with smooth and skeletal muscle components simulating stromal sarcoma. 61
1399235 1992
46
Primary uterine endometrial stromal neoplasms. A clinicopathologic study of 117 cases. 61
2327549 1990
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Variations for Endometrial Stromal Nodule

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Expression for Endometrial Stromal Nodule

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Search GEO for disease gene expression data for Endometrial Stromal Nodule.
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Pathways for Endometrial Stromal Nodule

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GO Terms for Endometrial Stromal Nodule

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Cellular components related to Endometrial Stromal Nodule according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nucleus GO:0005634 9.61 ZC3H7B ZC3H7A YWHAE SUZ12 PHF1 MEAF6
2 ESC/E(Z) complex GO:0035098 8.62 SUZ12 PHF1

Biological processes related to Endometrial Stromal Nodule according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of gene expression, epigenetic GO:0045814 9.32 SUZ12 PHF1
2 posttranscriptional regulation of gene expression GO:0010608 9.26 ZC3H7B ZC3H7A
3 chromatin organization GO:0006325 9.26 SUZ12 PHF1 MEAF6 MBTD1
4 production of miRNAs involved in gene silencing by miRNA GO:0035196 9.16 ZC3H7B ZC3H7A
5 negative regulation of histone H3-K27 methylation GO:0061086 8.62 PHF1 EZHIP

Molecular functions related to Endometrial Stromal Nodule according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 miRNA binding GO:0035198 9.16 ZC3H7B ZC3H7A
2 RNA polymerase II transcription corepressor binding GO:0001226 8.96 SUZ12 PHF1
3 methylated histone binding GO:0035064 8.8 SUZ12 PHF1 MBTD1
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Sources for Endometrial Stromal Nodule

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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