ESS
MCID: END031
MIFTS: 52

Endometrial Stromal Sarcoma (ESS)

Categories: Cancer diseases, Endocrine diseases, Rare diseases, Reproductive diseases

Aliases & Classifications for Endometrial Stromal Sarcoma

MalaCards integrated aliases for Endometrial Stromal Sarcoma:

Name: Endometrial Stromal Sarcoma 12 76 53 59 15 73
Ess 12 53
Endometrial Stromal Sarcoma, High Grade 12
Undifferentiated Endometrial Sarcoma 12
Stromal Sarcoma of the Corpus Uteri 59
Undifferentiated Stromal Sarcoma 73
Sarcoma, Endometrial Stromal 44
Sarcoma Endometrial Stromal 55

Classifications:



External Ids:

Disease Ontology 12 DOID:4226
MeSH 44 D018203
NCIt 50 C8973
SNOMED-CT 68 70555003
Orphanet 59 ORPHA213711
MESH via Orphanet 45 D018203
UMLS via Orphanet 74 C0206630
ICD10 via Orphanet 34 C54.1

Summaries for Endometrial Stromal Sarcoma

NIH Rare Diseases : 53 Endometrial stromal sarcoma is a rare form of cancer that occurs due to abnormal and uncontrolled cell growth in the uterus. Endometrial stromal sarcoma, specifically, develops in the supporting connective tissue (stroma) of the uterus. Signs and symptoms of the condition include abnormal uterine bleeding (i.e. bleeding that is not part of menstrual periods or bleeding after menopause); abdominal pain and/or distension; and frequent urination. The exact underlying cause of endometrial stromal sarcoma is currently unknown. Most cases occur sporadically in people with no family history of the condition. Treatment varies based on the severity of the condition but may include surgery, radiation therapy, chemotherapy, and/or hormone therapy.

MalaCards based summary : Endometrial Stromal Sarcoma, also known as ess, is related to endometrial stromal nodule and endometriosis. An important gene associated with Endometrial Stromal Sarcoma is SUZ12 (SUZ12, Polycomb Repressive Complex 2 Subunit), and among its related pathways/superpathways are Striated Muscle Contraction and Regulation of Telomerase. The drugs Abraxane and Abstral have been mentioned in the context of this disorder. Affiliated tissues include uterus, smooth muscle and lung, and related phenotypes are cardiovascular system and cellular

Disease Ontology : 12 An endometrial stromal tumor that has_material_basis in connective tissue.

Wikipedia : 76 Endometrial stromal sarcoma is a malignant subtype of endometrial stromal tumor arising from the stroma... more...

Related Diseases for Endometrial Stromal Sarcoma

Diseases related to Endometrial Stromal Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 187)
# Related Disease Score Top Affiliating Genes
1 endometrial stromal nodule 31.8 BCOR CYP19A1 JAZF1 MEAF6 MME NUTM2A
2 endometriosis 31.5 CYP19A1 ESR1 PGR
3 spindle cell sarcoma 31.2 ACTC1 DES VIM
4 leiomyosarcoma 31.0 ACTC1 DES KIT MB PGR VIM
5 adenomyosis 30.9 CYP19A1 ESR1 MME PGR
6 carcinosarcoma 30.7 ACTC1 DES KIT MME PGR VIM
7 myoma 30.7 CYP19A1 ESR1 PGR
8 uterine carcinosarcoma 30.7 KIT MME PGR
9 intravenous leiomyomatosis 30.7 DES ESR1 MME
10 leiomyoma 30.6 ACTC1 CYP19A1 DES ESR1 KIT MME
11 smooth muscle tumor 30.6 ACTC1 DES ESR1 KIT PGR VIM
12 lymphangioleiomyomatosis 30.6 DES ESR1 PGR
13 uterine sarcoma 30.5 CYP19A1 DES ESR1 KIT MB MME
14 endometriosis of ovary 30.4 CYP19A1 ESR1 PGR
15 endometrial adenocarcinoma 30.3 ESR1 MALAT1 PGR
16 adenofibroma 30.3 ACTC1 INHA MME VIM
17 myxoid leiomyosarcoma 30.3 ACTC1 BCOR MME PGR YWHAE
18 renal cell carcinoma, nonpapillary 30.1 KIT MALAT1 MME VIM
19 endometrial stromal tumor 30.0 BCOR JAZF1 MEAF6 MME NUTM2A PGR
20 vaginal endometrial stromal sarcoma 12.5
21 uterine corpus endometrial stromal sarcoma 12.4
22 cervical endometrial stromal sarcoma 12.4
23 empty sella syndrome 11.7
24 sarcoma 11.3
25 euthyroid sick syndrome 11.1
26 vestibular gland benign neoplasm 10.4 ESR1 PGR
27 bartholin's gland adenoma 10.4 ESR1 PGR
28 myofibroma 10.4 DES MB
29 vulvar syringoma 10.4 ESR1 PGR
30 glassy cell carcinoma of the cervix 10.4 ESR1 PGR
31 infantile digital fibromatosis 10.4 DES VIM
32 adenocarcinoma 10.3
33 breast myofibroblastoma 10.3 ESR1 MME
34 vulvar benign neoplasm 10.3 ESR1 PGR
35 lymphangiomatosis 10.3 DES PGR VIM
36 lymphangiectasis 10.3 ACTC1 VIM
37 trigonitis 10.3 ESR1 PGR
38 vulvar leiomyoma 10.3 ESR1 PGR
39 epulis 10.3 DES PGR VIM
40 progesterone-receptor positive breast cancer 10.3 CYP19A1 ESR1 PGR
41 calcifying aponeurotic fibroma 10.3 ACTC1 PGR
42 gender identity disorder 10.3 CYP19A1 ESR1 PGR
43 fibroblastic rheumatism 10.3 ACTC1 DES
44 estrogen excess 10.3 CYP19A1 ESR1 PGR
45 mammographic density 10.3 CYP19A1 ESR1 PGR
46 angiolipoma 10.3 ACTC1 DES VIM
47 cervical carcinosarcoma 10.3 ESR1 MME PGR
48 cutaneous leiomyosarcoma 10.3 ACTC1 DES VIM
49 mesenchymoma 10.3 DES MB
50 endometrial mucinous adenocarcinoma 10.3 ESR1 PGR VIM

Graphical network of the top 20 diseases related to Endometrial Stromal Sarcoma:



Diseases related to Endometrial Stromal Sarcoma

Symptoms & Phenotypes for Endometrial Stromal Sarcoma

MGI Mouse Phenotypes related to Endometrial Stromal Sarcoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.18 ACTC1 BCOR CCND1 CYP19A1 DES ESR1
2 cellular MP:0005384 10.15 ACTC1 BCOR CCND1 CYP19A1 DES ESR1
3 homeostasis/metabolism MP:0005376 10.03 ACTC1 CCND1 CYP19A1 DES ESR1 INHA
4 hematopoietic system MP:0005397 10.02 BCOR CCND1 CYP19A1 ESR1 INHA KIT
5 mortality/aging MP:0010768 9.93 ACTC1 BCOR CCND1 DES ESR1 INHA
6 muscle MP:0005369 9.61 ACTC1 CYP19A1 DES ESR1 KIT MB
7 neoplasm MP:0002006 9.1 CCND1 ESR1 INHA KIT PGR SUZ12

Drugs & Therapeutics for Endometrial Stromal Sarcoma

FDA approved drugs:

(show top 50) (show all 204)
# Drug Name Active Ingredient(s) 18 Company Approval Date
1
Abraxane 18 49 PACLITAXEL Celgene October 2012
2
Abstral 18 FENTANYL (citrate) ProStrakan January 2011
3
Actiq 18 FENTANYL (citrate) Anesta Corporation November 1998
4
Adcetris 18 49 BRENTUXIMAB VEDOTIN Seattle Genetics August 2011
5
Afinitor 18 49 EVEROLIMUS Novartis March 2009
6
Akynzeo 18 49 NETUPITANT AND PALONOSETRON (hydrochloride) Helsinn October 2014
7
Alimta 18 49 PEMETREXED (also Pemetrexed Disodium) Eli Lilly February 2004
8
Aloxi 18 49 PALONOSETRON (hydrochloride) MGI Pharma, Helsinn Healthcare August 2003
9
Aredia 18 49 PAMIDRONATE DISODIUM Chiron August 1996
10
Arimidex 18 49 ANASTROZOLE AstraZeneca January 1996
11
Aromasin Tablets 18 49 EXEMESTANE Pharmacia & Upjohn October 21. 1999
12
Arranon 18 49 NELARABINE GlaxoSmithKline October 2005
13
Arzerra 18 49 OFATUMUMAB GlaxoSmithKline October 2009
14
Avastin 18 49 BEVACIZUMAB Genentech July 2009
15
Beleodaq 18 49 BELINOSTAT Spectrum Pharmaceuticals July 2014
16
Bexxar 18 49 TOSITUMOMAB; IODINE I 131 TOSITUMOMAB Corixa June 2003
17
Blincyto 18 49 BLINATUMOMAB Amgen December 2014
18
Bosulif 18 49 BOSUTINIB MONOHYDRATE Pfizer September 2012
19
Busulfex 18 49 BUSULFAN Orphan Medical February 1999
20
Campath 18 49 ALEMTUZUMAB Berlex Laboratories May 2001
21
Campostar 18 49 IRINOTECAN HYDROCHLORIDE Pharmacia & Upjohn June 1996
22
CEA-Scan 18 Immunomedics April 1996
23
Cervarix 18 49 Human Papillomavirus Bivalent (Types 16 and 18) Vaccine, Recombinant GlaxoSmithKline October 2009
24
Cometriq 18 49 CABOZANTINIB S-MALATE Exelixis November 2012
25
Cyramza 18 49 RAMUCIRUMAB Eli Lilly April 2014
26
Degarelix 18 49 degarelix Ferring Pharmaceuticals December of 2008
27
Doxil 18 49 DOXORUBICIN HYDROCHLORIDE Alza June 1999
28
Elitek 18 49 RASBURICASE sanofi-aventis October 2009
29
Eloxatin 18 49 OXALIPLATIN Sanofi-aventis August 2002
30
Emend 18 49 APREPITANT FOSAPREPITANT DIMEGLUMINE Merck March 2003
31
Erbitux 18 49 CETUXIMAB Imclone, Bristol-Myers Squibb February 2004
32
Erivedge 18 49 VISMODEGIB Genentech January 2012
33
Ethyol 18 AMIFOSTINE Alza December 8, 1995
34
Eulexin 18 FLUTAMIDE Schering-Plough June 1996
35
Evista 18 49 RALOXIFENE HYDROCHLORIDE Eli Lilly September 2007
36
Farydak 18 49 PANOBINOSTAT LACTATE Novartis February 2015
37
Faslodex 18 49 FULVESTRANT AstraZeneca April 2002
38
Femara 18 49 LETROZOLE Novartis January 2001
39
Folotyn 18 49 PRALATREXATE Allos Therapeutics September 2009
40
Fusilev 18 LEVOLEUCOVORIN CALCIUM Spectrum Pharmaceuticals March of 2008
41
Gardasil 18 49 quadrivalent human papillomavirus (types 6, 11, 16, 18) recombinant vaccine Merck June 2006
42
Gazyva 18 49 OBINUTUZUMAB Genentech October of 2013
43
Gemzar 18 49 GEMCITABINE HYDROCHLORIDE Eli Lilly May 1996
44
Gilotrif 18 49 AFATINIB DIMALEATE Boehringer Ingelheim July 2013
45
Gleevec 18 49 IMATINIB MESYLATE Novartis May 2001
46
Gliadel Wafer 18 49 CARMUSTINE Rhone-Poulenc Rorer, Guilford Pharmaceuticals February 1997
47
Halaven 18 49 ERIBULIN MESYLATE Eisai November 2010
48
Herceptin 18 49 TRASTUZUMAB Genentech October 1998
49
Hycamtin 18 49 TOPOTECAN HYDROCHLORIDE GlaxoSmithKline/ SmithKline Beecham October 2007/May 1996
50
Ibrance 18 49 PALBOCICLIB Pfizer February 2015

Drugs for Endometrial Stromal Sarcoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 77)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Lenograstim Approved, Investigational Phase 3 135968-09-1
2
Ifosfamide Approved Phase 3 3778-73-2 3690
3
Doxorubicin Approved, Investigational Phase 3,Phase 2 23214-92-8 31703
4
Mechlorethamine Approved, Investigational Phase 3 51-75-2 4033
5
Histamine Approved, Investigational Phase 3 51-45-6, 75614-87-8 774
6
Cyproheptadine Approved Phase 3 129-03-3 2913
7
Doxil Approved June 1999 Phase 3,Phase 2 31703
8 Antineoplastic Agents, Alkylating Phase 3,Phase 2
9 Alkylating Agents Phase 3,Phase 2
10
Isophosphamide mustard Phase 3 0
11 Anti-Bacterial Agents Phase 3,Phase 2
12 Topoisomerase Inhibitors Phase 3,Phase 2
13 Antibiotics, Antitubercular Phase 3,Phase 2
14 Gastrointestinal Agents Phase 3,Phase 2
15 Serotonin Agents Phase 3
16 Anti-Allergic Agents Phase 3
17 Serotonin Antagonists Phase 3
18 Histamine H1 Antagonists Phase 3
19
Histamine Phosphate Phase 3 51-74-1 65513
20 Antipruritics Phase 3
21 Neurotransmitter Agents Phase 3
22 Dermatologic Agents Phase 3
23 Histamine Antagonists Phase 3
24
Serotonin Investigational, Nutraceutical Phase 3 50-67-9 5202
25
Dacarbazine Approved, Investigational Phase 2 4342-03-4 5351166
26
Temozolomide Approved, Investigational Phase 2 85622-93-1 5394
27
Hydrocortisone acetate Approved, Vet_approved Phase 2 50-03-3
28
Hydrocortisone Approved, Vet_approved Phase 2 50-23-7 5754
29
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 2 1177-87-3
30
Dexamethasone Approved, Investigational, Vet_approved Phase 2 50-02-2 5743
31
Mifepristone Approved, Investigational Phase 2 84371-65-3 55245
32
Sunitinib Approved, Investigational Phase 2 557795-19-4, 341031-54-7 5329102
33
Trabectedin Approved, Investigational Phase 2 114899-77-3 108150
34
Paclitaxel Approved, Vet_approved Phase 2 33069-62-4 36314
35
Nivolumab Approved Phase 2 946414-94-4
36
Letrozole Approved, Investigational Phase 2 112809-51-5 3902
37
Exemestane Approved, Investigational Phase 2 107868-30-4 60198
38
Anastrozole Approved, Investigational Phase 2 120511-73-1 2187
39
Saracatinib Investigational Phase 2 379231-04-6
40
Trebananib Investigational Phase 2 894356-79-7
41 Antineoplastic Agents, Hormonal Phase 2
42 Cortisol succinate Phase 2
43
protease inhibitors Phase 2
44 BB 1101 Phase 2
45 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 2
46 Hormone Antagonists Phase 2
47 Hormones Phase 2
48 glucocorticoids Phase 2
49 Autonomic Agents Phase 2
50 Antiemetics Phase 2

Interventional clinical trials:

(show all 22)
# Name Status NCT ID Phase Drugs
1 Radiation Therapy or No Further Treatment Following Surgery in Treating Patients With Cancer of the Uterus Completed NCT00002459 Phase 3
2 Surgery With or Without Combination Chemotherapy in Treating Patients With Lung Metastases From Soft Tissue Sarcoma Completed NCT00002764 Phase 3 doxorubicin hydrochloride;ifosfamide
3 Surgery With or Without Chemotherapy in Treating Patients With Soft Tissue Sarcoma Completed NCT00002641 Phase 3 doxorubicin hydrochloride;ifosfamide;isolated perfusion
4 Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for Cancer Terminated NCT01132547 Phase 3 cyproheptadine hydrochloride
5 Temozolomide in Treating Patients With Advanced Soft Tissue Sarcoma Unknown status NCT00003718 Phase 2 temozolomide
6 Medical Safety Follow-up Study for Patients Who Received More Than 28 Days of Total Exposure to BGG492 Completed NCT02150213 Phase 2 BGG492
7 Mifepristone for Patients With Endometrial Cancer and LGESS Completed NCT00505739 Phase 2 Mifepristone
8 Chemotherapy in Treating Patients With Sarcoma of the Uterus Completed NCT00005643 Phase 2 pegylated liposomal doxorubicin hydrochloride
9 AZD0530 in Treating Patients With Recurrent Locally Advanced or Metastatic Soft Tissue Sarcoma Completed NCT00659360 Phase 2 saracatinib
10 BI 2536 in Treating Patients With Recurrent or Metastatic Solid Tumors Completed NCT00526149 Phase 2 BI 2536
11 Sunitinib in Treating Patients With Metastatic, Locally Advanced, or Locally Recurrent Sarcomas Completed NCT00474994 Phase 2 sunitinib malate
12 Ecteinascidin 743 in Treating Patients With Advanced Soft Tissue Sarcoma Completed NCT00003939 Phase 2 trabectedin
13 STI571 in Treating Patients With Recurrent or Refractory Soft Tissue Sarcoma Completed NCT00006357 Phase 1, Phase 2 imatinib mesylate
14 Combination Chemotherapy in Treating Patients With Endometrial Cancer, Fallopian Tube Cancer, or Sarcoma of the Female Reproductive Tract Completed NCT00003334 Phase 2 paclitaxel;pegylated liposomal doxorubicin hydrochloride
15 Perifosine in Treating Patients With Metastatic or Locally Advanced Soft Tissue Sarcoma Completed NCT00053794 Phase 2 perifosine
16 Thalidomide in Treating Patients With Gynecologic Sarcomas Completed NCT00006005 Phase 2 thalidomide
17 Trebananib in Treating Patients With Persistent or Recurrent Endometrial Cancer Completed NCT01210222 Phase 2
18 Phase II Study of Imatinib Mesylate in Patients With Life Threatening Malignant Rare Diseases Completed NCT00154388 Phase 2 Imatinib mesylate
19 A Study of Nivolumab in Selected Uterine Cancer Patients Recruiting NCT03241745 Phase 2 Nivolumab
20 Evaluation of Clinical Impact of Interruption VS Maintenance of AI in Patients With Locally Advanced/ Metastatic Low Grade Endometrial Stromal Sarcoma (LGESS) Not yet recruiting NCT03624244 Phase 2 Aromatase Inhibitors
21 A Phase II of Nivolumab Plus Ipilimumab in Non-resectable Sarcoma and Endometrial Carcinoma Not yet recruiting NCT02982486 Phase 2 Ipilimumab;Nivolumab
22 Collecting Tumor Samples From Patients With Gynecological Tumors Completed NCT00897442

Search NIH Clinical Center for Endometrial Stromal Sarcoma

Cochrane evidence based reviews: sarcoma, endometrial stromal

Genetic Tests for Endometrial Stromal Sarcoma

Anatomical Context for Endometrial Stromal Sarcoma

MalaCards organs/tissues related to Endometrial Stromal Sarcoma:

41
Uterus, Smooth Muscle, Lung, Ovary, Breast, Bone, Colon

Publications for Endometrial Stromal Sarcoma

Articles related to Endometrial Stromal Sarcoma:

(show top 50) (show all 653)
# Title Authors Year
1
Hepatic endometrial stromal sarcoma. ( 29843927 )
2018
2
A remarkable response to pazopanib, despite recurrent liver toxicity, in a patient with a high grade endometrial stromal sarcoma, a case report. ( 29357824 )
2018
3
Recurrence after fertility-preserving surgery for low-grade endometrial stromal sarcoma. ( 29974555 )
2018
4
Endometrial Stromal Sarcoma With Hyalinizing Giant Rosettes, Mimicking Low-Grade Fibromyxoid Sarcoma. ( 29623744 )
2018
5
Adjuvant Hormonal Therapy for Low-Grade Endometrial Stromal Sarcoma. ( 29843577 )
2018
6
Morphological and immunohistochemical diversity of endometrial stromal sarcoma in rats. ( 29749998 )
2018
7
Gene expression profiling of low-grade endometrial stromal sarcoma indicates fusion protein-mediated activation of the Wnt signaling pathway. ( 29544705 )
2018
8
Investigation of hormone receptor expression and its prognostic value in endometrial stromal sarcoma. ( 29869299 )
2018
9
Impact of oophorectomy and hormone suppression in low grade endometrial stromal sarcoma: A multicenter review. ( 29534832 )
2018
10
Molecular biomarkers for uterine leiomyosarcoma and endometrial stromal sarcoma. ( 29660202 )
2018
11
Immunohistochemical Expression of Different Subtypes of Cytokeratins by Endometrial Stromal Sarcoma. ( 29406332 )
2018
12
Treatment of low-grade endometrial stromal sarcoma in a nulligravid woman. ( 29887484 )
2018
13
Identification of an EPC2-PHF1 fusion transcript in low-grade endometrial stromal sarcoma. ( 29721194 )
2018
14
Next-generation Sequencing of an Ovarian Spindle Cell Tumor Identified an Ovarian Low-grade Endometrial Stromal Sarcoma: A Rare Entity. ( 30028354 )
2018
15
Low-grade endometrial stromal sarcoma presenting as multiple pulmonary nodules: A potential pitfall in fine needle aspiration and core biopsy specimens - A Cytological - Pathological Correlation. ( 30055523 )
2018
16
Novel EPC1 gene fusions in endometrial stromal sarcoma. ( 30144186 )
2018
17
Endometrial Stromal Sarcoma Recurrence in the Caecum. ( 30174981 )
2018
18
YWHAE-NUTM2A/B Translocated High-grade Endometrial Stromal Sarcoma Commonly Expresses CD56 and CD99. ( 30252726 )
2018
19
Low-Grade Endometrial Stromal Sarcoma in a Postmenopausal Woman with Third-Degree Uterovaginal Prolapse: A Rare Case with Review of the Literature. ( 30294191 )
2018
20
Low-Grade Endometrial Stromal Sarcoma - a Review. ( 30317238 )
2018
21
Endometrial Stromal Sarcoma Arising from Endometrial Polyp: A Case Report. ( 30381725 )
2018
22
Low-grade endometrial stromal sarcoma combined with leiomyoma (stromomyoma): A bizarre tumor of the uterus in a premenopausal woman. ( 30476382 )
2018
23
Aromatase inhibitor therapy for endometrial stromal sarcoma - two-centre experience. ( 30508212 )
2018
24
Endometrial stromal sarcoma in a 27-year-old woman. Case report and literature review. ( 30534836 )
2018
25
Suitability of the Epworth Sleepiness Scale (ESS) for Economic Evaluation: An Assessment of Its Convergent and Discriminant Validity. ( 27754703 )
2018
26
Is reproducibility inside the bag? Special issue fundamentals and applications of sonochemistry ESS-15. ( 28377103 )
2018
27
The ESS and replicator equation in matrix games under time constraints. ( 29332298 )
2018
28
Discovering the effect of nonlocal payoff calculation on the stabilty of ESS: Spatial patterns of Hawk-Dove game in metapopulations. ( 29355541 )
2018
29
Koskinen et al. Long-term follow-up after ESS and balloon sinoplasty: comparison of symptom reduction and patient satisfaction. Acta Oto-Laryngol 2016; 136: 532-536. ( 29532720 )
2018
30
Optimization of moderators and beam extraction at the ESS. ( 29657564 )
2018
31
Sleep-disordered breathing in patients with cardiovascular diseases cannot be detected by ESS, STOP-BANG, and Berlin questionnaires. ( 29845331 )
2018
32
Effect of ESS on Olfactory Threshold of Patients with CRS without Nasal Polyps. ( 29993224 )
2018
33
The Emergency Surgery Score (ESS) accurately predicts the occurrence of postoperative complications in emergency surgery patients: A reply. ( 30036260 )
2018
34
Can the emergency surgery score (ESS) be used as a triage tool predicting the postoperative need for an ICU admission? ( 30172358 )
2018
35
ESS: A Tool for Genome-Scale Quantification of Essentiality Score for Reaction/Genes in Constraint-Based Modeling. ( 30323767 )
2018
36
BCOR is a robust diagnostic immunohistochemical marker of genetically diverse high-grade endometrial stromal sarcoma, including tumors exhibiting variant morphology. ( 28621321 )
2017
37
Magnetic resonance imaging features of endometrial stromal sarcoma: a case description. ( 28275572 )
2017
38
Androgen Receptor Expression in Endometrial Stromal Sarcoma: Correlation With Clinicopathologic Features. ( 28114189 )
2017
39
A recurrent endometrial stromal sarcoma harbors the novel fusion JAZF1-BCORL1. ( 28331900 )
2017
40
Cardiac metastatic endometrial stromal sarcoma 17 years after hysterectomy. ( 28967156 )
2017
41
Oncogenic HrasG12V expression plus knockdown of Cdkn2a using ecotropic lentiviral vectors induces high-grade endometrial stromal sarcoma. ( 28982163 )
2017
42
Primary low-grade endometrial stromal sarcoma arising in the vagina: report of an unusual case and literature review. ( 29218216 )
2017
43
Endometrial Stromal Sarcoma of the Uterus: Magnetic Resonance Imaging Findings Including Apparent Diffusion Coefficient Value and Its Correlation With Ki-67 Expression. ( 28906310 )
2017
44
Clinicopathological characteristics and treatment strategies for patients with low-grade endometrial stromal sarcoma. ( 28403089 )
2017
45
Endometrial stromal sarcoma-A retropsective analysis of factors affecting recurrence. ( 28738297 )
2017
46
A Rare Collision Tumour of Uterus- Squamous Cell Carcinoma and Endometrial Stromal Sarcoma. ( 28384878 )
2017
47
Low-grade endometrial stromal sarcoma with extensive sex cord differentiation, heterologous elements, and complex atypical hyperplasia: Case report and review of literature. ( 28054022 )
2017
48
Low-grade and high-grade endometrial stromal sarcoma: A National Cancer Database study. ( 28596015 )
2017
49
YWHAE Rearrangement in a Purely Conventional Low-grade Endometrial Stromal Sarcoma that Transformed Over Time to High-grade Sarcoma: Importance of Molecular Testing. ( 28863072 )
2017
50
YWHAE-rearranged high-grade endometrial stromal sarcoma: Two-center case series and response to chemotherapy. ( 28390819 )
2017

Variations for Endometrial Stromal Sarcoma

Expression for Endometrial Stromal Sarcoma

Search GEO for disease gene expression data for Endometrial Stromal Sarcoma.

Pathways for Endometrial Stromal Sarcoma

Pathways related to Endometrial Stromal Sarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.36 ACTC1 DES VIM
2 11.25 CCND1 ESR1 YWHAE
3 10.66 BCOR ESR1 YWHAE
4 10.3 CYP19A1 INHA PGR
5 9.76 CYP19A1 ESR1

GO Terms for Endometrial Stromal Sarcoma

Cellular components related to Endometrial Stromal Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ESC/E(Z) complex GO:0035098 8.62 PHF1 SUZ12

Biological processes related to Endometrial Stromal Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 male gonad development GO:0008584 9.33 ESR1 INHA KIT
2 androgen metabolic process GO:0008209 9.32 CYP19A1 ESR1
3 mammary gland alveolus development GO:0060749 9.26 CCND1 ESR1
4 positive regulation of phospholipase C activity GO:0010863 8.96 ESR1 KIT
5 muscle filament sliding GO:0030049 8.8 ACTC1 DES VIM

Sources for Endometrial Stromal Sarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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